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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:peptide hormone
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Accession:CHEBI:25905 term browser browse the term
Definition:Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.
Synonyms:related_synonym: peptide hormones;   polypeptide hormone



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angiotensin II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 increases expression ISO Angiotensin II results in increased expression of AGTR2 mRNA; Angiotensin II results in increased expression of AGTR2 protein CTD PMID:12969123 NCBI chr  X:21,484,624...21,488,833
Ensembl chr  X:21,484,544...21,489,164
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Angiotensin II results in increased expression of EDNRB protein CTD PMID:15007106 NCBI chr14:103,814,615...103,844,508
Ensembl chr14:103,814,625...103,844,402
JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation ISO Angiotensin II increases phosphorylation of JAK2 protein in liver RGD PMID:22613986 RGD:127285667 NCBI chr19:29,251,803...29,313,095
Ensembl chr19:29,251,828...29,313,080
JBrowse link
G Nphs1 nephrosis 1, nephrin multiple interactions EXP angiotensin II inhibits reaction [fluvastatin increases expression of Nphs1 protein in kidney] RGD PMID:19188342 RGD:38596324 NCBI chr 7:30,458,207...30,488,623
Ensembl chr 7:30,458,315...30,487,223
JBrowse link
argipressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1a arginine vasopressin receptor 1A increases activity
multiple interactions
ISO Arginine Vasopressin results in increased activity of AVPR1A protein
vasopressin, 1-(1-mercaptocyclohexaneacetic acid)-2-(O- methyl-L-tyrosine)-8-L-arginine- inhibits the reaction [Arginine Vasopressin results in increased activity of AVPR1A protein]
CTD PMID:31323226 NCBI chr10:122,448,499...122,453,453
Ensembl chr10:122,448,499...122,453,452
JBrowse link
G Hspb1 heat shock protein 1 increases expression
multiple interactions
ISO Arginine Vasopressin results in increased expression of HSPB1 mRNA; Arginine Vasopressin results in increased expression of HSPB1 protein
Pentobarbital inhibits the reaction [Arginine Vasopressin results in increased expression of HSPB1 mRNA]; Pentobarbital inhibits the reaction [Arginine Vasopressin results in increased expression of HSPB1 protein]
CTD PMID:10839933 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory increases phosphorylation ISO Arginine Vasopressin results in increased phosphorylation of MYL9 protein CTD PMID:15347643 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Nppa natriuretic peptide type A decreases response to substance EXP NPPA protein results in decreased susceptibility to Arginine Vasopressin CTD PMID:8188982 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079
JBrowse link
calcitonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hcrt hypocretin decreases expression ISO salmon calcitonin results in decreased expression of HCRT mRNA CTD PMID:12686383 NCBI chr11:100,761,693...100,762,931
Ensembl chr11:100,761,069...100,762,931
JBrowse link
G Pmch pro-melanin-concentrating hormone decreases expression ISO salmon calcitonin results in decreased expression of PMCH mRNA CTD PMID:12686383 NCBI chr10:88,091,072...88,092,374
Ensembl chr10:88,091,072...88,092,375
JBrowse link
corticotropin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases activity ISO Adrenocorticotropic Hormone results in increased activity of ADA protein CTD PMID:8868375 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases abundance ISO CALCA protein results in increased abundance of Adrenocorticotropic Hormone CTD PMID:12639925 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases activity ISO Adrenocorticotropic Hormone results in decreased activity of CNP protein CTD PMID:3030154 NCBI chr11:100,574,909...100,591,875
Ensembl chr11:100,574,904...100,591,729
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion
ISO Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]; E 4031 inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Tetraethylammonium promotes the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone] CTD PMID:18835572 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects abundance ISO CYP17A1 protein affects the abundance of Adrenocorticotropic Hormone CTD PMID:18645707 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Gh growth hormone multiple interactions ISO Adrenocorticotropic Hormone inhibits the reaction [INS protein results in increased secretion of GH1 protein] CTD PMID:3008584 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A multiple interactions
affects expression
ISO Bupropion inhibits the reaction [Adrenocorticotropic Hormone affects the expression of HTR2A mRNA] CTD PMID:18239281 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Ins2 insulin II multiple interactions ISO Adrenocorticotropic Hormone inhibits the reaction [INS protein results in increased secretion of GH1 protein] CTD PMID:3008584 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects abundance ISO NR3C1 gene polymorphism affects the abundance of Adrenocorticotropic Hormone CTD PMID:17716631 NCBI chr18:39,410,545...39,519,421
Ensembl chr18:39,410,545...39,519,421
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B multiple interactions EXP Cocaine promotes the reaction [PPP1R1B protein results in increased abundance of Adrenocorticotropic Hormone] CTD PMID:10516482 NCBI chr11:98,348,406...98,357,796
Ensembl chr11:98,348,404...98,357,796
JBrowse link
G Ucn2 urocortin 2 increases abundance EXP UCN2 protein results in increased abundance of Adrenocorticotropic Hormone CTD PMID:16330704 NCBI chr 9:108,986,163...108,987,164
Ensembl chr 9:108,986,010...108,987,164
JBrowse link
corticotropin-releasing hormone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr1 corticotropin releasing hormone receptor 1 increases expression
decreases activity
multiple interactions
ISO Corticotropin-Releasing Hormone results in increased expression of CRHR1 mRNA
Corticotropin-Releasing Hormone results in decreased activity of CRHR1 protein
Pentobarbital inhibits the reaction [Corticotropin-Releasing Hormone results in decreased activity of CRHR1 protein]; Pentobarbital inhibits the reaction [Corticotropin-Releasing Hormone results in increased expression of CRHR1 mRNA]
CTD PMID:12093084 NCBI chr11:104,130,463...104,175,523
Ensembl chr11:104,132,855...104,175,523
JBrowse link
gastrin-17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC2 CTD PMID:17704804 NCBI chr 9:7,818,226...7,837,131
Ensembl chr 9:7,818,227...7,837,064
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC3 CTD PMID:17704804 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186
JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC2; [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC3; [gastrin 17 co-treated with CCKBR protein] results in increased expression of IER3 mRNA CTD PMID:17704804 NCBI chr 7:105,425,676...105,436,339
Ensembl chr 7:105,425,731...105,470,898
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases secretion ISO gastrin 17 results in increased secretion of CXCL8 protein CTD PMID:15623601 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in increased expression of IER3 mRNA CTD PMID:17704804 NCBI chr17:35,821,713...35,822,911
Ensembl chr17:35,821,684...35,822,923
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 decreases activity ISO gastrin 17 results in decreased activity of NFKB1 protein CTD PMID:15623601 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) decreases activity ISO gastrin 17 results in decreased activity of RELA protein CTD PMID:15623601 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Sele selectin, endothelial cell decreases expression ISO gastrin 17 results in decreased expression of SELE protein CTD PMID:15623601 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
ghrelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 (brain) multiple interactions ISO Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA] CTD PMID:31468622 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions ISO Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] CTD PMID:31468622 NCBI chr17:30,901,867...30,936,510
Ensembl chr17:30,901,817...30,940,791
JBrowse link
G Mir33 microRNA 33 multiple interactions ISO Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA] CTD PMID:31468622 NCBI chr15:82,198,122...82,198,190
Ensembl chr15:82,198,122...82,198,190
JBrowse link
glucagon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of ACTA2 mRNA] CTD PMID:29988851 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased expression of and results in decreased secretion of ADIPOQ protein] CTD PMID:29988851 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Cat catalase multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased activity of CAT protein] CTD PMID:29988851 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 mRNA] CTD PMID:29988851 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of COL1A1 mRNA] CTD PMID:29988851 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased expression of CPT1A mRNA] CTD PMID:29988851 NCBI chr19:3,322,326...3,385,735
Ensembl chr19:3,322,334...3,385,733
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [Glucagon co-treated with Cyclic AMP] results in increased phosphorylation of CREB1 protein CTD PMID:22676303 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Fasn fatty acid synthase multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of FASN mRNA] CTD PMID:29988851 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions EXP Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein]; Glucagon analog promotes the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of FGF21 protein] CTD PMID:29988851 NCBI chr 7:45,613,890...45,615,490
Ensembl chr 7:45,613,886...45,615,490
JBrowse link
G G6pc glucose-6-phosphatase, catalytic multiple interactions ISO [Glucagon co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA] CTD PMID:22676303 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G Gcgr glucagon receptor multiple interactions EXP Glucagon analog binds to and results in increased activity of GCGR protein CTD PMID:29988851 NCBI chr11:120,529,185...120,538,989
Ensembl chr11:120,530,699...120,538,986
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP Glucagon analog binds to and results in increased activity of GLP1R protein CTD PMID:29988851 NCBI chr17:30,901,867...30,936,510
Ensembl chr17:30,901,817...30,940,791
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of IL6 protein] CTD PMID:29988851 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Ins1 insulin I multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of INS1 protein] CTD PMID:29988851 NCBI chr19:52,264,297...52,265,015
Ensembl chr19:52,264,297...52,265,476
JBrowse link
G Lep leptin multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of LEP protein] CTD PMID:29988851 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lepr leptin receptor multiple interactions EXP Glucagon analog inhibits the reaction [[LEPR gene mutant form results in increased oxidation of Lipids] which results in increased abundance of Thiobarbituric Acid Reactive Substances]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased expression of PPARA mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased oxidation of and results in decreased metabolism of Fatty Acids]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Cholesterol]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Triglycerides]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Urea]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of ACTA2 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of IL6 protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of INS1 protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of LEP protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of FASN mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of MMP9 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of SCD1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of SREBF1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of TGFB1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of TNF mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased oxidation of Lipids]; Glucagon analog promotes the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of FGF21 protein] CTD PMID:29988851 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of MMP9 mRNA] CTD PMID:29988851 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions ISO [Glucagon co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA] CTD PMID:22676303 NCBI chr 2:173,153,073...173,159,274
Ensembl chr 2:173,153,048...173,159,273
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in decreased expression of PPARA mRNA] CTD PMID:29988851 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions ISO [Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased phosphorylation of PPARGC1A protein] CTD PMID:22676303 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of SCD1 mRNA] CTD PMID:29988851 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of SREBF1 mRNA] CTD PMID:29988851 NCBI chr11:60,199,084...60,224,186
Ensembl chr11:60,199,089...60,222,581
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of TGFB1 mRNA] CTD PMID:29988851 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of TNF mRNA] CTD PMID:29988851 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
gonadorelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 (alpha) multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gonadotropin-Releasing Hormone results in decreased expression of ESR1 protein]; Gonadotropin-Releasing Hormone results in increased ubiquitination of and results in increased degradation of and results in decreased expression of ESR1 protein CTD PMID:16055746 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Ube2d2a ubiquitin-conjugating enzyme E2D 2A increases expression EXP Gonadotropin-Releasing Hormone results in increased expression of UBE2D2 mRNA; Gonadotropin-Releasing Hormone results in increased expression of UBE2D2 protein CTD PMID:16055746 NCBI chr18:35,771,559...35,807,172
Ensembl chr18:35,771,558...35,809,494
JBrowse link
Ile(5)-angiotensin II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 increases expression ISO Angiotensin II results in increased expression of AGTR2 mRNA; Angiotensin II results in increased expression of AGTR2 protein CTD PMID:12969123 NCBI chr  X:21,484,624...21,488,833
Ensembl chr  X:21,484,544...21,489,164
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Angiotensin II results in increased expression of EDNRB protein CTD PMID:15007106 NCBI chr14:103,814,615...103,844,508
Ensembl chr14:103,814,625...103,844,402
JBrowse link
insulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insr insulin receptor decreases expression ISO insulin decreases expression of hepatic mRNA in streptozocin treated rats RGD PMID:1280238 RGD:15036814 NCBI chr 8:3,150,922...3,279,649
Ensembl chr 8:3,122,061...3,279,617
JBrowse link
insulin (human) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor increases secretion ISO Novorapid inhibits the reaction [Lipopolysaccharide increases secretion of Tnf protein in serum] RGD PMID:18078960 RGD:15023464 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
neurotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions
increases expression
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Neurotensin results in increased expression of CXCL8 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; [Neurotensin results in increased activity of FOS protein] which results in increased expression of CXCL8 protein; [Neurotensin results in increased activity of FOSL1 protein] which results in increased expression of CXCL8 protein; [Neurotensin results in increased activity of JUNB protein] which results in increased expression of CXCL8 protein; [Neurotensin results in increased activity of NFKB1 protein] which results in increased expression of CXCL8 mRNA; [Neurotensin results in increased activity of RELA protein] which results in increased expression of CXCL8 mRNA; bisindolylmaleimide I inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; bisindolylmaleimide I inhibits the reaction [Neurotensin results in increased expression of CXCL8 protein]; Calcimycin promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; Calcium promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [Neurotensin results in increased expression of CXCL8 protein]; Ionomycin promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; Ro 31-8220 inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; U 0126 inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]
Neurotensin results in increased expression of CXCL8 mRNA; Neurotensin results in increased expression of CXCL8 protein
CTD PMID:17000667 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Fos FBJ osteosarcoma oncogene increases activity
multiple interactions
ISO Neurotensin results in increased activity of FOS protein
[Neurotensin results in increased activity of FOS protein] which results in increased expression of CXCL8 protein
CTD PMID:17000667 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosl1 fos-like antigen 1 increases activity
multiple interactions
ISO Neurotensin results in increased activity of FOSL1 protein
[Neurotensin results in increased activity of FOSL1 protein] which results in increased expression of CXCL8 protein
CTD PMID:17000667 NCBI chr19:5,447,698...5,455,938
Ensembl chr19:5,447,547...5,455,946
JBrowse link
G Junb jun B proto-oncogene multiple interactions
increases activity
ISO [Neurotensin results in increased activity of JUNB protein] which results in increased expression of CXCL8 protein CTD PMID:17000667 NCBI chr 8:84,976,909...84,978,748
Ensembl chr 8:84,974,484...84,978,718
Ensembl chr 8:84,974,484...84,978,718
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 increases activity
multiple interactions
ISO Neurotensin results in increased activity of NFKB1 protein
[Neurotensin results in increased activity of NFKB1 protein] which results in increased expression of CXCL8 mRNA
CTD PMID:17000667 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Ntsr1 neurotensin receptor 1 affects binding ISO Neurotensin binds to NTSR1 protein CTD PMID:19874804 NCBI chr 2:180,499,976...180,544,979
Ensembl chr 2:180,499,976...180,544,980
JBrowse link
G Ntsr2 neurotensin receptor 2 affects binding ISO Neurotensin binds to NTSR2 protein CTD PMID:19874804 NCBI chr12:16,653,443...16,660,236
Ensembl chr12:16,653,382...16,660,227
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases activity
ISO [Neurotensin results in increased activity of RELA protein] which results in increased expression of CXCL8 mRNA CTD PMID:17000667 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
oxytocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Oxytocin results in increased expression of BCL2 protein CTD PMID:23707249 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO Oxytocin results in increased expression of EGFR protein modified form CTD PMID:23707249 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions
ISO Oxytocin results in increased expression of FOS protein
Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein]
CTD PMID:20731630 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO Oxytocin results in increased expression of GDF9 protein CTD PMID:23707249 NCBI chr11:53,430,774...53,437,904
Ensembl chr11:53,431,023...53,437,904
JBrowse link
G Has2 hyaluronan synthase 2 increases expression ISO Oxytocin results in increased expression of HAS2 protein CTD PMID:23707249 NCBI chr15:56,665,627...56,694,546
Ensembl chr15:56,665,627...56,694,539
JBrowse link
G Klf4 Kruppel-like factor 4 (gut) increases expression
multiple interactions
ISO Oxytocin results in increased expression of KLF4 mRNA; Oxytocin results in increased expression of KLF4 protein
KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]]; KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 protein]]; MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein]; MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of KLF4 protein]
CTD PMID:29104011 NCBI chr 4:55,527,137...55,532,475
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 multiple interactions ISO MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein] CTD PMID:29104011 NCBI chr 9:63,163,768...63,381,682
Ensembl chr 9:63,163,768...63,377,902
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases expression ISO Oxytocin results in increased expression of MAPK1 protein modified form CTD PMID:23707249 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases expression ISO Oxytocin results in increased expression of MAPK3 protein modified form CTD PMID:23707249 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mef2a myocyte enhancer factor 2A multiple interactions ISO MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein] CTD PMID:29104011 NCBI chr 7:67,231,163...67,376,456
Ensembl chr 7:67,231,163...67,372,858
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 multiple interactions ISO Oxytocin inhibits the reaction [Cisplatin results in increased expression of MKNK2 mRNA] CTD PMID:21993003 NCBI chr10:80,665,318...80,676,293
Ensembl chr10:80,665,327...80,678,112
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases response to substance ISO MMP2 protein results in decreased susceptibility to Oxytocin CTD PMID:22496348 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases response to substance ISO MMP9 protein results in decreased susceptibility to Oxytocin CTD PMID:22496348 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions ISO Oxytocin inhibits the reaction [Cisplatin results in increased expression of NOXO1 mRNA] CTD PMID:21993003 NCBI chr17:24,696,234...24,700,530
Ensembl chr17:24,696,234...24,700,529
JBrowse link
G Oxtr oxytocin receptor multiple interactions
increases expression
ISO
EXP
Oxytocin analog binds to and results in decreased activity of OXTR protein
Oxytocin results in increased expression of OXTR protein
guizhi-fuling inhibits the reaction [Oxytocin results in increased expression of OXTR protein]
CTD PMID:9502799 PMID:27340106 NCBI chr 6:112,473,683...112,491,035
Ensembl chr 6:112,473,683...112,489,943
JBrowse link
G Plcb1 phospholipase C, beta 1 affects localization EXP Oxytocin affects the localization of PLCB1 protein CTD PMID:11579162 NCBI chr 2:134,786,164...135,475,258
Ensembl chr 2:134,786,067...135,475,258
JBrowse link
G Plcb3 phospholipase C, beta 3 affects localization EXP Oxytocin affects the localization of PLCB3 protein CTD PMID:11579162 NCBI chr19:6,953,708...6,975,006
Ensembl chr19:6,952,325...6,976,470
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO
EXP
Oxytocin results in increased expression of PTGS2 protein
guizhi-fuling inhibits the reaction [Oxytocin results in increased expression of PTGS2 protein]
CTD PMID:23707249 PMID:27340106 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE mRNA]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein] CTD PMID:29104011 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 increases expression ISO Oxytocin results in increased expression of TNFAIP6 protein CTD PMID:23707249 NCBI chr 2:52,038,113...52,056,681
Ensembl chr 2:52,038,009...52,056,686
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 protein]]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 mRNA]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 protein] CTD PMID:29104011 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688
JBrowse link
pasireotide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO pasireotide promotes the reaction [BMP2 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO pasireotide promotes the reaction [BMP4 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO pasireotide promotes the reaction [BMP6 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions ISO pasireotide promotes the reaction [BMP7 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 NCBI chr 2:172,868,012...172,940,321
Ensembl chr 2:172,868,012...172,940,321
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP
ISO
NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP11A1 mRNA]] CTD PMID:23137853 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA] CTD PMID:23137853 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions EXP
ISO
NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP11A1 mRNA]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of HSD3B2 mRNA]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]
pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; pasireotide inhibits the reaction [FSHB protein results in increased abundance of Estradiol]; pasireotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP11A1 mRNA]; pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; pasireotide inhibits the reaction [FSHB protein results in increased expression of HSD3B2 mRNA]; pasireotide inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]
CTD PMID:23137853 NCBI chr 2:107,055,986...107,059,651
Ensembl chr 2:107,056,140...107,059,656
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO
EXP
pasireotide inhibits the reaction [FSHB protein results in increased expression of HSD3B2 mRNA]
NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of HSD3B2 mRNA]]
CTD PMID:23137853 NCBI chr 3:98,711,107...98,724,543
Ensembl chr 3:98,709,255...98,724,543
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein multiple interactions ISO pasireotide promotes the reaction [BMP2 protein results in increased expression of ID1 mRNA]; pasireotide promotes the reaction [BMP4 protein results in increased expression of ID1 mRNA]; pasireotide promotes the reaction [BMP6 protein results in increased expression of ID1 mRNA]; pasireotide promotes the reaction [BMP7 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Nog noggin multiple interactions EXP NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP11A1 mRNA]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of HSD3B2 mRNA]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]] CTD PMID:23137853 NCBI chr11:89,300,638...89,302,559
Ensembl chr11:89,300,638...89,302,332
JBrowse link
G Smad6 SMAD family member 6 decreases expression ISO pasireotide results in decreased expression of SMAD6 mRNA CTD PMID:23137853 NCBI chr 9:63,953,076...64,022,085
Ensembl chr 9:63,953,076...64,022,059
JBrowse link
G Smad7 SMAD family member 7 decreases expression ISO pasireotide results in decreased expression of SMAD7 mRNA CTD PMID:23137853 NCBI chr18:75,367,365...75,395,935
Ensembl chr18:75,367,529...75,395,935
JBrowse link
G Sstr1 somatostatin receptor 1 affects binding ISO pasireotide binds to SSTR1 protein CTD PMID:16625840 NCBI chr12:58,211,421...58,216,037
Ensembl chr12:58,211,772...58,214,444
JBrowse link
G Sstr2 somatostatin receptor 2 affects binding ISO pasireotide binds to SSTR2 protein CTD PMID:16625840 NCBI chr11:113,619,327...113,626,028
Ensembl chr11:113,619,342...113,626,028
JBrowse link
G Sstr3 somatostatin receptor 3 affects binding ISO pasireotide binds to SSTR3 protein CTD PMID:16625840 NCBI chr15:78,537,014...78,549,365
Ensembl chr15:78,537,008...78,544,685
JBrowse link
G Sstr4 somatostatin receptor 4 affects binding ISO pasireotide binds to SSTR4 protein CTD PMID:16625840 NCBI chr 2:148,395,377...148,396,764
Ensembl chr 2:148,395,344...148,396,767
JBrowse link
G Sstr5 somatostatin receptor 5 affects binding ISO pasireotide binds to SSTR5 protein CTD PMID:16625840 NCBI chr17:25,489,875...25,497,288
Ensembl chr17:25,489,875...25,497,288
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP
ISO
NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]] CTD PMID:23137853 NCBI chr 8:25,808,474...25,815,982
Ensembl chr 8:25,806,555...25,815,982
JBrowse link
somatostatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 multiple interactions ISO Somatostatin inhibits the reaction [Dexamethasone results in increased expression of KCNA5 mRNA] CTD PMID:15955845 NCBI chr 6:126,532,551...126,535,555
Ensembl chr 6:126,532,551...126,535,412
JBrowse link
G Sstr1 somatostatin receptor 1 increases expression ISO Somatostatin results in increased expression of SSTR1 mRNA CTD PMID:18575731 NCBI chr12:58,211,421...58,216,037
Ensembl chr12:58,211,772...58,214,444
JBrowse link
G Sstr2 somatostatin receptor 2 increases expression ISO Somatostatin results in increased expression of SSTR2 mRNA CTD PMID:18575731 NCBI chr11:113,619,327...113,626,028
Ensembl chr11:113,619,342...113,626,028
JBrowse link
G Sstr3 somatostatin receptor 3 increases expression ISO Somatostatin results in increased expression of SSTR3 mRNA CTD PMID:18575731 NCBI chr15:78,537,014...78,549,365
Ensembl chr15:78,537,008...78,544,685
JBrowse link
G Sstr4 somatostatin receptor 4 increases expression ISO Somatostatin results in increased expression of SSTR4 mRNA CTD PMID:18575731 NCBI chr 2:148,395,377...148,396,764
Ensembl chr 2:148,395,344...148,396,767
JBrowse link
G Sstr5 somatostatin receptor 5 increases expression ISO Somatostatin results in increased expression of SSTR5 mRNA CTD PMID:18575731 NCBI chr17:25,489,875...25,497,288
Ensembl chr17:25,489,875...25,497,288
JBrowse link
vasopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator increases activity EXP Vasopressins results in increased activity of CFTR protein CTD PMID:15513933 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Mylk myosin, light polypeptide kinase affects response to substance ISO MYLK protein affects the susceptibility to Vasopressins CTD PMID:15347643 NCBI chr16:34,745,199...35,002,436
Ensembl chr16:34,745,210...35,002,420
JBrowse link
vasotocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator increases activity ISO Vasotocin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21791
    role 21770
      biological role 21768
        molecular messenger 18853
          hormone 18306
            peptide hormone 103
              P-factor 0
              [Hyp(3)]-bradykinin 0
              angiotensin + 4
              calcitonin 2
              corticotropin 11
              corticotropin-releasing hormone + 1
              gastrin + 8
              ghrelin 3
              glucagon 24
              gonadorelin 2
              insulin + 2
              kisspeptin-54 0
              neurotensin 8
              oxytocin + 21
              pasireotide 18
              peptide YY 0
              protirelin 0
              sermorelin 0
              somatostatin + 6
              somatostatin-28 0
              tesamorelin 0
              vasopressin + 6
              vasotocin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 21791
    subatomic particle 21777
      composite particle 21777
        hadron 21777
          baryon 21777
            nucleon 21777
              atomic nucleus 21777
                atom 21777
                  main group element atom 21694
                    p-block element atom 21694
                      carbon group element atom 21506
                        carbon atom 21408
                          organic molecular entity 21408
                            organic group 19982
                              organic divalent group 19970
                                organodiyl group 19970
                                  carbonyl group 19963
                                    carbonyl compound 19963
                                      carboxylic acid 19287
                                        carboacyl group 18089
                                          univalent carboacyl group 18089
                                            carbamoyl group 17873
                                              carboxamide 17873
                                                peptide 9558
                                                  peptide hormone 103
                                                    P-factor 0
                                                    [Hyp(3)]-bradykinin 0
                                                    angiotensin + 4
                                                    calcitonin 2
                                                    corticotropin 11
                                                    corticotropin-releasing hormone + 1
                                                    gastrin + 8
                                                    ghrelin 3
                                                    glucagon 24
                                                    gonadorelin 2
                                                    insulin + 2
                                                    kisspeptin-54 0
                                                    neurotensin 8
                                                    oxytocin + 21
                                                    pasireotide 18
                                                    peptide YY 0
                                                    protirelin 0
                                                    sermorelin 0
                                                    somatostatin + 6
                                                    somatostatin-28 0
                                                    tesamorelin 0
                                                    vasopressin + 6
                                                    vasotocin 1
paths to the root