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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pelargonidin
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Accession:CHEBI:25863 term browser browse the term
Definition:An anthocyanidin cation that is flavylium substituted by a hydroxy groups at positions 3, 5, 7 and 4'.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromenylium
 related_synonym: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium;   Formula=C15H11O5;   InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15/h1-7H,(H3-,16,17,18,19)/p+1;   InChIKey=XVFMGWDSJLBXDZ-UHFFFAOYSA-O;   SMILES=Oc1ccc(cc1)-c1[o+]c2cc(O)cc(O)c2cc1O
 xref: Beilstein:1688614;   CAS:134-04-3;   CAS:7690-51-9;   KEGG:C05904;   KNApSAcK:C00007232;   LIPID_MAPS_instance:LMPK12010003
 xref_mesh: MESH:C066957
 xref: PMID:15588587;   PMID:23419638;   Reaxys:1688614;   Wikipedia:Pelargonidin
 cyclic_relationship: is_conjugate_acid_of CHEBI:144777


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pelargonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
ISO pelargonidin metabolite results in increased activity of AHR protein
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin binds to and results in increased activity of AHR protein
CTD PMID:23419638, PMID:23735880 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 protein] CTD PMID:30753810 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO pelargonidin metabolite results in decreased activity of CYP1A1 protein; pelargonidin results in decreased activity of CYP1A1 protein
pelargonidin metabolite results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of CYP1A1 mRNA
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:23419638, PMID:23735880 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO pelargonidin results in increased expression of CYP1A2 mRNA CTD PMID:23419638 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO pelargonidin results in decreased expression of DNMT1 protein CTD PMID:31181187 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO pelargonidin results in decreased expression of DNMT3B protein CTD PMID:31181187 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO pelargonidin results in decreased expression of HDAC1 protein CTD PMID:31181187 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO pelargonidin results in decreased expression of HDAC2 protein CTD PMID:31181187 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO pelargonidin results in decreased expression of HDAC3 protein CTD PMID:31181187 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdac4 histone deacetylase 4 decreases expression ISO pelargonidin results in decreased expression of HDAC4 protein CTD PMID:31181187 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO pelargonidin results in decreased expression of HDAC7 protein CTD PMID:31181187 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO pelargonidin results in increased expression of HMOX1 mRNA; pelargonidin results in increased expression of HMOX1 protein CTD PMID:31181187 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] CTD PMID:30753810 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:30753810 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:30753810 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:30753810 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases methylation
affects response to substance
ISO pelargonidin results in decreased methylation of NFE2L2 promoter
NFE2L2 protein affects the susceptibility to pelargonidin
CTD PMID:31181187 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18274639 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO pelargonidin results in increased expression of NQO1 mRNA; pelargonidin results in increased expression of NQO1 protein CTD PMID:31181187 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein]
CTD PMID:18274639, PMID:30753810 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:30753810 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
CTD PMID:18720166, PMID:30753810 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP pelargonidin results in decreased activity of TXNRD1 protein modified form CTD PMID:16618767 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:30753810 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
pelargonidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
pelargonidin 3-O-beta-D-glucoside chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            eukaryotic metabolite 18906
              plant metabolite 17359
                pelargonidin 27
                  4'''-demalonylsalvianin 0
                  monardaein 0
                  pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside 0
                  pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) 0
                  pelargonidin 3-O-beta-D-glucoside + 2
                  pelargonidin 3-O-beta-D-sambubioside 0
                  pelargonidin 3-O-sophoroside 0
                  pelargonidin chloride 0
                  pelargonin 0
                  salvianin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  oxacycle 17181
                                    benzopyran 10132
                                      1-benzopyran 9848
                                        chromenes 931
                                          chromene 153
                                            2H-chromene 153
                                              chromenyliums 153
                                                chromenylium 153
                                                  flavylium 153
                                                    anthocyanidin cation 153
                                                      5-hydroxyanthocyanidin 103
                                                        pelargonidin 27
                                                          4'''-demalonylsalvianin 0
                                                          monardaein 0
                                                          pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside 0
                                                          pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) 0
                                                          pelargonidin 3-O-beta-D-glucoside + 2
                                                          pelargonidin 3-O-beta-D-sambubioside 0
                                                          pelargonidin 3-O-sophoroside 0
                                                          pelargonidin chloride 0
                                                          pelargonin 0
                                                          salvianin 0
paths to the root

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