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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:p-menthane
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Accession:CHEBI:25826 term browser browse the term
Definition:A monoterpene that has formula C10H20.
Synonyms:related_synonym: 1-Methyl-4-(propan-2-yl)cyclohexane;   1-isopropyl-4-methylcyclohexane;   1-methyl-4-(1-methylethyl)-cyclohexane;   Formula=C10H20;   InChI=1S/C10H20/c1-8(2)10-6-4-9(3)5-7-10/h8-10H,4-7H2,1-3H3;   InChIKey=CFJYNSNXFXLKNS-UHFFFAOYSA-N;   SMILES=CC1CCC(CC1)C(C)C;   p-Menthan;   para-menthane
 xref: Beilstein:1900617;   CAS:99-82-1;   LIPID_MAPS_instance:LMPR0102090000



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(S)-(-)-perillyl alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 increases expression ISO perillyl alcohol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of BAX protein] CTD PMID:19161993 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein] CTD PMID:19161993 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cat catalase multiple interactions ISO
EXP
perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
perillyl alcohol inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD PMID:19161993 PMID:20923693 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO perillyl alcohol results in decreased expression of CCNA2 protein CTD PMID:17138864 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO perillyl alcohol results in decreased expression of CCNB1 protein CTD PMID:17138864 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
ISO perillyl alcohol results in decreased expression of CDK2 protein
perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; perillyl alcohol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases response to substance
multiple interactions
increases expression
ISO CDKN1A protein results in increased susceptibility to perillyl alcohol
perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
perillyl alcohol results in increased expression of CDKN1A protein
CTD PMID:17138864 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
increases response to substance
multiple interactions
ISO perillyl alcohol results in increased expression of CDKN1B protein
CDKN1B protein results in increased susceptibility to perillyl alcohol
perillyl alcohol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO perillyl alcohol results in increased expression of FBXO32 mRNA; perillyl alcohol results in increased expression of FBXO32 protein CTD PMID:19406843 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha multiple interactions EXP [Vitamin A co-treated with perillyl alcohol] results in decreased expression of FNTA protein CTD PMID:15959631 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta multiple interactions
increases expression
decreases expression
EXP [perillyl alcohol co-treated with Vitamin A] results in decreased expression of FNTB mRNA
perillyl alcohol results in increased expression of FNTB protein
perillyl alcohol results in decreased expression of FNTB mRNA
CTD PMID:15959631 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]
perillyl alcohol inhibits the reaction [Ethanol results in decreased activity of GSR protein]
CTD PMID:19161993 PMID:20923693 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions EXP perillyl alcohol inhibits the reaction [Ethanol results in decreased activity of H6PD protein] CTD PMID:20923693 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Ivl involucrin decreases expression ISO perillyl alcohol results in decreased expression of IVL protein CTD PMID:10769631 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] CTD PMID:19161993 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:19161993 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] CTD PMID:19161993 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein] CTD PMID:19161993 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions
increases expression
ISO Mevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RAP1A protein] CTD PMID:12671036 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP perillyl alcohol inhibits the reaction [Ethanol results in increased activity of RELA protein] CTD PMID:20923693 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression
ISO
EXP
Mevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RHOA protein]
[perillyl alcohol co-treated with Vitamin A] results in increased expression of RHOA mRNA
CTD PMID:12671036 PMID:15959631 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B multiple interactions
increases expression
ISO
EXP
Mevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RHOB protein]
perillyl alcohol results in increased expression of RHOB mRNA; perillyl alcohol results in increased expression of RHOB protein
[perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB mRNA; [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB protein
CTD PMID:12671036 PMID:15959631 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP perillyl alcohol inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:20923693 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
1,8-cineole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of ACTR2 protein] CTD PMID:31483951 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of CDC42 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of CDC42 protein] CTD PMID:31483951 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Eucalyptol results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cttn cortactin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of CTTN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of CTTN protein] CTD PMID:31483951 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Eucalyptol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases hydroxylation
multiple interactions
ISO CYP3A4 protein results in increased hydroxylation of Eucalyptol
Eucalyptol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]
CTD PMID:15715982 PMID:18385293 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases hydroxylation ISO CYP3A5 protein results in increased hydroxylation of Eucalyptol CTD PMID:15715982 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ezr ezrin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of EZR protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of EZR protein] CTD PMID:31483951 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Eucalyptol results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]; RHOA protein inhibits the reaction [Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]] CTD PMID:31483951 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Eucalyptol results in decreased expression of HMGCR protein CTD PMID:24613879 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ICAM1 mRNA]; Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ICAM1 protein] CTD PMID:29789401 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 protein] CTD PMID:29789401 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lep leptin multiple interactions ISO Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of CTTN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of EZR protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PTK2 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PXN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SRC protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SYNPO protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of TLN1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of VCL protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased abundance of Blood Glucose]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of CDC42 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of PXN protein modified form]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RAC1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RHOA protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of ROCK1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of VCL protein modified form] CTD PMID:31483951 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK8 protein] CTD PMID:23872422 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK9 protein] CTD PMID:23872422 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Muc19 mucin 19 decreases expression ISO Eucalyptol results in decreased expression of MUC19 mRNA CTD PMID:26207629 NCBI chr 7:123,017,896...123,139,053 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides results in increased expression of MUC2 mRNA] CTD PMID:26207629 NCBI chr 1:196,796,257...196,831,740 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MUC5AC mRNA]; Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MUC5AC protein] CTD PMID:29215731 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides affects the expression of NFKBIA protein]; Eucalyptol inhibits the reaction [Lipopolysaccharides inhibits the reaction [RELA protein binds to NFKBIA protein]] CTD PMID:23872422 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of PTK2 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PTK2 protein] CTD PMID:31483951 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pxn paxillin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein]; Eucalyptol inhibits the reaction [Glucose results in increased expression of PXN protein modified form]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PXN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of PXN protein modified form]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein]] CTD PMID:31483951 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of RAC1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RAC1 protein] CTD PMID:31483951 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides inhibits the reaction [RELA protein binds to NFKBIA protein]] CTD PMID:23872422 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of RHOA protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RHOA protein]; RHOA protein inhibits the reaction [Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein]]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of VCL protein]] CTD PMID:31483951 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of ROCK1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of ROCK1 protein] CTD PMID:31483951 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Eucalyptol inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of SRC protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SRC protein] CTD PMID:31483951 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Synpo synaptopodin multiple interactions ISO Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SYNPO protein] CTD PMID:31483951 NCBI chr18:54,048,299...54,106,388
Ensembl chr18:54,026,152...54,102,126
JBrowse link
G Tln1 talin 1 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of TLN1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of TLN1 protein] CTD PMID:31483951 NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNF protein]
Eucalyptol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:23872422 PMID:26207629 PMID:29789401 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcl vinculin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of VCL protein]; Eucalyptol inhibits the reaction [Glucose results in increased expression of VCL protein modified form]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of VCL protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of VCL protein modified form]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of VCL protein]] CTD PMID:31483951 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
4-terpineol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D increases expression
multiple interactions
ISO terpinenol-4 results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of CTSD mRNA]
CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO terpinenol-4 inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO terpinenol-4 results in increased activity of ESR1 protein
NCOA2 protein promotes the reaction [terpinenol-4 results in increased activity of ESR1 protein]
CTD PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions
ISO terpinenol-4 results in increased expression of GREB1 mRNA
Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of GREB1 mRNA]
CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [terpinenol-4 results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of PGR mRNA] CTD PMID:31393563 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 multiple interactions ISO terpinenol-4 inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO terpinenol-4 inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of terpinenol-4 CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link
alpha-terpineol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D increases expression ISO alpha-terpineol results in increased expression of CTSD mRNA CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO alpha-terpineol binds to and results in increased activity of ESR1 protein; NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:27633901 PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [alpha-terpineol results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of alpha-terpineol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link
ascaridole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor affects response to substance ISO ERCC6 protein affects the susceptibility to ascaridole CTD PMID:22280988 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor affects response to substance ISO XPC protein affects the susceptibility to ascaridole CTD PMID:22280988 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
carvacrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
EXP [propiconazole co-treated with carvacrol] results in decreased activity of ACHE protein
carvacrol results in decreased activity of ACHE protein
CTD PMID:29852196 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP carvacrol inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]; carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]] CTD PMID:29071762 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; carvacrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
carvacrol results in increased activity of AHR protein
CTD PMID:29191726 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
carvacrol results in increased activity of CASP3 protein
carvacrol inhibits the reaction [Poloxamer results in increased expression of CASP3 protein]; carvacrol inhibits the reaction [propiconazole results in increased expression of CASP3 protein]; carvacrol inhibits the reaction [Simvastatin promotes the reaction [Poloxamer results in increased expression of CASP3 protein]]
CTD PMID:23146755 PMID:29071762 PMID:29852196 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP carvacrol inhibits the reaction [Poloxamer results in decreased activity of CAT protein]; carvacrol inhibits the reaction [propiconazole results in decreased activity of CAT protein]; carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased activity of CAT protein]] CTD PMID:29071762 PMID:29852196 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP carvacrol inhibits the reaction [Poloxamer results in increased secretion of CKM protein]; carvacrol inhibits the reaction [Simvastatin results in increased secretion of CKM protein] CTD PMID:29071762 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased expression of CXCL1 protein]]; carvacrol inhibits the reaction [irinotecan results in increased expression of CXCL1 protein] CTD PMID:27838229 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO carvacrol results in increased expression of CYP1A1 mRNA
carvacrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:29191726 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation
multiple interactions
ISO carvacrol results in increased phosphorylation of EGFR protein
KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of EGFR protein]
CTD PMID:32535744 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP carvacrol inhibits the reaction [propiconazole results in increased expression of GFAP protein] CTD PMID:29852196 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A increases activity ISO carvacrol results in increased activity of HTR3A protein CTD PMID:26456648 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased expression of IL1B protein]]; carvacrol inhibits the reaction [irinotecan results in increased expression of IL1B protein] CTD PMID:27838229 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Lep leptin multiple interactions EXP carvacrol inhibits the reaction [Poloxamer results in increased secretion of LEP protein] CTD PMID:29071762 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mb myoglobin multiple interactions EXP carvacrol inhibits the reaction [Poloxamer results in increased secretion of MB protein] CTD PMID:29071762 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased activity of MPO protein]]; carvacrol inhibits the reaction [irinotecan results in increased activity of MPO protein] CTD PMID:27838229 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO carvacrol inhibits the reaction [irinotecan results in increased expression of NFKB1 protein] CTD PMID:27838229 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions
increases phosphorylation
ISO Erlotinib Hydrochloride inhibits the reaction [carvacrol results in increased phosphorylation of PIK3CA protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of PIK3CA protein] CTD PMID:32535744 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
carvacrol inhibits the reaction [irinotecan results in increased expression of PTGS2 protein]
carvacrol inhibits the reaction [propiconazole results in increased expression of PTGS2 protein]
CTD PMID:27838229 PMID:29852196 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
ISO Erlotinib Hydrochloride inhibits the reaction [carvacrol results in increased phosphorylation of RELA protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of RELA protein] CTD PMID:32535744 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tgfa transforming growth factor alpha increases secretion
multiple interactions
ISO carvacrol results in increased secretion of TGFA protein
KN 93 inhibits the reaction [carvacrol results in increased secretion of TGFA protein]
CTD PMID:32535744 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased expression of TNF protein]]; carvacrol inhibits the reaction [irinotecan results in increased expression of TNF protein] CTD PMID:27838229 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity EXP
ISO
carvacrol results in increased activity of TRPA1 protein CTD PMID:16617338 PMID:22935519 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity
affects response to substance
multiple interactions
increases response to substance
ISO
EXP
carvacrol results in increased activity of TRPV3 protein
TRPV3 protein affects the susceptibility to carvacrol
TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of EGFR protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of PIK3CA protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of RELA protein]
TRPV3 protein results in increased susceptibility to carvacrol
[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; carvacrol binds to and results in increased activity of TRPV3 protein; Ruthenium Red inhibits the reaction [[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium]
CTD PMID:16617338 PMID:20086034 PMID:29658714 PMID:32535744 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
carveol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhob ras homolog family member B increases expression
multiple interactions
ISO carveol results in increased expression of RHOB protein
Mevalonic Acid affects the reaction [carveol results in increased expression of RHOB protein]
CTD PMID:12671036 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of carveol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link
carvone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO [carvone co-treated with limonene] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; carvone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:29191726 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO carvone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
carvone results in increased expression of CYP1A1 mRNA
CTD PMID:29191726 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gna15 G protein subunit alpha 15 multiple interactions
increases response to substance
ISO [GNA15 protein results in increased susceptibility to carvone] which results in increased activity of OLFR50 protein CTD PMID:9875846 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression
increases secretion
ISO carvone results in increased expression of GNRH1 mRNA
carvone results in increased secretion of GNRH1 protein
CTD PMID:10566683 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Por cytochrome p450 oxidoreductase increases response to substance ISO POR protein results in increased susceptibility to carvone analog CTD PMID:21376747 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Rhoa ras homolog family member A increases expression
multiple interactions
ISO carvone results in increased expression of RHOA protein
Mevalonic Acid affects the reaction [carvone results in increased expression of RHOA protein]
CTD PMID:12671036 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B multiple interactions
increases expression
ISO Mevalonic Acid affects the reaction [carvone results in increased expression of RHOB protein] CTD PMID:12671036 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
limonene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP limonene inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:29251412 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [carvone co-treated with limonene] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:29191726 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 decreases expression EXP limonene results in decreased expression of AKR1D1 mRNA CTD PMID:12815608 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Alb albumin increases expression
multiple interactions
EXP limonene results in increased expression of ALB protein
limonene inhibits the reaction [Carbon Tetrachloride results in decreased secretion of ALB protein]
CTD PMID:23159986 PMID:29251412 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Arg1 arginase 1 increases expression EXP limonene results in increased expression of ARG1 mRNA CTD PMID:12815608 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO limonene results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP limonene results in increased expression of ATP1A1 mRNA CTD PMID:12815608 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO limonene results in decreased expression of BCL2 protein CTD PMID:12921557 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Calm1 calmodulin 1 increases expression EXP limonene results in increased expression of CALM1 mRNA CTD PMID:12815608 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Cat catalase multiple interactions EXP limonene inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:29251412 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccng1 cyclin G1 increases expression EXP limonene results in increased expression of CCNG1 mRNA CTD PMID:12815608 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP limonene results in increased expression of CDK1 mRNA CTD PMID:12815608 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP limonene results in increased expression of COL3A1 mRNA CTD PMID:12815608 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression EXP limonene results in increased expression of COX4I1 mRNA CTD PMID:12815608 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression EXP limonene results in increased expression of COX5A mRNA CTD PMID:12815608 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression EXP limonene results in decreased expression of COX6C mRNA CTD PMID:12815608 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Limonene results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyb5a cytochrome b5 type A increases expression EXP limonene results in increased expression of CYB5A mRNA CTD PMID:12815608 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cycs cytochrome c, somatic increases expression EXP limonene results in increased expression of CYCS mRNA CTD PMID:12815608 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO limonene results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP limonene results in decreased activity of CYP2B1 protein CTD PMID:9242356 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 increases expression EXP limonene results in increased expression of CYP2B12 mRNA CTD PMID:12815608 NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO Limonene inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam] CTD PMID:18385293 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO Limonene inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP limonene results in increased expression of CYP51 mRNA CTD PMID:12815608 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP limonene results in increased expression of DECR1 mRNA CTD PMID:12815608 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 increases expression EXP limonene results in increased expression of DNAJA2 mRNA CTD PMID:12815608 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP limonene results in increased expression of DUT mRNA CTD PMID:12815608 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP limonene results in increased expression of GADD45A mRNA CTD PMID:12815608 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO limonene results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP limonene results in increased expression of GJB2 mRNA CTD PMID:12815608 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO limonene inhibits the reaction [Pyruvaldehyde results in decreased activity of GLO1 protein] CTD PMID:28986142 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions
ISO GNA15 protein results in increased susceptibility to limonene
[GNA15 protein results in increased susceptibility to limonene] which results in increased activity of OLFR56 protein
CTD PMID:9875846 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP limonene results in increased expression of GPX1 mRNA CTD PMID:12815608 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP limonene results in increased expression of GPX4 mRNA CTD PMID:12815608 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Limonene results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP limonene results in increased expression of GRPEL1 mRNA CTD PMID:12815608 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP limonene results in increased expression of GSTM1 protein CTD PMID:23159986 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression EXP limonene results in increased expression of GSTM5 mRNA CTD PMID:12815608 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO limonene results in increased expression of HMOX1 mRNA
limonene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 protein]
CTD PMID:20491607 PMID:28986142 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO limonene inhibits the reaction [HRAS protein results in increased susceptibility to Methylnitrosourea] CTD PMID:11802805 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression EXP limonene results in increased expression of HSP90AB1 mRNA CTD PMID:12815608 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP limonene results in increased expression of HSPD1 mRNA CTD PMID:12815608 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il1a interleukin 1 alpha affects expression ISO Limonene affects the expression of IL1A protein CTD PMID:19878710 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il6 interleukin 6 multiple interactions ISO limonene inhibits the reaction [Pyruvaldehyde results in increased secretion of IL6 protein] CTD PMID:28986142 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO limonene inhibits the reaction [Diethylnitrosamine results in increased expression of JUN protein] CTD PMID:10425313 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lif LIF, interleukin 6 family cytokine affects expression ISO Limonene affects the expression of LIF protein CTD PMID:19878710 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression EXP limonene results in increased expression of MAPK14 mRNA CTD PMID:12815608 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP limonene results in increased expression of MAPK6 mRNA CTD PMID:12815608 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression EXP limonene results in increased expression of MGAT2 mRNA CTD PMID:12815608 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO
EXP
limonene inhibits the reaction [Diethylnitrosamine results in increased expression of MYC protein]
limonene results in increased expression of MYC mRNA
CTD PMID:10425313 PMID:12815608 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression EXP limonene results in increased expression of NFKB1 mRNA CTD PMID:12815608 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Npy neuropeptide Y decreases expression ISO
EXP
limonene results in decreased expression of NPY protein
limonene results in decreased expression of NPY mRNA
CTD PMID:22757684 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects binding
increases expression
EXP limonene binds to OBP3 protein
limonene results in increased expression of OBP3 protein
CTD PMID:19428932 PMID:20069279 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G Olr1386 olfactory receptor 1386 multiple interactions
increases activity
ISO [GNA15 protein results in increased susceptibility to limonene] which results in increased activity of OLFR56 protein
limonene results in increased activity of OLFR56 protein
CTD PMID:9875846 NCBI chr10:33,399,891...33,404,298
Ensembl chr10:33,398,913...33,404,401
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP limonene results in increased expression of PCNA mRNA CTD PMID:12815608 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression EXP limonene results in increased expression of PDIA3 mRNA CTD PMID:12815608 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Limonene results in increased expression of PGR mRNA] CTD PMID:31393563 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [limonene co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein CTD PMID:28986142 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP limonene results in increased expression of PPIA mRNA CTD PMID:12815608 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppib peptidylprolyl isomerase B increases expression EXP limonene results in increased expression of PPIB mRNA CTD PMID:12815608 NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression EXP limonene results in decreased expression of RARA mRNA CTD PMID:12815608 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP limonene inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein] CTD PMID:29251412 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP limonene results in increased expression of SCD1 mRNA CTD PMID:12815608 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 multiple interactions ISO limonene inhibits the reaction [2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate results in increased activity of SCN5A protein] CTD PMID:29306026 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Limonene inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP limonene results in decreased expression of SOD1 mRNA CTD PMID:12815608 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP limonene results in increased expression of TGFA mRNA CTD PMID:12815608 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP limonene inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:29251412 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
limonene inhibits the reaction [Pyruvaldehyde results in increased secretion of TNF protein]
limonene inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
CTD PMID:28986142 PMID:29251412 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO limonene results in increased expression of TP53 protein CTD PMID:12921557 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vip vasoactive intestinal peptide increases expression EXP limonene results in increased expression of VIP protein CTD PMID:20934418 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
menthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
p-menth-4(8)-en-3-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor increases expression EXP pulegone results in increased expression of TNF mRNA CTD PMID:15135310 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
p-menthan-3-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor increases expression ISO Menthol results in increased expression of DED mRNA CTD PMID:26760959 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Aatk apoptosis-associated tyrosine kinase decreases expression ISO Menthol results in decreased expression of AATK mRNA CTD PMID:26760959 NCBI chr10:105,290,750...105,327,219
Ensembl chr10:105,291,585...105,327,112
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Menthol results in increased expression of ABCC2 mRNA CTD PMID:24594507 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Menthol results in increased expression of ABCC3 mRNA CTD PMID:24594507 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Actb actin, beta decreases expression ISO Menthol results in decreased expression of ACTB protein CTD PMID:26760959 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression ISO Menthol results in increased expression of ADAM17 mRNA CTD PMID:26760959 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Agtr2 angiotensin II receptor, type 2 decreases expression ISO Menthol results in decreased expression of AGTR2 mRNA CTD PMID:26760959 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO Menthol results in increased expression of AIF1 mRNA CTD PMID:26760959 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO Menthol results in decreased expression of AIFM1 mRNA CTD PMID:26760959 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO Menthol results in decreased expression of AKT1 mRNA CTD PMID:26760959 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO Menthol results in decreased expression of AKT2 mRNA CTD PMID:26760959 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 increases expression ISO Menthol results in increased expression of AKT3 mRNA CTD PMID:26760959 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Anxa5 annexin A5 increases expression ISO Menthol results in increased expression of ANXA5 protein CTD PMID:26760959 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Menthol results in increased expression of APAF1 mRNA CTD PMID:26760959 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression ISO Menthol results in decreased expression of APC mRNA CTD PMID:26760959 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in decreased expression of and results in decreased secretion of APOA1 protein CTD PMID:27818348 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G App amyloid beta precursor protein decreases expression ISO Menthol results in decreased expression of APP mRNA CTD PMID:26760959 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arid4a AT-rich interaction domain 4A increases expression ISO Menthol results in increased expression of ARID4A mRNA CTD PMID:26760959 NCBI chr 6:89,522,463...89,593,868
Ensembl chr 6:89,522,442...89,593,510
JBrowse link
G Atg5 autophagy related 5 increases expression ISO Menthol results in increased expression of ATG5 mRNA CTD PMID:26760959 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO Menthol results in decreased expression of ATM mRNA CTD PMID:26760959 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Menthol results in increased expression of ATP2A3 mRNA CTD PMID:26760959 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 decreases expression ISO Menthol results in decreased expression of BRE mRNA CTD PMID:26760959 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Menthol results in increased expression of BAD mRNA CTD PMID:26760959 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO Menthol results in decreased expression of BAG1 mRNA CTD PMID:26760959 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag2 BAG cochaperone 2 decreases expression ISO Menthol results in decreased expression of BAG2 mRNA CTD PMID:26760959 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO Menthol results in increased expression of BAG3 mRNA CTD PMID:26760959 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bag4 BAG cochaperone 4 increases expression ISO Menthol results in increased expression of BAG4 mRNA CTD PMID:26760959 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Bag5 BAG cochaperone 5 increases expression ISO Menthol results in increased expression of BAG5 mRNA CTD PMID:26760959 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Menthol results in increased expression of BAK1 mRNA CTD PMID:26760959 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO Menthol results in decreased expression of BAX mRNA CTD PMID:26760959 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl10 BCL10, immune signaling adaptor decreases expression ISO Menthol results in decreased expression of BCL10 mRNA CTD PMID:26760959 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Menthol results in decreased expression of BCL2 mRNA CTD PMID:26760959 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l10 BCL2 like 10 increases expression ISO Menthol results in increased expression of BCL2L10 mRNA CTD PMID:26760959 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l12 BCL2 like 12 decreases expression ISO Menthol results in decreased expression of BCL2L12 mRNA CTD PMID:26760959 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Bcl2l14 BCL2 like 14 increases expression ISO Menthol results in increased expression of BCL2L14 mRNA CTD PMID:26760959 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO Menthol results in increased expression of BCL2L2 mRNA CTD PMID:26760959 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Menthol results in increased expression of BCL3 mRNA CTD PMID:26760959 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl7b BAF chromatin remodeling complex subunit BCL7B increases expression ISO Menthol results in increased expression of BCL7B mRNA CTD PMID:26760959 NCBI chr12:21,496,856...21,510,202
Ensembl chr12:21,496,856...21,510,202
JBrowse link
G Becn1 beclin 1 increases expression ISO Menthol results in increased expression of BECN1 mRNA CTD PMID:26760959 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bex3 brain expressed X-linked 3 increases expression ISO Menthol results in increased expression of BEX3 mRNA CTD PMID:26760959 NCBI chr  X:99,273,238...99,274,799
Ensembl chr  X:99,273,161...99,274,800
JBrowse link
G Bfar bifunctional apoptosis regulator decreases expression ISO Menthol results in decreased expression of BFAR mRNA CTD PMID:26760959 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Menthol results in increased expression of BID mRNA CTD PMID:26760959 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer increases expression ISO Menthol results in increased expression of BIK mRNA CTD PMID:26760959 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Menthol results in decreased expression of BIRC3 mRNA CTD PMID:26760959 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase decreases expression ISO Menthol results in decreased expression of BLK mRNA CTD PMID:26760959 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO Menthol results in decreased expression of BMF mRNA CTD PMID:26760959 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression ISO Menthol results in increased expression of BNIP2 mRNA CTD PMID:26760959 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Menthol results in decreased expression of BNIP3 mRNA CTD PMID:26760959 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO Menthol results in decreased expression of BNIP3L mRNA CTD PMID:26760959 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Bok BCL2 family apoptosis regulator BOK decreases expression ISO Menthol results in decreased expression of BOK mRNA CTD PMID:26760959 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B decreases expression ISO Menthol results in decreased expression of CACNA1B mRNA CTD PMID:26760959 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D decreases expression ISO Menthol results in decreased expression of CACNA1D mRNA CTD PMID:26760959 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E decreases expression ISO Menthol results in decreased expression of CACNA1E mRNA CTD PMID:26760959 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F increases expression ISO Menthol results in increased expression of CACNA1F mRNA CTD PMID:26760959 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G increases expression ISO Menthol results in increased expression of CACNA1G mRNA CTD PMID:26760959 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H decreases expression ISO Menthol results in decreased expression of CACNA1H mRNA CTD PMID:26760959 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 decreases expression ISO Menthol results in decreased expression of CACNA2D2 mRNA CTD PMID:26760959 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 decreases expression ISO Menthol results in decreased expression of CACNB1 mRNA CTD PMID:26760959 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 decreases expression ISO Menthol results in decreased expression of CACNB2 mRNA CTD PMID:26760959 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 decreases expression ISO Menthol results in decreased expression of CACNB4 mRNA CTD PMID:26760959 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Capn1 calpain 1 increases expression ISO Menthol results in increased expression of CAPN1 mRNA CTD PMID:26760959 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Capn11 calpain 11 decreases expression ISO Menthol results in decreased expression of CAPN11 mRNA CTD PMID:26760959 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
JBrowse link
G Capn6 calpain 6 decreases expression ISO Menthol results in decreased expression of CAPN6 mRNA CTD PMID:26760959 NCBI chr  X:107,380,774...107,405,489
Ensembl chr  X:107,380,774...107,405,489
JBrowse link
G Capn9 calpain 9 decreases expression ISO Menthol results in decreased expression of CAPN9 mRNA CTD PMID:26760959 NCBI chr19:52,549,448...52,586,413
Ensembl chr19:52,549,448...52,586,413
JBrowse link
G Card10 caspase recruitment domain family, member 10 decreases expression ISO Menthol results in decreased expression of CARD10 mRNA CTD PMID:26760959 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO Menthol results in decreased expression of CARD11 mRNA CTD PMID:26760959 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Card14 caspase recruitment domain family, member 14 decreases expression ISO Menthol results in decreased expression of CARD14 mRNA CTD PMID:26760959 NCBI chr10:104,572,059...104,601,606
Ensembl chr10:104,566,424...104,601,905
JBrowse link
G Card6 caspase recruitment domain family, member 6 decreases expression ISO Menthol results in decreased expression of CARD6 mRNA CTD PMID:26760959 NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846
JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression ISO Menthol results in increased expression of CARD9 mRNA CTD PMID:26760959 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Casp1 caspase 1 decreases expression ISO Menthol results in decreased expression of CASP1 mRNA CTD PMID:26760959 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp14 caspase 14 increases expression ISO Menthol results in increased expression of CASP14 mRNA CTD PMID:26760959 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Casp2 caspase 2 decreases expression ISO Menthol results in decreased expression of CASP2 mRNA CTD PMID:26760959 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO Menthol results in increased activity of CASP3 protein
Menthol results in increased expression of CASP3 mRNA
CTD PMID:21472860 PMID:26760959 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO Menthol results in increased expression of CASP4 mRNA CTD PMID:26760959 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 decreases expression ISO Menthol results in decreased expression of CASP6 mRNA CTD PMID:26760959 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases expression ISO Menthol results in increased expression of CASP7 mRNA CTD PMID:26760959 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 decreases expression ISO Menthol results in decreased expression of CASP8 mRNA CTD PMID:26760959 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 decreases expression ISO Menthol results in decreased expression of CASP8AP2 mRNA CTD PMID:26760959 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Casp9 caspase 9 increases expression ISO Menthol results in increased expression of CASP9 mRNA CTD PMID:26760959 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cav1 caveolin 1 increases expression ISO Menthol results in increased expression of CAV1 mRNA CTD PMID:26760959 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbl Cbl proto-oncogene decreases expression ISO Menthol results in decreased expression of CBL mRNA CTD PMID:26760959 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO Menthol results in decreased expression of CBLB mRNA CTD PMID:26760959 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cbx4 chromobox 4 increases expression ISO Menthol results in increased expression of CBX4 mRNA CTD PMID:26760959 NCBI chr10:104,337,140...104,343,210 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Menthol results in decreased expression of CCND1 mRNA CTD PMID:26760959 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccng1 cyclin G1 decreases expression ISO Menthol results in decreased expression of CCNG1 mRNA CTD PMID:26760959 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 decreases expression ISO Menthol results in decreased expression of CCT2 protein CTD PMID:26760959 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cd27 CD27 molecule increases expression ISO Menthol results in increased expression of CD27 mRNA CTD PMID:26760959 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd40 CD40 molecule decreases expression ISO Menthol results in decreased expression of CD40 mRNA CTD PMID:26760959 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Menthol results in decreased expression of CD40LG mRNA CTD PMID:26760959 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd70 Cd70 molecule increases expression ISO Menthol results in increased expression of CD70 mRNA CTD PMID:26760959 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Menthol results in increased expression of CDH1 mRNA CTD PMID:26760959 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh3 cadherin 3 increases expression ISO Menthol results in increased expression of CDH3 mRNA CTD PMID:26760959 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdk13 cyclin-dependent kinase 13 increases expression ISO Menthol results in increased expression of CDK13 mRNA CTD PMID:26760959 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 increases expression ISO Menthol results in increased expression of CDK5R2 mRNA CTD PMID:26760959 NCBI chr 9:76,416,251...76,417,719
Ensembl chr 9:76,416,062...76,418,344
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO Menthol results in decreased expression of CDKN1A mRNA CTD PMID:26760959 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Menthol results in increased expression of CDKN2A mRNA CTD PMID:26760959 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression ISO Menthol results in decreased expression of CDKN2D mRNA CTD PMID:26760959 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression ISO Menthol results in increased expression of CELF2 mRNA CTD PMID:26760959 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Menthol results in increased expression of CFLAR mRNA CTD PMID:26760959 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of CHI3L1 protein CTD PMID:27818348 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression ISO Menthol results in increased expression of CIDEA mRNA CTD PMID:26760959 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cideb cell death-inducing DFFA-like effector b increases expression ISO Menthol results in increased expression of CIDEB mRNA CTD PMID:26760959 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Clu clusterin decreases expression ISO Menthol results in decreased expression of CLU mRNA CTD PMID:26760959 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression ISO Menthol results in decreased expression of CNR1 mRNA CTD PMID:26760959 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 decreases expression ISO Menthol results in decreased expression of CNR2 mRNA CTD PMID:26760959 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Crp C-reactive protein multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of CRP protein CTD PMID:27818348 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cse1l chromosome segregation 1 like increases expression ISO Menthol results in increased expression of CSE1L mRNA CTD PMID:26760959 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO Menthol results in decreased expression of CTNNB1 mRNA CTD PMID:26760959 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in decreased expression of and results in decreased secretion of CXCL2 protein CTD PMID:27818348 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of CXCL6 protein CTD PMID:27818348 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cyc1 cytochrome c-1 decreases expression ISO Menthol results in decreased expression of CYC1 mRNA CTD PMID:26760959 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO Menthol results in increased expression of CYP2B10 mRNA CTD PMID:24594507 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Menthol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO Menthol results in increased expression of CYP2C29 mRNA CTD PMID:24594507
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Menthol results in increased expression of CYP3A4 mRNA CTD PMID:24594507 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dad1 defender against cell death 1 decreases expression ISO Menthol results in decreased expression of DAD1 mRNA CTD PMID:26760959 NCBI chr15:27,677,285...27,697,275
Ensembl chr15:27,677,268...27,697,347
JBrowse link
G Dap death-associated protein decreases expression ISO Menthol results in decreased expression of DAP mRNA CTD PMID:26760959 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dap3 death associated protein 3 decreases expression ISO Menthol results in decreased expression of DAP3 mRNA CTD PMID:26760959 NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO Menthol results in decreased expression of DAPK1 mRNA CTD PMID:26760959 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dapk2 death-associated protein kinase 2 decreases expression ISO Menthol results in decreased expression of DAPK2 mRNA CTD PMID:26760959 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
JBrowse link
G Dapk3 death-associated protein kinase 3 decreases expression ISO Menthol results in decreased expression of DAPK3 mRNA CTD PMID:26760959 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Daxx death-domain associated protein decreases expression ISO Menthol results in decreased expression of DAXX mRNA CTD PMID:26760959 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ddx41 DEAD-box helicase 41 increases expression ISO Menthol results in increased expression of ABS mRNA CTD PMID:26760959 NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415
JBrowse link
G Defb4 defensin beta 4 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of DEFB4 protein CTD PMID:27818348 NCBI chr16:70,650,472...70,653,665
Ensembl chr16:70,650,472...70,653,665
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases expression ISO Menthol results in increased expression of DFFA mRNA CTD PMID:26760959 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Dffb DNA fragmentation factor subunit beta increases expression ISO Menthol results in increased expression of DFFB mRNA CTD PMID:26760959 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO Menthol results in increased expression of DIABLO mRNA CTD PMID:26760959 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dnase1 deoxyribonuclease 1 decreases expression ISO Menthol results in decreased expression of DNASE1 mRNA CTD PMID:26760959 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 increases expression ISO Menthol results in increased expression of DNASE1L3 mRNA CTD PMID:26760959 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal decreases expression ISO Menthol results in decreased expression of DNASE2 mRNA CTD PMID:26760959 NCBI chr19:23,244,661...23,247,329
Ensembl chr19:23,244,664...23,247,376
JBrowse link
G Dock1 dedicator of cyto-kinesis 1 decreases expression ISO Menthol results in decreased expression of DOCK1 mRNA CTD PMID:26760959 NCBI chr 1:189,467,143...189,983,777
Ensembl chr 1:189,467,143...189,983,768
JBrowse link
G Dpf2 double PHD fingers 2 decreases expression ISO Menthol results in decreased expression of DPF2 mRNA CTD PMID:26760959 NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Menthol results in increased expression of E2F1 mRNA CTD PMID:26760959 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f3 E2F transcription factor 3 decreases expression ISO Menthol results in decreased expression of E2F3 mRNA CTD PMID:26760959 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Menthol results in decreased expression of E2F5 mRNA CTD PMID:26760959 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO Menthol results in decreased expression of EEF1A1 mRNA CTD PMID:26760959 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma decreases expression ISO Menthol results in decreased expression of EEF1G protein CTD PMID:26760959 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein decreases expression ISO Menthol results in decreased expression of EI24 mRNA CTD PMID:26760959 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 decreases expression ISO Menthol results in decreased expression of EIF4G2 mRNA CTD PMID:26760959 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Menthol results in increased expression of EMP3 mRNA CTD PMID:26760959 NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO Menthol results in decreased expression of EP300 mRNA CTD PMID:26760959 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit increases expression ISO Menthol results in increased expression of ERCC2 mRNA CTD PMID:26760959 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit increases expression ISO Menthol results in increased expression of ERCC3 mRNA CTD PMID:26760959 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO Menthol results in decreased expression of FADD mRNA CTD PMID:26760959 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Faf1 Fas associated factor 1 decreases expression ISO Menthol results in decreased expression of FAF1 mRNA CTD PMID:26760959 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Menthol results in decreased expression of FAS mRNA CTD PMID:26760959 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO Menthol results in increased expression of FASLG mRNA CTD PMID:26760959 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO Menthol results in decreased expression of FASTK mRNA CTD PMID:26760959 NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430
JBrowse link
G Fcmr Fc fragment of IgM receptor increases expression ISO Menthol results in increased expression of FCMR mRNA CTD PMID:26760959 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Menthol results in increased expression of FOS protein CTD PMID:18343574 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxk2 forkhead box K2 increases expression ISO Menthol results in increased expression of FOXK2 mRNA CTD PMID:26760959 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563
JBrowse link
G Gab1 GRB2-associated binding protein 1 increases expression ISO Menthol results in increased expression of GAB1 mRNA CTD PMID:26760959 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Menthol results in decreased expression of GADD45A mRNA CTD PMID:26760959 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Menthol results in increased expression of GAPDH mRNA CTD PMID:26760959 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Glo1 glyoxalase 1 increases expression ISO Menthol results in increased expression of GLO1 protein CTD PMID:26760959 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO Menthol results in decreased expression of GRB2 mRNA CTD PMID:26760959 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 increases expression ISO Menthol results in increased expression of GRID2 mRNA CTD PMID:26760959 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C decreases expression ISO Menthol results in decreased expression of GRIN2C mRNA CTD PMID:26760959 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Gsn gelsolin decreases expression ISO Menthol results in decreased expression of GSN mRNA CTD PMID:26760959 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO Menthol results in increased expression of GSTO1 mRNA CTD PMID:26760959 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gzmb granzyme B increases expression ISO Menthol results in increased expression of GZMB mRNA CTD PMID:26760959 NCBI chr15:30,343,361...30,346,792 JBrowse link
G Hcst hematopoietic cell signal transducer decreases expression ISO Menthol results in decreased expression of HCST mRNA CTD PMID:26760959 NCBI chr 1:85,676,976...85,679,083
Ensembl chr 1:85,676,979...85,679,012
JBrowse link
G Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 increases expression ISO Menthol results in increased expression of HNRNPUL1 mRNA CTD PMID:26760959 NCBI chr 1:81,228,404...81,264,121
Ensembl chr 1:81,228,404...81,262,592
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Menthol results in decreased expression of HSP90AB1 mRNA; Menthol results in decreased expression of HSP90AB1 protein CTD PMID:26760959 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Menthol results in decreased expression of HSP90B1 mRNA; Menthol results in decreased expression of HSP90B1 protein CTD PMID:26760959 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Menthol results in increased expression of HSPA5 mRNA; Menthol results in increased expression of HSPA5 protein CTD PMID:26760959 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Menthol results in decreased expression of HSPD1 mRNA CTD PMID:26760959 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression ISO Menthol results in decreased expression of HSPE1 mRNA CTD PMID:26760959 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Menthol results in increased expression of HTATIP2 mRNA CTD PMID:26760959 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Htt huntingtin decreases expression ISO Menthol results in decreased expression of HTT mRNA CTD PMID:26760959 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Menthol results in decreased expression of IGF1 mRNA CTD PMID:26760959 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO Menthol results in decreased expression of IGF1R mRNA CTD PMID:26760959 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression ISO Menthol results in increased expression of IGF2R mRNA CTD PMID:26760959 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit increases expression ISO Menthol results in increased expression of IGFALS mRNA CTD PMID:26760959 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Menthol results in increased expression of IGFBP2 mRNA CTD PMID:26760959 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Menthol results in decreased expression of IGFBP4 mRNA CTD PMID:26760959 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Menthol results in decreased expression of IGFBP5 mRNA CTD PMID:26760959 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO Menthol results in increased expression of IGFBP6 mRNA CTD PMID:26760959 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma decreases expression ISO Menthol results in decreased expression of IKBKG mRNA CTD PMID:26760959 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il16 interleukin 16 decreases expression ISO Menthol results in decreased expression of IL16 mRNA CTD PMID:26760959 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Menthol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]
Menthol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]
CTD PMID:20304105 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO Menthol results in increased expression of IL2 mRNA CTD PMID:26760959 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il24 interleukin 24 decreases expression ISO Menthol results in decreased expression of IL24 mRNA CTD PMID:26760959 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il3 interleukin 3 decreases expression ISO Menthol results in decreased expression of IL3 mRNA CTD PMID:26760959 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il6 interleukin 6 increases secretion ISO Menthol results in increased secretion of IL6 protein CTD PMID:32950532 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ing1 inhibitor of growth family, member 1 increases expression ISO Menthol results in increased expression of ING1 mRNA CTD PMID:26760959 NCBI chr16:77,937,276...77,945,320
Ensembl chr16:77,937,279...77,946,264
JBrowse link
G Irf1 interferon regulatory factor 1 decreases expression ISO Menthol results in decreased expression of IRF1 mRNA CTD PMID:26760959 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Menthol results in increased expression of JUN mRNA CTD PMID:26760959 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Menthol results in decreased expression of JUNB mRNA CTD PMID:26760959 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Menthol results in increased expression of JUND mRNA CTD PMID:26760959 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kdm5a lysine demethylase 5A decreases expression ISO Menthol results in decreased expression of KDM5A mRNA CTD PMID:26760959 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422
JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Menthol results in increased expression of KDR mRNA CTD PMID:26760959 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Menthol results in increased expression of KIF20A mRNA CTD PMID:26760959 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kitlg KIT ligand multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of KITLG protein CTD PMID:27818348 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of LAMTOR3 protein CTD PMID:27818348 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Menthol results in increased expression of LITAF mRNA CTD PMID:26760959 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lmna lamin A/C increases expression ISO Menthol results in increased expression of LMNA mRNA CTD PMID:26760959 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lmnb1 lamin B1 increases expression ISO Menthol results in increased expression of LMNB1 mRNA CTD PMID:26760959 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Ltbr lymphotoxin beta receptor increases expression ISO Menthol results in increased expression of LTBR mRNA CTD PMID:26760959 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Madd MAP-kinase activating death domain increases expression ISO Menthol results in increased expression of MADD mRNA CTD PMID:26760959 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression ISO Menthol results in decreased expression of MAP2K1 mRNA CTD PMID:26760959 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases expression ISO Menthol results in increased expression of MAP2K4 mRNA CTD PMID:26760959 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO Menthol results in decreased expression of MAP2K6 mRNA CTD PMID:26760959 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 decreases expression ISO Menthol results in decreased expression of MAP2K7 mRNA CTD PMID:26760959 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO Menthol results in increased expression of MAP3K1 mRNA CTD PMID:26760959 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 increases expression ISO Menthol results in increased expression of MAP3K14 mRNA CTD PMID:26760959 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 decreases expression ISO Menthol results in decreased expression of MAP3K3 mRNA CTD PMID:26760959 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Mapk10 mitogen activated protein kinase 10 decreases expression ISO Menthol results in decreased expression of MAPK10 mRNA CTD PMID:26760959 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Menthol results in increased phosphorylation of MAPK8 protein CTD PMID:18955132 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Menthol results in increased expression of MCL1 mRNA CTD PMID:26760959 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdm4 MDM4 regulator of p53 increases expression ISO Menthol results in increased expression of MDM4 mRNA CTD PMID:26760959 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression ISO Menthol results in increased expression of MFGE8 mRNA CTD PMID:26760959 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Moap1 modulator of apoptosis 1 decreases expression ISO Menthol results in decreased expression of MOAP1 mRNA CTD PMID:26760959 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of MPC2 protein CTD PMID:27818348 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664
JBrowse link
G Mpg N-methylpurine-DNA glycosylase decreases expression ISO Menthol results in decreased expression of MPG mRNA CTD PMID:26760959 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Menthol results in decreased expression of COX2 protein CTD PMID:32783911 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO Menthol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; Menthol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] CTD PMID:20304105 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO Menthol results in decreased expression of MYB mRNA CTD PMID:26760959 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Menthol results in decreased expression of MYCN mRNA CTD PMID:26760959 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 increases expression ISO Menthol results in increased expression of NAIP mRNA CTD PMID:26760959 NCBI chr 2:31,507,423...31,559,098 JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 increases expression ISO Menthol results in increased expression of NDUFA12 mRNA CTD PMID:26760959 NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression ISO Menthol results in decreased expression of NDUFB8 protein CTD PMID:32783911 NCBI chr 1:243,408,659...243,413,701
Ensembl chr 1:243,408,619...243,413,817
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 increases expression ISO Menthol results in increased expression of NFATC1 mRNA CTD PMID:26760959 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases expression ISO Menthol results in increased expression of NFATC2 mRNA CTD PMID:26760959 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO Menthol results in decreased expression of NFKB1 mRNA CTD PMID:26760959 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO Menthol results in increased expression of NGFR mRNA CTD PMID:26760959 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 decreases expression ISO Menthol results in decreased expression of NLRC4 mRNA CTD PMID:26760959 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A increases expression ISO Menthol results in increased expression of NLRP1 mRNA CTD PMID:26760959 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B increases expression ISO Menthol results in increased expression of CARD8 mRNA CTD PMID:26760959 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 decreases expression ISO Menthol results in decreased expression of NME3 mRNA CTD PMID:26760959 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359
JBrowse link
G Nme5 NME/NM23 family member 5 decreases expression ISO Menthol results in decreased expression of NME5 mRNA CTD PMID:26760959 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794
JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 decreases expression ISO Menthol results in decreased expression of NME6 mRNA CTD PMID:26760959 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 decreases expression ISO Menthol results in decreased expression of NOD1 mRNA CTD PMID:26760959 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 increases expression ISO Menthol results in increased expression of NOD2 mRNA CTD PMID:26760959 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nol3 nucleolar protein 3 increases expression ISO Menthol results in increased expression of NOL3 mRNA CTD PMID:26760959 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO Menthol results in increased expression of NOS1 mRNA CTD PMID:26760959 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects localization ISO Menthol affects the localization of NR1I2 protein CTD PMID:24594507 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization ISO Menthol affects the localization of NR1I3 protein CTD PMID:24594507 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrp1 neuropilin 1 increases expression ISO Menthol results in increased expression of NRP1 mRNA CTD PMID:26760959 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nrp2 neuropilin 2 decreases expression ISO Menthol results in decreased expression of NRP2 mRNA CTD PMID:26760959 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor increases expression ISO Menthol results in increased expression of NSMAF mRNA CTD PMID:26760959 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 increases expression ISO Menthol results in increased expression of NUMA1 mRNA CTD PMID:26760959 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
JBrowse link
G Nup62 nucleoporin 62 decreases expression ISO Menthol results in decreased expression of NUP62 mRNA CTD PMID:26760959 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression ISO Menthol results in increased expression of PAK2 mRNA CTD PMID:26760959 NCBI chr11:68,708,070...68,766,622
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Park7 Parkinsonism associated deglycase decreases expression ISO Menthol results in decreased expression of PARK7 protein CTD PMID:26760959 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp8 poly (ADP-ribose) polymerase family, member 8 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of PARP8 protein CTD PMID:27818348 NCBI chr 2:48,679,405...48,848,700
Ensembl chr 2:48,679,436...48,849,253
JBrowse link
G Pawr pro-apoptotic WT1 regulator increases expression ISO Menthol results in increased expression of PAWR mRNA CTD PMID:26760959 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pdcd2 programmed cell death 2 decreases expression ISO Menthol results in decreased expression of PDCD2 mRNA CTD PMID:26760959 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
JBrowse link
G Pdcd5 programmed cell death 5 decreases expression ISO Menthol results in decreased expression of PDCD5 mRNA CTD PMID:26760959 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
JBrowse link
G Pdcd6 programmed cell death 6 decreases expression ISO Menthol results in decreased expression of PDCD6 mRNA CTD PMID:26760959 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
JBrowse link
G Pde1b phosphodiesterase 1B decreases expression ISO Menthol results in decreased expression of PDE1B mRNA CTD PMID:26760959 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 increases expression ISO Menthol results in increased expression of PDIA6 protein CTD PMID:26760959 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pef1 penta-EF hand domain containing 1 increases expression ISO Menthol results in increased expression of PEF1 mRNA CTD PMID:26760959 NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067
JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 increases expression ISO Menthol results in increased expression of PLEKHG5 mRNA CTD PMID:26760959 NCBI chr 5:162,577,999...162,621,518
Ensembl chr 5:162,578,071...162,621,513
JBrowse link
G Plscr1 phospholipid scramblase 1 decreases expression ISO Menthol results in decreased expression of PLSCR1 mRNA CTD PMID:26760959 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Menthol results in decreased expression of PML mRNA CTD PMID:26760959 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Menthol results in increased expression of PPP1R15A mRNA CTD PMID:26760959 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Pqbp1 polyglutamine binding protein 1 increases expression ISO Menthol results in increased expression of PQBP1 mRNA CTD PMID:26760959 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO Menthol results in increased expression of PRDX1 protein CTD PMID:26760959 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression ISO Menthol results in decreased expression of PRDX5 mRNA CTD PMID:26760959 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prf1 perforin 1 decreases expression ISO Menthol results in decreased expression of PRF1 mRNA CTD PMID:26760959 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prodh1 proline dehydrogenase 1 increases expression ISO Menthol results in increased expression of PRODH mRNA CTD PMID:26760959 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
JBrowse link
G Psen1 presenilin 1 decreases expression ISO Menthol results in decreased expression of PSEN1 mRNA CTD PMID:26760959 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 increases expression ISO Menthol results in increased expression of PSMA3 protein CTD PMID:26760959 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression ISO Menthol results in increased expression of PSMA5 protein CTD PMID:26760959 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO Menthol results in decreased expression of PTGES mRNA CTD PMID:26760959 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO Menthol results in decreased expression of PTK2 mRNA CTD PMID:26760959 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 increases expression ISO Menthol results in increased expression of PTPN13 mRNA CTD PMID:26760959 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
JBrowse link
G Pycard PYD and CARD domain containing decreases expression ISO Menthol results in decreased expression of PYCARD mRNA CTD PMID:26760959 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO Menthol results in decreased expression of RAD23B mRNA CTD PMID:26760959 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression ISO Menthol results in decreased expression of RAF1 mRNA CTD PMID:26760959 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions
increases expression
ISO Mevalonic Acid affects the reaction [Menthol analog results in increased expression of RAP1A protein]; Mevalonic Acid affects the reaction [Menthol results in increased expression of RAP1A protein] CTD PMID:12671036 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression ISO Menthol results in increased expression of RB1 mRNA CTD PMID:26760959 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbbp5 RB binding protein 5, histone lysine methyltransferase complex subunit decreases expression ISO Menthol results in decreased expression of RBBP5 mRNA CTD PMID:26760959 NCBI chr13:43,912,254...43,939,107
Ensembl chr13:43,912,254...43,939,107
JBrowse link
G Rbbp6 RB binding protein 6, ubiquitin ligase increases expression ISO Menthol results in increased expression of RBBP6 mRNA CTD PMID:26760959 NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 decreases expression ISO Menthol results in decreased expression of RBL2 mRNA CTD PMID:26760959 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation ISO Menthol results in increased phosphorylation of RELA protein CTD PMID:32950532 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A increases expression
multiple interactions
ISO Menthol analog results in increased expression of RHOA protein
Mevalonic Acid affects the reaction [Menthol analog results in increased expression of RHOA protein]
CTD PMID:12671036 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B increases expression
multiple interactions
ISO Menthol analog results in increased expression of RHOB protein; Menthol results in increased expression of RHOB protein
Mevalonic Acid affects the reaction [Menthol analog results in increased expression of RHOB protein]; Mevalonic Acid affects the reaction [Menthol results in increased expression of RHOB protein]
CTD PMID:12671036 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression ISO Menthol results in increased expression of RIPK1 mRNA CTD PMID:26760959 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression ISO Menthol results in increased expression of RIPK2 mRNA CTD PMID:26760959 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 increases expression ISO Menthol results in increased expression of RIPK3 mRNA CTD PMID:26760959 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Rpl31 ribosomal protein L31 decreases expression ISO Menthol results in decreased expression of RPL31 mRNA CTD PMID:26760959 NCBI chr 9:41,647,401...41,650,886
Ensembl chr 9:41,647,426...41,662,129
JBrowse link
G Rpl7 ribosomal protein L7 increases expression ISO Menthol results in increased expression of RPL7 mRNA CTD PMID:26760959 NCBI chr 5:3,217,184...3,220,192 JBrowse link
G Rps20 ribosomal protein S20 increases expression ISO Menthol results in increased expression of RPS20 mRNA CTD PMID:26760959 NCBI chr 5:16,819,313...16,820,475
Ensembl chr 5:16,819,304...16,820,475
JBrowse link
G Rps3a ribosomal protein S3a increases expression ISO Menthol results in increased expression of RPS3A mRNA CTD PMID:26760959 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps9 ribosomal protein S9 decreases expression ISO Menthol results in decreased expression of RPS9 mRNA CTD PMID:26760959
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression ISO Menthol results in decreased expression of SDHB protein CTD PMID:32783911 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO Menthol results in increased expression of SERPINB9 mRNA CTD PMID:26760959 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Menthol results in increased expression of SFRP1 mRNA CTD PMID:26760959 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 decreases expression ISO Menthol results in decreased expression of SIAH1 mRNA CTD PMID:26760959 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression ISO Menthol results in decreased expression of SLC25A4 mRNA CTD PMID:26760959 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO Menthol results in increased expression of SOD1 mRNA CTD PMID:26760959 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions
increases expression
ISO Menthol results in decreased expression of SOD2 mRNA
TRPM8 protein affects the reaction [Menthol results in increased expression of SOD2 protein]
CTD PMID:26760959 PMID:32950532 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression ISO Menthol results in decreased expression of SPTAN1 mRNA CTD PMID:26760959 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 increases expression ISO Menthol results in increased expression of SPTBN1 mRNA CTD PMID:26760959 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Menthol results in decreased expression of SREBF1 mRNA CTD PMID:26760959 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 decreases expression ISO Menthol results in decreased expression of SREBF2 mRNA CTD PMID:26760959 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Srp72 signal recognition particle 72 decreases expression ISO Menthol results in decreased expression of SRP72 mRNA CTD PMID:26760959 NCBI chr14:31,168,175...31,195,717 JBrowse link
G Stk17b serine/threonine kinase 17b decreases expression ISO Menthol results in decreased expression of STK17B mRNA CTD PMID:26760959 NCBI chr 9:55,307,485...55,338,085
Ensembl chr 9:55,307,668...55,338,031
JBrowse link
G Stx11 syntaxin 11 decreases expression ISO Menthol results in decreased expression of STX11 mRNA CTD PMID:26760959 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Tank TRAF family member-associated NFKB activator decreases expression ISO Menthol results in decreased expression of TANK mRNA CTD PMID:26760959 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264
JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 increases expression ISO Menthol results in increased expression of TDP2 mRNA CTD PMID:26760959 NCBI chr17:40,228,943...40,240,337
Ensembl chr17:40,228,947...40,240,313
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO Menthol results in decreased expression of TFDP1 mRNA CTD PMID:26760959 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tfdp2 transcription factor Dp-2 decreases expression ISO Menthol results in decreased expression of TFDP2 mRNA CTD PMID:26760959 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
JBrowse link
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 decreases expression ISO Menthol results in decreased expression of TIAL1 mRNA CTD PMID:26760959 NCBI chr 1:183,008,358...183,045,092
Ensembl chr 1:183,009,253...183,031,637
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of TIMP1 protein CTD PMID:27818348 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Menthol results in decreased expression of TNF mRNA CTD PMID:26760959 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip1 TNF alpha induced protein 1 decreases expression ISO Menthol results in decreased expression of TNFAIP1 mRNA CTD PMID:26760959 NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Menthol results in increased expression of TNFAIP2 mRNA CTD PMID:26760959 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression ISO Menthol results in decreased expression of TNFAIP3 mRNA CTD PMID:26760959 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Menthol results in decreased expression of TNFAIP6 mRNA CTD PMID:26760959 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 decreases expression ISO Menthol results in decreased expression of TNFAIP8 mRNA CTD PMID:26760959 NCBI chr18:43,183,854...43,299,517
Ensembl chr18:43,183,916...43,299,517
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Menthol results in increased expression of TNFRSF10A mRNA CTD PMID:26760959 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A decreases expression ISO Menthol results in decreased expression of TNFRSF11A mRNA CTD PMID:26760959 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression ISO Menthol results in decreased expression of TNFRSF11B mRNA CTD PMID:26760959 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO Menthol results in increased expression of TNFRSF14 mRNA CTD PMID:26760959 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
G Tnfrsf17 TNF receptor superfamily member 17 increases expression ISO Menthol results in increased expression of TNFRSF17 mRNA CTD PMID:26760959 NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression ISO Menthol results in increased expression of TNFRSF1B mRNA CTD PMID:26760959 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 decreases expression ISO Menthol results in decreased expression of TNFRSF21 mRNA CTD PMID:26760959 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 decreases expression ISO Menthol results in decreased expression of TNFRSF25 mRNA CTD PMID:26760959 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 decreases expression ISO Menthol results in decreased expression of TNFRSF10D mRNA CTD PMID:26760959 NCBI chr 1:198,802,513...198,824,049
Ensembl chr 1:198,802,971...198,823,418
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 decreases expression ISO Menthol results in decreased expression of TNFRSF4 mRNA CTD PMID:26760959 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 decreases expression ISO Menthol results in decreased expression of TNFRSF8 mRNA CTD PMID:26760959 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Menthol results in increased expression of TNFRSF9 mRNA CTD PMID:26760959 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Menthol results in decreased expression of TNFSF10 mRNA CTD PMID:26760959 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf12 TNF superfamily member 12 decreases expression ISO Menthol results in decreased expression of TNFSF12 mRNA CTD PMID:26760959 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213
JBrowse link
G Tnfsf13 TNF superfamily member 13 decreases expression ISO Menthol results in decreased expression of TNFSF13 mRNA CTD PMID:26760959 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
G Tnfsf14 TNF superfamily member 14 decreases expression ISO Menthol results in decreased expression of TNFSF14 mRNA CTD PMID:26760959 NCBI chr 9:2,069,075...2,073,128
Ensembl chr 9:2,069,104...2,073,216
JBrowse link
G Tnfsf15 TNF superfamily member 15 decreases expression ISO Menthol results in decreased expression of TNFSF15 mRNA CTD PMID:26760959 NCBI chr 5:77,140,099...77,156,142
Ensembl chr 5:77,139,878...77,156,228
JBrowse link
G Tnfsf18 TNF superfamily member 18 increases expression ISO Menthol results in increased expression of TNFSF18 mRNA CTD PMID:26760959 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression ISO Menthol results in increased expression of TNFSF4 mRNA CTD PMID:26760959 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tnfsf8 TNF superfamily member 8 decreases expression ISO Menthol results in decreased expression of TNFSF8 mRNA CTD PMID:26760959 NCBI chr 5:77,253,881...77,277,078
Ensembl chr 5:77,251,373...77,277,421
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Menthol results in increased expression of TNFSF9 mRNA CTD PMID:26760959 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
G Top1 DNA topoisomerase I decreases activity
decreases expression
ISO Menthol results in decreased activity of TOP1 protein
Menthol results in decreased expression of TOP1 mRNA
CTD PMID:16158947 PMID:26760959 NCBI chr 3:149,293,658...149,375,405
Ensembl chr 3:149,293,403...149,376,623
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity
increases expression
ISO Menthol results in decreased activity of TOP2A protein
Menthol results in increased expression of TOP2A mRNA
CTD PMID:16158947 PMID:26760959 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Top2b DNA topoisomerase II beta decreases activity
increases expression
ISO Menthol results in decreased activity of TOP2B protein
Menthol results in increased expression of TOP2B mRNA
CTD PMID:16158947 PMID:26760959 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Menthol results in increased expression of TP53 mRNA CTD PMID:26760959 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 increases expression ISO Menthol results in increased expression of TP53BP2 mRNA CTD PMID:26760959 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Menthol results in increased expression of TP53I3 mRNA CTD PMID:26760959 NCBI chr13:69,612,605...69,655,018
Ensembl chr13:69,620,792...69,652,475
JBrowse link
G Tp73 tumor protein p73 decreases expression ISO Menthol results in decreased expression of TP73 mRNA CTD PMID:26760959 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Menthol results in increased expression of TPI1 protein CTD PMID:26760959 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO Menthol results in increased expression of TRADD mRNA CTD PMID:26760959 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Traf1 TNF receptor-associated factor 1 decreases expression ISO Menthol results in decreased expression of TRAF1 mRNA CTD PMID:26760959 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases expression ISO Menthol results in decreased expression of TRAF2 mRNA CTD PMID:26760959 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf3 Tnf receptor-associated factor 3 increases expression ISO Menthol results in increased expression of TRAF3 mRNA CTD PMID:26760959 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 decreases expression ISO Menthol results in decreased expression of TRAF3IP1 mRNA CTD PMID:26760959 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977
JBrowse link
G Traf4 Tnf receptor associated factor 4 decreases expression ISO Menthol results in decreased expression of TRAF4 mRNA CTD PMID:26760959 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
JBrowse link
G Traf5 TNF receptor-associated factor 5 decreases expression ISO Menthol results in decreased expression of TRAF5 mRNA CTD PMID:26760959 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709
JBrowse link
G Traf6 TNF receptor associated factor 6 decreases expression ISO Menthol results in decreased expression of TRAF6 mRNA CTD PMID:26760959 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Traip TRAF-interacting protein decreases expression ISO Menthol results in decreased expression of TRAIP mRNA CTD PMID:26760959 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO Menthol results in increased activity of TRPA1 protein CTD PMID:29054683 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 multiple interactions
decreases response to substance
increases response to substance
affects response to substance
increases activity
ISO
EXP
[Menthol analog binds to and results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; Menthol analog binds to and results in increased activity of TRPM8 protein; Menthol inhibits the reaction [Praziquantel results in increased activity of TRPM8 protein]; Menthol promotes the reaction [TRPM8 protein results in increased transport of Calcium]; Praziquantel inhibits the reaction [Menthol results in increased activity of TRPM8 protein]; TRPM8 protein affects the reaction [Menthol results in increased expression of SOD2 protein]
TRPM8 gene mutant form results in decreased susceptibility to Menthol
TRPM8 protein results in increased susceptibility to Menthol
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [icilin inhibits the reaction [Menthol results in increased activity of TRPM8 protein]]; 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Menthol inhibits the reaction [Menthol results in increased activity of TRPM8 protein]]; 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Menthol inhibits the reaction [Phenylephrine results in increased activity of TRPM8 protein]]; Menthol binds to and results in increased activity of TRPM8 protein; Menthol inhibits the reaction [Phenylephrine results in increased activity of TRPM8 protein]; Menthol inhibits the reaction [Potassium Chloride results in increased activity of TRPM8 protein]
TRPM8 protein affects the susceptibility to Menthol
Menthol results in increased activity of TRPM8; Menthol results in increased activity of TRPM8 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Menthol results in increased activity of TRPM8]; [Menthol binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium
Menthol analog results in increased activity of TRPM8 protein; Menthol results in increased activity of TRPM8 protein
CTD PMID:15046718 PMID:16174775 PMID:16520735 PMID:17481392 PMID:17517434 More... NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity ISO Menthol results in increased activity of TRPV1 protein CTD PMID:29054683 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Tspo translocator protein decreases expression ISO Menthol results in decreased expression of TSPO mRNA CTD PMID:26760959 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of Menthol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of Menthol CTD PMID:11186130 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression ISO Menthol results in decreased expression of VDAC1 mRNA CTD PMID:26760959 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression ISO Menthol results in increased expression of VDAC2 mRNA CTD PMID:26760959 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Menthol results in decreased expression of VEGF mRNA CTD PMID:26760959 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfb vascular endothelial growth factor B increases expression ISO Menthol results in increased expression of VEGFB mRNA CTD PMID:26760959 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression ISO Menthol results in decreased expression of VEGFC mRNA CTD PMID:26760959 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO Menthol results in increased expression of VEGFD mRNA CTD PMID:26760959 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
G Vwf von Willebrand factor multiple interactions EXP [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of VWF protein CTD PMID:27818348 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO Menthol results in increased expression of XIAP mRNA CTD PMID:26760959 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon affects expression ISO Menthol affects the expression of YWHAE protein CTD PMID:26760959 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta decreases expression ISO Menthol results in decreased expression of YWHAZ protein CTD PMID:26760959 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 increases expression ISO Menthol results in increased expression of ZFP36L1 mRNA CTD PMID:26760959 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp709 zinc finger protein 709 decreases expression ISO Menthol results in decreased expression of ZNF443 mRNA CTD PMID:26760959 NCBI chr16:17,907,599...17,920,047
Ensembl chr16:17,909,641...17,919,700
JBrowse link
G Zranb1 zinc finger RANBP2-type containing 1 decreases expression ISO Menthol results in decreased expression of ZRANB1 mRNA CTD PMID:26760959 NCBI chr 1:187,725,354...187,780,129
Ensembl chr 1:187,724,320...187,779,655
JBrowse link
perillyl alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 increases expression ISO perillyl alcohol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of BAX protein] CTD PMID:19161993 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein] CTD PMID:19161993 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cat catalase multiple interactions ISO
EXP
perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
perillyl alcohol inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD PMID:19161993 PMID:20923693 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO perillyl alcohol results in decreased expression of CCNA2 protein CTD PMID:17138864 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO perillyl alcohol results in decreased expression of CCNB1 protein CTD PMID:17138864 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
ISO perillyl alcohol results in decreased expression of CDK2 protein
perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; perillyl alcohol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases response to substance
multiple interactions
increases expression
ISO CDKN1A protein results in increased susceptibility to perillyl alcohol
perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
perillyl alcohol results in increased expression of CDKN1A protein
CTD PMID:17138864 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases response to substance
increases expression
multiple interactions
ISO CDKN1B protein results in increased susceptibility to perillyl alcohol
perillyl alcohol results in increased expression of CDKN1B protein
perillyl alcohol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO perillyl alcohol results in increased expression of FBXO32 mRNA; perillyl alcohol results in increased expression of FBXO32 protein CTD PMID:19406843 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha multiple interactions EXP [Vitamin A co-treated with perillyl alcohol] results in decreased expression of FNTA protein CTD PMID:15959631 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta multiple interactions
increases expression
decreases expression
EXP [perillyl alcohol co-treated with Vitamin A] results in decreased expression of FNTB mRNA
perillyl alcohol results in increased expression of FNTB protein
perillyl alcohol results in decreased expression of FNTB mRNA
CTD PMID:15959631 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]
perillyl alcohol inhibits the reaction [Ethanol results in decreased activity of GSR protein]
CTD PMID:19161993 PMID:20923693 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions EXP perillyl alcohol inhibits the reaction [Ethanol results in decreased activity of H6PD protein] CTD PMID:20923693 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Ivl involucrin decreases expression ISO perillyl alcohol results in decreased expression of IVL protein CTD PMID:10769631 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] CTD PMID:19161993 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:19161993 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] CTD PMID:19161993 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein] CTD PMID:19161993 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions
increases expression
ISO Mevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RAP1A protein] CTD PMID:12671036 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP perillyl alcohol inhibits the reaction [Ethanol results in increased activity of RELA protein] CTD PMID:20923693 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression
ISO
EXP
Mevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RHOA protein]
[perillyl alcohol co-treated with Vitamin A] results in increased expression of RHOA mRNA
CTD PMID:12671036 PMID:15959631 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B multiple interactions
increases expression
ISO
EXP
Mevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RHOB protein]
perillyl alcohol results in increased expression of RHOB mRNA; perillyl alcohol results in increased expression of RHOB protein
[perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB mRNA; [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB protein
CTD PMID:12671036 PMID:15959631 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP perillyl alcohol inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:20923693 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
tea tree oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO Tea Tree Oil results in increased activity of ESR1 protein CTD PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO Tea Tree Oil results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]
CTD PMID:31393563 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
terpinolene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO terpinolene results in decreased expression of AKT1 protein CTD PMID:22740904 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    chemical entity 19823
      atom 19821
        nonmetal atom 19709
          carbon atom 19633
            organic molecular entity 19633
              organic fundamental parent 18361
                natural product fundamental parent 13396
                  terpenoid fundamental parent 3517
                    p-menthane 485
                      (+)-trans-2-menthene 0
                      (1R,4R)-4-isopropenyl-1-methyl-2-methylenecyclohexane 0
                      (4R,7R)-7-isopropenyl-4-methyl-1-oxaspiro[2.5]octane 0
                      1-methyl-4-(propan-2-yl)cyclohex-1-ene + 0
                      1-p-menth-1-ene-9-al 0
                      4-isopropyl-1-methylcyclohexane 1-hydroperoxide 0
                      4-isopropyl-1-methylenecyclohexane 0
                      limonene + 93
                      p-mentha-1,3,8-triene 0
                      p-menthadiene + 10
                      p-menthane monoterpenoid + 437
                      p-menthane-3,8-diol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    main group molecular entity 19720
                      s-block molecular entity 19502
                        hydrogen molecular entity 19495
                          hydrides 18855
                            organic hydride 18361
                              organic fundamental parent 18361
                                hydrocarbon 18074
                                  terpene 12719
                                    monoterpene 2859
                                      p-menthane 485
                                        (+)-trans-2-menthene 0
                                        (1R,4R)-4-isopropenyl-1-methyl-2-methylenecyclohexane 0
                                        (4R,7R)-7-isopropenyl-4-methyl-1-oxaspiro[2.5]octane 0
                                        1-methyl-4-(propan-2-yl)cyclohex-1-ene + 0
                                        1-p-menth-1-ene-9-al 0
                                        4-isopropyl-1-methylcyclohexane 1-hydroperoxide 0
                                        4-isopropyl-1-methylenecyclohexane 0
                                        limonene + 93
                                        p-mentha-1,3,8-triene 0
                                        p-menthadiene + 10
                                        p-menthane monoterpenoid + 437
                                        p-menthane-3,8-diol + 0
paths to the root