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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxide
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Accession:CHEBI:25741 term browser browse the term
Definition:An oxide is a chemical compound of oxygen with other chemical elements.
Synonyms:related_synonym: oxides


show annotations for term's descendants           Sort by:
(R)-carnitine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A5 solute carrier family 22 member 5 increases uptake EXP SLC22A5 protein results in increased uptake of Carnitine CTD PMID:16826461 NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219 		JBrowse link
aluminium oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Aluminum Oxide results in increased expression of ICAM1 protein CTD PMID:18456438 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G SELE selectin E increases expression EXP Aluminum Oxide results in increased expression of SELE mRNA; Aluminum Oxide results in increased expression of SELE protein CTD PMID:18456438 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression EXP Aluminum Oxide results in increased expression of VCAM1 mRNA; Aluminum Oxide results in increased expression of VCAM1 protein CTD PMID:18456438 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
cadmium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule affects expression EXP cadmium nitrate affects the expression of CD14 mRNA CTD PMID:29421334 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 affects expression
affects secretion		 EXP cadmium nitrate affects the expression of CXCL8 mRNA
cadmium nitrate affects the secretion of CXCL8 protein		 CTD PMID:29421334 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G DEFB1 defensin beta 1 increases expression EXP cadmium nitrate results in increased expression of DEFB1 mRNA CTD PMID:29421334
G IFNB1 interferon beta 1 increases expression EXP cadmium nitrate results in increased expression of IFNB1 mRNA CTD PMID:29421334 NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495 		JBrowse link
G IL18 interleukin 18 increases expression EXP cadmium nitrate results in increased expression of IL18 mRNA CTD PMID:29421334 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL6 interleukin 6 increases expression EXP cadmium nitrate results in increased expression of IL6 mRNA CTD PMID:29421334 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression EXP cadmium nitrate results in increased expression of IL1B mRNA CTD PMID:29421334
G MAPK14 mitogen-activated protein kinase 14 affects expression EXP cadmium nitrate affects the expression of MAPK14 mRNA CTD PMID:29421334 NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,877...31,862,031 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases expression EXP cadmium nitrate results in increased expression of MAPK8 mRNA CTD PMID:29421334 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor affects expression EXP cadmium nitrate affects the expression of MYD88 mRNA CTD PMID:29421334 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 affects expression EXP cadmium nitrate affects the expression of NFKB1 mRNA CTD PMID:29421334 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases expression EXP cadmium nitrate results in increased expression of RELA mRNA CTD PMID:29421334 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 decreases expression EXP cadmium nitrate results in decreased expression of SOCS1 mRNA CTD PMID:29421334 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 decreases expression EXP cadmium nitrate results in decreased expression of STAT3 mRNA CTD PMID:29421334 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G TLR4 toll like receptor 4 affects expression EXP cadmium nitrate affects the expression of TLR4 mRNA CTD PMID:29421334 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR5 toll like receptor 5 increases expression EXP cadmium nitrate results in increased expression of TLR5 mRNA CTD PMID:29421334 NCBI chr10:19,387,666...19,410,024
Ensembl chr10:19,387,666...19,410,024 		JBrowse link
G TNF tumor necrosis factor increases expression EXP cadmium nitrate results in increased expression of TNF mRNA CTD PMID:29421334 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
CAR(3:0(Me2)) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A5 solute carrier family 22 member 5 decreases activity EXP pivaloylcarnitine results in decreased activity of SLC22A5 protein CTD PMID:16826461 NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219 		JBrowse link
carbon dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 multiple interactions EXP [Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein; Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein] CTD PMID:28506824 NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294 		JBrowse link
G ADCYAP1R1 ADCYAP receptor type I multiple interactions EXP [Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1R1 protein CTD PMID:28506824 NCBI chr18:41,915,180...41,972,327
Ensembl chr18:41,917,428...41,972,301 		JBrowse link
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA2 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA2 protein] CTD PMID:28235547 NCBI chr14:11,193,732...11,204,334
Ensembl chr14:11,195,228...11,207,650 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein] CTD PMID:28235547 NCBI chr 7:47,361,710...47,382,743
Ensembl chr 7:47,361,899...47,384,303 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA7 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA7 protein] CTD PMID:28235547 NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,698...142,937,788 		JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA9 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA9 protein] CTD PMID:28235547 NCBI chr 8:31,430,933...31,456,385
Ensembl chr 8:31,443,043...31,456,384 		JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNB2 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNB2 protein] CTD PMID:28235547 NCBI chr 4:95,196,992...95,211,084
Ensembl chr 4:95,198,717...95,211,037 		JBrowse link
carbon monoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions EXP CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] CTD PMID:21984542 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP [HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide; chromium mesoporphyrin inhibits the reaction [[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide]; tin protoporphyrin IX inhibits the reaction [[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide] CTD PMID:16751286
G NFKBIA NFKB inhibitor alpha multiple interactions EXP NFKBIA protein inhibits the reaction [Carbon Monoxide results in decreased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP NFKBIA protein inhibits the reaction [Carbon Monoxide results in decreased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions EXP [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide; CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] CTD PMID:21984542 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169 		JBrowse link
flunixin meglumine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 affects expression EXP flunixin meglumine affects the expression of ABCB1 mRNA CTD PMID:26366864 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 affects expression EXP flunixin meglumine affects the expression of CYP1A2 mRNA CTD PMID:26366864 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects expression EXP flunixin meglumine affects the expression of CYP2E1 mRNA CTD PMID:26366864 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
G CYP3A22 cytochrome P450 family 3 subfamily A member 22 affects expression EXP flunixin meglumine affects the expression of CYP3A22 mRNA CTD PMID:26366864 NCBI chr 3:6,617,256...6,665,179
Ensembl chr 3:6,615,343...6,822,817 		JBrowse link
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 affects expression EXP flunixin meglumine affects the expression of CYP3A29 mRNA CTD PMID:26366864 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944 		JBrowse link
G LOC110262013 sulfotransferase 1 family member D1 affects expression EXP flunixin meglumine affects the expression of SULT1A1 mRNA CTD PMID:26366864 NCBI chr 8:66,762,885...66,789,582 JBrowse link
hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 decreases activity
multiple interactions		 EXP Hydrogen Peroxide results in decreased activity of ALDH7A1 protein
Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein]; Mercaptoethanol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein]; NAD promotes the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein]		 CTD PMID:21296058 NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity		 EXP Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein] CTD PMID:15191356 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CAT catalase decreases response to substance
multiple interactions		 EXP CAT results in decreased susceptibility to Hydrogen Peroxide
CAT protein inhibits the reaction [Paraquat results in increased abundance of Hydrogen Peroxide]		 CTD PMID:11039594 PMID:18086661 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Hydrogen Peroxide results in increased expression of CXCL8 mRNA CTD PMID:22083491 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Hydrogen Peroxide results in increased expression of FOS mRNA CTD PMID:18086661 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 EXP Hydrogen Peroxide results in increased expression of HSPA5 protein
Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of HSPA5 protein]; nimesulide inhibits the reaction [Hydrogen Peroxide results in increased expression of HSPA5 protein]		 CTD PMID:20665602 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:11325585 PMID:21798251 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions		 EXP Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein
3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]		 CTD PMID:11325585 PMID:21798251 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation EXP Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:11325585 PMID:18086661 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases phosphorylation EXP Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein CTD PMID:11325585 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions EXP [sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide CTD PMID:12530527 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G TNF tumor necrosis factor increases expression EXP Hydrogen Peroxide results in increased expression of TNF mRNA CTD PMID:22083491 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions EXP [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Hydrogen Peroxide CTD PMID:21984542 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169 		JBrowse link
monosodium L-glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions		 EXP Sodium Glutamate results in increased expression of ACACA mRNA
Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of ACACA mRNA]		 CTD PMID:31360149 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 increases expression EXP Sodium Glutamate results in increased expression of ACOX1 mRNA CTD PMID:31360149 NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546 		JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression		 EXP Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA] CTD PMID:31360149 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G FFAR1 free fatty acid receptor 1 affects expression EXP Sodium Glutamate affects the expression of FFAR1 mRNA CTD PMID:31360149 NCBI chr 6:44,837,764...44,841,518 JBrowse link
G FFAR2 free fatty acid receptor 2 multiple interactions
affects expression		 EXP Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR2 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR2 mRNA] CTD PMID:31360149 NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,901,159...44,904,459 		JBrowse link
G FFAR4 free fatty acid receptor 4 affects expression
multiple interactions		 EXP Sodium Glutamate affects the expression of FFAR4 mRNA
Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR4 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR4 mRNA]		 CTD PMID:31360149 Ensembl chr14:105,011,942...105,037,498 JBrowse link
G GPR119 G protein-coupled receptor 119 affects expression
multiple interactions		 EXP Sodium Glutamate affects the expression of GPR119 mRNA
Dietary Fats affects the reaction [Sodium Glutamate affects the expression of GPR119 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of GPR119 mRNA]		 CTD PMID:31360149 NCBI chr  X:106,872,225...106,873,299
Ensembl chr  X:106,872,225...106,873,299 		JBrowse link
G LOC110255234 liver carboxylesterase-like multiple interactions EXP Sodium Glutamate inhibits the reaction [Dietary Fats results in decreased expression of CES1 mRNA] CTD PMID:31360149
G PNPLA2 patatin like phospholipase domain containing 2 increases expression EXP Sodium Glutamate results in increased expression of PNPLA2 mRNA CTD PMID:31360149 NCBI chr 2:513,065...517,962
Ensembl chr 2:513,077...518,182 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 EXP Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of SREBF1 mRNA] CTD PMID:31360149 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
nitric oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 multiple interactions EXP ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] CTD PMID:12672649 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703 		JBrowse link
G AGT angiotensinogen affects activity EXP Nitric Oxide affects the activity of AGT protein CTD PMID:21127344 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G CAPN1 calpain 1 decreases expression EXP Nitric Oxide results in decreased expression of CAPN1 mRNA CTD PMID:9728040 NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,985...7,022,684 		JBrowse link
G EDN1 endothelin 1 increases abundance
multiple interactions		 EXP EDN1 protein results in increased abundance of Nitric Oxide
Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein]		 CTD PMID:12672649 PMID:17105827 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G KDSR 3-ketodihydrosphingosine reductase multiple interactions EXP Nitric Oxide results in increased phosphorylation of and results in decreased activity of BCL2 protein CTD PMID:16039061 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G KNG1 kininogen 1 multiple interactions
increases abundance		 EXP ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] CTD PMID:12672649 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,340...124,557,958 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP Resveratrol inhibits the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide] CTD PMID:20825639 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
decreases activity		 EXP TXNRD1 protein inhibits the reaction [Nitric Oxide results in decreased activity of NOS3 protein] CTD PMID:8810647 PMID:10823391 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G TAC1 tachykinin precursor 1 increases abundance EXP TAC1 protein results in increased abundance of Nitric Oxide CTD PMID:12672649 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523 		JBrowse link
G TXNRD1 thioredoxin reductase 1 multiple interactions EXP TXNRD1 protein inhibits the reaction [Nitric Oxide results in decreased activity of NOS3 protein] CTD PMID:8810647 NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,172,260...80,236,219 		JBrowse link
nitrogen dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAPN1 calpain 1 decreases expression EXP Nitrogen Dioxide results in decreased expression of CAPN1 mRNA CTD PMID:9728040 NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,985...7,022,684 		JBrowse link
O-acetyl-L-carnitine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A5 solute carrier family 22 member 5 increases uptake EXP SLC22A5 protein results in increased uptake of Acetylcarnitine CTD PMID:16826461 NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219 		JBrowse link
potassium chromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAPDH glyceraldehyde-3-phosphate dehydrogenase decreases activity EXP potassium chromate(VI) results in decreased activity of GAPDH protein CTD PMID:26582256 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
S-adenosyl-L-methioninate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMT catechol-O-methyltransferase multiple interactions EXP [S-Adenosylmethionine analog co-treated with COMT protein] results in increased methylation of catechol CTD PMID:20196537 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998 		JBrowse link
sodium benzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAO D-amino acid oxidase decreases activity EXP Sodium Benzoate results in decreased activity of DAO protein CTD PMID:20952482 NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,931,541...41,950,633 		JBrowse link
sodium dichromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 decreases expression EXP sodium bichromate results in decreased expression of AKT1 protein CTD PMID:12760830
sodium disulfite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP sodium metabisulfite inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA] CTD PMID:33817499 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP sodium metabisulfite inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA] CTD PMID:33817499 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
sodium hydrogencarbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAPDH glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein CTD PMID:26582256 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
sodium perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A5 solute carrier family 5 member 5 multiple interactions EXP sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] CTD PMID:12586784 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
G TPO thyroid peroxidase decreases activity EXP sodium perchlorate results in decreased activity of TPO protein CTD PMID:23959146 NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208 		JBrowse link
thymol sulfate(1-) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RYR1 ryanodine receptor 1 increases activity EXP Thymol results in increased activity of RYR1 protein CTD PMID:17641978 NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5007
    chemical entity 5007
      group 4986
        polyatomic entity 4986
          heteroatomic molecular entity 4957
            oxide 73
              N-oxide + 0
              Se-oxide + 0
              inorganic oxide + 28
              organic oxide + 12
              oxoanion + 41
              peroxides + 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 5007
    subatomic particle 4998
      composite particle 4998
        hadron 4998
          baryon 4998
            nucleon 4998
              atomic nucleus 4998
                atom 4998
                  main group element atom 4964
                    main group molecular entity 4963
                      p-block molecular entity 4961
                        chalcogen molecular entity 4866
                          oxygen molecular entity 4832
                            oxide 73
                              N-oxide + 0
                              Se-oxide + 0
                              inorganic oxide + 28
                              organic oxide + 12
                              oxoanion + 41
                              peroxides + 13
paths to the root