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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organoselenium compound
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Accession:CHEBI:25712 term browser browse the term
Definition:An organoselenium compound is a compound containing at least one carbon-selenium bond.
Synonyms:related_synonym: organoselenium compounds
 alt_id: MESH:D016566
 xref_mesh: MESH:D016566



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organoselenium compound term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA CTD PMID:25167922 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein]
[Organoselenium Compounds binds to Copper] which results in decreased expression of AKT1 protein
CTD PMID:18538761 PMID:25167922 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein] CTD PMID:25301743 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] CTD PMID:25301743 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases cleavage ISO Organoselenium Compounds results in increased cleavage of CASP3 protein CTD PMID:24905917 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein] CTD PMID:25301743 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Organoselenium Compounds binds to and results in decreased activity of CYP1A1 protein CTD PMID:21732699 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Organoselenium Compounds binds to and results in decreased activity of CYP1A2 protein CTD PMID:21732699 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Organoselenium Compounds binds to and results in decreased activity of CYP1B1 protein CTD PMID:21732699 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJA1 mRNA CTD PMID:25167922 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJA4 mRNA CTD PMID:25167922 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB1 mRNA CTD PMID:25167922 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB4 mRNA CTD PMID:25167922 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB6 mRNA CTD PMID:25167922 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB9 mRNA CTD PMID:25167922 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of EGLN3 mRNA CTD PMID:25167922 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO Organoselenium Compounds results in increased activity of EPHX1 protein CTD PMID:17163488 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein] CTD PMID:25301743 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of FOS mRNA CTD PMID:25167922 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of FOSL1 mRNA CTD PMID:25167922 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of GCLM mRNA CTD PMID:25167922 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO [Organoselenium Compounds co-treated with Lipopolysaccharides] results in increased expression of GPX1 protein
Organoselenium Compounds results in increased expression of GPX1 protein
CTD PMID:20883674 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HERPUD1 mRNA CTD PMID:25167922 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HMOX1 mRNA CTD PMID:25167922 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of HSP90AA1 protein; [Organoselenium Compounds binds to Copper] which results in increased expression of HSP90AA1 mRNA CTD PMID:25167922 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1A mRNA CTD PMID:25167922
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1B mRNA CTD PMID:25167922 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1L mRNA CTD PMID:25167922 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPB8 mRNA CTD PMID:25167922 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPH1 mRNA CTD PMID:25167922 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ifng interferon gamma multiple interactions ISO Organoselenium Compounds inhibits the reaction [Freund's Adjuvant results in increased expression of IFNG mRNA] CTD PMID:31400342 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:18538761 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of JUN mRNA CTD PMID:25167922 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of JUNB mRNA CTD PMID:25167922 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA6 mRNA CTD PMID:25167922 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MAFF mRNA CTD PMID:25167922 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MAFG mRNA CTD PMID:25167922 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of MAP2K6 mRNA CTD PMID:25167922 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
increases activity
EXP Organoselenium Compounds analog results in increased phosphorylation of MAPK1 protein
Organoselenium Compounds results in increased activity of MAPK1 protein
CTD PMID:21960664 PMID:22001386 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MAPK15 mRNA CTD PMID:25167922 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
increases phosphorylation
EXP Organoselenium Compounds results in increased activity of MAPK3 protein
Organoselenium Compounds analog results in increased phosphorylation of MAPK3 protein
CTD PMID:21960664 PMID:22001386 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA CTD PMID:25167922 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp10 matrix metallopeptidase 10 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MMP10 mRNA CTD PMID:25167922 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp25 matrix metallopeptidase 25 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MMP25 mRNA CTD PMID:25167922 NCBI chr10:12,661,297...12,676,119 JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MT2A mRNA CTD PMID:25167922 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of NOS2 protein]
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
CTD PMID:18538761 PMID:20883674 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Organoselenium Compounds results in increased cleavage of PARP1 protein CTD PMID:24905917 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pgf placental growth factor multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of PGF mRNA CTD PMID:25167922 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of PIK3R5 mRNA CTD PMID:25167922 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of PIM1 protein; [Organoselenium Compounds binds to Copper] which results in increased expression of PIM1 mRNA CTD PMID:25167922 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of PPP1R15A mRNA CTD PMID:25167922 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
ISO
EXP
Organoselenium Compounds inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of PTGS2 protein]
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Organoselenium Compounds results in decreased activity of PTGS2 protein
CTD PMID:18538761 PMID:20883674 PMID:31400342 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein] CTD PMID:18538761 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SGK1 mRNA CTD PMID:25167922 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein] CTD PMID:25301743 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SLC2A1 mRNA CTD PMID:25167922 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SLC2A3 mRNA CTD PMID:25167922 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SQSTM1 mRNA CTD PMID:25167922 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of TNF mRNA]
Organoselenium Compounds results in decreased expression of TNF protein
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:18538761 PMID:20883674 PMID:31400342 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of TRIB3 mRNA CTD PMID:25167922 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of TXNRD1 mRNA CTD PMID:25167922 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of VEGFA mRNA CTD PMID:25167922 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of VEGFC mRNA CTD PMID:25167922 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
ebselen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16757516 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO ebselen inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA] CTD PMID:11133813 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
EXP
ISO
Dithiothreitol inhibits the reaction [ebselen results in decreased activity of ALAD protein]
ebselen inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]
CTD PMID:14630126 PMID:17624921 PMID:23933410 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity ISO ebselen results in decreased activity of ALOX5 protein CTD PMID:7590103 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of BAX protein] CTD PMID:30558456 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein] CTD PMID:30558456 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein]
ebselen results in increased activity of CASP3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; ebselen inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
CTD PMID:21300091 PMID:23649643 PMID:25068500 PMID:30558456 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein]
ebselen inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]
CTD PMID:18629305 PMID:23649643 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP ebselen results in increased activity of CAT protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:27282967 PMID:30558456 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO ebselen results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cs citrate synthase multiple interactions ISO
EXP
ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]
ebselen inhibits the reaction [Cisplatin results in decreased activity of CS protein]
CTD PMID:27385396 PMID:32860823 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:11903743 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP ebselen results in increased phosphorylation of EIF2S1 protein CTD PMID:27282967 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO ebselen binds to and results in decreased activity of EPHX2 protein CTD PMID:23219563 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of FOS protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of FOS protein] CTD PMID:14572605 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP ebselen inhibits the reaction [Cisplatin results in increased activity of G6PC1 protein] CTD PMID:32860823 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gck glucokinase multiple interactions ISO [ebselen co-treated with Glucose] results in increased activity of GCK protein CTD PMID:23795780 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gfap glial fibrillary acidic protein increases phosphorylation EXP ebselen results in increased phosphorylation of GFAP protein CTD PMID:27282967 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]; ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 protein] CTD PMID:12958040 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
ebselen inhibits the reaction [Methylmercury Compounds results in decreased activity of GPX1 protein]
CTD PMID:23795780 PMID:28383113 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
EXP ebselen results in increased activity of GSR protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD PMID:27282967 PMID:30558456 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein] CTD PMID:8147899 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]; ebselen binds to and results in decreased activity of GSTA3 protein CTD PMID:8147899 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP ebselen binds to and results in decreased activity of GSTP1 protein CTD PMID:8147899 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]] CTD PMID:19374849 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [ebselen affects the abundance of Reactive Oxygen Species] which results in decreased expression of HMOX1 protein; [ebselen affects the abundance of Reactive Oxygen Species] which results in increased activity of HMOX1 protein CTD PMID:16959961 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO ebselen results in increased expression of HPGDS mRNA CTD PMID:21669866 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Ifng interferon gamma multiple interactions ISO ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:12794164 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il6 interleukin 6 multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of IL6 protein] CTD PMID:30558456 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen results in increased activity of MAPK1 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen analog results in increased phosphorylation of MAPK1 protein; ebselen results in increased phosphorylation of MAPK1 protein
CTD PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
ebselen results in increased activity of MAPK3 protein
ebselen analog results in increased phosphorylation of MAPK3 protein; ebselen results in increased phosphorylation of MAPK3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation EXP ebselen results in increased phosphorylation of MAPK9 protein CTD PMID:27282967 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP13 mRNA] CTD PMID:11903743 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Ngf nerve growth factor multiple interactions ISO ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO
EXP
ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]
ebselen results in decreased activity of NOS2 protein
CTD PMID:7590103 PMID:12794164 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity EXP ebselen results in decreased activity of NQO1 protein CTD PMID:7590103 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO [ebselen co-treated with Glucose] results in increased expression of PDX1 protein CTD PMID:23795780 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 decreases activity ISO ebselen results in decreased activity of PHOSPHO1 protein CTD PMID:17227223 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of RELA protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of RELA protein] CTD PMID:14572605 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:16984886 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO
EXP
[ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein
ebselen inhibits the reaction [Cisplatin results in increased expression of SLC2A2 protein]
CTD PMID:23795780 PMID:32860823 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:21131394 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Sod1 superoxide dismutase 1 decreases response to substance
multiple interactions
ISO ebselen results in decreased susceptibility to SOD1 protein mutant form
ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:16702190 PMID:23795780 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP ebselen inhibits the reaction [Cisplatin results in increased activity of TAT protein] CTD PMID:32860823 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]
ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD PMID:11903743 PMID:16757516 PMID:21131394 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:11903743 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of TNF protein] CTD PMID:30558456 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO ebselen results in increased expression of and results in increased activity of TXNRD1 protein CTD PMID:28383113 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [ebselen co-treated with Glucose] results in decreased expression of UCP2 protein CTD PMID:23795780 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Xbp1 X-box binding protein 1 increases phosphorylation EXP ebselen results in increased phosphorylation of XBP1 protein CTD PMID:27282967 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO ebselen inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:60,431,673...60,476,438
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
methylseleninic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
affects expression
decreases expression
ISO AR protein inhibits the reaction [methylselenic acid results in decreased expression of ABCC4 mRNA]
methylselenic acid affects the expression of ABCC4 mRNA
CTD PMID:14617803 PMID:16020662 PMID:18548127 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Acp3 acid phosphatase 3 affects expression ISO methylselenic acid affects the expression of ACP3 mRNA CTD PMID:14617803 NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 affects expression
decreases expression
ISO methylselenic acid affects the expression of ACSL3 mRNA
methylselenic acid results in decreased expression of ACSL3 mRNA
CTD PMID:14617803 PMID:18548127 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO methylselenic acid results in increased expression of ACTA2 mRNA CTD PMID:18548127 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression ISO methylselenic acid results in increased expression of ACTG2 mRNA CTD PMID:18548127 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO methylselenic acid results in increased expression of ADAM22 mRNA CTD PMID:18548127 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
JBrowse link
G Add3 adducin 3 increases expression ISO methylselenic acid results in increased expression of ADD3 mRNA CTD PMID:12517777 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 increases expression ISO methylselenic acid results in increased expression of ADGRL3 mRNA CTD PMID:18548127 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO methylselenic acid results in increased expression of AHR mRNA CTD PMID:18548127 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO methylselenic acid results in increased expression of AKAP12 mRNA CTD PMID:18548127 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Akap2 A-kinase anchoring protein 2 increases expression ISO methylselenic acid results in increased expression of PALM2AKAP2 mRNA CTD PMID:18548127 NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO methylselenic acid results in increased expression of AKR1B1 mRNA CTD PMID:18548127 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases response to substance
decreases phosphorylation
ISO [methylselenic acid results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]
AKT1 protein results in decreased susceptibility to methylselenic acid
CTD PMID:15845651 PMID:17339365 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO methylselenic acid results in decreased expression of AKT2 mRNA CTD PMID:11830524 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alad aminolevulinate dehydratase increases expression ISO methylselenic acid results in increased expression of ALAD mRNA CTD PMID:18548127 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase decreases expression ISO methylselenic acid results in decreased expression of ALG3 mRNA CTD PMID:18548127 NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912
JBrowse link
G Alg8 ALG8, alpha-1,3-glucosyltransferase decreases expression ISO methylselenic acid results in decreased expression of ALG8 mRNA CTD PMID:18548127 NCBI chr 1:151,684,344...151,704,310
Ensembl chr 1:151,684,396...151,704,302
JBrowse link
G Amt aminomethyltransferase increases expression ISO methylselenic acid results in increased expression of AMT mRNA CTD PMID:18548127 NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126
JBrowse link
G Ank2 ankyrin 2 increases expression ISO methylselenic acid results in increased expression of ANK2 mRNA CTD PMID:18548127 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ank3 ankyrin 3 decreases expression ISO methylselenic acid results in decreased expression of ANK3 mRNA CTD PMID:18548127 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Apod apolipoprotein D affects expression ISO methylselenic acid affects the expression of APOD mRNA CTD PMID:14617803 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Ar androgen receptor affects response to substance
increases degradation
decreases expression
decreases activity
multiple interactions
ISO AR protein affects the susceptibility to methylselenic acid
methylselenic acid results in increased degradation of AR mRNA; methylselenic acid results in increased degradation of AR protein
methylselenic acid results in decreased expression of AR mRNA; methylselenic acid results in decreased expression of AR protein
methylselenic acid results in decreased activity of AR protein
AR protein inhibits the reaction [methylselenic acid results in decreased expression of ABCC4 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A1 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of KLK2 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of KLK3 mRNA]; methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 promoter]]; Superoxides promotes the reaction [methylselenic acid results in decreased expression of AR protein]
CTD PMID:14617803 PMID:15141018 PMID:16020662 PMID:16648561 PMID:16928829 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO methylselenic acid results in increased expression of ARHGEF2 mRNA CTD PMID:18548127 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression ISO methylselenic acid results in increased expression of ARL4A mRNA CTD PMID:18548127 NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO methylselenic acid results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:11830524 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf3 activating transcription factor 3 affects expression ISO methylselenic acid affects the expression of ATF3 mRNA CTD PMID:14617803 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO methylselenic acid results in decreased expression of ATF5 mRNA CTD PMID:12517777 PMID:18548127 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO methylselenic acid results in increased cleavage of and results in increased activity of ATF6 protein CTD PMID:16205645 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO methylselenic acid results in increased expression of ATP2A2 mRNA CTD PMID:18548127 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO methylselenic acid results in increased expression of ATP2B4 mRNA CTD PMID:18548127 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Aurka aurora kinase A affects expression
decreases expression
ISO methylselenic acid affects the expression of AURKA mRNA
methylselenic acid results in decreased expression of AURKA mRNA
CTD PMID:12517777 PMID:14617803 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 affects expression ISO methylselenic acid affects the expression of B4GALT1 mRNA CTD PMID:14617803 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO methylselenic acid results in increased expression of BACH1 mRNA CTD PMID:12517777 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression EXP methylselenic acid affects the expression of BAX protein CTD PMID:12017302 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO methylselenic acid results in increased expression of BBC3 mRNA CTD PMID:28161410 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression EXP methylselenic acid affects the expression of BCL2 protein CTD PMID:12017302 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO methylselenic acid results in increased expression of BCL2A1 mRNA CTD PMID:11830524 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions
increases cleavage
increases expression
ISO BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; Tamoxifen promotes the reaction [methylselenic acid results in increased cleavage of BCL2L11 protein]
methylselenic acid results in increased expression of BCL2L11 mRNA; methylselenic acid results in increased expression of BCL2L11 protein
CTD PMID:17339365 PMID:18790785 PMID:28161410 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects expression ISO methylselenic acid affects the expression of BIRC2 mRNA CTD PMID:14617803 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects expression ISO methylselenic acid affects the expression of BIRC3 mRNA CTD PMID:14617803 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of BIRC5 protein; methylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter]
methylselenic acid results in decreased expression of BIRC5 mRNA; methylselenic acid results in decreased expression of BIRC5 protein
CTD PMID:12517777 PMID:17876054 PMID:18444175 PMID:18567002 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO methylselenic acid results in increased expression of BMP4 mRNA CTD PMID:12517777 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO methylselenic acid results in increased expression of BRCA2 mRNA CTD PMID:12517777 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO methylselenic acid results in increased expression of BTG3 mRNA CTD PMID:18548127 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B affects expression ISO methylselenic acid affects the expression of BUB1B mRNA CTD PMID:14617803 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C1qbp complement C1q binding protein decreases expression ISO methylselenic acid results in decreased expression of C1QBP mRNA CTD PMID:18548127 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G Cadm1 cell adhesion molecule 1 affects expression ISO methylselenic acid affects the expression of CADM1 mRNA CTD PMID:14617803 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Calm1 calmodulin 1 increases expression ISO methylselenic acid results in increased expression of CALM1 mRNA CTD PMID:18548127 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO methylselenic acid results in increased expression of CAMK2G mRNA CTD PMID:18548127 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases expression ISO methylselenic acid results in increased expression of CAMK4 mRNA CTD PMID:12517777 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression ISO methylselenic acid results in decreased expression of CAPZA1 mRNA CTD PMID:18548127 NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480
JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage
ISO HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein] CTD PMID:16204082 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO methylselenic acid results in increased cleavage of and results in increased activity of CASP3 protein
methylselenic acid results in increased cleavage of CASP3 protein
CTD PMID:19276161 PMID:28161410 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases cleavage ISO methylselenic acid results in increased cleavage of CASP4 protein CTD PMID:28161410 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
ISO methylselenic acid results in increased cleavage of CASP7 protein
Acetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]; Sodium Selenite inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; Tamoxifen promotes the reaction [methylselenic acid results in increased cleavage of CASP7 protein]
CTD PMID:16204082 PMID:18790785 PMID:28161410 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP8 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP8 protein
[methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP8 protein
CTD PMID:18444175 PMID:18790785 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP9 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]; methylselenic acid results in increased cleavage of and results in increased activity of CASP9 protein
[methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP9 protein
methylselenic acid results in increased expression of CASP9 mRNA
CTD PMID:12517777 PMID:17339365 PMID:18444175 PMID:18790785 PMID:28161410 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cast calpastatin increases expression ISO methylselenic acid results in increased expression of CAST mRNA CTD PMID:18548127 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cbx7 chromobox 7 increases expression ISO methylselenic acid results in increased expression of CBX7 mRNA CTD PMID:18548127 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cck cholecystokinin increases expression ISO methylselenic acid results in increased expression of CCK mRNA CTD PMID:18548127 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO methylselenic acid results in decreased expression of CCNA2 mRNA CTD PMID:12517777 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO methylselenic acid results in decreased expression of CCNB1 mRNA; methylselenic acid results in decreased expression of CCNB1 protein CTD PMID:11830524 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 affects expression
decreases expression
multiple interactions
ISO
EXP
methylselenic acid affects the expression of CCND1 mRNA
methylselenic acid affects the expression of CCND1 protein
methylselenic acid results in decreased expression of CCND1 mRNA
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of CCND1 protein; KLF4 protein affects the reaction [methylselenic acid results in decreased expression of CCND1 mRNA]; methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]
CTD PMID:11830524 PMID:12017302 PMID:17847021 PMID:18314491 PMID:18444175 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO methylselenic acid results in decreased expression of CCNE2 mRNA CTD PMID:12517777 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd14 CD14 molecule decreases expression ISO methylselenic acid results in decreased expression of CD14 mRNA CTD PMID:18548127 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO methylselenic acid results in decreased expression of CD44 mRNA CTD PMID:12517777 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc14b cell division cycle 14B affects expression ISO methylselenic acid affects the expression of CDC14B mRNA CTD PMID:14617803 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdc20 cell division cycle 20 affects expression ISO methylselenic acid affects the expression of CDC20 mRNA CTD PMID:14617803 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25a cell division cycle 25A affects expression
decreases expression
ISO methylselenic acid affects the expression of CDC25A mRNA
methylselenic acid results in decreased expression of CDC25A mRNA; methylselenic acid results in decreased expression of CDC25A protein
CTD PMID:11830524 PMID:14617803 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO methylselenic acid results in decreased expression of CDC25C mRNA CTD PMID:11830524 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO methylselenic acid results in decreased expression of CDC42 mRNA CTD PMID:11830524 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression ISO methylselenic acid results in increased expression of CDC42EP3 mRNA CTD PMID:18548127 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of CDC6 mRNA
methylselenic acid affects the expression of CDC6 mRNA
CTD PMID:11830524 PMID:14617803 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdh15 cadherin 15 increases expression ISO methylselenic acid results in increased expression of CDH15 mRNA CTD PMID:12517777 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
JBrowse link
G Cdh7 cadherin 7 increases expression ISO methylselenic acid results in increased expression of CDH7 mRNA CTD PMID:12517777 NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
ISO HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK1 protein]
methylselenic acid results in decreased expression of CDK1 mRNA; methylselenic acid results in decreased expression of CDK1 protein
CTD PMID:11830524 PMID:12517777 PMID:16205645 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression ISO methylselenic acid results in decreased expression of CDK10 mRNA CTD PMID:11830524 NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
JBrowse link
G Cdk16 cyclin-dependent kinase 16 decreases expression ISO methylselenic acid results in decreased expression of CDK16 mRNA CTD PMID:12517777 NCBI chr  X:1,492,814...1,504,309
Ensembl chr  X:1,492,814...1,504,148
JBrowse link
G Cdk18 cyclin-dependent kinase 18 increases expression ISO methylselenic acid results in increased expression of CDK18 mRNA CTD PMID:18548127 NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases expression
ISO HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]
methylselenic acid results in decreased expression of CDK2 mRNA; methylselenic acid results in decreased expression of CDK2 protein
CTD PMID:12517777 PMID:16205645 PMID:17847021 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
decreases expression
ISO methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]
methylselenic acid results in decreased expression of CDK4 mRNA
CTD PMID:11830524 PMID:12517777 PMID:17847021 PMID:18548127 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression ISO methylselenic acid results in increased expression of CDK5 mRNA CTD PMID:11830524 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO methylselenic acid promotes the reaction [CDKN2A protein binds to CDK6 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK6 protein] CTD PMID:17847021 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkl1 cyclin dependent kinase like 1 decreases expression ISO methylselenic acid results in decreased expression of CDKL1 mRNA CTD PMID:11830524 NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects expression
increases expression
ISO
EXP
DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in increased expression of and results in decreased degradation of CDKN1A protein
methylselenic acid affects the expression of CDKN1A protein
methylselenic acid results in increased expression of CDKN1A mRNA; methylselenic acid results in increased expression of CDKN1A protein
methylselenic acid affects the expression of CDKN1A mRNA
CTD PMID:12017302 PMID:12517777 PMID:14617803 PMID:16205645 PMID:17847021 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
affects expression
increases expression
ISO
EXP
KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1B mRNA]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]
methylselenic acid affects the expression of CDKN1B protein
methylselenic acid results in increased expression of CDKN1B mRNA; methylselenic acid results in increased expression of CDKN1B protein
CTD PMID:12017302 PMID:17847021 PMID:18314491 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression
affects expression
ISO methylselenic acid results in increased expression of CDKN1C mRNA
methylselenic acid affects the expression of CDKN1C mRNA
CTD PMID:14617803 PMID:18548127 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
increases expression
ISO methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid promotes the reaction [CDKN2A protein binds to CDK6 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK6 protein]
methylselenic acid results in increased expression of CDKN2A protein
CTD PMID:17847021 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D affects expression
increases expression
ISO methylselenic acid affects the expression of CDKN2D mRNA
methylselenic acid results in increased expression of CDKN2D mRNA
CTD PMID:12517777 PMID:14617803 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Cenpa centromere protein A affects expression ISO methylselenic acid affects the expression of CENPA mRNA CTD PMID:14617803 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpf centromere protein F decreases expression ISO methylselenic acid results in decreased expression of CENPF mRNA CTD PMID:12517777 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of CFLAR protein CTD PMID:18444175 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO methylselenic acid results in decreased expression of CHAF1A mRNA CTD PMID:12517777 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO methylselenic acid results in increased expression of CHEK2 mRNA CTD PMID:12517777 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Clu clusterin affects expression ISO methylselenic acid affects the expression of CLU mRNA CTD PMID:14617803 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnpy2 canopy FGF signaling regulator 2 decreases expression ISO methylselenic acid results in decreased expression of CNPY2 mRNA CTD PMID:18548127 NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519
JBrowse link
G Col16a1 collagen type XVI alpha 1 chain increases expression ISO methylselenic acid results in increased expression of COL16A1 mRNA CTD PMID:18548127 NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:142,388,426...142,442,825
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO methylselenic acid results in increased expression of COL6A1 mRNA CTD PMID:18548127 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Coro1a coronin 1A increases expression ISO methylselenic acid results in increased expression of CORO1A mRNA CTD PMID:12517777 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO methylselenic acid results in increased expression of CRABP2 mRNA CTD PMID:18548127 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO methylselenic acid results in increased expression of CREB1 mRNA CTD PMID:12517777 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 decreases expression ISO methylselenic acid results in decreased expression of CREB3L1 mRNA CTD PMID:18548127 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 affects expression ISO methylselenic acid affects the expression of CREB3L4 mRNA CTD PMID:14617803 NCBI chr 2:175,690,340...175,696,084
Ensembl chr 2:175,690,335...175,695,932
JBrowse link
G Cryab crystallin, alpha B increases expression ISO methylselenic acid results in increased expression of CRYAB mRNA CTD PMID:18548127 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression ISO methylselenic acid results in increased expression of CSRP1 mRNA CTD PMID:18548127 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Ctsk cathepsin K increases expression ISO methylselenic acid results in increased expression of CTSK mRNA CTD PMID:18548127 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cul1 cullin 1 increases expression ISO methylselenic acid results in increased expression of CUL1 mRNA CTD PMID:18548127 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression ISO methylselenic acid results in increased expression of CYLD mRNA CTD PMID:18548127 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of DDIT3 protein]
methylselenic acid results in increased expression of DDIT3 mRNA; methylselenic acid results in increased expression of DDIT3 protein
CTD PMID:11830524 PMID:12517777 PMID:16204082 PMID:16205645 PMID:19276161 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression ISO methylselenic acid results in decreased expression of DEAF1 mRNA CTD PMID:18548127 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions
decreases expression
ISO AR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA] CTD PMID:16020662 PMID:18548127 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO methylselenic acid results in decreased expression of DHFR mRNA CTD PMID:12517777 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO methylselenic acid results in increased expression of DIXDC1 mRNA CTD PMID:18548127 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression ISO methylselenic acid results in decreased expression of DKC1 mRNA CTD PMID:18548127
G Dlc1 DLC1 Rho GTPase activating protein increases expression ISO methylselenic acid results in increased expression of DLC1 mRNA CTD PMID:12517777 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression ISO methylselenic acid results in increased expression of DNAJB5 mRNA CTD PMID:18548127 NCBI chr 5:57,176,840...57,185,492
Ensembl chr 5:57,176,845...57,185,490
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 affects expression ISO methylselenic acid affects the expression of DNAJB9 mRNA CTD PMID:14617803 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO methylselenic acid results in decreased expression of DNPH1 mRNA CTD PMID:18548127 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases expression ISO methylselenic acid results in increased expression of DPYD mRNA CTD PMID:18548127 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO methylselenic acid results in increased expression of DPYSL2 mRNA CTD PMID:18548127 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dtna dystrobrevin, alpha increases expression ISO methylselenic acid results in increased expression of DTNA mRNA CTD PMID:18548127 NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression ISO methylselenic acid results in decreased expression of DTYMK mRNA CTD PMID:12517777 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO methylselenic acid results in increased expression of DUSP10 mRNA CTD PMID:12517777 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression ISO methylselenic acid results in increased expression of DVL3 mRNA CTD PMID:18548127 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 increases expression ISO methylselenic acid results in increased expression of DYNC1I1 mRNA CTD PMID:18548127 NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
JBrowse link
G E2f1 E2F transcription factor 1 affects expression
multiple interactions
decreases expression
ISO methylselenic acid affects the expression of E2F1 mRNA
methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein]
methylselenic acid results in decreased expression of E2F1 mRNA; methylselenic acid results in decreased expression of E2F1 protein
CTD PMID:11830524 PMID:14617803 PMID:17847021 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO methylselenic acid results in decreased expression of E2F5 mRNA CTD PMID:11830524 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 decreases expression ISO methylselenic acid results in decreased expression of ECI1 mRNA CTD PMID:18548127 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO methylselenic acid results in increased expression of ECM2 mRNA CTD PMID:18548127 NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
JBrowse link
G Ednra endothelin receptor type A increases expression ISO methylselenic acid results in increased expression of EDNRA mRNA CTD PMID:18548127 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO methylselenic acid results in increased expression of EDNRB mRNA CTD PMID:18548127 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO methylselenic acid results in increased expression of EFEMP2 mRNA CTD PMID:18548127 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414
JBrowse link
G Egr1 early growth response 1 increases expression ISO methylselenic acid results in increased expression of EGR1 mRNA CTD PMID:11172735 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases phosphorylation
ISO HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2A protein] CTD PMID:16204082 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein]; methylselenic acid results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:16204082 PMID:16205645 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 decreases expression ISO methylselenic acid results in decreased expression of EIF4G2 mRNA CTD PMID:12517777 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression
affects expression
ISO methylselenic acid results in increased expression of ELF3 mRNA
methylselenic acid affects the expression of ELF3 mRNA
CTD PMID:12517777 PMID:14617803 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
JBrowse link
G Eno2 enolase 2 increases expression ISO methylselenic acid results in increased expression of ENO2 mRNA CTD PMID:18548127 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 increases expression ISO methylselenic acid results in increased expression of EPB41L2 mRNA CTD PMID:18548127 NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO methylselenic acid results in increased expression of EPS8 mRNA CTD PMID:18548127 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression ISO methylselenic acid results in increased expression of ERCC1 mRNA CTD PMID:12517777 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO [methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 mRNA; [methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 protein; methylselenic acid inhibits the reaction [Estradiol binds to ESR1 protein]; methylselenic acid results in decreased expression of and results in decreased activity of ESR1 protein
methylselenic acid results in decreased expression of ESR1 mRNA; methylselenic acid results in decreased expression of ESR1 protein
CTD PMID:15833885 PMID:16093440 PMID:16155795 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases expression
affects expression
ISO methylselenic acid results in increased expression of ESR2 mRNA
methylselenic acid affects the expression of ESR2 mRNA
CTD PMID:15833885 PMID:16928829 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression ISO methylselenic acid results in increased expression of ETV5 mRNA CTD PMID:18548127 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
JBrowse link
G Etv6 ETS variant transcription factor 6 increases expression ISO methylselenic acid results in increased expression of ETV6 mRNA CTD PMID:18548127 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Ext1 exostosin glycosyltransferase 1 increases expression ISO methylselenic acid results in increased expression of EXT1 mRNA CTD PMID:18548127 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression ISO methylselenic acid results in increased expression of FAM107A mRNA CTD PMID:18548127 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
JBrowse link
G Fbxl8 F-box and leucine-rich repeat protein 8 increases expression ISO methylselenic acid results in increased expression of FBXL8 mRNA CTD PMID:18548127 NCBI chr19:33,142,653...33,147,268
Ensembl chr19:33,142,715...33,147,262
JBrowse link
G Fermt2 FERM domain containing kindlin 2 increases expression ISO methylselenic acid results in increased expression of FERMT2 mRNA CTD PMID:18548127 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression ISO methylselenic acid results in increased expression of FEZ1 mRNA CTD PMID:18548127 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO methylselenic acid results in decreased expression of FGF2 mRNA CTD PMID:12517777 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO methylselenic acid results in increased expression of FHL2 mRNA CTD PMID:18548127 NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression ISO methylselenic acid results in decreased expression of FKBP4 mRNA CTD PMID:18548127 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 affects expression ISO methylselenic acid affects the expression of FKBP5 mRNA CTD PMID:14617803 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flnc filamin C increases expression ISO methylselenic acid results in increased expression of FLNC mRNA CTD PMID:18548127 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
JBrowse link
G Fn1 fibronectin 1 affects expression ISO methylselenic acid affects the expression of FN1 mRNA CTD PMID:14617803 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fnbp1 formin binding protein 1 increases expression ISO methylselenic acid results in increased expression of FNBP1 mRNA CTD PMID:18548127 NCBI chr 3:14,316,011...14,386,704
Ensembl chr 3:14,309,640...14,424,881
JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO methylselenic acid results in decreased expression of FOXA1 mRNA CTD PMID:12517777 PMID:18548127 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO methylselenic acid results in decreased phosphorylation of and results in increased activity of FOXO3 protein CTD PMID:17339365 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO methylselenic acid results in increased expression of FYN mRNA CTD PMID:18548127 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO methylselenic acid results in increased expression of GABARAPL1 mRNA CTD PMID:18548127 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO methylselenic acid results in increased expression of GADD45A mRNA CTD PMID:12517777 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO methylselenic acid results in decreased expression of GALNT1 mRNA CTD PMID:18548127 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
JBrowse link
G Gas1 growth arrest-specific 1 increases expression ISO methylselenic acid results in increased expression of GAS1 mRNA CTD PMID:18548127 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gatd3a glutamine amidotransferase class 1 domain containing 3A decreases expression ISO methylselenic acid results in decreased expression of GATD3 mRNA CTD PMID:18548127 NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO methylselenic acid results in increased expression of GBP2 mRNA CTD PMID:18548127 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO methylselenic acid results in increased expression of GJA1 mRNA CTD PMID:18548127 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gpr161 G protein-coupled receptor 161 increases expression ISO methylselenic acid results in increased expression of GPR161 mRNA CTD PMID:18548127 NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613
JBrowse link
G Gpr37 G protein-coupled receptor 37 increases expression ISO methylselenic acid results in increased expression of GPR37 mRNA CTD PMID:12517777 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO methylselenic acid results in increased expression of GRK5 mRNA CTD PMID:18548127 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
ISO methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]
methylselenic acid results in decreased phosphorylation of GSK3B protein
CTD PMID:17339365 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin increases expression ISO methylselenic acid results in increased expression of GSN mRNA CTD PMID:18548127 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 decreases expression ISO methylselenic acid results in decreased expression of GTF3C1 mRNA CTD PMID:18548127 NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 affects expression
decreases expression
multiple interactions
ISO methylselenic acid affects the expression of GUCY1A1 mRNA
methylselenic acid results in decreased expression of GUCY1A1 mRNA
AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A1 mRNA]
CTD PMID:14617803 PMID:16020662 PMID:18548127 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G H1f0 H1.0 linker histone affects expression ISO methylselenic acid affects the expression of H1-0 mRNA CTD PMID:14617803 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G Habp4 hyaluronan binding protein 4 increases expression ISO methylselenic acid results in increased expression of HABP4 mRNA CTD PMID:18548127 NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 decreases expression ISO methylselenic acid results in decreased expression of HACD2 mRNA CTD PMID:18548127 NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889
JBrowse link
G Heph hephaestin increases expression ISO methylselenic acid results in increased expression of HEPH mRNA CTD PMID:18548127 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression ISO methylselenic acid results in decreased expression of H2AC8 mRNA CTD PMID:18548127 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 decreases expression ISO methylselenic acid results in decreased expression of H2AC18 mRNA CTD PMID:18548127 NCBI chr 2:183,808,398...183,808,922 JBrowse link
G Hmgn4 high mobility group nucleosomal binding domain 4 increases expression ISO methylselenic acid results in increased expression of HMGN4 mRNA CTD PMID:18548127 NCBI chr 3:99,990,743...99,991,093
Ensembl chr 3:99,990,743...99,991,003
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B decreases expression ISO methylselenic acid results in decreased expression of HNRNPAB mRNA CTD PMID:18548127 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Hoxa9 homeobox A9 decreases expression ISO methylselenic acid results in decreased expression of HOXA9 mRNA CTD PMID:18548127 NCBI chr 4:81,323,235...81,329,344 JBrowse link
G Hoxd8 homeobox D8 increases expression ISO methylselenic acid results in increased expression of HOXD8 mRNA CTD PMID:12517777 NCBI chr 3:59,607,864...59,610,358 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO methylselenic acid results in increased expression of HPGD mRNA; methylselenic acid results in increased expression of HPGD protein CTD PMID:25187657 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO methylselenic acid results in increased expression of HPGDS mRNA CTD PMID:21669866 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression
multiple interactions
ISO methylselenic acid results in increased expression of HSP90B1 protein
HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSP90B1 protein]
CTD PMID:16204082 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO methylselenic acid results in increased expression of HSPA4L mRNA CTD PMID:18548127 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK1 protein]; HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein]; HSPA5 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of DDIT3 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSP90B1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSPA5 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein]; methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]
methylselenic acid results in increased expression of HSPA5 mRNA; methylselenic acid results in increased expression of HSPA5 protein
CTD PMID:16204082 PMID:16205645 PMID:28161410 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO methylselenic acid results in decreased expression of ID1 mRNA CTD PMID:12517777 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id2 inhibitor of DNA binding 2 affects expression ISO methylselenic acid affects the expression of ID2 mRNA CTD PMID:14617803 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression
increases expression
ISO methylselenic acid results in decreased expression of ID3 mRNA
methylselenic acid results in increased expression of ID3 mRNA
CTD PMID:12517777 PMID:18548127 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ids iduronate 2-sulfatase increases expression ISO methylselenic acid results in increased expression of IDS mRNA CTD PMID:18548127 NCBI chr  X:149,025,977...149,046,639
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 decreases expression ISO methylselenic acid results in decreased expression of IFRD2 mRNA CTD PMID:18548127 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO methylselenic acid results in increased expression of IGF1 mRNA CTD PMID:11830524 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igsf3 immunoglobulin superfamily, member 3 affects expression ISO methylselenic acid affects the expression of IGSF3 mRNA CTD PMID:14617803 NCBI chr 2:188,811,394...188,899,645
Ensembl chr 2:188,811,380...188,899,645
JBrowse link
G Ing1 inhibitor of growth family, member 1 affects expression ISO methylselenic acid affects the expression of ING1 mRNA CTD PMID:14617803 NCBI chr16:77,937,276...77,945,320
Ensembl chr16:77,937,279...77,946,264
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B affects expression ISO methylselenic acid affects the expression of INPP4B mRNA CTD PMID:14617803 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Ipo8 importin 8 increases expression ISO methylselenic acid results in increased expression of IPO8 mRNA CTD PMID:12517777 NCBI chr 4:181,729,216...181,793,673 JBrowse link
G Irf1 interferon regulatory factor 1 affects expression ISO methylselenic acid affects the expression of IRF1 mRNA CTD PMID:14617803 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO methylselenic acid results in increased expression of ITGA3 mRNA CTD PMID:18548127 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO methylselenic acid results in decreased expression of ITGB1 mRNA CTD PMID:11172735 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein decreases expression ISO methylselenic acid results in decreased expression of ITGB3BP mRNA CTD PMID:12517777 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO methylselenic acid results in decreased expression of ITGB4 mRNA CTD PMID:12517777 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO methylselenic acid results in decreased expression of ITGB5 mRNA CTD PMID:12517777 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO methylselenic acid results in increased expression of ITPR1 mRNA CTD PMID:18548127 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Jak1 Janus kinase 1 affects expression
increases expression
ISO methylselenic acid affects the expression of JAK1 mRNA
methylselenic acid results in increased expression of JAK1 mRNA
CTD PMID:14617803 PMID:18548127 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
affects expression
ISO methylselenic acid results in decreased expression of JUN protein
methylselenic acid affects the expression of JUN mRNA
CTD PMID:11830524 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO methylselenic acid results in decreased expression of JUNB mRNA CTD PMID:12517777 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression ISO methylselenic acid results in increased expression of KCNAB1 mRNA CTD PMID:18548127 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 increases expression ISO methylselenic acid results in increased expression of KCNH2 mRNA CTD PMID:18548127 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 increases expression ISO methylselenic acid results in increased expression of KCNJ8 mRNA CTD PMID:18548127 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 decreases expression ISO methylselenic acid results in decreased expression of KDELR2 mRNA CTD PMID:18548127 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO methylselenic acid results in decreased expression of KIF11 mRNA CTD PMID:12517777 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO methylselenic acid results in decreased expression of KIF20B mRNA CTD PMID:12517777 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions
increases expression
increases activity
affects expression
ISO KLF4 protein affects the reaction [methylselenic acid results in decreased expression of CCND1 mRNA]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1B mRNA]
methylselenic acid results in increased expression of KLF4 mRNA
methylselenic acid results in increased activity of KLF4 protein
methylselenic acid affects the expression of KLF4 mRNA
CTD PMID:14617803 PMID:18314491 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klhl2 kelch-like family member 2 affects expression ISO methylselenic acid affects the expression of KLHL2 mRNA CTD PMID:14617803 NCBI chr16:24,860,763...24,973,348
Ensembl chr16:24,860,667...24,973,341
JBrowse link
G Krt15 keratin 15 increases expression ISO methylselenic acid results in increased expression of KRT15 mRNA CTD PMID:18548127 NCBI chr10:85,066,797...85,070,614 JBrowse link
G Krt20 keratin 20 increases expression ISO methylselenic acid results in increased expression of KRT20 mRNA CTD PMID:12517777 NCBI chr10:84,384,802...84,394,107
Ensembl chr10:84,384,802...84,394,107
JBrowse link
G Lage3 L antigen family, member 3 decreases expression ISO methylselenic acid results in decreased expression of LAGE3 mRNA CTD PMID:18548127 NCBI chr  X:152,138,209...152,139,632
Ensembl chr  X:152,138,218...152,139,632
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression ISO methylselenic acid results in increased expression of LAMA4 mRNA CTD PMID:18548127 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO methylselenic acid results in increased expression of LAMB3 mRNA CTD PMID:18548127 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
JBrowse link
G Lmnb2 lamin B2 decreases expression ISO methylselenic acid results in decreased expression of LMNB2 mRNA CTD PMID:12517777 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G LOC684932 similar to Zinc finger protein 75 increases expression ISO methylselenic acid results in increased expression of ZNF75D mRNA CTD PMID:12517777 NCBI chr  X:134,035,116...134,053,765
Ensembl chr  X:134,036,143...134,051,519
JBrowse link
G Lypla1 lysophospholipase 1 decreases expression ISO methylselenic acid results in decreased expression of LYPLA1 mRNA CTD PMID:18548127 NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746
JBrowse link
G Maea macrophage erythroblast attacher, E3 ubiquitin ligase decreases expression ISO methylselenic acid results in decreased expression of MAEA mRNA CTD PMID:18548127 NCBI chr14:77,357,261...77,390,683
Ensembl chr14:77,357,264...77,390,671
JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO methylselenic acid results in increased expression of MAF mRNA CTD PMID:18548127 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Map1b microtubule-associated protein 1B affects expression
increases expression
ISO methylselenic acid affects the expression of MAP1B mRNA
methylselenic acid results in increased expression of MAP1B mRNA
CTD PMID:14617803 PMID:18548127 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression
increases expression
ISO methylselenic acid results in decreased expression of MAP2K1 mRNA
methylselenic acid results in increased expression of MAP2K1 mRNA
CTD PMID:11830524 PMID:12517777 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 increases expression ISO methylselenic acid results in increased expression of MAP2K5 mRNA CTD PMID:12517777 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO methylselenic acid results in increased phosphorylation of MAPK1 protein CTD PMID:15845651 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
increases phosphorylation
ISO methylselenic acid results in increased expression of MAPK3 mRNA
methylselenic acid results in increased phosphorylation of MAPK3 protein
CTD PMID:11830524 PMID:15845651 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO methylselenic acid results in increased expression of MAPK8 mRNA CTD PMID:12517777 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression ISO methylselenic acid results in decreased expression of MAPK9 mRNA CTD PMID:11830524 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO methylselenic acid results in increased expression of MAPRE2 mRNA CTD PMID:18548127 NCBI chr18:15,028,675...15,169,553 JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO methylselenic acid results in decreased expression of MAPT mRNA CTD PMID:12517777 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Maz MYC associated zinc finger protein decreases expression ISO methylselenic acid results in decreased expression of MAZ mRNA CTD PMID:12517777 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 increases expression ISO methylselenic acid results in increased expression of MBNL2 mRNA CTD PMID:18548127 NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO methylselenic acid results in decreased expression of MCCC2 mRNA CTD PMID:18548127 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 affects expression ISO methylselenic acid affects the expression of MCM2 mRNA CTD PMID:14617803 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO methylselenic acid results in decreased expression of MCM3 mRNA CTD PMID:12517777 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO methylselenic acid results in decreased expression of MCM5 mRNA CTD PMID:12517777 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of MCM6 mRNA
methylselenic acid affects the expression of MCM6 mRNA
CTD PMID:12517777 PMID:14617803 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO methylselenic acid results in decreased expression of MCM7 mRNA CTD PMID:12517777 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Me1 malic enzyme 1 increases expression ISO methylselenic acid results in increased expression of ME1 mRNA CTD PMID:18548127 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO methylselenic acid results in increased expression of MEF2C mRNA CTD PMID:18548127 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Men1 menin 1 affects expression ISO methylselenic acid affects the expression of MEN1 mRNA CTD PMID:14617803 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Micu2 mitochondrial calcium uptake 2 decreases expression ISO methylselenic acid results in decreased expression of MICU2 mRNA CTD PMID:18548127 NCBI chr15:32,064,872...32,146,874
Ensembl chr15:32,064,875...32,147,094
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO methylselenic acid results in increased expression of MITF mRNA CTD PMID:18548127 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO methylselenic acid results in decreased expression of MKI67 mRNA CTD PMID:12517777 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 decreases expression ISO methylselenic acid results in decreased expression of MRPL19 mRNA CTD PMID:18548127 NCBI chr 4:114,521,824...114,526,053
Ensembl chr 4:114,521,824...114,526,053
JBrowse link
G Mxd1 max dimerization protein 1 affects expression ISO methylselenic acid affects the expression of MXD1 mRNA CTD PMID:14617803 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO methylselenic acid results in increased expression of MXI1 mRNA CTD PMID:18548127 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO methylselenic acid results in decreased expression of MYBL2 mRNA CTD PMID:12517777 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression
multiple interactions
ISO methylselenic acid affects the expression of MYC mRNA
methylselenic acid inhibits the reaction [afimoxifene results in increased expression of MYC mRNA]; methylselenic acid inhibits the reaction [Estradiol results in increased expression of MYC mRNA]
CTD PMID:14617803 PMID:15833885 PMID:16093440 PMID:16155795 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myl9 myosin light chain 9 increases expression ISO methylselenic acid results in increased expression of MYL9 mRNA CTD PMID:18548127 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Myo10 myosin X decreases expression ISO methylselenic acid results in decreased expression of MYO10 mRNA CTD PMID:18548127 NCBI chr 2:76,100,962...76,304,164
Ensembl chr 2:76,100,987...76,303,030
JBrowse link
G Myrip myosin VIIA and Rab interacting protein decreases expression ISO methylselenic acid results in decreased expression of MYRIP mRNA CTD PMID:18548127 NCBI chr 8:120,017,843...120,184,821
Ensembl chr 8:120,017,524...120,183,833
JBrowse link
G Naaa N-acylethanolamine acid amidase decreases expression ISO methylselenic acid results in decreased expression of NAAA mRNA CTD PMID:18548127 NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA1 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA2 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone inhibits the reaction [NCOR1 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone inhibits the reaction [NCOR2 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ndrg1 N-myc downstream regulated 1 affects expression ISO methylselenic acid affects the expression of NDRG1 mRNA CTD PMID:14617803 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nebl nebulette increases expression ISO methylselenic acid results in increased expression of NEBL mRNA CTD PMID:18548127 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated affects expression ISO methylselenic acid affects the expression of NFIL3 mRNA CTD PMID:14617803 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO methylselenic acid results in decreased expression of NFKB1 mRNA CTD PMID:12517777 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nkx3-1 NK3 homeobox 1 affects expression ISO methylselenic acid affects the expression of NKX3-1 mRNA CTD PMID:14617803 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression ISO methylselenic acid results in decreased expression of NME1 mRNA CTD PMID:18548127 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 decreases expression ISO methylselenic acid results in decreased expression of NME4 mRNA CTD PMID:18548127 NCBI chr10:15,114,624...15,118,479 JBrowse link
G Nmi N-myc (and STAT) interactor decreases expression ISO methylselenic acid results in decreased expression of NMI mRNA CTD PMID:12517777 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity ISO methylselenic acid results in increased activity of NQO1 protein CTD PMID:14617803 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO methylselenic acid affects the expression of NR3C1 mRNA CTD PMID:16928829 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Oat ornithine aminotransferase increases expression ISO methylselenic acid results in increased expression of OAT mRNA CTD PMID:18548127 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Olfml2a olfactomedin-like 2A increases expression ISO methylselenic acid results in increased expression of OLFML2A mRNA CTD PMID:18548127 NCBI chr 3:22,688,562...22,717,745
Ensembl chr 3:22,688,598...22,717,909
JBrowse link
G Optn optineurin increases expression ISO methylselenic acid results in increased expression of OPTN mRNA CTD PMID:18548127 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of PARP1 protein; [Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]; SB 216763 inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein] CTD PMID:15845651 PMID:16204082 PMID:17339365 PMID:18444175 PMID:19276161 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Patz1 POZ (BTB) and AT hook containing zinc finger 1 decreases expression ISO methylselenic acid results in decreased expression of PATZ1 mRNA CTD PMID:12517777 NCBI chr14:78,154,590...78,173,032
Ensembl chr14:78,152,516...78,173,032
JBrowse link
G Paxip1 PAX interacting protein 1 decreases expression ISO methylselenic acid results in decreased expression of PAXIP1 mRNA CTD PMID:18548127 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Pbx1 PBX homeobox 1 increases expression ISO methylselenic acid results in increased expression of PBX1 mRNA CTD PMID:18548127 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 decreases expression ISO methylselenic acid results in decreased expression of PCBD1 mRNA CTD PMID:18548127 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292
JBrowse link
G Pcna proliferating cell nuclear antigen affects expression
decreases expression
ISO methylselenic acid affects the expression of PCNA mRNA
methylselenic acid results in decreased expression of PCNA mRNA
CTD PMID:11830524 PMID:12517777 PMID:14617803 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Peg3 paternally expressed 3 affects expression ISO methylselenic acid affects the expression of PEG3 mRNA CTD PMID:14617803 NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671
JBrowse link
G Pfdn5 prefoldin subunit 5 decreases expression ISO methylselenic acid results in decreased expression of PFDN5 mRNA CTD PMID:11830524 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression ISO methylselenic acid results in decreased expression of PGAP2 mRNA CTD PMID:18548127 NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114
JBrowse link
G Pgm5 phosphoglucomutase 5 increases expression ISO methylselenic acid results in increased expression of PGM5 mRNA CTD PMID:18548127 NCBI chr 1:222,325,638...222,513,423
Ensembl chr 1:222,325,643...222,513,437
JBrowse link
G Pgr progesterone receptor affects expression ISO methylselenic acid affects the expression of PGR mRNA CTD PMID:16928829 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 increases expression ISO methylselenic acid results in increased expression of PJA2 mRNA CTD PMID:18548127 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression ISO methylselenic acid results in increased expression of PLA2G4A mRNA CTD PMID:18548127 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plcb4 phospholipase C, beta 4 increases expression ISO methylselenic acid results in increased expression of PLCB4 mRNA CTD PMID:12517777 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
JBrowse link
G Plk1 polo-like kinase 1 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of PLK1 mRNA
methylselenic acid affects the expression of PLK1 mRNA
CTD PMID:11830524 PMID:14617803 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component increases expression ISO methylselenic acid results in increased expression of PMS2 mRNA CTD PMID:12517777 NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO methylselenic acid results in decreased expression of POLA1 mRNA CTD PMID:12517777 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Polr2h RNA polymerase II, I and III subunit H decreases expression ISO methylselenic acid results in decreased expression of POLR2H mRNA CTD PMID:18548127 NCBI chr11:80,192,017...80,197,468
Ensembl chr11:80,192,032...80,197,515
JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 affects expression ISO methylselenic acid affects the expression of PPFIA1 mRNA CTD PMID:14617803 NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277
JBrowse link
G Ppil2 peptidylprolyl isomerase like 2 decreases expression ISO methylselenic acid results in decreased expression of PPIL2 mRNA CTD PMID:18548127 NCBI chr11:83,897,719...83,920,970
Ensembl chr11:83,897,764...83,922,144
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B increases expression ISO methylselenic acid results in increased expression of PPM1B mRNA CTD PMID:12517777 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO methylselenic acid results in increased expression of PPP1R15A mRNA CTD PMID:28161410 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta increases expression ISO methylselenic acid results in increased expression of PRKAR2B mRNA CTD PMID:18548127 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
G Prkca protein kinase C, alpha increases expression ISO methylselenic acid results in increased expression of PRKCA mRNA CTD PMID:12517777 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO methylselenic acid results in increased expression of PRKCB mRNA CTD PMID:18548127 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prnp prion protein increases expression ISO methylselenic acid results in increased expression of PRNP mRNA CTD PMID:18548127 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO methylselenic acid results in increased expression of PTEN mRNA CTD PMID:12517777 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO methylselenic acid results in decreased expression of PTGES mRNA CTD PMID:11830524 PMID:21669866 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Qk quaking increases expression ISO methylselenic acid results in increased expression of QKI mRNA CTD PMID:18548127 NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression ISO methylselenic acid results in increased expression of RAB28 mRNA CTD PMID:12517777 NCBI chr14:69,245,846...69,322,968
Ensembl chr14:69,245,854...69,322,967
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression
affects expression
ISO methylselenic acid results in increased expression of RAB31 mRNA
methylselenic acid affects the expression of RAB31 mRNA
CTD PMID:12517777 PMID:14617803 PMID:18548127 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
JBrowse link
G Rabac1 Rab acceptor 1 decreases expression ISO methylselenic acid results in decreased expression of RABAC1 mRNA CTD PMID:12517777 NCBI chr 1:80,564,029...80,567,164
Ensembl chr 1:80,564,033...80,567,163
JBrowse link
G Rad9a RAD9 checkpoint clamp component A increases expression ISO methylselenic acid results in increased expression of RAD9A mRNA CTD PMID:12517777 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression ISO methylselenic acid results in increased expression of RAPGEF4 mRNA CTD PMID:12517777 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein]; methylselenic acid results in decreased phosphorylation of and results in increased expression of RB1 protein CTD PMID:17847021 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rdh11 retinol dehydrogenase 11 affects expression ISO methylselenic acid affects the expression of RDH11 mRNA CTD PMID:14617803 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Reep1 receptor accessory protein 1 increases expression ISO methylselenic acid results in increased expression of REEP1 mRNA CTD PMID:18548127 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO methylselenic acid results in decreased expression of RFC5 mRNA CTD PMID:11830524 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 increases expression ISO methylselenic acid results in increased expression of RGL1 mRNA CTD PMID:18548127 NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191
JBrowse link
G Rgs10 regulator of G-protein signaling 10 increases expression ISO methylselenic acid results in increased expression of RGS10 mRNA CTD PMID:12517777 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697
JBrowse link
G Rhob ras homolog family member B affects expression ISO methylselenic acid affects the expression of RHOB mRNA CTD PMID:14617803 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 increases expression ISO methylselenic acid results in increased expression of RIMS3 mRNA CTD PMID:18548127 NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression ISO methylselenic acid results in increased expression of RND3 mRNA CTD PMID:18548127 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rpa2 replication protein A2 decreases expression ISO methylselenic acid results in decreased expression of RPA2 mRNA CTD PMID:12517777 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Rpia ribose 5-phosphate isomerase A decreases expression ISO methylselenic acid results in decreased expression of RPIA mRNA CTD PMID:18548127 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
JBrowse link
G Rpl27a ribosomal protein L27a decreases expression ISO methylselenic acid results in decreased expression of RPL27A mRNA CTD PMID:18548127 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpsa ribosomal protein SA decreases expression ISO methylselenic acid results in decreased expression of RPSA mRNA CTD PMID:11172735 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 affects expression ISO methylselenic acid affects the expression of RRM1 mRNA CTD PMID:14617803 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 affects expression ISO methylselenic acid affects the expression of RRM2 mRNA CTD PMID:14617803 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rxylt1 ribitol xylosyltransferase 1 decreases expression ISO methylselenic acid results in decreased expression of RXYLT1 mRNA CTD PMID:18548127 NCBI chr 7:57,770,841...57,782,695
Ensembl chr 7:57,770,842...57,782,657
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO methylselenic acid results in increased expression of S100A4 mRNA CTD PMID:18548127 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G Samd4a sterile alpha motif domain containing 4A increases expression ISO methylselenic acid results in increased expression of SAMD4 mRNA CTD PMID:18548127 NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects expression ISO methylselenic acid affects the expression of SAT1 mRNA CTD PMID:14617803 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Scd stearoyl-CoA desaturase affects expression ISO methylselenic acid affects the expression of SCD mRNA CTD PMID:14617803 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sdc2 syndecan 2 increases expression ISO methylselenic acid results in increased expression of SDC2 mRNA CTD PMID:18548127 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component affects expression ISO methylselenic acid affects the expression of SEC24D mRNA CTD PMID:14617803 NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587
JBrowse link
G Sema5a semaphorin 5A increases expression ISO methylselenic acid results in increased expression of SEMA5A mRNA CTD PMID:18548127 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
JBrowse link
G Serpinb5 serpin family B member 5 increases expression
affects expression
ISO methylselenic acid results in increased expression of SERPINB5 mRNA
methylselenic acid affects the expression of SERPINB5 mRNA
CTD PMID:14617803 PMID:18548127 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpinb6a serpin family B member 6A decreases expression ISO methylselenic acid results in decreased expression of SERPINB6 mRNA CTD PMID:18548127 NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO methylselenic acid results in increased expression of SERPINE2 mRNA CTD PMID:18548127 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpinf1 serpin family F member 1 increases expression ISO methylselenic acid results in increased expression of SERPINF1 mRNA CTD PMID:18548127 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 affects expression ISO methylselenic acid affects the expression of SGK1 mRNA CTD PMID:14617803 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sh3bgr SH3 domain binding glutamate-rich protein increases expression ISO methylselenic acid results in increased expression of SH3BGR mRNA CTD PMID:18548127 NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 affects expression ISO methylselenic acid affects the expression of SH3BP5 mRNA CTD PMID:14617803 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) increases expression ISO methylselenic acid results in increased expression of SLC14A1 mRNA CTD PMID:18548127 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
JBrowse link
G Slc16a7 solute carrier family 16 member 7 increases expression ISO methylselenic acid results in increased expression of SLC16A7 mRNA CTD PMID:18548127 NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
JBrowse link
G Slc19a1 solute carrier family 19 member 1 decreases expression ISO methylselenic acid results in decreased expression of SLC19A1 mRNA CTD PMID:18548127 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Smad7 SMAD family member 7 increases expression ISO methylselenic acid results in increased expression of SMAD7 mRNA CTD PMID:18548127 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 decreases expression ISO methylselenic acid results in decreased expression of SMARCA4 mRNA CTD PMID:18548127 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 increases expression ISO methylselenic acid results in increased expression of SMARCD3 mRNA CTD PMID:18548127 NCBI chr 4:10,548,693...10,580,334
Ensembl chr 4:10,548,751...10,580,326
JBrowse link
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 decreases expression ISO methylselenic acid results in decreased expression of SMARCE1 mRNA CTD PMID:12517777 NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO methylselenic acid results in increased expression of SNAI2 mRNA CTD PMID:18548127 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Snap25 synaptosome associated protein 25 increases expression ISO methylselenic acid results in increased expression of SNAP25 mRNA CTD PMID:18548127 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Sncg synuclein, gamma increases expression ISO methylselenic acid results in increased expression of SNCG mRNA CTD PMID:18548127 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 decreases expression ISO methylselenic acid results in decreased expression of SND1 mRNA CTD PMID:18548127 NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
JBrowse link
G Snx1 sorting nexin 1 increases expression ISO methylselenic acid results in increased expression of SNX1 mRNA CTD PMID:18548127 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 increases expression ISO methylselenic acid results in increased expression of SORBS1 mRNA CTD PMID:18548127 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO methylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter] CTD PMID:17876054 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor increases expression ISO methylselenic acid results in increased expression of SPDEF protein CTD PMID:18567002 NCBI chr20:5,771,434...5,786,793
Ensembl chr20:5,771,441...5,785,893
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression ISO methylselenic acid results in increased expression of SPTAN1 mRNA CTD PMID:18548127 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Srp19 signal recognition particle 19 decreases expression ISO methylselenic acid results in decreased expression of SRP19 mRNA CTD PMID:18548127 NCBI chr18:25,931,734...25,937,974
Ensembl chr18:25,931,589...25,938,017
JBrowse link
G Ssbp2 single-stranded DNA binding protein 2 increases expression ISO methylselenic acid results in increased expression of SSBP2 mRNA CTD PMID:18548127 NCBI chr 2:22,650,488...22,933,696
Ensembl chr 2:22,651,258...22,933,696
JBrowse link
G ST7 suppression of tumorigenicity 7 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of ST7 mRNA
methylselenic acid affects the expression of ST7 mRNA
CTD PMID:14617803 PMID:18548127 NCBI chr 4:46,041,655...46,289,745
Ensembl chr 4:46,042,236...46,289,740
JBrowse link
G Stom stomatin increases expression ISO methylselenic acid results in increased expression of STOM mRNA CTD PMID:18548127 NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354
JBrowse link
G Stx12 syntaxin 12 increases expression ISO methylselenic acid results in increased expression of STX12 mRNA CTD PMID:18548127 NCBI chr 5:145,062,978...145,092,423
Ensembl chr 5:145,063,587...145,092,377
JBrowse link
G Stx1a syntaxin 1A affects expression ISO methylselenic acid affects the expression of STX1A mRNA CTD PMID:14617803 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Stx2 syntaxin 2 increases expression ISO methylselenic acid results in increased expression of STX2 mRNA CTD PMID:18548127 NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751
JBrowse link
G Svil supervillin increases expression ISO methylselenic acid results in increased expression of SVIL mRNA CTD PMID:18548127 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 decreases expression ISO methylselenic acid results in decreased expression of TACSTD2 mRNA CTD PMID:18548127 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex decreases expression ISO methylselenic acid results in decreased expression of TARBP2 mRNA CTD PMID:18548127 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked increases expression ISO methylselenic acid results in increased expression of TBL1X mRNA CTD PMID:18548127 NCBI chr  X:41,574,558...41,731,117
Ensembl chr  X:41,576,047...41,731,101
JBrowse link
G Tbxas1 thromboxane A synthase 1 decreases expression ISO methylselenic acid results in decreased expression of TBXAS1 mRNA CTD PMID:21669866 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
G Tcn2 transcobalamin 2 increases expression ISO methylselenic acid results in increased expression of TCN2 mRNA CTD PMID:18548127 NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO methylselenic acid inhibits the reaction [afimoxifene results in increased expression of TFF1 mRNA]; methylselenic acid inhibits the reaction [Estradiol results in increased expression of TFF1 mRNA] CTD PMID:16093440 PMID:16155795 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO methylselenic acid results in increased expression of TGFB1 mRNA CTD PMID:12517777 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO methylselenic acid results in increased expression of TGFB2 mRNA CTD PMID:18548127 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO methylselenic acid results in increased expression of TGFBR2 mRNA CTD PMID:18548127 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 increases expression ISO methylselenic acid results in increased expression of TGFBR3 mRNA CTD PMID:12517777 PMID:18548127 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Tle2 TLE family member 2, transcriptional corepressor increases expression ISO methylselenic acid results in increased expression of TLE2 mRNA CTD PMID:18548127 NCBI chr 7:8,119,049...8,135,385
Ensembl chr 7:8,119,053...8,134,306
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO methylselenic acid results in increased expression of TLR2 mRNA CTD PMID:12517777 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tmprss2 transmembrane serine protease 2 affects expression ISO methylselenic acid affects the expression of TMPRSS2 mRNA CTD PMID:14617803 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 affects expression ISO methylselenic acid affects the expression of TNFAIP3 mRNA CTD PMID:14617803 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO methylselenic acid results in increased expression of TNFRSF25 mRNA CTD PMID:11830524 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Top2a DNA topoisomerase II alpha affects expression ISO methylselenic acid affects the expression of TOP2A mRNA CTD PMID:14617803 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tor1aip1 torsin 1A interacting protein 1 increases expression ISO methylselenic acid results in increased expression of TOR1AIP1 mRNA CTD PMID:18548127 NCBI chr13:68,196,681...68,226,121
Ensembl chr13:68,196,681...68,225,862
JBrowse link
G Tpm1 tropomyosin 1 increases expression ISO methylselenic acid results in increased expression of TPM1 mRNA CTD PMID:18548127 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Trib1 tribbles pseudokinase 1 decreases expression ISO methylselenic acid results in decreased expression of TRIB1 mRNA CTD PMID:18548127 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
G Trim14 tripartite motif-containing 14 decreases expression ISO methylselenic acid results in decreased expression of TRIM14 mRNA CTD PMID:18548127 NCBI chr 5:60,800,032...60,825,481
Ensembl chr 5:60,800,032...60,824,858
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO methylselenic acid results in decreased expression of TTK mRNA CTD PMID:18548127 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases metabolic processing ISO TXNRD1 protein results in increased metabolism of methylselenic acid CTD PMID:11782468 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Tyms thymidylate synthetase decreases expression
affects expression
ISO methylselenic acid results in decreased expression of TYMS mRNA
methylselenic acid affects the expression of TYMS mRNA
CTD PMID:12517777 PMID:14617803 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Uck2 uridine-cytidine kinase 2 decreases expression ISO methylselenic acid results in decreased expression of UCK2 mRNA CTD PMID:18548127 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO methylselenic acid affects the expression of UGDH mRNA CTD PMID:14617803 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Utrn utrophin decreases expression ISO methylselenic acid results in decreased expression of UTRN mRNA CTD PMID:18548127 NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 increases expression ISO methylselenic acid results in increased expression of VAMP3 mRNA CTD PMID:18548127 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751
JBrowse link
G Vdr vitamin D receptor affects expression ISO methylselenic acid affects the expression of VDR mRNA CTD PMID:16928829 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression ISO methylselenic acid results in decreased expression of VEGFC mRNA CTD PMID:12517777 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vim vimentin increases expression ISO methylselenic acid results in increased expression of VIM mRNA CTD PMID:18548127 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wasf1 WASP family member 1 affects expression ISO methylselenic acid affects the expression of WASF1 mRNA CTD PMID:14617803 NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996
JBrowse link
G Wnt7a Wnt family member 7A decreases expression ISO methylselenic acid results in decreased expression of WNT7A mRNA CTD PMID:12517777 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981
JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 decreases expression ISO methylselenic acid results in decreased expression of WSB2 mRNA CTD PMID:18548127 NCBI chr12:39,217,645...39,238,667
Ensembl chr12:39,217,648...39,238,640
JBrowse link
G Xbp1 X-box binding protein 1 increases splicing ISO methylselenic acid results in increased splicing of XBP1 mRNA CTD PMID:16205645 PMID:28161410 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon decreases expression ISO methylselenic acid results in decreased expression of YWHAE mRNA CTD PMID:18548127 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Zcchc24 zinc finger CCHC-type containing 24 increases expression ISO methylselenic acid results in increased expression of ZCCHC24 mRNA CTD PMID:18548127 NCBI chr16:1,274,544...1,326,664
Ensembl chr16:1,274,548...1,326,696
JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO methylselenic acid results in increased expression of ZNF274 mRNA CTD PMID:12517777 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
JBrowse link
G Zfp217 zinc finger protein 217 increases expression ISO methylselenic acid results in increased expression of ZNF217 mRNA CTD PMID:12517777 NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040
JBrowse link
G Zfp24 zinc finger protein 24 decreases expression ISO methylselenic acid results in decreased expression of ZNF24 mRNA CTD PMID:18548127 NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,298,290...15,306,799
JBrowse link
G Zfp267 zinc finger protein 267 increases expression ISO methylselenic acid results in increased expression of ZNF267 mRNA CTD PMID:12517777 NCBI chr 2:119,017,244...119,035,885
Ensembl chr 2:119,017,285...119,031,900
JBrowse link
G Zfp458 zinc finger protein 458 decreases expression ISO methylselenic acid results in decreased expression of ZNF43 mRNA CTD PMID:18548127 NCBI chr 2:84,661,150...84,705,631
Ensembl chr 2:84,693,186...84,702,558
JBrowse link
Se-methyl-L-selenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
decreases expression
EXP Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Ar androgen receptor decreases expression ISO
EXP
selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA
CTD PMID:16637076 PMID:19025659 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP selenomethylselenocysteine results in decreased expression of ARNTL mRNA CTD PMID:19122877 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Banp Btg3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of BCL2 mRNA
selenomethylselenocysteine results in decreased expression of BCL2 protein
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
CTD PMID:11396176 PMID:19360359 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bmf Bcl2 modifying factor multiple interactions
increases expression
ISO 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF protein
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein
CTD PMID:25321483 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO selenomethylselenocysteine results in increased activity of CASP3 protein
selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]
CTD PMID:15318939 PMID:25321483 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]
CTD PMID:25321483 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein
CTD PMID:11396176 PMID:18855134 PMID:19276161 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein
CTD PMID:25321483 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176 PMID:19276161 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression EXP selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1 CTD PMID:15897249 NCBI chr14:78,103,876...78,119,976
Ensembl chr14:78,103,876...78,119,953
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of ESR1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein
CTD PMID:18855134 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Faslg Fas ligand multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG CTD PMID:15897249 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO selenomethylselenocysteine results in increased expression of GADD45A mRNA CTD PMID:10656618 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity
increases expression
ISO selenomethylselenocysteine results in increased activity of GPX1 protein
selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein
CTD PMID:18514395 PMID:19033020 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO selenomethylselenocysteine results in increased expression of GPX4 mRNA CTD PMID:18514395 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK1 mRNA CTD PMID:18514395 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK3 mRNA CTD PMID:18514395 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP selenomethylselenocysteine results in increased phosphorylation of JUN protein CTD PMID:19276161 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of KLK3 protein CTD PMID:16637076 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
decreases expression
ISO [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein
selenomethylselenocysteine results in decreased expression of MKI67 protein
CTD PMID:18855134 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO selenomethylselenocysteine results in increased expression of MSRB1 mRNA CTD PMID:18514395 NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21213327 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21213327 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO selenomethylselenocysteine results in increased expression of P4HA1 mRNA CTD PMID:18514395 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form] CTD PMID:25321483 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Per2 period circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of PER2 mRNA CTD PMID:19122877 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Per3 period circadian regulator 3 increases expression EXP selenomethylselenocysteine results in increased expression of PER3 mRNA CTD PMID:19122877 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pgr progesterone receptor decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of PGR protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein
CTD PMID:18855134 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO selenomethylselenocysteine results in increased expression of PPP1R15A mRNA CTD PMID:10656618 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCE protein CTD PMID:10656618 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcz protein kinase C, zeta decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCZ protein CTD PMID:10656618 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB3B mRNA CTD PMID:18514395 NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB4A mRNA CTD PMID:18514395 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:21213327 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO selenomethylselenocysteine results in increased expression of SCARB1 mRNA CTD PMID:18514395 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Selenof selenoprotein F increases expression ISO selenomethylselenocysteine results in increased expression of SELENOF mRNA CTD PMID:18514395 NCBI chr 2:233,642,075...233,674,853
Ensembl chr 2:233,641,932...233,674,846
JBrowse link
G Selenop selenoprotein P increases expression ISO selenomethylselenocysteine results in increased expression of SELENOP mRNA CTD PMID:18514395 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Selenow selenoprotein W increases expression ISO selenomethylselenocysteine results in increased expression of SELENOW mRNA CTD PMID:18514395 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907
JBrowse link
G Slc6a19 solute carrier family 6 member 19 increases uptake ISO SLC6A19 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 1:29,586,205...29,604,960
Ensembl chr 1:29,586,195...29,604,962
JBrowse link
G Snap23 synaptosome associated protein 23 decreases expression ISO selenomethylselenocysteine results in decreased expression of SNAP23 mRNA CTD PMID:18514395 NCBI chr 3:107,514,088...107,546,177 JBrowse link
G Sort1 sortilin 1 increases expression ISO selenomethylselenocysteine results in increased expression of SORT1 mRNA CTD PMID:18514395 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions EXP [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein CTD PMID:19025659 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein CTD PMID:19360359 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 increases expression ISO selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA CTD PMID:18514395 NCBI chr 5:144,507,044...144,524,142
Ensembl chr 5:144,507,615...144,524,131
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:60,431,673...60,476,438
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
Se-methylselenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
decreases expression
EXP Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Ar androgen receptor decreases expression ISO
EXP
selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA
CTD PMID:16637076 PMID:19025659 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP selenomethylselenocysteine results in decreased expression of ARNTL mRNA CTD PMID:19122877 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Banp Btg3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of BCL2 mRNA
selenomethylselenocysteine results in decreased expression of BCL2 protein
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
CTD PMID:11396176 PMID:19360359 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bmf Bcl2 modifying factor multiple interactions
increases expression
ISO 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF protein
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein
CTD PMID:25321483 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO selenomethylselenocysteine results in increased activity of CASP3 protein
selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]
CTD PMID:15318939 PMID:25321483 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]
CTD PMID:25321483 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein
CTD PMID:11396176 PMID:18855134 PMID:19276161 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein
CTD PMID:25321483 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176 PMID:19276161 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression EXP selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1 CTD PMID:15897249 NCBI chr14:78,103,876...78,119,976
Ensembl chr14:78,103,876...78,119,953
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of ESR1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein
CTD PMID:18855134 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Faslg Fas ligand multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG CTD PMID:15897249 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO selenomethylselenocysteine results in increased expression of GADD45A mRNA CTD PMID:10656618 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity
increases expression
ISO selenomethylselenocysteine results in increased activity of GPX1 protein
selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein
CTD PMID:18514395 PMID:19033020 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO selenomethylselenocysteine results in increased expression of GPX4 mRNA CTD PMID:18514395 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK1 mRNA CTD PMID:18514395 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK3 mRNA CTD PMID:18514395 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP selenomethylselenocysteine results in increased phosphorylation of JUN protein CTD PMID:19276161 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of KLK3 protein CTD PMID:16637076 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
decreases expression
ISO [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein
selenomethylselenocysteine results in decreased expression of MKI67 protein
CTD PMID:18855134 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO selenomethylselenocysteine results in increased expression of MSRB1 mRNA CTD PMID:18514395 NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21213327 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21213327 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO selenomethylselenocysteine results in increased expression of P4HA1 mRNA CTD PMID:18514395 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form] CTD PMID:25321483 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Per2 period circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of PER2 mRNA CTD PMID:19122877 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Per3 period circadian regulator 3 increases expression EXP selenomethylselenocysteine results in increased expression of PER3 mRNA CTD PMID:19122877 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pgr progesterone receptor decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of PGR protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein
CTD PMID:18855134 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO selenomethylselenocysteine results in increased expression of PPP1R15A mRNA CTD PMID:10656618 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCE protein CTD PMID:10656618 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcz protein kinase C, zeta decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCZ protein CTD PMID:10656618 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB3B mRNA CTD PMID:18514395 NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB4A mRNA CTD PMID:18514395 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:21213327 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO selenomethylselenocysteine results in increased expression of SCARB1 mRNA CTD PMID:18514395 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Selenof selenoprotein F increases expression ISO selenomethylselenocysteine results in increased expression of SELENOF mRNA CTD PMID:18514395 NCBI chr 2:233,642,075...233,674,853
Ensembl chr 2:233,641,932...233,674,846
JBrowse link
G Selenop selenoprotein P increases expression ISO selenomethylselenocysteine results in increased expression of SELENOP mRNA CTD PMID:18514395 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Selenow selenoprotein W increases expression ISO selenomethylselenocysteine results in increased expression of SELENOW mRNA CTD PMID:18514395 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907
JBrowse link
G Slc6a19 solute carrier family 6 member 19 increases uptake ISO SLC6A19 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 1:29,586,205...29,604,960
Ensembl chr 1:29,586,195...29,604,962
JBrowse link
G Snap23 synaptosome associated protein 23 decreases expression ISO selenomethylselenocysteine results in decreased expression of SNAP23 mRNA CTD PMID:18514395 NCBI chr 3:107,514,088...107,546,177 JBrowse link
G Sort1 sortilin 1 increases expression ISO selenomethylselenocysteine results in increased expression of SORT1 mRNA CTD PMID:18514395 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions EXP [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein CTD PMID:19025659 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein CTD PMID:19360359 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 increases expression ISO selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA CTD PMID:18514395 NCBI chr 5:144,507,044...144,524,142
Ensembl chr 5:144,507,615...144,524,131
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:60,431,673...60,476,438
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
selenocystine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of GCLC mRNA] CTD PMID:22807314 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO selenocystine inhibits the reaction [Methylmercury Compounds results in decreased activity of MAPK1 protein] CTD PMID:23838314 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO selenocystine inhibits the reaction [Methylmercury Compounds results in decreased activity of MAPK3 protein] CTD PMID:23838314 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects localization
ISO NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of TXNRD1 mRNA]
selenocystine affects the localization of NFE2L2 protein
CTD PMID:22807314 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
affects expression
ISO NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of NQO1 mRNA]
selenocystine results in increased expression of NQO1 protein
selenocystine affects the expression of NQO1 mRNA
CTD PMID:22807314 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenocystine CTD PMID:18845132 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases response to substance
increases expression
multiple interactions
ISO TXNRD1 protein results in decreased susceptibility to selenocystine
selenocystine results in increased expression of TXNRD1 mRNA; selenocystine results in increased expression of TXNRD1 protein
NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of TXNRD1 mRNA]
CTD PMID:20920480 PMID:22807314 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions
decreases activity
ISO<