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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organoselenium compound
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Accession:CHEBI:25712 term browser browse the term
Definition:An organoselenium compound is a compound containing at least one carbon-selenium bond.
Synonyms:related_synonym: organoselenium compounds
 alt_id: MESH:D016566
 xref_mesh: MESH:D016566


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organoselenium compound term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA CTD PMID:25167922 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein]
[Organoselenium Compounds binds to Copper] which results in decreased expression of AKT1 protein
CTD PMID:18538761, PMID:25167922 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein] CTD PMID:25301743 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] CTD PMID:25301743 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases cleavage ISO Organoselenium Compounds results in increased cleavage of CASP3 protein CTD PMID:24905917 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein] CTD PMID:25301743 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Organoselenium Compounds binds to and results in decreased activity of CYP1A1 protein CTD PMID:21732699 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Organoselenium Compounds binds to and results in decreased activity of CYP1A2 protein CTD PMID:21732699 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Organoselenium Compounds binds to and results in decreased activity of CYP1B1 protein CTD PMID:21732699 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJA1 mRNA CTD PMID:25167922 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJA4 mRNA CTD PMID:25167922 NCBI chr 8:59,278,262...59,294,003
Ensembl chr 8:59,278,262...59,294,003
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB1 mRNA CTD PMID:25167922 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB4 mRNA CTD PMID:25167922 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB6 mRNA CTD PMID:25167922 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of DNAJB9 mRNA CTD PMID:25167922 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of EGLN3 mRNA CTD PMID:25167922 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO Organoselenium Compounds results in increased activity of EPHX1 protein CTD PMID:17163488 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein] CTD PMID:25301743 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of FOS mRNA CTD PMID:25167922 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of FOSL1 mRNA CTD PMID:25167922 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of GCLM mRNA CTD PMID:25167922 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO [Organoselenium Compounds co-treated with Lipopolysaccharides] results in increased expression of GPX1 protein
Organoselenium Compounds results in increased expression of GPX1 protein
CTD PMID:20883674 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HERPUD1 mRNA CTD PMID:25167922 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HMOX1 mRNA CTD PMID:25167922 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of HSP90AA1 protein; [Organoselenium Compounds binds to Copper] which results in increased expression of HSP90AA1 mRNA CTD PMID:25167922 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1A mRNA CTD PMID:25167922 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1B mRNA CTD PMID:25167922 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1L mRNA CTD PMID:25167922 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPB8 mRNA CTD PMID:25167922 NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of HSPH1 mRNA CTD PMID:25167922 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ifng interferon gamma multiple interactions ISO Organoselenium Compounds inhibits the reaction [Freund's Adjuvant results in increased expression of IFNG mRNA] CTD PMID:31400342 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:18538761 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of JUN mRNA CTD PMID:25167922 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of JUNB mRNA CTD PMID:25167922 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MAFF mRNA CTD PMID:25167922 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mafg MAF bZIP transcription factor G multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MAFG mRNA CTD PMID:25167922 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of MAP2K6 mRNA CTD PMID:25167922 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
increases activity
EXP Organoselenium Compounds analog results in increased phosphorylation of MAPK1 protein
Organoselenium Compounds results in increased activity of MAPK1 protein
CTD PMID:21960664, PMID:22001386 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MAPK15 mRNA CTD PMID:25167922 NCBI chr 7:117,041,287...117,061,799
Ensembl chr 7:117,055,395...117,061,047
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
increases phosphorylation
EXP Organoselenium Compounds results in increased activity of MAPK3 protein
Organoselenium Compounds analog results in increased phosphorylation of MAPK3 protein
CTD PMID:21960664, PMID:22001386 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA CTD PMID:25167922 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp10 matrix metallopeptidase 10 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MMP10 mRNA CTD PMID:25167922 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp25 matrix metallopeptidase 25 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MMP25 mRNA CTD PMID:25167922 NCBI chr10:12,962,214...12,966,377 JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of MT2A mRNA CTD PMID:25167922 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of NOS2 protein]
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
CTD PMID:18538761, PMID:20883674 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Organoselenium Compounds results in increased cleavage of PARP1 protein CTD PMID:24905917 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgf placental growth factor multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of PGF mRNA CTD PMID:25167922 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of PIK3R5 mRNA CTD PMID:25167922 NCBI chr10:55,013,686...55,078,986
Ensembl chr10:55,013,703...55,080,421
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of PIM1 protein; [Organoselenium Compounds binds to Copper] which results in increased expression of PIM1 mRNA CTD PMID:25167922 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of PPP1R15A mRNA CTD PMID:25167922 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
ISO
EXP
Organoselenium Compounds inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of PTGS2 protein]
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Organoselenium Compounds results in decreased activity of PTGS2 protein
CTD PMID:18538761, PMID:20883674, PMID:31400342 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein] CTD PMID:18538761 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SGK1 mRNA CTD PMID:25167922 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein] CTD PMID:25301743 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SLC2A1 mRNA CTD PMID:25167922 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SLC2A3 mRNA CTD PMID:25167922 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of SQSTM1 mRNA CTD PMID:25167922 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Organoselenium Compounds results in decreased susceptibility to [Lipopolysaccharides results in increased expression of TNF mRNA]
Organoselenium Compounds results in decreased expression of TNF protein
Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:18538761, PMID:20883674, PMID:31400342 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of TRIB3 mRNA CTD PMID:25167922 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of TXNRD1 mRNA CTD PMID:25167922 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in increased expression of VEGFA mRNA CTD PMID:25167922 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO [Organoselenium Compounds binds to Copper] which results in decreased expression of VEGFC mRNA CTD PMID:25167922 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
ebselen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16757516 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO ebselen inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA] CTD PMID:11133813 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
EXP
ISO
Dithiothreitol inhibits the reaction [ebselen results in decreased activity of ALAD protein]
ebselen inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]
CTD PMID:14630126, PMID:17624921, PMID:23933410 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity ISO ebselen results in decreased activity of ALOX5 protein CTD PMID:7590103 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of BAX protein] CTD PMID:30558456 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein] CTD PMID:30558456 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein]
ebselen results in increased activity of CASP3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; ebselen inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
CTD PMID:21300091, PMID:23649643, PMID:25068500, PMID:30558456 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein]
ebselen inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]
CTD PMID:18629305, PMID:23649643 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP ebselen results in increased activity of CAT protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:27282967, PMID:30558456 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO ebselen results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cs citrate synthase multiple interactions ISO ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:11903743 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP ebselen results in increased phosphorylation of EIF2S1 protein CTD PMID:27282967 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO ebselen binds to and results in decreased activity of EPHX2 protein CTD PMID:23219563 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of FOS protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of FOS protein] CTD PMID:14572605 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gck glucokinase multiple interactions ISO [ebselen co-treated with Glucose] results in increased activity of GCK protein CTD PMID:23795780 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gfap glial fibrillary acidic protein increases phosphorylation EXP ebselen results in increased phosphorylation of GFAP protein CTD PMID:27282967 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]; ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 protein] CTD PMID:12958040 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
ebselen inhibits the reaction [Methylmercury Compounds results in decreased activity of GPX1 protein]
CTD PMID:23795780, PMID:28383113 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
EXP ebselen results in increased activity of GSR protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD PMID:27282967, PMID:30558456 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein] CTD PMID:8147899 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]; ebselen binds to and results in decreased activity of GSTA3 protein CTD PMID:8147899 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP ebselen binds to and results in decreased activity of GSTP1 protein CTD PMID:8147899 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]] CTD PMID:19374849 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [ebselen affects the abundance of Reactive Oxygen Species] which results in decreased expression of HMOX1 protein; [ebselen affects the abundance of Reactive Oxygen Species] which results in increased activity of HMOX1 protein CTD PMID:16959961 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO ebselen results in increased expression of HPGDS mRNA CTD PMID:21669866 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Ifng interferon gamma multiple interactions ISO ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:12794164 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il6 interleukin 6 multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of IL6 protein] CTD PMID:30558456 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen results in increased activity of MAPK1 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen analog results in increased phosphorylation of MAPK1 protein; ebselen results in increased phosphorylation of MAPK1 protein
CTD PMID:20495008, PMID:21300091, PMID:21960664, PMID:22001386, PMID:27282967 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
ebselen results in increased activity of MAPK3 protein
ebselen analog results in increased phosphorylation of MAPK3 protein; ebselen results in increased phosphorylation of MAPK3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:20495008, PMID:21300091, PMID:21960664, PMID:22001386, PMID:27282967 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation EXP ebselen results in increased phosphorylation of MAPK9 protein CTD PMID:27282967 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP13 mRNA] CTD PMID:11903743 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Ngf nerve growth factor multiple interactions ISO ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO
EXP
ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]
ebselen results in decreased activity of NOS2 protein
CTD PMID:7590103, PMID:12794164 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity EXP ebselen results in decreased activity of NQO1 protein CTD PMID:7590103 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO [ebselen co-treated with Glucose] results in increased expression of PDX1 protein CTD PMID:23795780 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 decreases activity ISO ebselen results in decreased activity of PHOSPHO1 protein CTD PMID:17227223 NCBI chr10:83,635,557...83,643,862
Ensembl chr10:83,636,518...83,643,859
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of RELA protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of RELA protein] CTD PMID:14572605 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:16984886 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO [ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein CTD PMID:23795780 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:21131394 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod1 superoxide dismutase 1 decreases response to substance
multiple interactions
ISO ebselen results in decreased susceptibility to SOD1 protein mutant form
ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:16702190, PMID:23795780 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]
ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD PMID:11903743, PMID:16757516, PMID:21131394 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:11903743 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of TNF protein] CTD PMID:30558456 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO ebselen results in increased expression of and results in increased activity of TXNRD1 protein CTD PMID:28383113 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [ebselen co-treated with Glucose] results in decreased expression of UCP2 protein CTD PMID:23795780 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Xbp1 X-box binding protein 1 increases phosphorylation EXP ebselen results in increased phosphorylation of XBP1 protein CTD PMID:27282967 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO ebselen inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
methylseleninic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
affects expression
decreases expression
ISO AR protein inhibits the reaction [methylselenic acid results in decreased expression of ABCC4 mRNA]
methylselenic acid affects the expression of ABCC4 mRNA
CTD PMID:14617803, PMID:16020662, PMID:18548127 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Acp3 acid phosphatase 3 affects expression ISO methylselenic acid affects the expression of ACP3 mRNA CTD PMID:14617803 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 affects expression
decreases expression
ISO methylselenic acid affects the expression of ACSL3 mRNA
methylselenic acid results in decreased expression of ACSL3 mRNA
CTD PMID:14617803, PMID:18548127 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO methylselenic acid results in increased expression of ACTA2 mRNA CTD PMID:18548127 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression ISO methylselenic acid results in increased expression of ACTG2 mRNA CTD PMID:18548127 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO methylselenic acid results in increased expression of ADAM22 mRNA CTD PMID:18548127 NCBI chr 4:22,864,485...23,002,969
Ensembl chr 4:22,859,622...22,996,645
JBrowse link
G Add3 adducin 3 increases expression ISO methylselenic acid results in increased expression of ADD3 mRNA CTD PMID:12517777 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 increases expression ISO methylselenic acid results in increased expression of ADGRL3 mRNA CTD PMID:18548127 NCBI chr14:28,362,176...29,226,085
Ensembl chr14:28,393,394...28,967,980
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO methylselenic acid results in increased expression of AHR mRNA CTD PMID:18548127 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO methylselenic acid results in increased expression of AKAP12 mRNA CTD PMID:18548127 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akap2 A-kinase anchoring protein 2 increases expression ISO methylselenic acid results in increased expression of PALM2AKAP2 mRNA CTD PMID:18548127 NCBI chr 5:74,874,245...74,985,789
Ensembl chr 5:74,874,306...74,982,401
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO methylselenic acid results in increased expression of AKR1B1 mRNA CTD PMID:18548127 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases response to substance
decreases phosphorylation
ISO [methylselenic acid results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]
AKT1 protein results in decreased susceptibility to methylselenic acid
CTD PMID:15845651, PMID:17339365 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO methylselenic acid results in decreased expression of AKT2 mRNA CTD PMID:11830524 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alad aminolevulinate dehydratase increases expression ISO methylselenic acid results in increased expression of ALAD mRNA CTD PMID:18548127 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase decreases expression ISO methylselenic acid results in decreased expression of ALG3 mRNA CTD PMID:18548127 NCBI chr11:83,985,484...83,991,706
Ensembl chr11:83,986,230...83,991,706
JBrowse link
G Alg8 ALG8, alpha-1,3-glucosyltransferase decreases expression ISO methylselenic acid results in decreased expression of ALG8 mRNA CTD PMID:18548127 NCBI chr 1:162,342,061...162,362,139
Ensembl chr 1:162,342,051...162,362,141
JBrowse link
G Amt aminomethyltransferase increases expression ISO methylselenic acid results in increased expression of AMT mRNA CTD PMID:18548127 NCBI chr 8:117,068,388...117,078,633
Ensembl chr 8:117,068,582...117,077,913
JBrowse link
G Ank2 ankyrin 2 increases expression ISO methylselenic acid results in increased expression of ANK2 mRNA CTD PMID:18548127 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ank3 ankyrin 3 decreases expression ISO methylselenic acid results in decreased expression of ANK3 mRNA CTD PMID:18548127 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Apod apolipoprotein D affects expression ISO methylselenic acid affects the expression of APOD mRNA CTD PMID:14617803 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Ar androgen receptor affects response to substance
increases degradation
decreases expression
decreases activity
multiple interactions
ISO AR protein affects the susceptibility to methylselenic acid
methylselenic acid results in increased degradation of AR mRNA; methylselenic acid results in increased degradation of AR protein
methylselenic acid results in decreased expression of AR mRNA; methylselenic acid results in decreased expression of AR protein
methylselenic acid results in decreased activity of AR protein
AR protein inhibits the reaction [methylselenic acid results in decreased expression of ABCC4 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A1 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of KLK2 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of KLK3 mRNA]; methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 promoter]]; Superoxides promotes the reaction [methylselenic acid results in decreased expression of AR protein]
CTD PMID:14617803, PMID:15141018, PMID:16020662, PMID:16648561, PMID:16928829 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO methylselenic acid results in increased expression of ARHGEF2 mRNA CTD PMID:18548127 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression ISO methylselenic acid results in increased expression of ARL4A mRNA CTD PMID:18548127 NCBI chr 6:59,945,926...59,950,586
Ensembl chr 6:59,948,577...59,950,586
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO methylselenic acid results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:11830524 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf3 activating transcription factor 3 affects expression ISO methylselenic acid affects the expression of ATF3 mRNA CTD PMID:14617803 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO methylselenic acid results in decreased expression of ATF5 mRNA CTD PMID:12517777, PMID:18548127 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO methylselenic acid results in increased cleavage of and results in increased activity of ATF6 protein CTD PMID:16205645 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO methylselenic acid results in increased expression of ATP2A2 mRNA CTD PMID:18548127 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO methylselenic acid results in increased expression of ATP2B4 mRNA CTD PMID:18548127 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Aurka aurora kinase A affects expression
decreases expression
ISO methylselenic acid affects the expression of AURKA mRNA
methylselenic acid results in decreased expression of AURKA mRNA
CTD PMID:12517777, PMID:14617803 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 affects expression ISO methylselenic acid affects the expression of B4GALT1 mRNA CTD PMID:14617803 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO methylselenic acid results in increased expression of BACH1 mRNA CTD PMID:12517777 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression EXP methylselenic acid affects the expression of BAX protein CTD PMID:12017302 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO methylselenic acid results in increased expression of BBC3 mRNA CTD PMID:28161410 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression EXP methylselenic acid affects the expression of BCL2 protein CTD PMID:12017302 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO methylselenic acid results in increased expression of BCL2A1 mRNA CTD PMID:11830524 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions
increases cleavage
increases expression
ISO BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; Tamoxifen promotes the reaction [methylselenic acid results in increased cleavage of BCL2L11 protein]
methylselenic acid results in increased expression of BCL2L11 mRNA; methylselenic acid results in increased expression of BCL2L11 protein
CTD PMID:17339365, PMID:18790785, PMID:28161410 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects expression ISO methylselenic acid affects the expression of BIRC2 mRNA CTD PMID:14617803 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects expression ISO methylselenic acid affects the expression of BIRC3 mRNA CTD PMID:14617803 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of BIRC5 protein; methylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter]
methylselenic acid results in decreased expression of BIRC5 mRNA; methylselenic acid results in decreased expression of BIRC5 protein
CTD PMID:12517777, PMID:17876054, PMID:18444175, PMID:18567002 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO methylselenic acid results in increased expression of BMP4 mRNA CTD PMID:12517777 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO methylselenic acid results in increased expression of BRCA2 mRNA CTD PMID:12517777 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO methylselenic acid results in increased expression of BTG3 mRNA CTD PMID:18548127 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B affects expression ISO methylselenic acid affects the expression of BUB1B mRNA CTD PMID:14617803 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C1qbp complement C1q binding protein decreases expression ISO methylselenic acid results in decreased expression of C1QBP mRNA CTD PMID:18548127 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G Cadm1 cell adhesion molecule 1 affects expression ISO methylselenic acid affects the expression of CADM1 mRNA CTD PMID:14617803 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Calm1 calmodulin 1 increases expression ISO methylselenic acid results in increased expression of CALM1 mRNA CTD PMID:18548127 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO methylselenic acid results in increased expression of CAMK2G mRNA CTD PMID:18548127 NCBI chr15:3,936,721...3,995,740
Ensembl chr15:3,936,786...3,995,915
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases expression ISO methylselenic acid results in increased expression of CAMK4 mRNA CTD PMID:12517777 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression ISO methylselenic acid results in decreased expression of CAPZA1 mRNA CTD PMID:18548127 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage
ISO HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein] CTD PMID:16204082 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO methylselenic acid results in increased cleavage of and results in increased activity of CASP3 protein
methylselenic acid results in increased cleavage of CASP3 protein
CTD PMID:19276161, PMID:28161410 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases cleavage ISO methylselenic acid results in increased cleavage of CASP4 protein CTD PMID:28161410 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
ISO methylselenic acid results in increased cleavage of CASP7 protein
Acetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]; Sodium Selenite inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; Tamoxifen promotes the reaction [methylselenic acid results in increased cleavage of CASP7 protein]
CTD PMID:16204082, PMID:18790785, PMID:28161410 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP8 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP8 protein
[methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP8 protein
CTD PMID:18444175, PMID:18790785 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP9 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]; methylselenic acid results in increased cleavage of and results in increased activity of CASP9 protein
[methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP9 protein
methylselenic acid results in increased expression of CASP9 mRNA
CTD PMID:12517777, PMID:17339365, PMID:18444175, PMID:18790785, PMID:28161410 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression ISO methylselenic acid results in increased expression of CAST mRNA CTD PMID:18548127 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cbx7 chromobox 7 increases expression ISO methylselenic acid results in increased expression of CBX7 mRNA CTD PMID:18548127 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Cck cholecystokinin increases expression ISO methylselenic acid results in increased expression of CCK mRNA CTD PMID:18548127 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO methylselenic acid results in decreased expression of CCNA2 mRNA CTD PMID:12517777 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO methylselenic acid results in decreased expression of CCNB1 mRNA; methylselenic acid results in decreased expression of CCNB1 protein CTD PMID:11830524 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 affects expression
decreases expression
multiple interactions
ISO
EXP
methylselenic acid affects the expression of CCND1 mRNA
methylselenic acid affects the expression of CCND1 protein
methylselenic acid results in decreased expression of CCND1 mRNA
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of CCND1 protein; KLF4 protein affects the reaction [methylselenic acid results in decreased expression of CCND1 mRNA]; methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]
CTD PMID:11830524, PMID:12017302, PMID:17847021, PMID:18314491, PMID:18444175 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO methylselenic acid results in decreased expression of CCNE2 mRNA CTD PMID:12517777 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cd14 CD14 molecule decreases expression ISO methylselenic acid results in decreased expression of CD14 mRNA CTD PMID:18548127 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO methylselenic acid results in decreased expression of CD44 mRNA CTD PMID:12517777 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdc14b cell division cycle 14B affects expression ISO methylselenic acid affects the expression of CDC14B mRNA CTD PMID:14617803 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750
JBrowse link
G Cdc20 cell division cycle 20 affects expression ISO methylselenic acid affects the expression of CDC20 mRNA CTD PMID:14617803 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25a cell division cycle 25A affects expression
decreases expression
ISO methylselenic acid affects the expression of CDC25A mRNA
methylselenic acid results in decreased expression of CDC25A mRNA; methylselenic acid results in decreased expression of CDC25A protein
CTD PMID:11830524, PMID:14617803 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO methylselenic acid results in decreased expression of CDC25C mRNA CTD PMID:11830524 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO methylselenic acid results in decreased expression of CDC42 mRNA CTD PMID:11830524 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression ISO methylselenic acid results in increased expression of CDC42EP3 mRNA CTD PMID:18548127 NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of CDC6 mRNA
methylselenic acid affects the expression of CDC6 mRNA
CTD PMID:11830524, PMID:14617803 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdh15 cadherin 15 increases expression ISO methylselenic acid results in increased expression of CDH15 mRNA CTD PMID:12517777 NCBI chr19:55,669,661...55,689,986
Ensembl chr19:55,669,626...55,689,992
JBrowse link
G Cdh7 cadherin 7 increases expression ISO methylselenic acid results in increased expression of CDH7 mRNA CTD PMID:12517777 NCBI chr13:31,081,064...31,228,884
Ensembl chr13:31,081,804...31,231,213
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
ISO HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK1 protein]
methylselenic acid results in decreased expression of CDK1 mRNA; methylselenic acid results in decreased expression of CDK1 protein
CTD PMID:11830524, PMID:12517777, PMID:16205645 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression ISO methylselenic acid results in decreased expression of CDK10 mRNA CTD PMID:11830524 NCBI chr19:56,024,903...56,032,610
Ensembl chr19:56,024,903...56,032,605
JBrowse link
G Cdk16 cyclin-dependent kinase 16 decreases expression ISO methylselenic acid results in decreased expression of CDK16 mRNA CTD PMID:12517777 NCBI chr  X:1,707,285...1,718,821
Ensembl chr  X:1,707,289...1,718,637
JBrowse link
G Cdk18 cyclin-dependent kinase 18 increases expression ISO methylselenic acid results in increased expression of CDK18 mRNA CTD PMID:18548127 NCBI chr13:48,893,525...48,926,673
Ensembl chr13:48,893,412...48,927,483
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases expression
ISO HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]
methylselenic acid results in decreased expression of CDK2 mRNA; methylselenic acid results in decreased expression of CDK2 protein
CTD PMID:12517777, PMID:16205645, PMID:17847021 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
decreases expression
ISO methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]
methylselenic acid results in decreased expression of CDK4 mRNA
CTD PMID:11830524, PMID:12517777, PMID:17847021, PMID:18548127 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression ISO methylselenic acid results in increased expression of CDK5 mRNA CTD PMID:11830524 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO methylselenic acid promotes the reaction [CDKN2A protein binds to CDK6 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK6 protein] CTD PMID:17847021 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkl1 cyclin dependent kinase like 1 decreases expression ISO methylselenic acid results in decreased expression of CDKL1 mRNA CTD PMID:11830524 NCBI chr 6:92,076,247...92,123,108
Ensembl chr 6:92,077,416...92,121,351
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects expression
increases expression
ISO
EXP
DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in increased expression of and results in decreased degradation of CDKN1A protein
methylselenic acid affects the expression of CDKN1A protein
methylselenic acid results in increased expression of CDKN1A mRNA; methylselenic acid results in increased expression of CDKN1A protein
methylselenic acid affects the expression of CDKN1A mRNA
CTD PMID:12017302, PMID:12517777, PMID:14617803, PMID:16205645, PMID:17847021, PMID:18314491 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
affects expression
increases expression
ISO
EXP
KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1B mRNA]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]
methylselenic acid affects the expression of CDKN1B protein
methylselenic acid results in increased expression of CDKN1B mRNA; methylselenic acid results in increased expression of CDKN1B protein
CTD PMID:12017302, PMID:17847021, PMID:18314491 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression
affects expression
ISO methylselenic acid results in increased expression of CDKN1C mRNA
methylselenic acid affects the expression of CDKN1C mRNA
CTD PMID:14617803, PMID:18548127 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
increases expression
ISO methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid promotes the reaction [CDKN2A protein binds to CDK6 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK6 protein]
methylselenic acid results in increased expression of CDKN2A protein
CTD PMID:17847021 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cenpa centromere protein A affects expression ISO methylselenic acid affects the expression of CENPA mRNA CTD PMID:14617803 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cenpf centromere protein F decreases expression ISO methylselenic acid results in decreased expression of CENPF mRNA CTD PMID:12517777 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of CFLAR protein CTD PMID:18444175 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO methylselenic acid results in decreased expression of CHAF1A mRNA CTD PMID:12517777 NCBI chr 9:11,000,869...11,027,631
Ensembl chr 9:11,001,129...11,027,506
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO methylselenic acid results in increased expression of CHEK2 mRNA CTD PMID:12517777 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Clu clusterin affects expression ISO methylselenic acid affects the expression of CLU mRNA CTD PMID:14617803 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cnpy2 canopy FGF signaling regulator 2 decreases expression ISO methylselenic acid results in decreased expression of CNPY2 mRNA CTD PMID:18548127 NCBI chr 7:2,737,674...2,744,321
Ensembl chr 7:2,737,765...2,742,369
JBrowse link
G Col16a1 collagen type XVI alpha 1 chain increases expression ISO methylselenic acid results in increased expression of COL16A1 mRNA CTD PMID:18548127 NCBI chr 5:148,257,030...148,311,645
Ensembl chr 5:148,257,642...148,311,645
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO methylselenic acid results in increased expression of COL6A1 mRNA CTD PMID:18548127 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Coro1a coronin 1A increases expression ISO methylselenic acid results in increased expression of CORO1A mRNA CTD PMID:12517777 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO methylselenic acid results in increased expression of CRABP2 mRNA CTD PMID:18548127 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO methylselenic acid results in increased expression of CREB1 mRNA CTD PMID:12517777 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 decreases expression ISO methylselenic acid results in decreased expression of CREB3L1 mRNA CTD PMID:18548127 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 affects expression ISO methylselenic acid affects the expression of CREB3L4 mRNA CTD PMID:14617803 NCBI chr 2:189,596,657...189,602,243
Ensembl chr 2:189,595,415...189,602,143
JBrowse link
G Cryab crystallin, alpha B increases expression ISO methylselenic acid results in increased expression of CRYAB mRNA CTD PMID:18548127 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression ISO methylselenic acid results in increased expression of CSRP1 mRNA CTD PMID:18548127 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Ctsk cathepsin K increases expression ISO methylselenic acid results in increased expression of CTSK mRNA CTD PMID:18548127 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cul1 cullin 1 increases expression ISO methylselenic acid results in increased expression of CUL1 mRNA CTD PMID:18548127 NCBI chr 4:77,211,814...77,283,369
Ensembl chr 4:77,211,692...77,280,250
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression ISO methylselenic acid results in increased expression of CYLD mRNA CTD PMID:18548127 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of DDIT3 protein]
methylselenic acid results in increased expression of DDIT3 mRNA; methylselenic acid results in increased expression of DDIT3 protein
CTD PMID:11830524, PMID:12517777, PMID:16204082, PMID:16205645, PMID:19276161, PMID:28161410 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression ISO methylselenic acid results in decreased expression of DEAF1 mRNA CTD PMID:18548127 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions
decreases expression
ISO AR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA] CTD PMID:16020662, PMID:18548127 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO methylselenic acid results in decreased expression of DHFR mRNA CTD PMID:12517777 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO methylselenic acid results in increased expression of DIXDC1 mRNA CTD PMID:18548127 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression ISO methylselenic acid results in decreased expression of DKC1 mRNA CTD PMID:18548127 NCBI chr  X:155,844,914...155,862,363
Ensembl chr  X:155,844,857...155,862,475
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein increases expression ISO methylselenic acid results in increased expression of DLC1 mRNA CTD PMID:12517777 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression ISO methylselenic acid results in increased expression of DNAJB5 mRNA CTD PMID:18548127 NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 affects expression ISO methylselenic acid affects the expression of DNAJB9 mRNA CTD PMID:14617803 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO methylselenic acid results in decreased expression of DNPH1 mRNA CTD PMID:18548127 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases expression ISO methylselenic acid results in increased expression of DPYD mRNA CTD PMID:18548127 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO methylselenic acid results in increased expression of DPYSL2 mRNA CTD PMID:18548127 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Dtna dystrobrevin, alpha increases expression ISO methylselenic acid results in increased expression of DTNA mRNA CTD PMID:18548127 NCBI chr18:14,544,725...14,671,514
Ensembl chr18:14,471,213...14,657,332
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression ISO methylselenic acid results in decreased expression of DTYMK mRNA CTD PMID:12517777 NCBI chr 9:100,921,565...100,930,399
Ensembl chr 9:100,921,565...100,930,399
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO methylselenic acid results in increased expression of DUSP10 mRNA CTD PMID:12517777 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression ISO methylselenic acid results in increased expression of DVL3 mRNA CTD PMID:18548127 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 increases expression ISO methylselenic acid results in increased expression of DYNC1I1 mRNA CTD PMID:18548127 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G E2f1 E2F transcription factor 1 affects expression
multiple interactions
decreases expression
ISO methylselenic acid affects the expression of E2F1 mRNA
methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein]
methylselenic acid results in decreased expression of E2F1 mRNA; methylselenic acid results in decreased expression of E2F1 protein
CTD PMID:11830524, PMID:14617803, PMID:17847021 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO methylselenic acid results in decreased expression of E2F5 mRNA CTD PMID:11830524 NCBI chr 2:88,350,764...88,366,913
Ensembl chr 2:88,351,361...88,366,115
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 decreases expression ISO methylselenic acid results in decreased expression of ECI1 mRNA CTD PMID:18548127 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO methylselenic acid results in increased expression of ECM2 mRNA CTD PMID:18548127 NCBI chr17:15,533,760...15,566,403
Ensembl chr17:15,533,972...15,566,332
JBrowse link
G Ednra endothelin receptor type A increases expression ISO methylselenic acid results in increased expression of EDNRA mRNA CTD PMID:18548127 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO methylselenic acid results in increased expression of EDNRB mRNA CTD PMID:18548127 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO methylselenic acid results in increased expression of EFEMP2 mRNA CTD PMID:18548127 NCBI chr 1:220,853,695...220,861,420
Ensembl chr 1:220,854,403...220,861,420
JBrowse link
G Egr1 early growth response 1 increases expression ISO methylselenic acid results in increased expression of EGR1 mRNA CTD PMID:11172735 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases phosphorylation
ISO HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2A protein] CTD PMID:16204082 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein]; methylselenic acid results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:16204082, PMID:16205645 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 decreases expression ISO methylselenic acid results in decreased expression of EIF4G2 mRNA CTD PMID:12517777 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression
affects expression
ISO methylselenic acid results in increased expression of ELF3 mRNA
methylselenic acid affects the expression of ELF3 mRNA
CTD PMID:12517777, PMID:14617803 NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
JBrowse link
G Eno2 enolase 2 increases expression ISO methylselenic acid results in increased expression of ENO2 mRNA CTD PMID:18548127 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 increases expression ISO methylselenic acid results in increased expression of EPB41L2 mRNA CTD PMID:18548127 NCBI chr 1:20,881,820...21,067,713
Ensembl chr 1:20,893,995...20,962,526
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO methylselenic acid results in increased expression of EPS8 mRNA CTD PMID:18548127 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression ISO methylselenic acid results in increased expression of ERCC1 mRNA CTD PMID:12517777 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO [methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 mRNA; [methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 protein; methylselenic acid inhibits the reaction [Estradiol binds to ESR1 protein]; methylselenic acid results in decreased expression of and results in decreased activity of ESR1 protein
methylselenic acid results in decreased expression of ESR1 mRNA; methylselenic acid results in decreased expression of ESR1 protein
CTD PMID:15833885, PMID:16093440, PMID:16155795 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases expression
affects expression
ISO methylselenic acid results in increased expression of ESR2 mRNA
methylselenic acid affects the expression of ESR2 mRNA
CTD PMID:15833885, PMID:16928829 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression ISO methylselenic acid results in increased expression of ETV5 mRNA CTD PMID:18548127 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Etv6 ETS variant transcription factor 6 increases expression ISO methylselenic acid results in increased expression of ETV6 mRNA CTD PMID:18548127 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Ext1 exostosin glycosyltransferase 1 increases expression ISO methylselenic acid results in increased expression of EXT1 mRNA CTD PMID:18548127 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression ISO methylselenic acid results in increased expression of FAM107A mRNA CTD PMID:18548127 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Fbxl8 F-box and leucine-rich repeat protein 8 increases expression ISO methylselenic acid results in increased expression of FBXL8 mRNA CTD PMID:18548127 NCBI chr19:37,216,696...37,225,701
Ensembl chr19:37,221,132...37,226,065
JBrowse link
G Fermt2 fermitin family member 2 increases expression ISO methylselenic acid results in increased expression of FERMT2 mRNA CTD PMID:18548127 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression ISO methylselenic acid results in increased expression of FEZ1 mRNA CTD PMID:18548127 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO methylselenic acid results in decreased expression of FGF2 mRNA CTD PMID:12517777 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO methylselenic acid results in increased expression of FHL2 mRNA CTD PMID:18548127 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression ISO methylselenic acid results in decreased expression of FKBP4 mRNA CTD PMID:18548127 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 affects expression ISO methylselenic acid affects the expression of FKBP5 mRNA CTD PMID:14617803 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Flnc filamin C increases expression ISO methylselenic acid results in increased expression of FLNC mRNA CTD PMID:18548127 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fn1 fibronectin 1 affects expression ISO methylselenic acid affects the expression of FN1 mRNA CTD PMID:14617803 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fnbp1 formin binding protein 1 increases expression ISO methylselenic acid results in increased expression of FNBP1 mRNA CTD PMID:18548127 NCBI chr 3:9,865,657...9,936,333
Ensembl chr 3:9,861,237...9,936,405
JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO methylselenic acid results in decreased expression of FOXA1 mRNA CTD PMID:12517777, PMID:18548127 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO methylselenic acid results in decreased phosphorylation of and results in increased activity of FOXO3 protein CTD PMID:17339365 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO methylselenic acid results in increased expression of FYN mRNA CTD PMID:18548127 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO methylselenic acid results in increased expression of GABARAPL1 mRNA CTD PMID:18548127 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO methylselenic acid results in increased expression of GADD45A mRNA CTD PMID:12517777 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO methylselenic acid results in decreased expression of GALNT1 mRNA CTD PMID:18548127 NCBI chr18:16,141,062...16,187,271
Ensembl chr18:16,146,447...16,185,496
JBrowse link
G Gas1 growth arrest-specific 1 increases expression ISO methylselenic acid results in increased expression of GAS1 mRNA CTD PMID:18548127 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A decreases expression ISO methylselenic acid results in decreased expression of GATD3A mRNA CTD PMID:18548127 NCBI chr20:11,244,353...11,252,450
Ensembl chr20:11,244,353...11,252,449
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO methylselenic acid results in increased expression of GBP2 mRNA CTD PMID:18548127 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO methylselenic acid results in increased expression of GJA1 mRNA CTD PMID:18548127 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpr161 G protein-coupled receptor 161 increases expression ISO methylselenic acid results in increased expression of GPR161 mRNA CTD PMID:18548127 NCBI chr13:83,530,389...83,576,117
Ensembl chr13:83,531,018...83,571,505
JBrowse link
G Gpr37 G protein-coupled receptor 37 increases expression ISO methylselenic acid results in increased expression of GPR37 mRNA CTD PMID:12517777 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO methylselenic acid results in increased expression of GRK5 mRNA CTD PMID:18548127 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
ISO methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]
methylselenic acid results in decreased phosphorylation of GSK3B protein
CTD PMID:17339365 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin increases expression ISO methylselenic acid results in increased expression of GSN mRNA CTD PMID:18548127 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 decreases expression ISO methylselenic acid results in decreased expression of GTF3C1 mRNA CTD PMID:18548127 NCBI chr 1:197,032,473...197,098,676
Ensembl chr 1:197,032,474...197,098,649
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 affects expression
decreases expression
multiple interactions
ISO methylselenic acid affects the expression of GUCY1A1 mRNA
methylselenic acid results in decreased expression of GUCY1A1 mRNA
AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A1 mRNA]
CTD PMID:14617803, PMID:16020662, PMID:18548127 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G H1f0 H1 histone family, member 0 affects expression ISO methylselenic acid affects the expression of H1-0 mRNA CTD PMID:14617803 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G Habp4 hyaluronan binding protein 4 increases expression ISO methylselenic acid results in increased expression of HABP4 mRNA CTD PMID:18548127 NCBI chr17:1,679,561...1,702,245
Ensembl chr17:1,679,627...1,701,623
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 decreases expression ISO methylselenic acid results in decreased expression of HACD2 mRNA CTD PMID:18548127 NCBI chr11:68,893,684...68,985,635
Ensembl chr11:68,894,445...68,989,988
JBrowse link
G Heph hephaestin increases expression ISO methylselenic acid results in increased expression of HEPH mRNA CTD PMID:18548127 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression ISO methylselenic acid results in decreased expression of H2AC8 mRNA CTD PMID:18548127 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 decreases expression ISO methylselenic acid results in decreased expression of H2AC18 mRNA CTD PMID:18548127 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hmgn4 high mobility group nucleosomal binding domain 4 increases expression ISO methylselenic acid results in increased expression of HMGN4 mRNA CTD PMID:18548127 NCBI chr 3:104,675,173...104,675,525 JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B decreases expression ISO methylselenic acid results in decreased expression of HNRNPAB mRNA CTD PMID:18548127 NCBI chr10:34,955,713...34,961,662
Ensembl chr10:34,955,716...34,961,608
JBrowse link
G Hoxa9 homeobox A9 decreases expression ISO methylselenic acid results in decreased expression of HOXA9 mRNA CTD PMID:18548127
G Hoxd8 homeobox D8 increases expression ISO methylselenic acid results in increased expression of HOXD8 mRNA CTD PMID:12517777 NCBI chr 3:61,627,329...61,629,743
Ensembl chr 3:61,627,383...61,628,628
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO methylselenic acid results in increased expression of HPGD mRNA; methylselenic acid results in increased expression of HPGD protein CTD PMID:25187657 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO methylselenic acid results in increased expression of HPGDS mRNA CTD PMID:21669866 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression
multiple interactions
ISO methylselenic acid results in increased expression of HSP90B1 protein
HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSP90B1 protein]
CTD PMID:16204082 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO methylselenic acid results in increased expression of HSPA4L mRNA CTD PMID:18548127 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK1 protein]; HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein]; HSPA5 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of DDIT3 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSP90B1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSPA5 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein]; methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]
methylselenic acid results in increased expression of HSPA5 mRNA; methylselenic acid results in increased expression of HSPA5 protein
CTD PMID:16204082, PMID:16205645, PMID:28161410 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO methylselenic acid results in decreased expression of ID1 mRNA CTD PMID:12517777 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id2 inhibitor of DNA binding 2 affects expression ISO methylselenic acid affects the expression of ID2 mRNA CTD PMID:14617803 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression
increases expression
ISO methylselenic acid results in decreased expression of ID3 mRNA
methylselenic acid results in increased expression of ID3 mRNA
CTD PMID:12517777, PMID:18548127 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ids iduronate 2-sulfatase increases expression ISO methylselenic acid results in increased expression of IDS mRNA CTD PMID:18548127 NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 decreases expression ISO methylselenic acid results in decreased expression of IFRD2 mRNA CTD PMID:18548127 NCBI chr 8:116,343,096...116,348,318
Ensembl chr 8:116,343,096...116,348,314
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO methylselenic acid results in increased expression of IGF1 mRNA CTD PMID:11830524 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igsf3 immunoglobulin superfamily, member 3 affects expression ISO methylselenic acid affects the expression of IGSF3 mRNA CTD PMID:14617803 NCBI chr 2:203,768,364...203,855,573
Ensembl chr 2:203,768,117...203,855,573
JBrowse link
G Ing1 inhibitor of growth family, member 1 affects expression ISO methylselenic acid affects the expression of ING1 mRNA CTD PMID:14617803 NCBI chr16:83,277,055...83,278,120
Ensembl chr16:83,276,273...83,278,119
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B affects expression ISO methylselenic acid affects the expression of INPP4B mRNA CTD PMID:14617803 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
JBrowse link
G Ipo8 importin 8 increases expression ISO methylselenic acid results in increased expression of IPO8 mRNA CTD PMID:12517777 NCBI chr 4:183,228,688...183,295,253 JBrowse link
G Irf1 interferon regulatory factor 1 affects expression ISO methylselenic acid affects the expression of IRF1 mRNA CTD PMID:14617803 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO methylselenic acid results in increased expression of ITGA3 mRNA CTD PMID:18548127 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO methylselenic acid results in decreased expression of ITGB1 mRNA CTD PMID:11172735 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein decreases expression ISO methylselenic acid results in decreased expression of ITGB3BP mRNA CTD PMID:12517777 NCBI chr 5:118,476,410...118,541,928
Ensembl chr 5:118,476,430...118,673,780
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO methylselenic acid results in decreased expression of ITGB4 mRNA CTD PMID:12517777 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO methylselenic acid results in decreased expression of ITGB5 mRNA CTD PMID:12517777 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO methylselenic acid results in increased expression of ITPR1 mRNA CTD PMID:18548127 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jak1 Janus kinase 1 affects expression
increases expression
ISO methylselenic acid affects the expression of JAK1 mRNA
methylselenic acid results in increased expression of JAK1 mRNA
CTD PMID:14617803, PMID:18548127 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
affects expression
ISO methylselenic acid results in decreased expression of JUN protein
methylselenic acid affects the expression of JUN mRNA
CTD PMID:11830524 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO methylselenic acid results in decreased expression of JUNB mRNA CTD PMID:12517777 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 increases expression ISO methylselenic acid results in increased expression of KCNAB1 mRNA CTD PMID:18548127 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 increases expression ISO methylselenic acid results in increased expression of KCNH2 mRNA CTD PMID:18548127 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 increases expression ISO methylselenic acid results in increased expression of KCNJ8 mRNA CTD PMID:18548127 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 decreases expression ISO methylselenic acid results in decreased expression of KDELR2 mRNA CTD PMID:18548127 NCBI chr12:13,192,452...13,210,758
Ensembl chr12:13,192,453...13,210,758
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO methylselenic acid results in decreased expression of KIF11 mRNA CTD PMID:12517777 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO methylselenic acid results in decreased expression of KIF20B mRNA CTD PMID:12517777 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions
increases expression
increases activity
affects expression
ISO KLF4 protein affects the reaction [methylselenic acid results in decreased expression of CCND1 mRNA]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1B mRNA]
methylselenic acid results in increased expression of KLF4 mRNA
methylselenic acid results in increased activity of KLF4 protein
methylselenic acid affects the expression of KLF4 mRNA
CTD PMID:14617803, PMID:18314491 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klhl2 kelch-like family member 2 affects expression ISO methylselenic acid affects the expression of KLHL2 mRNA CTD PMID:14617803 NCBI chr16:26,755,246...26,852,134
Ensembl chr16:26,739,389...26,852,179
JBrowse link
G Krt15 keratin 15 increases expression ISO methylselenic acid results in increased expression of KRT15 mRNA CTD PMID:18548127 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt20 keratin 20 increases expression ISO methylselenic acid results in increased expression of KRT20 mRNA CTD PMID:12517777 NCBI chr10:87,342,514...87,351,045
Ensembl chr10:87,342,619...87,351,045
JBrowse link
G Lage3 L antigen family, member 3 decreases expression ISO methylselenic acid results in decreased expression of LAGE3 mRNA CTD PMID:18548127 NCBI chr  X:156,355,376...156,356,799
Ensembl chr  X:156,355,376...156,356,799
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression ISO methylselenic acid results in increased expression of LAMA4 mRNA CTD PMID:18548127 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO methylselenic acid results in increased expression of LAMB3 mRNA CTD PMID:18548127 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lmnb2 lamin B2 decreases expression ISO methylselenic acid results in decreased expression of LMNB2 mRNA CTD PMID:12517777 NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
JBrowse link
G LOC684932 similar to Zinc finger protein 75 increases expression ISO methylselenic acid results in increased expression of ZNF75D mRNA CTD PMID:12517777 NCBI chr  X:72,906,565...72,912,322 JBrowse link
G Lypla1 lysophospholipase 1 decreases expression ISO methylselenic acid results in decreased expression of LYPLA1 mRNA CTD PMID:18548127 NCBI chr 5:14,559,333...14,588,447
Ensembl chr 5:14,559,334...14,588,422
JBrowse link
G Maea macrophage erythroblast attacher, E3 ubiquitin ligase decreases expression ISO methylselenic acid results in decreased expression of MAEA mRNA CTD PMID:18548127 NCBI chr14:82,664,248...82,697,673
Ensembl chr14:82,664,249...82,697,673
JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO methylselenic acid results in increased expression of MAF mRNA CTD PMID:18548127 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
JBrowse link
G Map1b microtubule-associated protein 1B affects expression
increases expression
ISO methylselenic acid affects the expression of MAP1B mRNA
methylselenic acid results in increased expression of MAP1B mRNA
CTD PMID:14617803, PMID:18548127 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression
increases expression
ISO methylselenic acid results in decreased expression of MAP2K1 mRNA
methylselenic acid results in increased expression of MAP2K1 mRNA
CTD PMID:11830524, PMID:12517777 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 increases expression ISO methylselenic acid results in increased expression of MAP2K5 mRNA CTD PMID:12517777 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO methylselenic acid results in increased phosphorylation of MAPK1 protein CTD PMID:15845651 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
increases phosphorylation
ISO methylselenic acid results in increased expression of MAPK3 mRNA
methylselenic acid results in increased phosphorylation of MAPK3 protein
CTD PMID:11830524, PMID:15845651 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO methylselenic acid results in increased expression of MAPK8 mRNA CTD PMID:12517777 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression ISO methylselenic acid results in decreased expression of MAPK9 mRNA CTD PMID:11830524 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO methylselenic acid results in increased expression of MAPRE2 mRNA CTD PMID:18548127 NCBI chr18:14,814,149...15,780,290 JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO methylselenic acid results in decreased expression of MAPT mRNA CTD PMID:12517777 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Maz MYC associated zinc finger protein decreases expression ISO methylselenic acid results in decreased expression of MAZ mRNA CTD PMID:12517777 NCBI chr 1:198,456,699...198,460,126
Ensembl chr 1:198,456,699...198,460,126
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 increases expression ISO methylselenic acid results in increased expression of MBNL2 mRNA CTD PMID:18548127 NCBI chr15:105,640,097...105,797,933
Ensembl chr15:105,640,097...105,797,932
JBrowse link
G Mccc2 methylcrotonoyl-CoA carboxylase 2 decreases expression ISO methylselenic acid results in decreased expression of MCCC2 mRNA CTD PMID:18548127 NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 affects expression ISO methylselenic acid affects the expression of MCM2 mRNA CTD PMID:14617803 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO methylselenic acid results in decreased expression of MCM3 mRNA CTD PMID:12517777 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO methylselenic acid results in decreased expression of MCM5 mRNA CTD PMID:12517777 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of MCM6 mRNA
methylselenic acid affects the expression of MCM6 mRNA
CTD PMID:12517777, PMID:14617803 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO methylselenic acid results in decreased expression of MCM7 mRNA CTD PMID:12517777 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Me1 malic enzyme 1 increases expression ISO methylselenic acid results in increased expression of ME1 mRNA CTD PMID:18548127 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO methylselenic acid results in increased expression of MEF2C mRNA CTD PMID:18548127 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Men1 menin 1 affects expression ISO methylselenic acid affects the expression of MEN1 mRNA CTD PMID:14617803 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Micu2 mitochondrial calcium uptake 2 decreases expression ISO methylselenic acid results in decreased expression of MICU2 mRNA CTD PMID:18548127 NCBI chr15:38,191,506...38,276,159
Ensembl chr15:38,191,490...38,276,159
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO methylselenic acid results in increased expression of MITF mRNA CTD PMID:18548127 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO methylselenic acid results in decreased expression of MKI67 mRNA CTD PMID:12517777 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 decreases expression ISO methylselenic acid results in decreased expression of MRPL19 mRNA CTD PMID:18548127 NCBI chr 4:112,703,041...112,707,270
Ensembl chr 4:112,703,041...112,707,270
JBrowse link
G Mxd1 max dimerization protein 1 affects expression ISO methylselenic acid affects the expression of MXD1 mRNA CTD PMID:14617803 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO methylselenic acid results in increased expression of MXI1 mRNA CTD PMID:18548127 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO methylselenic acid results in decreased expression of MYBL2 mRNA CTD PMID:12517777 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression
multiple interactions
ISO methylselenic acid affects the expression of MYC mRNA
methylselenic acid inhibits the reaction [afimoxifene results in increased expression of MYC mRNA]; methylselenic acid inhibits the reaction [Estradiol results in increased expression of MYC mRNA]
CTD PMID:14617803, PMID:15833885, PMID:16093440, PMID:16155795 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myl9 myosin light chain 9 increases expression ISO methylselenic acid results in increased expression of MYL9 mRNA CTD PMID:18548127 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Myo10 myosin X decreases expression ISO methylselenic acid results in decreased expression of MYO10 mRNA CTD PMID:18548127 NCBI chr 2:77,868,398...78,072,443
Ensembl chr 2:77,868,412...78,071,309
JBrowse link
G Myrip myosin VIIA and Rab interacting protein decreases expression ISO methylselenic acid results in decreased expression of MYRIP mRNA CTD PMID:18548127 NCBI chr 8:128,972,307...129,139,257
Ensembl chr 8:128,972,311...129,139,251
JBrowse link
G Naaa N-acylethanolamine acid amidase decreases expression ISO methylselenic acid results in decreased expression of NAAA mRNA CTD PMID:18548127 NCBI chr14:17,283,262...17,302,364
Ensembl chr14:17,283,124...17,302,366
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA1 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA2 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone inhibits the reaction [NCOR1 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO methylselenic acid inhibits the reaction [Dihydrotestosterone inhibits the reaction [NCOR2 protein binds to KLK3 promoter]] CTD PMID:16648561 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ndrg1 N-myc downstream regulated 1 affects expression ISO methylselenic acid affects the expression of NDRG1 mRNA CTD PMID:14617803 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nebl nebulette increases expression ISO methylselenic acid results in increased expression of NEBL mRNA CTD PMID:18548127 NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated affects expression ISO methylselenic acid affects the expression of NFIL3 mRNA CTD PMID:14617803 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO methylselenic acid results in decreased expression of NFKB1 mRNA CTD PMID:12517777 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nkx3-1 NK3 homeobox 1 affects expression ISO methylselenic acid affects the expression of NKX3-1 mRNA CTD PMID:14617803 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression ISO methylselenic acid results in decreased expression of NME1 mRNA CTD PMID:18548127 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 decreases expression ISO methylselenic acid results in decreased expression of NME4 mRNA CTD PMID:18548127 NCBI chr10:15,461,567...15,465,422
Ensembl chr10:15,431,638...15,465,413
JBrowse link
G Nmi N-myc (and STAT) interactor decreases expression ISO methylselenic acid results in decreased expression of NMI mRNA CTD PMID:12517777 NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity ISO methylselenic acid results in increased activity of NQO1 protein CTD PMID:14617803 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO methylselenic acid affects the expression of NR3C1 mRNA CTD PMID:16928829 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Oat ornithine aminotransferase increases expression ISO methylselenic acid results in increased expression of OAT mRNA CTD PMID:18548127 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Olfml2a olfactomedin-like 2A increases expression ISO methylselenic acid results in increased expression of OLFML2A mRNA CTD PMID:18548127 NCBI chr 3:23,223,468...23,259,318
Ensembl chr 3:23,223,479...23,259,321
JBrowse link
G Optn optineurin increases expression ISO methylselenic acid results in increased expression of OPTN mRNA CTD PMID:18548127 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of PARP1 protein; [Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]; SB 216763 inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein] CTD PMID:15845651, PMID:16204082, PMID:17339365, PMID:18444175, PMID:19276161, PMID:28161410 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Patz1 POZ (BTB) and AT hook containing zinc finger 1 decreases expression ISO methylselenic acid results in decreased expression of PATZ1 mRNA CTD PMID:12517777 NCBI chr14:83,509,763...83,528,898
Ensembl chr14:83,510,278...83,528,898
JBrowse link
G Paxip1 PAX interacting protein 1 decreases expression ISO methylselenic acid results in decreased expression of PAXIP1 mRNA CTD PMID:18548127 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326
JBrowse link
G Pbx1 PBX homeobox 1 increases expression ISO methylselenic acid results in increased expression of PBX1 mRNA CTD PMID:18548127 NCBI chr13:86,390,741...86,671,460
Ensembl chr13:86,390,741...86,451,002
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 decreases expression ISO methylselenic acid results in decreased expression of PCBD1 mRNA CTD PMID:18548127 NCBI chr20:30,689,690...30,696,465
Ensembl chr20:30,690,810...30,696,476
JBrowse link
G Pcna proliferating cell nuclear antigen affects expression
decreases expression
ISO methylselenic acid affects the expression of PCNA mRNA
methylselenic acid results in decreased expression of PCNA mRNA
CTD PMID:11830524, PMID:12517777, PMID:14617803 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Peg3 paternally expressed 3 affects expression ISO methylselenic acid affects the expression of PEG3 mRNA CTD PMID:14617803 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pfdn5 prefoldin subunit 5 decreases expression ISO methylselenic acid results in decreased expression of PFDN5 mRNA CTD PMID:11830524 NCBI chr 7:143,924,662...143,929,400
Ensembl chr 7:143,924,662...143,929,397
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression ISO methylselenic acid results in decreased expression of PGAP2 mRNA CTD PMID:18548127 NCBI chr 1:167,309,021...167,335,550
Ensembl chr 1:167,309,051...167,334,741
JBrowse link
G Pgm5 phosphoglucomutase 5 increases expression ISO methylselenic acid results in increased expression of PGM5 mRNA CTD PMID:18548127 NCBI chr 1:242,582,591...242,765,837
Ensembl chr 1:242,582,642...242,765,807
JBrowse link
G Pgr progesterone receptor affects expression ISO methylselenic acid affects the expression of PGR mRNA CTD PMID:16928829 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 increases expression ISO methylselenic acid results in increased expression of PJA2 mRNA CTD PMID:18548127 NCBI chr 9:111,998,204...112,048,847
Ensembl chr 9:111,998,203...112,027,240
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression ISO methylselenic acid results in increased expression of PLA2G4A mRNA CTD PMID:18548127 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plcb4 phospholipase C, beta 4 increases expression ISO methylselenic acid results in increased expression of PLCB4 mRNA CTD PMID:12517777 NCBI chr 3:128,601,163...128,971,720
Ensembl chr 3:128,756,799...128,971,746
JBrowse link
G Plk1 polo-like kinase 1 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of PLK1 mRNA
methylselenic acid affects the expression of PLK1 mRNA
CTD PMID:11830524, PMID:14617803 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component increases expression ISO methylselenic acid results in increased expression of PMS2 mRNA CTD PMID:12517777 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO methylselenic acid results in decreased expression of POLA1 mRNA CTD PMID:12517777 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Polr2h RNA polymerase II, I and III subunit H decreases expression ISO methylselenic acid results in decreased expression of POLR2H mRNA CTD PMID:18548127 NCBI chr11:83,877,760...83,882,208
Ensembl chr11:83,878,006...83,882,117
JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 affects expression ISO methylselenic acid affects the expression of PPFIA1 mRNA CTD PMID:14617803 NCBI chr 1:217,644,259...217,721,285
Ensembl chr 1:217,644,224...217,721,376
JBrowse link
G Ppil2 peptidylprolyl isomerase like 2 decreases expression ISO methylselenic acid results in decreased expression of PPIL2 mRNA CTD PMID:18548127 NCBI chr11:88,147,342...88,169,968
Ensembl chr11:88,147,377...88,169,968
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B increases expression ISO methylselenic acid results in increased expression of PPM1B mRNA CTD PMID:12517777 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO methylselenic acid results in increased expression of PPP1R15A mRNA CTD PMID:28161410 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta increases expression ISO methylselenic acid results in increased expression of PRKAR2B mRNA CTD PMID:18548127 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Prkca protein kinase C, alpha increases expression ISO methylselenic acid results in increased expression of PRKCA mRNA CTD PMID:12517777 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO methylselenic acid results in increased expression of PRKCB mRNA CTD PMID:18548127 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prnp prion protein increases expression ISO methylselenic acid results in increased expression of PRNP mRNA CTD PMID:18548127 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO methylselenic acid results in increased expression of PTEN mRNA CTD PMID:12517777 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO methylselenic acid results in decreased expression of PTGES mRNA CTD PMID:11830524, PMID:21669866 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Qk quaking increases expression ISO methylselenic acid results in increased expression of QKI mRNA CTD PMID:18548127 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression ISO methylselenic acid results in increased expression of RAB28 mRNA CTD PMID:12517777 NCBI chr14:73,888,968...73,963,209
Ensembl chr14:73,889,213...73,963,202
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression
affects expression
ISO methylselenic acid results in increased expression of RAB31 mRNA
methylselenic acid affects the expression of RAB31 mRNA
CTD PMID:12517777, PMID:14617803, PMID:18548127 NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
JBrowse link
G Rabac1 Rab acceptor 1 decreases expression ISO methylselenic acid results in decreased expression of RABAC1 mRNA CTD PMID:12517777 NCBI chr 1:81,843,667...81,846,765
Ensembl chr 1:81,843,649...81,846,804
JBrowse link
G Rad9a RAD9 checkpoint clamp component A increases expression ISO methylselenic acid results in increased expression of RAD9A mRNA CTD PMID:12517777 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression ISO methylselenic acid results in increased expression of RAPGEF4 mRNA CTD PMID:12517777 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein]; methylselenic acid results in decreased phosphorylation of and results in increased expression of RB1 protein CTD PMID:17847021 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rdh11 retinol dehydrogenase 11 affects expression ISO methylselenic acid affects the expression of RDH11 mRNA CTD PMID:14617803 NCBI chr 6:102,356,498...102,372,618
Ensembl chr 6:102,356,492...102,372,611
JBrowse link
G Reep1 receptor accessory protein 1 increases expression ISO methylselenic acid results in increased expression of REEP1 mRNA CTD PMID:18548127 NCBI chr 4:99,618,622...99,735,329
Ensembl chr 4:99,618,622...99,735,319
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO methylselenic acid results in decreased expression of RFC5 mRNA CTD PMID:11830524 NCBI chr12:44,931,494...44,941,051
Ensembl chr12:44,931,494...44,941,324
JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 increases expression ISO methylselenic acid results in increased expression of RGL1 mRNA CTD PMID:18548127 NCBI chr13:69,909,122...70,174,590
Ensembl chr13:69,909,096...70,174,565
JBrowse link
G Rgs10 regulator of G-protein signaling 10 increases expression ISO methylselenic acid results in increased expression of RGS10 mRNA CTD PMID:12517777 NCBI chr 1:199,782,076...199,823,440
Ensembl chr 1:199,782,078...199,823,386
JBrowse link
G Rhob ras homolog family member B affects expression ISO methylselenic acid affects the expression of RHOB mRNA CTD PMID:14617803 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 increases expression ISO methylselenic acid results in increased expression of RIMS3 mRNA CTD PMID:18548127 NCBI chr 5:139,790,395...139,819,014
Ensembl chr 5:139,783,951...139,819,016
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression ISO methylselenic acid results in increased expression of RND3 mRNA CTD PMID:18548127 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Rpa2 replication protein A2 decreases expression ISO methylselenic acid results in decreased expression of RPA2 mRNA CTD PMID:12517777 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269
JBrowse link
G Rpia ribose 5-phosphate isomerase A decreases expression ISO methylselenic acid results in decreased expression of RPIA mRNA CTD PMID:18548127 NCBI chr 4:98,568,028...98,593,664
Ensembl chr 4:98,568,028...98,593,664
JBrowse link
G Rpl27a ribosomal protein L27a decreases expression ISO methylselenic acid results in decreased expression of RPL27A mRNA CTD PMID:18548127 NCBI chr 1:174,132,798...174,135,816
Ensembl chr 1:174,132,798...174,135,816
JBrowse link
G Rpsa ribosomal protein SA decreases expression ISO methylselenic acid results in decreased expression of RPSA mRNA CTD PMID:11172735 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 affects expression ISO methylselenic acid affects the expression of RRM1 mRNA CTD PMID:14617803 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 affects expression ISO methylselenic acid affects the expression of RRM2 mRNA CTD PMID:14617803 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Rxylt1 ribitol xylosyltransferase 1 decreases expression ISO methylselenic acid results in decreased expression of RXYLT1 mRNA CTD PMID:18548127 NCBI chr 7:64,329,341...64,341,201
Ensembl chr 7:64,326,465...64,341,207
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO methylselenic acid results in increased expression of S100A4 mRNA CTD PMID:18548127 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G Samd4a sterile alpha motif domain containing 4A increases expression ISO methylselenic acid results in increased expression of SAMD4 mRNA CTD PMID:18548127 NCBI chr15:23,666,543...23,879,067
Ensembl chr15:23,665,202...23,878,539
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects expression ISO methylselenic acid affects the expression of SAT1 mRNA CTD PMID:14617803 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scd stearoyl-CoA desaturase affects expression ISO methylselenic acid affects the expression of SCD mRNA CTD PMID:14617803 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sdc2 syndecan 2 increases expression ISO methylselenic acid results in increased expression of SDC2 mRNA CTD PMID:18548127 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044
JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component affects expression ISO methylselenic acid affects the expression of SEC24D mRNA CTD PMID:14617803 NCBI chr 2:227,455,704...227,562,801
Ensembl chr 2:227,455,722...227,562,319
JBrowse link
G Sema5a semaphorin 5A increases expression ISO methylselenic acid results in increased expression of SEMA5A mRNA CTD PMID:18548127 NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
JBrowse link
G Serpinb5 serpin family B member 5 increases expression
affects expression
ISO methylselenic acid results in increased expression of SERPINB5 mRNA
methylselenic acid affects the expression of SERPINB5 mRNA
CTD PMID:14617803, PMID:18548127 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Serpinb6a serpin family B member 6A decreases expression ISO methylselenic acid results in decreased expression of SERPINB6 mRNA CTD PMID:18548127 NCBI chr17:32,154,747...32,209,598
Ensembl chr17:32,190,801...32,209,590
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO methylselenic acid results in increased expression of SERPINE2 mRNA CTD PMID:18548127 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Serpinf1 serpin family F member 1 increases expression ISO methylselenic acid results in increased expression of SERPINF1 mRNA CTD PMID:18548127 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 affects expression ISO methylselenic acid affects the expression of SGK1 mRNA CTD PMID:14617803 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sh3bgr SH3 domain binding glutamate-rich protein increases expression ISO methylselenic acid results in increased expression of SH3BGR mRNA CTD PMID:18548127 NCBI chr11:36,555,354...36,579,537
Ensembl chr11:36,555,416...36,579,535
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 affects expression ISO methylselenic acid affects the expression of SH3BP5 mRNA CTD PMID:14617803 NCBI chr16:7,473,367...7,559,976
Ensembl chr16:7,473,370...7,538,201
JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) increases expression ISO methylselenic acid results in increased expression of SLC14A1 mRNA CTD PMID:18548127 NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139
JBrowse link
G Slc16a7 solute carrier family 16 member 7 increases expression ISO methylselenic acid results in increased expression of SLC16A7 mRNA CTD PMID:18548127 NCBI chr 7:68,438,341...68,606,312
Ensembl chr 7:68,446,193...68,549,763
JBrowse link
G Slc19a1 solute carrier family 19 member 1 decreases expression ISO methylselenic acid results in decreased expression of SLC19A1 mRNA CTD PMID:18548127 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
JBrowse link
G Smad7 SMAD family member 7 increases expression ISO methylselenic acid results in increased expression of SMAD7 mRNA CTD PMID:18548127 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 decreases expression ISO methylselenic acid results in decreased expression of SMARCA4 mRNA CTD PMID:18548127 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 increases expression ISO methylselenic acid results in increased expression of SMARCD3 mRNA CTD PMID:18548127 NCBI chr 4:7,076,710...7,108,334
Ensembl chr 4:7,076,759...7,108,328
JBrowse link
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 decreases expression ISO methylselenic acid results in decreased expression of SMARCE1 mRNA CTD PMID:12517777 NCBI chr10:87,116,827...87,138,890
Ensembl chr10:87,116,827...87,137,965
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO methylselenic acid results in increased expression of SNAI2 mRNA CTD PMID:18548127 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Snap25 synaptosome associated protein 25 increases expression ISO methylselenic acid results in increased expression of SNAP25 mRNA CTD PMID:18548127 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Sncg synuclein, gamma increases expression ISO methylselenic acid results in increased expression of SNCG mRNA CTD PMID:18548127 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 decreases expression ISO methylselenic acid results in decreased expression of SND1 mRNA CTD PMID:18548127 NCBI chr 4:55,772,377...56,171,669
Ensembl chr 4:55,772,377...56,171,668
JBrowse link
G Snx1 sorting nexin 1 increases expression ISO methylselenic acid results in increased expression of SNX1 mRNA CTD PMID:18548127 NCBI chr 8:71,745,687...71,786,182
Ensembl chr 8:71,745,896...71,784,551
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 increases expression ISO methylselenic acid results in increased expression of SORBS1 mRNA CTD PMID:18548127 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO methylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter] CTD PMID:17876054 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor increases expression ISO methylselenic acid results in increased expression of SPDEF protein CTD PMID:18567002 NCBI chr20:7,292,823...7,308,053
Ensembl chr20:7,292,824...7,307,284
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression ISO methylselenic acid results in increased expression of SPTAN1 mRNA CTD PMID:18548127 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Srp19 signal recognition particle 19 decreases expression ISO methylselenic acid results in decreased expression of SRP19 mRNA CTD PMID:18548127 NCBI chr18:27,114,822...27,121,062
Ensembl chr18:27,114,822...27,121,059
JBrowse link
G Ssbp2 single-stranded DNA binding protein 2 increases expression ISO methylselenic acid results in increased expression of SSBP2 mRNA CTD PMID:18548127 NCBI chr 2:20,416,795...20,707,838
Ensembl chr 2:20,431,243...20,702,515
JBrowse link
G ST7 suppression of tumorigenicity 7 decreases expression
affects expression
ISO methylselenic acid results in decreased expression of ST7 mRNA
methylselenic acid affects the expression of ST7 mRNA
CTD PMID:14617803, PMID:18548127 NCBI chr 4:45,000,223...45,247,793
Ensembl chr 4:45,000,973...45,247,790
JBrowse link
G Stom stomatin increases expression ISO methylselenic acid results in increased expression of STOM mRNA CTD PMID:18548127 NCBI chr 3:14,515,576...14,538,199
Ensembl chr 3:14,514,868...14,538,241
JBrowse link
G Stx12 syntaxin 12 increases expression ISO methylselenic acid results in increased expression of STX12 mRNA CTD PMID:18548127 NCBI chr 5:151,044,050...151,072,893
Ensembl chr 5:151,044,329...151,072,904
JBrowse link
G Stx1a syntaxin 1A affects expression ISO methylselenic acid affects the expression of STX1A mRNA CTD PMID:14617803 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stx2 syntaxin 2 increases expression ISO methylselenic acid results in increased expression of STX2 mRNA CTD PMID:18548127 NCBI chr12:31,324,203...31,360,249
Ensembl chr12:31,335,372...31,360,254
JBrowse link
G Svil supervillin increases expression ISO methylselenic acid results in increased expression of SVIL mRNA CTD PMID:18548127 NCBI chr17:55,230,298...55,425,967
Ensembl chr17:55,230,298...55,346,279
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 decreases expression ISO methylselenic acid results in decreased expression of TACSTD2 mRNA CTD PMID:18548127 NCBI chr 4:98,341,187...98,342,887
Ensembl chr 4:98,341,188...98,342,887
JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex decreases expression ISO methylselenic acid results in decreased expression of TARBP2 mRNA CTD PMID:18548127 NCBI chr 7:144,121,688...144,126,860
Ensembl chr 7:144,121,744...144,126,857
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked increases expression ISO methylselenic acid results in increased expression of TBL1X mRNA CTD PMID:18548127 NCBI chr  X:44,959,883...44,988,551
Ensembl chr  X:44,830,849...44,988,551
JBrowse link
G Tbxas1 thromboxane A synthase 1 decreases expression ISO methylselenic acid results in decreased expression of TBXAS1 mRNA CTD PMID:21669866 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tcn2 transcobalamin 2 increases expression ISO methylselenic acid results in increased expression of TCN2 mRNA CTD PMID:18548127 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO methylselenic acid inhibits the reaction [afimoxifene results in increased expression of TFF1 mRNA]; methylselenic acid inhibits the reaction [Estradiol results in increased expression of TFF1 mRNA] CTD PMID:16093440, PMID:16155795 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO methylselenic acid results in increased expression of TGFB1 mRNA CTD PMID:12517777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO methylselenic acid results in increased expression of TGFB2 mRNA CTD PMID:18548127 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO methylselenic acid results in increased expression of TGFBR2 mRNA CTD PMID:18548127 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 increases expression ISO methylselenic acid results in increased expression of TGFBR3 mRNA CTD PMID:12517777, PMID:18548127 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Tle2 TLE family member 2, transcriptional corepressor increases expression ISO methylselenic acid results in increased expression of TLE2 mRNA CTD PMID:18548127 NCBI chr 7:10,988,536...11,003,957
Ensembl chr 7:10,988,532...11,003,785
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO methylselenic acid results in increased expression of TLR2 mRNA CTD PMID:12517777 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tmprss2 transmembrane serine protease 2 affects expression ISO methylselenic acid affects the expression of TMPRSS2 mRNA CTD PMID:14617803 NCBI chr11:38,063,914...38,103,406
Ensembl chr11:38,063,915...38,103,290
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 affects expression ISO methylselenic acid affects the expression of TNFAIP3 mRNA CTD PMID:14617803 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO methylselenic acid results in increased expression of TNFRSF25 mRNA CTD PMID:11830524 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Top2a DNA topoisomerase II alpha affects expression ISO methylselenic acid affects the expression of TOP2A mRNA CTD PMID:14617803 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tor1aip1 torsin 1A interacting protein 1 increases expression ISO methylselenic acid results in increased expression of TOR1AIP1 mRNA CTD PMID:18548127 NCBI chr13:73,670,649...73,704,668
Ensembl chr13:73,670,141...73,704,678
JBrowse link
G Tpm1 tropomyosin 1 increases expression ISO methylselenic acid results in increased expression of TPM1 mRNA CTD PMID:18548127 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Trib1 tribbles pseudokinase 1 decreases expression ISO methylselenic acid results in decreased expression of TRIB1 mRNA CTD PMID:18548127 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Trim14 tripartite motif-containing 14 decreases expression ISO methylselenic acid results in decreased expression of TRIM14 mRNA CTD PMID:18548127 NCBI chr 5:62,128,941...62,154,424
Ensembl chr 5:62,128,941...62,153,786
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO methylselenic acid results in decreased expression of TTK mRNA CTD PMID:18548127 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases metabolic processing ISO TXNRD1 protein results in increased metabolism of methylselenic acid CTD PMID:11782468 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyms thymidylate synthetase decreases expression
affects expression
ISO methylselenic acid results in decreased expression of TYMS mRNA
methylselenic acid affects the expression of TYMS mRNA
CTD PMID:12517777, PMID:14617803 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Uck2 uridine-cytidine kinase 2 decreases expression ISO methylselenic acid results in decreased expression of UCK2 mRNA CTD PMID:18548127 NCBI chr13:85,376,716...85,443,976
Ensembl chr13:85,376,716...85,443,976
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO methylselenic acid affects the expression of UGDH mRNA CTD PMID:14617803 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Utrn utrophin decreases expression ISO methylselenic acid results in decreased expression of UTRN mRNA CTD PMID:18548127 NCBI chr 1:6,451,809...6,970,040
Ensembl chr 1:6,451,810...6,970,040
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 increases expression ISO methylselenic acid results in increased expression of VAMP3 mRNA CTD PMID:18548127 NCBI chr 5:168,126,157...168,136,628
Ensembl chr 5:168,126,157...168,136,666
JBrowse link
G Vdr vitamin D receptor affects expression ISO methylselenic acid affects the expression of VDR mRNA CTD PMID:16928829 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression ISO methylselenic acid results in decreased expression of VEGFC mRNA CTD PMID:12517777 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
G Vim vimentin increases expression ISO methylselenic acid results in increased expression of VIM mRNA CTD PMID:18548127 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Wasf1 WASP family member 1 affects expression ISO methylselenic acid affects the expression of WASF1 mRNA CTD PMID:14617803 NCBI chr20:48,456,191...48,503,768
Ensembl chr20:48,455,705...48,503,898
JBrowse link
G Wnt7a Wnt family member 7A decreases expression ISO methylselenic acid results in decreased expression of WNT7A mRNA CTD PMID:12517777 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 decreases expression ISO methylselenic acid results in decreased expression of WSB2 mRNA CTD PMID:18548127 NCBI chr12:44,941,655...44,962,679
Ensembl chr12:44,942,443...44,962,656
JBrowse link
G Xbp1 X-box binding protein 1 increases splicing ISO methylselenic acid results in increased splicing of XBP1 mRNA CTD PMID:16205645, PMID:28161410 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon decreases expression ISO methylselenic acid results in decreased expression of YWHAE mRNA CTD PMID:18548127 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
G Zcchc24 zinc finger CCHC-type containing 24 increases expression ISO methylselenic acid results in increased expression of ZCCHC24 mRNA CTD PMID:18548127 NCBI chr16:1,996,540...2,048,292
Ensembl chr16:1,996,540...2,048,292
JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO methylselenic acid results in increased expression of ZNF274 mRNA CTD PMID:12517777 NCBI chr 1:65,741,769...65,757,709
Ensembl chr 1:65,742,089...65,756,528
JBrowse link
G Zfp217 zinc finger protein 217 increases expression ISO methylselenic acid results in increased expression of ZNF217 mRNA CTD PMID:12517777 NCBI chr 3:166,981,419...167,022,349
Ensembl chr 3:166,983,220...166,994,286
JBrowse link
G Zfp24 zinc finger protein 24 decreases expression ISO methylselenic acid results in decreased expression of ZNF24 mRNA CTD PMID:18548127 NCBI chr18:15,910,175...15,921,757
Ensembl chr18:15,914,399...15,921,734
JBrowse link
G Zfp267 zinc finger protein 267 increases expression ISO methylselenic acid results in increased expression of ZNF267 mRNA CTD PMID:12517777 NCBI chr 2:122,855,036...122,873,696
Ensembl chr 2:122,865,100...122,869,616
JBrowse link
G Zfp458 zinc finger protein 458 decreases expression ISO methylselenic acid results in decreased expression of ZNF43 mRNA CTD PMID:18548127 NCBI chr 2:86,971,129...86,980,519
Ensembl chr 2:86,971,147...86,980,515
JBrowse link
Se-methyl-L-selenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
decreases expression
EXP Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Ar androgen receptor decreases expression ISO
EXP
selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA
CTD PMID:16637076, PMID:19025659 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP selenomethylselenocysteine results in decreased expression of ARNTL mRNA CTD PMID:19122877 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Banp Btg3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr19:54,766,441...54,843,795
Ensembl chr19:54,766,589...54,840,569
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of BCL2 mRNA
selenomethylselenocysteine results in decreased expression of BCL2 protein
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
CTD PMID:11396176, PMID:19360359 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bmf Bcl2 modifying factor multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; C646 compound inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF protein
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein
CTD PMID:25321483 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO selenomethylselenocysteine results in increased activity of CASP3 protein
selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]
CTD PMID:15318939, PMID:25321483 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]
CTD PMID:25321483 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein
CTD PMID:11396176, PMID:18855134, PMID:19276161 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein
CTD PMID:25321483 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176, PMID:19276161 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression EXP selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1 CTD PMID:15897249 NCBI chr14:83,460,540...83,476,568
Ensembl chr14:83,460,540...83,476,568
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of ESR1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein
CTD PMID:18855134 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Faslg Fas ligand multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG CTD PMID:15897249 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO selenomethylselenocysteine results in increased expression of GADD45A mRNA CTD PMID:10656618 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity
increases expression
ISO selenomethylselenocysteine results in increased activity of GPX1 protein
selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein
CTD PMID:18514395, PMID:19033020 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO selenomethylselenocysteine results in increased expression of GPX4 mRNA CTD PMID:18514395 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK1 mRNA CTD PMID:18514395 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK3 mRNA CTD PMID:18514395 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP selenomethylselenocysteine results in increased phosphorylation of JUN protein CTD PMID:19276161 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of KLK3 protein CTD PMID:16637076 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
decreases expression
ISO [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein
selenomethylselenocysteine results in decreased expression of MKI67 protein
CTD PMID:18855134 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO selenomethylselenocysteine results in increased expression of MSRB1 mRNA CTD PMID:18514395 NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21213327 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21213327 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO selenomethylselenocysteine results in increased expression of P4HA1 mRNA CTD PMID:18514395 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form] CTD PMID:25321483 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Per2 period circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of PER2 mRNA CTD PMID:19122877 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Per3 period circadian regulator 3 increases expression EXP selenomethylselenocysteine results in increased expression of PER3 mRNA CTD PMID:19122877 NCBI chr 5:168,088,126...168,123,482
Ensembl chr 5:168,086,998...168,123,395
JBrowse link
G Pgr progesterone receptor decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of PGR protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein
CTD PMID:18855134 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO selenomethylselenocysteine results in increased expression of PPP1R15A mRNA CTD PMID:10656618 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCE protein CTD PMID:10656618 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcz protein kinase C, zeta decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCZ protein CTD PMID:10656618 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB3B mRNA CTD PMID:18514395 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB4A mRNA CTD PMID:18514395 NCBI chr19:56,585,598...56,613,078
Ensembl chr19:56,585,767...56,613,075
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:21213327 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO selenomethylselenocysteine results in increased expression of SCARB1 mRNA CTD PMID:18514395 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selenof selenoprotein F increases expression ISO selenomethylselenocysteine results in increased expression of SELENOF mRNA CTD PMID:18514395 NCBI chr 2:250,600,823...250,633,903
Ensembl chr 2:250,600,823...250,633,897
JBrowse link
G Selenop selenoprotein P increases expression ISO selenomethylselenocysteine results in increased expression of SELENOP mRNA CTD PMID:18514395 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Selenow selenoprotein W increases expression ISO selenomethylselenocysteine results in increased expression of SELENOW mRNA CTD PMID:18514395 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 6:8,284,937...8,318,649
Ensembl chr 6:8,284,878...8,318,674
JBrowse link
G Slc6a19 solute carrier family 6 member 19 increases uptake ISO SLC6A19 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 1:32,199,869...32,218,628
Ensembl chr 1:32,199,810...32,220,045
JBrowse link
G Snap23 synaptosome associated protein 23 decreases expression ISO selenomethylselenocysteine results in decreased expression of SNAP23 mRNA CTD PMID:18514395 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Sort1 sortilin 1 increases expression ISO selenomethylselenocysteine results in increased expression of SORT1 mRNA CTD PMID:18514395 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 3:59,644,579...59,689,011
Ensembl chr 3:59,646,015...59,688,692
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions EXP [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein CTD PMID:19025659 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein CTD PMID:19360359 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 increases expression ISO selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA CTD PMID:18514395 NCBI chr 5:150,463,797...150,506,803
Ensembl chr 5:150,492,587...150,506,871
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
Se-methylselenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
decreases expression
EXP Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Ar androgen receptor decreases expression ISO
EXP
selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA
CTD PMID:16637076, PMID:19025659 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP selenomethylselenocysteine results in decreased expression of ARNTL mRNA CTD PMID:19122877 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Banp Btg3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr19:54,766,441...54,843,795
Ensembl chr19:54,766,589...54,840,569
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of BCL2 mRNA
selenomethylselenocysteine results in decreased expression of BCL2 protein
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
CTD PMID:11396176, PMID:19360359 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bmf Bcl2 modifying factor multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; C646 compound inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF protein
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein
CTD PMID:25321483 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO selenomethylselenocysteine results in increased activity of CASP3 protein
selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]
CTD PMID:15318939, PMID:25321483 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]
CTD PMID:25321483 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein
CTD PMID:11396176, PMID:18855134, PMID:19276161 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein
CTD PMID:25321483 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176, PMID:19276161 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression EXP selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1 CTD PMID:15897249 NCBI chr14:83,460,540...83,476,568
Ensembl chr14:83,460,540...83,476,568
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of ESR1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein
CTD PMID:18855134 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Faslg Fas ligand multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG CTD PMID:15897249 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO selenomethylselenocysteine results in increased expression of GADD45A mRNA CTD PMID:10656618 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity
increases expression
ISO selenomethylselenocysteine results in increased activity of GPX1 protein
selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein
CTD PMID:18514395, PMID:19033020 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO selenomethylselenocysteine results in increased expression of GPX4 mRNA CTD PMID:18514395 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK1 mRNA CTD PMID:18514395 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK3 mRNA CTD PMID:18514395 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP selenomethylselenocysteine results in increased phosphorylation of JUN protein CTD PMID:19276161 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of KLK3 protein CTD PMID:16637076 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
decreases expression
ISO [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein
selenomethylselenocysteine results in decreased expression of MKI67 protein
CTD PMID:18855134 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO selenomethylselenocysteine results in increased expression of MSRB1 mRNA CTD PMID:18514395 NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21213327 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21213327 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO selenomethylselenocysteine results in increased expression of P4HA1 mRNA CTD PMID:18514395 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form] CTD PMID:25321483 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Per2 period circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of PER2 mRNA CTD PMID:19122877 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Per3 period circadian regulator 3 increases expression EXP selenomethylselenocysteine results in increased expression of PER3 mRNA CTD PMID:19122877 NCBI chr 5:168,088,126...168,123,482
Ensembl chr 5:168,086,998...168,123,395
JBrowse link
G Pgr progesterone receptor decreases expression
multiple interactions
ISO selenomethylselenocysteine results in decreased expression of PGR protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein
CTD PMID:18855134 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO selenomethylselenocysteine results in increased expression of PPP1R15A mRNA CTD PMID:10656618 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCE protein CTD PMID:10656618 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcz protein kinase C, zeta decreases expression ISO selenomethylselenocysteine results in decreased expression of PRKCZ protein CTD PMID:10656618 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB3B mRNA CTD PMID:18514395 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB4A mRNA CTD PMID:18514395 NCBI chr19:56,585,598...56,613,078
Ensembl chr19:56,585,767...56,613,075
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:21213327 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO selenomethylselenocysteine results in increased expression of SCARB1 mRNA CTD PMID:18514395 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selenof selenoprotein F increases expression ISO selenomethylselenocysteine results in increased expression of SELENOF mRNA CTD PMID:18514395 NCBI chr 2:250,600,823...250,633,903
Ensembl chr 2:250,600,823...250,633,897
JBrowse link
G Selenop selenoprotein P increases expression ISO selenomethylselenocysteine results in increased expression of SELENOP mRNA CTD PMID:18514395 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Selenow selenoprotein W increases expression ISO selenomethylselenocysteine results in increased expression of SELENOW mRNA CTD PMID:18514395 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 6:8,284,937...8,318,649
Ensembl chr 6:8,284,878...8,318,674
JBrowse link
G Slc6a19 solute carrier family 6 member 19 increases uptake ISO SLC6A19 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 1:32,199,869...32,218,628
Ensembl chr 1:32,199,810...32,220,045
JBrowse link
G Snap23 synaptosome associated protein 23 decreases expression ISO selenomethylselenocysteine results in decreased expression of SNAP23 mRNA CTD PMID:18514395 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Sort1 sortilin 1 increases expression ISO selenomethylselenocysteine results in increased expression of SORT1 mRNA CTD PMID:18514395 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 3:59,644,579...59,689,011
Ensembl chr 3:59,646,015...59,688,692
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions EXP [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein CTD PMID:19025659 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein CTD PMID:19360359 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 increases expression ISO selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA CTD PMID:18514395 NCBI chr 5:150,463,797...150,506,803
Ensembl chr 5:150,492,587...150,506,871
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
selenocystine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of GCLC mRNA] CTD PMID:22807314 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO selenocystine inhibits the reaction [Methylmercury Compounds results in decreased activity of MAPK1 protein] CTD PMID:23838314 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO selenocystine inhibits the reaction [Methylmercury Compounds results in decreased activity of MAPK3 protein] CTD PMID:23838314 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects localization
ISO NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of TXNRD1 mRNA]
selenocystine affects the localization of NFE2L2 protein
CTD PMID:22807314 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
affects expression
ISO NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of NQO1 mRNA]
selenocystine results in increased expression of NQO1 protein
selenocystine affects the expression of NQO1 mRNA
CTD PMID:22807314 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenocystine CTD PMID:18845132 NCBI chr 6:8,284,937...8,318,649
Ensembl chr 6:8,284,878...8,318,674
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases response to substance
increases expression
multiple interactions
ISO TXNRD1 protein results in decreased susceptibility to selenocystine
selenocystine results in increased expression of TXNRD1 mRNA; selenocystine results in increased expression of TXNRD1 protein
NFE2L2 mutant form inhibits the reaction [selenocystine results in increased expression of TXNRD1 mRNA]
CTD PMID:20920480, PMID:22807314 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions
decreases activity
ISO selenocystine inhibits the reaction [Zinc binds to XPA protein]
selenocystine results in decreased activity of XPA protein
CTD PMID:15265038 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
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selenomethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor affects expression ISO Selenomethionine affects the expression of ACD mRNA CTD PMID:17222674 NCBI chr19:37,665,289...37,668,043
Ensembl chr19:37,665,296...37,667,987
JBrowse link
G Aco2 aconitase 2 affects expression ISO Selenomethionine affects the expression of ACO2 mRNA CTD PMID:17222674 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
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G