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G |
PLCG1 |
phospholipase C gamma 1 |
decreases activity multiple interactions |
EXP |
1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein dipalmitoylphosphatidic acid inhibits the reaction [1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein] |
CTD |
PMID:2001791 |
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NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
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G |
PLCG1 |
phospholipase C gamma 1 |
increases activity |
EXP |
1-stearoyl-2-arachidonoylphosphatidic acid results in increased activity of PLCG1 protein |
CTD |
PMID:2001791 |
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NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
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G |
P2RY2 |
purinergic receptor P2Y2 |
multiple interactions |
EXP |
[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] |
CTD |
PMID:10604969 |
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NCBI chr21:24,987,568...25,009,754
Ensembl chr21:24,992,848...24,996,059
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G |
CDIPT |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
multiple interactions |
EXP |
[delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Hexachlorocyclohexane affects the activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate |
CTD |
PMID:2579070 |
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NCBI chr 6:17,910,141...17,914,573
Ensembl chr 6:17,910,192...17,914,653
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G |
ALPI |
alkaline phosphatase, intestinal |
increases chemical synthesis |
EXP |
ALPI protein results in increased chemical synthesis of nitrophenylphosphate |
CTD |
PMID:1495895 |
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NCBI chr25:44,107,418...44,110,947
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G |
P2RY2 |
purinergic receptor P2Y2 |
multiple interactions |
EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] |
CTD |
PMID:10604969 |
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NCBI chr21:24,987,568...25,009,754
Ensembl chr21:24,992,848...24,996,059
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G |
CFTR |
CF transmembrane conductance regulator |
multiple interactions |
EXP |
[1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein |
CTD |
PMID:15161604 |
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NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
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G |
CDIPT |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
multiple interactions |
EXP |
[delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Hexachlorocyclohexane affects the activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate |
CTD |
PMID:2579070 |
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NCBI chr 6:17,910,141...17,914,573
Ensembl chr 6:17,910,192...17,914,653
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G |
ACHE |
acetylcholinesterase |
decreases activity |
EXP |
Dichlorvos results in decreased activity of ACHE protein |
CTD |
PMID:89824 PMID:3627083 |
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NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Dichlorvos results in decreased activity of BCHE protein |
CTD |
PMID:3627083 PMID:4631366 |
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NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583
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G |
PLCG1 |
phospholipase C gamma 1 |
multiple interactions increases activity |
EXP |
dipalmitoylphosphatidic acid inhibits the reaction [1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein] dipalmitoylphosphatidic acid results in increased activity of PLCG1 protein |
CTD |
PMID:2001791 |
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NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Isoflurophate results in decreased activity of BCHE protein |
CTD |
PMID:4631366 |
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NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583
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G |
PLCG1 |
phospholipase C gamma 1 |
increases activity |
EXP |
dimyristoylphosphatidic acid results in increased activity of PLCG1 protein |
CTD |
PMID:2001791 |
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NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
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G |
PLCG1 |
phospholipase C gamma 1 |
increases activity |
EXP |
dioleoylphosphatidic acid results in increased activity of PLCG1 protein |
CTD |
PMID:2001791 |
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NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Paraoxon results in decreased activity of BCHE protein |
CTD |
PMID:4631366 |
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NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583
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G |
PIK3CG |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
multiple interactions |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; [Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; [Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate] |
CTD |
PMID:15958164 |
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NCBI chr18:13,576,966...13,611,748
Ensembl chr18:13,570,999...13,611,141
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G |
P2RY2 |
purinergic receptor P2Y2 |
multiple interactions increases activity |
EXP |
[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid; [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] |
CTD |
PMID:10604969 |
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NCBI chr21:24,987,568...25,009,754
Ensembl chr21:24,992,848...24,996,059
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G |
ACHE |
acetylcholinesterase |
multiple interactions decreases activity |
EXP |
[Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] |
CTD |
PMID:16915560 |
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NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
VX results in decreased activity of BCHE protein |
CTD |
PMID:16915560 |
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NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583
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