CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: aldrin
Accession: CHEBI:2564
browse the term
Definition: An organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with norbornadiene. A proinsecticide (by epoxidation of the non-chlorinated double bond to give dieldrin), it was widely used as an insecticide before being banned in the 1970s as a persistent organic pollutant.
Synonyms: exact_synonym: (1R,4S,4aS,5S,8R,8aR)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene
related_synonym: (1alpha,4alpha,4abeta,5alpha,8alpha,8abeta)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene; 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-endo-1,4-exo-5,8-dimethanonaphthalene; Compound 118; Formula=C12H8Cl6; HHDN; InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10+,11-; InChIKey=QBYJBZPUGVGKQQ-SJJAEHHWSA-N; SMILES=ClC1=C(Cl)[C@]2(Cl)[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3[C@@]1(Cl)C2(Cl)Cl; aldrine
xref: CAS:309-00-2; KEGG:C07552
xref_mesh: MESH:D000452
xref: PMID:18427830; PMID:21724225; PMID:26449612; PMID:28101603; PMID:28393264; PPDB:21; Patent:US2635977; Patent:US2911447; Pesticides:aldrin; Reaxys:2336652; Wikipedia:Aldrin
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Aadat
aminoadipate aminotransferase
increases expression
ISO
Aldrin results in increased expression of AADAT mRNA
CTD
PMID:18579281
NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540
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Abcd3
ATP binding cassette subfamily D member 3
increases expression
ISO
Aldrin results in increased expression of ABCD3 mRNA
CTD
PMID:18579281
NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:212,536,791...212,590,504
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Acap3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
decreases expression
ISO
Aldrin results in decreased expression of ACAP3 mRNA
CTD
PMID:18579281
NCBI chr 5:166,501,150...166,515,477
Ensembl chr 5:171,783,382...171,798,191
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Acbd5
acyl-CoA binding domain containing 5
increases expression
ISO
Aldrin results in increased expression of ACBD5 mRNA
CTD
PMID:18579281
NCBI chr17:85,206,178...85,248,909
Ensembl chr17:90,114,375...90,156,286
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Acer2
alkaline ceramidase 2
decreases expression
ISO
Aldrin results in decreased expression of ACER2 mRNA
CTD
PMID:18579281
NCBI chr 5:106,437,773...106,488,572
Ensembl chr 5:106,437,796...106,488,583
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Acly
ATP citrate lyase
increases expression
ISO
Aldrin results in increased expression of ACLY mRNA
CTD
PMID:18579281
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
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Acss2
acyl-CoA synthetase short-chain family member 2
increases expression
ISO
Aldrin results in increased expression of ACSS2 mRNA
CTD
PMID:18579281
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830
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Acvr1c
activin A receptor type 1C
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVR1C mRNA
CTD
PMID:19422813
NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:63,227,559...63,301,205
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Acvrl1
activin A receptor like type 1
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVRL1 mRNA
CTD
PMID:19422813
NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:134,118,024...134,135,305
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Adgrb2
adhesion G protein-coupled receptor B2
increases expression
ISO
Aldrin results in increased expression of ADGRB2 mRNA
CTD
PMID:18579281
NCBI chr 5:147,581,573...147,646,726
Ensembl chr 5:147,611,580...147,646,726
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
increases expression
ISO
Aldrin results in increased expression of ADH4 mRNA
CTD
PMID:18579281
NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
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Aif1l
allograft inflammatory factor 1-like
increases expression
ISO
Aldrin results in increased expression of AIF1L mRNA
CTD
PMID:18579281
NCBI chr 3:35,627,239...35,651,793
Ensembl chr 3:35,627,239...35,651,793
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Aifm2
AIF family member 2
decreases expression
ISO
Aldrin results in decreased expression of AIFM2 mRNA
CTD
PMID:18579281
NCBI chr20:29,654,283...29,679,239
Ensembl chr20:30,193,829...30,220,957
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Aldh18a1
aldehyde dehydrogenase 18 family, member A1
increases expression
ISO
Aldrin results in increased expression of ALDH18A1 mRNA
CTD
PMID:18579281
NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383
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Aldoc
aldolase, fructose-bisphosphate C
decreases expression
ISO
Aldrin results in decreased expression of ALDOA mRNA
CTD
PMID:18579281
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
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Alk
ALK receptor tyrosine kinase
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ALK mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721
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Alpi
alkaline phosphatase, intestinal
decreases expression
ISO
Aldrin results in decreased expression of ALPI mRNA
CTD
PMID:18579281
NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780
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Als2
alsin Rho guanine nucleotide exchange factor ALS2
increases expression
ISO
Aldrin results in increased expression of ALS2 mRNA
CTD
PMID:18579281
NCBI chr 9:68,107,310...68,180,192
Ensembl chr 9:68,107,528...68,179,660
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Ar
androgen receptor
multiple interactions affects binding
ISO EXP
Aldrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Aldrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] Aldrin binds to AR protein
CTD
PMID:14565775 PMID:21295777 PMID:26022396
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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Arsg
arylsulfatase G
increases expression
ISO
Aldrin results in increased expression of ARSG mRNA
CTD
PMID:18579281
NCBI chr10:94,912,094...95,063,021
Ensembl chr10:94,913,152...95,042,447
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Atl1
atlastin GTPase 1
increases expression
ISO
Aldrin results in increased expression of ATL1 mRNA
CTD
PMID:18579281
NCBI chr 6:94,113,149...94,210,955
Ensembl chr 6:94,112,877...94,211,219
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Bhlha15
basic helix-loop-helix family, member a15
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA
CTD
PMID:28263720
NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515
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Bsg
basigin
decreases expression
ISO
Aldrin results in decreased expression of BSG mRNA
CTD
PMID:18579281
NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
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Ca3
carbonic anhydrase 3
increases expression
ISO
Aldrin results in increased expression of CAR3 mRNA
CTD
PMID:18579281
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
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Cacna1f
calcium voltage-gated channel subunit alpha1 F
decreases expression
ISO
Aldrin results in decreased expression of CACNA1F mRNA
CTD
PMID:18579281
NCBI chr X:17,539,992...17,568,308
Ensembl chr X:17,539,920...17,568,308
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Camk1d
calcium/calmodulin-dependent protein kinase ID
increases expression
ISO
Aldrin results in increased expression of CAMK1D mRNA
CTD
PMID:18579281
NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012
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Casp14
caspase 14
increases expression
ISO
Aldrin results in increased expression of CASP14 mRNA
CTD
PMID:18579281
NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:11,580,339...11,583,171
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Ccn1
cellular communication network factor 1
increases expression
ISO
Aldrin results in increased expression of CCN1 mRNA
CTD
PMID:18579281
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
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Ccnb1
cyclin B1
increases expression
ISO
Aldrin results in increased expression of CCNB1 mRNA
CTD
PMID:18579281
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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Cd200
Cd200 molecule
increases expression
ISO
Aldrin results in increased expression of CD200 mRNA
CTD
PMID:18579281
NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569
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Cdh1
cadherin 1
increases expression
ISO
Aldrin results in increased expression of CDH1 mRNA
CTD
PMID:18579281
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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Cdh17
cadherin 17
increases expression
ISO
Aldrin results in increased expression of CDH17 mRNA
CTD
PMID:18579281
NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226
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Cdk14
cyclin-dependent kinase 14
increases expression
ISO
Aldrin results in increased expression of CDK14 mRNA
CTD
PMID:18579281
NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651
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Chrna4
cholinergic receptor nicotinic alpha 4 subunit
increases expression
ISO
Aldrin results in increased expression of CHRNA4 mRNA
CTD
PMID:18579281
NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105
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Cirbp
cold inducible RNA binding protein
increases expression
ISO
Aldrin results in increased expression of CIRBP mRNA
CTD
PMID:18579281
NCBI chr 7:9,533,857...9,538,899
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Cldn2
claudin 2
increases expression
ISO
Aldrin results in increased expression of CLDN2 mRNA
CTD
PMID:18579281
NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377
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Cnksr3
Cnksr family member 3
increases expression
ISO
Aldrin results in increased expression of CNKSR3 mRNA
CTD
PMID:18579281
NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:45,904,581...45,996,921
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Col15a1
collagen type XV alpha 1 chain
increases expression
ISO
Aldrin results in increased expression of COL15A1 mRNA
CTD
PMID:18579281
NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:66,297,461...66,403,170
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Col27a1
collagen type XXVII alpha 1 chain
increases expression
ISO
Aldrin results in increased expression of COL27A1 mRNA
CTD
PMID:18579281
NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:81,661,685...81,781,502
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Cox20
cytochrome c oxidase assembly factor COX20
increases expression
ISO
Aldrin results in increased expression of COX20 mRNA
CTD
PMID:18579281
NCBI chr13:90,065,900...90,075,386
Ensembl chr14:6,872,315...6,872,638
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Csrp2
cysteine and glycine-rich protein 2
decreases expression
ISO
Aldrin results in decreased expression of CSRP2 mRNA
CTD
PMID:18579281
NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:48,235,383...48,266,238
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases expression increases activity
ISO
Aldrin results in increased expression of CYP19A1 mRNA Aldrin results in increased activity of CYP19A1 protein
CTD
PMID:16996190
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
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Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
increases expression multiple interactions
ISO
Aldrin results in increased expression of CYP26A1 mRNA AGN 193109 inhibits the reaction [Aldrin results in increased expression of CYP26A1 mRNA]
CTD
PMID:15589975
NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression
ISO
Aldrin results in increased expression of CYP2B6 protein
CTD
PMID:15548381
NCBI chr 1:90,780,468...90,859,852
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Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
decreases expression
ISO
Aldrin results in decreased expression of CYP39A1 mRNA
CTD
PMID:18579281
NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:24,727,817...24,804,060
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
ISO
Aldrin results in increased expression of CYP3A4 protein
CTD
PMID:15548381
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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Cyp7b1
cytochrome P450 family 7 subfamily B member 1
increases expression
ISO
Aldrin results in increased expression of CYP7B1 mRNA
CTD
PMID:18579281
NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804
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Ddc
dopa decarboxylase
increases expression
ISO
Aldrin results in increased expression of DDC mRNA
CTD
PMID:18579281
NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
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Depdc7
DEP domain containing 7
increases expression
ISO
Aldrin results in increased expression of DEPDC7 mRNA
CTD
PMID:18579281
NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:111,554,706...111,575,979
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Dhx58
DEXH-box helicase 58
increases expression
ISO
Aldrin results in increased expression of DHX58 mRNA
CTD
PMID:18579281
NCBI chr10:85,620,352...85,631,776
Ensembl chr10:86,120,677...86,131,844
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Dkk3
dickkopf WNT signaling pathway inhibitor 3
decreases expression
ISO
Aldrin results in decreased expression of DKK3 mRNA
CTD
PMID:18579281
NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186
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Dmp1
dentin matrix acidic phosphoprotein 1
increases expression
ISO
Aldrin results in increased expression of DMP1 mRNA
CTD
PMID:18579281
NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,833,111...5,843,993
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Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
increases expression
ISO
Aldrin results in increased expression of EEPD1 mRNA
CTD
PMID:18579281
NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:32,233,070...32,340,147
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Epha3
Eph receptor A3
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA
CTD
PMID:28263720
NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425
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Epha8
Eph receptor A8
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA
CTD
PMID:28263720
NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:154,449,566...154,476,966
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Erbb3
erb-b2 receptor tyrosine kinase 3
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNA
CTD
PMID:19422813
NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120
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Eri3
ERI1 exoribonuclease family member 3
increases expression
ISO
Aldrin results in increased expression of ERI3 mRNA
CTD
PMID:18579281
NCBI chr 5:131,016,146...131,143,347
Ensembl chr 5:136,252,683...136,379,815
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Esr1
estrogen receptor 1
affects binding increases expression increases activity multiple interactions
ISO
Aldrin binds to ESR1 protein Aldrin results in increased expression of ESR1 mRNA Aldrin results in increased activity of ESR1 protein [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; Aldrin inhibits the reaction [Estradiol binds to ESR1 protein]
CTD
PMID:14579009 PMID:15064155 PMID:21295777 PMID:26022396
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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Esr2
estrogen receptor 2
multiple interactions
ISO
Aldrin binds to and results in decreased activity of ESR2 protein
CTD
PMID:16626760
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
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Ethe1
ETHE1, persulfide dioxygenase
increases expression
ISO
Aldrin results in increased expression of ETHE1 mRNA
CTD
PMID:18579281
NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998
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F7
coagulation factor VII
increases expression
ISO
Aldrin results in increased expression of F7 mRNA
CTD
PMID:18579281
NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738
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Fam133b
family with sequence similarity 133, member B
decreases expression
ISO
Aldrin results in decreased expression of FAM133B mRNA
CTD
PMID:18579281
NCBI chr 4:30,589,646...30,616,291
Ensembl chr 4:31,544,458...31,570,780
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Far1
fatty acyl CoA reductase 1
decreases expression
ISO
Aldrin results in decreased expression of FAR1 mRNA
CTD
PMID:18579281
NCBI chr 1:177,078,973...177,140,363
Ensembl chr 1:177,079,150...177,161,696
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Fbxo31
F-box protein 31
decreases expression
ISO
Aldrin results in decreased expression of FBXO31 mRNA
CTD
PMID:18579281
NCBI chr19:49,624,813...49,656,052
Ensembl chr19:66,533,437...66,564,674
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Fkbp5
FKBP prolyl isomerase 5
decreases expression
ISO
Aldrin results in decreased expression of FKBP5 mRNA
CTD
PMID:18579281
NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
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Fmo2
flavin containing dimethylaniline monoxygenase 2
decreases expression
ISO
Aldrin results in decreased expression of FMO2 mRNA
CTD
PMID:18579281
NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534
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Folr1
folate receptor alpha
increases expression
ISO
Aldrin results in increased expression of FOLR1 mRNA
CTD
PMID:18579281
NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669
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Foxc2
forkhead box C2
increases expression
ISO
Aldrin results in increased expression of FOXC2 mRNA
CTD
PMID:18579281
NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977
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Frmd4b
FERM domain containing 4B
increases expression
ISO
Aldrin results in increased expression of FRMD4B mRNA
CTD
PMID:18579281
NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:131,452,365...131,640,287
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Frs3
fibroblast growth factor receptor substrate 3
increases expression
ISO
Aldrin results in increased expression of FRS3 mRNA
CTD
PMID:18579281
NCBI chr 9:20,786,096...20,800,905
Ensembl chr 9:20,786,096...20,794,761
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Gbp6
guanylate binding protein family member 6
increases expression
ISO
Aldrin results in increased expression of GBP9 mRNA
CTD
PMID:18579281
NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,968,325...4,983,692 Ensembl chr14:4,968,325...4,983,692
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Gde1
glycerophosphodiester phosphodiesterase 1
decreases expression
ISO
Aldrin results in decreased expression of GDE1 mRNA
CTD
PMID:18579281
NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:182,451,184...182,466,772
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Gfra1
GDNF family receptor alpha 1
decreases expression multiple interactions
ISO
Aldrin results in decreased expression of GFRA1 mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA
CTD
PMID:18579281 PMID:28263720
NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501
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Gja4
gap junction protein, alpha 4
decreases expression
ISO
Aldrin results in decreased expression of GJA4 mRNA
CTD
PMID:18579281
NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216
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Gmppb
GDP-mannose pyrophosphorylase B
increases expression
ISO
Aldrin results in increased expression of GMPPB mRNA
CTD
PMID:18579281
NCBI chr 8:117,616,029...117,622,866
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Gnb5
G protein subunit beta 5
increases expression
ISO
Aldrin results in increased expression of GNB5 mRNA
CTD
PMID:18579281
NCBI chr 8:84,956,629...84,985,576
Ensembl chr 8:84,953,815...84,986,888
G
Got1
glutamic-oxaloacetic transaminase 1
decreases expression
ISO
Aldrin results in decreased expression of GOT1 mRNA
CTD
PMID:18579281
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
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Gpa33
glycoprotein A33
increases expression
ISO
Aldrin results in increased expression of GPA33 mRNA
CTD
PMID:18579281
NCBI chr13:78,381,141...78,414,765
Ensembl chr13:80,912,430...80,948,903
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Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
increases expression
ISO
Aldrin results in increased expression of GPAM mRNA
CTD
PMID:18579281
NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911
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Gpr12
G protein-coupled receptor 12
increases expression
ISO
Aldrin results in increased expression of GPR12 mRNA
CTD
PMID:18579281
NCBI chr12:8,522,709...8,525,875
Ensembl chr12:13,627,055...13,643,650
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Grb14
growth factor receptor bound protein 14
increases expression
ISO
Aldrin results in increased expression of GRB14 mRNA
CTD
PMID:18579281
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:69,976,339...70,091,921
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Gria3
glutamate ionotropic receptor AMPA type subunit 3
increases expression
ISO
Aldrin results in increased expression of GRIA3 mRNA
CTD
PMID:18579281
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679
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Hmox1
heme oxygenase 1
decreases expression
ISO
Aldrin results in decreased expression of HMOX1 mRNA
CTD
PMID:18579281
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hoxc8
homeobox C8
increases expression
ISO
Aldrin results in increased expression of HOXC8 mRNA
CTD
PMID:18579281
NCBI chr 7:134,127,937...134,130,503
Ensembl chr 7:136,006,162...136,009,849
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Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
increases expression
ISO
Aldrin results in increased expression of HSD17B2 mRNA
CTD
PMID:18579281
NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943
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Hspa8
heat shock protein family A (Hsp70) member 8
decreases expression
ISO
Aldrin results in decreased expression of HSPA8 mRNA
CTD
PMID:18579281
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
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Hspb1
heat shock protein family B (small) member 1
decreases expression
ISO
Aldrin results in decreased expression of HSPB1 mRNA
CTD
PMID:18579281
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
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Id1
inhibitor of DNA binding 1
decreases expression
ISO
Aldrin results in decreased expression of ID1 mRNA
CTD
PMID:18579281
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
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Ihh
Indian hedgehog signaling molecule
increases expression
ISO
Aldrin results in increased expression of IHH mRNA
CTD
PMID:18579281
NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203
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Ikbke
inhibitor of nuclear factor kappa B kinase subunit epsilon
increases expression
ISO
Aldrin results in increased expression of IKBKE mRNA
CTD
PMID:18579281
NCBI chr13:45,264,404...45,290,737
Ensembl chr13:45,264,412...45,289,396
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Il1r1
interleukin 1 receptor type 1
decreases expression
ISO
Aldrin results in decreased expression of IL1R1 mRNA
CTD
PMID:18579281
NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
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Il36a
interleukin 36, alpha
increases expression
ISO
Aldrin results in increased expression of IL36A mRNA
CTD
PMID:18579281
NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:27,395,146...27,399,695
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Insc
INSC, spindle orientation adaptor protein
increases expression
ISO
Aldrin results in increased expression of INSC mRNA
CTD
PMID:18579281
NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:178,427,423...178,535,047
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Ivns1abp
influenza virus NS1A binding protein
decreases expression
ISO
Aldrin results in decreased expression of IVNS1ABP mRNA
CTD
PMID:18579281
NCBI chr13:63,427,040...63,446,701
Ensembl chr13:65,977,045...65,997,547
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Kcnd2
potassium voltage-gated channel subfamily D member 2
increases expression
ISO
Aldrin results in increased expression of KCND2 mRNA
CTD
PMID:18579281
NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:50,742,839...51,243,522
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Kit
KIT proto-oncogene receptor tyrosine kinase
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
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Klhl31
kelch-like family member 31
increases expression
ISO
Aldrin results in increased expression of KLHL31 mRNA
CTD
PMID:18579281
NCBI chr 8:87,395,878...87,419,236
Ensembl chr 8:87,395,869...87,419,258
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Lama5
laminin subunit alpha 5
increases expression
ISO
Aldrin results in increased expression of LAMA5 mRNA
CTD
PMID:18579281
NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173
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Lgals9
galectin 9
increases expression
ISO
Aldrin results in increased expression of LGALS9 mRNA
CTD
PMID:18579281
NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070
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Limch1
LIM and calponin homology domains 1
decreases expression
ISO
Aldrin results in decreased expression of LIMCH1 mRNA
CTD
PMID:18579281
NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,466,433...41,778,837
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Lmo1
LIM domain only 1
increases expression
ISO
Aldrin results in increased expression of LMO1 mRNA
CTD
PMID:18579281
NCBI chr 1:172,567,156...172,603,282
Ensembl chr 1:172,567,156...172,603,157
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Lonp2
lon peptidase 2, peroxisomal
increases expression
ISO
Aldrin results in increased expression of LONP2 mRNA
CTD
PMID:18579281
NCBI chr19:20,407,475...20,498,985
Ensembl chr19:36,580,736...36,672,242
G
Lpar4
lysophosphatidic acid receptor 4
decreases expression
ISO
Aldrin results in decreased expression of LPAR4 mRNA
CTD
PMID:18579281
NCBI chr X:72,033,486...72,046,978
Ensembl chr X:76,106,071...76,119,808
G
Lpin1
lipin 1
decreases expression
ISO
Aldrin results in decreased expression of LPIN1 mRNA
CTD
PMID:18579281
NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991
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Lrrc2
leucine rich repeat containing 2
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA
CTD
PMID:28263720
NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:119,814,509...119,847,583
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Lrrc49
leucine rich repeat containing 49
decreases expression
ISO
Aldrin results in decreased expression of LRRC49 mRNA
CTD
PMID:18579281
NCBI chr 8:61,053,264...61,160,695
Ensembl chr 8:69,948,972...70,079,636
G
Lss
lanosterol synthase
increases expression
ISO
Aldrin results in increased expression of LSS mRNA
CTD
PMID:18579281
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,073,543...12,118,253
G
Mal2
mal, T-cell differentiation protein 2
increases expression
ISO
Aldrin results in increased expression of MAL2 mRNA
CTD
PMID:18579281
NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:87,790,239...87,850,403
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
decreases expression
ISO
Aldrin results in decreased expression of MAP1LC3B mRNA
CTD
PMID:18579281
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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Map4
microtubule-associated protein 4
increases expression
ISO
Aldrin results in increased expression of MAP4 mRNA
CTD
PMID:18579281
NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:118,804,022...118,942,805
G
Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
increases expression
ISO
Aldrin results in increased expression of MAPK8IP2 mRNA
CTD
PMID:18579281
NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:122,406,350...122,416,602
G
Mbnl2
muscleblind-like splicing regulator 2
decreases expression
ISO
Aldrin results in decreased expression of MBNL2 mRNA
CTD
PMID:18579281
NCBI chr15:97,385,278...97,542,924
Ensembl chr15:103,792,152...103,949,827
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Me1
malic enzyme 1
increases expression
ISO
Aldrin results in increased expression of ME1 mRNA
CTD
PMID:18579281
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
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Meis2
Meis homeobox 2
increases expression
ISO
Aldrin results in increased expression of MEIS2 mRNA
CTD
PMID:18579281
NCBI chr 3:123,197,066...123,399,002
Ensembl chr 3:123,197,066...123,397,751
G
Mertk
MER proto-oncogene, tyrosine kinase
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA
CTD
PMID:28263720
NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192
G
Mfsd13a
major facilitator superfamily domain containing 13A
increases expression
ISO
Aldrin results in increased expression of MFSD13A mRNA
CTD
PMID:18579281
NCBI chr 1:245,216,610...245,236,314
Ensembl chr 1:255,152,543...255,177,733
G
Mpdz
multiple PDZ domain crumbs cell polarity complex component
increases expression
ISO
Aldrin results in increased expression of MPDZ mRNA
CTD
PMID:18579281
NCBI chr 5:100,812,121...100,966,566
Ensembl chr 5:100,812,124...100,966,504
G
Mt1a
metallothionein 1A
decreases expression
ISO
Aldrin results in decreased expression of MT1 mRNA
CTD
PMID:18579281
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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Mt4
metallothionein 4
decreases expression
ISO
Aldrin results in decreased expression of MT4 mRNA
CTD
PMID:18579281
NCBI chr19:10,869,735...10,871,831
Ensembl chr19:10,869,735...10,871,831
G
Mtcl1
microtubule crosslinking factor 1
increases expression
ISO
Aldrin results in increased expression of MTCL1 mRNA
CTD
PMID:18579281
NCBI chr 9:113,722,138...113,888,413
Ensembl chr 9:113,753,000...113,888,098
G
Mvd
mevalonate diphosphate decarboxylase
increases expression
ISO
Aldrin results in increased expression of MVD mRNA
CTD
PMID:18579281
NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366
G
Mybph
myosin binding protein H
increases expression
ISO
Aldrin results in increased expression of MYBPH mRNA
CTD
PMID:18579281
NCBI chr13:45,653,156...45,660,893
Ensembl chr13:48,205,269...48,212,928
G
Ncf1
neutrophil cytosolic factor 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NCF1 mRNA]
CTD
PMID:28273962
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
G
Ndufb4
NADH:ubiquinone oxidoreductase subunit B4
decreases expression
ISO
Aldrin results in decreased expression of NDUFB4 mRNA
CTD
PMID:18579281
NCBI chr11:76,569,178...76,575,879
Ensembl chr11:76,569,178...76,575,879
G
Nefl
neurofilament light chain
increases expression
ISO
Aldrin results in increased expression of NEFL mRNA
CTD
PMID:18579281
NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515
G
Ngfr
nerve growth factor receptor
increases expression
ISO
Aldrin results in increased expression of NGFR mRNA
CTD
PMID:18579281
NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305
G
Nhsl1
NHS-like 1
increases expression
ISO
Aldrin results in increased expression of NHSL1 mRNA
CTD
PMID:18579281
NCBI chr 1:12,956,525...13,188,580
Ensembl chr 1:14,705,839...15,008,327
G
Niban2
niban apoptosis regulator 2
increases expression
ISO
Aldrin results in increased expression of NIBAN2 mRNA
CTD
PMID:18579281
NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:36,572,377...36,621,967
G
Nip7
nucleolar pre-rRNA processing protein NIP7
decreases expression
ISO
Aldrin results in decreased expression of NIP7 mRNA
CTD
PMID:18579281
NCBI chr19:51,872,306...51,874,448
Ensembl chr19:51,872,364...51,876,120
G
Nipal4
NIPA-like domain containing 4
increases expression
ISO
Aldrin results in increased expression of NIPAL4 mRNA
CTD
PMID:18579281
NCBI chr10:30,583,926...30,600,640
Ensembl chr10:31,085,267...31,101,979
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Nos3
nitric oxide synthase 3
increases expression multiple interactions
ISO
Aldrin results in increased expression of NOS3 mRNA Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NOS3 mRNA]
CTD
PMID:28273962
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions increases activity
ISO
Aldrin binds to and results in increased activity of NR1I2 protein Aldrin results in increased activity of NR1I2 protein
CTD
PMID:15548381 PMID:21115097
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases activity
ISO
Aldrin results in increased activity of NR1I3 protein
CTD
PMID:28927721
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
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Nrg4
neuregulin 4
decreases expression
ISO
Aldrin results in decreased expression of NRG4 mRNA
CTD
PMID:18579281
NCBI chr 8:55,586,253...55,677,829
Ensembl chr 8:64,488,722...64,573,439
G
Ntrk1
neurotrophic receptor tyrosine kinase 1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA
CTD
PMID:28263720
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA
CTD
PMID:28263720
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
G
Nts
neurotensin
increases expression
ISO
Aldrin results in increased expression of NTS mRNA
CTD
PMID:18579281
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
G
Nudt7
nudix hydrolase 7
increases expression
ISO
Aldrin results in increased expression of NUDT7 mRNA
CTD
PMID:18579281
NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994
G
Ogn
osteoglycin
decreases expression
ISO
Aldrin results in decreased expression of OGN mRNA
CTD
PMID:18579281
NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,238,500...15,259,252
G
Olfml2b
olfactomedin-like 2B
increases expression
ISO
Aldrin results in increased expression of OLFML2B mRNA
CTD
PMID:18579281
NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342
G
Or5b99
olfactory receptor family 5 subfamily B member 99
increases expression
ISO
Aldrin results in increased expression of OR5B99 mRNA
CTD
PMID:18579281
NCBI chr 1:210,136,841...210,137,767
Ensembl chr 1:219,561,418...219,562,344
G
Osr2
odd-skipped related transcription factor 2
increases expression
ISO
Aldrin results in increased expression of OSR2 mRNA
CTD
PMID:18579281
NCBI chr 7:68,372,500...68,380,195
Ensembl chr 7:68,373,049...68,380,805
G
Pcsk9
proprotein convertase subtilisin/kexin type 9
increases expression
ISO
Aldrin results in increased expression of PCSK9 mRNA
CTD
PMID:18579281
NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507
G
Pdgfra
platelet derived growth factor receptor alpha
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRA mRNA
CTD
PMID:19422813
NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516
G
Pdgfrb
platelet derived growth factor receptor beta
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
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Pfkp
phosphofructokinase, platelet
decreases expression
ISO
Aldrin results in decreased expression of PFKP mRNA
CTD
PMID:18579281
NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
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Pgr
progesterone receptor
multiple interactions affects binding
ISO
Aldrin inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; Aldrin inhibits the reaction [Progesterone binds to PGR protein] Aldrin binds to PGR protein
CTD
PMID:14579009 PMID:26022396
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
G
Pipox
pipecolic acid and sarcosine oxidase
increases expression
ISO
Aldrin results in increased expression of PIPOX mRNA
CTD
PMID:18579281
NCBI chr10:63,267,946...63,281,556
Ensembl chr10:63,267,972...63,282,273
G
Pkd1l2
polycystin 1 like 2
decreases expression
ISO
Aldrin results in decreased expression of PKD1L2 mRNA
CTD
PMID:18579281
NCBI chr19:61,958,351...62,045,324
Ensembl chr19:61,958,415...62,044,358
G
Plch2
phospholipase C, eta 2
increases expression
ISO
Aldrin results in increased expression of PLCH2 mRNA
CTD
PMID:18579281
NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:170,826,543...170,885,152
G
Plin4
perilipin 4
decreases expression
ISO
Aldrin results in decreased expression of PLIN4 mRNA
CTD
PMID:18579281
NCBI chr 9:1,016,334...1,025,249
Ensembl chr 9:1,016,302...1,025,368
G
Plk3
polo-like kinase 3
decreases expression
ISO
Aldrin results in decreased expression of PLK3 mRNA
CTD
PMID:18579281
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:135,843,725...135,848,900
G
Plxnd1
plexin D1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA
CTD
PMID:28263720
NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:150,675,377...150,715,566
G
Pnliprp2
pancreatic lipase related protein 2
increases expression
ISO
Aldrin results in increased expression of PNLIPRP2 mRNA
CTD
PMID:18579281
NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:267,883,906...267,902,572
G
Pnpla2
patatin-like phospholipase domain containing 2
decreases expression
ISO
Aldrin results in decreased expression of PNPLA2 mRNA
CTD
PMID:18579281
NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359
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Por
cytochrome p450 oxidoreductase
decreases expression
ISO
Aldrin results in decreased expression of POR mRNA
CTD
PMID:18579281
NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
G
Ppp1r10
protein phosphatase 1, regulatory subunit 10
decreases expression
ISO
Aldrin results in decreased expression of PPP1R10 mRNA
CTD
PMID:18579281
NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418
G
Ppp1r3g
protein phosphatase 1, regulatory subunit 3G
decreases expression
ISO
Aldrin results in decreased expression of PPP1R3G mRNA
CTD
PMID:18579281
NCBI chr17:29,080,407...29,083,739
Ensembl chr17:29,070,658...29,085,135
G
Prkd1
protein kinase D1
increases expression
ISO
Aldrin results in increased expression of PRKD1 mRNA
CTD
PMID:18579281
NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509
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Prok1
prokineticin 1
increases expression
ISO
Aldrin results in increased expression of PROK1 mRNA
CTD
PMID:18579281
NCBI chr 2:197,538,747...197,547,550
Ensembl chr 2:197,537,068...197,547,550
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Psat1
phosphoserine aminotransferase 1
increases expression
ISO
Aldrin results in increased expression of PSAT1 mRNA
CTD
PMID:18579281
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
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Psen2
presenilin 2
increases expression
ISO
Aldrin results in increased expression of PSEN2 mRNA
CTD
PMID:18579281
NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116
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Ptp4a1
protein tyrosine phosphatase 4A1
decreases expression
ISO
Aldrin results in decreased expression of PTP4A1 mRNA
CTD
PMID:18579281
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:40,710,250...40,718,176
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Ptprf
protein tyrosine phosphatase, receptor type, F
increases expression
ISO
Aldrin results in increased expression of PTPRF mRNA
CTD
PMID:18579281
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
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Qpct
glutaminyl-peptide cyclotransferase
increases expression
ISO
Aldrin results in increased expression of QPCT mRNA
CTD
PMID:18579281
NCBI chr 6:21,716,824...21,748,895
Ensembl chr 6:21,716,824...21,748,895
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Rarb
retinoic acid receptor, beta
increases expression
ISO
Aldrin results in increased expression of RARB mRNA
CTD
PMID:15589975
NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
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Rarg
retinoic acid receptor, gamma
increases expression
ISO
Aldrin results in increased expression of RARG mRNA
CTD
PMID:15589975
NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889
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Ret
ret proto-oncogene
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA
CTD
PMID:28263720
NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556
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Retreg1
reticulophagy regulator 1
decreases expression
ISO
Aldrin results in decreased expression of RETREG1 mRNA
CTD
PMID:18579281
NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:78,066,031...78,225,356
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Rpl39l1
ribosomal protein L39 like 1
increases expression
ISO
Aldrin results in increased expression of RPL39L mRNA
CTD
PMID:18579281
NCBI chr10:5,455,712...5,459,828
Ensembl chr10:5,962,515...5,966,621
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Rxrg
retinoid X receptor gamma
increases expression
ISO
Aldrin results in increased expression of RXRG mRNA
CTD
PMID:18579281
NCBI chr13:82,276,330...82,318,097
Ensembl chr13:82,276,291...82,318,095
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S100a10
S100 calcium binding protein A10
increases expression
ISO
Aldrin results in increased expression of S100A10 mRNA
CTD
PMID:18579281
NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103
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S100a9
S100 calcium binding protein A9
decreases expression
ISO
Aldrin results in decreased expression of S100A9 mRNA
CTD
PMID:18579281
NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870
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Sall2
spalt-like transcription factor 2
increases expression
ISO
Aldrin results in increased expression of SALL2 mRNA
CTD
PMID:18579281
NCBI chr15:25,021,345...25,038,918
Ensembl chr15:27,494,589...27,512,402
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Sc5d
sterol-C5-desaturase
increases expression
ISO
Aldrin results in increased expression of SC5D mRNA
CTD
PMID:18579281
NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277
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Scin
scinderin
increases expression
ISO
Aldrin results in increased expression of SCIN mRNA
CTD
PMID:18579281
NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:62,836,641...62,915,287
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Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
increases expression
ISO
Aldrin results in increased expression of SDR42E1 mRNA
CTD
PMID:18579281
NCBI chr19:45,715,366...45,727,901
Ensembl chr19:62,624,150...62,636,756
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Septin9
septin 9
increases expression
ISO
Aldrin results in increased expression of SEPTIN9 mRNA
CTD
PMID:18579281
NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,908,560...103,077,788
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Serpina12
serpin family A member 12
increases expression
ISO
Aldrin results in increased expression of SERPINA12 mRNA
CTD
PMID:18579281
NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:128,717,334...128,732,049
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Slc10a1
solute carrier family 10 member 1
increases expression
ISO
Aldrin results in increased expression of SLC10A1 mRNA
CTD
PMID:18579281
NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944
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Slc25a32
solute carrier family 25 member 32
decreases expression
ISO
Aldrin results in decreased expression of SLC25A32 mRNA
CTD
PMID:18579281
NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:72,007,975...72,045,647
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Slc36a2
solute carrier family 36 member 2
increases expression
ISO
Aldrin results in increased expression of SLC36A2 mRNA
CTD
PMID:18579281
NCBI chr10:39,778,667...39,806,781
Ensembl chr10:39,778,693...39,806,773
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Slc7a2
solute carrier family 7 member 2
decreases expression
ISO
Aldrin results in decreased expression of SLC7A2 mRNA
CTD
PMID:18579281
NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256
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Smim3
small integral membrane protein 3
increases expression
ISO
Aldrin results in increased expression of SMIM3 mRNA
CTD
PMID:18579281
NCBI chr18:56,200,458...56,252,778
Ensembl chr18:56,200,459...56,227,379
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Snx7
sorting nexin 7
increases expression
ISO
Aldrin results in increased expression of SNX7 mRNA
CTD
PMID:18579281
NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:208,528,049...208,613,075
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Sorbs3
sorbin and SH3 domain containing 3
decreases expression
ISO
Aldrin results in decreased expression of SORBS3 mRNA
CTD
PMID:18579281
NCBI chr15:45,252,921...45,284,758
Ensembl chr15:51,663,095...51,694,522
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Spint1
serine peptidase inhibitor, Kunitz type 1
decreases expression
ISO
Aldrin results in decreased expression of SPINT1 mRNA
CTD
PMID:18579281
NCBI chr 3:126,685,017...126,697,957
Ensembl chr 3:126,685,422...126,697,956
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Spon2
spondin 2
increases expression
ISO
Aldrin results in increased expression of SPON2 mRNA
CTD
PMID:18579281
NCBI chr14:81,713,070...81,742,510
Ensembl chr14:81,731,188...81,742,609
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Srebf1
sterol regulatory element binding transcription factor 1
increases expression
ISO
Aldrin results in increased expression of SREBF1 mRNA
CTD
PMID:18579281
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
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St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
decreases expression
ISO
Aldrin results in decreased expression of ST3GAL5 mRNA
CTD
PMID:18579281
NCBI chr 4:105,692,840...105,750,774
Ensembl chr 4:105,692,840...105,750,775
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Syt5
synaptotagmin 5
increases expression
ISO
Aldrin results in increased expression of SYT5 mRNA
CTD
PMID:18579281
NCBI chr 1:78,320,034...78,327,750
Ensembl chr 1:78,320,034...78,327,746
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Tacc2
transforming, acidic coiled-coil containing protein 2
decreases expression
ISO
Aldrin results in decreased expression of TACC2 mRNA
CTD
PMID:18579281
NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152
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Tcea2
transcription elongation factor A2
decreases expression
ISO
Aldrin results in decreased expression of TCEA2 mRNA
CTD
PMID:18579281
NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:189,165,603...189,182,540
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Tet2
tet methylcytosine dioxygenase 2
increases response to substance
ISO
TET2 gene SNP results in increased susceptibility to Aldrin
CTD
PMID:23593118
NCBI chr 2:224,662,654...224,746,819
Ensembl chr 2:224,662,654...224,746,186
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Tkfc
triokinase and FMN cyclase
increases expression
ISO
Aldrin results in increased expression of TKFC mRNA
CTD
PMID:18579281
NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:216,661,477...216,677,928
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Tom1l2
target of myb1 like 2 membrane trafficking protein
decreases expression
ISO
Aldrin results in decreased expression of TOM1L2 mRNA
CTD
PMID:18579281
NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,535,548...45,657,521
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Trak2
trafficking kinesin protein 2
decreases expression
ISO
Aldrin results in decreased expression of TRAK2 mRNA
CTD
PMID:18579281
NCBI chr 9:60,348,531...60,414,036
Ensembl chr 9:67,842,683...67,908,158
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Tril
TLR4 interactor with leucine-rich repeats
decreases expression
ISO
Aldrin results in decreased expression of TRIL mRNA
CTD
PMID:18579281
NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:84,239,028...84,260,209
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Tsc22d1
TSC22 domain family, member 1
increases expression
ISO
Aldrin results in increased expression of TSC22D1 mRNA
CTD
PMID:18579281
NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
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Ttc39c
tetratricopeptide repeat domain 39C
increases expression
ISO
Aldrin results in increased expression of TTC39C mRNA
CTD
PMID:18579281
NCBI chr18:4,043,364...4,162,660
Ensembl chr18:4,080,391...4,165,315
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Ugdh
UDP-glucose 6-dehydrogenase
increases expression
ISO
Aldrin results in increased expression of UGDH mRNA
CTD
PMID:18579281
NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
increases expression
ISO
Aldrin results in increased expression of UGT2B1 mRNA
CTD
PMID:18579281
NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
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Usp2
ubiquitin specific peptidase 2
decreases expression
ISO
Aldrin results in decreased expression of USP2 mRNA
CTD
PMID:18579281
NCBI chr 8:53,308,264...53,336,800
Ensembl chr 8:53,308,303...53,336,794
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Ust
uronyl-2-sulfotransferase
increases expression
ISO
Aldrin results in increased expression of UST mRNA
CTD
PMID:18579281
NCBI chr 1:4,487,316...4,782,579
Ensembl chr 1:4,489,925...4,782,356
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Vamp1
vesicle-associated membrane protein 1
decreases expression
ISO
Aldrin results in decreased expression of VAMP1 mRNA
CTD
PMID:18579281
NCBI chr 4:159,698,894...159,705,582
Ensembl chr 4:159,698,629...159,713,608
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Vangl2
VANGL planar cell polarity protein 2
increases expression
ISO
Aldrin results in increased expression of VANGL2 mRNA
CTD
PMID:18579281
NCBI chr13:86,995,124...87,021,770
Ensembl chr13:86,997,920...87,021,770
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Vcam1
vascular cell adhesion molecule 1
decreases expression
ISO
Aldrin results in decreased expression of VCAM1 mRNA
CTD
PMID:18579281
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
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Veph1
ventricular zone expressed PH domain-containing 1
increases expression
ISO
Aldrin results in increased expression of VEPH1 mRNA
CTD
PMID:18579281
NCBI chr 2:152,592,648...152,847,566
Ensembl chr 2:152,601,680...152,847,318
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Ypel1
yippee-like 1
increases expression
ISO
Aldrin results in increased expression of YPEL1 mRNA
CTD
PMID:18579281
NCBI chr11:83,921,799...83,936,409
G
Zhx3
zinc fingers and homeoboxes 3
decreases expression
ISO
Aldrin results in decreased expression of ZHX3 mRNA
CTD
PMID:18579281
NCBI chr 3:169,837,497...169,968,371
Ensembl chr 3:169,837,516...169,935,530
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Aadac
arylacetamide deacetylase
decreases expression
EXP
Dieldrin results in decreased expression of AADAC mRNA
CTD
PMID:23153324
NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
ISO
Dieldrin results in increased expression of ABCB1 mRNA
CTD
PMID:24464585
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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Abcc1
ATP binding cassette subfamily C member 1
increases expression
EXP
Dieldrin results in increased expression of ABCC1 mRNA
CTD
PMID:23153324
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
ISO
Dieldrin results in increased expression of ABCC2 mRNA
CTD
PMID:24464585
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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Abcg2
ATP binding cassette subfamily G member 2
increases expression
ISO
Dieldrin results in increased expression of ABCG2 mRNA
CTD
PMID:24464585
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
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Acly
ATP citrate lyase
affects expression
EXP
Dieldrin affects the expression of ACLY mRNA
CTD
PMID:22546817
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
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Acsm3
acyl-CoA synthetase medium-chain family member 3
decreases expression
EXP
Dieldrin results in decreased expression of ACSM3 mRNA
CTD
PMID:23153324
NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437
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Actn1
actinin, alpha 1
affects expression
EXP
Dieldrin affects the expression of ACTN1 mRNA
CTD
PMID:22546817
NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172
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Actn4
actinin alpha 4
affects methylation
ISO
Dieldrin affects the methylation of ACTN4 gene
CTD
PMID:38995845
NCBI chr 1:93,310,294...93,379,369
Ensembl chr 1:93,310,278...93,379,320
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Acvr1c
activin A receptor type 1C
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVR1C mRNA
CTD
PMID:19422813
NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:63,227,559...63,301,205
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Acvrl1
activin A receptor like type 1
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVRL1 mRNA
CTD
PMID:19422813
NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:134,118,024...134,135,305
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Adam15
ADAM metallopeptidase domain 15
decreases expression
ISO
Dieldrin results in decreased expression of ADAM15 mRNA
CTD
PMID:31068361
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:177,052,363...177,062,849
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Adam17
ADAM metallopeptidase domain 17
affects expression
EXP
Dieldrin affects the expression of ADAM17 mRNA
CTD
PMID:22546817
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344
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Adra2b
adrenoceptor alpha 2B
decreases expression
EXP
Dieldrin results in decreased expression of ADRA2B mRNA
CTD
PMID:18812211
NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:135,038,474...135,042,525
G
Adrb1
adrenoceptor beta 1
affects expression
EXP
Dieldrin affects the expression of ADRB1 mRNA
CTD
PMID:18812211
NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237
G
Adrb2
adrenoceptor beta 2
affects expression
EXP
Dieldrin affects the expression of ADRB2 mRNA
CTD
PMID:18812211
NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
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Aff3
ALF transcription elongation factor 3
affects methylation
ISO
Dieldrin affects the methylation of AFF3 gene
CTD
PMID:38995845
NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:47,894,903...48,353,000
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Ahr
aryl hydrocarbon receptor
increases activity
ISO EXP
Dieldrin results in increased activity of AHR protein
CTD
PMID:14636698
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Aifm2
AIF family member 2
affects expression
EXP
Dieldrin affects the expression of AIFM2 mRNA
CTD
PMID:22546817
NCBI chr20:29,654,283...29,679,239
Ensembl chr20:30,193,829...30,220,957
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Akt2
AKT serine/threonine kinase 2
affects expression
EXP
Dieldrin affects the expression of AKT2 mRNA
CTD
PMID:22546817
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
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Alk
ALK receptor tyrosine kinase
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ALK mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721
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Alox15
arachidonate 15-lipoxygenase
affects expression
EXP
Dieldrin affects the expression of ALOX15 mRNA
CTD
PMID:22546817
NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723
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Amigo2
adhesion molecule with Ig like domain 2
affects expression
EXP
Dieldrin affects the expression of AMIGO2 mRNA
CTD
PMID:22546817
NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218
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Ano1
anoctamin 1
affects methylation
ISO
Dieldrin affects the methylation of ANO1 gene
CTD
PMID:38995845
NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550
G
Anxa1
annexin A1
affects expression
EXP
Dieldrin affects the expression of ANXA1 mRNA
CTD
PMID:22546817
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
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Aox1
aldehyde oxidase 1
increases expression multiple interactions
ISO
Dieldrin results in increased expression of AOX1 mRNA NR1I3 protein affects the reaction [Dieldrin results in increased expression of AOX1 mRNA]
CTD
PMID:32435917
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
G
Apaf1
apoptotic peptidase activating factor 1
affects expression
EXP
Dieldrin affects the expression of APAF1 mRNA
CTD
PMID:22546817
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
G
Apbb1
amyloid beta precursor protein binding family B member 1
affects expression
EXP
Dieldrin affects the expression of APBB1 mRNA
CTD
PMID:22546817
NCBI chr 1:169,308,719...169,332,372
Ensembl chr 1:169,308,720...169,332,552
G
Apbb2
amyloid beta precursor protein binding family B member 2
affects expression
EXP
Dieldrin affects the expression of APBB2 mRNA
CTD
PMID:22546817
NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,911,785...42,232,280
G
Apbb3
amyloid beta precursor protein binding family B member 3
affects expression
EXP
Dieldrin affects the expression of APBB3 mRNA
CTD
PMID:22546817
NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,547,205...28,554,383
G
Apex2
apurinic/apyrimidinic endodeoxyribonuclease 2
affects expression
EXP
Dieldrin affects the expression of APEX2 mRNA
CTD
PMID:22546817
NCBI chr X:19,425,684...19,508,459
Ensembl chr X:22,914,944...22,936,011
G
Api5
apoptosis inhibitor 5
affects expression
EXP
Dieldrin affects the expression of API5 mRNA
CTD
PMID:22546817
NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:100,833,417...100,858,580
G
Aplp1
amyloid beta precursor like protein 1
affects expression
EXP
Dieldrin affects the expression of APLP1 mRNA
CTD
PMID:22546817
NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:94,824,072...94,834,610
G
Apoh
apolipoprotein H
affects methylation
ISO
Dieldrin affects the methylation of APOH gene
CTD
PMID:38995845
NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
G
App
amyloid beta precursor protein
affects expression
EXP
Dieldrin affects the expression of APP mRNA
CTD
PMID:22546817
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
G
Aqp11
aquaporin 11
decreases expression
EXP
Dieldrin results in decreased expression of AQP11 mRNA
CTD
PMID:23153324
NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:161,457,754...161,467,945
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Aqp9
aquaporin 9
decreases expression
EXP
Dieldrin results in decreased expression of AQP9 mRNA
CTD
PMID:23153324
NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240
G
Ar
androgen receptor
multiple interactions
ISO
Dieldrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Dieldrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dieldrin inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [Dieldrin results in increased activity of AR protein]
CTD
PMID:15064155 PMID:18324785 PMID:21295777 PMID:26022396
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
G
Araf
A-Raf proto-oncogene, serine/threonine kinase
affects expression
EXP
Dieldrin affects the expression of ARAF mRNA
CTD
PMID:22546817
NCBI chr X:1,227,392...1,292,356
Ensembl chr X:3,780,932...3,792,611
G
Arc
activity-regulated cytoskeleton-associated protein
increases expression
ISO
Dieldrin results in increased expression of ARC mRNA
CTD
PMID:31068361
NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220
G
Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor 6
affects expression
EXP
Dieldrin affects the expression of ARHGEF6 mRNA
CTD
PMID:22546817
NCBI chr X:135,145,447...135,264,636
Ensembl chr X:140,182,734...140,344,458
G
Arih2
ariadne RBR E3 ubiquitin protein ligase 2
decreases response to substance
ISO
ARIH2 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 8:118,175,267...118,234,425
Ensembl chr 8:118,175,267...118,234,284
G
Atf3
activating transcription factor 3
increases expression
ISO
Dieldrin results in increased expression of ATF3 mRNA
CTD
PMID:31068361
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
G
Atg10
autophagy related 10
increases response to substance
ISO
ATG10 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:23,844,482...24,133,368
G
Atg101
autophagy related 101
increases response to substance
ISO
ATG101 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 7:134,277,223...134,286,387
Ensembl chr 7:134,272,847...134,286,379
G
Atg4b
autophagy related 4B, cysteine peptidase
increases response to substance
ISO
ATG4B gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:101,729,772...101,761,456
Ensembl chr 9:101,726,782...101,761,622
G
Atg5
autophagy related 5
affects methylation
ISO
Dieldrin affects the methylation of ATG5 gene
CTD
PMID:38995845
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
G
Atg9a
autophagy related 9A
increases response to substance
ISO
ATG9A gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:84,126,071...84,136,666
G
Atm
ATM serine/threonine kinase
affects expression
EXP
Dieldrin affects the expression of ATM mRNA
CTD
PMID:22546817
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
G
Atp13a2
ATPase cation transporting 13A2
decreases expression
ISO
Dieldrin results in decreased expression of ATP13A2 mRNA
CTD
PMID:31068361
NCBI chr 5:158,575,727...158,595,157
Ensembl chr 5:158,575,749...158,595,156
G
Atp2a2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
decreases expression
EXP
Dieldrin results in decreased expression of ATP2A2 mRNA
CTD
PMID:23153324
NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934
G
Aurka
aurora kinase A
affects expression increases expression
EXP
Dieldrin affects the expression of AURKA mRNA Dieldrin results in increased expression of AURKA mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
G
Aurkb
aurora kinase B
affects expression
EXP
Dieldrin affects the expression of AURKB mRNA
CTD
PMID:22546817
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
G
Aven
apoptosis and caspase activation inhibitor
affects expression
EXP
Dieldrin affects the expression of AVEN mRNA
CTD
PMID:22546817
NCBI chr 3:119,753,395...119,886,009
Ensembl chr 3:119,872,661...119,886,008
G
Avpr1b
arginine vasopressin receptor 1B
increases expression
EXP
Dieldrin results in increased expression of AVPR1B mRNA
CTD
PMID:20682304
NCBI chr13:45,598,116...45,611,680
Ensembl chr13:45,598,763...45,611,277
G
Babam2
BRISC and BRCA1 A complex member 2
affects expression
EXP
Dieldrin affects the expression of BABAM2 mRNA
CTD
PMID:22546817
NCBI chr 6:30,089,065...30,467,508
Ensembl chr 6:30,071,611...30,467,341
G
Bag1
BAG cochaperone 1
affects expression
EXP
Dieldrin affects the expression of BAG1 mRNA
CTD
PMID:22546817
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:60,864,476...60,878,161
G
Bag3
BAG cochaperone 3
affects expression
EXP
Dieldrin affects the expression of BAG3 mRNA
CTD
PMID:22546817
NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
G
Bak1
BCL2-antagonist/killer 1
affects expression
EXP
Dieldrin affects the expression of BAK1 mRNA
CTD
PMID:22546817
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
G
Bax
BCL2 associated X, apoptosis regulator
affects expression
EXP
Dieldrin affects the expression of BAX mRNA
CTD
PMID:22546817
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
G
Bbc3
Bcl-2 binding component 3
affects expression
EXP
Dieldrin affects the expression of BBC3 mRNA
CTD
PMID:22546817
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
G
Bcat1
branched chain amino acid transaminase 1
increases expression
EXP
Dieldrin results in increased expression of BCAT1 mRNA
CTD
PMID:23153324
NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288
G
Bcl2
BCL2, apoptosis regulator
decreases response to substance multiple interactions
ISO
BCL2 protein results in decreased susceptibility to Dieldrin BCL2 protein inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Dieldrin results in increased activity of PRKCD protein]
CTD
PMID:15033812 PMID:15183012
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
G
Bcl2l1
Bcl2-like 1
affects expression
EXP
Dieldrin affects the expression of BCL2L1 mRNA
CTD
PMID:22546817
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
G
Bcl2l10
Bcl2-like 10
affects expression
EXP
Dieldrin affects the expression of BCL2L10 mRNA
CTD
PMID:22546817
NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:84,987,833...84,993,872
G
Bcl2l11
Bcl2-like 11
affects expression
EXP
Dieldrin affects the expression of BCL2L11 mRNA
CTD
PMID:22546817
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
G
Bcl2l13
Bcl2-like 13
affects expression
EXP
Dieldrin affects the expression of BCL2L13 mRNA
CTD
PMID:22546817
NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:155,728,284...155,781,158
G
Bcl2l14
Bcl2-like 14
affects expression
EXP
Dieldrin affects the expression of BCL2L14 mRNA
CTD
PMID:22546817
NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:168,948,946...168,990,079
G
Bcl3
BCL3, transcription coactivator
affects expression
EXP
Dieldrin affects the expression of BCL3 mRNA
CTD
PMID:22546817
NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368
G
Bcl6
BCL6, transcription repressor
affects expression
EXP
Dieldrin affects the expression of BCL6 mRNA
CTD
PMID:22546817
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
G
Bex3
brain expressed X-linked 3
increases expression affects expression
EXP
Dieldrin results in increased expression of BEX3 mRNA Dieldrin affects the expression of BEX3 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906
G
Bfar
bifunctional apoptosis regulator
affects expression
EXP
Dieldrin affects the expression of BFAR mRNA
CTD
PMID:22546817
NCBI chr10:1,552,019...1,585,040
Ensembl chr10:2,059,058...2,094,183
G
Bhlha15
basic helix-loop-helix family, member a15
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA
CTD
PMID:28263720
NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515
G
Bid
BH3 interacting domain death agonist
affects expression
EXP
Dieldrin affects the expression of BID mRNA
CTD
PMID:22546817
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
G
Bik
BCL2-interacting killer
affects expression
EXP
Dieldrin affects the expression of BIK mRNA
CTD
PMID:22546817
NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:116,552,303...116,571,317
G
Bin1
bridging integrator 1
affects expression
EXP
Dieldrin affects the expression of BIN1 mRNA
CTD
PMID:22546817
NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,283,801...24,341,458
G
Bin3
bridging integrator 3
affects expression
EXP
Dieldrin affects the expression of BIN3 mRNA
CTD
PMID:22546817
NCBI chr15:51,583,474...51,622,329
Ensembl chr15:51,583,481...51,622,329
G
Birc3
baculoviral IAP repeat-containing 3
affects expression
EXP
Dieldrin affects the expression of BIRC3 mRNA
CTD
PMID:22546817
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
G
Birc5
baculoviral IAP repeat-containing 5
affects expression
EXP
Dieldrin affects the expression of BIRC5 mRNA
CTD
PMID:22546817
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
G
Birc6
baculoviral IAP repeat-containing 6
increases response to substance
ISO
BIRC6 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:26,474,843...26,668,507
G
Bnip3
BCL2 interacting protein 3
affects expression
EXP
Dieldrin affects the expression of BNIP3 mRNA
CTD
PMID:22546817
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
G
Bnip3l
BCL2 interacting protein 3 like
affects expression
EXP
Dieldrin affects the expression of BNIP3L mRNA
CTD
PMID:22546817
NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282
G
Brca1
BRCA1, DNA repair associated
affects expression
EXP
Dieldrin affects the expression of BRCA1 mRNA
CTD
PMID:22546817
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
G
Brinp1
BMP/retinoic acid inducible neural specific 1
affects expression
EXP
Dieldrin affects the expression of BRINP1 mRNA
CTD
PMID:22546817
NCBI chr 5:87,363,621...87,565,580
Ensembl chr 5:87,364,050...87,508,256
G
Brinp2
BMP/retinoic acid inducible neural specific 2
affects expression
EXP
Dieldrin affects the expression of BRINP2 mRNA
CTD
PMID:22546817
NCBI chr13:72,964,498...73,065,312
Ensembl chr13:72,964,502...73,065,294
G
Btg1
BTG anti-proliferation factor 1
affects expression
EXP
Dieldrin affects the expression of BTG1 mRNA
CTD
PMID:22546817
NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:33,227,833...33,230,406
G
Btg2
BTG anti-proliferation factor 2
increases expression
ISO
Dieldrin results in increased expression of BTG2 mRNA
CTD
PMID:31068361
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
G
Btg3
BTG anti-proliferation factor 3
affects expression
EXP
Dieldrin affects the expression of BTG3 mRNA
CTD
PMID:22546817
NCBI chr11:17,030,156...17,046,069
Ensembl chr11:30,517,072...30,533,082
G
Bzw1
basic leucine zipper and W2 domains 1
affects expression
EXP
Dieldrin affects the expression of BZW1 mRNA
CTD
PMID:22546817
NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:67,424,866...67,439,684
G
Cables1
Cdk5 and Abl enzyme substrate 1
affects expression
EXP
Dieldrin affects the expression of CABLES1 mRNA
CTD
PMID:22546817
NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,351,652...3,455,956
G
Calm2
calmodulin 2
affects expression
EXP
Dieldrin affects the expression of CALM2 mRNA
CTD
PMID:22546817
NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657 Ensembl chr 6:64,519,554...64,520,657
G
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
affects expression
EXP
Dieldrin affects the expression of CAMK2A mRNA
CTD
PMID:22546817
NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504
G
Camk2b
calcium/calmodulin-dependent protein kinase II beta
affects expression affects methylation
EXP ISO
Dieldrin affects the expression of CAMK2B mRNA Dieldrin affects the methylation of CAMK2B gene
CTD
PMID:22546817 PMID:38995845
NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485
G
Camk2g
calcium/calmodulin-dependent protein kinase II gamma
affects expression
EXP
Dieldrin affects the expression of CAMK2G mRNA
CTD
PMID:22546817
NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310
G
Cand1
cullin-associated and neddylation-dissociated 1
affects expression
EXP
Dieldrin affects the expression of CAND1 mRNA
CTD
PMID:22546817
NCBI chr 7:54,681,114...54,719,002
Ensembl chr 7:56,551,394...56,604,655
G
Card9
caspase recruitment domain family, member 9
affects expression
EXP
Dieldrin affects the expression of CARD9 mRNA
CTD
PMID:22546817
NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:29,569,959...29,578,402
G
Casp12
caspase 12
affects expression
EXP
Dieldrin affects the expression of CASP12 mRNA
CTD
PMID:22546817
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:10,926,994...10,954,442
G
Casp3
caspase 3
decreases activity multiple interactions increases activity
EXP ISO
Dieldrin results in decreased activity of CASP3 protein [Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP3 protein; Dieldrin inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]; Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]; FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; rottlerin inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; SNCA protein promotes the reaction [Dieldrin results in increased expression of CASP3 protein] BCL2 protein inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]
CTD
PMID:10200566 PMID:12831855 PMID:15033812 PMID:15183012 PMID:15987830 PMID:20036686 PMID:21801747 PMID:22634143 More...
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
G
Casp4
caspase 4
affects expression
EXP
Dieldrin affects the expression of CASP4 mRNA
CTD
PMID:22546817
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:10,883,769...10,920,727
G
Casp7
caspase 7
multiple interactions affects expression
EXP
[Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP7 protein Dieldrin affects the expression of CASP7 mRNA
CTD
PMID:20036686 PMID:22546817
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
G
Casp8
caspase 8
affects expression
EXP
Dieldrin affects the expression of CASP8 mRNA
CTD
PMID:22546817
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
G
Casp8ap2
caspase 8 associated protein 2
affects expression
EXP
Dieldrin affects the expression of CASP8AP2 mRNA
CTD
PMID:22546817
NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
G
Casp9
caspase 9
increases activity
EXP
Dieldrin results in increased activity of CASP9 protein
CTD
PMID:12831855
Ensembl chr 5:159,391,188...159,409,648
G
Cbfa2t3
CBFA2/RUNX1 partner transcriptional co-repressor 3
affects methylation
ISO
Dieldrin affects the methylation of CBFA2T3 gene
CTD
PMID:38995845
NCBI chr19:50,679,897...50,750,028
Ensembl chr19:67,589,258...67,658,136
G
Cbl
Cbl proto-oncogene
decreases response to substance
ISO
CBL gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067
G
Cbx6
chromobox 6
decreases expression
ISO
Dieldrin results in decreased expression of CBX6 mRNA
CTD
PMID:31068361
NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:113,253,364...113,263,413
G
Cckbr
cholecystokinin B receptor
increases expression
EXP
Dieldrin results in increased expression of CCKBR mRNA
CTD
PMID:20682304
NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745
G
Ccnb1
cyclin B1
affects expression increases expression
EXP
Dieldrin affects the expression of CCNB1 mRNA Dieldrin results in increased expression of CCNB1 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
G
Ccnb2
cyclin B2
increases expression
EXP
Dieldrin results in increased expression of CCNB2 mRNA
CTD
PMID:23153324
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
G
Ccnd1
cyclin D1
affects expression
EXP
Dieldrin affects the expression of CCND1 mRNA
CTD
PMID:22546817
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
G
Ccne1
cyclin E1
affects expression
EXP
Dieldrin affects the expression of CCNE1 mRNA
CTD
PMID:22546817
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
G
Ccne2
cyclin E2
affects expression
EXP
Dieldrin affects the expression of CCNE2 mRNA
CTD
PMID:22546817
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
G
Ccnf
cyclin F
affects expression
EXP
Dieldrin affects the expression of CCNF mRNA
CTD
PMID:22546817
NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,758,421...13,783,837
G
Ccnh
cyclin H
affects expression
EXP
Dieldrin affects the expression of CCNH mRNA
CTD
PMID:22546817
NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860
G
Ccnj
cyclin J
affects expression
EXP
Dieldrin affects the expression of CCNJ mRNA
CTD
PMID:22546817
NCBI chr 1:239,659,588...239,677,367
Ensembl chr 1:249,608,969...249,626,794
G
Ccnt2
cyclin T2
affects expression
EXP
Dieldrin affects the expression of CCNT2 mRNA
CTD
PMID:22546817
NCBI chr13:41,804,007...41,845,641
Ensembl chr13:41,804,046...41,844,488
G
Ccpg1
cell cycle progression 1
affects expression
EXP
Dieldrin affects the expression of CCPG1 mRNA
CTD
PMID:22546817
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:82,600,536...82,660,246
G
Cd3g
CD3 gamma subunit of T-cell receptor complex
affects expression
EXP
Dieldrin affects the expression of CD3G mRNA
CTD
PMID:22546817
NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918
G
Cd69
Cd69 molecule
increases expression
ISO
Dieldrin results in increased expression of CD69 mRNA
CTD
PMID:31068361
NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509
G
Cdc20
cell division cycle 20
affects expression
EXP
Dieldrin affects the expression of CDC20 mRNA
CTD
PMID:22546817
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:137,251,596...137,255,799
G
Cdc23
cell division cycle 23
affects expression
EXP
Dieldrin affects the expression of CDC23 mRNA
CTD
PMID:22546817
NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,510,355...26,532,646
G
Cdc25b
cell division cycle 25B
affects expression
EXP
Dieldrin affects the expression of CDC25B mRNA
CTD
PMID:22546817
NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:138,860,130...138,870,492
G
Cdc25c
cell division cycle 25C
affects expression
EXP
Dieldrin affects the expression of CDC25C mRNA
CTD
PMID:22546817
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
G
Cdc26
cell division cycle 26
affects expression
EXP
Dieldrin affects the expression of CDC26 mRNA
CTD
PMID:22546817
NCBI chr 5:75,844,852...75,859,830
Ensembl chr 5:80,861,659...80,875,326
G
Cdc34
cell division cycle 34, ubiquitin conjugating enzyme
affects expression
EXP
Dieldrin affects the expression of CDC34 mRNA
CTD
PMID:22546817
NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,668,210...10,674,526
G
Cdc37l1
cell division cycle 37-like 1
affects expression
EXP
Dieldrin affects the expression of CDC37L1 mRNA
CTD
PMID:22546817
NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:236,118,555...236,207,079
G
Cdc6
cell division cycle 6
affects expression
EXP
Dieldrin affects the expression of CDC6 mRNA
CTD
PMID:22546817
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:84,360,381...84,374,241
G
Cdc7
cell division cycle 7
affects expression
EXP
Dieldrin affects the expression of CDC7 mRNA
CTD
PMID:22546817
NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,949,539...2,969,656
G
Cdca2
cell division cycle associated 2
affects expression
EXP
Dieldrin affects the expression of CDCA2 mRNA
CTD
PMID:22546817
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:46,071,360...46,116,639
G
Cdca3
cell division cycle associated 3
affects expression
EXP
Dieldrin affects the expression of CDCA3 mRNA
CTD
PMID:22546817
NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:159,321,014...159,325,068
G
Cdca4
cell division cycle associated 4
affects expression
EXP
Dieldrin affects the expression of CDCA4 mRNA
CTD
PMID:22546817
NCBI chr 6:131,892,305...131,901,571
Ensembl chr 6:137,713,051...137,722,580
G
Cdca8
cell division cycle associated 8
increases expression
EXP
Dieldrin results in increased expression of CDCA8 mRNA
CTD
PMID:23153324
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:142,461,084...142,483,283
G
Cdh13
cadherin 13
affects methylation
ISO
Dieldrin affects the methylation of CDH13 gene
CTD
PMID:38995845
NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119
G
Cdh2
cadherin 2
decreases expression
EXP
Dieldrin results in decreased expression of CDH2 protein
CTD
PMID:15082077
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
G
Cdk1
cyclin-dependent kinase 1
affects expression
EXP
Dieldrin affects the expression of CDK1 mRNA
CTD
PMID:22546817
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
G
Cdk11b
cyclin-dependent kinase 11B
affects expression
EXP
Dieldrin affects the expression of CDK11B mRNA
CTD
PMID:22546817
NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:171,495,776...171,521,145
G
Cdk13
cyclin-dependent kinase 13
affects expression
EXP
Dieldrin affects the expression of CDK13 mRNA
CTD
PMID:22546817
NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257
G
Cdk2
cyclin dependent kinase 2
affects expression
EXP
Dieldrin affects the expression of CDK2 mRNA
CTD
PMID:22546817
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
G
Cdk6
cyclin-dependent kinase 6
affects expression
EXP
Dieldrin affects the expression of CDK6 mRNA
CTD
PMID:22546817
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
affects expression
EXP
Dieldrin affects the expression of CDKN1A mRNA
CTD
PMID:22546817
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
G
Cdkn1c
cyclin-dependent kinase inhibitor 1C
affects expression
EXP
Dieldrin affects the expression of CDKN1C mRNA
CTD
PMID:22546817
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
G
Cdkn3
cyclin-dependent kinase inhibitor 3
affects expression increases expression
EXP
Dieldrin affects the expression of CDKN3 mRNA Dieldrin results in increased expression of CDKN3 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:22,502,382...22,513,722
G
Cebpb
CCAAT/enhancer binding protein beta
affects expression
EXP
Dieldrin affects the expression of CEBPB mRNA
CTD
PMID:22546817
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
G
Cenpe
centromere protein E
increases expression
EXP
Dieldrin results in increased expression of CENPE mRNA
CTD
PMID:23153324
NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
G
Cenpf
centromere protein F
affects expression
EXP
Dieldrin affects the expression of CENPF mRNA
CTD
PMID:22546817
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
G
Cfdp1
craniofacial development protein 1
affects expression
EXP
Dieldrin affects the expression of CFDP1 mRNA
CTD
PMID:22546817
NCBI chr19:56,627,596...56,733,099
Ensembl chr19:56,626,963...56,733,098
G
Cgn
cingulin
decreases expression
EXP
Dieldrin results in decreased expression of CGN mRNA
CTD
PMID:23153324
NCBI chr 2:184,997,425...185,024,785
Ensembl chr 2:184,997,425...185,023,635
G
Cgrrf1
cell growth regulator with ring finger domain 1
affects expression
EXP
Dieldrin affects the expression of CGRRF1 mRNA
CTD
PMID:22546817
NCBI chr15:20,088,564...20,109,042
Ensembl chr15:22,568,332...22,588,811
G
Chd7
chromodomain helicase DNA binding protein 7
affects methylation
ISO
Dieldrin affects the methylation of CHD7 gene
CTD
PMID:38995845
NCBI chr 5:26,609,245...26,792,736
Ensembl chr 5:26,609,407...26,792,734
G
Chek2
checkpoint kinase 2
affects expression
EXP
Dieldrin affects the expression of CHEK2 mRNA
CTD
PMID:22546817
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
G
Chgb
chromogranin B
decreases expression
EXP
Dieldrin results in decreased expression of CHGB mRNA
CTD
PMID:18812211
NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054
G
Chrm1
cholinergic receptor, muscarinic 1
decreases expression
EXP
Dieldrin results in decreased expression of CHRM1 mRNA
CTD
PMID:18812211
NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:214,995,872...215,020,602
G
Chrm2
cholinergic receptor, muscarinic 2
affects expression
EXP
Dieldrin affects the expression of CHRM2 mRNA
CTD
PMID:18812211
NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464
G
Chrm4
cholinergic receptor, muscarinic 4
affects expression
EXP
Dieldrin affects the expression of CHRM4 mRNA
CTD
PMID:18812211
NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771
G
Chrm5
cholinergic receptor, muscarinic 5
increases expression
EXP
Dieldrin results in increased expression of CHRM5 mRNA
CTD
PMID:18812211
NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:119,735,975...119,792,166
G
Chrna1
cholinergic receptor nicotinic alpha 1 subunit
decreases expression
EXP
Dieldrin results in decreased expression of CHRNA1 mRNA
CTD
PMID:23153324
NCBI chr 3:78,862,286...78,877,353
Ensembl chr 3:78,862,286...78,877,353
G
Chrna10
cholinergic receptor nicotinic alpha 10 subunit
affects methylation
ISO
Dieldrin affects the methylation of CHRNA10 gene
CTD
PMID:38995845
NCBI chr 1:165,898,932...165,905,348
Ensembl chr 1:165,899,261...165,903,458
G
Chrna2
cholinergic receptor nicotinic alpha 2 subunit
decreases expression
EXP
Dieldrin results in decreased expression of CHRNA2 mRNA
CTD
PMID:18812211
NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144
G
Chrna3
cholinergic receptor nicotinic alpha 3 subunit
decreases expression
EXP
Dieldrin results in decreased expression of CHRNA3 mRNA
CTD
PMID:18812211
NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:64,297,755...64,311,412
G
Chrna4
cholinergic receptor nicotinic alpha 4 subunit
affects expression
EXP
Dieldrin affects the expression of CHRNA4 mRNA
CTD
PMID:18812211
NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105
G
Chrna5
cholinergic receptor nicotinic alpha 5 subunit
decreases expression
EXP
Dieldrin results in decreased expression of CHRNA5 mRNA
CTD
PMID:18812211
NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:64,265,879...64,294,233
G
Chrna7
cholinergic receptor nicotinic alpha 7 subunit
increases expression
EXP
Dieldrin results in increased expression of CHRNA7 mRNA
CTD
PMID:18812211
NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858
G
Chrnb4
cholinergic receptor nicotinic beta 4 subunit
decreases expression
EXP
Dieldrin results in decreased expression of CHRNB4 mRNA
CTD
PMID:18812211
NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:64,313,669...64,333,248
G
Cidea
cell death-inducing DFFA-like effector a
affects expression
EXP
Dieldrin affects the expression of CIDEA mRNA
CTD
PMID:22546817
NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382
G
Cit
citron rho-interacting serine/threonine kinase
affects expression
EXP
Dieldrin affects the expression of CIT mRNA
CTD
PMID:22546817
NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656
G
Cldn2
claudin 2
decreases expression
EXP
Dieldrin results in decreased expression of CLDN2 mRNA
CTD
PMID:23153324
NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377
G
Clk1
CDC-like kinase 1
affects expression
EXP
Dieldrin affects the expression of CLK1 mRNA
CTD
PMID:22546817
NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:67,441,952...67,451,187
G
Col18a1
collagen type XVIII alpha 1 chain
affects expression
EXP
Dieldrin affects the expression of COL18A1 mRNA
CTD
PMID:22546817
NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112
G
Comt
catechol-O-methyltransferase
increases expression
EXP
Dieldrin results in increased expression of COMT mRNA
CTD
PMID:18812211
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
G
Cort
cortistatin
affects expression
EXP
Dieldrin affects the expression of CORT mRNA
CTD
PMID:22546817
NCBI chr 5:159,560,591...159,562,032
G
Creb1
cAMP responsive element binding protein 1
increases phosphorylation
ISO
Dieldrin results in increased phosphorylation of CREB1 protein
CTD
PMID:31068361
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
G
Crh
corticotropin releasing hormone
increases expression
EXP
Dieldrin results in increased expression of CRH mRNA
CTD
PMID:20682304
NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
G
Crk
CRK proto-oncogene, adaptor protein
affects expression
EXP
Dieldrin affects the expression of CRK mRNA
CTD
PMID:22546817
NCBI chr10:61,028,736...61,054,971
Ensembl chr10:61,028,757...61,082,988
G
Cse1l
chromosome segregation 1 like
affects expression
EXP
Dieldrin affects the expression of CSE1L mRNA
CTD
PMID:22546817
NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:176,060,215...176,108,734
G
Csnk1d
casein kinase 1, delta
affects expression
EXP
Dieldrin affects the expression of CSNK1D mRNA
CTD
PMID:22546817
NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953
G
Csnk2a1
casein kinase 2 alpha 1
decreases response to substance
ISO
CSNK2A1 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698
G
Csrnp1
cysteine and serine rich nuclear protein 1
increases expression
ISO
Dieldrin results in increased expression of CSRNP1 mRNA
CTD
PMID:31068361
NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:128,582,365...128,588,469
G
Cstb
cystatin B
affects expression
EXP
Dieldrin affects the expression of CSTB mRNA
CTD
PMID:22546817
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,158...10,247,199
G
Ctcf
CCCTC-binding factor
affects expression
EXP
Dieldrin affects the expression of CTCF mRNA
CTD
PMID:22546817
NCBI chr19:50,431,478...50,481,013
Ensembl chr19:50,431,689...50,481,012
G
Cul1
cullin 1
affects expression
EXP
Dieldrin affects the expression of CUL1 mRNA
CTD
PMID:22546817
NCBI chr 4:77,551,781...77,634,210
Ensembl chr 4:77,551,787...77,621,760
G
Cul2
cullin 2
affects expression
EXP
Dieldrin affects the expression of CUL2 mRNA
CTD
PMID:22546817
NCBI chr17:54,169,093...54,210,197
Ensembl chr17:58,864,274...58,905,132
G
Cul5
cullin 5
affects expression
EXP
Dieldrin affects the expression of CUL5 mRNA
CTD
PMID:22546817
NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463
G
Cul7
cullin 7
affects methylation
ISO
Dieldrin affects the methylation of CUL7 gene
CTD
PMID:38995845
NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:21,816,703...21,830,344
G
Cwf19l1
CWF19 like cell cycle control factor 1
affects expression
EXP
Dieldrin affects the expression of CWF19L1 mRNA
CTD
PMID:22546817
NCBI chr 1:242,997,720...243,020,989
Ensembl chr 1:252,946,934...252,970,168
G
Cwf19l2
CWF19 like cell cycle control factor 2
affects expression
EXP
Dieldrin affects the expression of CWF19L2 mRNA
CTD
PMID:22546817
NCBI chr 6:290,148...356,636
Ensembl chr 6:6,026,861...6,102,635
G
Cycs
cytochrome c, somatic
multiple interactions affects localization
EXP
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Dieldrin affects the localization of CYCS protein]
CTD
PMID:12831855
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
Dieldrin results in increased expression of CYP1A1 mRNA
CTD
PMID:10910964
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
Dieldrin results in increased expression of CYP1A2 mRNA
CTD
PMID:10910964
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
increases expression
EXP
Dieldrin results in increased expression of CYP1B1 mRNA
CTD
PMID:10910964
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
G
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
multiple interactions increases expression
ISO
AGN 193109 inhibits the reaction [Dieldrin results in increased expression of CYP26A1 mRNA]
CTD
PMID:15589975
NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression multiple interactions
ISO
Dieldrin results in increased expression of CYP2B6 protein NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP2B10 mRNA]
CTD
PMID:12049174 PMID:15548381 PMID:32435917
NCBI chr 1:90,780,468...90,859,852
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression multiple interactions
ISO
Dieldrin results in increased expression of CYP3A4 protein [DDT co-treated with Dieldrin] results in increased expression of CYP3A4 mRNA; Dieldrin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]
CTD
PMID:12417264 PMID:15548381 PMID:25028461
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
G
Cyp4f39
cytochrome P450, family 4, subfamily f, polypeptide 39
affects methylation
ISO
Dieldrin affects the methylation of CYP4F39 gene
CTD
PMID:38995845
NCBI chr 7:12,082,821...12,156,076
Ensembl chr 7:12,083,888...12,156,076
G
Cyp8b1
cytochrome P450 family 8 subfamily B member 1
decreases expression
EXP
Dieldrin results in decreased expression of CYP8B1 mRNA
CTD
PMID:23153324
NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689
G
Dad1
defender against cell death 1
affects expression
EXP
Dieldrin affects the expression of DAD1 mRNA
CTD
PMID:22546817
NCBI chr15:27,677,286...27,697,120
Ensembl chr15:31,647,326...31,667,287
G
Dap
death-associated protein
affects expression
EXP
Dieldrin affects the expression of DAP mRNA
CTD
PMID:22546817
NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:83,910,060...83,962,673
G
Dap3
death associated protein 3
affects expression
EXP
Dieldrin affects the expression of DAP3 mRNA
CTD
PMID:22546817
NCBI chr 2:176,617,151...176,645,293
Ensembl chr 2:176,617,155...176,644,270
G
Daxx
death-domain associated protein
affects expression
EXP
Dieldrin affects the expression of DAXX mRNA
CTD
PMID:22546817
NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720
G
Dbh
dopamine beta-hydroxylase
decreases expression
EXP
Dieldrin results in decreased expression of DBH mRNA
CTD
PMID:18812211
NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316
G
Dclk2
doublecortin-like kinase 2
affects methylation
ISO
Dieldrin affects the methylation of DCLK2 gene
CTD
PMID:38995845
NCBI chr 2:174,506,660...174,636,353
Ensembl chr 2:174,506,660...174,636,192
G
Ddit3
DNA-damage inducible transcript 3
affects expression increases expression
EXP ISO
Dieldrin affects the expression of DDIT3 mRNA Dieldrin results in increased expression of DDIT3 mRNA
CTD
PMID:22546817 PMID:28844784 PMID:31068361
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
G
Ddit4
DNA-damage-inducible transcript 4
affects expression
EXP
Dieldrin affects the expression of DDIT4 mRNA
CTD
PMID:22546817
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
G
Dedd
death effector domain-containing
affects expression
EXP
Dieldrin affects the expression of DEDD mRNA
CTD
PMID:22546817
NCBI chr13:83,755,874...83,769,982
Ensembl chr13:86,288,350...86,302,446
G
Depdc5
DEP domain containing 5, GATOR1 subcomplex subunit
increases response to substance
ISO
DEPDC5 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr14:81,956,777...82,087,392
Ensembl chr14:81,956,777...82,087,246
G
Dgat2
diacylglycerol O-acyltransferase 2
decreases expression
ISO
Dieldrin results in decreased expression of DGAT2 mRNA
CTD
PMID:31068361
NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
G
Dhx16
DEAH-box helicase 16
affects expression
EXP
Dieldrin affects the expression of DHX16 mRNA
CTD
PMID:22546817
NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,866,804...2,879,751
G
Diablo
diablo, IAP-binding mitochondrial protein
affects expression
EXP
Dieldrin affects the expression of DIABLO mRNA
CTD
PMID:22546817
NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
G
Dlg2
discs large MAGUK scaffold protein 2
affects methylation
ISO
Dieldrin affects the methylation of DLG2 gene
CTD
PMID:38995845
NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215
G
Dlg5
discs large MAGUK scaffold protein 5
affects expression
EXP
Dieldrin affects the expression of DLG5 mRNA
CTD
PMID:22546817
NCBI chr15:125,287...237,334
Ensembl chr15:125,290...237,332
G
Dlgap1
DLG associated protein 1
affects methylation
ISO
Dieldrin affects the methylation of DLGAP1 gene
CTD
PMID:38995845
NCBI chr 9:117,304,144...118,173,463
Ensembl chr 9:117,614,061...118,173,463
G
Dlgap5
DLG associated protein 5
affects expression
EXP
Dieldrin affects the expression of DLGAP5 mRNA
CTD
PMID:22546817
NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176
G
Dmtn
dematin actin binding protein
affects methylation
ISO
Dieldrin affects the methylation of DMTN gene
CTD
PMID:38995845
NCBI chr15:45,677,974...45,702,261
Ensembl chr15:52,087,667...52,112,128
G
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
increases expression
ISO
Dieldrin results in increased expression of DNAJB1 mRNA
CTD
PMID:31068361
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
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Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
affects expression
EXP
Dieldrin affects the expression of DNAJB9 mRNA
CTD
PMID:22546817
NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
G
Dnase1l3
deoxyribonuclease 1L3
affects expression
EXP
Dieldrin affects the expression of DNASE1L3 mRNA
CTD
PMID:22546817
NCBI chr15:19,351,683...19,378,536
Ensembl chr15:19,352,493...19,378,531
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Dnase2
deoxyribonuclease 2, lysosomal
affects expression
EXP
Dieldrin affects the expression of DNASE2 mRNA
CTD
PMID:22546817
NCBI chr19:40,149,505...40,152,225
Ensembl chr19:40,149,505...40,152,225
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Dnmt3a
DNA methyltransferase 3 alpha
affects methylation
ISO
Dieldrin affects the methylation of DNMT3A gene
CTD
PMID:38995845
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
G
Drd3
dopamine receptor D3
increases expression
EXP
Dieldrin results in increased expression of DRD3 mRNA
CTD
PMID:18812211
NCBI chr11:70,385,586...70,437,793
Ensembl chr11:70,385,586...70,446,760
G
Drd4
dopamine receptor D4
decreases expression
EXP
Dieldrin results in decreased expression of DRD4 mRNA
CTD
PMID:18812211
NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:205,826,049...205,830,458
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Dst
dystonin
affects expression
EXP
Dieldrin affects the expression of DST mRNA
CTD
PMID:22546817
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
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Dtymk
deoxythymidylate kinase
affects expression
EXP
Dieldrin affects the expression of DTYMK mRNA
CTD
PMID:22546817
NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504
G
Dusp1
dual specificity phosphatase 1
affects expression increases expression
EXP ISO
Dieldrin affects the expression of DUSP1 mRNA Dieldrin results in increased expression of DUSP1 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
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Dusp2
dual specificity phosphatase 2
increases expression
ISO
Dieldrin results in increased expression of DUSP2 mRNA
CTD
PMID:31068361
NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:135,009,590...135,011,809
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Dusp22
dual specificity phosphatase 22
affects expression
EXP
Dieldrin affects the expression of DUSP22 mRNA
CTD
PMID:22546817
NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895
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E2f1
E2F transcription factor 1
affects expression increases expression
EXP
Dieldrin affects the expression of E2F1 mRNA Dieldrin results in increased expression of E2F1 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
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E2f5
E2F transcription factor 5
affects expression
EXP
Dieldrin affects the expression of E2F5 mRNA
CTD
PMID:22546817
NCBI chr 2:88,718,567...88,734,143
Ensembl chr 2:88,718,567...88,734,143
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E2f8
E2F transcription factor 8
increases expression
EXP
Dieldrin results in increased expression of E2F8 mRNA
CTD
PMID:23153324
NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:107,701,985...107,720,009
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Ebag9
estrogen receptor binding site associated antigen 9
affects expression
EXP
Dieldrin affects the expression of EBAG9 mRNA
CTD
PMID:22546817
NCBI chr 7:77,695,213...77,713,565
Ensembl chr 7:77,695,072...77,713,557
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Ect2
epithelial cell transforming 2
increases expression
EXP
Dieldrin results in increased expression of ECT2 mRNA
CTD
PMID:23153324
NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626
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Eef1akmt3
EEF1A lysine methyltransferase 3
affects methylation
ISO
Dieldrin affects the methylation of EEF1AKMT3 gene
CTD
PMID:38995845
NCBI chr 7:64,738,726...64,749,904
Ensembl chr 7:64,740,232...64,750,055
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Efna2
ephrin A2
affects methylation
ISO
Dieldrin affects the methylation of EFNA2 gene
CTD
PMID:38995845
NCBI chr 7:10,167,091...10,177,719
Ensembl chr 7:10,167,091...10,177,719
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Egfr
epidermal growth factor receptor
affects expression
EXP
Dieldrin affects the expression of EGFR mRNA
CTD
PMID:22546817
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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Egln3
egl-9 family hypoxia-inducible factor 3
affects expression
EXP
Dieldrin affects the expression of EGLN3 mRNA
CTD
PMID:22546817
NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:77,385,549...77,411,015
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Egr1
early growth response 1
increases expression
ISO
Dieldrin results in increased expression of EGR1 mRNA
CTD
PMID:31068361
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
G
Egr2
early growth response 2
increases expression
ISO
Dieldrin results in increased expression of EGR2 mRNA
CTD
PMID:31068361
NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
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Ehbp1l1
EH domain binding protein 1-like 1
decreases expression
ISO
Dieldrin results in decreased expression of EHBP1L1 mRNA
CTD
PMID:31068361
NCBI chr 1:212,423,444...212,444,357
Ensembl chr 1:212,423,447...212,443,598
G
Eif2ak4
eukaryotic translation initiation factor 2 alpha kinase 4
increases response to substance
ISO
EIF2AK4 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:125,810,060...125,895,574
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Eif4a1
eukaryotic translation initiation factor 4A1
decreases expression
EXP
Dieldrin results in decreased expression of EIF4A1 mRNA
CTD
PMID:34051100
NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,883,093...54,888,602
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Elane
elastase, neutrophil expressed
affects methylation
ISO
Dieldrin affects the methylation of ELANE gene
CTD
PMID:38995845
NCBI chr 7:10,467,877...10,469,725
Ensembl chr 7:10,467,877...10,469,725
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Elk1
ETS transcription factor ELK1
affects expression
EXP
Dieldrin affects the expression of ELK1 mRNA
CTD
PMID:22546817
NCBI chr X:1,138,826...1,155,713
Ensembl chr X:3,693,293...3,709,249
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Elovl7
ELOVL fatty acid elongase 7
increases expression
EXP
Dieldrin results in increased expression of ELOVL7 mRNA
CTD
PMID:23153324
NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:41,522,738...41,592,020
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Epha3
Eph receptor A3
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA
CTD
PMID:28263720
NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425
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Epha8
Eph receptor A8
multiple interactions affects methylation
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA Dieldrin affects the methylation of EPHA8 gene
CTD
PMID:28263720 PMID:38995845
NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:154,449,566...154,476,966
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Ephb2
Eph receptor B2
affects methylation
ISO
Dieldrin affects the methylation of EPHB2 gene
CTD
PMID:38995845
NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:154,179,065...154,360,615
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Ephx1
epoxide hydrolase 1
multiple interactions
ISO
Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]
CTD
PMID:2043152
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
G
Ephx2
epoxide hydrolase 2
multiple interactions
ISO
Dieldrin promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]
CTD
PMID:2043152
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
G
Eral1
Era-like 12S mitochondrial rRNA chaperone 1
affects expression
EXP
Dieldrin affects the expression of ERAL1 mRNA
CTD
PMID:22546817
NCBI chr10:63,459,774...63,466,829
Ensembl chr10:63,459,774...63,468,225
G
Erbb3
erb-b2 receptor tyrosine kinase 3
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNA
CTD
PMID:19422813
NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120
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Erf
Ets2 repressor factor
affects expression
EXP
Dieldrin affects the expression of ERF mRNA
CTD
PMID:22546817
NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:89,957,760...89,966,213
G
Espl1
extra spindle pole bodies like 1, separase
affects expression
EXP
Dieldrin affects the expression of ESPL1 mRNA
CTD
PMID:22546817
NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570
G
Esr1
estrogen receptor 1
multiple interactions affects binding increases activity decreases expression increases expression
ISO EXP
[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; [Dieldrin co-treated with Chlordan] inhibits the reaction [Estradiol binds to ESR1 protein]; [o,p'-DDT co-treated with Methoxychlor co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Toxaphene co-treated with Dieldrin co-treated with Chlordan] inhibits the reaction [Estradiol binds to ESR1 protein]; Dieldrin binds to and results in increased activity of ESR1 protein; Dieldrin inhibits the reaction [Estradiol binds to ESR1 protein]; Dieldrin inhibits the reaction [Estradiol results in decreased expression of ESR1 mRNA] Dieldrin binds to ESR1 protein Dieldrin results in increased activity of ESR1 protein Dieldrin results in decreased expression of ESR1 protein Dieldrin results in increased expression of ESR1 mRNA
CTD
PMID:9168004 PMID:10774817 PMID:11922773 PMID:14579009 PMID:15064155 PMID:15261991 PMID:16626760 PMID:17174995 PMID:21278053 PMID:21295777 PMID:26022396 More...
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
G
Esr2
estrogen receptor 2
multiple interactions
ISO
Dieldrin binds to and results in decreased activity of ESR2 protein; Dieldrin promotes the reaction [Estradiol results in increased expression of ESR2 mRNA] Dieldrin inhibits the reaction [Estradiol binds to ESR2 protein]
CTD
PMID:15261991 PMID:16626760 PMID:21278053
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
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Esyt1
extended synaptotagmin 1
decreases expression
ISO
Dieldrin results in decreased expression of ESYT1 mRNA
CTD
PMID:31068361
NCBI chr 7:1,513,381...1,530,836
Ensembl chr 7:1,513,381...1,530,732
G
Fadd
Fas associated via death domain
affects expression
EXP
Dieldrin affects the expression of FADD mRNA
CTD
PMID:22546817
NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
G
Faf1
Fas associated factor 1
affects expression
EXP
Dieldrin affects the expression of FAF1 mRNA
CTD
PMID:22546817
NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:129,654,445...130,020,516
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Faim2
Fas apoptotic inhibitory molecule 2
affects expression
EXP
Dieldrin affects the expression of FAIM2 mRNA
CTD
PMID:22546817
NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026
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Fbxo2
F-box protein 2
affects expression
EXP
Dieldrin affects the expression of FBXO2 mRNA
CTD
PMID:22546817
NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:163,875,757...163,881,508
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Fbxw11
F-box and WD repeat domain containing 11
increases response to substance
ISO
FBXW11 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr10:17,737,181...17,834,834
Ensembl chr10:17,720,444...17,834,834
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Fem1b
fem-1 homolog B
affects expression
EXP
Dieldrin affects the expression of FEM1B mRNA
CTD
PMID:22546817
NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:72,160,722...72,173,996
G
Fgf1
fibroblast growth factor 1
affects expression
EXP
Dieldrin affects the expression of FGF1 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393
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Fgf12
fibroblast growth factor 12
decreases expression
EXP
Dieldrin results in decreased expression of FGF12 mRNA
CTD
PMID:19130878
NCBI chr11:85,501,947...86,069,543
Ensembl chr11:85,501,936...86,069,543
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Fgf17
fibroblast growth factor 17
decreases expression
EXP
Dieldrin results in decreased expression of FGF17 mRNA
CTD
PMID:19130878
NCBI chr15:45,711,498...45,717,622
Ensembl chr15:52,121,191...52,132,016
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Fgf19
fibroblast growth factor 19
affects expression
EXP
Dieldrin affects the expression of FGF15 mRNA
CTD
PMID:19130878
NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:209,485,813...209,490,267
G
Fgf2
fibroblast growth factor 2
decreases expression affects expression
EXP
Dieldrin results in decreased expression of FGF2 mRNA Dieldrin affects the expression of FGF2 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
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Fgf21
fibroblast growth factor 21
decreases expression
EXP
Dieldrin results in decreased expression of FGF21 mRNA
CTD
PMID:19130878
NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056
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Fgf22
fibroblast growth factor 22
increases expression
EXP
Dieldrin results in increased expression of FGF22 mRNA
CTD
PMID:19130878
NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:10,597,538...10,600,945
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Fgf8
fibroblast growth factor 8
affects methylation
ISO
Dieldrin affects the methylation of FGF8 gene
CTD
PMID:38995845
NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605
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Fgf9
fibroblast growth factor 9
increases expression affects expression
EXP
Dieldrin results in increased expression of FGF9 mRNA Dieldrin affects the expression of FGF9 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926
G
Fgfr1
Fibroblast growth factor receptor 1
affects expression
EXP
Dieldrin affects the expression of FGFR1 mRNA
CTD
PMID:19130878
NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855
G
Fgfr2
fibroblast growth factor receptor 2
affects methylation
ISO
Dieldrin affects the methylation of FGFR2 gene
CTD
PMID:38995845
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
G
Fgfr4
fibroblast growth factor receptor 4
affects expression
EXP
Dieldrin affects the expression of FGFR4 mRNA
CTD
PMID:19130878
NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389
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Fhod3
formin homology 2 domain containing 3
affects methylation
ISO
Dieldrin affects the methylation of FHOD3 gene
CTD
PMID:38995845
NCBI chr18:16,267,830...16,700,508
Ensembl chr18:16,267,977...16,700,508
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Fis1
fission, mitochondrial 1
affects expression
EXP
Dieldrin affects the expression of FIS1 mRNA
CTD
PMID:22546817
NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335
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Flrt1
fibronectin leucine rich transmembrane protein 1
affects methylation
ISO
Dieldrin affects the methylation of FLRT1 gene
CTD
PMID:38995845
NCBI chr 1:213,704,983...213,782,958
Ensembl chr 1:213,704,038...213,782,981
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression
ISO
1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; BX795 promotes the reaction [Dieldrin results in increased expression of FOS mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; Wortmannin inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]
CTD
PMID:31068361
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Dieldrin results in increased expression of FOSB mRNA
CTD
PMID:31068361
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477
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Fosl2
FOS like 2, AP-1 transcription factor subunit
increases expression
ISO
Dieldrin results in increased expression of FOSL2 mRNA
CTD
PMID:31068361
NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406
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Foxn3
forkhead box N3
affects expression
EXP
Dieldrin affects the expression of FOXN3 mRNA
CTD
PMID:22546817
NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:124,195,701...124,572,040
G
Foxo3
forkhead box O3
affects expression affects methylation
EXP ISO
Dieldrin affects the expression of FOXO3 mRNA Dieldrin affects the methylation of FOXO3 gene
CTD
PMID:22546817 PMID:38995845
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
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Foxp1
forkhead box P1
affects methylation
ISO
Dieldrin affects the methylation of FOXP1 gene
CTD
PMID:38995845
NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:133,122,055...133,500,272
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Frmd4b
FERM domain containing 4B
affects methylation
ISO
Dieldrin affects the methylation of FRMD4B gene
CTD
PMID:38995845
NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:131,452,365...131,640,287
G
Fxr1
FMR1 autosomal homolog 1
affects expression
EXP
Dieldrin affects the expression of FXR1 mRNA
CTD
PMID:22546817
NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:118,811,980...118,867,027
G
Fyn
FYN proto-oncogene, Src family tyrosine kinase
increases activity multiple interactions affects expression
EXP
Dieldrin results in increased activity of FYN protein FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; FYN protein promotes the reaction [Dieldrin results in increased phosphorylation of PRKCD protein] Dieldrin affects the expression of FYN mRNA
CTD
PMID:21801747 PMID:22546817
NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479
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Fzd1
frizzled class receptor 1
increases expression
EXP
Dieldrin results in increased expression of FZD1 mRNA
CTD
PMID:19130878
NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176
G
Fzd2
frizzled class receptor 2
increases expression
EXP
Dieldrin results in increased expression of FZD2 mRNA
CTD
PMID:19130878
NCBI chr10:88,061,988...88,063,898
Ensembl chr10:88,061,667...88,065,396
G
Fzd3
frizzled class receptor 3
decreases expression
EXP
Dieldrin results in decreased expression of FZD3 mRNA
CTD
PMID:19130878
NCBI chr15:43,596,962...43,664,047
Ensembl chr15:43,596,965...43,663,960
G
Fzd6
frizzled class receptor 6
affects expression
EXP
Dieldrin affects the expression of FZD6 mRNA
CTD
PMID:19130878
NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680
G
Fzd7
frizzled class receptor 7
affects expression
EXP
Dieldrin affects the expression of FZD7 mRNA
CTD
PMID:19130878
NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:68,411,259...68,432,585
G
Fzd9
frizzled class receptor 9
decreases expression
EXP
Dieldrin results in decreased expression of FZD9 mRNA
CTD
PMID:19130878
NCBI chr12:27,063,640...27,065,954
Ensembl chr12:27,063,415...27,074,485
G
Fzr1
fizzy and cell division cycle 20 related 1
affects expression
EXP
Dieldrin affects the expression of FZR1 mRNA
CTD
PMID:22546817
NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,989,769...8,995,199
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G6pd
glucose-6-phosphate dehydrogenase
affects expression
EXP
Dieldrin affects the expression of G6PD mRNA
CTD
PMID:22546817
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
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Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions decreases expression
ISO EXP
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] Dieldrin results in decreased expression of GABRA1 mRNA
CTD
PMID:9600394 PMID:14637376
NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442
G
Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
multiple interactions
ISO
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:14637376
NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,450,683...37,587,457
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:14637376
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:27,438,238...27,655,171
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
decreases expression increases expression
EXP
Dieldrin results in decreased expression of GABRB3 mRNA Dieldrin results in increased expression of GABRB3 mRNA
CTD
PMID:9302086 PMID:9600394
NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:117,431,842...117,836,725
G
Gabrg1
gamma-aminobutyric acid type A receptor subunit gamma 1
decreases expression
EXP
Dieldrin results in decreased expression of GABRG1 mRNA
CTD
PMID:9600394
NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,750,292...37,989,945
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions decreases expression
ISO EXP
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] Dieldrin results in decreased expression of GABRG2 mRNA
CTD
PMID:9302086 PMID:14637376
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,876,926...26,965,523
G
Gabrr1
gamma-aminobutyric acid type A receptor subunit rho 1
affects binding
ISO
Dieldrin binds to GABRR1 protein
CTD
PMID:11879973
NCBI chr 5:52,320,475...52,357,549
Ensembl chr 5:52,320,475...52,357,549
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
affects expression
EXP
Dieldrin affects the expression of GADD45A mRNA
CTD
PMID:22546817
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
affects expression
EXP
Dieldrin affects the expression of GADD45G mRNA
CTD
PMID:22546817
NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369
G
Gal3st1
galactose-3-O-sulfotransferase 1
affects methylation
ISO
Dieldrin affects the methylation of GAL3ST1 gene
CTD
PMID:38995845
NCBI chr14:83,094,265...83,109,992
Ensembl chr14:83,094,385...83,109,978
G
Galnt18
polypeptide N-acetylgalactosaminyltransferase 18
affects methylation
ISO
Dieldrin affects the methylation of GALNT18 gene
CTD
PMID:38995845
NCBI chr 1:175,027,832...175,338,883
Ensembl chr 1:175,027,839...175,338,883
G
Galnt2
polypeptide N-acetylgalactosaminyltransferase 2
affects methylation
ISO
Dieldrin affects the methylation of GALNT2 gene
CTD
PMID:38995845
NCBI chr19:69,110,657...69,222,237
Ensembl chr19:69,110,657...69,222,237
G
Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
increases expression
ISO
Dieldrin results in increased expression of GALNT3 mRNA
CTD
PMID:31068361
NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323
G
Gamt
guanidinoacetate N-methyltransferase
affects methylation
ISO
Dieldrin affects the methylation of GAMT gene
CTD
PMID:38995845
NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083
G
Gap43
growth associated protein 43
multiple interactions
EXP
Dieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]
CTD
PMID:28385489
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797
G
Gdf15
growth differentiation factor 15
affects methylation
ISO
Dieldrin affects the methylation of GDF15 gene
CTD
PMID:38995845
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
G
Get1
guided entry of tail-anchored proteins factor 1
decreases expression
ISO
Dieldrin results in decreased expression of WRB mRNA
CTD
PMID:31068361
NCBI chr11:35,438,555...35,460,156
Ensembl chr11:48,915,289...48,929,416
G
Gfap
glial fibrillary acidic protein
multiple interactions
ISO
Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]
CTD
PMID:16809432
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
G
Gfi1b
growth factor independent 1B transcriptional repressor
affects expression
EXP
Dieldrin affects the expression of GFI1B mRNA
CTD
PMID:22546817
NCBI chr 3:11,940,232...11,952,989
Ensembl chr 3:32,338,214...32,350,916
G
Gfra1
GDNF family receptor alpha 1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA
CTD
PMID:28263720
NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501
G
Gja1
gap junction protein, alpha 1
multiple interactions decreases expression decreases phosphorylation
ISO EXP
[Dieldrin co-treated with 2,4,5,2',4',5'-hexabromobiphenyl] results in decreased expression of GJA1 protein; [Dieldrin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GJA1 protein Dieldrin results in decreased expression of GJA1 protein Dieldrin results in decreased expression of GJA1 mRNA; Dieldrin results in decreased expression of GJA1 protein; Dieldrin results in decreased expression of GJA1 protein modified form chaetoglobosins inhibits the reaction [Dieldrin results in decreased phosphorylation of GJA1 protein]
CTD
PMID:8068183 PMID:8820588 PMID:15082077 PMID:18040759
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
G
Gjb2
gap junction protein, beta 2
decreases expression
EXP
Dieldrin results in decreased expression of GJB2 protein
CTD
PMID:8068183
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877
G
Gnas
GNAS complex locus
affects methylation
ISO
Dieldrin affects the methylation of GNAS gene
CTD
PMID:38995845
NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536
G
Gnrh1
gonadotropin releasing hormone 1
affects expression
EXP
Dieldrin affects the expression of GNRH1 mRNA
CTD
PMID:22546817
NCBI chr15:41,972,482...41,976,690
Ensembl chr15:46,148,301...46,148,977 Ensembl chr15:46,148,301...46,148,977
G
Gp1bb
glycoprotein Ib platelet subunit beta
affects methylation
ISO
Dieldrin affects the methylation of GP1BB gene
CTD
PMID:38995845
NCBI chr11:95,882,561...95,883,738
G
Gpx1
glutathione peroxidase 1
decreases expression multiple interactions affects expression
EXP ISO
Dieldrin results in decreased expression of GPX1 mRNA GPX1 protein results in decreased activity of and results in decreased susceptibility to Dieldrin Dieldrin affects the expression of GPX1 mRNA
CTD
PMID:12621067 PMID:19440498 PMID:22546817
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx3
glutathione peroxidase 3
increases expression
EXP
Dieldrin results in increased expression of GPX3 mRNA
CTD
PMID:19440498
NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
G
Gpx4
glutathione peroxidase 4
increases expression
EXP
Dieldrin results in increased expression of GPX4 mRNA
CTD
PMID:19440498
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Gpx6
glutathione peroxidase 6
decreases expression
EXP
Dieldrin results in decreased expression of GPX6 mRNA
CTD
PMID:19440498
NCBI chr17:48,104,197...48,111,816
Ensembl chr17:48,104,197...48,111,007
G
Gramd1c
GRAM domain containing 1C
affects methylation
ISO
Dieldrin affects the methylation of GRAMD1C gene
CTD
PMID:38995845
NCBI chr11:56,633,229...56,718,570
Ensembl chr11:70,139,184...70,224,478
G
Grb10
growth factor receptor bound protein 10
affects methylation
ISO
Dieldrin affects the methylation of GRB10 gene
CTD
PMID:38995845
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
G
Gria1
glutamate ionotropic receptor AMPA type subunit 1
increases expression
EXP
Dieldrin results in increased expression of GRIA1 mRNA
CTD
PMID:19440498
NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309
G
Gria2
glutamate ionotropic receptor AMPA type subunit 2
decreases expression
EXP
Dieldrin results in decreased expression of GRIA2 mRNA
CTD
PMID:19440498
NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616
G
Grid1
glutamate ionotropic receptor delta type subunit 1
affects expression
EXP
Dieldrin affects the expression of GRID1 mRNA
CTD
PMID:19440498
NCBI chr16:10,145,018...10,894,184
Ensembl chr16:10,144,964...10,891,946
G
Grik3
glutamate ionotropic receptor kainate type subunit 3
decreases expression
EXP
Dieldrin results in decreased expression of GRIK3 mRNA
CTD
PMID:19440498
NCBI chr 5:143,052,442...143,268,873
Ensembl chr 5:143,052,442...143,268,873
G
Grin1
glutamate ionotropic receptor NMDA type subunit 1
increases uptake increases expression
ISO EXP
Dieldrin results in increased uptake of GRIN1 protein Dieldrin results in increased expression of GRIN1 mRNA
CTD
PMID:19440498 PMID:19812363
NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
decreases expression
EXP
Dieldrin results in decreased expression of GRIN2B mRNA
CTD
PMID:19440498
NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570
G
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
affects expression
EXP
Dieldrin affects the expression of GRIN2C mRNA
CTD
PMID:19440498
NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,987,513...101,005,409
G
Grin3b
glutamate ionotropic receptor NMDA type subunit 3B
affects expression
EXP
Dieldrin affects the expression of GRIN3B mRNA
CTD
PMID:19440498
NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:10,381,496...10,387,817
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
increases expression
EXP
Dieldrin results in increased expression of GRINA mRNA
CTD
PMID:19440498
NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
G
Grk2
G protein-coupled receptor kinase 2
increases expression
EXP
Dieldrin results in increased expression of GRK2 mRNA
CTD
PMID:18812211
NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015
G
Grm5
glutamate metabotropic receptor 5
decreases expression
ISO
Dieldrin results in decreased expression of GRM5 protein
CTD
PMID:19812363
NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:150,733,678...151,296,649
G
Gsta5
glutathione S-transferase alpha 5
affects expression increases expression
EXP
Dieldrin affects the expression of GSTA5 mRNA Dieldrin results in increased expression of GSTA5 mRNA
CTD
PMID:19440498
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
G
Gstm4
glutathione S-transferase mu 4
affects expression
EXP
Dieldrin affects the expression of GSTM4 mRNA
CTD
PMID:19440498
NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638
G
Gstm5
glutathione S-transferase, mu 5
affects expression
EXP
Dieldrin affects the expression of GSTM3 mRNA
CTD
PMID:19440498
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
G
Gstm6
glutathione S-transferase, mu 6
affects expression
EXP
Dieldrin affects the expression of GSTM6 mRNA
CTD
PMID:19440498
NCBI chr 2:198,267,734...198,272,508
G
Gsto1
glutathione S-transferase omega 1
increases expression
EXP
Dieldrin results in increased expression of GSTO1 mRNA
CTD
PMID:19440498
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
G
Gsto2
glutathione S-transferase omega 2
affects expression
EXP
Dieldrin affects the expression of GSTO2 mRNA
CTD
PMID:19440498
NCBI chr 1:256,673,376...256,695,154
Ensembl chr 1:256,673,274...256,695,146
G
Gstp1
glutathione S-transferase pi 1
increases expression
EXP
Dieldrin results in increased expression of GSTP2 mRNA
CTD
PMID:19440498
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Gstt3
glutathione S-transferase, theta 3
decreases expression
EXP
Dieldrin results in decreased expression of GSTT3 mRNA
CTD
PMID:19440498
NCBI chr20:12,873,618...12,881,974
Ensembl chr20:12,874,374...12,881,973
G
H2ac25
H2A clustered histone 25
increases expression
ISO
Dieldrin results in increased expression of H2AC25 mRNA
CTD
PMID:31068361
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:44,233,181...44,241,197
G
H2ac4
H2A clustered histone 4
increases expression
ISO
Dieldrin results in increased expression of HIST1H2AC mRNA
CTD
PMID:31068361
NCBI chr17:42,799,884...42,800,387
Ensembl chr17:47,495,546...47,496,173
G
H2az1
H2A.Z variant histone 1
increases expression
EXP
Dieldrin results in increased expression of H2AZ1 mRNA
CTD
PMID:23153324
NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:229,028,843...229,031,411
G
Haus1
HAUS augmin-like complex, subunit 1
affects expression
EXP
Dieldrin affects the expression of HAUS1 mRNA
CTD
PMID:22546817
NCBI chr18:71,275,417...71,286,626
Ensembl chr18:73,548,669...73,565,761
G
Hdac9
histone deacetylase 9
affects methylation
ISO
Dieldrin affects the methylation of HDAC9 gene
CTD
PMID:38995845
NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:56,490,988...57,351,835
G
Heg1
heart development protein with EGF-like domains 1
affects methylation
ISO
Dieldrin affects the methylation of HEG1 gene
CTD
PMID:38995845
NCBI chr11:80,512,096...80,600,150
Ensembl chr11:80,512,096...80,600,092
G
Hibadh
3-hydroxyisobutyrate dehydrogenase
decreases expression
EXP
Dieldrin results in decreased expression of HIBADH mRNA
CTD
PMID:23153324
NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:82,979,765...83,111,242
G
Hipk1
homeodomain interacting protein kinase 1
affects expression
EXP
Dieldrin affects the expression of HIPK1 mRNA
CTD
PMID:22546817
NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:193,937,261...193,975,164
G
Hk2
hexokinase 2
increases expression
EXP
Dieldrin results in increased expression of HK2 mRNA
CTD
PMID:23153324
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
G
Hmox1
heme oxygenase 1
multiple interactions increases expression affects expression
ISO EXP
Dieldrin results in increased expression of and results in increased activity of HMOX1 protein; SB 203580 inhibits the reaction [Dieldrin results in increased expression of HMOX1 protein] Dieldrin results in increased expression of HMOX1 mRNA Dieldrin affects the expression of HMOX1 mRNA
CTD
PMID:11181820 PMID:15770161 PMID:22546817
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hoxa2
homeobox A2
affects methylation
ISO
Dieldrin affects the methylation of HOXA2 gene
CTD
PMID:38995845
NCBI chr 4:82,593,389...82,597,589
Ensembl chr 4:82,593,389...82,595,692
G
Hoxa3
homeobox A3
affects methylation
ISO
Dieldrin affects the methylation of HOXA3 gene
CTD
PMID:38995845
NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:82,599,860...82,643,831
G
Hoxa4
homeo box A4
affects methylation
ISO
Dieldrin affects the methylation of HOXA4 gene
CTD
PMID:38995845
NCBI chr 4:81,289,677...81,291,685
Ensembl chr 4:82,620,299...82,622,302
G
Hoxa6
homeobox A6
affects methylation
ISO
Dieldrin affects the methylation of HOXA6 gene
CTD
PMID:38995845
NCBI chr 4:81,304,918...81,313,184
G
Hrk
harakiri, BCL2 interacting protein
affects expression
EXP
Dieldrin affects the expression of HRK mRNA
CTD
PMID:22546817
NCBI chr12:38,387,484...38,409,652
Ensembl chr12:44,048,402...44,070,561
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
affects expression
EXP
Dieldrin affects the expression of HSPA1A mRNA
CTD
PMID:22546817
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
Dieldrin results in increased expression of HSPA1B mRNA
CTD
PMID:31068361
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979
G
Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
Dieldrin results in increased expression of HSPA6 mRNA
CTD
PMID:31068361
NCBI chr13:85,805,911...85,807,052
G
Hspa9
heat shock protein family A (Hsp70) member 9
affects expression
EXP
Dieldrin affects the expression of HSPA9 mRNA
CTD
PMID:22546817
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,804,774...26,828,398
G
Htr1a
5-hydroxytryptamine receptor 1A
decreases expression
EXP
Dieldrin results in decreased expression of HTR1A mRNA
CTD
PMID:18835401
NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760
G
Htr1d
5-hydroxytryptamine receptor 1D
affects expression
EXP
Dieldrin affects the expression of HTR1D mRNA
CTD
PMID:18835401
NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:153,939,516...153,960,012
G
Htr2b
5-hydroxytryptamine receptor 2B
affects expression
EXP
Dieldrin affects the expression of HTR2B mRNA
CTD
PMID:18835401
NCBI chr 9:94,184,442...94,206,851
Ensembl chr 9:94,190,109...94,204,087
G
Htr2c
5-hydroxytryptamine receptor 2C
affects expression
EXP
Dieldrin affects the expression of HTR2C mRNA
CTD
PMID:18835401
NCBI chr X:115,453,190...115,682,325
Ensembl chr X:115,452,842...115,682,324
G
Htr3a
5-hydroxytryptamine receptor 3A
decreases expression
EXP
Dieldrin results in decreased expression of HTR3A mRNA
CTD
PMID:18835401
NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884
G
Htr3b
5-hydroxytryptamine receptor 3B
decreases expression
EXP
Dieldrin results in decreased expression of HTR3B mRNA
CTD
PMID:18835401
NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:58,175,101...58,204,939
G
Htr5a
5-hydroxytryptamine receptor 5A
increases expression
EXP
Dieldrin results in increased expression of HTR5A mRNA
CTD
PMID:18835401
NCBI chr 4:8,178,802...8,188,485
Ensembl chr 4:8,178,802...8,200,482
G
Htr5b
5-hydroxytryptamine (serotonin) receptor 5B
decreases expression
EXP
Dieldrin results in decreased expression of HTR5B mRNA
CTD
PMID:18835401
NCBI chr13:35,239,662...35,252,586
Ensembl chr13:35,239,662...35,252,586
G
Htr6
5-hydroxytryptamine receptor 6
affects expression
EXP
Dieldrin affects the expression of HTR6 mRNA
CTD
PMID:18835401
NCBI chr 5:156,579,901...156,595,147
Ensembl chr 5:156,579,901...156,595,147
G
Icos
inducible T-cell co-stimulator
increases expression
ISO
Dieldrin results in increased expression of ICOS mRNA
CTD
PMID:31068361
NCBI chr 9:69,862,042...69,900,864
Ensembl chr 9:69,877,785...69,900,960
G
Id2
inhibitor of DNA binding 2
affects expression
EXP
Dieldrin affects the expression of ID2 mRNA
CTD
PMID:22546817
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
G
Idh3b
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
affects expression
EXP
Dieldrin affects the expression of IDH3B mRNA
CTD
PMID:22546817
NCBI chr 3:137,934,971...137,940,275
Ensembl chr 3:137,934,697...137,940,107
G
Ier2
immediate early response 2
increases expression
ISO
Dieldrin results in increased expression of IER2 mRNA
CTD
PMID:31068361
NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708
G
Ier3
immediate early response 3
increases expression
ISO
Dieldrin results in increased expression of IER3 mRNA
CTD
PMID:31068361
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
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Ifi35
interferon-induced protein 35
decreases expression
EXP
Dieldrin results in decreased expression of IFI35 mRNA
CTD
PMID:34051100
NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750
G
Ifi44
interferon-induced protein 44
decreases expression
EXP
Dieldrin results in decreased expression of IFI44 mRNA
CTD
PMID:34051100
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:243,286,052...243,306,877
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Ifi47
interferon gamma inducible protein 47
decreases expression
EXP
Dieldrin results in decreased expression of IFI47 mRNA
CTD
PMID:34051100
NCBI chr10:33,297,618...33,305,248
Ensembl chr10:33,776,399...33,806,372
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Ifih1
interferon induced with helicase C domain 1
decreases expression
EXP
Dieldrin results in decreased expression of IFIH1 mRNA
CTD
PMID:34051100
NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968
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Ifit2
interferon-induced protein with tetratricopeptide repeats 2
decreases expression multiple interactions
EXP ISO
Dieldrin results in decreased expression of IFIT2 mRNA Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]
CTD
PMID:34051100
NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:241,515,709...241,521,798
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
decreases expression
EXP
Dieldrin results in decreased expression of IFIT3 mRNA
CTD
PMID:34051100
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
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Ifitm1
interferon induced transmembrane protein 1
affects expression
EXP
Dieldrin affects the expression of IFITM1 mRNA
CTD
PMID:22546817
NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776
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Ifitm3
interferon induced transmembrane protein 3
decreases expression
EXP
Dieldrin results in decreased expression of IFITM3 mRNA
CTD
PMID:34051100
NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:205,481,168...205,547,920
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Igf1
insulin-like growth factor 1
affects expression
EXP
Dieldrin affects the expression of IGF1 mRNA
CTD
PMID:22546817
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
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Il10
interleukin 10
affects expression
EXP
Dieldrin affects the expression of IL10 mRNA
CTD
PMID:22546817
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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Il13
interleukin 13
affects methylation
ISO
Dieldrin affects the methylation of IL13 gene
CTD
PMID:38995845
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
G
Il18
interleukin 18
affects expression
EXP
Dieldrin affects the expression of IL18 mRNA
CTD
PMID:22546817
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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Il1b
interleukin 1 beta
increases expression
EXP
Dieldrin results in increased expression of IL1B mRNA
CTD
PMID:15135310
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il2
interleukin 2
increases expression
ISO
Dieldrin results in increased expression of IL2 mRNA
CTD
PMID:31068361
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il6
interleukin 6
increases expression
EXP
Dieldrin results in increased expression of IL6 protein
CTD
PMID:13129777
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Inpp5d
inositol polyphosphate-5-phosphatase D
affects expression
EXP
Dieldrin affects the expression of INPP5D mRNA
CTD
PMID:22546817
NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589
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Inpp5f
inositol polyphosphate-5-phosphatase F
affects methylation
ISO
Dieldrin affects the methylation of INPP5F gene
CTD
PMID:38995845
NCBI chr 1:192,620,891...192,700,681
Ensembl chr 1:192,620,891...192,700,681
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Insig2
insulin induced gene 2
decreases expression
EXP
Dieldrin results in decreased expression of INSIG2 mRNA
CTD
PMID:23153324
NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658
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Irak3
interleukin-1 receptor-associated kinase 3
affects expression
EXP
Dieldrin affects the expression of IRAK3 mRNA
CTD
PMID:22546817
NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706
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Irf7
interferon regulatory factor 7
decreases expression
EXP
Dieldrin results in decreased expression of IRF7 mRNA
CTD
PMID:34051100
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
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Irf9
interferon regulatory factor 9
decreases expression
EXP
Dieldrin results in decreased expression of IRF9 mRNA
CTD
PMID:34051100
NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879
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Irgm
immunity-related GTPase M
decreases expression
EXP
Dieldrin results in decreased expression of IRGM mRNA
CTD
PMID:34051100
NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228
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Isg15
ISG15 ubiquitin-like modifier
affects expression decreases expression
EXP
Dieldrin affects the expression of ISG15 mRNA Dieldrin results in decreased expression of ISG15 mRNA
CTD
PMID:22546817 PMID:34051100
NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
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Isg20
interferon stimulated exonuclease gene 20
decreases expression
EXP
Dieldrin results in decreased expression of ISG20 mRNA
CTD
PMID:34051100
NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:142,236,137...142,246,401
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Itm2b
integral membrane protein 2B
affects expression
EXP
Dieldrin affects the expression of ITM2B mRNA
CTD
PMID:22546817
NCBI chr15:54,955,549...54,978,455
Ensembl chr15:54,955,552...54,978,455
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Itsn1
intersectin 1
affects methylation
ISO
Dieldrin affects the methylation of ITSN1 gene
CTD
PMID:38995845
NCBI chr11:44,464,515...44,646,598
Ensembl chr11:44,513,186...44,646,598
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Jak2
Janus kinase 2
decreases expression
EXP
Dieldrin results in decreased expression of JAK2 mRNA
CTD
PMID:34051100
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
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Jmjd6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
affects expression
EXP
Dieldrin affects the expression of JMJD6 mRNA
CTD
PMID:22546817
NCBI chr10:102,539,935...102,545,986
Ensembl chr10:102,539,894...102,545,986
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation affects expression decreases response to substance increases expression
ISO EXP
Dieldrin results in increased phosphorylation of JUN protein Dieldrin affects the expression of JUN mRNA JUN gene mutant form results in decreased susceptibility to Dieldrin Dieldrin results in increased expression of JUN mRNA
CTD
PMID:15888667 PMID:22546817 PMID:31068361 PMID:32421776
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
affects expression increases expression
EXP ISO
Dieldrin affects the expression of JUNB mRNA Dieldrin results in increased expression of JUNB mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
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Jund
JunD proto-oncogene, AP-1 transcription factor subunit
affects expression increases expression
EXP ISO
Dieldrin affects the expression of JUND mRNA Dieldrin results in increased expression of JUND mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
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Katna1
katanin catalytic subunit A1
affects expression
EXP
Dieldrin affects the expression of KATNA1 mRNA
CTD
PMID:22546817
NCBI chr 1:2,202,501...2,244,132
Ensembl chr 1:4,022,876...4,064,512
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Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
affects methylation
ISO
Dieldrin affects the methylation of KCNJ10 gene
CTD
PMID:38995845
NCBI chr13:87,334,510...87,367,747
Ensembl chr13:87,334,216...87,368,678
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Kif18b
kinesin family member 18B
increases expression
EXP
Dieldrin results in increased expression of KIF18B mRNA
CTD
PMID:23153324
NCBI chr10:87,870,424...87,889,895
Ensembl chr10:88,370,524...88,389,691
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Kif20b
kinesin family member 20B
affects expression
EXP
Dieldrin affects the expression of KIF20B mRNA
CTD
PMID:22546817
NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:241,840,987...241,896,451
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Kit
KIT proto-oncogene receptor tyrosine kinase
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
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Klf10
KLF transcription factor 10
affects expression
EXP
Dieldrin affects the expression of KLF10 mRNA
CTD
PMID:22546817
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:71,350,573...71,358,948
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Klf4
KLF transcription factor 4
increases expression
ISO
Dieldrin results in increased expression of KLF4 mRNA
CTD
PMID:31068361
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592
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Klf6
KLF transcription factor 6
increases expression
ISO
Dieldrin results in increased expression of KLF6 mRNA
CTD
PMID:31068361
NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
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Klf9
KLF transcription factor 9
decreases expression
EXP
Dieldrin results in decreased expression of KLF9 mRNA
CTD
PMID:23153324
NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:230,126,646...230,151,641
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Klhl42
kelch-like family, member 42
decreases response to substance
ISO
KLHL42 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:181,735,244...181,757,013
G
Klk1b3
kallikrein 1-related peptidase B3
increases expression
EXP
Dieldrin results in increased expression of KLK1B3 mRNA
CTD
PMID:19130878
NCBI chr 1:94,709,105...94,713,308
Ensembl chr 1:103,845,603...103,849,855
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Lamb1
laminin subunit beta 1
increases expression
EXP
Dieldrin results in increased expression of LAMB1 mRNA
CTD
PMID:23153324
NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:53,563,073...53,630,760
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Lax1
lymphocyte transmembrane adaptor 1
increases expression
ISO
Dieldrin results in increased expression of LAX1 mRNA
CTD
PMID:31068361
NCBI chr13:45,134,825...45,145,381
Ensembl chr13:47,686,849...47,697,460
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Lcn2
lipocalin 2
affects expression
EXP
Dieldrin affects the expression of LCN2 mRNA
CTD
PMID:22546817
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
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Ldlr
low density lipoprotein receptor
increases expression
ISO
Dieldrin results in increased expression of LDLR mRNA
CTD
PMID:31068361
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
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Lgals12
galectin 12
affects expression
EXP
Dieldrin affects the expression of LGALS12 mRNA
CTD
PMID:22546817
NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:214,261,216...214,271,910
G
Lgals7
galectin 7
affects expression
EXP
Dieldrin affects the expression of LGALS7 mRNA
CTD
PMID:22546817
NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:93,273,836...93,279,528
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Lgi1
leucine-rich, glioma inactivated 1
affects expression
EXP
Dieldrin affects the expression of LGI1 mRNA
CTD
PMID:22546817
NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:245,455,599...245,499,095
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Litaf
lipopolysaccharide-induced TNF factor
affects expression
EXP
Dieldrin affects the expression of LITAF mRNA
CTD
PMID:22546817
NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930
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Lmbrd1
LMBR1 domain containing 1
decreases expression
EXP
Dieldrin results in decreased expression of LMBRD1 mRNA
CTD
PMID:23153324
NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:34,577,616...34,674,428
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Lmna
lamin A/C
affects methylation
ISO
Dieldrin affects the methylation of LMNA gene
CTD
PMID:38995845
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072
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Lmnb1
lamin B1
increases expression
EXP
Dieldrin results in increased expression of LMNB1 mRNA
CTD
PMID:23153324
NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283
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Lmx1b
LIM homeobox transcription factor 1 beta
affects methylation
ISO
Dieldrin affects the methylation of LMX1B gene
CTD
PMID:30859219 PMID:38995845
NCBI chr 3:37,257,025...37,338,675
Ensembl chr 3:37,259,855...37,338,557
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Lrp8
LDL receptor related protein 8
affects methylation
ISO
Dieldrin affects the methylation of LRP8 gene
CTD
PMID:38995845
NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207
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Lrrc1
leucine rich repeat containing 1
increases expression
EXP
Dieldrin results in increased expression of LRRC1 mRNA
CTD
PMID:23153324
NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:87,119,975...87,286,853
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Lrrc2
leucine rich repeat containing 2
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA
CTD
PMID:28263720
NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:119,814,509...119,847,583
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Lrrc4b
leucine rich repeat containing 4B
affects methylation
ISO
Dieldrin affects the methylation of LRRC4B gene
CTD
PMID:38995845
NCBI chr 1:94,922,034...94,956,309
Ensembl chr 1:104,072,128...104,093,298
G
Lsp1
lymphocyte-specific protein 1
affects expression
EXP
Dieldrin affects the expression of LSP1 mRNA
CTD
PMID:22546817
NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:207,044,159...207,077,893
G
Macrod1
mono-ADP ribosylhydrolase 1
affects methylation
ISO
Dieldrin affects the methylation of MACROD1 gene
CTD
PMID:38995845
NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348
G
Mafk
MAF bZIP transcription factor K
affects expression
EXP
Dieldrin affects the expression of MAFK mRNA
CTD
PMID:22546817
NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192
G
Mageh1
MAGE family member H1
affects expression
EXP
Dieldrin affects the expression of MAGEH1 mRNA
CTD
PMID:22546817
NCBI chr X:18,350,015...18,351,271
Ensembl chr X:21,718,669...21,727,219
G
Map2
microtubule-associated protein 2
multiple interactions
ISO
Dieldrin promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of MAP2 mRNA]
CTD
PMID:32949729
NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K1 protein
CTD
PMID:15888667
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
G
Map2k2
mitogen activated protein kinase kinase 2
multiple interactions affects methylation
ISO
Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K2 protein Dieldrin affects the methylation of MAP2K2 gene
CTD
PMID:15888667 PMID:38995845
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
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Map3k10
mitogen activated protein kinase kinase kinase 10
affects expression
EXP
Dieldrin affects the expression of MAP3K10 mRNA
CTD
PMID:22546817
NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:92,083,376...92,101,676
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Map3k14
mitogen-activated protein kinase kinase kinase 14
increases expression
ISO
Dieldrin results in increased expression of MAP3K14 mRNA
CTD
PMID:31068361
NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,665,417...88,715,592
G
Map3k5
mitogen-activated protein kinase kinase kinase 5
affects methylation
ISO
Dieldrin affects the methylation of MAP3K5 gene
CTD
PMID:38995845
NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898
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Map3k6
mitogen-activated protein kinase kinase kinase 6
affects expression
EXP
Dieldrin affects the expression of MAP3K6 mRNA
CTD
PMID:22546817
NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
ISO EXP
calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK1 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein] 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein] Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK1 protein]
CTD
PMID:15531431 PMID:15888667 PMID:17174995 PMID:18040759 PMID:21278053 PMID:35137321 More...
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
G
Mapk12
mitogen-activated protein kinase 12
affects expression
EXP
Dieldrin affects the expression of MAPK12 mRNA
CTD
PMID:22546817
NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307
G
Mapk13
mitogen activated protein kinase 13
affects expression
EXP
Dieldrin affects the expression of MAPK13 mRNA
CTD
PMID:22546817
NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191
G
Mapk14
mitogen activated protein kinase 14
affects methylation
ISO
Dieldrin affects the methylation of MAPK14 gene
CTD
PMID:38995845
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
G
Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation affects expression
ISO EXP
calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK3 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] Dieldrin affects the expression of MAPK3 mRNA Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK3 protein]
CTD
PMID:15531431 PMID:15888667 PMID:18040759 PMID:21278053 PMID:22546817 PMID:35137321 More...
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
affects expression
EXP
Dieldrin affects the expression of MAPK8IP1 mRNA
CTD
PMID:22546817
NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368
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Mcl1
MCL1 apoptosis regulator, BCL2 family member
increases expression
ISO
Dieldrin results in increased expression of MCL1 mRNA
CTD
PMID:31068361
NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
G
Mcoln2
mucolipin TRP cation channel 2
affects response to substance
ISO
MCOLN2 gene SNP affects the susceptibility to Dieldrin
CTD
PMID:25622337
NCBI chr 2:237,714,100...237,762,979
Ensembl chr 2:237,714,084...237,762,978
G
Mcrs1
microspherule protein 1
affects expression
EXP
Dieldrin affects the expression of MCRS1 mRNA
CTD
PMID:22546817
NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:132,262,722...132,271,533
G
Mdc1
mediator of DNA damage checkpoint 1
affects expression
EXP
Dieldrin affects the expression of MDC1 mRNA
CTD
PMID:22546817
NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960
G
Mdk
midkine
affects expression
EXP
Dieldrin affects the expression of MDK mRNA
CTD
PMID:22546817
NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743
G
Mdm2
MDM2 proto-oncogene
affects expression affects methylation
EXP ISO
Dieldrin affects the expression of MDM2 mRNA Dieldrin affects the methylation of MDM2 gene
CTD
PMID:22546817 PMID:38995845
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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Mdm4
MDM4 regulator of p53
affects expression
EXP
Dieldrin affects the expression of MDM4 mRNA
CTD
PMID:22546817
NCBI chr13:44,432,596...44,516,165
Ensembl chr13:46,958,298...47,026,372
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Men1
menin 1
affects expression
EXP
Dieldrin affects the expression of MEN1 mRNA
CTD
PMID:22546817
NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:213,068,166...213,074,120
G
Mertk
MER proto-oncogene, tyrosine kinase
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA
CTD
PMID:28263720
NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192
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Mgll
monoglyceride lipase
affects methylation
ISO
Dieldrin affects the methylation of MGLL gene
CTD
PMID:38995845
NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440
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Mgst2
microsomal glutathione S-transferase 2
decreases expression
EXP
Dieldrin results in decreased expression of MGST2 mRNA
CTD
PMID:19440498
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661
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Mir24-2
microRNA 24-2
increases expression
ISO
Dieldrin results in increased expression of MIR24-2 mRNA
CTD
PMID:31068361
NCBI chr19:40,859,455...40,859,562
G
Mki67
marker of proliferation Ki-67
affects expression
EXP
Dieldrin affects the expression of MKI67 mRNA
CTD
PMID:22546817
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
G
Mmd
monocyte to macrophage differentiation-associated
increases expression
EXP
Dieldrin results in increased expression of MMD mRNA
CTD
PMID:23153324
NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609
G
Mmp9
matrix metallopeptidase 9
increases expression
EXP
Dieldrin results in increased expression of MMP9 mRNA
CTD
PMID:23153324
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
G
Moap1
modulator of apoptosis 1
affects expression
EXP
Dieldrin affects the expression of MOAP1 mRNA
CTD
PMID:22546817
NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:127,613,488...127,669,324
G
Mrtfa
myocardin related transcription factor A
affects expression
EXP
Dieldrin affects the expression of MRTFA mRNA
CTD
PMID:22546817
NCBI chr 7:114,424,481...114,594,594
Ensembl chr 7:114,424,481...114,594,594
G
Msh2
mutS homolog 2
affects expression
EXP
Dieldrin affects the expression of MSH2 mRNA
CTD
PMID:22546817
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
G
Mtch1
mitochondrial carrier 1
affects expression
EXP
Dieldrin affects the expression of MTCH1 mRNA
CTD
PMID:22546817
NCBI chr20:7,391,558...7,415,291
Ensembl chr20:7,391,565...7,415,042
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Mtor
mechanistic target of rapamycin kinase
increases phosphorylation
ISO
Dieldrin results in increased phosphorylation of MTOR protein
CTD
PMID:31068361
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
G
Mx1
MX dynamin like GTPase 1
multiple interactions decreases expression
ISO EXP
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA] Dieldrin results in decreased expression of MX1 mRNA
CTD
PMID:34051100
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
G
Mx2
MX dynamin like GTPase 2
decreases expression
EXP
Dieldrin results in decreased expression of MX2 mRNA
CTD
PMID:34051100
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:50,375,191...50,402,478
G
Myadm
myeloid-associated differentiation marker
increases expression
ISO
Dieldrin results in increased expression of MYADM mRNA
CTD
PMID:31068361
NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710
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Myc
MYC proto-oncogene, bHLH transcription factor
affects expression
EXP
Dieldrin affects the expression of MYC mRNA
CTD
PMID:22546817
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
G
Mycn
MYCN proto-oncogene, bHLH transcription factor
affects expression
EXP
Dieldrin affects the expression of MYCN mRNA
CTD
PMID:22546817
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508
G
Myf6
myogenic factor 6
affects methylation
ISO
Dieldrin affects the methylation of MYF6 gene
CTD
PMID:38995845
NCBI chr 7:44,699,469...44,701,313
Ensembl chr 7:44,699,469...44,701,313
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Myo3b
myosin IIIB
affects methylation
ISO
Dieldrin affects the methylation of MYO3B gene
CTD
PMID:38995845
NCBI chr 3:75,228,017...75,636,272
Ensembl chr 3:75,228,017...75,636,272
G
Nacc1
nucleus accumbens associated 1
affects expression
EXP
Dieldrin affects the expression of NACC1 mRNA
CTD
PMID:22546817
NCBI chr19:23,468,688...23,486,528
Ensembl chr19:40,373,449...40,391,347
G
Nags
N-acetylglutamate synthase
decreases expression
EXP
Dieldrin results in decreased expression of NAGS mRNA
CTD
PMID:23153324
NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,598,220...87,602,650
G
Nampt
nicotinamide phosphoribosyltransferase
affects expression
EXP
Dieldrin affects the expression of NAMPT mRNA
CTD
PMID:22546817
NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544
G
Nanog
Nanog homeobox
multiple interactions
ISO
Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of NANOG mRNA]
CTD
PMID:32949729
NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061
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Ndc80
NDC80 kinetochore complex component
affects expression
EXP
Dieldrin affects the expression of NDC80 mRNA
CTD
PMID:22546817
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
G
Ndn
necdin, MAGE family member
affects expression
EXP
Dieldrin affects the expression of NDN mRNA
CTD
PMID:22546817
NCBI chr 1:125,261,059...125,262,658
Ensembl chr 1:125,260,997...125,262,785
G
Nectin1
nectin cell adhesion molecule 1
affects methylation
ISO
Dieldrin affects the methylation of NECTIN1 gene
CTD
PMID:38995845
NCBI chr 8:52,998,662...53,061,745
Ensembl chr 8:52,998,662...53,086,664
G
Nedd8
NEDD8 ubiquitin like modifier
affects expression
EXP
Dieldrin affects the expression of NEDD8 mRNA
CTD
PMID:22546817
NCBI chr15:29,153,556...29,165,575
Ensembl chr15:33,123,505...33,135,522
G
Nefh
neurofilament heavy chain
decreases expression
EXP
Dieldrin results in decreased expression of NEFH mRNA
CTD
PMID:18812211
NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417
G
Nefl
neurofilament light chain
increases expression
EXP
Dieldrin results in increased expression of NEFL mRNA
CTD
PMID:18812211
NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515
G
Nefm
neurofilament medium chain
increases expression
EXP
Dieldrin results in increased expression of NEFM mRNA
CTD
PMID:18812211
NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163
G
Nek3
NIMA-related kinase 3
affects expression
EXP
Dieldrin affects the expression of NEK3 mRNA
CTD
PMID:22546817
NCBI chr16:69,867,020...69,892,477
Ensembl chr16:76,569,496...76,594,921
G
Nfatc2
nuclear factor of activated T-cells 2
decreases phosphorylation
ISO
Dieldrin results in decreased phosphorylation of NFATC2 protein
CTD
PMID:31068361
NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380
G
Nfkb1
nuclear factor kappa B subunit 1
affects expression
EXP
Dieldrin affects the expression of NFKB1 mRNA
CTD
PMID:22546817
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
G
Nfkbia
NFKB inhibitor alpha
increases expression
ISO
Dieldrin results in increased expression of NFKBIA mRNA
CTD
PMID:31068361
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
G
Nfkbid
NFKB inhibitor delta
increases expression
ISO
Dieldrin results in increased expression of NFKBID mRNA
CTD
PMID:31068361
NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861
G
Nfkbiz
NFKB inhibitor zeta
increases expression
ISO
Dieldrin results in increased expression of NFKBIZ mRNA
CTD
PMID:31068361
NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767
G
Nfu1
NFU1 iron-sulfur cluster scaffold
affects expression
EXP
Dieldrin affects the expression of NFU1 mRNA
CTD
PMID:22546817
NCBI chr 4:121,016,316...121,036,925
Ensembl chr 4:121,016,393...121,037,493
G
Nfyc
nuclear transcription factor Y subunit gamma
affects expression
EXP
Dieldrin affects the expression of NFYC mRNA
CTD
PMID:22546817
NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:139,622,020...139,679,884
G
Ngf
nerve growth factor
multiple interactions
ISO EXP
[Dieldrin co-treated with NGF protein] results in increased expression of SLC1A5 mRNA; [Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA Dieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]
CTD
PMID:20600679 PMID:28385489
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
G
Nnt
nicotinamide nucleotide transhydrogenase
decreases expression
EXP
Dieldrin results in decreased expression of NNT mRNA
CTD
PMID:23153324
NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:53,144,160...53,237,310
G
Nop2
NOP2 nucleolar protein
affects expression
EXP
Dieldrin affects the expression of NOP2 mRNA
CTD
PMID:22546817
NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:159,618,966...159,630,697
G
Notch1
notch receptor 1
affects expression
EXP
Dieldrin affects the expression of NOTCH1 mRNA
CTD
PMID:22546817
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
G
Notch2
notch receptor 2
affects expression decreases expression
EXP ISO
Dieldrin affects the expression of NOTCH2 mRNA Dieldrin results in decreased expression of NOTCH2 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823
G
Notch3
notch receptor 3
decreases expression
ISO
Dieldrin results in decreased expression of NOTCH3 mRNA
CTD
PMID:31068361
NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,784,272...11,834,778
G
Nox1
NADPH oxidase 1
multiple interactions
EXP
[Hexachlorocyclohexane co-treated with Dieldrin] results in decreased expression of NOX1 protein
CTD
PMID:30240590
NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520
G
Npas4
neuronal PAS domain protein 4
increases expression
ISO
Dieldrin results in increased expression of NPAS4 mRNA
CTD
PMID:31068361
NCBI chr 1:211,710,640...211,728,038
Ensembl chr 1:211,711,338...211,716,102
G
Npm1
nucleophosmin 1
affects expression
EXP
Dieldrin affects the expression of NPM1 mRNA
CTD
PMID:22546817
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
G
Nprl2
NPR2-like, GATOR1 complex subunit
increases response to substance
ISO
NPRL2 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:117,094,441...117,097,637
G
Nprl3
NPR3-like, GATOR1 complex subunit
increases response to substance
ISO
NPRL3 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,859,789...15,902,332
G
Npy
neuropeptide Y
increases expression
EXP
Dieldrin results in increased expression of NPY mRNA
CTD
PMID:20682304
NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity multiple interactions
ISO EXP
Dieldrin results in increased activity of NR1I2 protein Dieldrin binds to and results in increased activity of NR1I2 protein; NR1I2 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA] [DDT co-treated with Dieldrin] results in increased activity of NR1I2 protein; Dieldrin binds to and results in increased activity of NR1I2 protein; Dieldrin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA] [Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA
CTD
PMID:12049174 PMID:12417264 PMID:15548381 PMID:16054614 PMID:21115097 PMID:24615737 PMID:25028461 PMID:25680588 PMID:32435917 More...
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
multiple interactions increases activity
ISO
NR1I3 protein affects the reaction [Dieldrin results in increased expression of AOX1 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA] Dieldrin results in increased activity of NR1I3 protein
CTD
PMID:12049174 PMID:28927721 PMID:32435917
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
G
Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
Dieldrin results in increased expression of NR4A1 mRNA
CTD
PMID:31068361
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
G
Nr4a2
nuclear receptor subfamily 4, group A, member 2
affects methylation increases expression
ISO
Dieldrin affects the methylation of NR4A2 gene Dieldrin results in increased expression of NR4A2 mRNA
CTD
PMID:30859219 PMID:31068361 PMID:38995845
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
G
Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
Dieldrin results in increased expression of NR4A3 mRNA
CTD
PMID:31068361
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
G
Nradd
neurotrophin receptor associated death domain
affects expression
EXP
Dieldrin affects the expression of NRADD mRNA
CTD
PMID:22546817
NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:119,477,240...119,481,214
G
Nrap
nebulin-related anchoring protein
affects methylation
ISO
Dieldrin affects the methylation of NRAP gene
CTD
PMID:38995845
NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:265,355,327...265,432,950
G
Nsmaf
neutral sphingomyelinase activation associated factor
affects expression
EXP
Dieldrin affects the expression of NSMAF mRNA
CTD
PMID:22546817
NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:24,315,319...24,375,355
G
Nt5dc2
5'-nucleotidase domain containing 2
increases expression
EXP
Dieldrin results in increased expression of NT5DC2 mRNA
CTD
PMID:23153324
NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,328,523...6,336,980
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Ntf4
neurotrophin 4
increases expression
EXP
Dieldrin results in increased expression of NTF4 mRNA
CTD
PMID:19130878
NCBI chr 1:105,030,035...105,032,866
Ensembl chr 1:105,029,764...105,034,038
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Ntn1
netrin 1
affects expression
EXP
Dieldrin affects the expression of NTN1 mRNA
CTD
PMID:22546817
NCBI chr10:53,398,852...53,597,595
Ensembl chr10:53,398,852...53,584,060
G
Ntrk1
neurotrophic receptor tyrosine kinase 1
increases expression multiple interactions
EXP ISO
Dieldrin results in increased expression of NTRK1 mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA
CTD
PMID:19130878 PMID:28263720
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
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Ntrk2
neurotrophic receptor tyrosine kinase 2
affects expression multiple interactions
EXP ISO
Dieldrin affects the expression of NTRK2 mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA
CTD
PMID:19130878 PMID:28263720
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
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Ntrk3
neurotrophic receptor tyrosine kinase 3
decreases expression
EXP
Dieldrin results in decreased expression of NTRK3 mRNA
CTD
PMID:19130878
NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004
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Nts
neurotensin
increases expression
EXP
Dieldrin results in increased expression of NTS mRNA
CTD
PMID:20682304
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
G
Nuf2
NUF2 component of NDC80 kinetochore complex
affects expression
EXP
Dieldrin affects the expression of NUF2 mRNA
CTD
PMID:22546817
NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598
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Oasl
2'-5'-oligoadenylate synthetase-like
decreases expression
EXP
Dieldrin results in decreased expression of OASL mRNA
CTD
PMID:34051100
NCBI chr12:41,682,900...41,695,641
Ensembl chr12:47,343,551...47,356,483
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Opa1
OPA1, mitochondrial dynamin like GTPase
affects expression
EXP
Dieldrin affects the expression of OPA1 mRNA
CTD
PMID:22546817
NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
G
Otx2
orthodenticle homeobox 2
multiple interactions
ISO
Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of OTX2 mRNA]
CTD
PMID:32949729
NCBI chr15:24,422,876...24,432,709
Ensembl chr15:24,422,876...24,432,472
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P2rx4
purinergic receptor P2X 4
decreases expression
EXP
Dieldrin results in decreased expression of P2RX4 mRNA
CTD
PMID:23153324
NCBI chr12:39,505,438...39,523,349
Ensembl chr12:39,505,438...39,523,094
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Palm
paralemmin
affects methylation
ISO
Dieldrin affects the methylation of PALM gene
CTD
PMID:38995845
NCBI chr 7:9,886,634...9,912,389
Ensembl chr 7:10,537,277...10,563,007
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Pard6a
par-6 family cell polarity regulator alpha
affects expression
EXP
Dieldrin affects the expression of PARD6A mRNA
CTD
PMID:22546817
NCBI chr19:50,499,420...50,502,301
Ensembl chr19:50,499,442...50,502,674
G
Parm1
prostate androgen-regulated mucin-like protein 1
affects expression
EXP
Dieldrin affects the expression of PARM1 mRNA
CTD
PMID:22546817
NCBI chr14:16,752,541...16,861,570
Ensembl chr14:16,752,541...16,881,138
G
Parp1
poly (ADP-ribose) polymerase 1
increases cleavage multiple interactions
EXP
Dieldrin results in increased cleavage of PARP1 protein benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of PARP1 protein]
CTD
PMID:15183012
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pax2
paired box 2
affects methylation
ISO
Dieldrin affects the methylation of PAX2 gene
CTD
PMID:38995845
NCBI chr 1:253,555,447...253,646,623
Ensembl chr 1:253,555,418...253,645,438
G
Pax6
paired box 6
multiple interactions
ISO
Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of PAX6 mRNA]
CTD
PMID:32949729
NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763
G
Pbk
PDZ binding kinase
increases expression
EXP
Dieldrin results in increased expression of PBK mRNA
CTD
PMID:23153324
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:44,198,544...44,209,570
G
Pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
affects methylation
ISO
Dieldrin affects the methylation of PCMTD1 gene
CTD
PMID:38995845
NCBI chr 5:12,284,711...12,355,680
Ensembl chr 5:17,071,629...17,142,010
G
Pcna
proliferating cell nuclear antigen
increases expression
EXP
Dieldrin results in increased expression of PCNA mRNA
CTD
PMID:23153324
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
G
Pdcd2
programmed cell death 2
affects expression
EXP
Dieldrin affects the expression of PDCD2 mRNA
CTD
PMID:22546817
NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:65,158,034...65,163,524
G
Pdcd6
programmed cell death 6
affects expression
EXP
Dieldrin affects the expression of PDCD6 mRNA
CTD
PMID:22546817
NCBI chr 1:30,795,105...30,810,771
Ensembl chr 1:30,795,040...30,810,773
G
Pdgfa
platelet derived growth factor subunit A
affects expression
EXP
Dieldrin affects the expression of PDGFA mRNA
CTD
PMID:22546817
NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322
G
Pdgfra
platelet derived growth factor receptor alpha
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRA mRNA
CTD
PMID:19422813
NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516
G
Pdgfrb
platelet derived growth factor receptor beta
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
G
Pdk1
pyruvate dehydrogenase kinase 1
decreases expression
EXP
Dieldrin results in decreased expression of PDK1 mRNA
CTD
PMID:23153324
NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
G
Pdk4
pyruvate dehydrogenase kinase 4
decreases expression
EXP
Dieldrin results in decreased expression of PDK4 mRNA
CTD
PMID:23153324
NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381
G
Penk
proenkephalin
decreases expression
EXP
Dieldrin results in decreased expression of PENK mRNA
CTD
PMID:20682304
NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705
G
Pgf
placental growth factor
affects expression
EXP
Dieldrin affects the expression of PGF mRNA
CTD
PMID:22546817
NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747
G
Pgr
progesterone receptor
increases expression multiple interactions
EXP ISO
Dieldrin results in increased expression of PGR mRNA Dieldrin inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]
CTD
PMID:10774817 PMID:26022396
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
G
Phlda1
pleckstrin homology-like domain, family A, member 1
affects expression increases expression
EXP ISO
Dieldrin affects the expression of PHLDA1 mRNA Dieldrin results in increased expression of PHLDA1 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
G
Pidd1
p53-induced death domain protein 1
affects expression
EXP
Dieldrin affects the expression of PIDD1 mRNA
CTD
PMID:22546817
NCBI chr 1:205,966,392...205,972,359
Ensembl chr 1:205,966,392...205,971,600
G
Pla2g7
phospholipase A2 group VII
affects methylation
ISO
Dieldrin affects the methylation of PLA2G7 gene
CTD
PMID:38995845
NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747
G
Plagl2
PLAG1 like zinc finger 2
affects expression
EXP
Dieldrin affects the expression of PLAGL2 mRNA
CTD
PMID:22546817
NCBI chr 3:141,695,322...141,708,516
Ensembl chr 3:162,155,554...162,168,748
G
Plcb1
phospholipase C beta 1
affects expression
EXP
Dieldrin affects the expression of PLCB1 mRNA
CTD
PMID:22546817
NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646
G
Plekhf1
pleckstrin homology and FYVE domain containing 1
affects expression
EXP
Dieldrin affects the expression of PLEKHF1 mRNA
CTD
PMID:22546817
NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:100,027,056...100,053,452
G
Plk1
polo-like kinase 1
affects expression
EXP
Dieldrin affects the expression of PLK1 mRNA
CTD
PMID:22546817
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
G
Plk2
polo-like kinase 2
affects expression
EXP
Dieldrin affects the expression of PLK2 mRNA
CTD
PMID:22546817
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296
G
Plk4
polo-like kinase 4
affects expression
EXP
Dieldrin affects the expression of PLK4 mRNA
CTD
PMID:22546817
NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892
G
Plpp3
phospholipid phosphatase 3
decreases expression
EXP
Dieldrin results in decreased expression of PLPP3 mRNA
CTD
PMID:23153324
NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
G
Plxnd1
plexin D1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA
CTD
PMID:28263720
NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:150,675,377...150,715,566
G
Pmp22
peripheral myelin protein 22
affects expression
EXP
Dieldrin affects the expression of PMP22 mRNA
CTD
PMID:22546817
NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940
G
Pnpla6
patatin-like phospholipase domain containing 6
decreases expression
ISO
Dieldrin results in decreased expression of PNPLA6 mRNA
CTD
PMID:31068361
NCBI chr12:6,372,284...6,401,632
Ensembl chr12:6,372,293...6,401,631
G
Pnrc1
proline-rich nuclear receptor coactivator 1
increases expression
ISO
Dieldrin results in increased expression of PNRC1 mRNA
CTD
PMID:31068361
NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:52,443,400...52,446,491
G
Pomgnt2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
affects methylation
ISO
Dieldrin affects the methylation of POMGNT2 gene
CTD
PMID:38995845
NCBI chr 8:130,522,607...130,538,273
Ensembl chr 8:130,521,459...130,571,943
G
Pon1
paraoxonase 1
multiple interactions
EXP
[Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein] results in increased expression of PON1 mRNA
CTD
PMID:24615737
NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924
G
Pou5f1
POU class 5 homeobox 1
multiple interactions
ISO
Dieldrin promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of POU5F1 mRNA]
CTD
PMID:32949729
NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598
G
Ppp1r10
protein phosphatase 1, regulatory subunit 10
increases expression
ISO
Dieldrin results in increased expression of PPP1R10 mRNA
CTD
PMID:31068361
NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418
G
Ppp1r13b
protein phosphatase 1, regulatory subunit 13B
affects expression
EXP
Dieldrin affects the expression of PPP1R13B mRNA
CTD
PMID:22546817
NCBI chr 6:130,890,682...130,963,845
Ensembl chr 6:136,711,834...136,785,113
G
Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
Dieldrin results in increased expression of PPP1R15A mRNA
CTD
PMID:31068361
NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774
G
Ppp1r16b
protein phosphatase 1, regulatory subunit 16B
affects methylation
ISO
Dieldrin affects the methylation of PPP1R16B gene
CTD
PMID:38995845
NCBI chr 3:167,743,518...167,839,511
Ensembl chr 3:167,743,952...167,839,242
G
Ppp2r5d
protein phosphatase 2, regulatory subunit B', delta
affects methylation
ISO
Dieldrin affects the methylation of PPP2R5D gene
CTD
PMID:38995845
NCBI chr 9:21,767,963...21,797,997
Ensembl chr 9:21,767,688...21,797,996
G
Prdm16
PR/SET domain 16
affects methylation
ISO
Dieldrin affects the methylation of PRDM16 gene
CTD
PMID:38995845
NCBI chr 5:170,162,275...170,486,371
Ensembl chr 5:170,162,275...170,485,804
G
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
affects methylation
ISO
Dieldrin affects the methylation of PREX1 gene
CTD
PMID:38995845
NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764
G
Prkag2
protein kinase AMP-activated non-catalytic subunit gamma 2
affects methylation
ISO
Dieldrin affects the methylation of PRKAG2 gene
CTD
PMID:38995845
NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939
G
Prkca
protein kinase C, alpha
affects methylation
ISO
Dieldrin affects the methylation of PRKCA gene
CTD
PMID:38995845
NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
G
Prkcd
protein kinase C, delta
multiple interactions increases activity affects expression
ISO EXP
BCL2 protein inhibits the reaction [Dieldrin results in increased activity of PRKCD protein] benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of and results in increased activity of PRKCD protein]; Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]; Dieldrin results in increased cleavage of and results in increased activity of PRKCD protein; Dieldrin results in increased phosphorylation of and results in increased cleavage of PRKCD protein; FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; FYN protein promotes the reaction [Dieldrin results in increased phosphorylation of PRKCD protein] Dieldrin affects the expression of PRKCD mRNA
CTD
PMID:12831855 PMID:15033812 PMID:21801747 PMID:22546817
NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839
G
Prkce
protein kinase C, epsilon
affects methylation
ISO
Dieldrin affects the methylation of PRKCE gene
CTD
PMID:38995845
NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288
G
Prkn
parkin RBR E3 ubiquitin protein ligase
increases response to substance
ISO
PARK2 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
G
Prl
prolactin
multiple interactions increases secretion
EXP
Nifedipine inhibits the reaction [Dieldrin results in increased secretion of PRL protein]
CTD
PMID:15811834 PMID:17174995
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
G
Prx
periaxin
decreases expression
ISO
Dieldrin results in decreased expression of PRX mRNA
CTD
PMID:31068361
NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:91,911,999...91,937,235
G
Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Dieldrin affects the expression of PSMD1 mRNA
CTD
PMID:22546817
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:94,157,971...94,233,218
G
Ptbp1
polypyrimidine tract binding protein 1
affects methylation
ISO
Dieldrin affects the methylation of PTBP1 gene
CTD
PMID:38995845
NCBI chr 7:10,493,199...10,502,957
Ensembl chr 7:10,493,200...10,502,957
G
Pten
phosphatase and tensin homolog
increases response to substance
ISO
PTEN gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
G
Ptger4
prostaglandin E receptor 4
increases expression
ISO
Dieldrin results in increased expression of PTGER4 mRNA
CTD
PMID:31068361
NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135
G
Ptk7
protein tyrosine kinase 7
affects methylation
ISO
Dieldrin affects the methylation of PTK7 gene
CTD
PMID:38995845
NCBI chr 9:21,849,756...21,916,077
Ensembl chr 9:21,849,801...21,916,078
G
Ptn
pleiotrophin
affects expression
EXP
Dieldrin affects the expression of PTN mRNA
CTD
PMID:22546817
NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482
G
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
affects methylation
ISO
Dieldrin affects the methylation of PTPN14 gene
CTD
PMID:38995845
NCBI chr13:101,268,258...101,420,508
Ensembl chr13:103,799,494...103,951,708
G
Pttg1
PTTG1 regulator of sister chromatid separation, securin
increases expression affects expression
EXP
Dieldrin results in increased expression of PTTG1 mRNA Dieldrin affects the expression of PTTG1 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:28,394,814...28,406,309
G
Pxn
paxillin
increases response to substance
ISO
PXN gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr12:46,721,546...46,768,706
Ensembl chr12:46,721,546...46,768,697
G
Pycard
PYD and CARD domain containing
affects expression
EXP
Dieldrin affects the expression of PYCARD mRNA
CTD
PMID:22546817
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
G
Rabep1
rabaptin, RAB GTPase binding effector protein 1
affects expression
EXP
Dieldrin affects the expression of RABEP1 mRNA
CTD
PMID:22546817
NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177
G
Rad1
RAD1 checkpoint DNA exonuclease
affects expression
EXP
Dieldrin affects the expression of RAD1 mRNA
CTD
PMID:22546817
NCBI chr 2:61,188,755...61,196,868
Ensembl chr 2:61,188,727...61,196,867
G
Raf1
Raf-1 proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Dieldrin results in increased phosphorylation of and results in increased activity of RAF1 protein
CTD
PMID:15888667
NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813
G
Rai1
retinoic acid induced 1
affects methylation
ISO
Dieldrin affects the methylation of RAI1 gene
CTD
PMID:38995845
NCBI chr10:45,412,748...45,507,747
Ensembl chr10:45,447,427...45,507,747
G
Rap1a
RAP1A, member of RAS oncogene family
affects expression
EXP
Dieldrin affects the expression of RAP1A mRNA
CTD
PMID:22546817
NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:195,896,971...195,974,808
G
Rara
retinoic acid receptor, alpha
affects expression
EXP
Dieldrin affects the expression of RARA mRNA
CTD
PMID:22546817
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
G
Rarb
retinoic acid receptor, beta
increases expression
ISO
Dieldrin results in increased expression of RARB mRNA
CTD
PMID:15589975
NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
G
Rarg
retinoic acid receptor, gamma
increases expression increases activity
ISO
Dieldrin results in increased expression of RARG mRNA Dieldrin results in increased activity of RARG protein
CTD
PMID:15589975 PMID:30639747
NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889
G
Rb1
RB transcriptional corepressor 1
affects expression
EXP
Dieldrin affects the expression of RB1 mRNA
CTD
PMID:22546817
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
G
Rbfox1
RNA binding fox-1 homolog 1
affects methylation
ISO
Dieldrin affects the methylation of RBFOX1 gene
CTD
PMID:38995845
NCBI chr10:8,658,809...10,754,648
Ensembl chr10:8,658,809...10,754,706
G
Rbfox3
RNA binding fox-1 homolog 3
affects methylation
ISO
Dieldrin affects the methylation of RBFOX3 gene
CTD
PMID:38995845
NCBI chr10:103,720,355...104,157,277
Ensembl chr10:104,218,940...104,551,945
G
Rbl2
RB transcriptional corepressor like 2
affects expression decreases expression
EXP
Dieldrin affects the expression of RBL2 mRNA Dieldrin results in decreased expression of RBL2 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr19:32,049,690...32,096,467
Ensembl chr19:32,049,691...32,096,411
G
Ret
ret proto-oncogene
affects expression multiple interactions
EXP ISO
Dieldrin affects the expression of RET mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA
CTD
PMID:22546817 PMID:28263720
NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556
G
Rfc4
replication factor C subunit 4
increases expression
EXP
Dieldrin results in increased expression of RFC4 mRNA
CTD
PMID:23153324
NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730
G
Rgma
repulsive guidance molecule BMP co-receptor a
affects methylation
ISO
Dieldrin affects the methylation of RGMA gene
CTD
PMID:38995845
NCBI chr 1:136,538,782...136,582,763
Ensembl chr 1:136,538,759...136,582,763
G
Rgs2
regulator of G-protein signaling 2
affects expression increases expression
EXP ISO
Dieldrin affects the expression of RGS2 mRNA Dieldrin results in increased expression of RGS2 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697
G
Rhoq
ras homolog family member Q
affects methylation
ISO
Dieldrin affects the methylation of RHOQ gene
CTD
PMID:38995845
NCBI chr 6:7,613,632...7,652,047
Ensembl chr 1:115,757,909...115,759,467
G
Rig1
RNA sensor RIG-1
decreases expression
EXP
Dieldrin results in decreased expression of RIGI mRNA
CTD
PMID:34051100
NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995
G
Ripk2
receptor-interacting serine-threonine kinase 2
affects expression
EXP
Dieldrin affects the expression of RIPK2 mRNA
CTD
PMID:22546817
NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663
G
Rnasel
ribonuclease L
decreases expression
EXP
Dieldrin results in decreased expression of RNASEL mRNA
CTD
PMID:34051100
NCBI chr13:68,446,641...68,460,804
Ensembl chr13:68,446,882...68,459,557
G
Rnd3
Rho family GTPase 3
affects expression
EXP
Dieldrin affects the expression of RND3 mRNA
CTD
PMID:22546817
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:55,980,355...55,998,536
G
Rnf34
ring finger protein 34
affects expression
EXP
Dieldrin affects the expression of RNF34 mRNA
CTD
PMID:22546817
NCBI chr12:33,703,655...33,724,606
Ensembl chr12:39,355,578...39,385,340
G
Rnf7
ring finger protein 7
decreases response to substance
ISO
RNF7 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 8:105,918,395...105,927,643
Ensembl chr 8:105,918,395...105,927,405
G
Rtn4
reticulon 4
affects expression
EXP
Dieldrin affects the expression of RTN4 mRNA
CTD
PMID:22546817
NCBI chr14:107,651,001...107,698,610
Ensembl chr14:107,650,732...107,698,611
G
Rxra
retinoid X receptor alpha
multiple interactions affects methylation
EXP ISO
[Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein] results in increased expression of PON1 mRNA Dieldrin affects the methylation of RXRA gene
CTD
PMID:24615737 PMID:38995845
NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417
G
S100a6
S100 calcium binding protein A6
affects expression
EXP
Dieldrin affects the expression of S100A6 mRNA
CTD
PMID:22546817
NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762
G
Sall1
spalt-like transcription factor 1
decreases expression
EXP
Dieldrin results in decreased expression of SALL1 mRNA
CTD
PMID:23153324
NCBI chr19:34,179,316...34,196,278
Ensembl chr19:34,181,078...34,196,278
G
Sart1
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
affects expression
EXP
Dieldrin affects the expression of SART1 mRNA
CTD
PMID:22546817
NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486
G
Sbf1
SET binding factor 1
decreases expression
ISO
Dieldrin results in decreased expression of SBF1 mRNA
CTD
PMID:31068361
NCBI chr 7:122,237,968...122,264,591
Ensembl chr 7:122,237,968...122,264,531
G
Sbno2
strawberry notch homolog 2
affects methylation
ISO
Dieldrin affects the methylation of SBNO2 gene
CTD
PMID:38995845
NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:10,253,248...10,300,176
G
Scn2a
sodium voltage-gated channel alpha subunit 2
affects expression
EXP
Dieldrin affects the expression of SCN2A mRNA
CTD
PMID:22546817
NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:70,710,954...70,845,279
G
Septin7
septin 7
affects expression
EXP
Dieldrin affects the expression of SEPTIN7 mRNA
CTD
PMID:22546817
NCBI chr 8:31,995,597...32,059,069
Ensembl chr 8:31,995,005...32,059,072
G
Serinc3
serine incorporator 3
affects expression
EXP
Dieldrin affects the expression of SERINC3 mRNA
CTD
PMID:22546817
NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765
G
Serpine1
serpin family E member 1
increases expression
ISO
Dieldrin results in increased expression of SERPINE1 mRNA
CTD
PMID:31068361
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
G
Setd1b
SET domain containing 1B, histone lysine methyltransferase
affects methylation
ISO
Dieldrin affects the methylation of SETD1B gene
CTD
PMID:38995845
NCBI chr12:33,395,963...33,421,671
Ensembl chr12:39,058,262...39,082,566
G
Sf1
splicing factor 1
affects expression
EXP
Dieldrin affects the expression of SF1 mRNA
CTD
PMID:22546817
NCBI chr 1:213,090,256...213,112,688
Ensembl chr 1:213,099,260...213,113,590
G
Sgk1
serum/glucocorticoid regulated kinase 1
affects expression increases expression
EXP ISO
Dieldrin affects the expression of SGK1 mRNA Dieldrin results in increased expression of SGK1 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:24,799,396...24,807,231
G
Sgpl1
sphingosine-1-phosphate lyase 1
affects expression
EXP
Dieldrin affects the expression of SGPL1 mRNA
CTD
PMID:22546817
NCBI chr20:29,590,652...29,637,064
Ensembl chr20:29,592,721...29,667,753
G
Sgpp1
sphingosine-1-phosphate phosphatase 1
affects expression
EXP
Dieldrin affects the expression of SGPP1 mRNA
CTD
PMID:22546817
NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259
G
Sh3pxd2a
SH3 and PX domains 2A
affects methylation
ISO
Dieldrin affects the methylation of SH3PXD2A gene
CTD
PMID:38995845
NCBI chr 1:256,094,991...256,301,120
Ensembl chr 1:256,094,991...256,300,967
G
Shbg
sex hormone binding globulin
multiple interactions
EXP
Dieldrin inhibits the reaction [Dihydrotestosterone binds to SHBG protein]
CTD
PMID:9171990
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760
G
Shld2
shieldin complex subunit 2
decreases expression
EXP
Dieldrin results in decreased expression of SHLD2 mRNA
CTD
PMID:23153324
NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,553,854...9,588,510
G
Sik1
salt-inducible kinase 1
increases expression
ISO
Dieldrin results in increased expression of SIK1 mRNA
CTD
PMID:31068361
NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698
G
Sipa1
signal-induced proliferation-associated 1
affects expression
EXP
Dieldrin affects the expression of SIPA1 mRNA
CTD
PMID:22546817
NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:212,367,867...212,377,497
G
Sipa1l3
signal-induced proliferation-associated 1 like 3
affects methylation
ISO
Dieldrin affects the methylation of SIPA1L3 gene
CTD
PMID:38995845
NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:93,746,192...93,831,268
G
Sirt2
sirtuin 2
affects expression
EXP
Dieldrin affects the expression of SIRT2 mRNA
CTD
PMID:22546817
NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499
G
Slc10a1
solute carrier family 10 member 1
decreases expression
ISO EXP
Dieldrin results in decreased expression of SLC10A1 mRNA
CTD
PMID:23153324 PMID:24464585
NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944
G
Slc12a4
solute carrier family 12 member 4
affects expression
EXP
Dieldrin affects the expression of SLC12A4 mRNA
CTD
PMID:22546817
NCBI chr19:50,748,268...50,770,217
Ensembl chr19:50,748,279...50,770,259
G
Slc13a3
solute carrier family 13 member 3
decreases expression
EXP
Dieldrin results in decreased expression of SLC13A3 mRNA
CTD
PMID:23153324
NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:174,561,168...174,623,895
G
Slc16a1
solute carrier family 16 member 1
decreases expression
EXP
Dieldrin results in decreased expression of SLC16A1 mRNA
CTD
PMID:23153324
NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
G
Slc16a11
solute carrier family 16, member 11
decreases expression
EXP
Dieldrin results in decreased expression of SLC16A11 mRNA
CTD
PMID:23153324
NCBI chr10:54,929,129...54,933,021
Ensembl chr10:55,427,903...55,431,678
G
Slc16a2
solute carrier family 16 member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC16A2 mRNA
CTD
PMID:23153324
NCBI chr X:72,791,096...72,914,299
Ensembl chr X:72,781,876...72,914,498
G
Slc16a4
solute carrier family 16, member 4
decreases expression
EXP
Dieldrin results in decreased expression of SLC16A4 mRNA
CTD
PMID:23153324
NCBI chr 2:197,593,738...197,621,569
Ensembl chr 2:197,599,295...197,621,562
G
Slc16a7
solute carrier family 16 member 7
decreases expression
EXP
Dieldrin results in decreased expression of SLC16A7 mRNA
CTD
PMID:23153324
NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386
G
Slc17a2
solute carrier family 17, member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC17A2 mRNA
CTD
PMID:23153324
NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,748,195...41,764,180
G
Slc17a3
solute carrier family 17 member 3
decreases expression
EXP
Dieldrin results in decreased expression of SLC17A3 mRNA
CTD
PMID:23153324
NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,698,680...41,723,329
G
Slc17a5
solute carrier family 17 member 5
decreases expression
EXP
Dieldrin results in decreased expression of SLC17A5 mRNA
CTD
PMID:23153324
NCBI chr 8:79,394,416...79,429,387
Ensembl chr 8:88,274,721...88,309,664
G
Slc18a1
solute carrier family 18 member A1
decreases expression
EXP
Dieldrin results in decreased expression of SLC18A1 mRNA
CTD
PMID:18812211 PMID:18835401
NCBI chr16:25,408,485...25,453,786
Ensembl chr16:25,420,243...25,453,786
G
Slc18a2
solute carrier family 18 member A2
increases expression
ISO
Dieldrin results in increased expression of SLC18A2 mRNA; Dieldrin results in increased expression of SLC18A2 protein
CTD
PMID:16809432
NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231
G
Slc18a3
solute carrier family 18 member A3
affects expression
EXP
Dieldrin affects the expression of SLC18A3 mRNA
CTD
PMID:18812211
NCBI chr16:7,719,953...7,722,814
G
Slc19a2
solute carrier family 19 member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC19A2 mRNA
CTD
PMID:23153324
NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315
G
Slc1a5
solute carrier family 1 member 5
multiple interactions
ISO
[Dieldrin co-treated with NGF protein] results in increased expression of SLC1A5 mRNA
CTD
PMID:20600679
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
G
Slc22a1
solute carrier family 22 member 1
decreases activity
ISO
Dieldrin results in decreased activity of SLC22A1 protein
CTD
PMID:24464585
NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
G
Slc22a23
solute carrier family 22, member 23
decreases expression
EXP
Dieldrin results in decreased expression of SLC22A23 mRNA
CTD
PMID:23153324
NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,749,445...30,915,139
G
Slc29a1
solute carrier family 29 member 1
decreases expression
EXP
Dieldrin results in decreased expression of SLC29A1 mRNA
CTD
PMID:23153324
NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
G
Slc2a2
solute carrier family 2 member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC2A2 mRNA
CTD
PMID:23153324
NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467
G
Slc31a2
solute carrier family 31 member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC31A2 mRNA
CTD
PMID:23153324
NCBI chr 5:75,738,008...75,748,542
Ensembl chr 5:80,753,618...80,764,123
G
Slc34a2
solute carrier family 34 member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC34A2 mRNA
CTD
PMID:23153324
NCBI chr14:62,123,313...62,153,020
Ensembl chr14:62,123,316...62,143,360
G
Slc38a1
solute carrier family 38, member 1
increases expression
EXP
Dieldrin results in increased expression of SLC38A1 mRNA
CTD
PMID:23153324
NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:129,617,387...129,681,778
G
Slc5a6
solute carrier family 5 member 6
decreases expression
EXP
Dieldrin results in decreased expression of SLC5A6 mRNA
CTD
PMID:23153324
NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:31,040,017...31,051,670
G
Slc6a12
solute carrier family 6 member 12
decreases expression
EXP
Dieldrin results in decreased expression of SLC6A12 mRNA
CTD
PMID:23153324
NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:156,254,208...156,275,879
G
Slc6a2
solute carrier family 6 member 2
affects expression
EXP
Dieldrin affects the expression of SLC6A2 mRNA
CTD
PMID:18812211
NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348
G
Slc6a3
solute carrier family 6 member 3
decreases expression increases expression multiple interactions
ISO EXP
Dieldrin results in decreased expression of SLC6A3 protein Dieldrin results in increased expression of SLC6A3 mRNA; Dieldrin results in increased expression of SLC6A3 protein Dieldrin inhibits the reaction [SLC6A3 protein affects the export of Dopamine]
CTD
PMID:11719704 PMID:16809432 PMID:17291500 PMID:18812211 PMID:19479021
NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962
G
Slc6a4
solute carrier family 6 member 4
decreases expression
EXP
Dieldrin results in decreased expression of SLC6A4 mRNA
CTD
PMID:18835401
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056
G
Slc6a8
solute carrier family 6 member 8
increases expression
EXP
Dieldrin results in increased expression of SLC6A8 mRNA
CTD
PMID:18812211
NCBI chr X:156,536,017...156,545,321
Ensembl chr X:156,536,017...156,545,321
G
Slc7a11
solute carrier family 7 member 11
multiple interactions
ISO
[Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA
CTD
PMID:20600679
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
G
Slc7a2
solute carrier family 7 member 2
decreases expression
EXP
Dieldrin results in decreased expression of SLC7A2 mRNA
CTD
PMID:23153324
NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256
G
Smap1
small ArfGAP 1
increases expression
ISO
Dieldrin results in increased expression of SMAP1 mRNA
CTD
PMID:31068361
NCBI chr 9:26,250,178...26,342,151
Ensembl chr 9:33,746,489...33,838,734
G
Smpd3
sphingomyelin phosphodiesterase 3
affects expression
EXP
Dieldrin affects the expression of SMPD3 mRNA
CTD
PMID:22546817
NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936
G
Smpd5
sphingomyelin phosphodiesterase 5
affects methylation
ISO
Dieldrin affects the methylation of SMPD5 gene
CTD
PMID:38995845
NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:109,889,875...109,893,384
G
Smyd3
SET and MYND domain containing 3
affects methylation
ISO
Dieldrin affects the methylation of SMYD3 gene
CTD
PMID:38995845
NCBI chr13:93,241,274...93,798,221
Ensembl chr13:93,241,279...93,798,237
G
Snca
synuclein alpha
multiple interactions increases expression
ISO EXP
Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein] Dieldrin results in increased expression of SNCA protein SNCA protein promotes the reaction [Dieldrin results in increased expression of CASP3 protein]
CTD
PMID:15987830 PMID:16809432 PMID:17291500
NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
G
Snora73b
small nucleolar RNA, H/ACA box 73b
increases expression
ISO
Dieldrin results in increased expression of SNORA73B mRNA
CTD
PMID:31068361
NCBI chr 5:144,545,179...144,545,382
Ensembl chr 5:149,829,190...149,829,393
G
Sod1
superoxide dismutase 1
decreases expression affects expression
EXP
Dieldrin results in decreased expression of SOD1 mRNA Dieldrin affects the expression of SOD1 mRNA
CTD
PMID:19440498 PMID:22546817
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
G
Sod2
superoxide dismutase 2
increases expression
EXP
Dieldrin results in increased expression of SOD2 mRNA
CTD
PMID:19440498
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
G
Son
SON DNA and RNA binding protein
affects expression
EXP
Dieldrin affects the expression of SON mRNA
CTD
PMID:22546817
NCBI chr11:44,336,818...44,409,127
Ensembl chr11:44,377,976...44,409,127
G
Sp1
Sp1 transcription factor
decreases response to substance
ISO
SP1 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
G
Spag5
sperm associated antigen 5
affects expression
EXP
Dieldrin affects the expression of SPAG5 mRNA
CTD
PMID:22546817
NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,696,466...63,714,811
G
Spata3
spermatogenesis associated 3
affects expression
EXP
Dieldrin affects the expression of SPATA3 mRNA
CTD
PMID:22546817
NCBI chr 9:86,660,352...86,672,272
Ensembl chr 9:94,107,807...94,119,172
G
Sqstm1
sequestosome 1
affects expression
EXP
Dieldrin affects the expression of SQSTM1 mRNA
CTD
PMID:22546817
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
G
Src
SRC proto-oncogene, non-receptor tyrosine kinase
affects expression
EXP
Dieldrin affects the expression of SRC mRNA
CTD
PMID:22546817
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
G
Srf
serum response factor
affects methylation
ISO
Dieldrin affects the methylation of SRF gene
CTD
PMID:38995845
NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:21,924,076...21,933,337
G
Srsf5
serine and arginine rich splicing factor 5
affects expression
EXP
Dieldrin affects the expression of SRSF5 mRNA
CTD
PMID:22546817
NCBI chr 6:106,333,998...106,341,467
Ensembl chr 6:106,336,756...106,341,931
G
Sstr3
somatostatin receptor 3
increases expression
EXP
Dieldrin results in increased expression of SSTR3 mRNA
CTD
PMID:20682304
NCBI chr 7:111,973,049...111,980,250
Ensembl chr 7:111,972,811...111,997,368
G
St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
affects methylation
ISO
Dieldrin affects the methylation of ST3GAL2 gene
CTD
PMID:38995845
NCBI chr19:55,798,112...55,849,226
Ensembl chr19:55,799,471...55,849,225
G
Stat1
signal transducer and activator of transcription 1
affects methylation
ISO
Dieldrin affects the methylation of STAT1 gene
CTD
PMID:38995845
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
G
Stat2
signal transducer and activator of transcription 2
decreases expression
EXP
Dieldrin results in decreased expression of STAT2 mRNA
CTD
PMID:34051100
NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459
G
Steap3
STEAP3 metalloreductase
affects expression
EXP
Dieldrin affects the expression of STEAP3 mRNA
CTD
PMID:22546817
NCBI chr13:33,904,710...33,950,100
Ensembl chr13:33,904,710...33,950,080
G
Stk11
serine/threonine kinase 11
decreases response to substance affects methylation
ISO
STK11 gene mutant form results in decreased susceptibility to Dieldrin Dieldrin affects the methylation of STK11 gene
CTD
PMID:32421776 PMID:38995845
NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965
G
Stk17b
serine/threonine kinase 17b
affects expression
EXP
Dieldrin affects the expression of STK17B mRNA
CTD
PMID:22546817
NCBI chr 9:55,307,485...55,338,085
Ensembl chr 9:62,803,005...62,832,511
G
Stk26
serine/threonine kinase 26
affects methylation
ISO
Dieldrin affects the methylation of STK26 gene
CTD
PMID:38995845
NCBI chr X:135,195,176...135,259,994
Ensembl chr X:135,195,204...135,259,993
G
Sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
affects expression
EXP
Dieldrin affects the expression of SUGT1 mRNA
CTD
PMID:22546817
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:61,400,004...61,468,852
G
Syk
spleen associated tyrosine kinase
affects methylation
ISO
Dieldrin affects the methylation of SYK gene
CTD
PMID:38995845
NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278
G
Syvn1
synoviolin 1
affects expression
EXP
Dieldrin affects the expression of SYVN1 mRNA
CTD
PMID:22546817
NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:212,768,907...212,776,457
G
Tac1
tachykinin, precursor 1
increases expression
EXP
Dieldrin results in increased expression of TAC1 mRNA
CTD
PMID:20682304
NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546
G
Tac4
tachykinin precursor 4
increases expression
EXP
Dieldrin results in increased expression of TAC4 mRNA
CTD
PMID:20682304
NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,701,987...80,712,972
G
Tagap
T-cell activation RhoGTPase activating protein
increases expression
ISO
Dieldrin results in increased expression of TAGAP mRNA
CTD
PMID:31068361
NCBI chr 1:49,575,750...49,584,747
Ensembl chr 1:49,575,750...49,583,838
G
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
affects methylation
ISO
Dieldrin affects the methylation of TANC1 gene
CTD
PMID:38995845
NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:64,508,085...64,741,825
G
Tap1
transporter 1, ATP binding cassette subfamily B member
decreases expression
ISO
Dieldrin results in decreased expression of TAP1 mRNA
CTD
PMID:31068361
NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810
G
Tbk1
TANK-binding kinase 1
affects methylation
ISO
Dieldrin affects the methylation of TBK1 gene
CTD
PMID:38995845
NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:58,963,325...58,996,357
G
Tbx2
T-box transcription factor 2
affects methylation
ISO
Dieldrin affects the methylation of TBX2 gene
CTD
PMID:38995845
NCBI chr10:71,177,082...71,186,275
Ensembl chr10:71,177,082...71,186,275
G
Tcf19
transcription factor 19
affects expression
EXP
Dieldrin affects the expression of TCF19 mRNA
CTD
PMID:22546817
NCBI chr20:3,223,464...3,227,569
Ensembl chr20:3,223,324...3,230,060
G
Tcf7
transcription factor 7
affects expression
EXP
Dieldrin affects the expression of TCF7 mRNA
CTD
PMID:22546817
NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,924,363...36,954,279
G
Tenm4
teneurin transmembrane protein 4
affects methylation
ISO
Dieldrin affects the methylation of TENM4 gene
CTD
PMID:38995845
NCBI chr 1:157,699,611...160,674,549
Ensembl chr 1:159,974,017...160,674,549
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Tfdp2
transcription factor Dp-2
affects expression
EXP
Dieldrin affects the expression of TFDP2 mRNA
CTD
PMID:22546817
NCBI chr 8:105,640,018...105,781,026
Ensembl chr 8:105,640,033...105,781,001
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Tgfb1
transforming growth factor, beta 1
multiple interactions decreases activity affects expression
EXP
Dieldrin inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein] Dieldrin results in decreased activity of TGFB1 protein Dieldrin affects the expression of TGFB1 mRNA
CTD
PMID:10200566 PMID:11238185 PMID:22546817
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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Tgfb3
transforming growth factor, beta 3
affects expression
EXP
Dieldrin affects the expression of TGFB3 mRNA
CTD
PMID:22546817
NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946
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Tgm2
transglutaminase 2
affects expression
EXP
Dieldrin affects the expression of TGM2 mRNA
CTD
PMID:22546817
NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
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Th
tyrosine hydroxylase
increases expression
EXP
Dieldrin results in increased expression of TH mRNA
CTD
PMID:18812211
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
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Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
affects expression
EXP
Dieldrin affects the expression of TIAL1 mRNA
CTD
PMID:22546817
NCBI chr 1:183,008,358...183,045,092
Ensembl chr 1:192,441,247...192,475,674
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Timp3
TIMP metallopeptidase inhibitor 3
affects expression
EXP
Dieldrin affects the expression of TIMP3 mRNA
CTD
PMID:22546817
NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547
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Tjp1
tight junction protein 1
decreases expression
EXP
Dieldrin results in decreased expression of TJP1 protein
CTD
PMID:15082077
NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
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Tjp3
tight junction protein 3
affects methylation
ISO
Dieldrin affects the methylation of TJP3 gene
CTD
PMID:38995845
NCBI chr 7:9,078,757...9,097,003
Ensembl chr 7:9,084,315...9,096,984
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Tle1
TLE family member 1, transcriptional corepressor
decreases expression
EXP
Dieldrin results in decreased expression of TLE1 mRNA
CTD
PMID:23153324
NCBI chr 5:90,898,182...90,982,118
Ensembl chr 5:90,898,182...90,980,928
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Tmbim6
transmembrane BAX inhibitor motif containing 6
affects expression
EXP
Dieldrin affects the expression of TMBIM6 mRNA
CTD
PMID:22546817
NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:132,386,134...132,422,492
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Tnf
tumor necrosis factor
increases expression multiple interactions
EXP ISO
Dieldrin results in increased expression of TNF mRNA; Dieldrin results in increased expression of TNF protein 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; Tacrolimus inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; Wortmannin inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]
CTD
PMID:13129777 PMID:15135310 PMID:31068361
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
Dieldrin results in increased expression of TNFAIP3 mRNA
CTD
PMID:31068361
NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979
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Tnfaip8
TNF alpha induced protein 8
affects expression
EXP
Dieldrin affects the expression of TNFAIP8 mRNA
CTD
PMID:22546817
NCBI chr18:43,183,854...43,299,512
Ensembl chr18:45,370,406...45,486,036
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Tnfrsf1a
TNF receptor superfamily member 1A
affects expression
EXP
Dieldrin affects the expression of TNFRSF1A mRNA
CTD
PMID:22546817
NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816
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Tnfsf9
TNF superfamily member 9
increases expression
ISO
Dieldrin results in increased expression of TNFSF9 mRNA
CTD
PMID:31068361
NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339
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Tp53
tumor protein p53
affects expression increases activity decreases response to substance
EXP ISO
Dieldrin affects the expression of TP53 mRNA Dieldrin results in increased activity of TRP53 protein TP53 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:22546817 PMID:22634143 PMID:32421776
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tph1
tryptophan hydroxylase 1
increases expression
EXP
Dieldrin results in increased expression of TPH1 mRNA
CTD
PMID:18835401
NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484
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Tradd
TNFRSF1A-associated via death domain
affects expression
EXP
Dieldrin affects the expression of TRADD mRNA
CTD
PMID:22546817
NCBI chr19:50,046,057...50,048,158
Ensembl chr19:50,046,061...50,052,550
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Trib3
tribbles pseudokinase 3
affects expression
EXP
Dieldrin affects the expression of TRIB3 mRNA
CTD
PMID:22546817
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802
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Trip13
thyroid hormone receptor interactor 13
increases expression
EXP
Dieldrin results in increased expression of TRIP13 mRNA
CTD
PMID:23153324
NCBI chr 1:31,185,700...31,230,638
Ensembl chr 1:31,185,594...31,230,634
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Tsc1
TSC complex subunit 1
affects expression increases response to substance
EXP ISO
Dieldrin affects the expression of TSC1 mRNA TSC1 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:22546817 PMID:32421776
NCBI chr 3:32,367,434...32,416,565
Ensembl chr 3:32,367,670...32,416,568
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Tsc2
TSC complex subunit 2
affects expression increases response to substance
EXP ISO
Dieldrin affects the expression of TSC2 mRNA TSC2 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:22546817 PMID:32421776
NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600
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Tsc22d3
TSC22 domain family, member 3
increases expression
ISO
Dieldrin results in increased expression of TSC22D3 mRNA
CTD
PMID:31068361
NCBI chr X:109,006,410...109,066,389
Ensembl chr X:109,006,420...109,015,519
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Tshz1
teashirt zinc finger homeobox 1
affects methylation
ISO
Dieldrin affects the methylation of TSHZ1 gene
CTD
PMID:38995845
NCBI chr18:79,651,256...79,727,662
Ensembl chr18:79,651,256...79,727,662
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Ttk
Ttk protein kinase
affects expression
EXP
Dieldrin affects the expression of TTK mRNA
CTD
PMID:22546817
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
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Ttpa
alpha tocopherol transfer protein
decreases expression
EXP
Dieldrin results in decreased expression of TTPA mRNA
CTD
PMID:23153324
NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:38,292,665...38,315,804
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Tube1
tubulin, epsilon 1
affects expression
EXP
Dieldrin affects the expression of TUBE1 mRNA
CTD
PMID:22546817
NCBI chr20:42,552,390...42,570,324
Ensembl chr20:44,107,022...44,125,271
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Txnip
thioredoxin interacting protein
decreases expression
ISO
Dieldrin results in decreased expression of TXNIP mRNA
CTD
PMID:31068361
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
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Uba6
ubiquitin-like modifier activating enzyme 6
increases response to substance
ISO
UBA6 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr14:22,238,832...22,302,650
Ensembl chr14:22,211,601...22,302,650
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Uba7
ubiquitin-like modifier activating enzyme 7
decreases expression
EXP
Dieldrin results in decreased expression of UBA7 mRNA
CTD
PMID:34051100
NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:117,543,957...117,556,142
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Ube2c
ubiquitin-conjugating enzyme E2C
affects expression
EXP
Dieldrin affects the expression of UBE2C mRNA
CTD
PMID:22546817
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:173,925,934...173,932,678
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Ube2k
ubiquitin-conjugating enzyme E2K
increases response to substance
ISO
UBE2K gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr14:42,658,016...42,718,899
Ensembl chr14:43,011,681...43,072,462
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Ube2l6
ubiquitin-conjugating enzyme E2L 6
decreases expression
EXP
Dieldrin results in decreased expression of UBE2L6 mRNA
CTD
PMID:34051100
NCBI chr 3:69,873,025...69,888,042
Ensembl chr 3:90,279,668...90,294,717
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Ube2n
ubiquitin-conjugating enzyme E2N
decreases response to substance decreases expression
ISO EXP
UBE2N gene mutant form results in decreased susceptibility to Dieldrin Dieldrin results in decreased expression of UBE2N mRNA
CTD
PMID:32421776 PMID:34051100
NCBI chr 7:30,154,330...30,184,373
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Ube2r2
ubiquitin-conjugating enzyme E2R 2
decreases response to substance
ISO
UBE2R2 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 5:61,082,552...61,141,099
Ensembl chr 5:61,082,552...61,141,452
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Unc5b
unc-5 netrin receptor B
affects expression
EXP
Dieldrin affects the expression of UNC5B mRNA
CTD
PMID:22546817
NCBI chr20:28,697,726...28,764,474
Ensembl chr20:29,240,650...29,307,270
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Uqcrh
ubiquinol-cytochrome c reductase hinge protein
decreases expression
EXP
Dieldrin results in decreased expression of UQCRH mRNA
CTD
PMID:23153324
NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:134,782,255...134,790,926
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Ush1g
USH1 protein network component sans
affects methylation
ISO
Dieldrin affects the methylation of USH1G gene
CTD
PMID:38995845
NCBI chr10:101,055,923...101,062,753
Ensembl chr10:101,057,208...101,062,564
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Usp18
ubiquitin specific peptidase 18
decreases expression
EXP
Dieldrin results in decreased expression of USP18 mRNA
CTD
PMID:34051100
NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:156,143,815...156,171,292
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Usp28
ubiquitin specific peptidase 28
decreases response to substance
ISO
USP28 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:58,222,220...58,282,750
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Vegfa
vascular endothelial growth factor A
increases secretion multiple interactions
ISO
Dieldrin results in increased secretion of VEGFA protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; fulvestrant inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; wortmannin inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]
CTD
PMID:18252963
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
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Vegfb
vascular endothelial growth factor B
affects expression
EXP
Dieldrin affects the expression of VEGFB mRNA
CTD
PMID:22546817
NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:213,600,966...213,607,152
G
Vegfc
vascular endothelial growth factor C
affects expression
EXP
Dieldrin affects the expression of VEGFC mRNA
CTD
PMID:22546817
NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887
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Vhl
von Hippel-Lindau tumor suppressor
affects expression
EXP
Dieldrin affects the expression of VHL mRNA
CTD
PMID:22546817
NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:148,328,079...148,334,991
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Vipr2
vasoactive intestinal peptide receptor 2
increases expression
EXP
Dieldrin results in increased expression of VIPR2 mRNA
CTD
PMID:20682304
NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:143,144,523...143,213,609
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Vmp1
vacuole membrane protein 1
increases expression
ISO
Dieldrin results in increased expression of VMP1 mRNA
CTD
PMID:31068361
NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,903,227...72,002,319
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Vwa5a
von Willebrand factor A domain containing 5A
affects expression
EXP
Dieldrin affects the expression of VWA5A mRNA
CTD
PMID:22546817
NCBI chr 8:38,815,176...38,848,674
Ensembl chr 8:47,712,369...47,736,307
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Wee1
WEE1 G2 checkpoint kinase
affects expression
EXP
Dieldrin affects the expression of WEE1 mRNA
CTD
PMID:22546817
NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449
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Wnt2
Wnt family member 2
decreases expression
EXP
Dieldrin results in decreased expression of WNT2 mRNA
CTD
PMID:19130878
NCBI chr 4:47,294,300...47,340,284
Ensembl chr 4:47,294,300...47,421,976
G
Wnt2b
Wnt family member 2B
decreases expression
EXP
Dieldrin results in decreased expression of WNT2B mRNA
CTD
PMID:19130878
NCBI chr 2:195,142,573...195,156,945
Ensembl chr 2:195,135,176...195,157,144
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Wnt3a
Wnt family member 3A
affects expression
EXP
Dieldrin affects the expression of WNT3A mRNA
CTD
PMID:19130878
NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919
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Wnt4
Wnt family member 4
affects expression
EXP
Dieldrin affects the expression of WNT4 mRNA
CTD
PMID:19130878
NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128
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Wnt5a
Wnt family member 5A
decreases expression
EXP
Dieldrin results in decreased expression of WNT5A mRNA
CTD
PMID:19130878
NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860
G
Wnt6
Wnt family member 6
increases expression
EXP
Dieldrin results in increased expression of WNT6 mRNA
CTD
PMID:19130878
NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:83,778,552...83,792,186
G
Wnt7a
Wnt family member 7A
decreases expression
EXP
Dieldrin results in decreased expression of WNT7A mRNA
CTD
PMID:19130878
NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149
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Wnt9a
Wnt family member 9A
affects expression
EXP
Dieldrin affects the expression of WNT9A mRNA
CTD
PMID:19130878
NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,593,691...44,620,682
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Wnt9b
Wnt family member 9B
affects expression
EXP
Dieldrin affects the expression of WNT9B mRNA
CTD
PMID:19130878
NCBI chr10:89,135,362...89,157,065
Ensembl chr10:89,135,363...89,157,065
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Wt1
WT1 transcription factor
affects expression
EXP
Dieldrin affects the expression of WT1 mRNA
CTD
PMID:22546817
NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:112,021,641...112,068,444
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Wwox
WW domain-containing oxidoreductase
affects expression
EXP
Dieldrin affects the expression of WWOX mRNA
CTD
PMID:22546817
NCBI chr19:59,338,402...60,269,323
Ensembl chr19:59,341,233...60,269,441
G
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
affects expression
EXP
Dieldrin affects the expression of WWP2 mRNA
CTD
PMID:22546817
NCBI chr19:52,256,563...52,380,967
Ensembl chr19:52,256,551...52,382,415
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Xylt1
xylosyltransferase 1
affects methylation
ISO
Dieldrin affects the methylation of XYLT1 gene
CTD
PMID:38995845
NCBI chr 1:181,078,222...181,361,047
Ensembl chr 1:181,078,222...181,361,047
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Zbtb16
zinc finger and BTB domain containing 16
affects expression
EXP
Dieldrin affects the expression of ZBTB16 mRNA
CTD
PMID:22546817
NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:57,891,081...58,073,507
G
Zbtb17
zinc finger and BTB domain containing 17
affects expression
EXP
Dieldrin affects the expression of ZBTB17 mRNA
CTD
PMID:22546817
NCBI chr 5:159,036,482...159,057,580
Ensembl chr 5:159,036,515...159,057,581
G
Zfp34
zinc finger protein 34
increases expression
ISO
Dieldrin results in increased expression of ZNF34 mRNA
CTD
PMID:31068361
NCBI chr 5:157,509,762...157,513,970
G
Zfp36
zinc finger protein 36
increases expression
ISO
Dieldrin results in increased expression of ZFP36 mRNA
CTD
PMID:31068361
NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:92,796,628...92,799,108
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Zfp36l1
zinc finger protein 36, C3H type-like 1
increases expression
ISO
Dieldrin results in increased expression of ZFP36L1 mRNA
CTD
PMID:31068361
NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979
G
Zmat3
zinc finger, matrin type 3
affects expression
EXP
Dieldrin affects the expression of ZMAT3 mRNA
CTD
PMID:22546817
NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:117,034,517...117,065,294
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