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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Fluorouracil]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine] |
CTD |
PMID:15897250 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Ano6 |
anoctamin 6 |
decreases activity |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of ANO6 protein |
CTD |
PMID:24478309 |
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NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid promotes the reaction [VIP protein results in increased expression of AQP3 mRNA] |
CTD |
PMID:12542607 |
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NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [TNF protein promotes the reaction [MAPK1 protein results in increased phosphorylation of ATF2 protein]] |
CTD |
PMID:9918806 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Best1 |
bestrophin 1 |
decreases activity |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of BEST1 protein |
CTD |
PMID:19828819 |
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NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063
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G |
Casp3 |
caspase 3 |
decreases expression |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased expression of CASP3 protein |
CTD |
PMID:21538933 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ccnd1 |
cyclin D1 |
increases expression |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in increased expression of CCND1 mRNA |
CTD |
PMID:21538933 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions decreases activity |
ISO EXP |
5-nitro-2-(3-phenylpropylamino)benzoic acid analog binds to and results in increased activity of CFTR protein; 5-nitro-2-(3-phenylpropylamino)benzoic acid analog binds to and results in increased activity of CFTR protein mutant form; 5-nitro-2-(3-phenylpropylamino)benzoic acid binds to and results in increased activity of CFTR protein; 5-nitro-2-(3-phenylpropylamino)benzoic acid binds to and results in increased activity of CFTR protein mutant form 5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein |
CTD |
PMID:15131065 PMID:15277574 PMID:15389550 PMID:15634668 PMID:15802612 PMID:15857825 More...
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NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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G |
Clcn3 |
chloride voltage-gated channel 3 |
decreases activity increases expression multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CLCN3 protein 5-nitro-2-(3-phenylpropylamino)benzoic acid results in increased expression of CLCN3 mRNA [5-nitro-2-(3-phenylpropylamino)benzoic acid results in increased expression of CLCN3 mRNA] which results in decreased susceptibility to Cisplatin |
CTD |
PMID:17699636 PMID:21538933 |
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NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
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G |
Gpr35 |
G protein-coupled receptor 35 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid binds to and results in increased activity of GPR35 protein |
CTD |
PMID:20826425 |
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NCBI chr 9:93,526,691...93,539,302
Ensembl chr 9:93,527,127...93,539,299
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [IFNG protein results in increased metabolism of Nitric Oxide] |
CTD |
PMID:9918806 PMID:19446535 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [TNF protein results in increased phosphorylation of JUN protein] |
CTD |
PMID:9918806 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [TNF protein promotes the reaction [MAPK1 protein results in increased phosphorylation of ATF2 protein]] |
CTD |
PMID:9918806 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA] |
CTD |
PMID:19446535 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Panx1 |
Pannexin 1 |
decreases activity |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of PANX1 protein |
CTD |
PMID:19023039 |
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NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774
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G |
Sct |
secretin |
decreases activity |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of SCT protein |
CTD |
PMID:10880878 |
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NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658
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G |
Slc16a1 |
solute carrier family 16 member 1 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates] |
CTD |
PMID:19023563 |
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NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
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G |
Slc5a5 |
solute carrier family 5 member 5 |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine] |
CTD |
PMID:27979590 |
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NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [TNF protein promotes the reaction [MAPK1 protein results in increased phosphorylation of ATF2 protein]]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [TNF protein results in increased phosphorylation of JUN protein]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [TNF protein results in increased transport of Chlorides] |
CTD |
PMID:9918806 PMID:10783394 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Vip |
vasoactive intestinal peptide |
multiple interactions |
ISO |
5-nitro-2-(3-phenylpropylamino)benzoic acid promotes the reaction [VIP protein results in increased expression of AQP3 mRNA] |
CTD |
PMID:12542607 |
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NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
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G |
Adora1 |
adenosine A1 receptor |
multiple interactions |
EXP |
[Dithiothreitol co-treated with Dithionitrobenzoic Acid] inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]; Cadmium Chloride promotes the reaction [Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]]; Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]; Dithionitrobenzoic Acid promotes the reaction [Cadmium Chloride inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]]; Dithiothreitol inhibits the reaction [Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]] |
CTD |
PMID:10413299 |
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NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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G |
Alb |
albumin |
multiple interactions increases reduction |
ISO |
[ALB protein binds to Docosahexaenoic Acids] inhibits the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Eicosapentaenoic Acid] inhibits the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Myristic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Oleic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Palmitic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to stearic acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein modified form binds to Myristic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [ALB protein modified form binds to Oleic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [ALB protein modified form binds to Palmitic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [ALB protein modified form binds to stearic acid] which results in decreased reduction of Dithionitrobenzoic Acid; [Pyruvaldehyde results in increased oxidation of ALB protein] which results in decreased reduction of Dithionitrobenzoic Acid |
CTD |
PMID:25451573 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Mt3 |
metallothionein 3 |
affects metabolic processing |
ISO |
MT3 protein polymorphism affects the metabolism of Dithionitrobenzoic Acid |
CTD |
PMID:14983064 |
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NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
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G |
Ptgr1 |
prostaglandin reductase 1 |
multiple interactions |
EXP |
Dithionitrobenzoic Acid inhibits the reaction [PTGR1 protein results in increased reduction of 10-nitro-oleic acid analog]; Dithionitrobenzoic Acid inhibits the reaction [PTGR1 protein results in increased reduction of 15-ketoprostaglandin E2] |
CTD |
PMID:23878198 |
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NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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G |
Txnrd1 |
thioredoxin reductase 1 |
multiple interactions increases reduction affects metabolic processing |
ISO EXP |
Dinitrochlorobenzene inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid]; diphenyleneiodonium inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid]; Gold Sodium Thiomalate inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid] TXNRD1 protein results in increased reduction of Dithionitrobenzoic Acid [Dinitrochlorobenzene binds to TXNRD1 protein] inhibits the reaction [TXNRD1 protein results in increased reduction of Dithionitrobenzoic Acid]; Dithionitrobenzoic Acid inhibits the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides]; Ferrous Compounds inhibits the reaction [TXNRD1 protein results in increased reduction of Dithionitrobenzoic Acid] |
CTD |
PMID:17229725 PMID:20457604 PMID:21172426 |
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NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Txnrd2 |
thioredoxin reductase 2 |
increases reduction |
ISO |
TXNRD2 protein results in increased reduction of Dithionitrobenzoic Acid |
CTD |
PMID:21172426 |
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NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
bifenox binds to and results in increased activity of AHR protein |
CTD |
PMID:18835618 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
bifenox inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [bifenox results in increased activity of AR protein] |
CTD |
PMID:15064155 PMID:18324785 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
bifenox binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:21115097 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
bifenox results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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