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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:7,12-dimethyltetraphene
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Accession:CHEBI:254496 term browser browse the term
Definition:A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke.
Synonyms:related_synonym: 1,4-Dimethyl-2,3-benzphenanthrene;   6,7-Dimethyl-1,2-benzanthracene;   7,12-DMBA;   7,12-Dimethyl-1,2-benzanthracene;   7,12-Dimethyl-1:2-benz(a)anthracene;   7,12-Dimethylbenz(a)anthracene;   7,12-Dimethylbenzanthracene;   7,12-Dimethylbenzanthrancene;   7,12-dimethylbenzo[a]anthracene;   9,10-Dimethyl-1,2-benzanthracene;   9,10-Dimethyl-1,2-benzanthrazen;   9,10-Dimethylbenz(a)anthracene;   DMBA;   Formula=C20H16;   InChI=1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3;   InChIKey=ARSRBNBHOADGJU-UHFFFAOYSA-N;   SMILES=Cc1c2ccccc2c(C)c2c1ccc1ccccc21
 alt_id: CHEBI:59032
 xref: Beilstein:1912135;   CAS:57-97-6;   Gmelin:263937;   KEGG:C19488;   LINCS:LSM-37159
 xref_mesh: MESH:D015127
 xref: PMID:11488430;   PMID:12839762;   PMID:16020197;   PMID:18992763;   PMID:7561049


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7,12-dimethyltetraphene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP binding cassette subfamily C member 6 affects response to substance ISO ABCC6 gene SNP affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene CTD PMID:25622337 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ABHD3 mRNA CTD PMID:21527772 NCBI chr18:1,892,413...1,946,840
Ensembl chr18:1,892,413...1,946,840
JBrowse link
G Actb actin, beta affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of ACTB mRNA CTD PMID:21785161 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ACTG2 mRNA CTD PMID:19480007 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Actn1 actinin, alpha 1 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ACTN1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of ACTN1 protein
CTD PMID:22248470 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn3 actinin alpha 3 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ACTN3 mRNA CTD PMID:19480007 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Actn4 actinin alpha 4 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ACTN4 mRNA CTD PMID:12376462 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Actr3b actin related protein 3B increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ACTR3B mRNA CTD PMID:19480007 NCBI chr 4:5,644,287...5,672,708
Ensembl chr 4:5,644,260...5,672,708
JBrowse link
G Adcy5 adenylate cyclase 5 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ADCY5 mRNA CTD PMID:12376462 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adgrl4 adhesion G protein-coupled receptor L4 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ADGRL4 mRNA CTD PMID:19480007 NCBI chr 2:256,609,787...256,724,642
Ensembl chr 2:256,609,787...256,724,641
JBrowse link
G Adm adrenomedullin increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ADM mRNA CTD PMID:19480007 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adss adenylosuccinate synthase affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of ADSS mRNA CTD PMID:21785161 NCBI chr13:95,913,426...95,943,761
Ensembl chr13:95,913,426...95,943,761
JBrowse link
G Ago2 argonaute RISC catalytic component 2 increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 protein
Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 mRNA]; Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 protein]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 protein]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 mRNA]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 protein]
CTD PMID:24792773 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of AHCYL1 mRNA CTD PMID:21785161 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
affects localization
affects binding
increases expression
affects response to substance
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein
9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein results in increased expression of CCL5 mRNA]; AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA]; AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA]; AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the localization of AHR protein]
9,10-Dimethyl-1,2-benzanthracene binds to and results in increased activity of AHR protein; [AHR mRNA affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which results in decreased expression of CYP1A1; AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of ARTN protein]; AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL4RA]; AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TSLP]; galangin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the localization of AHR protein]
9,10-Dimethyl-1,2-benzanthracene binds to AHR protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of AHR mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AHR protein
AHR affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene; AHR mRNA affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene binds to and results in increased activity of AHR protein; AHR protein promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA]
CTD PMID:3024361, PMID:9855628, PMID:10953044, PMID:12117779, PMID:12200463, PMID:12559965, PMID:14678569, PMID:15667830, PMID:16903077, PMID:17275817, PMID:18205319, PMID:20562217, PMID:22406437, PMID:25110319, PMID:27869817 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of AHRR mRNA CTD PMID:27891153 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 multiple interactions ISO AKR7A2 protein results in increased reduction of and affects the activity of 9,10-Dimethyl-1,2-benzanthracene CTD PMID:21910479 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
increases phosphorylation
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased expression of AKT1 protein modified form
9,10-Dimethyl-1,2-benzanthracene results in increased expression of AKT1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of AKT1 protein
CTD PMID:21785161, PMID:24576726 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ALAS2 mRNA CTD PMID:19480007 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ALDOA protein CTD PMID:22248470 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ANAPC5 mRNA CTD PMID:21785161 NCBI chr12:39,209,134...39,242,696
Ensembl chr12:39,209,129...39,242,690
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions
increases methylation
EXP [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of ANGPTL4 promoter] which results in decreased expression of ANGPTL4 mRNA CTD PMID:21489049 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ANK mRNA CTD PMID:19480007 NCBI chr 2:80,131,563...80,256,948
Ensembl chr 2:80,131,563...80,256,954
JBrowse link
G Anxa1 annexin A1 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ANXA1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of ANXA1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ANXA1 protein
CTD PMID:12376462, PMID:22248470 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa2 annexin A2 multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ANXA2 protein CTD PMID:22248470 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions
decreases expression
ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]; resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein
CTD PMID:18791811, PMID:25478867 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression
ISO Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of APEX1 mRNA] CTD PMID:25697376 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoc1 apolipoprotein C1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of APOC1 mRNA CTD PMID:21785161 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoe apolipoprotein E affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of APOE mRNA CTD PMID:21785161 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of AQP1 mRNA CTD PMID:12376462 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AQP3 mRNA CTD PMID:19480007 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp5 aquaporin 5 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of AQP5 mRNA CTD PMID:19480007 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Ar androgen receptor multiple interactions
increases activity
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene binds to and results in decreased activity of AR protein; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Metribolone results in increased activity of AR protein]
9,10-Dimethyl-1,2-benzanthracene results in increased activity of AR protein
CTD PMID:10771140, PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arl16 ADP-ribosylation factor like GTPase 16 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of ARL16 mRNA CTD PMID:21785161 NCBI chr10:109,636,770...109,639,018
Ensembl chr10:109,636,896...109,639,054
JBrowse link
G Artn artemin multiple interactions
increases expression
ISO AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of ARTN protein] CTD PMID:27869817 NCBI chr 5:136,759,717...136,765,036
Ensembl chr 5:136,759,717...136,762,986
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of ASAH1 mRNA CTD PMID:21785161 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asip agouti signaling protein multiple interactions ISO 9,10-Dimethyl-1,2-benzanthracene affects the reaction [A gene mutant form results in decreased expression of GJA4 protein]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [A gene mutant form results in decreased expression of ATM mRNA]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [A gene mutant form results in decreased expression of BRCA1 protein]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [A gene mutant form results in decreased expression of PRKDC mRNA]; 9,10-Dimethyl-1,2-benzanthracene promotes the reaction [A gene mutant form results in increased expression of PARP1 mRNA]; 9,10-Dimethyl-1,2-benzanthracene promotes the reaction [A gene mutant form results in increased expression of PARP1 protein]; [A gene mutant form co-treated with 9,10-Dimethyl-1,2-benzanthracene] affects the expression of GJA4 protein; A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GJA1 mRNA]; A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of H2AX protein]; A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 protein]; A gene mutant form inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BRCA1 protein]; A gene mutant form inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 mRNA]; A gene mutant form inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of XRCC6 protein] CTD PMID:25447408, PMID:25448685 NCBI chr 3:150,492,010...150,579,870
Ensembl chr 3:150,574,473...150,579,870
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
decreases expression
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased phosphorylation of ATM protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of ATM protein
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ATM mRNA
9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [A gene mutant form results in decreased expression of ATM mRNA]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of ATM mRNA
CTD PMID:23969067, PMID:25448685 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ATP5F1A protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ATP5F1A protein
CTD PMID:22248470 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ATP5F1B protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of ATP5F1B protein
CTD PMID:22248470 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ATPIF1 mRNA CTD PMID:12376462 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of ATP6AP2 mRNA CTD PMID:21785161 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BASP1 mRNA CTD PMID:12376462 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of BAX mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BAX mRNA
Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of BAX mRNA]
CTD PMID:18791811, PMID:20562217, PMID:22760862, PMID:24269759, PMID:25478867, PMID:30101532 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 protein; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; [Plant Extracts co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; Resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]
Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein
CTD PMID:18791811, PMID:20103723, PMID:20537511, PMID:22760862, PMID:25478867, PMID:30101532 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BECN1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BECN1 protein CTD PMID:24576726 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 protein
resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 protein]
CTD PMID:18791811 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 protein
Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 protein]
CTD PMID:24792773 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Brat1 BRCA1-associated ATM activator 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of BRAT1 mRNA CTD PMID:21785161 NCBI chr12:16,016,062...16,028,534
Ensembl chr12:16,015,771...16,027,881
JBrowse link
G Brca1 BRCA1, DNA repair associated affects response to substance
increases expression
multiple interactions
ISO
EXP
BRCA1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene results in increased expression of BRCA1 protein
9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [A gene mutant form results in decreased expression of BRCA1 protein]; A gene mutant form inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BRCA1 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of BRCA1 mRNA
CTD PMID:21507987, PMID:23969067, PMID:25448685 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G C1qb complement C1q B chain affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of C1QB mRNA CTD PMID:21785161 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C1qc complement C1q C chain affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of C1QC mRNA CTD PMID:21785161 NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
JBrowse link
G C1s complement C1s affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of C1S mRNA CTD PMID:21785161 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C3 complement C3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of C3 mRNA CTD PMID:19480007 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CAR3 protein CTD PMID:20045496 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Calr calreticulin increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CALR mRNA CTD PMID:21785161 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of CAPZA2 protein CTD PMID:22248470 NCBI chr 4:44,936,290...44,972,270
Ensembl chr 4:44,936,290...44,972,267
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CAR2 mRNA CTD PMID:19480007 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CASK mRNA CTD PMID:12376462 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Casp2 caspase 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CASP2 protein CTD PMID:21785161 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
decreases activity
increases expression
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased cleavage of and results in increased activity of CASP3 protein; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]; amarogentin inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased cleavage of and results in increased activity of CASP3 protein]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]; Plant Extracts inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased cleavage of and results in increased activity of CASP3 protein]
Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CASP3 protein
CTD PMID:16517061, PMID:21785161, PMID:23969067, PMID:25478867, PMID:30101532 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 decreases activity
decreases expression
multiple interactions
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein
Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]
CTD PMID:25478867, PMID:30101532 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of CAT protein; geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein
allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]; zingerone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]
CTD PMID:20691676, PMID:23033690, PMID:24995432, PMID:25744308, PMID:31476248 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbln2 cerebellin 2 precursor decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CBLN2 mRNA CTD PMID:19480007 NCBI chr18:83,775,568...83,783,841
Ensembl chr18:83,777,665...83,782,930
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
EXP citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCL3 mRNA] CTD PMID:31926054 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
increases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein results in increased expression of CCL5 mRNA]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCL5 mRNA
CTD PMID:12200463, PMID:19480007 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CCL6 mRNA CTD PMID:19480007 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCN2 mRNA CTD PMID:19480007 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCN3 mRNA CTD PMID:19480007 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCNB1 protein CTD PMID:20025956 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCND1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCND1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCND1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCND1 protein
CTD PMID:12097258, PMID:12376462, PMID:21785161, PMID:29663660 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd3d CD3d molecule increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CD3D mRNA CTD PMID:19480007 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd3g CD3g molecule increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CD3G mRNA CTD PMID:19480007 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cd5 Cd5 molecule increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CD5 mRNA CTD PMID:19480007 NCBI chr 1:226,770,912...226,791,861
Ensembl chr 1:226,770,744...226,791,879
JBrowse link
G Cd52 CD52 molecule decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CD52 mRNA CTD PMID:19480007 NCBI chr 5:152,322,910...152,324,469
Ensembl chr 5:152,322,916...152,324,469
JBrowse link
G Cd59 CD59 molecule multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein CTD PMID:19965957, PMID:20202993 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cd6 Cd6 molecule increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CD6 mRNA CTD PMID:19480007 NCBI chr 1:226,848,399...226,887,259
Ensembl chr 1:226,848,403...226,887,156
JBrowse link
G Cd74 CD74 molecule affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of CD74 mRNA CTD PMID:21785161 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd93 CD93 molecule increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CD93 mRNA CTD PMID:19480007 NCBI chr 3:142,778,798...142,783,774
Ensembl chr 3:142,778,770...142,783,774
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH1 protein CTD PMID:29663660 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh13 cadherin 13 multiple interactions
decreases expression
EXP AHR protein promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA] CTD PMID:12559965, PMID:19480007 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDK4 mRNA CTD PMID:12376462 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein]; [epigallocatechin gallate co-treated with Polylactic Acid-Polyglycolic Acid Copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]; [Plant Extracts co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]; [Resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]; [theaflavin co-treated with Polylactic Acid-Polyglycolic Acid Copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein]; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein]; theaflavin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A protein
CTD PMID:20043298, PMID:20103723, PMID:21527772, PMID:21785161, PMID:23717041, PMID:25478867 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases response to substance
multiple interactions
increases methylation
decreases expression
ISO CDKN2A gene polymorphism results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene
Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A protein]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CDKN2A promoter]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CDKN2A promoter]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CDKN2A promoter]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A protein
CTD PMID:11544531, PMID:24792773 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN2B mRNA CTD PMID:19480007 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cercam cerebral endothelial cell adhesion molecule decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CERCAM mRNA CTD PMID:19480007 NCBI chr 3:8,421,116...8,444,743
Ensembl chr 3:8,430,829...8,444,851
JBrowse link
G Cfd complement factor D decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CFD mRNA CTD PMID:19480007 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CHEK1 protein CTD PMID:20025956 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chi3l1 chitinase 3 like 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of CHI3L1 mRNA CTD PMID:21785161 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Cidec cell death-inducing DFFA-like effector c decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CIDEC mRNA CTD PMID:19480007 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Clca1 chloride channel accessory 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CLCA1 mRNA CTD PMID:19480007 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
JBrowse link
G Cldn3 claudin 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CLDN3 mRNA CTD PMID:12097258 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cnn3 calponin 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CNN3 mRNA CTD PMID:12376462 NCBI chr 2:225,005,069...225,036,179
Ensembl chr 2:225,005,019...225,036,188
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of COL1A2 mRNA CTD PMID:19480007 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of COL5A1 mRNA CTD PMID:12376462 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a3 collagen type V alpha 3 chain decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of COL5A3 mRNA CTD PMID:19480007 NCBI chr 8:21,786,324...21,831,751
Ensembl chr 8:21,786,324...21,831,668
JBrowse link
G Coro1a coronin 1A increases methylation
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CORO1A promoter
[9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CORO1A promoter] which results in decreased expression of CORO1A mRNA
CTD PMID:21489049 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CREB3L3 mRNA CTD PMID:27891153 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Csde1 cold shock domain containing E1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of CSDE1 mRNA CTD PMID:21785161 NCBI chr 2:205,525,194...205,552,987
Ensembl chr 2:205,525,204...205,552,991
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Fluoxetine] affects the expression of CSF1R protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of CSF1R protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of CSF1R protein CTD PMID:31332895 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CSF2 mRNA CTD PMID:14678569 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CSF3 mRNA CTD PMID:14678569 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csn1s1 casein alpha s1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CSN1S1 mRNA CTD PMID:19480007 NCBI chr14:21,993,450...22,009,308
Ensembl chr14:21,993,427...22,009,308
JBrowse link
G Csn2 casein beta decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CSN2 protein CTD PMID:22248470 NCBI chr14:21,972,274...21,979,511
Ensembl chr14:21,972,274...21,979,510
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTNNB1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of and affects the localization of CTNNB1 protein; mithramycin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of and affects the localization of CTNNB1 protein]; SP1 protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTNNB1 protein]
CTD PMID:29663660 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsd cathepsin D increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTSD mRNA CTD PMID:12097258 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsw cathepsin W increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTSW mRNA CTD PMID:19480007 NCBI chr 1:220,844,579...220,847,967
Ensembl chr 1:220,844,558...220,848,153
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CXCL10 mRNA CTD PMID:27891153 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of CXCL13 mRNA CTD PMID:21785161 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions
increases expression
EXP tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYB5A protein]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYB5A protein] CTD PMID:24995432, PMID:27091720 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of CYB5R3 mRNA CTD PMID:21785161 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases response to substance
increases expression
increases metabolic processing
multiple interactions
affects response to substance
increases activity
ISO
EXP
CYP1A1 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 protein
CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene
7-ketocholesterol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 mRNA]; 7-ketocholesterol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein]; [Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 mRNA; [Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein; Estradiol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein]
CYP1A1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene
2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; 5-androstene-16-fluoro-17-one inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; 7-ketocholesterol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 protein]; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1A1 protein; [CYP1A1 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene; [Tetrachlorodibenzodioxin promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; CYP1A1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene; Dehydroepiandrosterone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; Dehydroepiandrosterone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; Eugenol inhibits the reaction [CYP1A1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 protein]; Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1A1 protein]; Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]
1-(1-propynyl)pyrene inhibits the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1A1 protein; [[benzo(c)phenanthrene results in increased expression of CYP1A1 protein] promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog; [AHR mRNA affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which results in decreased expression of CYP1A1; [benzo(c)phenanthrene promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog; [CYP1A1 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog; EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]
CTD PMID:7756127, PMID:8674863, PMID:8961944, PMID:9168260, PMID:10051580, PMID:10496959, PMID:10496962, PMID:10575002, PMID:10581206, PMID:11042205, PMID:11559018, PMID:12097275, PMID:12117779, PMID:15331171, PMID:15596260, PMID:15667830, PMID:16054776, PMID:16903077, PMID:17183067, PMID:17275817, PMID:18205319, PMID:19276279, PMID:20507880, PMID:22595614, PMID:25110319, PMID:25697376, PMID:26945725, PMID:27869817, PMID:27891153, PMID:32159784 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
multiple interactions
increases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein
2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]; [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]; S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]
CYP1A2 protein results in increased activity of 9,10-Dimethyl-1,2-benzanthracene
CTD PMID:8961944, PMID:15606143, PMID:16054776, PMID:17183067, PMID:19276279, PMID:25110319 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases activity
increases expression
multiple interactions
increases metabolic processing
affects response to substance
increases response to substance
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA
2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; 5-androstene-16-fluoro-17-one inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [[benzo(c)phenanthrene results in increased expression of CYP1B1 protein] promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog; CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; Eugenol inhibits the reaction [CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]; S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein
Estradiol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; POMC protein promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]
1-ethynylpyrene inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1B1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Dietary Fats] results in decreased expression of CYP1B1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of AHRR mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CREB3L3 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CXCL10 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CYP1A1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of EGR2 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of ERDR1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HBB-B1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HOXB6 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HSPA1A mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of IL6 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of NR4A1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of POLR2A mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of RAG1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of SOX19 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of SPP1 mRNA; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of TNF mRNA; [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; chelerythrine inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Dehydroepiandrosterone inhibits the reaction [benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; Dehydroepiandrosterone inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Dehydroepiandrosterone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; POR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]; PRKCB protein inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; PRKCB protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]
CYP1B1 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene; CYP1B1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene
CYP1B1 protein results in increased activity of 9,10-Dimethyl-1,2-benzanthracene
CTD PMID:7505439, PMID:7588239, PMID:8033136, PMID:8674863, PMID:9168260, PMID:10037446, PMID:10497882, PMID:10581206, PMID:11323178, PMID:11376689, PMID:11559018, PMID:12097275, PMID:12117779, PMID:15331171, PMID:15580705, PMID:15596260, PMID:15606143, PMID:15667830, PMID:15843505, PMID:17183067, PMID:17275817, PMID:17442664, PMID:18205319, PMID:19276279, PMID:19750107, PMID:20103723, PMID:20171256, PMID:21252291, PMID:22595614, PMID:25110319, PMID:26945725, PMID:27891153, PMID:32159784 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B1 protein
beta-Naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B1 protein]
CTD PMID:16054776 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases activity
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B2 protein
beta-Naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B2 protein]
CTD PMID:16054776 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO CYP2B6 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene CTD PMID:32159784 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO CYP2C19 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene CTD PMID:32159784 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases response to substance ISO CYP2D6 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene CTD PMID:20507880 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects response to substance
increases expression
ISO
EXP
CYP2E1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP2E1 mRNA
CTD PMID:18622027, PMID:24576726 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of 9,10-Dimethyl-1,2-benzanthracene CTD PMID:19713358 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Dars1 aspartyl-tRNA synthetase 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of DARS mRNA CTD PMID:21785161 NCBI chr13:45,074,067...45,127,815
Ensembl chr13:45,074,072...45,127,815
JBrowse link
G Dazl deleted in azoospermia-like decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DAZL mRNA
AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA]
CTD PMID:20562217 NCBI chr 9:12,633,983...12,651,017
Ensembl chr 9:12,633,990...12,650,938
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DBI mRNA CTD PMID:12376462 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dchs1 dachsous cadherin-related 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DCHS1 mRNA CTD PMID:19480007 NCBI chr 1:170,594,981...170,629,062
Ensembl chr 1:170,594,822...170,628,915
JBrowse link
G Dcn decorin multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of DCN protein CTD PMID:22248470 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddx39b DExD-box helicase 39B multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of DDX39B protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of DDX39B protein
CTD PMID:22248470 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568
JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DDX4 mRNA
AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA]
CTD PMID:20562217 NCBI chr 2:44,447,610...44,504,263
Ensembl chr 2:44,447,573...44,504,354
JBrowse link
G Ddx5 DEAD-box helicase 5 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DDX5 mRNA CTD PMID:21785161 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Des desmin decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DES mRNA CTD PMID:12376462 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dicer1 dicer 1 ribonuclease III increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 protein
Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 mRNA]; Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 protein]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 protein]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 mRNA]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 protein]
CTD PMID:24792773 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNAJB6 mRNA CTD PMID:21785161 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression
multiple interactions
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA
Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA]; Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 protein]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 protein]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 protein
CTD PMID:12097258, PMID:24792773 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dpt dermatopontin decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DPT mRNA CTD PMID:19480007 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 1:211,423,022...211,438,533
Ensembl chr 1:211,423,022...211,438,531
JBrowse link
G Dynll2 dynein light chain LC8-type 2 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of DYNLL2 mRNA CTD PMID:21785161 NCBI chr10:75,262,536...75,281,302
Ensembl chr10:75,262,537...75,270,561
JBrowse link
G Ecrg4 ECRG4 augurin precursor increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ECRG4 mRNA CTD PMID:19480007 NCBI chr 9:50,526,811...50,548,056
Ensembl chr 9:50,526,811...50,548,046
JBrowse link
G Ednrb endothelin receptor type B decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of EDNRB mRNA CTD PMID:19480007 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of EEF1A1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of EEF1A1 protein
CTD PMID:12376462, PMID:20045496 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of EEF2 mRNA CTD PMID:21785161 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of EFEMP1 mRNA CTD PMID:12376462 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egr1 early growth response 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of EGR1 mRNA CTD PMID:19480007 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of EGR2 mRNA CTD PMID:27891153 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of EIF4B mRNA CTD PMID:21785161 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of EIF4G2 mRNA CTD PMID:21785161 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G Eno1 enolase 1 multiple interactions
increases expression
decreases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ENO1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of ENO1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ENO1 protein
CTD PMID:12376462, PMID:22248470 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions
increases expression
decreases expression
affects response to substance
increases response to substance
ISO
EXP
EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of EPHX1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of EPHX1 protein
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of EPHX1 mRNA
EPHX1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene
EPHX1 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene; EPHX1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene
[cyclohexene oxide results in decreased activity of EPHX1 protein] which results in decreased susceptibility to 9,10-Dimethyl-1,2-benzanthracene; EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; EPHX1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene
CTD PMID:8961944, PMID:11323178, PMID:12376462, PMID:15331171, PMID:17204581, PMID:17442664, PMID:19027032, PMID:24576726 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Epo erythropoietin decreases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of EPO mRNA CTD PMID:19502547 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA
[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]; epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]
CTD PMID:23717041 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Erp29 endoplasmic reticulum protein 29 multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ERP29 protein CTD PMID:22248470 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ESR1 protein
[Estradiol co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of ESR1 protein; [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of ESR1 protein
CTD PMID:16891317 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Exoc3l4 exocyst complex component 3-like 4 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of EXOC3L4 mRNA CTD PMID:19480007 NCBI chr 6:135,866,132...135,880,724
Ensembl chr 6:135,866,739...135,880,721
JBrowse link
G Ezr ezrin multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of EZR protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of EZR mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of EZR protein
CTD PMID:12376462, PMID:22248470 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of FASN protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of FASN protein
CTD PMID:22248470 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbn2 fibrillin 2 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FBN2 mRNA CTD PMID:19480007 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression
increases methylation
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FHIT mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FHIT protein
9,10-Dimethyl-1,2-benzanthracene results in increased methylation of FHIT intron; 9,10-Dimethyl-1,2-benzanthracene results in increased methylation of FHIT promoter
CTD PMID:15937960 NCBI chr15:15,697,292...16,862,873 JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of FHL2 mRNA CTD PMID:19480007 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Flnc filamin C increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fn1 fibronectin 1 multiple interactions
decreases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of FN1 protein
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FN1 mRNA
CTD PMID:12376462, PMID:22248470 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]
CTD PMID:20103723 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxn3 forkhead box N3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOXN3 mRNA CTD PMID:21785161 NCBI chr 6:123,183,720...123,577,719
Ensembl chr 6:123,187,726...123,577,695
JBrowse link
G Foxo3 forkhead box O3 decreases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FOXO3 protein CTD PMID:21785161 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of FURIN mRNA CTD PMID:12376462 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Fus FUS RNA binding protein affects expression
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of FUS mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FUS mRNA
CTD PMID:19480007, PMID:21785161 NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression
ISO [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of GADD45A mRNA]; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of GADD45A mRNA]; epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of GADD45A mRNA] CTD PMID:23717041 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression
increases expression
multiple interactions
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GAPDH mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of GAPDH protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of GAPDH protein
CTD PMID:19502547, PMID:22248470 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gas5 growth arrest specific 5 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GAS5 mRNA CTD PMID:19480007 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gbp5 guanylate binding protein 5 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GBP5 mRNA CTD PMID:19480007 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Gda guanine deaminase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GDA mRNA CTD PMID:12376462 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GGT1 mRNA CTD PMID:12376462 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 decreases response to substance EXP GH1 gene mutant form results in decreased susceptibility to 9,10-Dimethyl-1,2-benzanthracene CTD PMID:12082019 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gimap5 GTPase, IMAP family member 5 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GIMAP5 mRNA CTD PMID:19480007 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
decreases expression
increases expression
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased expression of GJA1 mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJA1 mRNA; A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GJA1 mRNA]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GJA1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GJA1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of GJA1 protein
CTD PMID:7586191, PMID:24269759, PMID:25447408 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja4 gap junction protein, alpha 4 decreases expression
multiple interactions
increases expression
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GJA4 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GJA4 protein
9,10-Dimethyl-1,2-benzanthracene affects the reaction [A gene mutant form results in decreased expression of GJA4 protein]; [A gene mutant form co-treated with 9,10-Dimethyl-1,2-benzanthracene] affects the expression of GJA4 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of GJA4 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GJA4 protein
CTD PMID:24269759, PMID:25447408 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221
JBrowse link
G Gjb2 gap junction protein, beta 2 multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] affects the expression of GJB2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJB2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJB2 mRNA CTD PMID:7586191 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Gjb5 gap junction protein, beta 5 multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJB5 mRNA CTD PMID:7586191 NCBI chr 5:145,422,034...145,440,558
Ensembl chr 5:145,422,357...145,423,172
JBrowse link
G Gls glutaminase increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GLS mRNA CTD PMID:21527772 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gng12 G protein subunit gamma 12 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GNG12 mRNA CTD PMID:19480007 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Gp2 glycoprotein 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GP2 mRNA CTD PMID:19480007 NCBI chr 1:189,166,735...189,182,306
Ensembl chr 1:189,166,399...189,182,306
JBrowse link
G Gpr68 G protein-coupled receptor 68 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GPR68 mRNA CTD PMID:19480007 NCBI chr 6:124,874,151...124,903,949
Ensembl chr 6:124,874,151...124,876,710
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GPX2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GPX2 protein CTD PMID:18056462 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
decreases activity
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of GSR protein; geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein
allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]; zingerone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]
CTD PMID:20691676, PMID:23033690, PMID:24995432, PMID:25744308, PMID:31476248 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of GSS mRNA CTD PMID:12376462 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance
increases expression
decreases expression
multiple interactions
EXP GSTP1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene results in increased expression of GSTP1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSTP1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of GSTP1 protein
CTD PMID:12097258, PMID:22406437, PMID:24576726 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G H1f4 H1.4 linker histone, cluster member multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of H1F4 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of H1F4 protein
CTD PMID:22248470 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of H2AX protein
A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of H2AX protein]
CTD PMID:23969067, PMID:25448685 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hal histidine ammonia lyase multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of HAL protein CTD PMID:20691676 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HBA1 mRNA CTD PMID:12376462 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HBB-B1 mRNA CTD PMID:27891153 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hdac1 histone deacetylase 1 increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 protein
Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 mRNA]; Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 protein]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 protein]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 mRNA]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 protein]
CTD PMID:24792773 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of HELLS protein CTD PMID:20025956 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases activity
affects expression
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased activity of HIF1A protein
9,10-Dimethyl-1,2-benzanthracene affects the expression of HIF1A mRNA
CTD PMID:19502547, PMID:21785161 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HIST1H2BQ protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of HIST1H2BQ protein
CTD PMID:22248470 NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of H2AC18 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of H2AC18 protein
CTD PMID:22248470 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HMOX1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HMOX1 protein
tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HMOX1 mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HMOX1 protein]
CTD PMID:12097258, PMID:24995432 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of HNRNPA2B1 mRNA CTD PMID:21785161 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of HNRNPK mRNA CTD PMID:21785161 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HNRNPM protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of HNRNPM protein
CTD PMID:22248470 NCBI chr 7:18,516,253...18,554,536
Ensembl chr 7:18,516,512...18,554,227
JBrowse link
G Hoxb6 homeo box B6 multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HOXB6 mRNA CTD PMID:27891153 NCBI chr10:84,147,331...84,150,238
Ensembl chr10:84,147,836...84,149,600
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases mutagenesis
increases response to substance
ISO 4-octylphenol affects the reaction [HRAS protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene]; Estradiol affects the reaction [HRAS protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene]
9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene
[9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased mutagenesis of HRAS gene; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate co-treated with mezerein] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of HRAS protein
CTD PMID:1375869, PMID:3115617, PMID:11241758, PMID:11376698, PMID:12117780, PMID:20103723, PMID:22760862 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HSP90AB1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of HSP90AB1 protein
CTD PMID:22248470 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HSPA1A mRNA CTD PMID:27891153 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HSPA5 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of HSPA5 protein
CTD PMID:22248470 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of HSPA8 mRNA CTD PMID:21785161 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of HSPD1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HSPD1 mRNA
CTD PMID:12097258, PMID:21785161 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HSPE1 mRNA CTD PMID:12097258 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of HSPG2 mRNA CTD PMID:21785161 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ICAM1 mRNA CTD PMID:12097258 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ID3 mRNA CTD PMID:12376462 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ier5 immediate early response 5 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide]; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with chrysarobin]; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Okadaic Acid]; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:10365914 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IGF2 mRNA CTD PMID:19480007 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igsf10 immunoglobulin superfamily, member 10 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IGSF10 mRNA CTD PMID:19480007 NCBI chr 2:149,535,199...149,564,180
Ensembl chr 2:149,533,151...149,564,113
JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IL10 protein
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IL10 protein]
CTD PMID:31926054 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A multiple interactions ISO IL12A results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:22359662 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions ISO IL17RA results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:22359662 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL1B protein
tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL1B protein]
CTD PMID:24995432 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL1RL1 protein
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IL1RL1 mRNA
CTD PMID:19480007, PMID:20025956 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IL2 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein]
CTD PMID:8931739, PMID:25770929 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il33 interleukin 33 increases expression EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL33 mRNA CTD PMID:19480007, PMID:27869817 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4r interleukin 4 receptor multiple interactions
increases expression
ISO AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL4RA] CTD PMID:27869817 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides promotes the reaction [[REL protein binds to NFKB1 protein] which binds to IL6 promoter]]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to IL6 promoter]]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of IL6 mRNA; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with ursolic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; ursolic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL6 protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL6 protein]
CTD PMID:14678569, PMID:20043298, PMID:23835587, PMID:24995432, PMID:27891153, PMID:31926054 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig1 insulin induced gene 1 affects expression
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of INSIG1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of INSIG1 mRNA
CTD PMID:12376462, PMID:21785161 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgb6 integrin subunit beta 6 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ITGB6 mRNA CTD PMID:19480007 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Ivns1abp influenza virus NS1A binding protein affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of IVNS1ABP mRNA CTD PMID:21785161 NCBI chr13:68,702,970...68,722,472
Ensembl chr13:68,702,820...68,722,472
JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of JCHAIN mRNA CTD PMID:19480007 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased expression of JUN protein
[Glucaric Acid co-treated with resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with ursolic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; ursolic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of JUN protein modified form
CTD PMID:20025956, PMID:22406437, PMID:23835587 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KEAP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KEAP1 protein
tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of KEAP1 mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of KEAP1 protein]
CTD PMID:24995432 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif1a kinesin family member 1A increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KIF1A mRNA CTD PMID:21527772 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of KIT protein CTD PMID:24576726 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kitlg KIT ligand increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KITLG mRNA CTD PMID:24576726 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of KLF10 mRNA CTD PMID:12097258 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Kng2 kininogen 2 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KNG1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of KNG2 mRNA
CTD PMID:19480007, PMID:22248470 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt19 keratin 19 increases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT19 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KRT19 protein
CTD PMID:22248470 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt5 keratin 5 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KRT5 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT5 mRNA
CTD PMID:12376462, PMID:19480007, PMID:22248470 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Krt8 keratin 8 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KRT8 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT8 protein
CTD PMID:22248470 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Krt80 keratin 80 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr 7:142,995,715...143,015,932
Ensembl chr 7:142,994,119...143,016,040
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LAMC2 mRNA CTD PMID:21527772 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LCK mRNA CTD PMID:19480007 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lgals3 galectin 3 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of LGALS3 mRNA CTD PMID:21785161 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals7 galectin 7 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 1:87,044,823...87,047,223
Ensembl chr 1:87,045,335...87,047,223
JBrowse link
G Limd1 LIM domains containing 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LIMD1 mRNA CTD PMID:19480007 NCBI chr 8:132,553,218...132,598,826
Ensembl chr 8:132,553,218...132,598,812
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of LIN7A mRNA CTD PMID:12376462 NCBI chr 7:49,429,613...49,627,835
Ensembl chr 7:49,385,705...49,656,856
JBrowse link
G Lmna lamin A/C multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of LMNA protein CTD PMID:22248470 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lpl lipoprotein lipase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of LPL mRNA CTD PMID:12376462 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LSR mRNA CTD PMID:12376462 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link
G Ltc4s leukotriene C4 synthase increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LTC4S mRNA CTD PMID:19480007 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
JBrowse link
G Ly6e lymphocyte antigen 6 family member E affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of LY6E mRNA CTD PMID:21785161 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of LYPD1 mRNA CTD PMID:19480007 NCBI chr13:42,219,884...42,263,024
Ensembl chr13:42,219,887...42,263,024
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of LYVE1 mRNA CTD PMID:19480007 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Maea macrophage erythroblast attacher, E3 ubiquitin ligase affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of MAEA mRNA CTD PMID:21785161 NCBI chr14:82,664,248...82,697,673
Ensembl chr14:82,664,249...82,697,673
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MAFB mRNA CTD PMID:19480007 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein] CTD PMID:22760862 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein] CTD PMID:22760862 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mat2a methionine adenosyltransferase 2A affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of MAT2A mRNA CTD PMID:21785161 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MCM3 protein CTD PMID:20025956 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MDH2 mRNA CTD PMID:12376462 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MDM2 mRNA
[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MDM2 mRNA]; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MDM2 mRNA]; theaflavin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MDM2 mRNA]
CTD PMID:23717041 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Megf6 multiple EGF-like-domains 6 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MEGF6 mRNA CTD PMID:19480007 NCBI chr 5:171,588,901...171,620,947
Ensembl chr 5:171,472,273...171,620,947
JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MGARP mRNA CTD PMID:19480007 NCBI chr 2:140,444,963...140,453,719
Ensembl chr 2:140,444,965...140,453,107
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:12663516 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgp matrix Gla protein increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MGP mRNA CTD PMID:12376462 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mif macrophage migration inhibitory factor increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MIF mRNA CTD PMID:12376462 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir3545 microRNA 3545 affects expression
multiple interactions
increases methylation
ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of MIR203 mRNA
Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the expression of MIR203 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of MIR203 promoter]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the expression of MIR203 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of MIR203 promoter]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the expression of MIR203 mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of MIR203 promoter]
CTD PMID:24792773 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Misp3 MISP family member 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MISP3 mRNA CTD PMID:19480007 NCBI chr19:25,132,089...25,135,041
Ensembl chr19:25,132,094...25,134,055
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP 9,10-Dimethyl-1,2-benzanthracene promotes the reaction [Estradiol results in increased expression of MKI67 mRNA]; [Estradiol co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of MKI67 protein; Plant Preparations inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [Estradiol results in increased expression of MKI67 mRNA]] CTD PMID:16891317, PMID:26945725 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlf2 myeloid leukemia factor 2 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of MLF2 mRNA CTD PMID:21785161 NCBI chr 4:157,452,578...157,457,254
Ensembl chr 4:157,452,607...157,457,249
JBrowse link
G Mme membrane metallo-endopeptidase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MME mRNA CTD PMID:19480007 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP12 mRNA CTD PMID:19480007 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP13 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP13 protein CTD PMID:19480007 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MMP14 mRNA CTD PMID:19480007 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression
increases expression
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MMP7 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP7 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP7 protein
CTD PMID:19480007 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects expression
multiple interactions
increases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of MMP9 mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of MMP9 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of MMP9 protein; Resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP9 protein]
CTD PMID:12208745, PMID:21785161, PMID:31332895 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with cumene hydroperoxide] results in increased activity of MPO protein CTD PMID:14972014 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MR1 mRNA CTD PMID:21527772 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of COX1 mRNA CTD PMID:12376462 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MT1 mRNA CTD PMID:19480007 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MTO1 mRNA CTD PMID:19480007 NCBI chr 8:85,807,703...85,832,263
Ensembl chr 8:85,808,125...85,831,937
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression
increases expression
ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MTOR protein modified form
9,10-Dimethyl-1,2-benzanthracene results in increased expression of MTOR protein modified form
CTD PMID:21785161 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of MUC1 mRNA CTD PMID:19480007 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of MYC mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of MYC protein; Butyric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC protein]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of MYC protein]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC protein]; Niacinamide affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC mRNA]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC protein
CTD PMID:20537511, PMID:24792773, PMID:29663660 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh9 myosin, heavy chain 9 increases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYH9 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of MYH9 protein
CTD PMID:22248470 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G Ncmap noncompact myelin associated protein increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NCMAP mRNA CTD PMID:19480007 NCBI chr 5:153,729,250...153,737,161
Ensembl chr 5:153,729,250...153,737,161
JBrowse link
G Nell1 neural EGFL like 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NELL1 mRNA CTD PMID:19480007 NCBI chr 1:105,348,577...106,218,970
Ensembl chr 1:105,349,069...106,218,958
JBrowse link
G Neto2 neuropilin and tolloid like 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NETO2 mRNA CTD PMID:21527772 NCBI chr19:22,450,579...22,486,530
Ensembl chr19:22,450,030...22,486,531
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
increases activity
multiple interactions
decreases expression
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of NFE2L2 protein
9,10-Dimethyl-1,2-benzanthracene results in increased activity of NFE2L2 protein
tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFE2L2 mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFE2L2 protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFE2L2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFE2L2 protein
CTD PMID:22406437, PMID:24995432, PMID:30114225 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides promotes the reaction [[REL protein binds to NFKB1 protein] which binds to IL6 promoter]]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to IL6 promoter]]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein; [ursolic acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein] CTD PMID:14678569, PMID:23835587 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO
EXP
[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of NFKBIA mRNA
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NFKBIA mRNA]
CTD PMID:20043298, PMID:31926054 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nid1 nidogen 1 affects expression
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of NID1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NID1 mRNA
CTD PMID:19480007, PMID:21785161 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nipsnap2 nipsnap homolog 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NIPSNAP2 mRNA CTD PMID:21785161 NCBI chr12:30,527,540...30,566,090
Ensembl chr12:30,527,540...30,566,032
JBrowse link
G Nkg7 natural killer cell granule protein 7 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NKG7 mRNA CTD PMID:19480007 NCBI chr 1:98,492,873...98,493,940
Ensembl chr 1:98,492,828...98,493,978
JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of NLRP5 mRNA CTD PMID:21785161 NCBI chr 1:71,452,184...71,490,915
Ensembl chr 1:71,453,798...71,486,790
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of NOS2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NOS2 protein
[Maxepa co-treated with Calcitriol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NOS2 mRNA]; citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NOS2 protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NOS2 protein]
[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein]
CTD PMID:20043298, PMID:20599847, PMID:24995432, PMID:31926054 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nptx1 neuronal pentraxin 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NPTX1 mRNA CTD PMID:19480007 NCBI chr10:108,682,637...108,691,592
Ensembl chr10:108,682,638...108,691,367
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
multiple interactions
decreases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased activity of NQO1 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of NQO1 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of NQO1 protein; Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of NQO1 protein]; Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NQO1 mRNA]
tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NQO1 mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NQO1 protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NQO1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NQO1 protein
resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of NQO1 protein]
CTD PMID:18694800, PMID:24995432, PMID:25697376 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NR2F1 mRNA CTD PMID:19480007 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of NR4A1 mRNA CTD PMID:27891153 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of NSDHL mRNA CTD PMID:21785161 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NSMF mRNA CTD PMID:12376462 NCBI chr 3:2,262,173...2,270,996
Ensembl chr 3:2,262,253...2,270,995
JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of NTF3 mRNA CTD PMID:19480007 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of OGG1 mRNA
Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of OGG1 mRNA]
CTD PMID:25697376 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Ogn osteoglycin decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of OGN mRNA CTD PMID:19480007 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359
JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of OLFML3 protein CTD PMID:22248470 NCBI chr 2:206,219,419...206,222,248
Ensembl chr 2:206,219,419...206,222,248
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ORM1 protein CTD PMID:20025956 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 affects expression
multiple interactions
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of PABPC1 mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of PABPC1 protein
CTD PMID:21785161, PMID:22248470 NCBI chr 7:75,409,581...75,421,874
Ensembl chr 7:75,409,581...75,422,268
JBrowse link
G Padi4 peptidyl arginine deiminase 4 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PADI4 mRNA CTD PMID:12376462 NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PAPSS2 mRNA CTD PMID:19480007 NCBI chr 1:251,145,264...251,230,716
Ensembl chr 1:251,145,253...251,230,715
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression
multiple interactions
increases expression
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PARP1 mRNA
9,10-Dimethyl-1,2-benzanthracene promotes the reaction [A gene mutant form results in increased expression of PARP1 mRNA]; 9,10-Dimethyl-1,2-benzanthracene promotes the reaction [A gene mutant form results in increased expression of PARP1 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of PARP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PARP1 protein
CTD PMID:23969067, PMID:25448685 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein; [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA]; [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA]; [resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]; Masoprocol affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; Tacrolimus affects the reaction [Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA protein
mithramycin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA protein]
9,10-Dimethyl-1,2-benzanthracene promotes the reaction [Estradiol results in increased expression of PCNA mRNA]; Plant Preparations inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [Estradiol results in increased expression of PCNA mRNA]]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA protein]
CTD PMID:20043298, PMID:20103723, PMID:22248470, PMID:25770929, PMID:26945725, PMID:27091720, PMID:29663660 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcp4 Purkinje cell protein 4 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCP4 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCP4 protein CTD PMID:19480007 NCBI chr11:36,851,035...36,912,272
Ensembl chr11:36,851,038...36,912,229
JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PDGFA mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PDGFA protein CTD PMID:12376462 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of PDIA3 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of PDIA3 protein
CTD PMID:22248470 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PEBP1 mRNA CTD PMID:12376462 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Penk proenkephalin decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PENK mRNA CTD PMID:19480007 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pfkm phosphofructokinase, muscle increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PFKM mRNA CTD PMID:19502547 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of PGLYRP1 mRNA CTD PMID:21785161 NCBI chr 1:79,790,879...79,796,064
Ensembl chr 1:79,790,705...79,796,111
JBrowse link
G Phb prohibitin increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PHB mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PHB protein CTD PMID:12376462 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PHEX protein CTD PMID:20025956 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of PHLDA3 mRNA CTD PMID:21785161 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A multiple interactions
increases mutagenesis
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of and results in decreased activity of PIGA protein; [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein
9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of PIGA; 9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of PIGA gene
CTD PMID:19965957, PMID:20202993, PMID:22923490 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PIK3R5 protein CTD PMID:20025956 NCBI chr10:55,013,686...55,078,986
Ensembl chr10:55,013,703...55,080,421
JBrowse link
G Pitx1 paired-like homeodomain 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PITX1 mRNA CTD PMID:19480007 NCBI chr17:8,873,184...8,884,428
Ensembl chr17:8,878,270...8,884,423
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plk2 polo-like kinase 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PLK2 mRNA CTD PMID:12376462 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Pnisr PNN interacting serine and arginine rich protein increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PNISR mRNA CTD PMID:19480007 NCBI chr 5:35,991,028...36,017,952
Ensembl chr 5:35,991,068...36,017,944
JBrowse link
G Polm DNA polymerase mu increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of POLM mRNA CTD PMID:19480007 NCBI chr14:86,069,378...86,079,327
Ensembl chr14:86,069,016...86,078,954
JBrowse link
G Polr2a RNA polymerase II subunit A multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of POLR2A mRNA CTD PMID:27891153 NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP POMC protein promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] CTD PMID:7588239 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases abundance
ISO POR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]
POR protein results in decreased abundance of 9,10-Dimethyl-1,2-benzanthracene
CTD PMID:22595614 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of PPP1CB mRNA CTD PMID:21785161 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta decreases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PPP2R1B mRNA CTD PMID:19502547 NCBI chr 8:55,279,278...55,311,768
Ensembl chr 8:55,279,373...55,301,320
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PPP2R2B mRNA CTD PMID:19480007 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prdm1 PR/SET domain 1 decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PRDM1 mRNA
AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA]
CTD PMID:20562217 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prdm6 PR/SET domain 6 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PRDM6 mRNA CTD PMID:19480007 NCBI chr18:48,433,747...48,538,834
Ensembl chr18:48,434,652...48,538,023
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PRDX2 protein CTD PMID:20045496 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO PRKCB protein inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; PRKCB protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] CTD PMID:10037446 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions
decreases expression
increases expression
ISO 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [A gene mutant form results in decreased expression of PRKDC mRNA]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PRKDC mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of PRKDC protein
CTD PMID:25448685 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Prl prolactin increases metabolic processing
increases secretion
multiple interactions
EXP PRL protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene results in increased secretion of PRL protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Estradiol] results in increased secretion of PRL protein; [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] affects the metabolism of 9,10-Dimethyl-1,2-benzanthracene
CTD PMID:3141044, PMID:8674863 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Procr protein C receptor increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTBP1 mRNA CTD PMID:12376462 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718
JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions
increases response to substance
ISO celecoxib inhibits the reaction [PTGER1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene]; PTGS2 gene mutant form inhibits the reaction [PTGER1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene] CTD PMID:21739481 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of PTGS2 protein; [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 mRNA]; [resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 mRNA]; [ursolic acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; amarogentin inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Plant Extracts inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of PTGS2 protein]; PTGS2 gene mutant form inhibits the reaction [PTGER1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene]; resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; theaflavin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 mRNA]; ursolic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 protein
[Estradiol co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein; citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 protein]
CTD PMID:12208745, PMID:16517061, PMID:16891317, PMID:20043298, PMID:21739481, PMID:23717041, PMID:23835587, PMID:24995432, PMID:31926054 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptms parathymosin affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of PTMS mRNA CTD PMID:21785161 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTPN22 mRNA CTD PMID:19480007 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTPRCAP mRNA CTD PMID:19480007 NCBI chr 1:219,403,970...219,406,129
Ensembl chr 1:219,403,970...219,406,128
JBrowse link
G Rab12 RAB12, member RAS oncogene family affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of RAB12 mRNA CTD PMID:21785161 NCBI chr 9:114,683,985...114,709,613
Ensembl chr 9:114,684,039...114,709,546
JBrowse link
G Rad51 RAD51 recombinase increases expression
multiple interactions
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 mRNA
A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 protein]; A gene mutant form inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 mRNA]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51 protein
CTD PMID:23969067, PMID:25448685 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAD51AP1 protein CTD PMID:20025956 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein] CTD PMID:22760862 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rag1 recombination activating 1 multiple interactions ISO [CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of RAG1 mRNA CTD PMID:27891153 NCBI chr 3:91,206,394...91,217,491
Ensembl chr 3:91,206,394...91,217,491
JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RAN mRNA CTD PMID:12376462 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Rarres2 retinoic acid receptor responder 2 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of RARRES2 mRNA CTD PMID:19480007 NCBI chr 4:78,205,809...78,208,956
Ensembl chr 4:78,205,812...78,208,767
JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RBP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RBP1 protein CTD PMID:12376462 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides promotes the reaction [[REL protein binds to NFKB1 protein] which binds to IL6 promoter]] CTD PMID:14678569 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to IL6 promoter]]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein]
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RELA protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RELA mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RELA protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of RELA mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RELA protein
CTD PMID:14678569, PMID:20043298, PMID:24995432, PMID:31926054 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rerg RAS-like, estrogen-regulated, growth-inhibitor decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of RERG mRNA CTD PMID:19480007 NCBI chr 4:171,069,161...171,176,678
Ensembl chr 4:171,069,191...171,176,581
JBrowse link
G RGD1562107 similar to class-alpha glutathione S-transferase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of RGD1562107 mRNA CTD PMID:19480007 NCBI chr 9:27,311,229...27,324,452
Ensembl chr 9:27,311,886...27,324,158
JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr11:34,557,679...34,565,776
Ensembl chr11:34,557,679...34,565,776
JBrowse link
G Rpl6 ribosomal protein L6 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RPL6 mRNA CTD PMID:12376462 NCBI chr12:40,877,578...40,882,032
Ensembl chr12:40,877,613...40,881,124
JBrowse link
G Rps6 ribosomal protein S6 decreases expression
increases expression
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of RPS6 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of RPS6 mRNA
CTD PMID:12097258 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rpsa ribosomal protein SA increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RPSA protein CTD PMID:22248470 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO 9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G S100a8 S100 calcium binding protein A8 affects expression
multiple interactions
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene affects the expression of S100A8 mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of S100A8 protein
CTD PMID:21785161, PMID:22248470 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of S1PR1 mRNA CTD PMID:12376462 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SCARB1 mRNA CTD PMID:12376462 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SCD mRNA CTD PMID:12097258, PMID:12376462 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sdc4 syndecan 4 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of SDC4 mRNA CTD PMID:21785161 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sdcbp syndecan binding protein affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of SDCBP mRNA CTD PMID:21785161 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485
JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of SEC23A mRNA CTD PMID:21785161 NCBI chr 6:80,059,742...80,107,340
Ensembl chr 6:80,060,916...80,107,236
JBrowse link
G Selenop selenoprotein P decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SELENOP mRNA CTD PMID:12376462 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Sfn stratifin increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SLC12A2 mRNA CTD PMID:12376462 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc13a3 solute carrier family 13 member 3 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SLC13A3 mRNA CTD PMID:19480007 NCBI chr 3:162,084,336...162,147,398
Ensembl chr 3:162,084,315...162,147,393
JBrowse link
G Slc16a3 solute carrier family 16 member 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SLC16A3 mRNA CTD PMID:19480007 NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SLC1A3 mRNA CTD PMID:19480007 NCBI chr 2:57,860,881...57,935,363
Ensembl chr 2:57,860,834...57,935,363
JBrowse link
G Slc25a10 solute carrier family 25 member 10 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SLC25A10 mRNA CTD PMID:12376462 NCBI chr10:109,665,682...109,674,782
Ensembl chr10:109,665,682...109,673,143
JBrowse link
G Slc38a4 solute carrier family 38, member 4 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SLC38A4 mRNA CTD PMID:19480007 NCBI chr 7:138,459,576...138,512,952
Ensembl chr 7:138,459,504...138,512,952
JBrowse link
G Slc7a3 solute carrier family 7 member 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SLC7A3 mRNA CTD PMID:19480007 NCBI chr  X:70,972,767...70,979,466
Ensembl chr  X:70,972,765...70,978,952
JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SNAI1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SNAI1 protein CTD PMID:29663660 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of SNRNP70 mRNA CTD PMID:21785161 NCBI chr 1:101,367,470...101,388,153
Ensembl chr 1:101,367,471...101,388,129
JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SOD1 mRNA CTD PMID:24576726 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO
EXP
[[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]; [[[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]] which results in decreased expression of SOD2 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of SOD2 mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in decreased expression of and results in decreased activity of SOD2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in decreased expression of SOD2 mRNA; SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene]
CTD PMID:11507057, PMID:22009531, PMID:24576726 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases expression
ISO [[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]; [[[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]] which results in decreased expression of SOD2 mRNA; SP1 protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTNNB1 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of SP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SP1 protein
CTD PMID:22009531, PMID:29663660 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sparcl1 SPARC like 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SPARCL1 mRNA CTD PMID:19480007 NCBI chr14:6,994,261...7,025,309
Ensembl chr14:6,994,190...7,025,308
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SPINK5 mRNA CTD PMID:19480007 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
multiple interactions
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of SPP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SPP1 protein
[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of SPP1 mRNA
CTD PMID:19480007, PMID:27891153 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SRSF5 mRNA CTD PMID:21785161 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G Stat4 signal transducer and activator of transcription 4 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of STAT4 mRNA CTD PMID:19480007 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of STAT5A mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of STAT5A protein CTD PMID:12376462 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stk3 serine/threonine kinase 3 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of STK3 mRNA CTD PMID:21785161 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812
JBrowse link
G Stmn1 stathmin 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of STMN1 mRNA CTD PMID:12376462 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Stmn3 stathmin 3 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of STMN3 mRNA CTD PMID:21527772 NCBI chr 3:176,808,016...176,816,108
Ensembl chr 3:176,808,017...176,816,162
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SULT1A1 mRNA CTD PMID:19480007 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of SUMO3 mRNA CTD PMID:21785161 NCBI chr20:11,726,488...11,737,050
Ensembl chr20:11,726,497...11,737,050
JBrowse link
G Taf15 TATA-box binding protein associated factor 15 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of TAF15 mRNA CTD PMID:21785161 NCBI chr10:70,689,863...70,721,892
Ensembl chr10:70,689,863...70,721,892
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TAF9B mRNA CTD PMID:19480007 NCBI chr  X:77,281,234...77,295,238
Ensembl chr  X:77,281,210...77,295,426
JBrowse link
G Tagln transgelin multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of TAGLN protein CTD PMID:22248470 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tapbp TAP binding protein affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of TAPBP mRNA CTD PMID:21785161 NCBI chr20:5,468,056...5,476,007
Ensembl chr20:5,468,078...5,476,193
JBrowse link
G Tenm4 teneurin transmembrane protein 4 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of TENM4 mRNA CTD PMID:21785161 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923
JBrowse link
G Tesc tescalcin decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TESC mRNA CTD PMID:19480007 NCBI chr12:44,141,258...44,174,701
Ensembl chr12:44,141,422...44,174,583
JBrowse link
G Tfrc transferrin receptor increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TFRC protein CTD PMID:20025956 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Thbs2 thrombospondin 2 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of THBS2 mRNA CTD PMID:19480007 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TIMP1 mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of TIMP1 protein
CTD PMID:12097258, PMID:31332895 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tkt transketolase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TKT mRNA CTD PMID:12376462 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TLE4 mRNA CTD PMID:12376462 NCBI chr 1:231,394,606...231,531,396
Ensembl chr 1:231,393,379...231,530,786
JBrowse link
G Tmem132c transmembrane protein 132C decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TMEM132C mRNA CTD PMID:19480007 NCBI chr12:32,806,372...33,130,746
Ensembl chr12:32,808,022...33,016,885
JBrowse link
G Tmem37 transmembrane protein 37 increases methylation
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased methylation of TMEM37 promoter
[9,10-Dimethyl-1,2-benzanthracene results in increased methylation of TMEM37 promoter] which results in decreased expression of TMEM37 mRNA
CTD PMID:21489049 NCBI chr13:36,094,665...36,101,443
Ensembl chr13:36,094,520...36,101,411
JBrowse link
G Tmpo thymopoietin multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of TMPO protein CTD PMID:22248470 NCBI chr 7:31,847,412...31,872,416
Ensembl chr 7:31,847,410...31,872,423
JBrowse link
G Tmprss6 transmembrane serine protease 6 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TMPRSS6 mRNA CTD PMID:19480007 NCBI chr 7:119,659,323...119,689,953
Ensembl chr 7:119,659,324...119,689,938
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein]
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF protein]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF protein
CTD PMID:20043298, PMID:24995432, PMID:27891153, PMID:31926054 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNFSF9 mRNA CTD PMID:21527772 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
increases expression
increases activity
ISO
EXP
[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA]; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; Butyric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA]; Eugenol promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; Niacinamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 protein]; theaflavin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA]
Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 mRNA]; Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 protein]
9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of TP53 mRNA
9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein
9,10-Dimethyl-1,2-benzanthracene results in increased activity of TP53 protein
[[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]; [[[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]] which results in decreased expression of SOD2 mRNA
CTD PMID:12734332, PMID:18791811, PMID:20043298, PMID:20655369, PMID:22009531, PMID:23717041, PMID:24269759, PMID:25478867, PMID:30101532 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TPM3 mRNA CTD PMID:12376462 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TPPP3 mRNA CTD PMID:19480007 NCBI chr19:37,424,323...37,428,075
Ensembl chr19:37,424,324...37,427,989
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRPC6 mRNA CTD PMID:19480007 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TSLP
AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TSLP]
CTD PMID:27869817 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Tspan8 tetraspanin 8 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of TSPAN8 mRNA CTD PMID:21785161 NCBI chr 7:58,814,805...58,847,564
Ensembl chr 7:58,814,805...58,847,563
JBrowse link
G Tspo translocator protein multiple interactions EXP 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [PK 11195 binds to TSPO protein] CTD PMID:21037200 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Ttc27 tetratricopeptide repeat domain 27 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of TTC27 mRNA CTD PMID:21785161 NCBI chr 6:21,735,833...21,880,008
Ensembl chr 6:21,735,834...21,880,003
JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 9:82,415,599...82,419,918
Ensembl chr 9:82,415,605...82,419,288
JBrowse link
G Tubb2b tubulin, beta 2B class IIb increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TUBB2B mRNA CTD PMID:12376462 NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of TUBB4B protein CTD PMID:22248470 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Twist1 twist family bHLH transcription factor 1 multiple interactions
increases expression
ISO mithramycin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TWIST1 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of TWIST1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TWIST1 protein
CTD PMID:29663660 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Tyr tyrosinase multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of TYR protein CTD PMID:20691676 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Ubd ubiquitin D increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of UBD mRNA CTD PMID:19480007 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of UBE2G1 mRNA CTD PMID:21785161 NCBI chr10:59,173,268...59,254,458
Ensembl chr10:59,173,268...59,254,453
JBrowse link
G Vapb VAMP associated protein B and C affects expression ISO 9,10-Dimethyl-1,2-benzanthracene affects the expression of VAPB mRNA CTD PMID:21785161 NCBI chr 3:171,832,558...171,871,042
Ensembl chr 3:171,832,500...171,868,647
JBrowse link
G Vcp valosin-containing protein multiple interactions
increases expression
EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of VCP protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of VCP protein
CTD PMID:22248470 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions
ISO
EXP
9,10-Dimethyl-1,2-benzanthracene results in increased expression of VEGFA protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of VEGFA protein
9,10-Dimethyl-1,2-benzanthracene results in increased expression of VEGFA mRNA
CTD PMID:19480007, PMID:19502547, PMID:31332895 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of VIM mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of VIM protein CTD PMID:29663660 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vsnl1 visinin-like 1 multiple interactions ISO VSNL1 protein results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:20419170 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023
JBrowse link
G Vwf von Willebrand factor increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of VWF mRNA CTD PMID:19480007 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wdr1 WD repeat domain 1 increases expression
multiple interactions
EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of WDR1 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of WDR1 protein
CTD PMID:22248470 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
G Xdh xanthine dehydrogenase decreases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XDH mRNA CTD PMID:12376462 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor affects response to substance ISO XPA protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene CTD PMID:10755388 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC1 mRNA
[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC1 mRNA]; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC1 mRNA]; epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC1 mRNA]
CTD PMID:23717041 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 decreases expression
multiple interactions
ISO 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC3 mRNA
[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC3 mRNA]; [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC3 mRNA]; epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC3 mRNA]; theaflavin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of XRCC3 mRNA]
CTD PMID:23717041 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 increases expression
multiple interactions
EXP
ISO
9,10-Dimethyl-1,2-benzanthracene results in increased expression of XRCC6 mRNA
A gene mutant form inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of XRCC6 protein]
9,10-Dimethyl-1,2-benzanthracene results in increased expression of XRCC6 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of XRCC6 protein
CTD PMID:23969067, PMID:25448685 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of YWHAZ mRNA CTD PMID:12376462 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ZAP70 mRNA CTD PMID:19480007 NCBI chr 9:43,331,149...43,353,097
Ensembl chr 9:43,331,155...43,353,113
JBrowse link
G Zbp1 Z-DNA binding protein 1 increases expression EXP 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ZBP1 mRNA CTD PMID:19480007 NCBI chr 3:171,276,062...171,292,062
Ensembl chr 3:171,276,062...171,286,537
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 increases expression ISO 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ZEB2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of ZEB2 protein CTD PMID:29663660 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    role 19738
      biological role 19737
        aetiopathogenetic role 18869
          carcinogenic agent 17936
            7,12-dimethyltetraphene 453
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    main group molecular entity 19675
                      s-block molecular entity 19420
                        hydrogen molecular entity 19411
                          hydrides 18460
                            organic hydride 17773
                              organic fundamental parent 17773
                                hydrocarbon 17294
                                  cyclic hydrocarbon 15325
                                    arene 15315
                                      polycyclic arene 14779
                                        ortho-fused polycyclic arene 9610
                                          7,12-dimethyltetraphene 453
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.