CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: alachlor
Accession: CHEBI:2533
browse the term
Definition: An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.
Synonyms: exact_synonym: 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
related_synonym: 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide; Alachlore; Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid; Formula=C14H20ClNO2; InChI=1S/C14H20ClNO2/c1-4-11-7-6-8-12(5-2)14(11)16(10-18-3)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3; InChIKey=XCSGPAVHZFQHGE-UHFFFAOYSA-N; SMILES=CCc1cccc(CC)c1N(COC)C(=O)CCl
xref: Beilstein:2944476; CAS:15972-60-8; HMDB:HMDB0031766; KEGG:C10928; LINCS:LSM-19972
xref_mesh: MESH:C000188
xref: PMID:11807927; PMID:23599414; PPDB:17; Pesticides:alachlor; Reaxys:2944476
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Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions increases activity
ISO
ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel] alachlor results in increased activity of ABCB1 protein
CTD
PMID:18433974
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Ache
acetylcholinesterase
increases activity increases expression
ISO EXP
alachlor results in increased activity of ACHE protein alachlor results in increased expression of ACHE mRNA
CTD
PMID:12419858 PMID:16998629
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Acsm4
acyl-CoA synthetase medium-chain family member 4
affects expression
EXP
alachlor affects the expression of ACSM4 mRNA
CTD
PMID:19425180
NCBI chr 1:174,053,931...174,078,345
Ensembl chr 1:174,053,931...174,078,341
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Adarb1
adenosine deaminase, RNA-specific, B1
increases expression
EXP
alachlor results in increased expression of ADARB1 mRNA
CTD
PMID:12419858
NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
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Adh7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
affects expression
EXP
alachlor affects the expression of ADH7 mRNA
CTD
PMID:19425180
NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
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Aen
apoptosis enhancing nuclease
affects expression
EXP
alachlor affects the expression of AEN mRNA
CTD
PMID:19425180
NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
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Ago2
argonaute RISC catalytic component 2
increases expression
EXP
alachlor results in increased expression of AGO2 mRNA
CTD
PMID:12419858
NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein
CTD
PMID:19883720
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alpl
alkaline phosphatase, biomineralization associated
multiple interactions
ISO
alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA]
CTD
PMID:29149346
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Apod
apolipoprotein D
affects expression
EXP
alachlor affects the expression of APOD mRNA
CTD
PMID:19425180
NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
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Ar
androgen receptor
multiple interactions
ISO
alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [alachlor results in increased activity of AR protein]
CTD
PMID:15064155 PMID:18324785
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arhgap35
Rho GTPase activating protein 35
affects expression
EXP
alachlor affects the expression of ARHGAP35 mRNA
CTD
PMID:19425180
NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
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Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
increases expression
EXP
alachlor results in increased expression of ATIC mRNA
CTD
PMID:12419858
NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
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Bax
BCL2 associated X, apoptosis regulator
increases expression
EXP
alachlor results in increased expression of BAX mRNA
CTD
PMID:12419858
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
increases expression decreases response to substance multiple interactions
ISO
alachlor results in increased expression of BCL2 protein BCL2 protein results in decreased susceptibility to alachlor fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to alachlor]
CTD
PMID:10545406 PMID:12730627
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bin1
bridging integrator 1
increases expression
EXP
alachlor results in increased expression of BIN1 mRNA
CTD
PMID:12419858
NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
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Calca
calcitonin-related polypeptide alpha
increases expression
EXP
alachlor results in increased expression of CALCA mRNA
CTD
PMID:12419858
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Car2
carbonic anhydrase 2
increases expression
EXP
alachlor results in increased expression of CA2 mRNA
CTD
PMID:12419858
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Ccnb1
cyclin B1
increases expression
EXP
alachlor results in increased expression of CCNB1 mRNA
CTD
PMID:12419858
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnd1
cyclin D1
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein
CTD
PMID:19883720
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd2
cyclin D2
increases expression
EXP
alachlor results in increased expression of CCND2 mRNA
CTD
PMID:12419858
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Cd200
Cd200 molecule
increases expression
EXP
alachlor results in increased expression of CD200 mRNA
CTD
PMID:12419858
NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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Cdc123
cell division cycle 123
increases expression
EXP
alachlor results in increased expression of CDC123 mRNA
CTD
PMID:12419858
NCBI chr17:72,459,296...72,502,948
Ensembl chr17:72,459,282...72,503,316
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Cdk1
cyclin-dependent kinase 1
increases expression
EXP
alachlor results in increased expression of CDK1 mRNA
CTD
PMID:12419858
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Ces5a
carboxylesterase 5A
affects expression
EXP
alachlor affects the expression of CES5A mRNA
CTD
PMID:19425180
NCBI chr19:11,469,469...11,499,007
Ensembl chr19:11,469,469...11,499,006
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Cgref1
cell growth regulator with EF hand domain 1
increases expression
EXP
alachlor results in increased expression of CGREF1 mRNA
CTD
PMID:12419858
NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
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Clip2
CAP-GLY domain containing linker protein 2
increases expression
EXP
alachlor results in increased expression of CLIP2 mRNA
CTD
PMID:12419858
NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
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Col11a1
collagen type XI alpha 1 chain
increases expression
EXP
alachlor results in increased expression of COL11A1 mRNA
CTD
PMID:12419858
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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Col5a1
collagen type V alpha 1 chain
increases expression
EXP
alachlor results in increased expression of COL5A1 mRNA
CTD
PMID:12419858
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Col5a2
collagen type V alpha 2 chain
increases expression
EXP
alachlor results in increased expression of COL5A2 mRNA
CTD
PMID:12419858
NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
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Cplx2
complexin 2
increases expression
EXP
alachlor results in increased expression of CPLX2 mRNA
CTD
PMID:12419858
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
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Cpz
carboxypeptidase Z
increases expression
EXP
alachlor results in increased expression of CPZ mRNA
CTD
PMID:12419858
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
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Crabp2
cellular retinoic acid binding protein 2
increases expression
EXP
alachlor results in increased expression of CRABP2 mRNA
CTD
PMID:12419858
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Cxcr4
C-X-C motif chemokine receptor 4
increases expression
EXP
alachlor results in increased expression of CXCR4 mRNA
CTD
PMID:12419858
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
alachlor results in increased expression of CYP1A1 protein
CTD
PMID:11850968
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
alachlor results in increased expression of CYP1A2 protein
CTD
PMID:11850968
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2a3
cytochrome P450, family 2, subfamily a, polypeptide 3
decreases expression
EXP
alachlor results in decreased expression of CYP2A3 protein
CTD
PMID:16698726
NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
multiple interactions
EXP
alachlor results in increased expression of and results in increased activity of CYP2B1 protein
CTD
PMID:11850968
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
alachlor results in increased expression of CYP2B2 protein
CTD
PMID:11850968
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
decreases response to substance
ISO
CYP2B6 protein results in decreased susceptibility to alachlor
CTD
PMID:16277416
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases metabolic processing multiple interactions increases expression
ISO
CYP3A4 protein results in increased metabolism of alachlor [CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide alachlor results in increased expression of CYP3A4 mRNA
CTD
PMID:10475613 PMID:16565514 PMID:18273908
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
alachlor results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:14613717
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
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Defa5
defensin alpha 5
increases expression
EXP
alachlor results in increased expression of DEFA5 mRNA
CTD
PMID:12419858
NCBI chr16:70,342,530...70,344,836
Ensembl chr16:70,342,530...70,344,836
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Dmbt1
deleted in malignant brain tumors 1
increases expression
EXP
alachlor results in increased expression of DMBT1 mRNA
CTD
PMID:12419858
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
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Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
increases expression
EXP
alachlor results in increased expression of EIF4EBP1 mRNA
CTD
PMID:12419858
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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Eln
elastin
increases expression
EXP
alachlor results in increased expression of ELN mRNA
CTD
PMID:12419858
NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
increases expression
EXP
alachlor results in increased expression of ENTPD2 mRNA
CTD
PMID:12419858
NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
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Erp29
endoplasmic reticulum protein 29
increases expression
EXP
alachlor results in increased expression of ERP29 mRNA
CTD
PMID:12419858
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Esr1
estrogen receptor 1
affects binding multiple interactions
ISO
alachlor binds to ESR1 protein [Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; alachlor inhibits the reaction [Estradiol binds to ESR1 protein]
CTD
PMID:9168004 PMID:14579009
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Fdps
farnesyl diphosphate synthase
increases expression
EXP
alachlor results in increased expression of FDPS mRNA
CTD
PMID:12419858
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Fntb
farnesyltransferase, CAAX box, beta
increases expression
EXP
alachlor results in increased expression of FNTB mRNA
CTD
PMID:12419858
NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
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Foxa2
forkhead box A2
increases expression
EXP
alachlor results in increased expression of FOXA2 mRNA
CTD
PMID:12419858
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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Fyn
FYN proto-oncogene, Src family tyrosine kinase
increases expression
EXP
alachlor results in increased expression of FYN mRNA
CTD
PMID:12419858
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
EXP
alachlor results in increased expression of GADD45A mRNA
CTD
PMID:12419858
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
EXP
alachlor results in increased expression of GCLC protein
CTD
PMID:14563481
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gclm
glutamate cysteine ligase, modifier subunit
increases expression
EXP
alachlor results in increased expression of GCLM protein
CTD
PMID:14563481
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Gk
glycerol kinase
affects expression
EXP
alachlor affects the expression of GK mRNA
CTD
PMID:19425180
NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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Gng8
G protein subunit gamma 8
increases expression
EXP
alachlor results in increased expression of GNG8 mRNA
CTD
PMID:12419858
NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371
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Gpx6
glutathione peroxidase 6
increases expression
EXP
alachlor results in increased expression of GPX6 mRNA
CTD
PMID:12419858
NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091
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Gsk3b
glycogen synthase kinase 3 beta
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein
CTD
PMID:19883720
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Hbb
hemoglobin subunit beta
affects binding
EXP
alachlor binds to HBB protein
CTD
PMID:10075819
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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Hdc
histidine decarboxylase
increases expression
EXP
alachlor results in increased expression of HDC mRNA
CTD
PMID:12419858
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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Hmgb2
high mobility group box 2
increases expression
EXP
alachlor results in increased expression of HMGB2 mRNA
CTD
PMID:12419858
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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Hmox1
heme oxygenase 1
increases expression
EXP
alachlor results in increased expression of HMOX1 mRNA
CTD
PMID:12419858
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
increases expression
EXP
alachlor results in increased expression of HNRNPA1 mRNA
CTD
PMID:12419858
NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
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Homer2
homer scaffold protein 2
increases expression
EXP
alachlor results in increased expression of HOMER2 mRNA
CTD
PMID:12419858
NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
EXP
alachlor results in increased expression of HSP90AA1 mRNA alternative form
CTD
PMID:8792849
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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Ifnb1
interferon beta 1
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]
CTD
PMID:15907790 PMID:18177342
NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
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IgG-2a
gamma-2a immunoglobulin heavy chain
affects expression
EXP
alachlor affects the expression of IGG-2A mRNA
CTD
PMID:19425180
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Jchain
joining chain of multimeric IgA and IgM
affects expression
EXP
alachlor affects the expression of JCHAIN mRNA
CTD
PMID:19425180
NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
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Kif3b
kinesin family member 3B
affects expression
EXP
alachlor affects the expression of KIF3B mRNA
CTD
PMID:19425180
NCBI chr 3:141,758,466...141,798,012
Ensembl chr 3:141,758,466...141,797,963
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Klf6
KLF transcription factor 6
increases expression
EXP
alachlor results in increased expression of KLF6 mRNA
CTD
PMID:12419858
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Lgals1
galectin 1
increases expression
EXP
alachlor results in increased expression of LGALS1 mRNA
CTD
PMID:12419858
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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Lgi4
leucine-rich repeat LGI family, member 4
affects expression
EXP
alachlor affects the expression of LGI4 mRNA
CTD
PMID:19425180
NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
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Lxn
latexin
increases expression
EXP
alachlor results in increased expression of LXN mRNA
CTD
PMID:12419858
NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460
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Map3k1
mitogen-activated protein kinase kinase kinase 1
increases expression
EXP
alachlor results in increased expression of MAP3K1 mRNA
CTD
PMID:12419858
NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
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Marcks
myristoylated alanine rich protein kinase C substrate
increases expression
EXP
alachlor results in increased expression of MARCKS mRNA
CTD
PMID:12419858
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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Mcm6
minichromosome maintenance complex component 6
increases expression
EXP
alachlor results in increased expression of MCM6 mRNA
CTD
PMID:12419858
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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Mgat2
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
increases expression
EXP
alachlor results in increased expression of MGAT2 mRNA
CTD
PMID:12419858
NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177
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Mmp2
matrix metallopeptidase 2
increases expression increases activity
EXP
alachlor results in increased expression of MMP2 mRNA alachlor results in increased activity of MMP2 protein
CTD
PMID:12419858 PMID:16178123
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp9
matrix metallopeptidase 9
increases expression
EXP
alachlor results in increased expression of MMP9 mRNA
CTD
PMID:12419858
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Moxd2
monooxygenase, DBH-like 2
affects expression
EXP
alachlor affects the expression of MOXD2 mRNA
CTD
PMID:19425180
NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299
G
Mt3
metallothionein 3
increases expression
EXP
alachlor results in increased expression of MT3 mRNA
CTD
PMID:12419858
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
G
Mvd
mevalonate diphosphate decarboxylase
increases expression
EXP
alachlor results in increased expression of MVD mRNA
CTD
PMID:12419858
NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
G
Myc
MYC proto-oncogene, bHLH transcription factor
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein
CTD
PMID:19883720
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity
ISO
alachlor results in increased activity of NFE2L2 protein
CTD
PMID:20143881
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
G
Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; alachlor inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]
CTD
PMID:15907790 PMID:17015962
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
CTD
PMID:15907790
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Nfkbib
NFKB inhibitor beta
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein]
CTD
PMID:15907790
NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:15907790
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity multiple interactions
ISO EXP
alachlor results in increased activity of NR1I2 protein alachlor binds to and results in increased activity of NR1I2 protein
CTD
PMID:14613717 PMID:16565514 PMID:21115097
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases activity
ISO
alachlor results in increased activity of NR1I3 protein
CTD
PMID:28927721
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
G
Nr3c2
nuclear receptor subfamily 3, group C, member 2
multiple interactions
ISO
alachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; alachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]
CTD
PMID:29149346
NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885
G
Obp2b
odorant binding protein 2B
increases expression
EXP
alachlor results in increased expression of OBP2B mRNA
CTD
PMID:12419858
NCBI chr 3:8,582,074...8,585,258
Ensembl chr 3:8,582,074...8,585,258
G
Or7g31
olfactory receptor family 7 subfamily G member 31
affects expression
EXP
alachlor affects the expression of OR7G2 mRNA
CTD
PMID:19425180
NCBI chr 8:17,056,179...17,057,117
Ensembl chr 8:17,053,661...17,057,239
G
Pcolce
procollagen C-endopeptidase enhancer
increases expression
EXP
alachlor results in increased expression of PCOLCE mRNA
CTD
PMID:12419858
NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
G
Pcsk6
proprotein convertase subtilisin/kexin type 6
increases expression
EXP
alachlor results in increased expression of PCSK6 mRNA
CTD
PMID:12419858
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
G
Pdk2
pyruvate dehydrogenase kinase 2
increases expression
EXP
alachlor results in increased expression of PDK2 mRNA
CTD
PMID:12419858
NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
G
Pgr
progesterone receptor
multiple interactions affects binding
ISO
alachlor inhibits the reaction [Progesterone binds to PGR protein] alachlor binds to PGR protein
CTD
PMID:14579009
NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
G
Phex
phosphate regulating endopeptidase X-linked
increases expression
EXP
alachlor results in increased expression of PHEX mRNA
CTD
PMID:12419858
NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
G
Plp1
proteolipid protein 1
affects expression
EXP
alachlor affects the expression of PLP1 mRNA
CTD
PMID:19425180
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
G
Polr3g
RNA polymerase III subunit G
affects expression
EXP
alachlor affects the expression of POLR3G mRNA
CTD
PMID:19425180
NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125
G
Prph
peripherin
increases expression
EXP
alachlor results in increased expression of PRPH mRNA
CTD
PMID:12419858
NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
G
Ptgds
prostaglandin D2 synthase
affects expression
EXP
alachlor affects the expression of PTGDS mRNA
CTD
PMID:19425180
NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
G
Ptgr1
prostaglandin reductase 1
increases expression
EXP
alachlor results in increased expression of PTGR1 mRNA
CTD
PMID:12419858
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
G
Ptk2b
protein tyrosine kinase 2 beta
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form
CTD
PMID:19883720
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
G
Qdpr
quinoid dihydropteridine reductase
increases expression
EXP
alachlor results in increased expression of QDPR mRNA
CTD
PMID:12419858
NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
G
Qprt
quinolinate phosphoribosyltransferase
affects expression
EXP
alachlor affects the expression of QPRT mRNA
CTD
PMID:19425180
NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
G
Rassf8
Ras association domain family member 8
affects expression
EXP
alachlor affects the expression of RASSF8 mRNA
CTD
PMID:19425180
NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD
PMID:15907790
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rnf138
ring finger protein 138
affects expression
EXP
alachlor affects the expression of RNF138 mRNA
CTD
PMID:19425180
NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
G
RT1-DMa
RT1 class II, locus DMa
increases expression
EXP
alachlor results in increased expression of HLA-DMA mRNA
CTD
PMID:12419858
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
G
S100a8
S100 calcium binding protein A8
increases expression
EXP
alachlor results in increased expression of S100A8 mRNA
CTD
PMID:12419858
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
G
S100a9
S100 calcium binding protein A9
increases expression
EXP
alachlor results in increased expression of S100A9 mRNA
CTD
PMID:12419858
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
G
Scrg1
stimulator of chondrogenesis 1
affects expression
EXP
alachlor affects the expression of SCRG1 mRNA
CTD
PMID:19425180
NCBI chr16:32,760,028...32,788,299
Ensembl chr16:32,760,028...32,788,299
G
Sec24c
SEC24 homolog C, COPII coat complex component
affects expression
EXP
alachlor affects the expression of SEC24C mRNA
CTD
PMID:19425180
NCBI chr15:3,602,460...3,624,524
Ensembl chr15:3,602,460...3,624,422
G
Serpinb11
serpin family B member 11
affects expression
EXP
alachlor affects the expression of SERPINB11 mRNA
CTD
PMID:19425180
NCBI chr13:23,304,775...23,344,604
Ensembl chr13:23,304,456...23,344,604
G
Serpinh1
serpin family H member 1
increases expression
EXP
alachlor results in increased expression of SERPINH1 mRNA
CTD
PMID:12419858
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
G
Slc16a1
solute carrier family 16 member 1
increases expression
EXP
alachlor results in increased expression of SLC16A1 mRNA
CTD
PMID:12419858
NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
G
Slc22a20
solute carrier family 22 member 20
affects expression
EXP
alachlor affects the expression of SLC22A20 mRNA
CTD
PMID:19425180
NCBI chr 1:203,257,374...203,273,848
Ensembl chr 1:203,257,374...203,273,822
G
Slc25a35
solute carrier family 25, member 35
affects expression
EXP
alachlor affects the expression of SLC25A35 mRNA
CTD
PMID:19425180
NCBI chr10:53,672,851...53,677,501
Ensembl chr10:53,673,340...53,698,160
G
Slc4a2
solute carrier family 4 member 2
increases expression
EXP
alachlor results in increased expression of SLC4A2 mRNA
CTD
PMID:12419858
NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
G
Slc6a13
solute carrier family 6 member 13
affects expression
EXP
alachlor affects the expression of SLC6A13 mRNA
CTD
PMID:19425180
NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152
G
Slc7a1
solute carrier family 7 member 1
increases expression
EXP
alachlor results in increased expression of SLC7A1 mRNA
CTD
PMID:12419858
NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849
G
Snrpn
small nuclear ribonucleoprotein polypeptide N
affects expression
EXP
alachlor affects the expression of SNRPN mRNA
CTD
PMID:19425180
NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:111,101,329...111,123,634
G
Snurf
SNRPN upstream open reading frame
affects expression
EXP
alachlor affects the expression of SNURF mRNA
CTD
PMID:19425180
NCBI chr 1:111,101,327...111,123,634
Ensembl chr 1:111,101,329...111,123,634
G
Sox11
SRY-box transcription factor 11
increases expression
EXP
alachlor results in increased expression of SOX11 mRNA
CTD
PMID:12419858
NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
G
Srpx
sushi-repeat-containing protein, X-linked
increases expression
EXP
alachlor results in increased expression of SRPX mRNA
CTD
PMID:12419858
NCBI chr X:12,676,984...12,751,296
Ensembl chr X:12,566,645...12,747,882
G
Tfrc
transferrin receptor
increases expression
EXP
alachlor results in increased expression of TFRC mRNA
CTD
PMID:12419858
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
G
Timp1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
alachlor results in increased expression of TIMP1 mRNA
CTD
PMID:12419858
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Tnc
tenascin C
increases expression
EXP
alachlor results in increased expression of TNC mRNA
CTD
PMID:12419858
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
G
Tnf
tumor necrosis factor
multiple interactions
ISO
alachlor promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD
PMID:15256756
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Top2a
DNA topoisomerase II alpha
increases expression
EXP
alachlor results in increased expression of TOP2A mRNA
CTD
PMID:12419858
NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
G
Tshb
thyroid stimulating hormone subunit beta
increases expression
EXP
alachlor results in increased expression of TSHB protein
CTD
PMID:8812207
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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