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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alachlor
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Accession:CHEBI:2533 term browser browse the term
Definition:An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.
Synonyms:exact_synonym: 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
 related_synonym: 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide;   Alachlore;   Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid;   Formula=C14H20ClNO2;   InChI=1S/C14H20ClNO2/c1-4-11-7-6-8-12(5-2)14(11)16(10-18-3)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3;   InChIKey=XCSGPAVHZFQHGE-UHFFFAOYSA-N;   SMILES=CCc1cccc(CC)c1N(COC)C(=O)CCl
 xref: Beilstein:2944476;   CAS:15972-60-8;   HMDB:HMDB0031766;   KEGG:C10928;   LINCS:LSM-19972
 xref_mesh: MESH:C000188
 xref: PMID:11807927;   PMID:23599414;   PPDB:17;   Pesticides:alachlor;   Reaxys:2944476

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alachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases activity		 ISO ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]
alachlor results in increased activity of ABCB1 protein		 CTD PMID:18433974 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Ache acetylcholinesterase increases activity
increases expression		 ISO
EXP		 alachlor results in increased activity of ACHE protein
alachlor results in increased expression of ACHE mRNA		 CTD PMID:12419858, PMID:16998629 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Acsm4 acyl-CoA synthetase medium-chain family member 4 affects expression EXP alachlor affects the expression of ACSM4 mRNA CTD PMID:19425180 NCBI chr 1:189,432,604...189,458,799
Ensembl chr 1:189,432,604...189,457,048 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression EXP alachlor results in increased expression of ADARB1 mRNA CTD PMID:12419858 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide affects expression EXP alachlor affects the expression of ADH7 mRNA CTD PMID:19425180 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532 		JBrowse link
G Aen apoptosis enhancing nuclease affects expression EXP alachlor affects the expression of AEN mRNA CTD PMID:19425180 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 increases expression EXP alachlor results in increased expression of AGO2 mRNA CTD PMID:12419858 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537 		JBrowse link
G Apod apolipoprotein D affects expression EXP alachlor affects the expression of APOD mRNA CTD PMID:19425180 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301 		JBrowse link
G Ar androgen receptor multiple interactions ISO alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [alachlor results in increased activity of AR protein] CTD PMID:15064155, PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 affects expression EXP alachlor affects the expression of ARHGAP35 mRNA CTD PMID:19425180 NCBI chr 1:78,456,409...78,573,374
Ensembl chr 1:78,456,409...78,573,374 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP alachlor results in increased expression of ATIC mRNA CTD PMID:12419858 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP alachlor results in increased expression of BAX mRNA CTD PMID:12419858 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases response to substance		 ISO alachlor results in increased expression of BCL2 protein
fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to alachlor]		 CTD PMID:10545406, PMID:12730627 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bin1 bridging integrator 1 increases expression EXP alachlor results in increased expression of BIN1 mRNA CTD PMID:12419858 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression EXP alachlor results in increased expression of CALCA mRNA CTD PMID:12419858 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP alachlor results in increased expression of CA2 mRNA CTD PMID:12419858 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029 		JBrowse link
G Ccnb1 cyclin B1 increases expression EXP alachlor results in increased expression of CCNB1 mRNA CTD PMID:12419858 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein CTD PMID:19883720 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP alachlor results in increased expression of CCND2 mRNA CTD PMID:12419858 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207 		JBrowse link
G Cd200 Cd200 molecule increases expression EXP alachlor results in increased expression of CD200 mRNA CTD PMID:12419858 NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196 		JBrowse link
G Cdc123 cell division cycle 123 increases expression EXP alachlor results in increased expression of CDC123 mRNA CTD PMID:12419858 NCBI chr17:76,410,629...76,454,275
Ensembl chr17:76,410,585...76,454,282 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP alachlor results in increased expression of CDK1 mRNA CTD PMID:12419858 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549 		JBrowse link
G Ces5a carboxylesterase 5A affects expression EXP alachlor affects the expression of CES5A mRNA CTD PMID:19425180 NCBI chr19:12,097,529...12,136,579
Ensembl chr19:12,097,632...12,136,240 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP alachlor results in increased expression of CGREF1 mRNA CTD PMID:12419858 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression EXP alachlor results in increased expression of CLIP2 mRNA CTD PMID:12419858 NCBI chr12:25,172,957...25,236,935
Ensembl chr12:25,173,005...25,237,009 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression EXP alachlor results in increased expression of COL11A1 mRNA CTD PMID:12419858 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP alachlor results in increased expression of COL5A1 mRNA CTD PMID:12419858 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP alachlor results in increased expression of COL5A2 mRNA CTD PMID:12419858 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564 		JBrowse link
G Cplx2 complexin 2 increases expression EXP alachlor results in increased expression of CPLX2 mRNA CTD PMID:12419858 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835 		JBrowse link
G Cpz carboxypeptidase Z increases expression EXP alachlor results in increased expression of CPZ mRNA CTD PMID:12419858 NCBI chr14:80,402,946...80,426,203
Ensembl chr14:80,403,001...80,426,245 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression EXP alachlor results in increased expression of CRABP2 mRNA CTD PMID:12419858 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP alachlor results in increased expression of CXCR4 mRNA CTD PMID:12419858 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP alachlor results in increased expression of CYP1A1 protein CTD PMID:11850968 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP1A2 protein CTD PMID:11850968 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression EXP alachlor results in decreased expression of CYP2A3 protein CTD PMID:16698726 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP alachlor results in increased expression of and results in increased activity of CYP2B1 protein CTD PMID:11850968 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP2B2 protein CTD PMID:11850968 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases response to substance ISO CYP2B6 protein results in decreased susceptibility to alachlor CTD PMID:16277416 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP alachlor results in increased expression of CYP3A23-3A1 mRNA CTD PMID:14613717 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136 		JBrowse link
G Defa5 defensin alpha 5 increases expression EXP alachlor results in increased expression of DEFA5 mRNA CTD PMID:12419858 NCBI chr16:75,338,050...75,340,401
Ensembl chr16:75,338,052...75,340,360 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP alachlor results in increased expression of DMBT1 mRNA CTD PMID:12419858 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP alachlor results in increased expression of EIF4EBP1 mRNA CTD PMID:12419858 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248 		JBrowse link
G Eln elastin increases expression EXP alachlor results in increased expression of ELN mRNA CTD PMID:12419858 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP alachlor results in increased expression of ENTPD2 mRNA CTD PMID:12419858 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP alachlor results in increased expression of ERP29 mRNA CTD PMID:12419858 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions		 ISO alachlor binds to ESR1 protein
[Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; alachlor inhibits the reaction [Estradiol binds to ESR1 protein]		 CTD PMID:9168004, PMID:14579009 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP alachlor results in increased expression of FDPS mRNA CTD PMID:12419858 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219 		JBrowse link
G Fntb farnesyltransferase, CAAX box, beta increases expression EXP alachlor results in increased expression of FNTB mRNA CTD PMID:12419858 NCBI chr 6:99,883,959...99,966,988
Ensembl chr 6:99,883,959...99,966,988 		JBrowse link
G Foxa2 forkhead box A2 increases expression EXP alachlor results in increased expression of FOXA2 mRNA CTD PMID:12419858 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression EXP alachlor results in increased expression of FYN mRNA CTD PMID:12419858 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP alachlor results in increased expression of GADD45A mRNA CTD PMID:12419858 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP alachlor results in increased expression of GCLC protein CTD PMID:14563481 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP alachlor results in increased expression of GCLM protein CTD PMID:14563481 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gk glycerol kinase affects expression EXP alachlor affects the expression of GK mRNA CTD PMID:19425180 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864 		JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP alachlor results in increased expression of GNG8 mRNA CTD PMID:12419858 NCBI chr 1:78,818,360...78,822,224
Ensembl chr 1:78,818,404...78,822,224 		JBrowse link
G Gpx6 glutathione peroxidase 6 increases expression EXP alachlor results in increased expression of GPX6 mRNA CTD PMID:12419858 NCBI chr17:45,439,268...45,446,952
Ensembl chr17:45,439,268...45,446,907 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP alachlor binds to HBB protein CTD PMID:10075819 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725 		JBrowse link
G Hdc histidine decarboxylase increases expression EXP alachlor results in increased expression of HDC mRNA CTD PMID:12419858 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619 		JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP alachlor results in increased expression of HMGB2 mRNA CTD PMID:12419858 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP alachlor results in increased expression of HMOX1 mRNA CTD PMID:12419858 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP alachlor results in increased expression of HNRNPA1 mRNA CTD PMID:12419858 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585 		JBrowse link
G Homer2 homer scaffold protein 2 increases expression EXP alachlor results in increased expression of HOMER2 mRNA CTD PMID:12419858 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP alachlor results in increased expression of HSP90AA1 mRNA alternative form CTD PMID:8792849 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:15907790, PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746 		JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain affects expression EXP alachlor affects the expression of IGG-2A mRNA CTD PMID:19425180
G Jchain joining chain of multimeric IgA and IgM affects expression EXP alachlor affects the expression of JCHAIN mRNA CTD PMID:19425180 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542 		JBrowse link
G Kif3b kinesin family member 3B affects expression EXP alachlor affects the expression of KIF3B mRNA CTD PMID:19425180 NCBI chr 3:148,772,937...148,813,342
Ensembl chr 3:148,773,259...148,813,293 		JBrowse link
G Klf6 Kruppel-like factor 6 increases expression EXP alachlor results in increased expression of KLF6 mRNA CTD PMID:12419858 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037 		JBrowse link
G Lgals1 galectin 1 increases expression EXP alachlor results in increased expression of LGALS1 mRNA CTD PMID:12419858 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289 		JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 affects expression EXP alachlor affects the expression of LGI4 mRNA CTD PMID:19425180 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974 		JBrowse link
G Lxn latexin increases expression EXP alachlor results in increased expression of LXN mRNA CTD PMID:12419858 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP alachlor results in increased expression of MAP3K1 mRNA CTD PMID:12419858 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP alachlor results in increased expression of MARCKS mRNA CTD PMID:12419858 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP alachlor results in increased expression of MCM6 mRNA CTD PMID:12419858 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077 		JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression EXP alachlor results in increased expression of MGAT2 mRNA CTD PMID:12419858 NCBI chr 6:91,476,698...91,479,187
Ensembl chr 6:91,476,698...91,479,183 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
increases activity		 EXP alachlor results in increased expression of MMP2 mRNA
alachlor results in increased activity of MMP2 protein		 CTD PMID:12419858, PMID:16178123 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression EXP alachlor results in increased expression of MMP9 mRNA CTD PMID:12419858 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 affects expression EXP alachlor affects the expression of MOXD2 mRNA CTD PMID:19425180 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972 		JBrowse link
G Mt3 metallothionein 3 increases expression EXP alachlor results in increased expression of MT3 mRNA CTD PMID:12419858 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP alachlor results in increased expression of MVD mRNA CTD PMID:12419858 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein CTD PMID:19883720 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO alachlor results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; alachlor inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:15907790, PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:15907790 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:15907790 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15907790 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO
EXP		 alachlor results in increased activity of NR1I2 protein
alachlor binds to and results in increased activity of NR1I2 protein		 CTD PMID:14613717, PMID:16565514, PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO alachlor results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO alachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; alachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695 		JBrowse link
G Obp2a odorant binding protein 2A increases expression EXP alachlor results in increased expression of OBP2B mRNA CTD PMID:12419858 NCBI chr 3:2,908,684...2,913,362
Ensembl chr 3:2,910,083...2,913,362 		JBrowse link
G Olr1144 olfactory receptor 1144 affects expression EXP alachlor affects the expression of OR7G2 mRNA CTD PMID:19425180 NCBI chr 8:19,332,109...19,333,047
Ensembl chr 8:19,332,109...19,333,047 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression EXP alachlor results in increased expression of PCOLCE mRNA CTD PMID:12419858 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 increases expression EXP alachlor results in increased expression of PCSK6 mRNA CTD PMID:12419858 NCBI chr 1:126,749,508...126,947,392
Ensembl chr 1:126,749,508...126,947,392 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP alachlor results in increased expression of PDK2 mRNA CTD PMID:12419858 NCBI chr10:82,838,270...82,852,758
Ensembl chr10:82,839,153...82,852,660 		JBrowse link
G Pgr progesterone receptor multiple interactions
affects binding		 ISO alachlor inhibits the reaction [Progesterone binds to PGR protein]
alachlor binds to PGR protein		 CTD PMID:14579009 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796 		JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression EXP alachlor results in increased expression of PHEX mRNA CTD PMID:12419858 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982 		JBrowse link
G Plp1 proteolipid protein 1 affects expression EXP alachlor affects the expression of PLP1 mRNA CTD PMID:19425180 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348 		JBrowse link
G Polr3g RNA polymerase III subunit G affects expression EXP alachlor affects the expression of POLR3G mRNA CTD PMID:19425180 NCBI chr 2:9,537,642...9,578,551
Ensembl chr 2:9,537,642...9,578,310 		JBrowse link
G Prph peripherin increases expression EXP alachlor results in increased expression of PRPH mRNA CTD PMID:12419858 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197 		JBrowse link
G Ptgds prostaglandin D2 synthase affects expression EXP alachlor affects the expression of PTGDS mRNA CTD PMID:19425180 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP alachlor results in increased expression of PTGR1 mRNA CTD PMID:12419858 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656 		JBrowse link
G Qdpr quinoid dihydropteridine reductase increases expression EXP alachlor results in increased expression of QDPR mRNA CTD PMID:12419858 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase affects expression EXP alachlor affects the expression of QPRT mRNA CTD PMID:19425180 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568 		JBrowse link
G Rassf8 Ras association domain family member 8 affects expression EXP alachlor affects the expression of RASSF8 mRNA CTD PMID:19425180 NCBI chr 4:180,059,020...180,135,924
Ensembl chr 4:180,062,799...180,135,966 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:15907790 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Rnf138 ring finger protein 138 affects expression EXP alachlor affects the expression of RNF138 mRNA CTD PMID:19425180 NCBI chr18:15,146,925...15,167,361 JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression EXP alachlor results in increased expression of HLA-DMA mRNA CTD PMID:12419858 NCBI chr20:3,935,512...3,938,915
Ensembl chr20:5,240,975...5,244,386 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP alachlor results in increased expression of S100A8 mRNA CTD PMID:12419858 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP alachlor results in increased expression of S100A9 mRNA CTD PMID:12419858 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276 		JBrowse link
G Scrg1 stimulator of chondrogenesis 1 affects expression EXP alachlor affects the expression of SCRG1 mRNA CTD PMID:19425180 NCBI chr16:36,127,536...36,161,041
Ensembl chr16:36,125,904...36,161,089 		JBrowse link
G Sec24c SEC24 homolog C, COPII coat complex component affects expression EXP alachlor affects the expression of SEC24C mRNA CTD PMID:19425180 NCBI chr15:4,035,196...4,057,209
Ensembl chr15:4,035,196...4,057,157 		JBrowse link
G Serpinb11 serpin family B member 11 affects expression EXP alachlor affects the expression of SERPINB11 mRNA CTD PMID:19425180 NCBI chr13:27,217,385...27,257,181
Ensembl chr13:27,238,767...27,257,181 		JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP alachlor results in increased expression of SERPINH1 mRNA CTD PMID:12419858 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression EXP alachlor results in increased expression of SLC16A1 mRNA CTD PMID:12419858 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554 		JBrowse link
G Slc22a20 solute carrier family 22 member 20 affects expression EXP alachlor affects the expression of SLC22A20 mRNA CTD PMID:19425180 NCBI chr 1:221,327,608...221,344,367
Ensembl chr 1:221,328,711...221,343,889 		JBrowse link
G Slc25a35 solute carrier family 25, member 35 affects expression EXP alachlor affects the expression of SLC25A35 mRNA CTD PMID:19425180 NCBI chr10:55,554,911...55,559,083
Ensembl chr10:55,555,089...55,559,082 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression EXP alachlor results in increased expression of SLC4A2 mRNA CTD PMID:12419858 NCBI chr 4:7,264,677...7,282,355
Ensembl chr 4:7,264,683...7,281,223 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 affects expression EXP alachlor affects the expression of SLC6A13 mRNA CTD PMID:19425180 NCBI chr 4:153,874,942...153,912,185
Ensembl chr 4:153,874,852...153,912,155 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression EXP alachlor results in increased expression of SLC7A1 mRNA CTD PMID:12419858 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972 		JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N affects expression EXP alachlor affects the expression of SNRPN mRNA CTD PMID:19425180 NCBI chr 1:195,074,328...195,096,460
Ensembl chr 1:195,074,330...195,096,460 		JBrowse link
G Snurf SNRPN upstream reading frame affects expression EXP alachlor affects the expression of SNURF mRNA CTD PMID:19425180 NCBI chr 1:195,074,328...195,096,694
Ensembl chr 1:195,074,330...195,096,694 		JBrowse link
G Sox11 SRY-box transcription factor 11 increases expression EXP alachlor results in increased expression of SOX11 mRNA CTD PMID:12419858 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked increases expression EXP alachlor results in increased expression of SRPX mRNA CTD PMID:12419858 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662 		JBrowse link
G Tfrc transferrin receptor increases expression EXP alachlor results in increased expression of TFRC mRNA CTD PMID:12419858 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP alachlor results in increased expression of TIMP1 mRNA CTD PMID:12419858 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
G Tnc tenascin C increases expression EXP alachlor results in increased expression of TNC mRNA CTD PMID:12419858 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alachlor promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:15256756 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP alachlor results in increased expression of TOP2A mRNA CTD PMID:12419858 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP alachlor results in increased expression of TSHB protein CTD PMID:8812207 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          alachlor 132
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        amine 7602
                                          primary amine 5664
                                            primary arylamine 2955
                                              aniline 2803
                                                anilide 265
                                                  N-phenylacetamide 220
                                                    alachlor 132
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.