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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alachlor
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Accession:CHEBI:2533 term browser browse the term
Definition:An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.
Synonyms:exact_synonym: 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
 related_synonym: 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide;   Alachlore;   Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid;   Formula=C14H20ClNO2;   InChI=1S/C14H20ClNO2/c1-4-11-7-6-8-12(5-2)14(11)16(10-18-3)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3;   InChIKey=XCSGPAVHZFQHGE-UHFFFAOYSA-N;   SMILES=CCc1cccc(CC)c1N(COC)C(=O)CCl
 xref: Beilstein:2944476;   CAS:15972-60-8;   HMDB:HMDB0031766;   KEGG:C10928;   LINCS:LSM-19972
 xref_mesh: MESH:C000188
 xref: PMID:11807927;   PMID:23599414;   PPDB:17;   Pesticides:alachlor;   Reaxys:2944476

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alachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases activity		 ISO ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]
alachlor results in increased activity of ABCB1 protein		 CTD PMID:18433974 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ache acetylcholinesterase increases activity
increases expression		 ISO
EXP		 alachlor results in increased activity of ACHE protein
alachlor results in increased expression of ACHE mRNA		 CTD PMID:12419858 PMID:16998629 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acsm4 acyl-CoA synthetase medium-chain family member 4 affects expression EXP alachlor affects the expression of ACSM4 mRNA CTD PMID:19425180 NCBI chr 1:174,053,931...174,078,345
Ensembl chr 1:174,053,931...174,078,341 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression EXP alachlor results in increased expression of ADARB1 mRNA CTD PMID:12419858 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide affects expression EXP alachlor affects the expression of ADH7 mRNA CTD PMID:19425180 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Aen apoptosis enhancing nuclease affects expression EXP alachlor affects the expression of AEN mRNA CTD PMID:19425180 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 increases expression EXP alachlor results in increased expression of AGO2 mRNA CTD PMID:12419858 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Apod apolipoprotein D affects expression EXP alachlor affects the expression of APOD mRNA CTD PMID:19425180 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Ar androgen receptor multiple interactions ISO alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [alachlor results in increased activity of AR protein] CTD PMID:15064155 PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 affects expression EXP alachlor affects the expression of ARHGAP35 mRNA CTD PMID:19425180 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP alachlor results in increased expression of ATIC mRNA CTD PMID:12419858 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP alachlor results in increased expression of BAX mRNA CTD PMID:12419858 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases response to substance		 ISO alachlor results in increased expression of BCL2 protein
fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to alachlor]		 CTD PMID:10545406 PMID:12730627 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bin1 bridging integrator 1 increases expression EXP alachlor results in increased expression of BIN1 mRNA CTD PMID:12419858 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression EXP alachlor results in increased expression of CALCA mRNA CTD PMID:12419858 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP alachlor results in increased expression of CA2 mRNA CTD PMID:12419858 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Ccnb1 cyclin B1 increases expression EXP alachlor results in increased expression of CCNB1 mRNA CTD PMID:12419858 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein CTD PMID:19883720 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP alachlor results in increased expression of CCND2 mRNA CTD PMID:12419858 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd200 Cd200 molecule increases expression EXP alachlor results in increased expression of CD200 mRNA CTD PMID:12419858 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cdc123 cell division cycle 123 increases expression EXP alachlor results in increased expression of CDC123 mRNA CTD PMID:12419858 NCBI chr17:72,459,296...72,502,948
Ensembl chr17:72,459,282...72,503,316 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP alachlor results in increased expression of CDK1 mRNA CTD PMID:12419858 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Ces5a carboxylesterase 5A affects expression EXP alachlor affects the expression of CES5A mRNA CTD PMID:19425180 NCBI chr19:11,469,469...11,499,007
Ensembl chr19:11,469,469...11,499,006 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP alachlor results in increased expression of CGREF1 mRNA CTD PMID:12419858 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression EXP alachlor results in increased expression of CLIP2 mRNA CTD PMID:12419858 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression EXP alachlor results in increased expression of COL11A1 mRNA CTD PMID:12419858 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP alachlor results in increased expression of COL5A1 mRNA CTD PMID:12419858 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP alachlor results in increased expression of COL5A2 mRNA CTD PMID:12419858 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Cplx2 complexin 2 increases expression EXP alachlor results in increased expression of CPLX2 mRNA CTD PMID:12419858 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855 		JBrowse link
G Cpz carboxypeptidase Z increases expression EXP alachlor results in increased expression of CPZ mRNA CTD PMID:12419858 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression EXP alachlor results in increased expression of CRABP2 mRNA CTD PMID:12419858 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP alachlor results in increased expression of CXCR4 mRNA CTD PMID:12419858 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP alachlor results in increased expression of CYP1A1 protein CTD PMID:11850968 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP1A2 protein CTD PMID:11850968 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression EXP alachlor results in decreased expression of CYP2A3 protein CTD PMID:16698726 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP alachlor results in increased expression of and results in increased activity of CYP2B1 protein CTD PMID:11850968 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP2B2 protein CTD PMID:11850968 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases response to substance ISO CYP2B6 protein results in decreased susceptibility to alachlor CTD PMID:16277416 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
increases expression
multiple interactions		 ISO CYP3A4 protein results in increased metabolism of alachlor
alachlor results in increased expression of CYP3A4 mRNA
[CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide		 CTD PMID:10475613 PMID:16565514 PMID:18273908 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP alachlor results in increased expression of CYP3A23-3A1 mRNA CTD PMID:14613717 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Defa5 defensin alpha 5 increases expression EXP alachlor results in increased expression of DEFA5 mRNA CTD PMID:12419858 NCBI chr16:70,342,530...70,344,836
Ensembl chr16:70,342,530...70,344,836 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP alachlor results in increased expression of DMBT1 mRNA CTD PMID:12419858 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP alachlor results in increased expression of EIF4EBP1 mRNA CTD PMID:12419858 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eln elastin increases expression EXP alachlor results in increased expression of ELN mRNA CTD PMID:12419858 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP alachlor results in increased expression of ENTPD2 mRNA CTD PMID:12419858 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP alachlor results in increased expression of ERP29 mRNA CTD PMID:12419858 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions		 ISO alachlor binds to ESR1 protein
[Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; alachlor inhibits the reaction [Estradiol binds to ESR1 protein]		 CTD PMID:9168004 PMID:14579009 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP alachlor results in increased expression of FDPS mRNA CTD PMID:12419858 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fntb farnesyltransferase, CAAX box, beta increases expression EXP alachlor results in increased expression of FNTB mRNA CTD PMID:12419858 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586 		JBrowse link
G Foxa2 forkhead box A2 increases expression EXP alachlor results in increased expression of FOXA2 mRNA CTD PMID:12419858 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression EXP alachlor results in increased expression of FYN mRNA CTD PMID:12419858 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP alachlor results in increased expression of GADD45A mRNA CTD PMID:12419858 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP alachlor results in increased expression of GCLC protein CTD PMID:14563481 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP alachlor results in increased expression of GCLM protein CTD PMID:14563481 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gk glycerol kinase affects expression EXP alachlor affects the expression of GK mRNA CTD PMID:19425180 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP alachlor results in increased expression of GNG8 mRNA CTD PMID:12419858 NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371 		JBrowse link
G Gpx6 glutathione peroxidase 6 increases expression EXP alachlor results in increased expression of GPX6 mRNA CTD PMID:12419858 NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP alachlor binds to HBB protein CTD PMID:10075819 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hdc histidine decarboxylase increases expression EXP alachlor results in increased expression of HDC mRNA CTD PMID:12419858 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP alachlor results in increased expression of HMGB2 mRNA CTD PMID:12419858 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP alachlor results in increased expression of HMOX1 mRNA CTD PMID:12419858 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP alachlor results in increased expression of HNRNPA1 mRNA CTD PMID:12419858 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Homer2 homer scaffold protein 2 increases expression EXP alachlor results in increased expression of HOMER2 mRNA CTD PMID:12419858 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP alachlor results in increased expression of HSP90AA1 mRNA alternative form CTD PMID:8792849 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:15907790 PMID:18177342 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain affects expression EXP alachlor affects the expression of IGG-2A mRNA CTD PMID:19425180
G Jchain joining chain of multimeric IgA and IgM affects expression EXP alachlor affects the expression of JCHAIN mRNA CTD PMID:19425180 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Kif3b kinesin family member 3B affects expression EXP alachlor affects the expression of KIF3B mRNA CTD PMID:19425180 NCBI chr 3:141,758,466...141,798,012
Ensembl chr 3:141,758,466...141,797,963 		JBrowse link
G Klf6 Kruppel-like factor 6 increases expression EXP alachlor results in increased expression of KLF6 mRNA CTD PMID:12419858 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Lgals1 galectin 1 increases expression EXP alachlor results in increased expression of LGALS1 mRNA CTD PMID:12419858 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 affects expression EXP alachlor affects the expression of LGI4 mRNA CTD PMID:19425180 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874 		JBrowse link
G Lxn latexin increases expression EXP alachlor results in increased expression of LXN mRNA CTD PMID:12419858 NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP alachlor results in increased expression of MAP3K1 mRNA CTD PMID:12419858 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP alachlor results in increased expression of MARCKS mRNA CTD PMID:12419858 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP alachlor results in increased expression of MCM6 mRNA CTD PMID:12419858 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression EXP alachlor results in increased expression of MGAT2 mRNA CTD PMID:12419858 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
increases activity		 EXP alachlor results in increased expression of MMP2 mRNA
alachlor results in increased activity of MMP2 protein		 CTD PMID:12419858 PMID:16178123 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression EXP alachlor results in increased expression of MMP9 mRNA CTD PMID:12419858 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 affects expression EXP alachlor affects the expression of MOXD2 mRNA CTD PMID:19425180 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Mt3 metallothionein 3 increases expression EXP alachlor results in increased expression of MT3 mRNA CTD PMID:12419858 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP alachlor results in increased expression of MVD mRNA CTD PMID:12419858 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein CTD PMID:19883720 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO alachlor results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; alachlor inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:15907790 PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:15907790 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:15907790 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15907790 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO
EXP		 alachlor results in increased activity of NR1I2 protein
alachlor binds to and results in increased activity of NR1I2 protein		 CTD PMID:14613717 PMID:16565514 PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO alachlor results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO alachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; alachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Obp2b odorant binding protein 2B increases expression EXP alachlor results in increased expression of OBP2B mRNA CTD PMID:12419858 NCBI chr 3:8,582,074...8,585,258
Ensembl chr 3:8,582,074...8,585,258 		JBrowse link
G Olr1144 olfactory receptor 1144 affects expression EXP alachlor affects the expression of OR7G2 mRNA CTD PMID:19425180 NCBI chr 8:17,056,179...17,057,117
Ensembl chr 8:17,053,661...17,057,239 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression EXP alachlor results in increased expression of PCOLCE mRNA CTD PMID:12419858 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 increases expression EXP alachlor results in increased expression of PCSK6 mRNA CTD PMID:12419858 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP alachlor results in increased expression of PDK2 mRNA CTD PMID:12419858 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pgr progesterone receptor multiple interactions
affects binding		 ISO alachlor inhibits the reaction [Progesterone binds to PGR protein]
alachlor binds to PGR protein		 CTD PMID:14579009 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression EXP alachlor results in increased expression of PHEX mRNA CTD PMID:12419858 NCBI chr  X:37,607,553...37,856,183
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Plp1 proteolipid protein 1 affects expression EXP alachlor affects the expression of PLP1 mRNA CTD PMID:19425180 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Polr3g RNA polymerase III subunit G affects expression EXP alachlor affects the expression of POLR3G mRNA CTD PMID:19425180 NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125 		JBrowse link
G Prph peripherin increases expression EXP alachlor results in increased expression of PRPH mRNA CTD PMID:12419858 NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136 		JBrowse link
G Ptgds prostaglandin D2 synthase affects expression EXP alachlor affects the expression of PTGDS mRNA CTD PMID:19425180 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP alachlor results in increased expression of PTGR1 mRNA CTD PMID:12419858 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Qdpr quinoid dihydropteridine reductase increases expression EXP alachlor results in increased expression of QDPR mRNA CTD PMID:12419858 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase affects expression EXP alachlor affects the expression of QPRT mRNA CTD PMID:19425180 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
G Rassf8 Ras association domain family member 8 affects expression EXP alachlor affects the expression of RASSF8 mRNA CTD PMID:19425180 NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:15907790 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rnf138 ring finger protein 138 affects expression EXP alachlor affects the expression of RNF138 mRNA CTD PMID:19425180 NCBI chr18:12,291,557...12,315,931 JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression EXP alachlor results in increased expression of HLA-DMA mRNA CTD PMID:12419858 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP alachlor results in increased expression of S100A8 mRNA CTD PMID:12419858 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP alachlor results in increased expression of S100A9 mRNA CTD PMID:12419858 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scrg1 stimulator of chondrogenesis 1 affects expression EXP alachlor affects the expression of SCRG1 mRNA CTD PMID:19425180 NCBI chr16:32,760,028...32,788,299
Ensembl chr16:32,760,028...32,788,299 		JBrowse link
G Sec24c SEC24 homolog C, COPII coat complex component affects expression EXP alachlor affects the expression of SEC24C mRNA CTD PMID:19425180 NCBI chr15:3,602,460...3,624,524
Ensembl chr15:3,602,460...3,624,422 		JBrowse link
G Serpinb11 serpin family B member 11 affects expression EXP alachlor affects the expression of SERPINB11 mRNA CTD PMID:19425180 NCBI chr13:23,304,775...23,344,604
Ensembl chr13:23,304,456...23,344,604 		JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP alachlor results in increased expression of SERPINH1 mRNA CTD PMID:12419858 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression EXP alachlor results in increased expression of SLC16A1 mRNA CTD PMID:12419858 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc22a20 solute carrier family 22 member 20 affects expression EXP alachlor affects the expression of SLC22A20 mRNA CTD PMID:19425180 NCBI chr 1:203,257,374...203,273,848
Ensembl chr 1:203,257,374...203,273,822 		JBrowse link
G Slc25a35 solute carrier family 25, member 35 affects expression EXP alachlor affects the expression of SLC25A35 mRNA CTD PMID:19425180 NCBI chr10:53,672,851...53,677,501
Ensembl chr10:53,673,340...53,698,160 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression EXP alachlor results in increased expression of SLC4A2 mRNA CTD PMID:12419858 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 affects expression EXP alachlor affects the expression of SLC6A13 mRNA CTD PMID:19425180 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression EXP alachlor results in increased expression of SLC7A1 mRNA CTD PMID:12419858 NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N affects expression EXP alachlor affects the expression of SNRPN mRNA CTD PMID:19425180 NCBI chr 1:111,101,327...111,123,400 JBrowse link
G Snurf SNRPN upstream open reading frame affects expression EXP alachlor affects the expression of SNURF mRNA CTD PMID:19425180 NCBI chr 1:111,101,327...111,123,634
Ensembl chr 1:111,101,329...111,123,634 		JBrowse link
G Sox11 SRY-box transcription factor 11 increases expression EXP alachlor results in increased expression of SOX11 mRNA CTD PMID:12419858 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked increases expression EXP alachlor results in increased expression of SRPX mRNA CTD PMID:12419858 NCBI chr  X:12,676,984...12,751,296 JBrowse link
G Tfrc transferrin receptor increases expression EXP alachlor results in increased expression of TFRC mRNA CTD PMID:12419858 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP alachlor results in increased expression of TIMP1 mRNA CTD PMID:12419858 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnc tenascin C increases expression EXP alachlor results in increased expression of TNC mRNA CTD PMID:12419858 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alachlor promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:15256756 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP alachlor results in increased expression of TOP2A mRNA CTD PMID:12419858 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP alachlor results in increased expression of TSHB protein CTD PMID:8812207 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        xenobiotic 18452
          alachlor 134
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        amine 7821
                                          primary amine 5724
                                            primary arylamine 2986
                                              aniline 2824
                                                anilide 272
                                                  N-phenylacetamide 223
                                                    alachlor 134
paths to the root