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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alachlor
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Accession:CHEBI:2533 term browser browse the term
Definition:An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.
Synonyms:exact_synonym: 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
 related_synonym: 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide;   Alachlore;   Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid;   Formula=C14H20ClNO2;   InChI=1S/C14H20ClNO2/c1-4-11-7-6-8-12(5-2)14(11)16(10-18-3)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3;   InChIKey=XCSGPAVHZFQHGE-UHFFFAOYSA-N;   SMILES=CCc1cccc(CC)c1N(COC)C(=O)CCl
 xref: Beilstein:2944476;   CAS:15972-60-8;   HMDB:HMDB0031766;   KEGG:C10928;   LINCS:LSM-19972
 xref_mesh: MESH:C000188
 xref: PMID:11807927;   PMID:23599414;   PPDB:17;   Pesticides:alachlor;   Reaxys:2944476


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alachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases activity
ISO ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]
alachlor results in increased activity of ABCB1 protein
CTD PMID:18433974 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
ISO
EXP
alachlor results in increased activity of ACHE protein
alachlor results in increased expression of ACHE mRNA
CTD PMID:12419858, PMID:16998629 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsm4 acyl-CoA synthetase medium-chain family member 4 affects expression EXP alachlor affects the expression of ACSM4 mRNA CTD PMID:19425180 NCBI chr 1:189,432,604...189,458,799
Ensembl chr 1:189,432,604...189,457,048
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression EXP alachlor results in increased expression of ADARB1 mRNA CTD PMID:12419858 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide affects expression EXP alachlor affects the expression of ADH7 mRNA CTD PMID:19425180 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Aen apoptosis enhancing nuclease affects expression EXP alachlor affects the expression of AEN mRNA CTD PMID:19425180 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Ago2 argonaute RISC catalytic component 2 increases expression EXP alachlor results in increased expression of AGO2 mRNA CTD PMID:12419858 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apod apolipoprotein D affects expression EXP alachlor affects the expression of APOD mRNA CTD PMID:19425180 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Ar androgen receptor multiple interactions ISO alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [alachlor results in increased activity of AR protein] CTD PMID:15064155, PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 affects expression EXP alachlor affects the expression of ARHGAP35 mRNA CTD PMID:19425180 NCBI chr 1:78,456,409...78,573,374
Ensembl chr 1:78,456,409...78,573,374
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP alachlor results in increased expression of ATIC mRNA CTD PMID:12419858 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP alachlor results in increased expression of BAX mRNA CTD PMID:12419858 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases response to substance
ISO alachlor results in increased expression of BCL2 protein
fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to alachlor]
CTD PMID:10545406, PMID:12730627 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bin1 bridging integrator 1 increases expression EXP alachlor results in increased expression of BIN1 mRNA CTD PMID:12419858 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression EXP alachlor results in increased expression of CALCA mRNA CTD PMID:12419858 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP alachlor results in increased expression of CA2 mRNA CTD PMID:12419858 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP alachlor results in increased expression of CCNB1 mRNA CTD PMID:12419858 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein CTD PMID:19883720 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 increases expression EXP alachlor results in increased expression of CCND2 mRNA CTD PMID:12419858 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd200 Cd200 molecule increases expression EXP alachlor results in increased expression of CD200 mRNA CTD PMID:12419858 NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196
JBrowse link
G Cdc123 cell division cycle 123 increases expression EXP alachlor results in increased expression of CDC123 mRNA CTD PMID:12419858 NCBI chr17:76,410,629...76,454,275
Ensembl chr17:76,410,585...76,454,282
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP alachlor results in increased expression of CDK1 mRNA CTD PMID:12419858 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Ces5a carboxylesterase 5A affects expression EXP alachlor affects the expression of CES5A mRNA CTD PMID:19425180 NCBI chr19:12,097,529...12,136,579
Ensembl chr19:12,097,632...12,136,240
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP alachlor results in increased expression of CGREF1 mRNA CTD PMID:12419858 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression EXP alachlor results in increased expression of CLIP2 mRNA CTD PMID:12419858 NCBI chr12:25,172,957...25,236,935
Ensembl chr12:25,173,005...25,237,009
JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression EXP alachlor results in increased expression of COL11A1 mRNA CTD PMID:12419858 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP alachlor results in increased expression of COL5A1 mRNA CTD PMID:12419858 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP alachlor results in increased expression of COL5A2 mRNA CTD PMID:12419858 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Cplx2 complexin 2 increases expression EXP alachlor results in increased expression of CPLX2 mRNA CTD PMID:12419858 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Cpz carboxypeptidase Z increases expression EXP alachlor results in increased expression of CPZ mRNA CTD PMID:12419858 NCBI chr14:80,402,946...80,426,203
Ensembl chr14:80,403,001...80,426,245
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression EXP alachlor results in increased expression of CRABP2 mRNA CTD PMID:12419858 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP alachlor results in increased expression of CXCR4 mRNA CTD PMID:12419858 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP alachlor results in increased expression of CYP1A1 protein CTD PMID:11850968 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP1A2 protein CTD PMID:11850968 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression EXP alachlor results in decreased expression of CYP2A3 protein CTD PMID:16698726 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP alachlor results in increased expression of and results in increased activity of CYP2B1 protein CTD PMID:11850968 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP2B2 protein CTD PMID:11850968 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases response to substance ISO CYP2B6 protein results in decreased susceptibility to alachlor CTD PMID:16277416 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP alachlor results in increased expression of CYP3A23-3A1 mRNA CTD PMID:14613717 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Defa5 defensin alpha 5 increases expression EXP alachlor results in increased expression of DEFA5 mRNA CTD PMID:12419858 NCBI chr16:75,338,050...75,340,401
Ensembl chr16:75,338,052...75,340,360
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP alachlor results in increased expression of DMBT1 mRNA CTD PMID:12419858 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP alachlor results in increased expression of EIF4EBP1 mRNA CTD PMID:12419858 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eln elastin increases expression EXP alachlor results in increased expression of ELN mRNA CTD PMID:12419858 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP alachlor results in increased expression of ENTPD2 mRNA CTD PMID:12419858 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP alachlor results in increased expression of ERP29 mRNA CTD PMID:12419858 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO alachlor binds to ESR1 protein
[Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; alachlor inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:9168004, PMID:14579009 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP alachlor results in increased expression of FDPS mRNA CTD PMID:12419858 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta increases expression EXP alachlor results in increased expression of FNTB mRNA CTD PMID:12419858 NCBI chr 6:99,883,959...99,966,988
Ensembl chr 6:99,883,959...99,966,988
JBrowse link
G Foxa2 forkhead box A2 increases expression EXP alachlor results in increased expression of FOXA2 mRNA CTD PMID:12419858 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression EXP alachlor results in increased expression of FYN mRNA CTD PMID:12419858 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP alachlor results in increased expression of GADD45A mRNA CTD PMID:12419858 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP alachlor results in increased expression of GCLC protein CTD PMID:14563481 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP alachlor results in increased expression of GCLM protein CTD PMID:14563481 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gk glycerol kinase affects expression EXP alachlor affects the expression of GK mRNA CTD PMID:19425180 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP alachlor results in increased expression of GNG8 mRNA CTD PMID:12419858 NCBI chr 1:78,818,360...78,822,224
Ensembl chr 1:78,818,404...78,822,224
JBrowse link
G Gpx6 glutathione peroxidase 6 increases expression EXP alachlor results in increased expression of GPX6 mRNA CTD PMID:12419858 NCBI chr17:45,439,268...45,446,952
Ensembl chr17:45,439,268...45,446,907
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP alachlor binds to HBB protein CTD PMID:10075819 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hdc histidine decarboxylase increases expression EXP alachlor results in increased expression of HDC mRNA CTD PMID:12419858 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP alachlor results in increased expression of HMGB2 mRNA CTD PMID:12419858 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP alachlor results in increased expression of HMOX1 mRNA CTD PMID:12419858 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP alachlor results in increased expression of HNRNPA1 mRNA CTD PMID:12419858 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Homer2 homer scaffold protein 2 increases expression EXP alachlor results in increased expression of HOMER2 mRNA CTD PMID:12419858 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP alachlor results in increased expression of HSP90AA1 mRNA alternative form CTD PMID:8792849 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:15907790, PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain affects expression EXP alachlor affects the expression of IGG-2A mRNA CTD PMID:19425180
G Jchain joining chain of multimeric IgA and IgM affects expression EXP alachlor affects the expression of JCHAIN mRNA CTD PMID:19425180 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
JBrowse link
G Kif3b kinesin family member 3B affects expression EXP alachlor affects the expression of KIF3B mRNA CTD PMID:19425180 NCBI chr 3:148,772,937...148,813,342
Ensembl chr 3:148,773,259...148,813,293
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression EXP alachlor results in increased expression of KLF6 mRNA CTD PMID:12419858 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Lgals1 galectin 1 increases expression EXP alachlor results in increased expression of LGALS1 mRNA CTD PMID:12419858 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 affects expression EXP alachlor affects the expression of LGI4 mRNA CTD PMID:19425180 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
JBrowse link
G Lxn latexin increases expression EXP alachlor results in increased expression of LXN mRNA CTD PMID:12419858 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP alachlor results in increased expression of MAP3K1 mRNA CTD PMID:12419858 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP alachlor results in increased expression of MARCKS mRNA CTD PMID:12419858 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP alachlor results in increased expression of MCM6 mRNA CTD PMID:12419858 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression EXP alachlor results in increased expression of MGAT2 mRNA CTD PMID:12419858 NCBI chr 6:91,476,698...91,479,187
Ensembl chr 6:91,476,698...91,479,183
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
increases activity
EXP alachlor results in increased expression of MMP2 mRNA
alachlor results in increased activity of MMP2 protein
CTD PMID:12419858, PMID:16178123 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression EXP alachlor results in increased expression of MMP9 mRNA CTD PMID:12419858 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 affects expression EXP alachlor affects the expression of MOXD2 mRNA CTD PMID:19425180 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Mt3 metallothionein 3 increases expression EXP alachlor results in increased expression of MT3 mRNA CTD PMID:12419858 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP alachlor results in increased expression of MVD mRNA CTD PMID:12419858 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein CTD PMID:19883720 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO alachlor results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; alachlor inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:15907790, PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:15907790 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:15907790 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15907790 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO
EXP
alachlor results in increased activity of NR1I2 protein
alachlor binds to and results in increased activity of NR1I2 protein
CTD PMID:14613717, PMID:16565514, PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO alachlor results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO alachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; alachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Obp2a odorant binding protein 2A increases expression EXP alachlor results in increased expression of OBP2B mRNA CTD PMID:12419858 NCBI chr 3:2,908,684...2,913,362
Ensembl chr 3:2,910,083...2,913,362
JBrowse link
G Olr1144 olfactory receptor 1144 affects expression EXP alachlor affects the expression of OR7G2 mRNA CTD PMID:19425180 NCBI chr 8:19,332,109...19,333,047
Ensembl chr 8:19,332,109...19,333,047
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression EXP alachlor results in increased expression of PCOLCE mRNA CTD PMID:12419858 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 increases expression EXP alachlor results in increased expression of PCSK6 mRNA CTD PMID:12419858 NCBI chr 1:126,749,508...126,947,392
Ensembl chr 1:126,749,508...126,947,392
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP alachlor results in increased expression of PDK2 mRNA CTD PMID:12419858 NCBI chr10:82,838,270...82,852,758
Ensembl chr10:82,839,153...82,852,660
JBrowse link
G Pgr progesterone receptor multiple interactions
affects binding
ISO alachlor inhibits the reaction [Progesterone binds to PGR protein]
alachlor binds to PGR protein
CTD PMID:14579009 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression EXP alachlor results in increased expression of PHEX mRNA CTD PMID:12419858 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Plp1 proteolipid protein 1 affects expression EXP alachlor affects the expression of PLP1 mRNA CTD PMID:19425180 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348
JBrowse link
G Polr3g RNA polymerase III subunit G affects expression EXP alachlor affects the expression of POLR3G mRNA CTD PMID:19425180 NCBI chr 2:9,537,642...9,578,551
Ensembl chr 2:9,537,642...9,578,310
JBrowse link
G Prph peripherin increases expression EXP alachlor results in increased expression of PRPH mRNA CTD PMID:12419858 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
JBrowse link
G Ptgds prostaglandin D2 synthase affects expression EXP alachlor affects the expression of PTGDS mRNA CTD PMID:19425180 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP alachlor results in increased expression of PTGR1 mRNA CTD PMID:12419858 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Qdpr quinoid dihydropteridine reductase increases expression EXP alachlor results in increased expression of QDPR mRNA CTD PMID:12419858 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284
JBrowse link
G Qprt quinolinate phosphoribosyltransferase affects expression EXP alachlor affects the expression of QPRT mRNA CTD PMID:19425180 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
G Rassf8 Ras association domain family member 8 affects expression EXP alachlor affects the expression of RASSF8 mRNA CTD PMID:19425180 NCBI chr 4:180,059,020...180,135,924
Ensembl chr 4:180,062,799...180,135,966
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:15907790 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rnf138 ring finger protein 138 affects expression EXP alachlor affects the expression of RNF138 mRNA CTD PMID:19425180 NCBI chr18:15,146,925...15,167,361 JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression EXP alachlor results in increased expression of HLA-DMA mRNA CTD PMID:12419858 NCBI chr20:3,935,512...3,938,915
Ensembl chr20:5,240,975...5,244,386
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP alachlor results in increased expression of S100A8 mRNA CTD PMID:12419858 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP alachlor results in increased expression of S100A9 mRNA CTD PMID:12419858 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Scrg1 stimulator of chondrogenesis 1 affects expression EXP alachlor affects the expression of SCRG1 mRNA CTD PMID:19425180 NCBI chr16:36,127,536...36,161,041
Ensembl chr16:36,125,904...36,161,089
JBrowse link
G Sec24c SEC24 homolog C, COPII coat complex component affects expression EXP alachlor affects the expression of SEC24C mRNA CTD PMID:19425180 NCBI chr15:4,035,196...4,057,209
Ensembl chr15:4,035,196...4,057,157
JBrowse link
G Serpinb11 serpin family B member 11 affects expression EXP alachlor affects the expression of SERPINB11 mRNA CTD PMID:19425180 NCBI chr13:27,217,385...27,257,181
Ensembl chr13:27,238,767...27,257,181
JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP alachlor results in increased expression of SERPINH1 mRNA CTD PMID:12419858 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression EXP alachlor results in increased expression of SLC16A1 mRNA CTD PMID:12419858 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc22a20 solute carrier family 22 member 20 affects expression EXP alachlor affects the expression of SLC22A20 mRNA CTD PMID:19425180 NCBI chr 1:221,327,608...221,344,367
Ensembl chr 1:221,328,711...221,343,889
JBrowse link
G Slc25a35 solute carrier family 25, member 35 affects expression EXP alachlor affects the expression of SLC25A35 mRNA CTD PMID:19425180 NCBI chr10:55,554,911...55,559,083
Ensembl chr10:55,555,089...55,559,082
JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression EXP alachlor results in increased expression of SLC4A2 mRNA CTD PMID:12419858 NCBI chr 4:7,264,677...7,282,355
Ensembl chr 4:7,264,683...7,281,223
JBrowse link
G Slc6a13 solute carrier family 6 member 13 affects expression EXP alachlor affects the expression of SLC6A13 mRNA CTD PMID:19425180 NCBI chr 4:153,874,942...153,912,185
Ensembl chr 4:153,874,852...153,912,155
JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression EXP alachlor results in increased expression of SLC7A1 mRNA CTD PMID:12419858 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972
JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N affects expression EXP alachlor affects the expression of SNRPN mRNA CTD PMID:19425180 NCBI chr 1:195,074,328...195,096,460
Ensembl chr 1:195,074,330...195,096,460
JBrowse link
G Snurf SNRPN upstream reading frame affects expression EXP alachlor affects the expression of SNURF mRNA CTD PMID:19425180 NCBI chr 1:195,074,328...195,096,694
Ensembl chr 1:195,074,330...195,096,694
JBrowse link
G Sox11 SRY-box transcription factor 11 increases expression EXP alachlor results in increased expression of SOX11 mRNA CTD PMID:12419858 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked increases expression EXP alachlor results in increased expression of SRPX mRNA CTD PMID:12419858 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
G Tfrc transferrin receptor increases expression EXP alachlor results in increased expression of TFRC mRNA CTD PMID:12419858 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP alachlor results in increased expression of TIMP1 mRNA CTD PMID:12419858 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnc tenascin C increases expression EXP alachlor results in increased expression of TNC mRNA CTD PMID:12419858 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alachlor promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:15256756 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP alachlor results in increased expression of TOP2A mRNA CTD PMID:12419858 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP alachlor results in increased expression of TSHB protein CTD PMID:8812207 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          alachlor 132
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        amine 7602
                                          primary amine 5664
                                            primary arylamine 2955
                                              aniline 2803
                                                anilide 265
                                                  N-phenylacetamide 220
                                                    alachlor 132
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.