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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methyl halides
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Accession:CHEBI:25253 term browser browse the term
Definition:A haloalkane that is methane in which one of the hydrogens is substituted by a halide atom.
Synonyms:xref: PMID:19378995


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bromomethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstt1 glutathione S-transferase theta 1 increases metabolic processing ISO GSTT1 protein results in increased metabolism of methyl bromide CTD PMID:11305778 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
chloromethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation ISO CYP2E1 protein results in increased oxidation of Methyl Chloride CTD PMID:1664256 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions
increases metabolic processing		 ISO GSTT1 protein polymorphism affects the metabolism of and affects the susceptibility to Methyl Chloride
GSTT1 protein results in increased metabolism of Methyl Chloride		 CTD PMID:11218045 PMID:11305778 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
iodomethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity EXP methyl iodide results in decreased activity of DIO1 protein CTD PMID:19519149 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity EXP methyl iodide results in decreased activity of DIO2 protein CTD PMID:19519149 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Fut8 fucosyltransferase 8 decreases activity ISO methyl iodide results in decreased activity of FUT8 protein CTD PMID:12770769 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases alkylation
multiple interactions		 ISO methyl iodide results in increased alkylation of MGMT protein
[methyl iodide results in increased alkylation of MGMT protein] which affects the folding of MGMT protein modified form		 CTD PMID:8823159 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    role 20023
      chemical role 19565
        greenhouse gas 11292
          methane 10324
            halomethane 10308
              methyl halides 6
                bromomethane 1
                chloromethane 2
                fluoromethane 0
                iodomethane 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    main group molecular entity 19959
                      s-block molecular entity 19758
                        hydrogen molecular entity 19764
                          hydrides 19134
                            organic hydride 18675
                              organic fundamental parent 18662
                                hydrocarbon 18400
                                  halohydrocarbon 15409
                                    haloalkane 12099
                                      halomethane 10308
                                        methyl halides 6
                                          bromomethane 1
                                          chloromethane 2
                                          fluoromethane 0
                                          iodomethane 4
paths to the root