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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methoxybenzoic acid
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Accession:CHEBI:25238 term browser browse the term
Definition:Any benzoic acid carrying one or more methoxy substituents.
Synonyms:related_synonym: methoxybenzoic acids


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3,4-dimethoxybenzoic acid 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl ester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO mebeverine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO mebeverine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
dicamba term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases activity EXP Dicamba results in increased activity of ACOX1 protein CTD PMID:7657066 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Dicamba inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Alb albumin multiple interactions EXP [bentazone co-treated with Dicamba] results in increased secretion of ALB protein CTD PMID:25863332 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Dicamba inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
eluxadoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprd1 opioid receptor, delta 1 affects response to substance ISO OPRD1 protein affects the susceptibility to eluxadoline CTD PMID:25261794 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
O-methylsalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
ISO 2-methoxybenzoic acid inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]
2-methoxybenzoic acid results in decreased activity of PTGS2 protein
CTD PMID:12538810 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
vanillic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA] CTD PMID:25794854 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA] CTD PMID:25794854 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA] CTD PMID:25794854 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA] CTD PMID:25794854 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G LOC100912605 olfactory receptor 5D14-like multiple interactions ISO Vanillic Acid analog binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link
G Mir122 microRNA 122 decreases expression ISO Vanillic Acid results in decreased expression of MIR122 mRNA CTD PMID:24165878 NCBI chr18:60,755,285...60,755,369 JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO Vanillic Acid results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Vanillic Acid CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Vanillic Acid CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      chemical role 19351
        donor 18483
          Bronsted acid 18336
            oxoacid 18286
              carbon oxoacid 18164
                carboxylic acid 18153
                  aromatic carboxylic acid 10918
                    benzoic acids 10887
                      methoxybenzoic acid 17
                        2,4,5-Trimethoxybenzoic acid 0
                        2,6-dimethoxybenzoic acid [[amino(pyridin-4-yl)methylidene]amino] ester 0
                        2-[[anilino(oxo)methyl]amino]-4,5-dimethoxybenzoic acid 0
                        2-hydroxy-3-methoxybenzoic acid [2-[2-chloro-5-[ethyl(phenyl)sulfamoyl]anilino]-2-oxoethyl] ester 0
                        2-hydroxy-4-methoxy-6-methylbenzoic acid ethyl ester 0
                        2-hydroxy-4-methoxy-6-methylbenzoic acid methyl ester 0
                        2-hydroxy-4-methoxybenzoic acid (2-methyl-4-thiazolyl)methyl ester 0
                        2-methoxy-4-(methylthio)benzoic acid [2-(cyclopropylamino)-2-oxoethyl] ester 0
                        2-methoxybenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester 0
                        3,4-dimethoxybenzoic acid 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl ester 2
                        3,4-dimethoxybenzoic acid [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                        3,5-dimethoxybenzoic acid + 0
                        3-decaprenyl-4-hydroxy-5-methoxybenzoic acid 0
                        3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid 0
                        3-hydroxy-4-methoxybenzoic acid + 0
                        3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoic acid + 0
                        3-methoxybenzoic acid [[1-amino-2-(4-chlorophenyl)ethylidene]amino] ester 0
                        3-methoxybenzoic acid [[amino-(4-nitrophenyl)methylidene]amino] ester 0
                        3-nonaprenyl-4-hydroxy-5-methoxybenzoic acid 0
                        4,5-dimethoxy-2-[[(2-methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester 0
                        4-O-methylolivetolcarboxylic acid 0
                        4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate 0
                        4-[2-[(2,6-dimethoxyphenyl)-oxomethoxy]-1-oxoethyl]-2,5-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester 0
                        4-acetyloxy-3-methoxybenzoic acid (4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl) ester 0
                        4-amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester 0
                        4-amino-5-chloro-2-methoxybenzoic acid 3-(1-piperidinyl)propyl ester 0
                        4-hydroxy-3-methoxybenzoic acid [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                        4-methoxy-3-[2-phenylethyl-(phenylmethyl)sulfamoyl]benzoic acid 0
                        4-methoxybenzoic acid + 0
                        4-methoxybenzoic acid 2-(4-hydroxyphenyl)ethyl ester 0
                        4-methoxybenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester 0
                        4-methoxybenzoic acid [1-(2-pyrazinyl)ethylideneamino] ester 0
                        4-methoxybenzoic acid [1-(2-thiazolyl)ethylideneamino] ester 0
                        4-methoxybenzoic acid [2-(4-bromophenyl)-4-oxo-3-quinazolinyl] ester 0
                        4-methoxybenzoic acid [2-oxo-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)amino]ethyl] ester 0
                        5-(1,3-benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid 0
                        5-Chlorodivaricatinic acid 0
                        5-Chloropyridin-3-yl 3-methoxybenzoate 0
                        5-Methoxy-3-hydroxyanthranilate 0
                        Convolamine 0
                        Convoline 0
                        Convolvine 0
                        Damascenine 0
                        Divaricatinic acid 0
                        Falaconitine 0
                        Isoevernic acid 0
                        Methylveratrate 0
                        N-Pyruvoyl-5-methoxy-3-hydroxyanthranilate 0
                        O-methylsalicylic acid + 1
                        Phyllalbine 0
                        Rhizonic acid 0
                        SureCN668028 0
                        dicamba 4
                        eluxadoline 1
                        lignin cw compound-192 0
                        macrophomic acid 0
                        methoxysalicylic acid + 0
                        tricamba 0
                        vanillic acid + 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic group 18580
                              organic divalent group 18571
                                organodiyl group 18571
                                  carbonyl group 18479
                                    carbonyl compound 18479
                                      carboxylic acid 18153
                                        aromatic carboxylic acid 10918
                                          benzoic acids 10887
                                            methoxybenzoic acid 17
                                              2,4,5-Trimethoxybenzoic acid 0
                                              2,6-dimethoxybenzoic acid [[amino(pyridin-4-yl)methylidene]amino] ester 0
                                              2-[[anilino(oxo)methyl]amino]-4,5-dimethoxybenzoic acid 0
                                              2-hydroxy-3-methoxybenzoic acid [2-[2-chloro-5-[ethyl(phenyl)sulfamoyl]anilino]-2-oxoethyl] ester 0
                                              2-hydroxy-4-methoxy-6-methylbenzoic acid ethyl ester 0
                                              2-hydroxy-4-methoxy-6-methylbenzoic acid methyl ester 0
                                              2-hydroxy-4-methoxybenzoic acid (2-methyl-4-thiazolyl)methyl ester 0
                                              2-methoxy-4-(methylthio)benzoic acid [2-(cyclopropylamino)-2-oxoethyl] ester 0
                                              2-methoxybenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester 0
                                              3,4-dimethoxybenzoic acid 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl ester 2
                                              3,4-dimethoxybenzoic acid [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                              3,5-dimethoxybenzoic acid + 0
                                              3-decaprenyl-4-hydroxy-5-methoxybenzoic acid 0
                                              3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid 0
                                              3-hydroxy-4-methoxybenzoic acid + 0
                                              3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoic acid + 0
                                              3-methoxybenzoic acid [[1-amino-2-(4-chlorophenyl)ethylidene]amino] ester 0
                                              3-methoxybenzoic acid [[amino-(4-nitrophenyl)methylidene]amino] ester 0
                                              3-nonaprenyl-4-hydroxy-5-methoxybenzoic acid 0
                                              4,5-dimethoxy-2-[[(2-methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester 0
                                              4-O-methylolivetolcarboxylic acid 0
                                              4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate 0
                                              4-[2-[(2,6-dimethoxyphenyl)-oxomethoxy]-1-oxoethyl]-2,5-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester 0
                                              4-acetyloxy-3-methoxybenzoic acid (4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl) ester 0
                                              4-amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester 0
                                              4-amino-5-chloro-2-methoxybenzoic acid 3-(1-piperidinyl)propyl ester 0
                                              4-hydroxy-3-methoxybenzoic acid [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                              4-methoxy-3-[2-phenylethyl-(phenylmethyl)sulfamoyl]benzoic acid 0
                                              4-methoxybenzoic acid + 0
                                              4-methoxybenzoic acid 2-(4-hydroxyphenyl)ethyl ester 0
                                              4-methoxybenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester 0
                                              4-methoxybenzoic acid [1-(2-pyrazinyl)ethylideneamino] ester 0
                                              4-methoxybenzoic acid [1-(2-thiazolyl)ethylideneamino] ester 0
                                              4-methoxybenzoic acid [2-(4-bromophenyl)-4-oxo-3-quinazolinyl] ester 0
                                              4-methoxybenzoic acid [2-oxo-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)amino]ethyl] ester 0
                                              5-(1,3-benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid 0
                                              5-Chlorodivaricatinic acid 0
                                              5-Chloropyridin-3-yl 3-methoxybenzoate 0
                                              5-Methoxy-3-hydroxyanthranilate 0
                                              Convolamine 0
                                              Convoline 0
                                              Convolvine 0
                                              Damascenine 0
                                              Divaricatinic acid 0
                                              Falaconitine 0
                                              Isoevernic acid 0
                                              Methylveratrate 0
                                              N-Pyruvoyl-5-methoxy-3-hydroxyanthranilate 0
                                              O-methylsalicylic acid + 1
                                              Phyllalbine 0
                                              Rhizonic acid 0
                                              SureCN668028 0
                                              dicamba 4
                                              eluxadoline 1
                                              lignin cw compound-192 0
                                              macrophomic acid 0
                                              methoxysalicylic acid + 0
                                              tricamba 0
                                              vanillic acid + 9
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