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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:magnesium atom
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Accession:CHEBI:25107 term browser browse the term
Definition:An alkaline earth metal atom that has formula Mg.
Synonyms:related_synonym: 12Mg;   Formula=Mg;   InChI=1S/Mg;   InChIKey=FYYHWMGAXLPEAU-UHFFFAOYSA-N;   Magnesium;   Mg;   SMILES=[Mg];   magnesio
 xref: CAS:7439-95-4;   DrugBank:DB01378;   Gmelin:16207;   KEGG:C00305
 xref_mesh: MESH:D008274
 xref: WebElements:Mg



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magnesium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
increases activity
EXP [Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; Cadmium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]; Copper inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]; Nickel inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]; Zinc inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] CTD PMID:2900677 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 multiple interactions ISO [Magnesium deficiency co-treated with Phosphates] promotes the reaction [ABCC6 gene mutant form results in increased susceptibility to Warfarin] CTD PMID:23415960 NCBI chr16:16,149,565...16,223,617
Ensembl chr16:16,149,565...16,223,522
JBrowse link
G ADCY5 adenylate cyclase 5 increases activity EXP Magnesium results in increased activity of ADCY5 protein CTD PMID:12065575 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO 1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of AKT1 protein]; iodopravadoline inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of AKT1 protein]]; Wortmannin inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of AKT1 protein]] CTD PMID:30542433 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 multiple interactions ISO Magnesium inhibits the reaction [ALDH1A1 protein affects the oxidation of 9-cis-retinal]; Magnesium inhibits the reaction [ALDH1A1 protein affects the oxidation of Retinaldehyde] CTD PMID:17167544 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member multiple interactions
affects activity
ISO
EXP
Magnesium affects the reaction [NAD binds to ALDH2 protein]
Magnesium promotes the reaction [ALDH2 protein results in increased oxidation of propionaldehyde]
Magnesium affects the activity of ALDH2 protein
CTD PMID:21276780 PMID:23295226 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ANXA1 annexin A1 multiple interactions ISO [Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein; arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein] CTD PMID:20655937 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ATP7B ATPase copper transporting beta increases phosphorylation EXP Magnesium results in increased phosphorylation of ATP7B protein CTD PMID:19405516 NCBI chr13:51,932,669...52,012,130
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with Magnesium deficiency] results in increased expression of BCL2 protein; iodopravadoline inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with Magnesium deficiency] results in increased expression of BCL2 protein]; Wortmannin inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with Magnesium deficiency] results in increased expression of BCL2 protein] CTD PMID:30542433 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression EXP Magnesium results in increased expression of BGLAP protein CTD PMID:10397942 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G C3 complement C3 multiple interactions ISO [cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein; CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein] CTD PMID:11724962 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CALCA calcitonin related polypeptide alpha decreases abundance
affects metabolic processing
ISO CALCA gene mutant form results in decreased abundance of Magnesium
CALCA protein affects the metabolism of Magnesium
CTD PMID:15039145 NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,351
JBrowse link
G CASR calcium sensing receptor increases expression
multiple interactions
increases response to substance
ISO Magnesium results in increased expression of CASR mRNA; Magnesium results in increased expression of CASR protein
[Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; Magnesium binds to and results in increased activity of CASR protein
CASR protein results in increased susceptibility to Magnesium
CTD PMID:10231437 PMID:11563847 PMID:15068510 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
JBrowse link
G CCND1 cyclin D1 multiple interactions
decreases expression
ISO 1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased expression of CCND1 protein]; iodopravadoline inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased expression of CCND1 protein]]; Wortmannin inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased expression of CCND1 protein]] CTD PMID:30542433 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNE1 cyclin E1 multiple interactions
decreases expression
ISO 1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased expression of CCNE1 protein]; iodopravadoline inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased expression of CCNE1 protein]] CTD PMID:30542433 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CERK ceramide kinase multiple interactions EXP Magnesium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] CTD PMID:16269826 NCBI chr22:46,684,410...46,738,252
Ensembl chr22:46,684,410...46,738,252
JBrowse link
G CFB complement factor B multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CFD complement factor D multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein]; CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein] CTD PMID:11724962 NCBI chr19:859,664...863,641
Ensembl chr19:859,664...863,641
JBrowse link
G CLN6 CLN6 transmembrane ER protein increases abundance ISO CLN6 gene mutant form results in increased abundance of Magnesium CTD PMID:23789114 NCBI chr15:68,206,992...68,229,728
Ensembl chr15:68,206,992...68,257,211
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP [Aluminum Oxide co-treated with Magnesium] results in increased expression of COL1A1 protein CTD PMID:12209937 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL1A2 collagen type I alpha 2 chain increases expression
affects abundance
EXP
ISO
Magnesium results in increased expression of COL1A2 protein
COL1A2 protein affects the abundance of Magnesium
CTD PMID:10397942 PMID:10913914 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Magnesium co-treated with Selenium co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA CTD PMID:30031400 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G DNMT1 DNA methyltransferase 1 decreases activity
multiple interactions
EXP Magnesium results in decreased activity of DNMT1 protein
Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein]
CTD PMID:16037419 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:30031400 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO Magnesium inhibits the reaction [ifenprodil binds to and results in decreased activity of GRIN2B protein] CTD PMID:9729614 NCBI chr12:13,537,337...13,982,012
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions EXP Magnesium affects the reaction [Lithium results in decreased activity of GSK3B protein] CTD PMID:10998351 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA] CTD PMID:30031400 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions ISO Magnesium affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] CTD PMID:21126535 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
JBrowse link
G IBSP integrin binding sialoprotein increases expression EXP Magnesium results in increased expression of IBSP protein CTD PMID:10397942 NCBI chr 4:87,799,554...87,812,435
Ensembl chr 4:87,799,554...87,812,435
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO Magnesium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:13679239 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G INS insulin multiple interactions EXP [Magnesium co-treated with INS protein] results in increased phosphorylation of and results in increased activity of INSR protein; [Manganese co-treated with Magnesium co-treated with INS protein] results in increased phosphorylation of and results in increased activity of INSR protein; [Polylysine co-treated with Manganese co-treated with Magnesium] promotes the reaction [INS protein results in increased phosphorylation of and results in increased activity of INSR protein modified form]; [Polylysine co-treated with Manganese co-treated with Magnesium] promotes the reaction [INS protein results in increased phosphorylation of and results in increased activity of INSR protein] CTD PMID:2542339 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INSR insulin receptor multiple interactions EXP [Magnesium co-treated with INS protein] results in increased phosphorylation of and results in increased activity of INSR protein; [Manganese co-treated with Magnesium co-treated with INS protein] results in increased phosphorylation of and results in increased activity of INSR protein; [Polylysine co-treated with Manganese co-treated with Magnesium] promotes the reaction [INS protein results in increased phosphorylation of and results in increased activity of INSR protein modified form]; [Polylysine co-treated with Manganese co-treated with Magnesium] promotes the reaction [INS protein results in increased phosphorylation of and results in increased activity of INSR protein] CTD PMID:2542339 NCBI chr19:7,112,257...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G ITGA5 integrin subunit alpha 5 multiple interactions EXP [Aluminum Oxide co-treated with Magnesium] results in increased expression of ITGA5 protein CTD PMID:12209937 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266
JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions EXP [Aluminum Oxide co-treated with Magnesium] results in increased expression of ITGB1 protein CTD PMID:12209937 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 multiple interactions EXP Magnesium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions EXP Magnesium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
JBrowse link
G KLK1 kallikrein 1 decreases activity EXP Magnesium results in decreased activity of KLK1 protein CTD PMID:15558947 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G KLK8 kallikrein related peptidase 8 increases activity EXP Magnesium results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
JBrowse link
G LCAT lecithin-cholesterol acyltransferase multiple interactions ISO [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in decreased expression of LCAT mRNA] CTD PMID:30031400 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G MARCO macrophage receptor with collagenous structure multiple interactions EXP Magnesium promotes the reaction [titanium dioxide binds to MARCO protein] CTD PMID:18836211 NCBI chr 2:118,942,180...118,994,664
Ensembl chr 2:118,942,194...118,994,660
JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
ISO Magnesium deficiency results in decreased phosphorylation of MTOR protein
1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of MTOR protein]; iodopravadoline inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of MTOR protein]]
CTD PMID:30542433 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Magnesium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:15466955 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions ISO [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] affects the reaction [Dietary Fats results in increased expression of NR1H3 mRNA] CTD PMID:30031400 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G NT5C3A 5'-nucleotidase, cytosolic IIIA affects binding ISO Magnesium binds to NT5C3 protein CTD PMID:16672222 NCBI chr 7:33,014,113...33,062,776
Ensembl chr 7:33,014,130...33,062,796
JBrowse link
G NUDT9 nudix hydrolase 9 multiple interactions
increases activity
EXP Dithiothreitol inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Magnesium results in increased activity of NUDT9 protein]]; Fluorides inhibits the reaction [Magnesium results in increased activity of NUDT9 protein]; Hydrogen Peroxide inhibits the reaction [Magnesium results in increased activity of NUDT9 protein] CTD PMID:16860484 NCBI chr 4:87,420,002...87,459,455
Ensembl chr 4:87,422,573...87,459,455
JBrowse link
G OPRD1 opioid receptor delta 1 multiple interactions ISO Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRD1 protein]; Zinc inhibits the reaction [Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRD1 protein]] CTD PMID:2162496 NCBI chr 1:28,812,170...28,871,267
Ensembl chr 1:28,812,170...28,871,267
JBrowse link
G OPRK1 opioid receptor kappa 1 multiple interactions ISO Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRK1 protein] CTD PMID:2162496 NCBI chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637
JBrowse link
G OPRM1 opioid receptor mu 1 multiple interactions ISO Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]; Zinc inhibits the reaction [Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]] CTD PMID:2162496 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
JBrowse link
G POMC proopiomelanocortin multiple interactions
increases uptake
decreases uptake
ISO Phentolamine inhibits the reaction [POMC results in increased uptake of Magnesium]
POMC modified form results in decreased uptake of Magnesium
CTD PMID:191614 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PRKCD protein kinase C delta affects localization ISO Magnesium affects the localization of PRKCD protein CTD PMID:8106444 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PRL prolactin multiple interactions EXP Magnesium promotes the reaction [PRL protein binds to PRLR protein] CTD PMID:6197504 NCBI chr 6:22,287,246...22,302,897
Ensembl chr 6:22,287,244...22,302,826
JBrowse link
G PRLR prolactin receptor multiple interactions EXP Magnesium promotes the reaction [PRL protein binds to PRLR protein] CTD PMID:6197504 NCBI chr 5:35,048,756...35,230,724
Ensembl chr 5:35,048,756...35,230,487
JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP [Aluminum Oxide co-treated with Magnesium] results in increased expression of PTK2 protein CTD PMID:12209937 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
ISO 1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of RB1 protein]; iodopravadoline inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of RB1 protein]]; Wortmannin inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of RB1 protein]] CTD PMID:30542433 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G SERPINE1 serpin family E member 1 increases stability EXP Magnesium results in increased stability of SERPINE1 protein CTD PMID:21280127 PMID:21280128 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SHC1 SHC adaptor protein 1 multiple interactions EXP [Aluminum Oxide co-treated with Magnesium] results in increased expression of SHC1 protein; [Aluminum Oxide co-treated with Magnesium] results in increased expression of SHC1 protein alternative form CTD PMID:12209937 NCBI chr 1:154,962,298...154,974,492
Ensembl chr 1:154,962,298...154,974,395
JBrowse link
G SLC12A4 solute carrier family 12 member 4 affects expression
multiple interactions
ISO Magnesium affects the expression of SLC12A4 mRNA
Magnesium affects the reaction [SLC12A4 protein results in increased transport of Potassium]
CTD PMID:11703599 NCBI chr16:67,943,474...67,968,694
Ensembl chr16:67,943,474...67,969,601
JBrowse link
G SPARC secreted protein acidic and cysteine rich increases expression EXP Magnesium results in increased expression of SPARC protein CTD PMID:10397942 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression EXP Magnesium results in increased expression of SPP1 protein CTD PMID:10397942 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 NCBI chr17:17,811,334...17,837,017
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G THBS1 thrombospondin 1 increases expression EXP Magnesium results in increased expression of THBS1 protein CTD PMID:10397942 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Magnesium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:13679239 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions EXP Magnesium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Magnesium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 2:151,357,592...151,380,046
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO Magnesium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A mRNA] CTD PMID:13679239 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TRPM7 transient receptor potential cation channel subfamily M member 7 multiple interactions
decreases abundance
decreases activity
increases transport
affects transport
affects abundance
EXP
ISO
Magnesium inhibits the reaction [TRPM7 protein results in increased abundance of Calcium]; TRPM7 gene polymorphism affects the susceptibility to [Magnesium co-treated with Calcium, Dietary]
TRPM7 gene mutant form results in decreased abundance of Magnesium
Magnesium results in decreased activity of TRPM7 protein
TRPM7 protein results in increased transport of Magnesium
Magnesium deficiency promotes the reaction [TRPM7 protein results in increased import of Cadmium]; Magnesium inhibits the reaction [TRPM7 protein results in increased import of Cadmium]
Oxygen deficiency promotes the reaction [TRPM7 protein affects the transport of Magnesium]
TRPM7 protein affects the abundance of Magnesium
CTD PMID:17823441 PMID:19515901 PMID:20932883 PMID:21487014 PMID:30770447 NCBI chr15:50,557,158...50,686,797
Ensembl chr15:50,552,473...50,686,797
JBrowse link
G UROD uroporphyrinogen decarboxylase affects abundance EXP UROD protein affects the abundance of Magnesium CTD PMID:16325539 NCBI chr 1:45,012,254...45,015,575
Ensembl chr 1:45,010,950...45,015,575
JBrowse link
EUK-134 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of BAX protein] CTD PMID:25005833 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP EUK-134 inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein] CTD PMID:25005833 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP3 caspase 3 multiple interactions EXP EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein] CTD PMID:21647434 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 multiple interactions EXP EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP9 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein] CTD PMID:21647434 PMID:25005833 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CDC25C cell division cycle 25C multiple interactions EXP EUK-134 inhibits the reaction [diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein] CTD PMID:16707465 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP EUK-134 affects the reaction [Vitamin K 3 results in increased expression of CDKN1A protein]; EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A protein] CTD PMID:25005833 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CYGB cytoglobin multiple interactions EXP EUK-134 inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYGB mRNA] CTD PMID:25781201 NCBI chr17:76,527,356...76,557,692
Ensembl chr17:76,527,356...76,551,175
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP EUK-134 inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein]; EUK-134 inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein] CTD PMID:23885834 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [EUK-134 results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]] CTD PMID:25724285 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTA4 glutathione S-transferase alpha 4 multiple interactions ISO [Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Paraquat results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Zinc Sulfate results in increased activity of GSTA4 protein] CTD PMID:25724285 NCBI chr 6:52,977,952...52,995,332
Ensembl chr 6:52,977,948...52,995,304
JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions EXP EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of HES1 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of HES1 protein] CTD PMID:25005833 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G IAPP islet amyloid polypeptide decreases metabolic processing EXP EUK-134 results in decreased metabolism of IAPP protein CTD PMID:23528352 NCBI chr12:21,354,959...21,379,980
Ensembl chr12:21,354,959...21,379,980
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP EUK-134 inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein] CTD PMID:20962025 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP EUK-134 inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein] CTD PMID:20962025 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MDM2 MDM2 proto-oncogene multiple interactions EXP EUK-134 inhibits the reaction [Hydrogen Peroxide results in decreased expression of MDM2 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of MDM2 protein] CTD PMID:25005833 NCBI chr12:68,808,149...68,850,686
Ensembl chr12:68,808,177...68,845,544
JBrowse link
G MPO myeloperoxidase multiple interactions ISO Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 inhibits the reaction [Paraquat results in increased activity of MPO protein]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]] CTD PMID:25724285 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MT1A metallothionein 1A multiple interactions ISO Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]; EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A protein]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]] CTD PMID:25724285 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT2A metallothionein 2A multiple interactions ISO Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]; EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A protein]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]] CTD PMID:25724285 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of TP53 protein] CTD PMID:25005833 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
magnesium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC6 ATP binding cassette subfamily C member 6 multiple interactions ISO Magnesium Chloride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr16:16,149,565...16,223,617
Ensembl chr16:16,149,565...16,223,522
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 multiple interactions
decreases activity
ISO Magnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of 9-cis-retinal]; Magnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of Retinaldehyde]
Magnesium Chloride results in decreased activity of ALDH1A1 protein
CTD PMID:10998257 PMID:17167544 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression ISO Magnesium Chloride results in increased expression of BAX protein CTD PMID:17977900 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G CASP3 caspase 3 increases activity ISO Magnesium Chloride results in increased activity of CASP3 protein CTD PMID:17977900 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CD28 CD28 molecule multiple interactions EXP Magnesium Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G EGF epidermal growth factor multiple interactions EXP [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride CTD PMID:21107535 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 multiple interactions EXP Magnesium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions EXP Magnesium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
JBrowse link
G KIF5A kinesin family member 5A multiple interactions EXP Magnesium Chloride affects the reaction [zinc chloride results in decreased activity of KIF5A protein] CTD PMID:28122263 NCBI chr12:57,550,039...57,586,633
Ensembl chr12:57,546,026...57,586,633
JBrowse link
G KLK8 kallikrein related peptidase 8 increases activity EXP Magnesium Chloride results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride CTD PMID:21107535 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NUDT9 nudix hydrolase 9 multiple interactions
increases activity
EXP Dithiothreitol inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Magnesium Chloride results in increased activity of NUDT9 protein]]; Fluorides inhibits the reaction [Magnesium Chloride results in increased activity of NUDT9 protein]; Hydrogen Peroxide inhibits the reaction [Magnesium Chloride results in increased activity of NUDT9 protein] CTD PMID:16860484 NCBI chr 4:87,420,002...87,459,455
Ensembl chr 4:87,422,573...87,459,455
JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions EXP Magnesium Chloride affects the reaction [Nickel binds to SERPINE1 protein] CTD PMID:21280128 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 multiple interactions ISO [Magnesium Chloride co-treated with Phosphatidylserines] promotes the reaction [SMPD3 protein results in increased degradation of Sphingomyelins] CTD PMID:12566438 NCBI chr16:68,358,327...68,448,703
Ensembl chr16:68,358,327...68,448,508
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions EXP Magnesium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Magnesium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 2:151,357,592...151,380,046
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TP53 tumor protein p53 affects expression ISO Magnesium Chloride affects the expression of TP53 mRNA CTD PMID:10506531 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
magnesium dihydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP1 caspase 1 multiple interactions EXP
ISO
[Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased activity of CASP1 protein]; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased expression of and results in increased secretion of CASP1 protein modified form]; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 PMID:22075093 NCBI chr11:105,025,443...105,035,591
Ensembl chr11:105,025,443...105,035,250
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Magnesium Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP Magnesium Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions EXP [Aluminum Hydroxide co-treated with Magnesium Hydroxide] inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein] CTD PMID:17404311 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP
ISO
[[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein]
[[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]
CTD PMID:17404311 PMID:18604214 PMID:22075093 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1R1 interleukin 1 receptor type 1 multiple interactions ISO IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 2:102,069,638...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G IL2 interleukin 2 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]; TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]] CTD PMID:22075093 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 1:247,416,163...247,448,823
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions ISO PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]; TLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]; TLR4 protein affects the susceptibility to [Aluminum Hydroxide co-treated with Magnesium Hydroxide] CTD PMID:22075093 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
magnesium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMBS hydroxymethylbilane synthase decreases activity ISO Magnesium ion decreases activity of purified Hmbs protein RGD PMID:6732900 RGD:25394584 NCBI chr11:119,084,864...119,093,549
Ensembl chr11:119,084,866...119,093,834
JBrowse link
magnesium oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of BAX mRNA] CTD PMID:27920530 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA] CTD PMID:27920530 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA] CTD PMID:27920530 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CASP3 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP3 mRNA] CTD PMID:27920530 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 multiple interactions EXP Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA] CTD PMID:27920530 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 multiple interactions EXP Magnesium Oxide analog inhibits the reaction [Diazinon results in increased activity of CASP9 protein]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]; Selenium analog inhibits the reaction [Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]] CTD PMID:27920530 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases expression ISO Magnesium Oxide results in decreased expression of CAT protein CTD PMID:29282847 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CFLAR mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CFLAR mRNA] CTD PMID:27920530 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CYCS mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CYCS mRNA] CTD PMID:27920530 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G FADD Fas associated via death domain multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FADD mRNA]; Magnesium Oxide promotes the reaction [Diazinon results in decreased expression of FADD mRNA] CTD PMID:27920530 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
JBrowse link
G FAS Fas cell surface death receptor multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of FAS mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of FAS mRNA] CTD PMID:27920530 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASLG Fas ligand multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA] CTD PMID:27920530 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G INS insulin multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased secretion of INS protein alternative form]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased secretion of INS protein]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased secretion of INS protein alternative form]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased secretion of INS protein] CTD PMID:27920530 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a multiple interactions EXP Magnesium Oxide analog promotes the reaction [Diazinon results in decreased expression of TNFRSF10A mRNA] CTD PMID:27920530 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TNFRSF1A mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TNFRSF1A mRNA] CTD PMID:27920530 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TP53 mRNA] CTD PMID:27920530 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRAF2 TNF receptor associated factor 2 multiple interactions EXP Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TRAF2 mRNA] CTD PMID:27920530 NCBI chr 9:136,881,933...136,926,615
Ensembl chr 9:136,881,912...136,926,607
JBrowse link
magnesium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCHE butyrylcholinesterase multiple interactions ISO Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein] CTD PMID:19504058 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G CAT catalase multiple interactions ISO Magnesium Sulfate promotes the reaction [Vanadates results in decreased activity of CAT protein] CTD PMID:29453945 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression
EXP Magnesium Sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]
Magnesium Sulfate results in increased expression of CXCL8 mRNA
CTD PMID:16384605 PMID:29594315 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases activity
ISO [Magnesium Sulfate co-treated with Vanadates] results in decreased activity of GSR protein
Magnesium Sulfate results in decreased activity of GSR protein
CTD PMID:29453945 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G IL1B interleukin 1 beta decreases expression EXP Magnesium Sulfate results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 decreases expression ISO Magnesium Sulfate results in decreased expression of KCNC2 mRNA; Magnesium Sulfate results in decreased expression of KCNC2 protein CTD PMID:18775767 NCBI chr12:75,040,078...75,209,839
Ensembl chr12:75,040,077...75,209,839
JBrowse link
G KLK8 kallikrein related peptidase 8 increases activity EXP Magnesium Sulfate results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
JBrowse link
G REN renin increases activity EXP Magnesium Sulfate results in increased activity of REN protein CTD PMID:1874207 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G TRPM5 transient receptor potential cation channel subfamily M member 5 affects response to substance ISO TRPM5 protein affects the susceptibility to Magnesium Sulfate CTD PMID:19244541 NCBI chr11:2,403,962...2,444,514
Ensembl chr11:2,404,515...2,423,045
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25196
    chemical entity 25168
      atom 25159
        metal atom 19895
          alkaline earth metal atom 710
            magnesium atom 116
              magnesium molecular entity + 62
              magnesium-25 atom 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 25196
    subatomic particle 25159
      composite particle 25159
        hadron 25159
          baryon 25159
            nucleon 25159
              atomic nucleus 25159
                atom 25159
                  metal atom 19895
                    alkaline earth metal atom 710
                      magnesium atom 116
                        magnesium molecular entity + 62
                        magnesium-25 atom 0
paths to the root