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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:macrolide antibiotic
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Accession:CHEBI:25105 term browser browse the term
Definition:A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity.
Synonyms:related_synonym: Makrolidantibiotika;   macrolide antibiotics


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(E)-roxithromycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator decreases expression EXP Roxithromycin results in decreased expression of BCL2 protein CTD PMID:12921874 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of CXCL8 mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of CXCL8 protein] CTD PMID:17524151 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 decreases activity EXP Roxithromycin results in decreased activity of CYP2B6 protein CTD PMID:17164692 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
decreases activity
decreases expression		 EXP Roxithromycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]
Roxithromycin results in decreased activity of CYP3A4 protein
Roxithromycin results in decreased expression of CYP3A4 mRNA		 CTD PMID:16416302 PMID:16837568 PMID:17164692 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G FASLG Fas ligand increases expression EXP Roxithromycin results in increased expression of FASLG protein CTD PMID:12921874 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Roxithromycin results in increased expression of FOS mRNA; Roxithromycin results in increased expression of FOS protein CTD PMID:32454074 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP
ISO		 Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL1B mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL1B protein]
Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]		 CTD PMID:17524151 PMID:18197913 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL6 mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL6 protein] CTD PMID:17524151 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGB4 integrin subunit beta 4 decreases expression EXP Roxithromycin results in decreased expression of ITGB4 protein CTD PMID:14687228 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818 		JBrowse link
G LAMC2 laminin subunit gamma 2 decreases expression EXP Roxithromycin results in decreased expression of LAMC2 protein CTD PMID:14687228 NCBI chr 1:183,186,264...183,258,968
Ensembl chr 1:183,186,238...183,245,127 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC protein] CTD PMID:18197913 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:16061884 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP
ISO		 Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of NOS2 protein]
Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of NOS2 protein]		 CTD PMID:16061884 PMID:17524151 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:16061884 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of TNF mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of TNF protein]
Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]		 CTD PMID:17524151 PMID:18197913 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
abamectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 decreases expression
increases expression
multiple interactions
decreases activity
decreases response to substance		 ISO
EXP		 abamectin results in decreased expression of ABCB1A protein
abamectin results in increased expression of ABCB1A mRNA
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Sesame Oil inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]
abamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
abamectin results in decreased activity of ABCB1 protein
abamectin results in decreased activity of ABCB1A protein
abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
ABCB1A protein results in decreased susceptibility to abamectin		 CTD PMID:9144452 PMID:17134887 PMID:19879343 PMID:25865432 PMID:31739238 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) multiple interactions
decreases activity		 EXP
ISO		 abamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
abamectin results in decreased activity of ABCC1 protein		 CTD PMID:25865432 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ACTB actin beta decreases expression ISO abamectin results in decreased expression of ACTB protein CTD PMID:19879343 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression EXP abamectin results in decreased expression of AKT1 protein CTD PMID:30958899 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ANO1 anoctamin 1 decreases activity ISO abamectin results in decreased activity of ANO1 protein CTD PMID:32201246 NCBI chr11:69,965,997...70,189,530
Ensembl chr11:69,985,907...70,189,530 		JBrowse link
G ATF6 activating transcription factor 6 increases expression
multiple interactions		 ISO abamectin results in increased expression of ATF6 mRNA
Hesperidin inhibits the reaction [abamectin results in increased expression of ATF6 mRNA]		 CTD PMID:34748272 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of BAX mRNA]; Hesperidin inhibits the reaction [abamectin results in increased expression of BAX protein]
abamectin results in increased expression of BAX mRNA; abamectin results in increased expression of BAX protein		 CTD PMID:34748272 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 ISO Hesperidin inhibits the reaction [abamectin results in decreased expression of BCL2 mRNA]; Hesperidin inhibits the reaction [abamectin results in decreased expression of BCL2 protein]
abamectin results in decreased expression of BCL2 mRNA; abamectin results in decreased expression of BCL2 protein		 CTD PMID:34748272 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BECN1 beclin 1 multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of BECN1 protein] CTD PMID:34748272 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CASP3 caspase 3 increases activity
increases expression
multiple interactions		 EXP
ISO		 abamectin results in increased activity of CASP3 protein
abamectin results in increased expression of CASP3 mRNA; abamectin results in increased expression of CASP3 protein
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Hesperidin inhibits the reaction [abamectin results in increased expression of CASP3 mRNA]; Hesperidin inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Sesame Oil inhibits the reaction [abamectin results in increased expression of CASP3 protein]		 CTD PMID:30958899 PMID:31739238 PMID:34748272 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase increases activity
decreases activity
multiple interactions		 ISO abamectin results in increased activity of CAT protein
abamectin results in decreased activity of CAT protein
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased activity of CAT protein]; Hesperidin inhibits the reaction [abamectin results in decreased activity of CAT protein]; Sesame Oil inhibits the reaction [abamectin results in increased activity of CAT protein]		 CTD PMID:31739238 PMID:34748272 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases expression
multiple interactions		 ISO abamectin results in increased expression of CYP2E1 protein
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Sesame Oil inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]		 CTD PMID:31739238 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 ISO abamectin results in increased expression of EIF2AK3 mRNA
Hesperidin inhibits the reaction [abamectin results in increased expression of EIF2AK3 mRNA]		 CTD PMID:34748272 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions		 ISO abamectin results in increased expression of ERN1 mRNA
Hesperidin inhibits the reaction [abamectin results in increased expression of ERN1 mRNA]		 CTD PMID:34748272 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
decreases expression		 ISO Hesperidin inhibits the reaction [abamectin results in decreased expression of HMOX1 mRNA] CTD PMID:34748272 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of HSPA5 mRNA] CTD PMID:34748272 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions		 ISO abamectin results in increased expression of IL1B mRNA
Hesperidin inhibits the reaction [abamectin results in increased expression of IL1B mRNA]		 CTD PMID:34748272 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of IL6 mRNA] CTD PMID:34748272 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of JAK2 mRNA] CTD PMID:34748272 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of MAP1LC3A mRNA] CTD PMID:34748272 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of MAP1LC3B mRNA] CTD PMID:34748272 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 increases expression
multiple interactions		 ISO abamectin results in increased expression of MAPK14 mRNA
Hesperidin inhibits the reaction [abamectin results in increased expression of MAPK14 mRNA]		 CTD PMID:34748272 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions		 ISO abamectin results in decreased expression of NFE2L2 mRNA
Hesperidin inhibits the reaction [abamectin results in decreased expression of NFE2L2 mRNA]		 CTD PMID:34748272 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of NFKB1 mRNA] CTD PMID:34748272 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions EXP abamectin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; abamectin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G SQSTM1 sequestosome 1 decreases expression EXP abamectin results in decreased expression of SQSTM1 protein CTD PMID:30958899 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions
increases expression		 ISO Hesperidin inhibits the reaction [abamectin results in increased expression of STAT3 mRNA] CTD PMID:34748272 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions		 ISO abamectin results in increased expression of TNF mRNA; abamectin results in increased expression of TNF protein
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of TNF protein]; Hesperidin inhibits the reaction [abamectin results in increased expression of TNF mRNA]; Sesame Oil inhibits the reaction [abamectin results in increased expression of TNF protein]		 CTD PMID:31739238 PMID:34748272 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TUBB3 tubulin beta 3 class III decreases expression ISO abamectin results in decreased expression of TUBB3 protein CTD PMID:19879343 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
amphotericin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCA1 mRNA CTD PMID:36464106 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCA12 ATP binding cassette subfamily A member 12 decreases expression EXP Amphotericin B analog results in decreased expression of ABCA12 mRNA CTD PMID:28534445 NCBI chr 2:214,931,542...215,138,626
Ensembl chr 2:214,931,542...215,138,626 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB1A mRNA CTD PMID:36464106 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB11 mRNA CTD PMID:36464106 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA CTD PMID:36464106 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNA CTD PMID:36464106 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 decreases expression EXP Amphotericin B analog results in decreased expression of ABCG1 mRNA CTD PMID:28534445 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA CTD PMID:36464106 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA CTD PMID:36464106 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865 		JBrowse link
G ACRV1 acrosomal vesicle protein 1 increases expression EXP Amphotericin B analog results in increased expression of ACRV1 mRNA CTD PMID:28534445 NCBI chr11:125,671,522...125,680,847
Ensembl chr11:125,671,522...125,680,874 		JBrowse link
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 increases expression EXP Amphotericin B analog results in increased expression of ADAMTS12 mRNA CTD PMID:28534445 NCBI chr 5:33,523,535...33,891,990
Ensembl chr 5:33,523,535...33,892,019 		JBrowse link
G ADCY2 adenylate cyclase 2 increases expression EXP Amphotericin B analog results in increased expression of ADCY2 mRNA CTD PMID:28534445 NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081 		JBrowse link
G ADORA3 adenosine A3 receptor increases expression EXP Amphotericin B analog results in increased expression of ADORA3 mRNA CTD PMID:28534445 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633 		JBrowse link
G ADRA2A adrenoceptor alpha 2A decreases expression EXP Amphotericin B analog results in decreased expression of ADRA2A mRNA CTD PMID:28534445 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G ALDH8A1 aldehyde dehydrogenase 8 family member A1 decreases expression EXP Amphotericin B analog results in decreased expression of ALDH8A1 mRNA CTD PMID:28534445 NCBI chr 6:134,917,393...134,950,101
Ensembl chr 6:134,917,393...134,950,115 		JBrowse link
G ALK ALK receptor tyrosine kinase increases expression EXP Amphotericin B results in increased expression of ALK mRNA CTD PMID:28534445 NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase decreases expression EXP Amphotericin B analog results in decreased expression of ALOX5 mRNA CTD PMID:28534445 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G AMACR alpha-methylacyl-CoA racemase decreases expression EXP Amphotericin B analog results in decreased expression of AMACR mRNA CTD PMID:28534445 NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104 		JBrowse link
G ANK3 ankyrin 3 decreases expression EXP Amphotericin B analog results in decreased expression of ANK3 mRNA CTD PMID:28534445 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490 		JBrowse link
G ANXA9 annexin A9 decreases expression EXP Amphotericin B analog results in decreased expression of ANXA9 mRNA CTD PMID:28534445 NCBI chr 1:150,977,306...150,995,634
Ensembl chr 1:150,982,249...150,995,634 		JBrowse link
G AP3B2 adaptor related protein complex 3 subunit beta 2 increases expression EXP Amphotericin B analog results in increased expression of AP3B2 mRNA CTD PMID:28534445 NCBI chr15:82,659,281...82,709,875
Ensembl chr15:82,659,281...82,710,112 		JBrowse link
G APBB2 amyloid beta precursor protein binding family B member 2 increases expression EXP Amphotericin B analog results in increased expression of APBB2 mRNA CTD PMID:28534445 NCBI chr 4:40,810,027...41,214,542
Ensembl chr 4:40,810,027...41,216,714 		JBrowse link
G APOC2 apolipoprotein C2 increases expression EXP Amphotericin B analog results in increased expression of APOC2 mRNA CTD PMID:28534445 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) decreases expression EXP Amphotericin B analog results in decreased expression of AQP3 mRNA CTD PMID:28534445 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
G AQP5 aquaporin 5 increases expression EXP Amphotericin B analog results in increased expression of AQP5 mRNA CTD PMID:28534445 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682 		JBrowse link
G ARG2 arginase 2 decreases expression EXP Amphotericin B analog results in decreased expression of ARG2 mRNA CTD PMID:28534445 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ARHGEF26 Rho guanine nucleotide exchange factor 26 increases expression EXP Amphotericin B results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 3:154,121,003...154,257,825
Ensembl chr 3:154,121,003...154,257,827 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator multiple interactions EXP Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer] CTD PMID:16189267 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ARRB1 arrestin beta 1 increases expression EXP Amphotericin B analog results in increased expression of ARRB1 mRNA CTD PMID:28534445 NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705 		JBrowse link
G ATG3 autophagy related 3 decreases expression EXP Amphotericin B results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046 		JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) increases expression EXP Amphotericin B analog results in increased expression of ATP10B mRNA CTD PMID:28534445 NCBI chr 5:160,563,120...160,929,360
Ensembl chr 5:160,563,120...160,852,214 		JBrowse link
G B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 increases expression EXP Amphotericin B analog results in increased expression of B3GNT4 mRNA CTD PMID:28534445 NCBI chr12:122,203,709...122,208,952
Ensembl chr12:122,203,681...122,208,952 		JBrowse link
G BAG4 BAG cochaperone 4 decreases expression EXP Amphotericin B analog results in decreased expression of BAG4 mRNA CTD PMID:28534445 NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301 		JBrowse link
G BCL6 BCL6 transcription repressor decreases expression EXP Amphotericin B analog results in decreased expression of BCL6 mRNA CTD PMID:28534445 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
G BEND5 BEN domain containing 5 decreases expression EXP Amphotericin B analog results in decreased expression of BEND5 mRNA CTD PMID:28534445 NCBI chr 1:48,727,519...48,776,891
Ensembl chr 1:48,727,519...48,776,969 		JBrowse link
G BMP2 bone morphogenetic protein 2 decreases expression EXP Amphotericin B analog results in decreased expression of BMP2 mRNA; Amphotericin B results in decreased expression of BMP2 mRNA CTD PMID:28534445 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP7 bone morphogenetic protein 7 increases expression EXP Amphotericin B analog results in increased expression of BMP7 mRNA CTD PMID:28534445 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G BNC1 basonuclin zinc finger protein 1 increases expression EXP Amphotericin B analog results in increased expression of BNC1 mRNA CTD PMID:28534445 NCBI chr15:83,255,884...83,284,664
Ensembl chr15:83,255,884...83,284,664 		JBrowse link
G BORA BORA aurora kinase A activator decreases expression EXP Amphotericin B analog results in decreased expression of BORA mRNA CTD PMID:28534445 NCBI chr13:72,727,923...72,756,196
Ensembl chr13:72,727,749...72,756,198 		JBrowse link
G CA12 carbonic anhydrase 12 decreases expression EXP Amphotericin B analog results in decreased expression of CA12 mRNA CTD PMID:28534445 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846 		JBrowse link
G CA14 carbonic anhydrase 14 increases expression EXP Amphotericin B analog results in increased expression of CA14 mRNA CTD PMID:28534445 NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078 		JBrowse link
G CA4 carbonic anhydrase 4 decreases expression EXP Amphotericin B analog results in decreased expression of CA4 mRNA CTD PMID:28534445 NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899 		JBrowse link
G CA9 carbonic anhydrase 9 decreases expression EXP Amphotericin B analog results in decreased expression of CA9 mRNA CTD PMID:28534445 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159 		JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma increases expression EXP Amphotericin B analog results in increased expression of CAMK2G mRNA CTD PMID:28534445 NCBI chr10:73,812,501...73,874,555
Ensembl chr10:73,812,501...73,874,591 		JBrowse link
G CAPN6 calpain 6 decreases expression EXP Amphotericin B analog results in decreased expression of CAPN6 mRNA CTD PMID:28534445 NCBI chr  X:111,245,099...111,270,483
Ensembl chr  X:111,245,099...111,270,483 		JBrowse link
G CARF calcium responsive transcription factor decreases expression EXP Amphotericin B analog results in decreased expression of CARF mRNA CTD PMID:28534445 NCBI chr 2:202,912,275...202,988,263
Ensembl chr 2:202,912,214...202,988,263 		JBrowse link
G CASP3 caspase 3 increases expression ISO Amphotericin B results in increased expression of CASP3 protein CTD PMID:23988732 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASQ2 calsequestrin 2 increases expression EXP Amphotericin B analog results in increased expression of CASQ2 mRNA CTD PMID:28534445 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,884 		JBrowse link
G CAT catalase decreases expression ISO Amphotericin B results in decreased expression of CAT mRNA CTD PMID:20623750 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 increases expression EXP Amphotericin B analog results in increased expression of CCL20 mRNA; Amphotericin B results in increased expression of CCL20 mRNA CTD PMID:28534445 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCNE2 cyclin E2 decreases expression EXP Amphotericin B results in decreased expression of CCNE2 mRNA CTD PMID:28534445 NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 decreases expression ISO Amphotericin B results in decreased expression of CCR2 mRNA CTD PMID:20623750 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CD14 CD14 molecule decreases expression EXP Amphotericin B analog results in decreased expression of CD14 mRNA CTD PMID:28534445 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD1C CD1c molecule increases expression EXP Amphotericin B analog results in increased expression of CD1C mRNA CTD PMID:28534445 NCBI chr 1:158,289,923...158,294,774
Ensembl chr 1:158,289,923...158,294,774 		JBrowse link
G CD1D CD1d molecule decreases expression EXP Amphotericin B analog results in decreased expression of CD1D mRNA CTD PMID:28534445 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CD2 CD2 molecule increases expression EXP Amphotericin B analog results in increased expression of CD2 mRNA CTD PMID:28534445 NCBI chr 1:116,754,430...116,769,229
Ensembl chr 1:116,754,430...116,769,229 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex increases expression EXP Amphotericin B analog results in increased expression of CD3E mRNA CTD PMID:28534445 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD84 CD84 molecule increases expression EXP Amphotericin B analog results in increased expression of CD84 mRNA CTD PMID:28534445 NCBI chr 1:160,541,098...160,579,496
Ensembl chr 1:160,541,095...160,579,516 		JBrowse link
G CDKL5 cyclin dependent kinase like 5 increases expression EXP Amphotericin B analog results in increased expression of CDKL5 mRNA CTD PMID:28534445 NCBI chr  X:18,425,608...18,653,629
Ensembl chr  X:18,425,583...18,653,629 		JBrowse link
G CDSN corneodesmosin increases expression EXP Amphotericin B analog results in increased expression of CDSN mRNA CTD PMID:28534445 NCBI chr 6:31,115,087...31,120,446
Ensembl chr 6:31,115,087...31,120,446 		JBrowse link
G CEACAM21 CEA cell adhesion molecule 21 increases expression EXP Amphotericin B analog results in increased expression of CEACAM21 mRNA CTD PMID:28534445 NCBI chr19:41,549,518...41,586,844
Ensembl chr19:41,549,518...41,586,844 		JBrowse link
G CEP76 centrosomal protein 76 decreases expression EXP Amphotericin B analog results in decreased expression of CEP76 mRNA CTD PMID:28534445 NCBI chr18:12,661,956...12,702,777
Ensembl chr18:12,661,833...12,702,777 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide increases expression EXP Amphotericin B analog results in increased expression of CGA mRNA CTD PMID:28534445 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 increases expression EXP Amphotericin B analog results in increased expression of CHAC1 mRNA CTD PMID:28534445 NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512 		JBrowse link
G CHI3L1 chitinase 3 like 1 decreases expression EXP Amphotericin B analog results in decreased expression of CHI3L1 mRNA CTD PMID:28534445 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHL1 cell adhesion molecule L1 like decreases expression EXP Amphotericin B analog results in decreased expression of CHL1 mRNA CTD PMID:28534445 NCBI chr 3:196,763...409,417
Ensembl chr 3:196,763...409,417 		JBrowse link
G CHP1 calcineurin like EF-hand protein 1 decreases expression EXP Amphotericin B analog results in decreased expression of CHP1 mRNA CTD PMID:28534445 NCBI chr15:41,231,268...41,281,887
Ensembl chr15:41,230,839...41,281,887 		JBrowse link
G CHRNB3 cholinergic receptor nicotinic beta 3 subunit increases expression EXP Amphotericin B analog results in increased expression of CHRNB3 mRNA CTD PMID:28534445 NCBI chr 8:42,697,366...42,737,407
Ensembl chr 8:42,697,366...42,737,407 		JBrowse link
G CLU clusterin affects expression
decreases expression		 ISO
EXP		 Amphotericin B affects the expression of CLU mRNA
Amphotericin B analog results in decreased expression of CLU mRNA		 CTD PMID:20623750 PMID:28534445 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene decreases expression EXP Amphotericin B analog results in decreased expression of CMAHP mRNA CTD PMID:28534445 NCBI chr 6:25,081,067...25,138,392
Ensembl chr 6:25,081,862...25,138,081 		JBrowse link
G CNR2 cannabinoid receptor 2 increases expression EXP Amphotericin B analog results in increased expression of CNR2 mRNA CTD PMID:28534445 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362 		JBrowse link
G CNTN5 contactin 5 increases expression EXP Amphotericin B analog results in increased expression of CNTN5 mRNA CTD PMID:28534445 NCBI chr11:99,020,949...100,358,885
Ensembl chr11:99,020,949...100,358,885 		JBrowse link
G COL5A1 collagen type V alpha 1 chain increases expression EXP Amphotericin B analog results in increased expression of COL5A1 mRNA CTD PMID:28534445 NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843 		JBrowse link
G COMT catechol-O-methyltransferase increases expression EXP Amphotericin B analog results in increased expression of COMT mRNA CTD PMID:28534445 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CPD carboxypeptidase D decreases expression EXP Amphotericin B analog results in decreased expression of CPD mRNA CTD PMID:28534445 NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989 		JBrowse link
G CPT1B carnitine palmitoyltransferase 1B decreases expression EXP Amphotericin B analog results in decreased expression of CPT1B mRNA CTD PMID:28534445 NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465 		JBrowse link
G CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 increases expression EXP Amphotericin B analog results in increased expression of CRISPLD2 mRNA CTD PMID:28534445 NCBI chr16:84,819,985...84,909,508
Ensembl chr16:84,819,985...84,920,768 		JBrowse link
G CRYBB1 crystallin beta B1 increases expression EXP Amphotericin B analog results in increased expression of CRYBB1 mRNA CTD PMID:28534445 NCBI chr22:26,599,278...26,618,027
Ensembl chr22:26,599,278...26,618,027 		JBrowse link
G CSF2 colony stimulating factor 2 increases expression EXP Amphotericin B analog results in increased expression of CSF2 mRNA; Amphotericin B results in increased expression of CSF2 mRNA CTD PMID:28534445 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 increases expression EXP Amphotericin B analog results in increased expression of CSGALNACT2 mRNA CTD PMID:28534445 NCBI chr10:43,138,445...43,185,308
Ensembl chr10:43,138,445...43,185,302 		JBrowse link
G CSPG5 chondroitin sulfate proteoglycan 5 decreases expression EXP Amphotericin B analog results in decreased expression of CSPG5 mRNA CTD PMID:28534445 NCBI chr 3:47,562,238...47,580,240
Ensembl chr 3:47,562,238...47,580,792 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression EXP Amphotericin B analog results in increased expression of CXCL1 mRNA CTD PMID:28534445 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 increases expression EXP Amphotericin B analog results in increased expression of CXCL2 mRNA; Amphotericin B results in increased expression of CXCL2 mRNA CTD PMID:28534445 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 increases expression EXP Amphotericin B results in increased expression of CXCL5 mRNA CTD PMID:28534445 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions		 EXP Amphotericin B analog results in increased expression of CXCL8 mRNA; Amphotericin B results in increased expression of CXCL8 mRNA
[Amphotericin B co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA		 CTD PMID:28534445 PMID:29594315 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 decreases expression EXP Amphotericin B analog results in decreased expression of CXCR4 mRNA CTD PMID:28534445 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA CTD PMID:36464106 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 increases expression EXP Amphotericin B analog results in increased expression of CYP2C19 mRNA CTD PMID:28534445 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 increases expression EXP Amphotericin B analog results in increased expression of CYP4A11 mRNA CTD PMID:28534445 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484 		JBrowse link
G CYP4B1 cytochrome P450 family 4 subfamily B member 1 decreases expression EXP Amphotericin B analog results in decreased expression of CYP4B1 mRNA CTD PMID:28534445 NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA CTD PMID:36464106 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7B1 mRNA CTD PMID:36464106 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA CTD PMID:36464106 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G CYTH4 cytohesin 4 increases expression EXP Amphotericin B analog results in increased expression of CYTH4 mRNA CTD PMID:28534445 NCBI chr22:37,282,508...37,315,341
Ensembl chr22:37,282,027...37,315,341 		JBrowse link
G DCLK1 doublecortin like kinase 1 decreases expression EXP Amphotericin B analog results in decreased expression of DCLK1 mRNA CTD PMID:28534445 NCBI chr13:35,768,652...36,131,939
Ensembl chr13:35,768,652...36,131,382 		JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein increases expression EXP Amphotericin B analog results in increased expression of DCSTAMP mRNA CTD PMID:28534445 NCBI chr 8:104,339,796...104,356,689
Ensembl chr 8:104,339,087...104,356,689 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Amphotericin B results in increased expression of DDIT3 mRNA CTD PMID:28534445 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDR1-DT DDR1 divergent transcript increases expression EXP Amphotericin B analog results in increased expression of DDR1-DT mRNA CTD PMID:28534445 Ensembl chr 6:30,866,982...30,875,918 JBrowse link
G DDX11 DEAD/H-box helicase 11 increases expression EXP Amphotericin B results in increased expression of DDX11 mRNA CTD PMID:28534445 NCBI chr12:31,073,860...31,104,799
Ensembl chr12:31,073,860...31,104,799 		JBrowse link
G DDX12P DEAD/H-box helicase 12, pseudogene increases expression EXP Amphotericin B results in increased expression of DDX12P mRNA CTD PMID:28534445 NCBI chr12:9,417,691...9,448,172
Ensembl chr12:9,418,673...9,448,229 		JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein decreases expression EXP Amphotericin B analog results in decreased expression of DEPTOR mRNA CTD PMID:28534445 NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 decreases expression EXP Amphotericin B analog results in decreased expression of DHRS7 mRNA CTD PMID:28534445 NCBI chr14:60,144,119...60,169,889
Ensembl chr14:60,144,119...60,169,856 		JBrowse link
G DICER1 dicer 1, ribonuclease III decreases expression EXP Amphotericin B analog results in decreased expression of DICER1 mRNA CTD PMID:28534445 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DKK4 dickkopf WNT signaling pathway inhibitor 4 increases expression EXP Amphotericin B analog results in increased expression of DKK4 mRNA CTD PMID:28534445 NCBI chr 8:42,374,063...42,391,322
Ensembl chr 8:42,374,063...42,377,229 		JBrowse link
G DLGAP1 DLG associated protein 1 decreases expression
increases expression		 EXP Amphotericin B analog results in decreased expression of DLGAP1 mRNA
Amphotericin B analog results in increased expression of DLGAP1 mRNA		 CTD PMID:28534445 NCBI chr18:3,496,032...4,455,307
Ensembl chr18:3,496,032...4,455,307 		JBrowse link
G DNAH3 dynein axonemal heavy chain 3 increases expression EXP Amphotericin B analog results in increased expression of DNAH3 mRNA CTD PMID:28534445 NCBI chr16:20,933,111...21,159,459
Ensembl chr16:20,933,111...21,159,441 		JBrowse link
G DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 increases expression EXP Amphotericin B analog results in increased expression of DNAJA4 mRNA CTD PMID:28534445 NCBI chr15:78,264,145...78,282,191
Ensembl chr15:78,264,086...78,282,196 		JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 decreases expression EXP Amphotericin B analog results in decreased expression of DTX4 mRNA CTD PMID:28534445 NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588 		JBrowse link
G DUOX2 dual oxidase 2 increases expression EXP Amphotericin B analog results in increased expression of DUOX2 mRNA CTD PMID:28534445 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
G DZIP3 DAZ interacting zinc finger protein 3 decreases expression EXP Amphotericin B analog results in decreased expression of DZIP3 mRNA CTD PMID:28534445 NCBI chr 3:108,589,510...108,694,840
Ensembl chr 3:108,589,705...108,694,840 		JBrowse link
G E2F2 E2F transcription factor 2 increases expression EXP Amphotericin B analog results in increased expression of E2F2 mRNA CTD PMID:28534445 NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233 		JBrowse link
G EDNRB endothelin receptor type B increases expression EXP Amphotericin B results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EFR3B EFR3 homolog B increases expression EXP Amphotericin B analog results in increased expression of EFR3B mRNA CTD PMID:28534445 NCBI chr 2:25,042,076...25,159,135
Ensembl chr 2:25,042,076...25,159,135 		JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 decreases expression EXP Amphotericin B analog results in decreased expression of EGLN3 mRNA CTD PMID:28534445 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774 		JBrowse link
G EMX2 empty spiracles homeobox 2 decreases expression EXP Amphotericin B analog results in decreased expression of EMX2 mRNA CTD PMID:28534445 NCBI chr10:117,542,746...117,549,546
Ensembl chr10:117,542,445...117,549,546 		JBrowse link
G ENO1 enolase 1 multiple interactions EXP Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of ENO1 mRNA]; Amphotericin B results in increased expression of and results in increased secretion of ENO1 protein CTD PMID:16189267 PMID:26259607 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP Amphotericin B analog results in decreased expression of ENPP2 mRNA CTD PMID:28534445 NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453 		JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:16189267 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G EPO erythropoietin multiple interactions
decreases expression		 EXP
ISO		 Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]
Amphotericin B results in decreased expression of EPO protein		 CTD PMID:697352 PMID:2299214 PMID:16189267 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G EPOR erythropoietin receptor increases expression EXP Amphotericin B analog results in increased expression of EPOR mRNA; Amphotericin B results in increased expression of EPOR mRNA CTD PMID:28534445 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G EREG epiregulin increases expression EXP Amphotericin B analog results in increased expression of EREG mRNA CTD PMID:28534445 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G FAM13A family with sequence similarity 13 member A decreases expression EXP Amphotericin B analog results in decreased expression of FAM13A mRNA CTD PMID:28534445 NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398 		JBrowse link
G FAM200C family with sequence similarity 200 member C decreases expression EXP Amphotericin B analog results in decreased expression of ZBED8 mRNA CTD PMID:28534445 NCBI chr 5:160,393,148...160,400,054
Ensembl chr 5:160,393,148...160,400,054 		JBrowse link
G FASN fatty acid synthase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA CTD PMID:36464106 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FBLN1 fibulin 1 increases expression EXP Amphotericin B analog results in increased expression of FBLN1 mRNA CTD PMID:28534445 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135 		JBrowse link
G FCGR1A Fc gamma receptor Ia increases expression EXP Amphotericin B analog results in increased expression of FCGR1A mRNA CTD PMID:28534445 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675 		JBrowse link
G FCGR1CP Fc gamma receptor Ic, pseudogene increases expression EXP Amphotericin B analog results in increased expression of FCGR1CP mRNA CTD PMID:28534445 NCBI chr 1:143,874,743...143,883,733
Ensembl chr 1:143,874,793...143,883,575 		JBrowse link
G FGB fibrinogen beta chain decreases expression EXP Amphotericin B analog results in decreased expression of FGB mRNA CTD PMID:28534445 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FGF4 fibroblast growth factor 4 increases expression EXP Amphotericin B analog results in increased expression of FGF4 mRNA CTD PMID:28534445 NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 decreases expression EXP Amphotericin B analog results in decreased expression of FKBP5 mRNA CTD PMID:28534445 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FLRT3 fibronectin leucine rich transmembrane protein 3 decreases expression EXP Amphotericin B analog results in decreased expression of FLRT3 mRNA; Amphotericin B results in decreased expression of FLRT3 mRNA CTD PMID:28534445 NCBI chr20:14,322,985...14,337,612
Ensembl chr20:14,322,985...14,337,614 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Amphotericin B analog results in increased expression of FOSB mRNA CTD PMID:28534445 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FRMD4B FERM domain containing 4B decreases expression EXP Amphotericin B analog results in decreased expression of FRMD4B mRNA CTD PMID:28534445 NCBI chr 3:69,168,782...69,542,586
Ensembl chr 3:69,168,782...69,542,583 		JBrowse link
G FSBP fibrinogen silencer binding protein decreases expression EXP Amphotericin B analog results in decreased expression of FSBP mRNA CTD PMID:28534445 NCBI chr 8:94,427,716...94,436,944
Ensembl chr 8:94,378,377...94,436,952 		JBrowse link
G FUBP1 far upstream element binding protein 1 decreases expression EXP Amphotericin B analog results in decreased expression of FUBP1 mRNA CTD PMID:28534445 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G FXR1 FMR1 autosomal homolog 1 decreases expression EXP Amphotericin B analog results in decreased expression of FXR1 mRNA CTD PMID:28534445 NCBI chr 3:180,912,670...180,982,753
Ensembl chr 3:180,868,141...180,982,753 		JBrowse link
G FXYD3 FXYD domain containing ion transport regulator 3 increases expression EXP Amphotericin B analog results in increased expression of FXYD3 mRNA CTD PMID:28534445 NCBI chr19:35,115,823...35,124,324
Ensembl chr19:35,115,823...35,124,324 		JBrowse link
G GAL3ST1 galactose-3-O-sulfotransferase 1 decreases expression EXP Amphotericin B analog results in decreased expression of GAL3ST1 mRNA CTD PMID:28534445 NCBI chr22:30,554,635...30,574,665
Ensembl chr22:30,554,635...30,574,665 		JBrowse link
G GALR3 galanin receptor 3 increases expression EXP Amphotericin B analog results in increased expression of GALR3 mRNA CTD PMID:28534445 NCBI chr22:37,823,382...37,825,485
Ensembl chr22:37,823,382...37,825,485 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP Amphotericin B analog results in increased expression of GDF15 mRNA; Amphotericin B results in increased expression of GDF15 mRNA CTD PMID:28534445 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GFRA3 GDNF family receptor alpha 3 increases expression EXP Amphotericin B analog results in increased expression of GFRA3 mRNA CTD PMID:28534445 NCBI chr 5:138,252,380...138,274,621
Ensembl chr 5:138,252,380...138,274,621 		JBrowse link
G GFRA4 GDNF family receptor alpha 4 increases expression EXP Amphotericin B analog results in increased expression of GFRA4 mRNA CTD PMID:28534445 NCBI chr20:3,659,248...3,663,399
Ensembl chr20:3,659,248...3,663,399 		JBrowse link
G GLCE glucuronic acid epimerase decreases expression EXP Amphotericin B analog results in decreased expression of GLCE mRNA CTD PMID:28534445 NCBI chr15:69,160,635...69,272,207
Ensembl chr15:69,160,584...69,272,217 		JBrowse link
G GLOD4 glyoxalase domain containing 4 decreases expression EXP Amphotericin B results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr17:759,330...785,895
Ensembl chr17:757,097...782,294 		JBrowse link
G GLS glutaminase increases expression EXP Amphotericin B analog results in increased expression of GLS mRNA CTD PMID:28534445 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552 		JBrowse link
G GLUL glutamate-ammonia ligase decreases expression EXP Amphotericin B analog results in decreased expression of GLUL mRNA CTD PMID:28534445 NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206 		JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha increases expression EXP Amphotericin B analog results in increased expression of GP1BA mRNA CTD PMID:28534445 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023 		JBrowse link
G GPR20 G protein-coupled receptor 20 increases expression EXP Amphotericin B results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr 8:141,356,470...141,367,286
Ensembl chr 8:141,356,470...141,367,286 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein CTD PMID:36464106 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 increases expression EXP Amphotericin B analog results in increased expression of GRID2 mRNA CTD PMID:28534445 NCBI chr 4:92,303,966...93,810,456
Ensembl chr 4:92,303,966...93,810,157 		JBrowse link
G GRM6 glutamate metabotropic receptor 6 increases expression EXP Amphotericin B analog results in increased expression of GRM6 mRNA CTD PMID:28534445 NCBI chr 5:178,978,327...178,995,320
Ensembl chr 5:178,977,587...178,996,206 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases expression
multiple interactions		 ISO
EXP		 Amphotericin B results in decreased expression of GSTP1 mRNA
Amphotericin B inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]		 CTD PMID:20623750 PMID:23769903 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 decreases expression ISO Amphotericin B results in decreased expression of GSTT1 mRNA CTD PMID:20623750
G H2AC4 H2A clustered histone 4 decreases expression EXP Amphotericin B analog results in decreased expression of HIST1H2AC mRNA CTD PMID:28534445 NCBI chr 6:26,033,092...26,033,618
Ensembl chr 6:26,033,092...26,033,618 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
decreases activity		 EXP Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]; Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]
Amphotericin B results in decreased activity of HIF1A protein		 CTD PMID:16189267 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor multiple interactions EXP Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein] CTD PMID:16189267 NCBI chr10:100,535,943...100,559,998
Ensembl chr10:100,529,072...100,559,998 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated decreases expression EXP Amphotericin B analog results in decreased expression of HILPDA mRNA CTD PMID:28534445 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 decreases expression EXP Amphotericin B analog results in decreased expression of HIPK1 mRNA CTD PMID:28534445 NCBI chr 1:113,929,324...113,977,869
Ensembl chr 1:113,929,324...113,977,869 		JBrowse link
G HLA-F major histocompatibility complex, class I, F increases expression EXP Amphotericin B results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA CTD PMID:36464106 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Amphotericin B analog results in increased expression of HMOX1 mRNA; Amphotericin B results in increased expression of HMOX1 mRNA CTD PMID:28534445 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HOOK1 hook microtubule tethering protein 1 decreases expression EXP Amphotericin B analog results in decreased expression of HOOK1 mRNA CTD PMID:28534445 NCBI chr 1:59,814,949...59,876,322
Ensembl chr 1:59,814,786...59,876,322 		JBrowse link
G HOXD3 homeobox D3 decreases expression EXP Amphotericin B analog results in decreased expression of HOXD3 mRNA CTD PMID:28534445 NCBI chr 2:176,152,529...176,173,098
Ensembl chr 2:176,136,612...176,173,102 		JBrowse link
G HOXD4 homeobox D4 decreases expression EXP Amphotericin B analog results in decreased expression of HOXD4 mRNA CTD PMID:28534445 NCBI chr 2:176,151,550...176,153,226
Ensembl chr 2:176,151,550...176,153,226 		JBrowse link
G HPX hemopexin increases expression EXP Amphotericin B analog results in increased expression of HPX mRNA CTD PMID:28534445 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A decreases expression EXP Amphotericin B analog results in decreased expression of HSPA1A mRNA CTD PMID:28534445 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B decreases expression EXP Amphotericin B analog results in decreased expression of HSPA1B mRNA CTD PMID:28534445 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 decreases expression EXP Amphotericin B analog results in decreased expression of HSPA2 mRNA CTD PMID:28534445 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 multiple interactions EXP Amphotericin B results in increased expression of and results in increased secretion of HSPA8 protein CTD PMID:26259607 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPB3 heat shock protein family B (small) member 3 increases expression EXP Amphotericin B analog results in increased expression of HSPB3 mRNA CTD PMID:28534445 NCBI chr 5:54,455,699...54,456,377
Ensembl chr 5:54,455,699...54,456,377 		JBrowse link
G HTR3A 5-hydroxytryptamine receptor 3A increases expression EXP Amphotericin B analog results in increased expression of HTR3A mRNA CTD PMID:28534445 NCBI chr11:113,975,108...113,990,313
Ensembl chr11:113,975,075...113,990,313 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Amphotericin B analog results in increased expression of ICAM1 mRNA; Amphotericin B results in increased expression of ICAM1 mRNA CTD PMID:28534445 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID2 inhibitor of DNA binding 2 decreases expression EXP Amphotericin B analog results in decreased expression of ID2 mRNA CTD PMID:28534445 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G ID2B inhibitor of DNA binding 2B (pseudogene) decreases expression EXP Amphotericin B analog results in decreased expression of ID2B mRNA CTD PMID:28534445 NCBI chr 3:62,123,426...62,124,718 JBrowse link
G ID4 inhibitor of DNA binding 4 decreases expression EXP Amphotericin B analog results in decreased expression of ID4 mRNA; Amphotericin B results in decreased expression of ID4 mRNA CTD PMID:28534445 NCBI chr 6:19,837,370...19,842,197
Ensembl chr 6:19,837,370...19,842,197 		JBrowse link
G IFNA21 interferon alpha 21 increases expression EXP Amphotericin B analog results in increased expression of IFNA21 mRNA CTD PMID:28534445 NCBI chr 9:21,165,637...21,166,660
Ensembl chr 9:21,165,637...21,166,660 		JBrowse link
G IFNG interferon gamma multiple interactions
increases expression		 EXP [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein
Amphotericin B analog results in increased expression of IFNG mRNA		 CTD PMID:17911647 PMID:28534445 PMID:29594315 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNGR1 interferon gamma receptor 1 increases expression EXP Amphotericin B results in increased expression of IFNGR1 CTD PMID:12803856 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 decreases expression EXP Amphotericin B results in decreased expression of IGFBP5 mRNA CTD PMID:20849824 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IL10 interleukin 10 multiple interactions EXP [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein CTD PMID:17911647 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 increases expression EXP Amphotericin B analog results in increased expression of IL13RA2 mRNA CTD PMID:28534445 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL1B interleukin 1 beta increases expression EXP Amphotericin B results in increased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 decreases expression EXP Amphotericin B analog results in decreased expression of IL1R2 mRNA CTD PMID:28534445 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544 		JBrowse link
G IL1RAPL2 interleukin 1 receptor accessory protein like 2 increases expression EXP Amphotericin B analog results in increased expression of IL1RAPL2 mRNA CTD PMID:28534445 NCBI chr  X:104,566,199...105,767,829
Ensembl chr  X:104,566,199...105,767,829 		JBrowse link
G IL2 interleukin 2 multiple interactions EXP [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL6 interleukin 6 increases expression EXP Amphotericin B analog results in increased expression of IL6 mRNA CTD PMID:28534445 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBA inhibin subunit beta A increases expression EXP Amphotericin B analog results in increased expression of INHBA mRNA CTD PMID:28534445 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G INO80B INO80 complex subunit B decreases expression EXP Amphotericin B analog results in decreased expression of INO80B mRNA CTD PMID:28534445 NCBI chr 2:74,455,087...74,457,944
Ensembl chr 2:74,455,087...74,457,944 		JBrowse link
G INSIG1 insulin induced gene 1 increases expression EXP Amphotericin B analog results in increased expression of INSIG1 mRNA; Amphotericin B results in increased expression of INSIG1 mRNA CTD PMID:28534445 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G IRF5 interferon regulatory factor 5 increases expression EXP Amphotericin B analog results in increased expression of IRF5 mRNA CTD PMID:28534445 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 decreases expression EXP Amphotericin B results in decreased expression of JAG1 mRNA CTD PMID:28534445 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G KAZN kazrin, periplakin interacting protein increases expression EXP Amphotericin B analog results in increased expression of KAZN mRNA CTD PMID:28534445 NCBI chr 1:13,892,824...15,118,043
Ensembl chr 1:13,892,792...15,118,043 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 decreases expression EXP Amphotericin B analog results in decreased expression of KCNB1 mRNA CTD PMID:28534445 NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297 		JBrowse link
G KCNQ4 potassium voltage-gated channel subfamily Q member 4 decreases expression EXP Amphotericin B results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 1:40,783,787...40,840,452
Ensembl chr 1:40,783,787...40,840,452 		JBrowse link
G KLF12 KLF transcription factor 12 increases expression EXP Amphotericin B analog results in increased expression of KLF12 mRNA CTD PMID:28534445 NCBI chr13:73,686,089...74,306,045
Ensembl chr13:73,686,089...74,134,404 		JBrowse link
G KLF9 KLF transcription factor 9 decreases expression EXP Amphotericin B analog results in decreased expression of KLF9 mRNA CTD PMID:28534445 NCBI chr 9:70,384,604...70,414,657
Ensembl chr 9:70,384,604...70,414,657 		JBrowse link
G KLHL24 kelch like family member 24 decreases expression EXP Amphotericin B analog results in decreased expression of KLHL24 mRNA CTD PMID:28534445 NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519 		JBrowse link
G KLK2 kallikrein related peptidase 2 increases expression EXP Amphotericin B analog results in increased expression of KLK2 mRNA CTD PMID:28534445 NCBI chr19:50,873,439...50,880,567
Ensembl chr19:50,861,568...50,880,567 		JBrowse link
G KLRB1 killer cell lectin like receptor B1 increases expression EXP Amphotericin B analog results in increased expression of KLRB1 mRNA CTD PMID:28534445 NCBI chr12:9,594,551...9,607,916
Ensembl chr12:9,594,551...9,607,916 		JBrowse link
G KMO kynurenine 3-monooxygenase decreases expression EXP Amphotericin B analog results in decreased expression of KMO mRNA CTD PMID:28534445 NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642 		JBrowse link
G LALBA lactalbumin alpha increases expression EXP Amphotericin B analog results in increased expression of LALBA mRNA CTD PMID:28534445 NCBI chr12:48,567,684...48,571,845
Ensembl chr12:48,567,684...48,570,066 		JBrowse link
G LCN2 lipocalin 2 decreases expression EXP Amphotericin B analog results in decreased expression of LCN2 mRNA CTD PMID:28534445 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 increases expression EXP Amphotericin B analog results in increased expression of LDLRAD4 mRNA CTD PMID:28534445 NCBI chr18:13,217,682...13,652,754
Ensembl chr18:13,217,498...13,652,755 		JBrowse link
G LGALS4 galectin 4 increases expression EXP Amphotericin B analog results in increased expression of LGALS4 mRNA CTD PMID:28534445 NCBI chr19:38,801,674...38,812,945
Ensembl chr19:38,801,671...38,812,945 		JBrowse link
G LIMK1 LIM domain kinase 1 increases expression EXP Amphotericin B analog results in increased expression of LIMK1 mRNA CTD PMID:28534445 NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525 		JBrowse link
G LINC01278 long intergenic non-protein coding RNA 1278 increases expression EXP Amphotericin B analog results in increased expression of LINC01278 mRNA CTD PMID:28534445 NCBI chr  X:63,426,558...63,561,095
Ensembl chr  X:63,222,993...63,561,095 		JBrowse link
G LPIN1 lipin 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA CTD PMID:36464106 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G LSG1 large 60S subunit nuclear export GTPase 1 decreases expression EXP Amphotericin B results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr 3:194,640,791...194,672,191
Ensembl chr 3:194,640,791...194,672,463 		JBrowse link
G LYST lysosomal trafficking regulator increases expression EXP Amphotericin B analog results in increased expression of LYST mRNA CTD PMID:28534445 NCBI chr 1:235,661,031...235,883,713
Ensembl chr 1:235,661,041...235,883,724 		JBrowse link
G MADCAM1 mucosal vascular addressin cell adhesion molecule 1 increases expression EXP Amphotericin B analog results in increased expression of MADCAM1 mRNA CTD PMID:28534445 NCBI chr19:496,486...505,343
Ensembl chr19:489,176...505,343 		JBrowse link
G MAF MAF bZIP transcription factor decreases expression EXP Amphotericin B analog results in decreased expression of MAF mRNA CTD PMID:28534445 NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737 		JBrowse link
G MAOA monoamine oxidase A decreases expression EXP Amphotericin B analog results in decreased expression of MAOA mRNA CTD PMID:28534445 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression ISO Amphotericin B results in increased expression of MAP1LC3B protein CTD PMID:23988732 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAP3K19 mitogen-activated protein kinase kinase kinase 19 increases expression EXP Amphotericin B analog results in increased expression of MAP3K19 mRNA CTD PMID:28534445 NCBI chr 2:134,964,491...135,047,447
Ensembl chr 2:134,964,485...135,047,468 		JBrowse link
G MCM3AP minichromosome maintenance complex component 3 associated protein increases expression EXP Amphotericin B analog results in increased expression of MCM3AP mRNA CTD PMID:28534445 NCBI chr21:46,235,133...46,286,265
Ensembl chr21:46,235,133...46,286,297 		JBrowse link
G MEAK7 MTOR associated protein, eak-7 homolog increases expression EXP Amphotericin B analog results in increased expression of TLDC1 mRNA CTD PMID:28534445 NCBI chr16:84,476,355...84,504,659
Ensembl chr16:84,476,355...84,554,033 		JBrowse link
G MEF2C myocyte enhancer factor 2C decreases expression EXP Amphotericin B analog results in decreased expression of MEF2C mRNA CTD PMID:28534445 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MIR106B microRNA 106b increases expression EXP Amphotericin B analog results in increased expression of MIR106B CTD PMID:28534445 NCBI chr 7:100,093,993...100,094,074
Ensembl chr 7:100,093,993...100,094,074 		JBrowse link
G MIR1180 microRNA 1180 increases expression EXP Amphotericin B analog results in increased expression of MIR1180 CTD PMID:28534445 NCBI chr17:19,344,506...19,344,574
Ensembl chr17:19,344,506...19,344,574 		JBrowse link
G MIR1268A microRNA 1268a increases expression EXP Amphotericin B results in increased expression of MIR1268A CTD PMID:28534445 NCBI chr15:22,225,278...22,225,329
Ensembl chr15:22,225,278...22,225,329 		JBrowse link
G MIR1275 microRNA 1275 increases expression EXP Amphotericin B results in increased expression of MIR1275 CTD PMID:28534445 NCBI chr 6:33,999,972...34,000,051
Ensembl chr 6:33,999,972...34,000,051 		JBrowse link
G MIR138-1 microRNA 138-1 increases expression EXP Amphotericin B results in increased expression of MIR138 CTD PMID:28534445 NCBI chr 3:44,114,212...44,114,310
Ensembl chr 3:44,114,212...44,114,310 		JBrowse link
G MIR17 microRNA 17 increases expression EXP Amphotericin B analog results in increased expression of MIR17 CTD PMID:28534445 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688 		JBrowse link
G MIR181C microRNA 181c increases expression EXP Amphotericin B analog results in increased expression of MIR181C CTD PMID:28534445 NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808 		JBrowse link
G MIR181D microRNA 181d decreases expression EXP Amphotericin B analog results in decreased expression of MIR181D CTD PMID:28534445 NCBI chr19:13,874,875...13,875,011
Ensembl chr19:13,874,875...13,875,011 		JBrowse link
G MIR2277 microRNA 2277 increases expression EXP Amphotericin B results in increased expression of MIR2277 CTD PMID:28534445 NCBI chr 5:93,620,696...93,620,788
Ensembl chr 5:93,620,696...93,620,788 		JBrowse link
G MIR3141 microRNA 3141 decreases expression EXP Amphotericin B analog results in decreased expression of MIR3141 CTD PMID:28534445 NCBI chr 5:154,596,012...154,596,072
Ensembl chr 5:154,596,012...154,596,072 		JBrowse link
G MIR3153 microRNA 3153 decreases expression EXP Amphotericin B results in decreased expression of MIR3153 CTD PMID:28534445 NCBI chr 9:89,312,225...89,312,306
Ensembl chr 9:89,312,225...89,312,306 		JBrowse link
G MIR3197 microRNA 3197 decreases expression EXP Amphotericin B analog results in decreased expression of MIR3197; Amphotericin B results in decreased expression of MIR3197 CTD PMID:28534445 NCBI chr21:41,167,557...41,167,629
Ensembl chr21:41,167,557...41,167,629 		JBrowse link
G MIR320C2 microRNA 320c-2 increases expression EXP Amphotericin B analog results in increased expression of MIR320C2 CTD PMID:28534445 NCBI chr18:24,321,675...24,321,746
Ensembl chr18:24,321,686...24,321,735 		JBrowse link
G MIR320E microRNA 320e increases expression EXP Amphotericin B analog results in increased expression of MIR320E CTD PMID:28534445 NCBI chr19:46,709,282...46,709,354
Ensembl chr19:46,709,293...46,709,345 		JBrowse link
G MIR421 microRNA 421 increases expression EXP Amphotericin B analog results in increased expression of MIR421 CTD PMID:28534445 NCBI chr  X:74,218,377...74,218,461
Ensembl chr  X:74,218,377...74,218,461 		JBrowse link
G MIR423 microRNA 423 increases expression EXP Amphotericin B analog results in increased expression of MIR423; Amphotericin B results in increased expression of MIR423 CTD PMID:28534445 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172 		JBrowse link
G MIR4298 microRNA 4298 decreases expression EXP Amphotericin B analog results in decreased expression of MIR4298; Amphotericin B results in decreased expression of MIR4298 CTD PMID:28534445 NCBI chr11:1,859,464...1,859,536
Ensembl chr11:1,859,464...1,859,536 		JBrowse link
G MIR494 microRNA 494 decreases expression EXP Amphotericin B analog results in decreased expression of MIR494; Amphotericin B results in decreased expression of MIR494 CTD PMID:28534445 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MIR885 microRNA 885 decreases expression EXP Amphotericin B analog results in decreased expression of MIR885 CTD PMID:28534445 NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562 		JBrowse link
G MIR99B microRNA 99b increases expression EXP Amphotericin B analog results in increased expression of MIR99B CTD PMID:28534445 NCBI chr19:51,692,612...51,692,681
Ensembl chr19:51,692,612...51,692,681 		JBrowse link
G MIRLET7G microRNA let-7g decreases expression EXP Amphotericin B analog results in decreased expression of MIRLET7G CTD PMID:28534445 NCBI chr 3:52,268,278...52,268,361
Ensembl chr 3:52,268,278...52,268,361 		JBrowse link
G MMP28 matrix metallopeptidase 28 decreases expression EXP Amphotericin B analog results in decreased expression of MMP28 mRNA CTD PMID:28534445 NCBI chr17:35,756,249...35,795,641
Ensembl chr17:35,756,249...35,795,707 		JBrowse link
G MPHOSPH8 M-phase phosphoprotein 8 decreases expression EXP Amphotericin B analog results in decreased expression of MPHOSPH8 mRNA CTD PMID:28534445 NCBI chr13:19,633,659...19,673,441
Ensembl chr13:19,633,659...19,673,441 		JBrowse link
G MTF2 metal response element binding transcription factor 2 decreases expression EXP Amphotericin B analog results in decreased expression of MTF2 mRNA CTD PMID:28534445 NCBI chr 1:93,079,283...93,139,076
Ensembl chr 1:93,079,235...93,139,079 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming increases expression EXP Amphotericin B analog results in increased expression of MUC2 mRNA CTD PMID:28534445 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G MX2 MX dynamin like GTPase 2 increases expression EXP Amphotericin B analog results in increased expression of MX2 mRNA CTD PMID:28534445 NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393 		JBrowse link
G MYO15B myosin XVB increases expression EXP Amphotericin B analog results in increased expression of MYO15B mRNA CTD PMID:28534445 NCBI chr17:75,587,800...75,626,849
Ensembl chr17:75,587,800...75,626,849 		JBrowse link
G MYO7A myosin VIIA increases expression EXP Amphotericin B analog results in increased expression of MYO7A mRNA CTD PMID:28534445 NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241 		JBrowse link
G NAT8 N-acetyltransferase 8 (putative) decreases expression EXP Amphotericin B analog results in decreased expression of NAT8 mRNA CTD PMID:28534445 NCBI chr 2:73,640,723...73,642,422
Ensembl chr 2:73,640,723...73,642,422 		JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression EXP Amphotericin B analog results in decreased expression of NEDD9 mRNA CTD PMID:28534445 NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348 		JBrowse link
G NEFL neurofilament light chain decreases expression EXP Amphotericin B analog results in decreased expression of NEFL mRNA CTD PMID:28534445 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NEFM neurofilament medium chain decreases expression EXP Amphotericin B analog results in decreased expression of NEFM mRNA CTD PMID:28534445 NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor decreases expression EXP Amphotericin B analog results in decreased expression of NF2 mRNA CTD PMID:28534445 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598 		JBrowse link
G NOL3 nucleolar protein 3 decreases expression EXP Amphotericin B analog results in decreased expression of NOL3 mRNA CTD PMID:28534445 NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737 		JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit decreases expression EXP Amphotericin B results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 3:50,347,330...50,350,775
Ensembl chr 3:50,347,330...50,350,826 		JBrowse link
G NR2E1 nuclear receptor subfamily 2 group E member 1 increases expression EXP Amphotericin B analog results in increased expression of NR2E1 mRNA CTD PMID:28534445 NCBI chr 6:108,166,022...108,188,809
Ensembl chr 6:108,166,022...108,188,805 		JBrowse link
G NR2F1 nuclear receptor subfamily 2 group F member 1 decreases expression EXP Amphotericin B analog results in decreased expression of NR2F1 mRNA CTD PMID:28534445 NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II increases expression EXP Amphotericin B results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 decreases expression
increases expression		 EXP Amphotericin B analog results in decreased expression of NTRK2 mRNA
Amphotericin B analog results in increased expression of NTRK2 mRNA		 CTD PMID:28534445 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G OR10J1 olfactory receptor family 10 subfamily J member 1 increases expression EXP Amphotericin B analog results in increased expression of OR10J1 mRNA CTD PMID:28534445 NCBI chr 1:159,397,465...159,440,967
Ensembl chr 1:159,437,845...159,443,078 		JBrowse link
G OR2H2 olfactory receptor family 2 subfamily H member 2 increases expression EXP Amphotericin B analog results in increased expression of OR2H2 mRNA CTD PMID:28534445 NCBI chr 6:29,585,121...29,590,500
Ensembl chr 6:29,585,121...29,590,500 		JBrowse link
G OVOL2 ovo like zinc finger 2 increases expression EXP Amphotericin B analog results in increased expression of OVOL2 mRNA CTD PMID:28534445 NCBI chr20:18,024,152...18,059,188
Ensembl chr20:17,956,979...18,059,188 		JBrowse link
G PAIP1 poly(A) binding protein interacting protein 1 decreases expression EXP Amphotericin B results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758 		JBrowse link
G PARD3 par-3 family cell polarity regulator decreases expression EXP Amphotericin B results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325 		JBrowse link
G PARD6B par-6 family cell polarity regulator beta increases expression EXP Amphotericin B analog results in increased expression of PARD6B mRNA CTD PMID:28534445 NCBI chr20:50,731,580...50,753,741
Ensembl chr20:50,731,580...50,756,795 		JBrowse link
G PART1 prostate androgen-regulated transcript 1 increases expression EXP Amphotericin B results in increased expression of PART1 mRNA CTD PMID:28534445 NCBI chr 5:60,487,713...60,547,657
Ensembl chr 5:60,487,713...60,548,813 		JBrowse link
G PDE1A phosphodiesterase 1A decreases expression EXP Amphotericin B analog results in decreased expression of PDE1A mRNA CTD PMID:28534445 NCBI chr 2:182,140,041...182,716,797
Ensembl chr 2:182,139,968...182,523,359 		JBrowse link
G PDE4D phosphodiesterase 4D decreases expression EXP Amphotericin B analog results in decreased expression of PDE4D mRNA CTD PMID:28534445 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PDE4DIP phosphodiesterase 4D interacting protein decreases expression EXP Amphotericin B analog results in decreased expression of PDE4DIP mRNA CTD PMID:28534445 NCBI chr 1:148,808,434...149,033,016
Ensembl chr 1:148,808,140...149,048,286 		JBrowse link
G PDLIM7 PDZ and LIM domain 7 decreases expression EXP Amphotericin B analog results in decreased expression of PDLIM7 mRNA CTD PMID:28534445 NCBI chr 5:177,483,394...177,497,604
Ensembl chr 5:177,483,394...177,497,606 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Amphotericin B analog results in increased expression of PECAM1 mRNA CTD PMID:28534445 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PGK1 phosphoglycerate kinase 1 multiple interactions EXP Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA] CTD PMID:16189267 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP Amphotericin B analog results in decreased expression of PIK3R1 mRNA CTD PMID:28534445 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PITX2 paired like homeodomain 2 decreases expression EXP Amphotericin B analog results in decreased expression of PITX2 mRNA; Amphotericin B results in decreased expression of PITX2 mRNA CTD PMID:28534445 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
G PKLR pyruvate kinase L/R increases expression EXP Amphotericin B analog results in increased expression of PKLR mRNA CTD PMID:28534445 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438 		JBrowse link
G PKP1 plakophilin 1 increases expression EXP Amphotericin B analog results in increased expression of PKP1 mRNA CTD PMID:28534445 NCBI chr 1:201,283,506...201,332,989
Ensembl chr 1:201,283,452...201,332,993 		JBrowse link
G PLA2G2A phospholipase A2 group IIA increases expression EXP Amphotericin B analog results in increased expression of PLA2G2A mRNA CTD PMID:28534445 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G PLCB1 phospholipase C beta 1 increases expression EXP Amphotericin B analog results in increased expression of PLCB1 mRNA CTD PMID:28534445 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP Amphotericin B analog results in increased expression of PMAIP1 mRNA CTD PMID:28534445 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit increases expression EXP Amphotericin B analog results in increased expression of POLG mRNA; Amphotericin B results in increased expression of POLG mRNA CTD PMID:28534445 NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861 		JBrowse link
G POLM DNA polymerase mu increases expression EXP Amphotericin B results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr 7:44,072,062...44,082,530
Ensembl chr 7:44,072,062...44,082,530 		JBrowse link
G PPL periplakin decreases expression EXP Amphotericin B analog results in decreased expression of PPL mRNA CTD PMID:28534445 NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741 		JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C decreases expression EXP Amphotericin B analog results in decreased expression of PPP1R3C mRNA CTD PMID:28534445 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 decreases expression EXP Amphotericin B analog results in decreased expression of PSAT1 mRNA CTD PMID:28534445 NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093 		JBrowse link
G PSG11 pregnancy specific beta-1-glycoprotein 11 increases expression EXP Amphotericin B analog results in increased expression of PSG11 mRNA CTD PMID:28534445 NCBI chr19:43,007,656...43,026,469
Ensembl chr19:43,007,656...43,026,474 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 decreases expression EXP Amphotericin B analog results in decreased expression of PTPN22 mRNA CTD PMID:28534445 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T increases expression EXP Amphotericin B analog results in increased expression of PTPRT mRNA CTD PMID:28534445 NCBI chr20:42,031,890...43,189,906
Ensembl chr20:42,072,752...43,189,970 		JBrowse link
G RAD54B RAD54 homolog B increases expression EXP Amphotericin B analog results in increased expression of RAD54B mRNA CTD PMID:28534445 NCBI chr 8:94,371,960...94,475,115
Ensembl chr 8:94,371,960...94,475,115 		JBrowse link
G RAMP3 receptor activity modifying protein 3 increases expression EXP Amphotericin B analog results in increased expression of RAMP3 mRNA CTD PMID:28534445 NCBI chr 7:45,157,791...45,184,250
Ensembl chr 7:45,157,791...45,186,302 		JBrowse link
G RARRES1 retinoic acid receptor responder 1 decreases expression EXP Amphotericin B analog results in decreased expression of RARRES1 mRNA CTD PMID:28534445 NCBI chr 3:158,696,892...158,732,457
Ensembl chr 3:158,696,892...158,732,489 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 decreases expression EXP Amphotericin B analog results in decreased expression of RASGRP1 mRNA CTD PMID:28534445 NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575 		JBrowse link
G RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit decreases expression EXP Amphotericin B analog results in decreased expression of RBBP5 mRNA; Amphotericin B results in decreased expression of RBBP5 mRNA CTD PMID:28534445 NCBI chr 1:205,086,142...205,121,978
Ensembl chr 1:205,086,142...205,122,015 		JBrowse link
G RBM47 RNA binding motif protein 47 decreases expression EXP Amphotericin B analog results in decreased expression of RBM47 mRNA CTD PMID:28534445 NCBI chr 4:40,423,280...40,630,852
Ensembl chr 4:40,423,267...40,630,875 		JBrowse link
G RCAN2 regulator of calcineurin 2 decreases expression EXP Amphotericin B analog results in decreased expression of RCAN2 mRNA CTD PMID:28534445 NCBI chr 6:46,220,736...46,491,970
Ensembl chr 6:46,220,736...46,491,972 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit decreases expression EXP Amphotericin B analog results in decreased expression of REL mRNA CTD PMID:28534445 NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612 		JBrowse link
G REPS2 RALBP1 associated Eps domain containing 2 decreases expression EXP Amphotericin B analog results in decreased expression of REPS2 mRNA CTD PMID:28534445 NCBI chr  X:16,946,658...17,196,655
Ensembl chr  X:16,946,658...17,153,272 		JBrowse link
G RGS2 regulator of G protein signaling 2 decreases expression EXP Amphotericin B analog results in decreased expression of RGS2 mRNA; Amphotericin B results in decreased expression of RGS2 mRNA CTD PMID:28534445 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275 		JBrowse link
G RHD Rh blood group D antigen increases expression EXP Amphotericin B analog results in increased expression of RHD mRNA CTD PMID:28534445 NCBI chr 1:25,272,486...25,330,445
Ensembl chr 1:25,272,393...25,330,445 		JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 decreases expression EXP Amphotericin B analog results in decreased expression of FAM65B mRNA; Amphotericin B results in decreased expression of FAM65B mRNA CTD PMID:28534445 NCBI chr 6:24,804,284...25,042,168
Ensembl chr 6:24,804,282...25,042,170 		JBrowse link
G RMND5A required for meiotic nuclear division 5 homolog A decreases expression EXP Amphotericin B analog results in decreased expression of RMND5A mRNA CTD PMID:28534445 NCBI chr 2:86,720,291...86,778,041
Ensembl chr 2:86,720,291...86,778,041 		JBrowse link
G RNASE4 ribonuclease A family member 4 decreases expression EXP Amphotericin B analog results in decreased expression of RNASE4 mRNA CTD PMID:28534445 NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216 		JBrowse link
G RND3 Rho family GTPase 3 increases expression EXP Amphotericin B results in increased expression of RND3 mRNA CTD PMID:28534445 NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011 		JBrowse link
G RORA RAR related orphan receptor A decreases expression EXP Amphotericin B analog results in decreased expression of RORA mRNA CTD PMID:28534445 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G RPS10P2 ribosomal protein S10 pseudogene 2 increases expression EXP Amphotericin B analog results in increased expression of RPS10P2 mRNA CTD PMID:28534445 NCBI chr20:14,757,533...14,758,108
Ensembl chr20:14,757,563...14,758,056 		JBrowse link
G RPS8 ribosomal protein S8 increases expression EXP Amphotericin B analog results in increased expression of RPS8 mRNA CTD PMID:28534445 NCBI chr 1:44,775,540...44,778,779
Ensembl chr 1:44,775,251...44,778,779 		JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator decreases expression EXP Amphotericin B analog results in decreased expression of RRAD mRNA CTD PMID:28534445 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535 		JBrowse link
G RSL1D1 ribosomal L1 domain containing 1 decreases expression EXP Amphotericin B analog results in decreased expression of RSL1D1 mRNA CTD PMID:28534445 NCBI chr16:11,833,850...11,851,542
Ensembl chr16:11,833,850...11,851,580 		JBrowse link
G RTN1 reticulon 1 decreases expression EXP Amphotericin B analog results in decreased expression of RTN1 mRNA CTD PMID:28534445 NCBI chr14:59,595,976...59,870,776
Ensembl chr14:59,595,976...59,870,776 		JBrowse link
G RUNX3 RUNX family transcription factor 3 decreases expression EXP Amphotericin B results in decreased expression of RUNX3 mRNA CTD PMID:20849824 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G SAP30 Sin3A associated protein 30 increases expression EXP Amphotericin B analog results in increased expression of SAP30 mRNA CTD PMID:28534445 NCBI chr 4:173,370,954...173,377,532
Ensembl chr 4:173,369,969...173,377,532 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha decreases expression EXP Amphotericin B analog results in decreased expression of SCNN1A mRNA CTD PMID:28534445 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SERPINA5 serpin family A member 5 decreases expression EXP Amphotericin B analog results in decreased expression of SERPINA5 mRNA CTD PMID:28534445 NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118 		JBrowse link
G SERPINB4 serpin family B member 4 decreases expression EXP Amphotericin B analog results in decreased expression of SERPINB4 mRNA CTD PMID:28534445 NCBI chr18:63,637,259...63,644,256
Ensembl chr18:63,637,259...63,644,256 		JBrowse link
G SGK3 serum/glucocorticoid regulated kinase family member 3 decreases expression EXP Amphotericin B results in decreased expression of SGK3 mRNA CTD PMID:28534445 NCBI chr 8:66,712,781...66,862,022
Ensembl chr 8:66,712,734...66,862,022 		JBrowse link
G SIGLEC1 sialic acid binding Ig like lectin 1 increases expression EXP Amphotericin B analog results in increased expression of SIGLEC1 mRNA CTD PMID:28534445 NCBI chr20:3,686,970...3,712,600
Ensembl chr20:3,686,970...3,712,600 		JBrowse link
G SIK1 salt inducible kinase 1 increases expression EXP Amphotericin B analog results in increased expression of SIK1 mRNA; Amphotericin B results in increased expression of SIK1 mRNA CTD PMID:28534445 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131 		JBrowse link
G SLC16A6 solute carrier family 16 member 6 increases expression EXP Amphotericin B analog results in increased expression of SLC16A6 mRNA CTD PMID:28534445 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267 		JBrowse link
G SLC22A14 solute carrier family 22 member 14 increases expression EXP Amphotericin B analog results in increased expression of SLC22A14 mRNA CTD PMID:28534445 NCBI chr 3:38,278,832...38,318,575
Ensembl chr 3:38,282,294...38,318,575 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SLC22A7 mRNA CTD PMID:36464106 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC27A2 solute carrier family 27 member 2 decreases expression EXP Amphotericin B analog results in decreased expression of SLC27A2 mRNA CTD PMID:28534445 NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385 		JBrowse link
G SLC2A5 solute carrier family 2 member 5 decreases expression EXP Amphotericin B analog results in decreased expression of SLC2A5 mRNA CTD PMID:28534445 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478 		JBrowse link
G SLC39A7 solute carrier family 39 member 7 decreases expression EXP Amphotericin B analog results in decreased expression of SLC39A7 mRNA CTD PMID:28534445 NCBI chr 6:33,200,867...33,204,437
Ensembl chr 6:33,200,305...33,204,439 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 increases expression EXP Amphotericin B analog results in increased expression of SLC5A1 mRNA CTD PMID:28534445 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SLC6A6 solute carrier family 6 member 6 decreases expression EXP Amphotericin B analog results in decreased expression of SLC6A6 mRNA CTD PMID:28534445 NCBI chr 3:14,402,576...14,489,349
Ensembl chr 3:14,402,576...14,489,349 		JBrowse link
G SLIT1 slit guidance ligand 1 decreases expression EXP Amphotericin B results in decreased expression of SLIT1 mRNA CTD PMID:20849824 NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 decreases expression EXP Amphotericin B analog results in decreased expression of SORBS1 mRNA CTD PMID:28534445 NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414 		JBrowse link
G SORL1 sortilin related receptor 1 decreases expression EXP Amphotericin B analog results in decreased expression of SORL1 mRNA CTD PMID:28534445 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763 		JBrowse link
G SPAG8 sperm associated antigen 8 decreases expression EXP Amphotericin B analog results in decreased expression of SPAG8 mRNA CTD PMID:28534445 NCBI chr 9:35,807,785...35,812,262
Ensembl chr 9:35,808,045...35,812,272 		JBrowse link
G SPP1 secreted phosphoprotein 1 affects expression ISO Amphotericin B affects the expression of SPP1 mRNA CTD PMID:20623750 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 decreases expression EXP Amphotericin B analog results in decreased expression of SPRY1 mRNA CTD PMID:28534445 NCBI chr 4:123,396,795...123,403,760
Ensembl chr 4:123,396,795...123,403,760 		JBrowse link
G SPTBN5 spectrin beta, non-erythrocytic 5 increases expression EXP Amphotericin B analog results in increased expression of SPTBN5 mRNA CTD PMID:28534445 NCBI chr15:41,848,146...41,894,053
Ensembl chr15:41,848,146...41,894,053 		JBrowse link
G SQLE squalene epoxidase multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SQLE mRNA CTD PMID:36464106 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF2 mRNA CTD PMID:36464106 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STC1 stanniocalcin 1 decreases expression EXP Amphotericin B analog results in decreased expression of STC1 mRNA CTD PMID:28534445 NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806 		JBrowse link
G STMN4 stathmin 4 increases expression EXP Amphotericin B analog results in increased expression of STMN4 mRNA CTD PMID:28534445 NCBI chr 8:27,235,308...27,258,404
Ensembl chr 8:27,235,308...27,258,420 		JBrowse link
G TAC3 tachykinin precursor 3 increases expression EXP Amphotericin B analog results in increased expression of TAC3 mRNA CTD PMID:28534445 NCBI chr12:57,010,000...57,016,529
Ensembl chr12:57,010,000...57,028,883 		JBrowse link
G TACSTD2 tumor associated calcium signal transducer 2 decreases expression EXP Amphotericin B analog results in decreased expression of TACSTD2 mRNA CTD PMID:28534445 NCBI chr 1:58,575,433...58,577,252
Ensembl chr 1:58,575,433...58,577,252 		JBrowse link
G TAF13 TATA-box binding protein associated factor 13 decreases expression EXP Amphotericin B analog results in decreased expression of TAF13 mRNA CTD PMID:28534445 NCBI chr 1:109,064,140...109,076,003
Ensembl chr 1:109,062,496...109,076,012 		JBrowse link
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor increases expression EXP Amphotericin B analog results in increased expression of TAL1 mRNA CTD PMID:28534445 NCBI chr 1:47,216,290...47,232,335
Ensembl chr 1:47,216,290...47,232,225 		JBrowse link
G TCF20 transcription factor 20 increases expression EXP Amphotericin B analog results in increased expression of TCF20 mRNA CTD PMID:28534445 NCBI chr22:42,160,013...42,343,537
Ensembl chr22:42,160,013...42,343,616 		JBrowse link
G TCN1 transcobalamin 1 decreases expression EXP Amphotericin B analog results in decreased expression of TCN1 mRNA CTD PMID:28534445 NCBI chr11:59,852,808...59,866,487
Ensembl chr11:59,852,800...59,866,489 		JBrowse link
G TENM1 teneurin transmembrane protein 1 decreases expression EXP Amphotericin B analog results in decreased expression of TENM1 mRNA CTD PMID:28534445 NCBI chr  X:124,375,903...125,204,312
Ensembl chr  X:124,375,903...125,204,312 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A decreases expression EXP Amphotericin B analog results in decreased expression of FAM46A mRNA CTD PMID:28534445 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774 		JBrowse link
G TFDP2 transcription factor Dp-2 decreases expression EXP Amphotericin B analog results in decreased expression of TFDP2 mRNA; Amphotericin B results in decreased expression of TFDP2 mRNA CTD PMID:28534445 NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544 		JBrowse link
G TFEC transcription factor EC decreases expression EXP Amphotericin B analog results in decreased expression of TFEC mRNA CTD PMID:28534445 NCBI chr 7:115,935,152...116,159,896
Ensembl chr 7:115,935,148...116,159,896 		JBrowse link
G TFF1 trefoil factor 1 increases expression EXP Amphotericin B analog results in increased expression of TFF1 mRNA CTD PMID:28534445 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein CTD PMID:17911647 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G THEMIS2 thymocyte selection associated family member 2 decreases expression EXP Amphotericin B analog results in decreased expression of THEMIS2 mRNA CTD PMID:28534445 NCBI chr 1:27,872,544...27,886,675
Ensembl chr 1:27,872,543...27,886,685 		JBrowse link
G TMCC1 transmembrane and coiled-coil domain family 1 decreases expression EXP Amphotericin B analog results in decreased expression of TMCC1 mRNA CTD PMID:28534445 NCBI chr 3:129,647,792...129,893,711
Ensembl chr 3:129,647,792...129,893,711 		JBrowse link
G TMEM140 transmembrane protein 140 decreases expression EXP Amphotericin B analog results in decreased expression of TMEM140 mRNA CTD PMID:28534445 NCBI chr 7:135,148,072...135,166,215
Ensembl chr 7:135,148,072...135,166,215 		JBrowse link
G TMEM151B transmembrane protein 151B increases expression EXP Amphotericin B results in increased expression of TMEM151B mRNA CTD PMID:28534445 NCBI chr 6:44,270,450...44,279,444
Ensembl chr 6:44,270,450...44,307,506 		JBrowse link
G TMEM176B transmembrane protein 176B decreases expression EXP Amphotericin B analog results in decreased expression of TMEM176B mRNA CTD PMID:28534445 NCBI chr 7:150,791,301...150,801,360
Ensembl chr 7:150,791,285...150,801,360 		JBrowse link
G TMEM255A transmembrane protein 255A decreases expression EXP Amphotericin B analog results in decreased expression of TMEM255A mRNA CTD PMID:28534445 NCBI chr  X:120,251,433...120,311,461
Ensembl chr  X:120,258,650...120,311,556 		JBrowse link
G TMEM45A transmembrane protein 45A decreases expression EXP Amphotericin B analog results in decreased expression of TMEM45A mRNA CTD PMID:28534445 NCBI chr 3:100,492,619...100,577,444
Ensembl chr 3:100,492,619...100,577,444 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 increases expression EXP Amphotericin B results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116 		JBrowse link
G TNF tumor necrosis factor increases expression ISO Amphotericin B results in increased expression of TNF mRNA CTD PMID:20623750 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 increases expression EXP Amphotericin B analog results in increased expression of TNFAIP3 mRNA CTD PMID:28534445 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFSF4 TNF superfamily member 4 decreases expression EXP Amphotericin B analog results in decreased expression of TNFSF4 mRNA CTD PMID:28534445 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
G TOX3 TOX high mobility group box family member 3 decreases expression EXP Amphotericin B analog results in decreased expression of TOX3 mRNA CTD PMID:28534445 NCBI chr16:52,436,416...52,547,802
Ensembl chr16:52,436,417...52,547,802 		JBrowse link
G TP63 tumor protein p63 increases expression EXP Amphotericin B analog results in increased expression of TP63 mRNA CTD PMID:28534445 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276 		JBrowse link
G TRAV10 T cell receptor alpha variable 10 increases expression EXP Amphotericin B analog results in increased expression of TRAV10 mRNA CTD PMID:28534445 NCBI chr14:21,825,508...21,826,075
Ensembl chr14:21,825,472...21,826,075 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 decreases expression EXP Amphotericin B analog results in decreased expression of TREM1 mRNA CTD PMID:28534445 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
G TRPM3 transient receptor potential cation channel subfamily M member 3 decreases expression EXP Amphotericin B analog results in decreased expression of TRPM3 mRNA CTD PMID:28534445 NCBI chr 9:70,529,060...71,446,971
Ensembl chr 9:70,529,060...71,446,904 		JBrowse link
G TRPM6 transient receptor potential cation channel subfamily M member 6 increases expression EXP Amphotericin B analog results in increased expression of TRPM6 mRNA CTD PMID:28534445 NCBI chr 9:74,722,495...74,887,921
Ensembl chr 9:74,722,495...74,888,094 		JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 decreases expression EXP Amphotericin B analog results in decreased expression of TRPS1 mRNA CTD PMID:28534445 NCBI chr 8:115,408,496...115,668,975
Ensembl chr 8:115,408,496...115,809,673 		JBrowse link
G TSSK2 testis specific serine kinase 2 increases expression EXP Amphotericin B analog results in increased expression of TSSK2 mRNA CTD PMID:28534445 NCBI chr22:19,131,308...19,132,622
Ensembl chr22:19,131,308...19,132,622 		JBrowse link
G TTTY2 testis expressed transcript, Y-linked 2 increases expression EXP Amphotericin B analog results in increased expression of TTTY2 mRNA CTD PMID:28534445 NCBI chr  Y:9,736,286...9,758,476
Ensembl chr  Y:9,740,584...9,758,476 		JBrowse link
G TTTY2B testis expressed transcript, Y-linked 2B increases expression EXP Amphotericin B analog results in increased expression of TTTY2B mRNA CTD PMID:28534445 NCBI chr  Y:6,406,244...6,428,444
Ensembl chr  Y:6,406,244...6,462,091 		JBrowse link
G TXNIP thioredoxin interacting protein decreases expression EXP Amphotericin B analog results in decreased expression of TXNIP mRNA CTD PMID:28534445 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) increases expression EXP Amphotericin B analog results in increased expression of UBE2D4 mRNA CTD PMID:28534445 NCBI chr 7:43,926,436...43,956,136
Ensembl chr 7:43,926,436...43,956,136 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 affects expression ISO Amphotericin B affects the expression of UGT1A9 mRNA CTD PMID:20623750 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G USP2 ubiquitin specific peptidase 2 increases expression EXP Amphotericin B analog results in increased expression of USP2 mRNA CTD PMID:28534445 NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711 		JBrowse link
G USP36 ubiquitin specific peptidase 36 increases expression EXP Amphotericin B results in increased expression of USP36 mRNA CTD PMID:20849824 NCBI chr17:78,787,381...78,841,439
Ensembl chr17:78,787,381...78,841,441 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 decreases expression EXP Amphotericin B analog results in decreased expression of VAV3 mRNA; Amphotericin B results in decreased expression of VAV3 mRNA CTD PMID:28534445 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
G VGLL1 vestigial like family member 1 increases expression EXP Amphotericin B analog results in increased expression of VGLL1 mRNA CTD PMID:28534445 NCBI chr  X:136,532,215...136,556,799
Ensembl chr  X:136,532,215...136,556,807 		JBrowse link
G VNN1 vanin 1 decreases expression EXP Amphotericin B analog results in decreased expression of VNN1 mRNA CTD PMID:28534445 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055 		JBrowse link
G XPNPEP2 X-prolyl aminopeptidase 2 increases expression EXP Amphotericin B analog results in increased expression of XPNPEP2 mRNA CTD PMID:28534445 NCBI chr  X:129,738,979...129,769,536
Ensembl chr  X:129,738,949...129,769,536 		JBrowse link
G ZBED2 zinc finger BED-type containing 2 decreases expression EXP Amphotericin B results in decreased expression of ZBED2 mRNA CTD PMID:28534445 NCBI chr 3:111,592,900...111,595,346
Ensembl chr 3:111,592,900...111,595,346 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 decreases expression EXP Amphotericin B analog results in decreased expression of ZBTB16 mRNA CTD PMID:28534445 NCBI chr11:114,059,711...114,256,770
Ensembl chr11:114,059,041...114,256,765 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 decreases expression EXP Amphotericin B analog results in decreased expression of ZFP36L2 mRNA CTD PMID:28534445 NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606 		JBrowse link
G ZFX zinc finger protein X-linked decreases expression EXP Amphotericin B results in decreased expression of ZFX mRNA CTD PMID:28534445 NCBI chr  X:24,148,982...24,216,255
Ensembl chr  X:24,149,173...24,216,255 		JBrowse link
G ZFY zinc finger protein Y-linked decreases expression EXP Amphotericin B results in decreased expression of ZFY mRNA CTD PMID:28534445 NCBI chr  Y:2,935,381...2,982,506
Ensembl chr  Y:2,935,281...2,982,506 		JBrowse link
G ZMAT4 zinc finger matrin-type 4 increases expression EXP Amphotericin B analog results in increased expression of ZMAT4 mRNA CTD PMID:28534445 NCBI chr 8:40,530,590...40,897,826
Ensembl chr 8:40,530,590...40,897,833 		JBrowse link
G ZNF155 zinc finger protein 155 decreases expression EXP Amphotericin B analog results in decreased expression of ZNF155 mRNA CTD PMID:28534445 NCBI chr19:43,984,188...43,998,326
Ensembl chr19:43,967,862...43,998,326 		JBrowse link
G ZNF224 zinc finger protein 224 decreases expression EXP Amphotericin B analog results in decreased expression of ZNF224 mRNA CTD PMID:28534445 NCBI chr19:44,094,361...44,109,826
Ensembl chr19:44,094,361...44,109,886 		JBrowse link
G ZNF236 zinc finger protein 236 increases expression EXP Amphotericin B analog results in increased expression of ZNF236 mRNA CTD PMID:28534445 NCBI chr18:76,822,557...76,972,901
Ensembl chr18:76,822,557...76,972,901 		JBrowse link
G ZNF343 zinc finger protein 343 increases expression EXP Amphotericin B analog results in increased expression of ZNF343 mRNA; Amphotericin B results in increased expression of ZNF343 mRNA CTD PMID:28534445 NCBI chr20:2,481,817...2,524,999
Ensembl chr20:2,481,817...2,524,702 		JBrowse link
G ZNF652 zinc finger protein 652 decreases expression EXP Amphotericin B results in decreased expression of ZNF652 mRNA CTD PMID:28534445 NCBI chr17:49,288,117...49,362,473
Ensembl chr17:49,289,206...49,362,473 		JBrowse link
G ZNF671 zinc finger protein 671 decreases expression EXP Amphotericin B results in decreased expression of ZNF671 mRNA CTD PMID:20849824 NCBI chr19:57,719,751...57,727,624
Ensembl chr19:57,719,751...57,727,624 		JBrowse link
amphotericin B methyl ester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR1 hepatitis A virus cellular receptor 1 increases expression ISO methylamphotericin B results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G LCN2 lipocalin 2 increases expression ISO methylamphotericin B results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression ISO methylamphotericin B results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression ISO methylamphotericin B results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
azithromycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP Azithromycin inhibits the reaction [Transforming Growth Factor beta1 results in increased expression of ACTA2 protein] CTD PMID:36581200 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G AIF1 allograft inflammatory factor 1 increases expression ISO Azithromycin results in increased expression of AIF1 mRNA CTD PMID:37995777 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G ARG1 arginase 1 increases expression ISO Azithromycin results in increased expression of ARG1 protein CTD PMID:20231397 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G ARSA arylsulfatase A increases activity ISO Azithromycin results in increased activity of ARSA protein CTD PMID:8830663 NCBI chr22:50,622,754...50,628,152
Ensembl chr22:50,622,754...50,628,173 		JBrowse link
G CASP3 caspase 3 decreases expression ISO Azithromycin results in decreased expression of CASP3 mRNA CTD PMID:37995777 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression ISO Azithromycin results in decreased expression of CCL2 protein CTD PMID:20231397 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CDH2 cadherin 2 multiple interactions EXP Azithromycin inhibits the reaction [Transforming Growth Factor beta1 results in increased expression of CDH2 protein] CTD PMID:36581200 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CTNNB1 catenin beta 1 decreases expression ISO Azithromycin results in decreased expression of CTNNB1 mRNA CTD PMID:37995777 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CTSB cathepsin B multiple interactions
increases activity		 ISO Cycloheximide inhibits the reaction [Azithromycin results in increased activity of CTSB protein] CTD PMID:8830663 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Azithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; Azithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein] CTD PMID:21417583 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
decreases activity		 EXP Azithromycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]
Azithromycin results in decreased activity of CYP3A4 protein		 CTD PMID:16416302 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 decreases expression ISO Azithromycin results in decreased expression of DLG4 protein CTD PMID:37995777 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Azithromycin results in increased expression of FOS mRNA; Azithromycin results in increased expression of FOS protein CTD PMID:32454074 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GFAP glial fibrillary acidic protein increases expression ISO Azithromycin results in increased expression of GFAP mRNA CTD PMID:37995777 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GHSR growth hormone secretagogue receptor increases expression EXP Azithromycin results in increased expression of GHSR mRNA; Azithromycin results in increased expression of GHSR protein CTD PMID:37100089 NCBI chr 3:172,443,291...172,448,456
Ensembl chr 3:172,443,291...172,448,456 		JBrowse link
G HEXB hexosaminidase subunit beta increases activity ISO Azithromycin results in increased activity of HEXB protein CTD PMID:8830663 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647 		JBrowse link
G IL1B interleukin 1 beta decreases expression
multiple interactions		 ISO Azithromycin results in decreased expression of IL1B protein
Azithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Azithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]		 CTD PMID:18435685 PMID:21195124 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 decreases expression ISO Azithromycin results in decreased expression of IL6 protein CTD PMID:20231397 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAP2 microtubule associated protein 2 decreases expression ISO Azithromycin results in decreased expression of MAP2 mRNA CTD PMID:37995777 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MKI67 marker of proliferation Ki-67 decreases expression ISO Azithromycin results in decreased expression of MKI67 mRNA CTD PMID:37995777 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP1 matrix metallopeptidase 1 decreases secretion
increases secretion		 EXP Azithromycin results in decreased secretion of MMP1 protein
Azithromycin results in increased secretion of MMP1 protein		 CTD PMID:24890593 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP3 matrix metallopeptidase 3 decreases secretion
increases secretion		 EXP Azithromycin results in decreased secretion of MMP3 protein
Azithromycin results in increased secretion of MMP3 protein		 CTD PMID:24890593 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G P2RY12 purinergic receptor P2Y12 decreases expression ISO Azithromycin results in decreased expression of P2RY12 mRNA CTD PMID:37995777 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G PLA1A phospholipase A1 member A increases activity ISO Azithromycin results in increased activity of PLA1A protein CTD PMID:8830663 NCBI chr 3:119,597,885...119,629,811
Ensembl chr 3:119,597,875...119,629,811 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions EXP Azithromycin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein] CTD PMID:21417583 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RACK1 receptor for activated C kinase 1 multiple interactions EXP Azithromycin inhibits the reaction [Transforming Growth Factor beta1 results in increased expression of RACK1 protein] CTD PMID:36581200 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096 		JBrowse link
G RBFOX3 RNA binding fox-1 homolog 3 decreases expression ISO Azithromycin results in decreased expression of RBFOX3 protein CTD PMID:37995777 NCBI chr17:79,089,345...79,665,571
Ensembl chr17:79,089,345...79,611,051 		JBrowse link
G S100B S100 calcium binding protein B increases expression ISO Azithromycin results in increased expression of S100B mRNA CTD PMID:37995777 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Azithromycin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP Azithromycin inhibits the reaction [Transforming Growth Factor beta1 results in increased phosphorylation of SMAD3 protein] CTD PMID:36581200 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SOX2 SRY-box transcription factor 2 decreases expression ISO Azithromycin results in decreased expression of SOX2 mRNA; Azithromycin results in decreased expression of SOX2 protein CTD PMID:37995777 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G TNF tumor necrosis factor decreases expression ISO Azithromycin results in decreased expression of TNF protein CTD PMID:20231397 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G WNT3 Wnt family member 3 decreases expression ISO Azithromycin results in decreased expression of WNT3 mRNA CTD PMID:37995777 NCBI chr17:46,762,506...46,818,692
Ensembl chr17:46,762,506...46,833,154 		JBrowse link
bafilomycin A1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions ISO bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AIM2 absent in melanoma 2 multiple interactions EXP [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of AIM2 protein CTD PMID:32645460 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,061,599...159,187,843 		JBrowse link
G AKT1S1 AKT1 substrate 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] CTD PMID:22689575 NCBI chr19:49,869,033...49,878,356
Ensembl chr19:49,869,033...49,878,459 		JBrowse link
G ALB albumin decreases uptake EXP bafilomycin A1 results in decreased uptake of ALB protein CTD PMID:16313995 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression EXP bafilomycin A1 results in increased expression of APAF1 protein CTD PMID:28483490 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G ARF6 ADP ribosylation factor 6 multiple interactions ISO bafilomycin A1 inhibits the reaction [maduramicin results in decreased expression of ARF6 protein] CTD PMID:37394175 NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,079...49,897,054 		JBrowse link
G ASIC1 acid sensing ion channel subunit 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] CTD PMID:16769263 NCBI chr12:50,057,596...50,083,622
Ensembl chr12:50,057,548...50,083,611 		JBrowse link
G ATG5 autophagy related 5 multiple interactions EXP
ISO		 ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]
[bafilomycin A1 co-treated with Swainsonine] results in increased expression of ATG5 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of ATG5 protein		 CTD PMID:29938581 PMID:36402259 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP bafilomycin A1 inhibits the reaction [Hydroxychloroquine results in increased activity of BAX protein] CTD PMID:12813466 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions		 ISO bafilomycin A1 results in decreased expression of BCL2 mRNA
bafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]		 CTD PMID:31310755 PMID:34374793 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BECN1 beclin 1 multiple interactions
increases expression		 EXP
ISO		 bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein]
[Swainsonine co-treated with bafilomycin A1] results in increased expression of BECN1 protein; bafilomycin A1 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BECN1 protein]
bafilomycin A1 results in increased expression of BECN1 protein		 CTD PMID:32645460 PMID:33186601 PMID:33242459 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions EXP bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:23111315 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BID BH3 interacting domain death agonist increases expression
multiple interactions
increases cleavage		 ISO
EXP		 bafilomycin A1 results in increased expression of BID protein modified form
vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein]
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]		 CTD PMID:26853465 PMID:28378122 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression
multiple interactions		 EXP bafilomycin A1 results in increased expression of BNIP3 mRNA; bafilomycin A1 results in increased expression of BNIP3 protein
BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; capivasertib affects the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; Lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; vistusertib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]		 CTD PMID:25981168 PMID:26853465 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G CASP3 caspase 3 decreases activity
increases cleavage
multiple interactions
increases activity		 EXP
ISO		 bafilomycin A1 results in decreased activity of CASP3 protein
bafilomycin A1 results in increased cleavage of CASP3 protein
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]
bafilomycin A1 results in increased activity of CASP3 protein
[Swainsonine co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]
[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; [bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein]		 CTD PMID:20876807 PMID:23380477 PMID:24321340 PMID:24889822 PMID:25266202 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP4 caspase 4 increases activity EXP bafilomycin A1 results in increased activity of CASP4 protein CTD PMID:20371669 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CASP7 caspase 7 increases activity
decreases activity		 EXP bafilomycin A1 results in increased activity of CASP7 protein
bafilomycin A1 results in decreased activity of CASP7 protein		 CTD PMID:20371669 PMID:25981168 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 multiple interactions ISO bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]		 CTD PMID:28378122 PMID:29111403 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions ISO
EXP		 bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP9 protein]		 CTD PMID:28378122 PMID:30240709 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCND1 cyclin D1 multiple interactions EXP bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of CCND1 protein] CTD PMID:33359579 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDC25C cell division cycle 25C multiple interactions EXP bafilomycin A1 inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] CTD PMID:29074359 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDH1 cadherin 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [Capsaicin results in increased expression of CDH1 protein] CTD PMID:36044967 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH2 cadherin 2 multiple interactions EXP bafilomycin A1 inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein] CTD PMID:36044967 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CTSB cathepsin B multiple interactions EXP bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]; bafilomycin A1 inhibits the reaction [Hydroxychloroquine affects the localization of CTSB protein] CTD PMID:12813466 PMID:23380477 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D decreases cleavage EXP bafilomycin A1 results in decreased cleavage of CTSD protein CTD PMID:36070022 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSL cathepsin L decreases cleavage EXP bafilomycin A1 results in decreased cleavage of CTSL protein CTD PMID:36070022 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions EXP bafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:26682054 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions
increases expression		 ISO [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein
bafilomycin A1 results in increased expression of DDIT4 protein		 CTD PMID:22689575 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G EGF epidermal growth factor multiple interactions ISO [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Aspartic Acid; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Taurine; [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein; bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine] CTD PMID:22689575 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:22689575 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G EPOR erythropoietin receptor multiple interactions EXP bafilomycin A1 inhibits the reaction [Aristolochic Acids results in increased degradation of and results in decreased expression of EPOR protein] CTD PMID:26136230 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G FASLG Fas ligand multiple interactions ISO bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]		 CTD PMID:20200208 PMID:28378122 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog multiple interactions EXP bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] CTD PMID:29371327 NCBI chr 7:139,340,472...139,346,328
Ensembl chr 7:139,339,457...139,346,328 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions ISO bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased acetylation of FOXO1 protein]] CTD PMID:24889822 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FTH1 ferritin heavy chain 1 multiple interactions EXP bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTH1 protein] CTD PMID:37951334 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G FTL ferritin light chain multiple interactions EXP bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTL protein] CTD PMID:37951334 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879 		JBrowse link
G GJA1 gap junction protein alpha 1 increases expression EXP bafilomycin A1 results in increased expression of GJA1 protein CTD PMID:35750204 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 EXP bafilomycin A1 results in increased expression of HIF1A protein
HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]		 CTD PMID:25981168 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HMOX1 heme oxygenase 1 decreases expression
multiple interactions		 EXP bafilomycin A1 results in decreased expression of HMOX1 protein
[bafilomycin A1 co-treated with methanandamide] results in increased expression of HMOX1 protein; [bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; bafilomycin A1 inhibits the reaction [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of HMOX1 protein]		 CTD PMID:29796178 PMID:33076330 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IFNG interferon gamma decreases expression ISO bafilomycin A1 results in decreased expression of IFNG mRNA CTD PMID:16932910 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1B interleukin 1 beta decreases expression
multiple interactions		 ISO
EXP		 bafilomycin A1 results in decreased expression of IL1B mRNA
[bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]		 CTD PMID:16932910 PMID:24158569 PMID:32645460 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 increases expression ISO bafilomycin A1 results in increased expression of IL6 mRNA CTD PMID:16932910 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS insulin multiple interactions ISO bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22689575 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions EXP bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] CTD PMID:32283200 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions EXP bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 increases expression
multiple interactions		 ISO bafilomycin A1 results in increased expression of LAMP1 protein
[bafilomycin A1 co-treated with Swainsonine] results in increased expression of LAMP1 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased expression of LAMP1 protein		 CTD PMID:36402259 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase multiple interactions ISO bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] CTD PMID:32278738 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 increases response to substance EXP LRRK2 gene mutant form results in increased susceptibility to bafilomycin A1 CTD PMID:25017139 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G MAN2A1 mannosidase alpha class 2A member 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Swainsonine results in decreased expression of MAN2A1 mRNA] CTD PMID:36402259 NCBI chr 5:109,689,927...109,869,625
Ensembl chr 5:109,689,927...109,869,625 		JBrowse link
G MAN2B1 mannosidase alpha class 2B member 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Swainsonine results in decreased expression of MAN2B1 mRNA] CTD PMID:36402259 NCBI chr19:12,646,512...12,666,742
Ensembl chr19:12,646,511...12,666,742 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha multiple interactions
increases expression		 ISO
EXP		 bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein]
bafilomycin A1 results in increased expression of MAP1LC3A protein modified form		 CTD PMID:30871063 PMID:31120128 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases lipidation
increases expression
increases cleavage
decreases degradation		 EXP
ISO		 [bafilomycin A1 co-treated with Miconazole] results in increased expression of MAP1LC3B protein; [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [[alpha-Chlorohydrin co-treated with Diosgenin] results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [metarrestin results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Miconazole results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ovatodiolide results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [Sevoflurane results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 results in increased expression of and results in increased lipidation of MAP1LC3B protein; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
bafilomycin A1 results in increased lipidation of MAP1LC3B protein
[Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 inhibits the reaction [olaparib inhibits the reaction [Hydrogen Peroxide results in increased lipidation of MAP1LC3B protein]]; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form]
bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
[bafilomycin A1 co-treated with Swainsonine] results in increased expression of MAP1LC3B mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [tricalcium phosphate results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein]
bafilomycin A1 results in increased cleavage of MAP1LC3B protein
bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form
bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form		 CTD PMID:23880069 PMID:24145604 PMID:25301941 PMID:26459185 PMID:26853465 More... NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases expression		 EXP bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK1 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein]
bafilomycin A1 results in increased expression of MAPK1 protein modified form		 CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases expression		 EXP bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK3 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK3 protein]
bafilomycin A1 results in increased expression of MAPK3 protein modified form		 CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation ISO bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases phosphorylation ISO bafilomycin A1 results in decreased phosphorylation of MTOR protein CTD PMID:31310755 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTTP microsomal triglyceride transfer protein increases expression EXP bafilomycin A1 results in increased expression of MTTP protein CTD PMID:34516972 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G NCOA4 nuclear receptor coactivator 4 multiple interactions EXP bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of NCOA4 protein] CTD PMID:37951334 NCBI chr10:46,005,088...46,030,623
Ensembl chr10:46,005,088...46,030,623 		JBrowse link
G NDRG1 N-myc downstream regulated 1 multiple interactions EXP NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] CTD PMID:24532803 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions		 EXP bafilomycin A1 results in increased expression of NFE2L2 protein
bafilomycin A1 promotes the reaction [[Particulate Matter co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [[Silicon Dioxide co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Silicon Dioxide results in increased expression of NFE2L2 protein]		 CTD PMID:30698894 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions
increases expression		 EXP bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein]
bafilomycin A1 results in increased expression of NLRP3 protein		 CTD PMID:32645460 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 decreases expression EXP bafilomycin A1 results in decreased expression of NR5A1 protein CTD PMID:29524503 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression		 EXP
ISO		 [Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]
bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]
bafilomycin A1 results in increased expression of PARP1 protein modified form		 CTD PMID:20876807 PMID:21616090 PMID:24321340 PMID:25981168 PMID:28063998 More... NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions EXP bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of PCNA mRNA] CTD PMID:33359579 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of PRKAA1 protein] CTD PMID:37481222 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions EXP bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of PRKAA2 protein] CTD PMID:37481222 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRKD2 protein kinase D2 multiple interactions EXP [PRKD2 protein affects the susceptibility to [erastin co-treated with bafilomycin A1]] which affects the abundance of Malondialdehyde; bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTH1 protein]; bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTL protein]; bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of NCOA4 protein]; PRKD2 protein affects the susceptibility to [erastin co-treated with bafilomycin A1] CTD PMID:37951334 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO bafilomycin A1 affects the localization of and results in increased activity of RELA protein CTD PMID:10339586 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation		 ISO bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein		 CTD PMID:22689575 PMID:31310755 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]] CTD PMID:24889822 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC17A7 solute carrier family 17 member 7 multiple interactions ISO bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents]; bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Zinc]; bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr19:49,429,401...49,441,527
Ensembl chr19:49,429,401...49,442,360 		JBrowse link
G SLC30A3 solute carrier family 30 member 3 multiple interactions ISO bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 2:27,253,684...27,275,817
Ensembl chr 2:27,253,684...27,275,817 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLCO1B1 protein results in increased import of estradiol-17 beta-glucuronide] CTD PMID:26750564 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 multiple interactions
increases expression		 EXP bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein]
bafilomycin A1 results in increased expression of SNAI1 protein		 CTD PMID:32645460 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SNCA synuclein alpha multiple interactions
increases expression		 ISO [bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein
bafilomycin A1 results in increased expression of SNCA protein		 CTD PMID:26031332 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SORT1 sortilin 1 decreases expression ISO bafilomycin A1 results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 1:109,309,575...109,397,918
Ensembl chr 1:109,309,568...109,397,918 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
increases expression		 ISO
EXP		 [bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein; [bafilomycin A1 co-treated with Swainsonine] results in increased expression of SQSTM1 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of SQSTM1 protein; bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; decamethrin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]
[Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [metarrestin results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [Miconazole results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]]; Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]		 CTD PMID:21778691 PMID:21858812 PMID:23151917 PMID:24145604 PMID:24238063 More... NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STK11 serine/threonine kinase 11 multiple interactions EXP bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of STK11 protein] CTD PMID:37481222 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TBK1 TANK binding kinase 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TLR8 toll like receptor 8 multiple interactions EXP bafilomycin A1 inhibits the reaction [resiquimod results in increased activity of TLR8 protein] CTD PMID:21398612 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions		 ISO
EXP		 bafilomycin A1 results in increased expression of TNF mRNA
[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]		 CTD PMID:16932910 PMID:24145604 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TOMM20 translocase of outer mitochondrial membrane 20 increases expression
multiple interactions		 ISO bafilomycin A1 results in increased expression of TOMM20 protein
Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein]		 CTD PMID:30209975 NCBI chr 1:235,109,341...235,128,837
Ensembl chr 1:235,109,341...235,128,837 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein] CTD PMID:23380477 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 multiple interactions ISO bafilomycin A1 affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide affects the reaction [Glucose affects the phosphorylation of ULK1 protein]] CTD PMID:29128638 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
G USP8 ubiquitin specific peptidase 8 multiple interactions EXP [Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased cleavage of PARP1 protein] CTD PMID:35022897 NCBI chr15:50,424,405...50,514,421
Ensembl chr15:50,424,380...50,514,421 		JBrowse link
G VDAC1 voltage dependent anion channel 1 multiple interactions
increases expression		 ISO Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] CTD PMID:30209975 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G VDR vitamin D receptor multiple interactions EXP [bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein CTD PMID:30698894 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VIM vimentin multiple interactions
increases expression		 EXP bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein]
bafilomycin A1 results in increased expression of VIM protein		 CTD PMID:32645460 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
brefeldin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions ISO Brefeldin A inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] CTD PMID:15525798 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO Brefeldin A inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein]
Brefeldin A results in decreased phosphorylation of AKT1 protein		 CTD PMID:15525798 PMID:24090963 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ATF4 activating transcription factor 4 increases expression EXP Brefeldin A results in increased expression of ATF4 protein CTD PMID:24865413 PMID:27358234 PMID:32397857 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATF6 activating transcription factor 6 multiple interactions ISO Apigenin inhibits the reaction [Brefeldin A results in increased cleavage of ATF6 protein] CTD PMID:20493918 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATP7A ATPase copper transporting alpha multiple interactions EXP Brefeldin A inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G ATP7B ATPase copper transporting beta multiple interactions EXP Brefeldin A inhibits the reaction [Copper affects the localization of ATP7B protein] CTD PMID:10982773 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) increases activity
multiple interactions		 ISO Brefeldin A results in increased activity of CASP12 protein
Apigenin inhibits the reaction [Brefeldin A results in increased activity of CASP12 protein]		 CTD PMID:20493918 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP2 caspase 2 multiple interactions EXP Bortezomib promotes the reaction [Brefeldin A results in increased cleavage of and results in increased activity of CASP2 protein]; Brefeldin A promotes the reaction [Bortezomib results in increased cleavage of and results in increased activity of CASP2 protein]; Brefeldin A results in increased cleavage of and results in increased activity of CASP2 protein CTD PMID:18723477 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions		 ISO
EXP		 Brefeldin A results in increased activity of CASP3 protein
Apigenin inhibits the reaction [Brefeldin A results in increased activity of CASP3 protein]		 CTD PMID:20150630 PMID:20493918 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CFTR CF transmembrane conductance regulator decreases activity
multiple interactions		 EXP Brefeldin A results in decreased activity of CFTR protein
Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat results in increased activity of CFTR protein mutant form]		 CTD PMID:15371258 PMID:18230692 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions EXP Brefeldin A inhibits the reaction [kaempferol results in increased secretion of CSF2 protein]; Brefeldin A inhibits the reaction [Quercetin results in increased secretion of CSF2 protein] CTD PMID:18346843 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 multiple interactions EXP Brefeldin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] CTD PMID:22167199 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions		 EXP
ISO		 Brefeldin A results in increased expression of DDIT3 mRNA; Brefeldin A results in increased expression of DDIT3 protein
Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of DDIT3 protein]; Apigenin inhibits the reaction [Brefeldin A results in increased expression of DDIT3 protein]; Glutathione inhibits the reaction [Brefeldin A results in increased expression of DDIT3 protein]		 CTD PMID:19428936 PMID:20493918 PMID:20626587 PMID:24865413 PMID:27358234 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression EXP Brefeldin A results in increased expression of EIF2AK3 protein CTD PMID:24865413 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases phosphorylation		 ISO Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein] CTD PMID:20493918 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G FHL1 four and a half LIM domains 1 multiple interactions ISO Brefeldin A inhibits the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA] CTD PMID:17161435 NCBI chr  X:136,146,702...136,211,359
Ensembl chr  X:136,146,702...136,211,359 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions
increases expression		 ISO Apigenin inhibits the reaction [Brefeldin A results in increased expression of HSP90B1 protein] CTD PMID:20493918 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; Apigenin inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; Glutathione inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]
Brefeldin A results in increased expression of HSPA5 mRNA; Brefeldin A results in increased expression of HSPA5 protein
Bortezomib inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; Brefeldin A inhibits the reaction [Shiga toxin subunit A results in increased cleavage of HSPA5 protein]		 CTD PMID:12147617 PMID:18723477 PMID:19428936 PMID:20493918 PMID:20626587 More... NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G IL6 interleukin 6 decreases secretion
multiple interactions		 ISO
EXP		 Brefeldin A results in decreased secretion of IL6 protein
Brefeldin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]		 CTD PMID:11216681 PMID:22102721 PMID:24849676 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases expression		 EXP Brefeldin A promotes the reaction [vandetanib results in decreased expression of KCNH2 protein modified form]
Brefeldin A results in decreased expression of KCNH2 protein modified form		 CTD PMID:35680041 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions EXP [aloxistatin co-treated with pepstatin] promotes the reaction [Brefeldin A results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Brefeldin A results in increased expression of and results in increased lipidation of MAP1LC3B protein CTD PMID:32397857 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation
multiple interactions		 ISO Brefeldin A results in decreased phosphorylation of MAPK1 protein
Brefeldin A inhibits the reaction [Levodopa results in increased phosphorylation of MAPK1 protein]		 CTD PMID:24090963 PMID:25044243 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation
multiple interactions		 ISO Brefeldin A results in decreased phosphorylation of MAPK3 protein
Brefeldin A inhibits the reaction [Levodopa results in increased phosphorylation of MAPK3 protein]		 CTD PMID:24090963 PMID:25044243 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 multiple interactions EXP Brefeldin A affects the reaction [sodium arsenite affects the localization of NFE2L1 protein] CTD PMID:20805060 NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Brefeldin A inhibits the reaction [sodium arsenite results in increased activity of NFE2L2 protein] CTD PMID:20805060 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 decreases expression EXP Brefeldin A results in decreased expression of NR1I2 mRNA CTD PMID:25616597 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO Apigenin inhibits the reaction [Brefeldin A results in increased cleavage of PARP1 protein] CTD PMID:20493918 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta multiple interactions ISO Brefeldin A inhibits the reaction [Terbutaline inhibits the reaction [Oxygen deficiency results in decreased expression of SCNN1B protein]] CTD PMID:12608646 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma multiple interactions ISO Brefeldin A inhibits the reaction [Terbutaline inhibits the reaction [Oxygen deficiency results in decreased expression of SCNN1G protein]] CTD PMID:12608646 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883 		JBrowse link
G TNF tumor necrosis factor decreases secretion ISO Brefeldin A results in decreased secretion of TNF protein CTD PMID:22102721 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a multiple interactions EXP Brefeldin A inhibits the reaction [Bortezomib results in increased localization of TNFRSF10A protein] CTD PMID:17326159 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b multiple interactions EXP Brefeldin A inhibits the reaction [Bortezomib results in increased localization of TNFRSF10B protein] CTD PMID:17326159 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFSF10 TNF superfamily member 10 multiple interactions EXP Brefeldin A affects the reaction [Bortezomib results in increased susceptibility to and results in increased activity of TNFSF10 protein] CTD PMID:17326159 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 increases expression EXP Brefeldin A results in increased expression of TP53BP1 protein CTD PMID:27358234 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases secretion
multiple interactions
increases expression		 EXP
ISO		 Brefeldin A results in decreased secretion of VEGFA protein
Brefeldin A inhibits the reaction [cobaltous chloride results in increased secretion of VEGFA protein]
Brefeldin A results in increased expression of VEGFA mRNA		 CTD PMID:12147617 PMID:20850416 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G XBP1 X-box binding protein 1 multiple interactions
increases expression
increases activity		 EXP bortezomib inhibits the reaction [Brefeldin A results in increased activity of XBP1 protein]
Brefeldin A results in increased expression of XBP1 protein		 CTD PMID:18723477 PMID:27358234 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
clarithromycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity		 EXP Clarithromycin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Clarithromycin results in decreased activity of ABCB11 protein		 CTD PMID:24014644 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 increases expression EXP Clarithromycin results in increased expression of ASAH1 mRNA CTD PMID:15342952 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G CEPT1 choline/ethanolamine phosphotransferase 1 decreases expression ISO Clarithromycin results in decreased expression of CEPT1 mRNA CTD PMID:34458952 NCBI chr 1:111,139,499...111,185,104
Ensembl chr 1:111,139,479...111,185,104 		JBrowse link
G CH25H cholesterol 25-hydroxylase increases expression ISO Clarithromycin results in increased expression of CH25H mRNA CTD PMID:34458952 NCBI chr10:89,205,629...89,207,317
Ensembl chr10:89,205,629...89,207,317 		JBrowse link
G CHPT1 choline phosphotransferase 1 decreases expression ISO Clarithromycin results in decreased expression of CHPT1 mRNA CTD PMID:34458952 NCBI chr12:101,697,640...101,729,074
Ensembl chr12:101,696,947...101,744,140 		JBrowse link
G CKM creatine kinase, M-type multiple interactions EXP [Clarithromycin co-treated with Simvastatin] results in increased expression of CKM protein CTD PMID:19252767 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Clarithromycin results in increased expression of CXCL8 protein CTD PMID:11390425 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions EXP [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline] CTD PMID:11408986 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
decreases activity
decreases expression		 EXP [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP3A4 protein results in increased metabolism of Theophylline]; Clarithromycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Clarithromycin inhibits the reaction [CYP3A4 protein results in increased metabolism of Disopyramide]
Clarithromycin results in decreased activity of CYP3A4 protein
Clarithromycin results in decreased expression of CYP3A4 mRNA		 CTD PMID:10234723 PMID:11408986 PMID:16416302 PMID:16837568 PMID:23748747 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Clarithromycin results in increased expression of FOS mRNA; Clarithromycin results in increased expression of FOS protein CTD PMID:32454074 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G IFNG interferon gamma multiple interactions ISO
EXP		 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin CTD PMID:19362101 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP
ISO		 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin CTD PMID:19362101 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL4 interleukin 4 decreases expression EXP Clarithromycin results in decreased expression of IL4 protein CTD PMID:16006447 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression		 EXP
ISO		 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin
Clarithromycin results in decreased expression of IL6 mRNA		 CTD PMID:9869567 PMID:19362101 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBE inhibin subunit beta E increases expression EXP Clarithromycin results in increased expression of INHBE mRNA CTD PMID:15342952 NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280 		JBrowse link
G ITGB4 integrin subunit beta 4 decreases expression EXP Clarithromycin results in decreased expression of ITGB4 protein CTD PMID:14687228 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 multiple interactions EXP [KCNE2 protein mutant form binds to KCNH2 protein] which results in increased susceptibility to Clarithromycin CTD PMID:10219239 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 EXP [KCNE2 protein mutant form binds to KCNH2 protein] which results in increased susceptibility to Clarithromycin
Clarithromycin results in decreased activity of KCNH2 protein		 CTD PMID:10219239 PMID:24052561 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G LSS lanosterol synthase decreases expression EXP Clarithromycin results in decreased expression of LSS mRNA CTD PMID:15342952 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression ISO Clarithromycin results in decreased expression of MMP9 mRNA CTD PMID:9869567 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP Clarithromycin results in decreased expression of COX2 protein CTD PMID:31915244 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269 		JBrowse link
G MTIF2 mitochondrial translational initiation factor 2 decreases response to substance EXP MTIF2 protein results in decreased susceptibility to Clarithromycin CTD PMID:31915244 NCBI chr 2:55,236,595...55,269,248
Ensembl chr 2:55,236,595...55,269,347 		JBrowse link
G PHYH phytanoyl-CoA 2-hydroxylase decreases expression EXP Clarithromycin results in decreased expression of PHYH mRNA CTD PMID:15342952 NCBI chr10:13,277,799...13,300,064
Ensembl chr10:13,277,796...13,302,412 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 multiple interactions EXP Clarithromycin inhibits the reaction [SLCO1B1 protein results in increased uptake of Sulfobromophthalein] CTD PMID:21430235 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP Clarithromycin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein] CTD PMID:21430235 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SV2A synaptic vesicle glycoprotein 2A decreases expression ISO Clarithromycin results in decreased expression of SV2A mRNA CTD PMID:34458952 NCBI chr 1:149,903,318...149,917,844
Ensembl chr 1:149,903,318...149,917,844 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression		 EXP
ISO		 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin
Clarithromycin results in decreased expression of TNF mRNA		 CTD PMID:9869567 PMID:19362101 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
concanamycin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO concanamycin A inhibits the reaction [enterotoxin C, staphylococcal results in increased expression of BAX protein] CTD PMID:27742270 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression
multiple interactions		 EXP concanamycin A results in increased expression of BNIP3 mRNA
lapatinib inhibits the reaction [concanamycin A results in increased expression of BNIP3 mRNA]		 CTD PMID:25981168 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO concanamycin A inhibits the reaction [enterotoxin C, staphylococcal analog results in increased activity of CASP3 protein]; concanamycin A inhibits the reaction [enterotoxin C, staphylococcal results in increased activity of CASP3 protein] CTD PMID:27742270 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 multiple interactions ISO concanamycin A inhibits the reaction [enterotoxin C, staphylococcal analog results in increased activity of CASP9 protein]; concanamycin A inhibits the reaction [enterotoxin C, staphylococcal results in increased activity of CASP9 protein] CTD PMID:27742270 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP concanamycin A results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 EXP concanamycin A results in increased expression of HIF1A protein
lapatinib inhibits the reaction [concanamycin A results in increased expression of HIF1A protein]		 CTD PMID:25981168 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP [lapatinib co-treated with concanamycin A] results in increased cleavage of PARP1 protein CTD PMID:25981168 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
emamectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 decreases activity
multiple interactions		 EXP
ISO		 emamectin results in decreased activity of ABCB1 protein
emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
emamectin results in decreased activity of ABCB1A protein
emamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]		 CTD PMID:25865432 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) multiple interactions
decreases activity		 EXP
ISO		 emamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
emamectin results in decreased activity of ABCC1 protein		 CTD PMID:25865432 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 multiple interactions EXP emamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions EXP emamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]; emamectin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; emamectin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 PMID:27773686 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
emamectin benzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions
decreases activity		 ISO Plant Oils inhibits the reaction [emamectin benzoate results in decreased activity of CAT protein] CTD PMID:29268245 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 increases expression EXP emamectin benzoate results in increased expression of CCL11 mRNA CTD PMID:36269090 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL27 C-C motif chemokine ligand 27 increases expression EXP emamectin benzoate results in increased expression of CCL27 mRNA CTD PMID:36269090 NCBI chr 9:34,661,890...34,662,657
Ensembl chr 9:34,661,880...34,664,048 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP emamectin benzoate results in increased expression of CXCL8 mRNA CTD PMID:36269090 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases expression
multiple interactions		 ISO emamectin benzoate results in increased expression of CYP2E1 mRNA
Plant Oils inhibits the reaction [emamectin benzoate results in increased expression of CYP2E1 mRNA]		 CTD PMID:29268245 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DIO1 iodothyronine deiodinase 1 decreases activity EXP emamectin benzoate results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in decreased expression of ESR1 mRNA; [cypermethrin co-treated with emamectin benzoate] results in decreased expression of ESR1 protein CTD PMID:37984602 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in increased expression of FSHB protein CTD PMID:37984602 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GNRH1 gonadotropin releasing hormone 1 multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in decreased expression of GNRH1 protein CTD PMID:37984602 NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in decreased activity of GPX1 protein CTD PMID:37984602 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP emamectin benzoate results in increased expression of and affects the localization of IKBKB protein CTD PMID:36269090 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 decreases expression EXP emamectin benzoate results in decreased expression of IL10 mRNA CTD PMID:36269090 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 decreases expression EXP emamectin benzoate results in decreased expression of IL13 mRNA CTD PMID:36269090 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL1B interleukin 1 beta increases expression EXP emamectin benzoate results in increased expression of IL1B mRNA CTD PMID:36269090 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 increases expression EXP emamectin benzoate results in increased expression of IL2 mRNA CTD PMID:36269090 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL3 interleukin 3 increases expression EXP emamectin benzoate results in increased expression of IL3 mRNA CTD PMID:36269090 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL4 interleukin 4 decreases expression EXP emamectin benzoate results in decreased expression of IL4 mRNA CTD PMID:36269090 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 increases expression EXP emamectin benzoate results in increased expression of IL5 mRNA CTD PMID:36269090 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 increases expression EXP emamectin benzoate results in increased expression of IL6 mRNA CTD PMID:36269090 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7 interleukin 7 increases expression EXP emamectin benzoate results in increased expression of IL7 mRNA CTD PMID:36269090 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
G IL9 interleukin 9 increases expression EXP emamectin benzoate results in increased expression of IL9 mRNA CTD PMID:36269090 NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in increased expression of KISS1 mRNA; [cypermethrin co-treated with emamectin benzoate] results in increased expression of KISS1 protein CTD PMID:37984602 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491 		JBrowse link
G KISS1R KISS1 receptor multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in increased expression of KISS1R mRNA; [cypermethrin co-treated with emamectin benzoate] results in increased expression of KISS1R protein CTD PMID:37984602 NCBI chr19:917,333...921,005
Ensembl chr19:917,287...921,005 		JBrowse link
G MGST1 microsomal glutathione S-transferase 1 multiple interactions
increases expression		 ISO Plant Oils inhibits the reaction [emamectin benzoate results in increased expression of MGST1 mRNA] CTD PMID:29268245 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259 		JBrowse link
G MIF macrophage migration inhibitory factor increases expression EXP emamectin benzoate results in increased expression of MIF mRNA CTD PMID:36269090 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases expression EXP emamectin benzoate results in increased expression of NFKBIA protein CTD PMID:36269090 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression EXP emamectin benzoate results in decreased expression of NOS2 protein CTD PMID:36269090 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NTS neurotensin affects activity EXP emamectin benzoate affects the activity of NTS protein CTD PMID:23611293 NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases phosphorylation EXP emamectin benzoate results in increased phosphorylation of RELA protein CTD PMID:36269090 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO [cypermethrin co-treated with emamectin benzoate] results in decreased activity of SOD1 protein CTD PMID:37984602 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G TNF tumor necrosis factor increases expression EXP emamectin benzoate results in increased expression of TNF mRNA CTD PMID:36269090 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
erythromycin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
affects transport		 EXP
ISO		 Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]
ABCB1 protein affects the transport of Erythromycin		 CTD PMID:12235267 PMID:15304119 PMID:25268938 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity		 EXP Erythromycin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Erythromycin results in decreased activity of ABCB11 protein		 CTD PMID:24014644 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha multiple interactions
increases expression		 ISO [Penicillin G co-treated with Erythromycin] results in increased expression of ACACA mRNA
Erythromycin results in increased expression of ACACA mRNA		 CTD PMID:27503388 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACLY ATP citrate lyase increases expression
multiple interactions		 ISO Erythromycin results in increased expression of ACLY mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of ACLY mRNA		 CTD PMID:27503388 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 increases expression EXP Erythromycin results in increased expression of ASAH1 mRNA CTD PMID:17175557 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) decreases expression EXP Erythromycin results in decreased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions		 EXP Erythromycin results in increased activity of CASP3 protein
[Erythromycin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Erythromycin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Erythromycin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] inhibits the reaction [Erythromycin results in increased activity of CASP3 protein]		 CTD PMID:30876886 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions EXP [Benzoyl Peroxide co-treated with Erythromycin] results in decreased activity of CAT protein CTD PMID:11809596 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression
multiple interactions		 ISO Erythromycin results in increased expression of CCL2 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of CCL2 mRNA		 CTD PMID:27503388 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases expression
multiple interactions		 ISO Erythromycin results in increased expression of CCR2 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of CCR2 mRNA		 CTD PMID:27503388 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CD34 CD34 molecule increases expression EXP Erythromycin results in increased expression of CD34 protein CTD PMID:16297520 NCBI chr 1:207,880,972...207,911,125
Ensembl chr 1:207,880,972...207,911,402 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) increases expression
multiple interactions		 ISO Erythromycin results in increased expression of CD36 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of CD36 mRNA		 CTD PMID:27503388 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions
increases expression		 ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CPT1A mRNA
Erythromycin results in increased expression of CPT1A mRNA		 CTD PMID:27503388 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CRP C-reactive protein increases expression
multiple interactions		 ISO Erythromycin results in increased expression of CRP mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of CRP mRNA		 CTD PMID:27503388 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CS citrate synthase increases expression
multiple interactions		 ISO Erythromycin results in increased expression of CS mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of CS mRNA		 CTD PMID:27503388 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Erythromycin inhibits the reaction [Particulate Matter results in increased expression of CXCL8 mRNA] CTD PMID:23291319 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression ISO Erythromycin results in increased expression of CXCR4 protein CTD PMID:19502290 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 increases expression EXP Erythromycin results in increased expression of CYP11B2 CTD PMID:17822730 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 decreases activity ISO Erythromycin results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 decreases activity ISO Erythromycin results in decreased activity of CYP2C9 protein CTD PMID:18420780 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 decreases activity ISO Erythromycin results in decreased activity of CYP2D22 protein CTD PMID:18420780 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 affects metabolic processing
increases expression
decreases activity
increases metabolic processing
multiple interactions
decreases methylation		 EXP CYP3A4 protein affects the metabolism of Erythromycin
Erythromycin results in increased expression of CYP3A4 mRNA; Erythromycin results in increased expression of CYP3A4 protein
Erythromycin results in decreased activity of CYP3A4 protein
CYP3A4 protein results in increased metabolism of Erythromycin
Erythromycin inhibits the reaction [CYP3A4 protein affects the metabolism of brotizolam]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Erythromycin inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; IFNA protein inhibits the reaction [CYP3A4 protein results in increased metabolism of Erythromycin]
CYP3A4 protein results in decreased methylation of Erythromycin		 CTD PMID:2271712 PMID:8114683 PMID:15383492 PMID:15466163 PMID:15845683 More... NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 decreases methylation EXP CYP3A5 protein results in decreased methylation of Erythromycin CTD PMID:15383492 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G DEFB1 defensin beta 1 decreases expression
multiple interactions		 ISO Erythromycin results in decreased expression of DEFB1 mRNA
[Penicillin G co-treated with Erythromycin] results in decreased expression of DEFB1 mRNA		 CTD PMID:27503388 NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936 		JBrowse link
G DEPP1 DEPP autophagy regulator 1 increases expression EXP Erythromycin results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of DGAT1 mRNA CTD PMID:27503388 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of DGAT2 mRNA CTD PMID:27503388 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G FABP1 fatty acid binding protein 1 increases expression
multiple interactions		 EXP
ISO		 Erythromycin results in increased expression of FABP1 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of FABP1 mRNA		 CTD PMID:17175557 PMID:27503388 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062 		JBrowse link
G FASN fatty acid synthase increases expression
multiple interactions		 ISO Erythromycin results in increased expression of FASN mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of FASN mRNA		 CTD PMID:27503388 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FNDC4 fibronectin type III domain containing 4 decreases expression EXP Erythromycin results in decreased expression of FNDC4 mRNA CTD PMID:17175557 NCBI chr 2:27,491,883...27,495,200
Ensembl chr 2:27,491,883...27,495,200 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Erythromycin results in increased expression of FOS mRNA; Erythromycin results in increased expression of FOS protein CTD PMID:32454074 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial increases expression
multiple interactions		 ISO Erythromycin results in increased expression of GPAM mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of GPAM mRNA		 CTD PMID:27503388 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377 		JBrowse link
G HLA-A major histocompatibility complex, class I, A affects expression EXP Erythromycin affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-B major histocompatibility complex, class I, B affects expression EXP Erythromycin affects the expression of HLA-B mRNA CTD PMID:25811541 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-G major histocompatibility complex, class I, G affects expression EXP Erythromycin affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP Erythromycin inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]; Erythromycin inhibits the reaction [Vehicle Emissions results in increased expression of HMOX1 mRNA] CTD PMID:23291319 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HPN hepsin increases expression EXP Erythromycin results in increased expression of HPN mRNA CTD PMID:17175557 NCBI chr19:35,040,506...35,066,573
Ensembl chr19:35,040,506...35,066,573 		JBrowse link
G HRH1 histamine receptor H1 multiple interactions ISO [Diphenhydramine results in decreased activity of HRH1 protein] which results in decreased susceptibility to Erythromycin CTD PMID:12856827 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Erythromycin results in increased expression of ICAM1 protein CTD PMID:14729754 PMID:16297520 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNG interferon gamma multiple interactions
increases expression		 ISO [Penicillin G co-treated with Erythromycin] results in increased expression of IFNG mRNA
Erythromycin results in increased expression of IFNG mRNA		 CTD PMID:27503388 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions		 ISO Erythromycin results in increased expression of IL1A mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA		 CTD PMID:27503388 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP [Erythromycin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] inhibits the reaction [Erythromycin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 ISO
EXP		 Erythromycin results in increased expression of IL6 mRNA
[Erythromycin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] inhibits the reaction [Erythromycin results in increased activity of CASP3 protein]
[Penicillin G co-treated with Erythromycin] results in increased expression of IL6 mRNA		 CTD PMID:27503388 PMID:30876886 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBE inhibin subunit beta E increases expression EXP Erythromycin results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 affects binding
decreases activity
multiple interactions		 EXP Erythromycin binds to KCNH2 protein
Erythromycin results in decreased activity of KCNH2 protein
Erythromycin affects the reaction [KCNH2 protein results in decreased susceptibility to Doxorubicin]; Erythromycin binds to and results in decreased activity of KCNH2 protein		 CTD PMID:15272206 PMID:16086867 PMID:18701618 PMID:24052561 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G LBP lipopolysaccharide binding protein multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of LBP mRNA CTD PMID:27503388 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LSS lanosterol synthase increases expression EXP Erythromycin results in increased expression of LSS mRNA CTD PMID:17175557 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G MLNR motilin receptor multiple interactions EXP Erythromycin binds to and results in increased activity of MLNR protein CTD PMID:19374732 NCBI chr13:49,220,338...49,222,377
Ensembl chr13:49,220,338...49,222,377 		JBrowse link
G MTTP microsomal triglyceride transfer protein multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of MTTP mRNA CTD PMID:27503388 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming decreases expression
multiple interactions		 ISO Erythromycin results in decreased expression of MUC2 mRNA
[Penicillin G co-treated with Erythromycin] results in decreased expression of MUC2 mRNA		 CTD PMID:27503388 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Erythromycin inhibits the reaction [Particulate Matter results in increased activity of NFE2L2 protein]; Erythromycin inhibits the reaction [Vehicle Emissions results in increased activity of NFE2L2 protein] CTD PMID:23291319 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases expression
multiple interactions		 ISO Erythromycin results in increased expression of NFKB1 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of NFKB1 mRNA		 CTD PMID:27503388 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP Erythromycin inhibits the reaction [Particulate Matter results in increased expression of NQO1 mRNA]; Erythromycin inhibits the reaction [Vehicle Emissions results in increased expression of NQO1 mRNA] CTD PMID:23291319 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator increases expression
decreases expression		 EXP Erythromycin results in increased expression of NUPR1 mRNA
Erythromycin results in decreased expression of NUPR1 mRNA		 CTD PMID:17175557 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G PLA2G2A phospholipase A2 group IIA decreases expression ISO Erythromycin results in decreased expression of PLA2G2A mRNA CTD PMID:27503388 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G REG3G regenerating family member 3 gamma multiple interactions
decreases expression		 ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of REG3G mRNA
Erythromycin results in decreased expression of REG3G mRNA		 CTD PMID:27503388 NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505 		JBrowse link
G RETNLB resistin like beta multiple interactions
decreases expression		 ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of RETNLB mRNA
Erythromycin results in decreased expression of RETNLB mRNA		 CTD PMID:27503388 NCBI chr 3:108,755,638...108,757,410
Ensembl chr 3:108,743,424...108,757,410 		JBrowse link
G SELE selectin E increases expression EXP Erythromycin results in increased expression of SELE protein CTD PMID:16297520 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SELL selectin L increases expression EXP Erythromycin results in increased expression of SELL protein CTD PMID:16297520 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 multiple interactions EXP
ISO		 Erythromycin inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]
Erythromycin inhibits the reaction [SLC22A7 protein results in increased uptake of Glutarates]		 CTD PMID:12065749 PMID:15901346 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC27A2 solute carrier family 27 member 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SLC27A2 mRNA CTD PMID:27503388 NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions		 ISO Erythromycin results in increased expression of SREBF1 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA		 CTD PMID:27503388 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G TAGLN transgelin decreases expression EXP Erythromycin results in decreased expression of TAGLN mRNA CTD PMID:17567588 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TLR4 toll like receptor 4 increases expression
multiple interactions		 ISO Erythromycin results in increased expression of TLR4 mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA		 CTD PMID:27503388 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions		 ISO
EXP		 Erythromycin results in increased expression of TNF mRNA
[Erythromycin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] inhibits the reaction [Erythromycin results in increased activity of CASP3 protein]
[Penicillin G co-treated with Erythromycin] results in increased expression of TNF mRNA		 CTD PMID:27503388 PMID:30876886 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression EXP Erythromycin results in increased expression of VCAM1 protein CTD PMID:16297520 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G WIPI1 WD repeat domain, phosphoinositide interacting 1 increases expression EXP Erythromycin results in increased expression of WIPI1 mRNA CTD PMID:17175557 NCBI chr17:68,421,281...68,457,496
Ensembl chr17:68,420,948...68,457,513 		JBrowse link
erythromycin estolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression ISO Erythromycin Estolate results in increased expression of ABCB1 mRNA; Erythromycin Estolate results in increased expression of ABCB1A mRNA CTD PMID:17522070 PMID:24412560 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 decreases expression
decreases activity		 ISO
EXP		 Erythromycin Estolate results in decreased expression of ABCB11 mRNA
Erythromycin Estolate results in decreased activity of ABCB11 protein		 CTD PMID:17522070 PMID:20829430 PMID:23956101 PMID:28437613 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 increases expression ISO Erythromycin Estolate results in increased expression of ABCC3 mRNA CTD PMID:17522070 PMID:24412560 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 increases expression ISO Erythromycin Estolate results in increased expression of ABCG5 mRNA CTD PMID:24412560 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 increases expression ISO Erythromycin Estolate results in increased expression of ABCG8 mRNA CTD PMID:24412560 NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain decreases expression ISO Erythromycin Estolate results in decreased expression of ACADM mRNA CTD PMID:17522070 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACLY ATP citrate lyase decreases expression ISO Erythromycin Estolate results in decreased expression of ACLY mRNA CTD PMID:17522070 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 decreases expression ISO Erythromycin Estolate results in decreased expression of ACSL1 mRNA CTD PMID:17522070 NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases expression ISO Erythromycin Estolate results in increased expression of ALDH1A1 mRNA CTD PMID:24412560 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 decreases expression ISO Erythromycin Estolate results in decreased expression of ALDH3A2 mRNA CTD PMID:17522070 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression ISO Erythromycin Estolate results in decreased expression of APEX1 mRNA CTD PMID:17522070 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G ASPM assembly factor for spindle microtubules decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of ASPM mRNA
Erythromycin Estolate results in increased expression of ASPM mRNA		 CTD PMID:24412560 NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,121...197,146,694 		JBrowse link
G AURKB aurora kinase B increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of AURKB mRNA
Erythromycin Estolate results in decreased expression of AURKB mRNA		 CTD PMID:24412560 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression ISO Erythromycin Estolate results in decreased expression of BAX mRNA CTD PMID:12883083 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression ISO Erythromycin Estolate results in increased expression of BCL2 mRNA CTD PMID:12883083 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression ISO Erythromycin Estolate results in increased expression of BTG2 mRNA CTD PMID:17522070 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G CA1 carbonic anhydrase 1 decreases expression ISO Erythromycin Estolate results in decreased expression of CAR1 mRNA CTD PMID:24412560 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I decreases expression ISO Erythromycin Estolate results in decreased expression of CACNA1I mRNA CTD PMID:24412560 NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735 		JBrowse link
G CALU calumenin increases expression ISO Erythromycin Estolate results in increased expression of CALU mRNA CTD PMID:17522070 NCBI chr 7:128,739,359...128,773,400
Ensembl chr 7:128,739,292...128,773,400 		JBrowse link
G CAT catalase decreases expression ISO Erythromycin Estolate results in decreased expression of CAT mRNA CTD PMID:17522070 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCN2 cellular communication network factor 2 decreases expression ISO Erythromycin Estolate results in decreased expression of CCN2 mRNA CTD PMID:24412560 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNA2 cyclin A2 increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of CCNA2 mRNA
Erythromycin Estolate results in decreased expression of CCNA2 mRNA		 CTD PMID:24412560 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of CCNB1 mRNA
Erythromycin Estolate results in increased expression of CCNB1 mRNA		 CTD PMID:24412560 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CDCA3 cell division cycle associated 3 decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of CDCA3 mRNA
Erythromycin Estolate results in increased expression of CDCA3 mRNA		 CTD PMID:24412560 NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292 		JBrowse link
G CDK1 cyclin dependent kinase 1 increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of CDK1 mRNA
Erythromycin Estolate results in decreased expression of CDK1 mRNA		 CTD PMID:24412560 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 decreases expression ISO Erythromycin Estolate results in decreased expression of CEACAM1 mRNA CTD PMID:17522070 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G CENPW centromere protein W increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of CENPW mRNA
Erythromycin Estolate results in decreased expression of CENPW mRNA		 CTD PMID:24412560 NCBI chr 6:126,340,115...126,483,320
Ensembl chr 6:126,340,115...126,348,875 		JBrowse link
G CES2 carboxylesterase 2 increases expression ISO Erythromycin Estolate results in increased expression of CES2 mRNA CTD PMID:24412560 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096 		JBrowse link
G CHD2 chromodomain helicase DNA binding protein 2 increases expression ISO Erythromycin Estolate results in increased expression of CHD2 mRNA CTD PMID:24412560 NCBI chr15:92,900,324...93,027,996
Ensembl chr15:92,886,203...93,027,996 		JBrowse link
G CTSL cathepsin L increases expression ISO Erythromycin Estolate results in increased expression of CTSL mRNA CTD PMID:17522070 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 decreases expression ISO Erythromycin Estolate results in decreased expression of CYB5R3 mRNA CTD PMID:17522070 NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO Erythromycin Estolate results in increased expression of CYP1A1 mRNA CTD PMID:24412560 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 increases expression ISO Erythromycin Estolate results in increased expression of CYP3A9 mRNA CTD PMID:24412560 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 increases expression ISO Erythromycin Estolate results in increased expression of CYP8B1 mRNA CTD PMID:24412560 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression ISO Erythromycin Estolate results in increased expression of DDIT3 mRNA CTD PMID:17522070 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DUT deoxyuridine triphosphatase increases expression ISO Erythromycin Estolate results in increased expression of DUT mRNA CTD PMID:24412560 NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373 		JBrowse link
G ECT2 epithelial cell transforming 2 decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of ECT2 mRNA
Erythromycin Estolate results in increased expression of ECT2 mRNA		 CTD PMID:24412560 NCBI chr 3:172,750,726...172,829,265
Ensembl chr 3:172,750,682...172,821,474 		JBrowse link
G FABP1 fatty acid binding protein 1 increases expression ISO Erythromycin Estolate results in increased expression of FABP1 mRNA CTD PMID:17522070 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062 		JBrowse link
G FADS1 fatty acid desaturase 1 decreases expression ISO Erythromycin Estolate results in decreased expression of FADS1 mRNA CTD PMID:17522070 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318 		JBrowse link
G FAM111A FAM111 trypsin like peptidase A increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of FAM111A mRNA
Erythromycin Estolate results in decreased expression of FAM111A mRNA		 CTD PMID:24412560 NCBI chr11:59,142,856...59,155,039
Ensembl chr11:59,142,748...59,155,039 		JBrowse link
G FASN fatty acid synthase decreases expression ISO Erythromycin Estolate results in decreased expression of FASN mRNA CTD PMID:17522070 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FGA fibrinogen alpha chain increases expression ISO Erythromycin Estolate results in increased expression of FGA mRNA CTD PMID:17522070 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGB fibrinogen beta chain increases expression ISO Erythromycin Estolate results in increased expression of FGB mRNA CTD PMID:17522070 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Erythromycin Estolate results in decreased expression of FMO1 mRNA CTD PMID:17522070 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Erythromycin Estolate results in decreased expression of G6PC1 mRNA CTD PMID:24412560 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression ISO Erythromycin Estolate results in increased expression of GADD45A mRNA CTD PMID:17522070 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GCK glucokinase decreases expression ISO Erythromycin Estolate results in decreased expression of GCK mRNA CTD PMID:17522070 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression ISO Erythromycin Estolate results in decreased expression of GPX1 mRNA CTD PMID:17522070 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX2 glutathione peroxidase 2 increases expression ISO Erythromycin Estolate results in increased expression of GPX2 mRNA CTD PMID:24412560 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GSTM3 glutathione S-transferase mu 3 decreases expression ISO Erythromycin Estolate results in decreased expression of GSTM3 mRNA CTD PMID:17522070 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038 		JBrowse link
G HIBADH 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Erythromycin Estolate results in decreased expression of HIBADH mRNA CTD PMID:17522070 NCBI chr 7:27,525,442...27,662,883
Ensembl chr 7:27,525,442...27,662,883 		JBrowse link
G HMMR hyaluronan mediated motility receptor increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of HMMR mRNA
Erythromycin Estolate results in decreased expression of HMMR mRNA		 CTD PMID:24412560 NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941 		JBrowse link
G IGF2R insulin like growth factor 2 receptor increases expression ISO Erythromycin Estolate results in increased expression of IGF2R mRNA CTD PMID:24412560 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 increases expression ISO Erythromycin Estolate results in increased expression of IGFBP1 mRNA CTD PMID:17522070 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 increases expression ISO Erythromycin Estolate results in increased expression of IGFBP2 mRNA CTD PMID:24412560 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IP6K2 inositol hexakisphosphate kinase 2 decreases expression ISO Erythromycin Estolate results in decreased expression of IP6K2 mRNA CTD PMID:24412560 NCBI chr 3:48,688,003...48,717,221
Ensembl chr 3:48,688,003...48,740,353 		JBrowse link
G ISY1 ISY1 splicing factor homolog increases expression ISO Erythromycin Estolate results in increased expression of ISY1 mRNA CTD PMID:24412560 NCBI chr 3:129,127,415...129,161,063
Ensembl chr 3:129,127,415...129,161,063 		JBrowse link
G KIF20B kinesin family member 20B increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of KIF20B mRNA
Erythromycin Estolate results in decreased expression of KIF20B mRNA		 CTD PMID:24412560 NCBI chr10:89,701,590...89,774,934
Ensembl chr10:89,701,590...89,774,939 		JBrowse link
G KIF23 kinesin family member 23 increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of KIF23 mRNA
Erythromycin Estolate results in decreased expression of KIF23 mRNA		 CTD PMID:24412560 NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427 		JBrowse link
G KIF2C kinesin family member 2C decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of KIF2C mRNA
Erythromycin Estolate results in increased expression of KIF2C mRNA		 CTD PMID:24412560 NCBI chr 1:44,739,837...44,767,767
Ensembl chr 1:44,739,818...44,767,767 		JBrowse link
G KRT18 keratin 18 increases expression ISO Erythromycin Estolate results in increased expression of KRT18 mRNA CTD PMID:17522070 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G LBP lipopolysaccharide binding protein increases expression ISO Erythromycin Estolate results in increased expression of LBP mRNA CTD PMID:17522070 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LGALS3 galectin 3 increases expression ISO Erythromycin Estolate results in increased expression of LGALS3 mRNA CTD PMID:17522070 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LIPC lipase C, hepatic type decreases expression ISO Erythromycin Estolate results in decreased expression of LIPC mRNA CTD PMID:17522070 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPIN1 lipin 1 decreases expression ISO Erythromycin Estolate results in decreased expression of LPIN1 mRNA CTD PMID:24412560 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G LPL lipoprotein lipase increases expression ISO Erythromycin Estolate results in increased expression of LPL mRNA CTD PMID:17522070 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G MAOB monoamine oxidase B decreases expression ISO Erythromycin Estolate results in decreased expression of MAOB mRNA CTD PMID:17522070 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450 		JBrowse link
G MIR16-2 microRNA 16-2 increases expression ISO Erythromycin Estolate results in increased expression of MIR16 mRNA CTD PMID:17522070 NCBI chr 3:160,404,745...160,404,825
Ensembl chr 3:160,404,745...160,404,825 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of MYC mRNA
Erythromycin Estolate results in decreased expression of MYC mRNA		 CTD PMID:17522070 PMID:24412560 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NCAPH non-SMC condensin I complex subunit H decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of NCAPH mRNA
Erythromycin Estolate results in increased expression of NCAPH mRNA		 CTD PMID:24412560 NCBI chr 2:96,335,766...96,377,091
Ensembl chr 2:96,335,766...96,377,091 		JBrowse link
G NFKBIB NFKB inhibitor beta decreases expression ISO Erythromycin Estolate results in decreased expression of NFKBIB mRNA CTD PMID:17522070 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893 		JBrowse link
G NOCT nocturnin decreases expression ISO Erythromycin Estolate results in decreased expression of NOCT mRNA CTD PMID:24412560 NCBI chr 4:139,015,781...139,045,939
Ensembl chr 4:139,015,781...139,045,939 		JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of NUSAP1 mRNA
Erythromycin Estolate results in decreased expression of NUSAP1 mRNA		 CTD PMID:24412560 NCBI chr15:41,332,881...41,381,046
Ensembl chr15:41,320,794...41,381,050 		JBrowse link
G OTC ornithine transcarbamylase decreases expression ISO Erythromycin Estolate results in decreased expression of OTC mRNA CTD PMID:17522070 NCBI chr  X:38,327,684...38,422,928
Ensembl chr  X:38,352,586...38,421,446 		JBrowse link
G PCLAF PCNA clamp associated factor decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of PCLAF mRNA
Erythromycin Estolate results in increased expression of PCLAF mRNA		 CTD PMID:24412560 NCBI chr15:64,364,304...64,387,687
Ensembl chr15:64,364,304...64,387,687 		JBrowse link
G PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 decreases expression ISO Erythromycin Estolate results in decreased expression of PCMTD1 mRNA CTD PMID:24412560 NCBI chr 8:51,817,575...51,899,186
Ensembl chr 8:51,817,575...51,899,186 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 decreases expression ISO Erythromycin Estolate results in decreased expression of PDK4 mRNA CTD PMID:24412560 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PER1 period circadian regulator 1 decreases expression ISO Erythromycin Estolate results in decreased expression of PER1 mRNA CTD PMID:24412560 NCBI chr17:8,140,472...8,152,404
Ensembl chr17:8,140,472...8,156,506 		JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO Erythromycin Estolate results in decreased expression of PFKFB3 mRNA CTD PMID:24412560 NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644 		JBrowse link
G PKLR pyruvate kinase L/R decreases expression ISO Erythromycin Estolate results in decreased expression of PKLR mRNA CTD PMID:17522070 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438 		JBrowse link
G PYGL glycogen phosphorylase L decreases expression ISO Erythromycin Estolate results in decreased expression of PYGL mRNA CTD PMID:17522070 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483 		JBrowse link
G RAD51 RAD51 recombinase increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of RAD51 mRNA
Erythromycin Estolate results in decreased expression of RAD51 mRNA		 CTD PMID:24412560 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of RRM2 mRNA
Erythromycin Estolate results in increased expression of RRM2 mRNA		 CTD PMID:24412560 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G S100A8 S100 calcium binding protein A8 increases expression ISO Erythromycin Estolate results in increased expression of S100A8 mRNA CTD PMID:17522070 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G S100A9 S100 calcium binding protein A9 increases expression ISO Erythromycin Estolate results in increased expression of S100A9 mRNA CTD PMID:17522070 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G SERPINA7 serpin family A member 7 increases expression ISO Erythromycin Estolate results in increased expression of SERPINA7 mRNA CTD PMID:24412560 NCBI chr  X:106,032,435...106,038,727
Ensembl chr  X:106,032,435...106,038,727 		JBrowse link
G SERTAD3 SERTA domain containing 3 increases expression ISO Erythromycin Estolate results in increased expression of SERTAD3 mRNA CTD PMID:24412560 NCBI chr19:40,440,844...40,444,335
Ensembl chr19:40,440,844...40,444,335 		JBrowse link
G SHCBP1 SHC binding and spindle associated 1 decreases expression
increases expression		 ISO Erythromycin Estolate results in decreased expression of SHCBP1 mRNA
Erythromycin Estolate results in increased expression of SHCBP1 mRNA		 CTD PMID:24412560 NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 decreases expression ISO Erythromycin Estolate results in decreased expression of SLC38A2 mRNA CTD PMID:24412560 NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773 		JBrowse link
G SLCO1A2 solute carrier organic anion transporter family member 1A2 increases expression ISO Erythromycin Estolate results in increased expression of SLCO1A4 mRNA CTD PMID:24412560 NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 decreases expression ISO Erythromycin Estolate results in decreased expression of SLCO1B2 mRNA CTD PMID:17522070 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SPC25 SPC25 component of NDC80 kinetochore complex increases expression
decreases expression		 ISO Erythromycin Estolate results in increased expression of SPC25 mRNA
Erythromycin Estolate results in decreased expression of SPC25 mRNA		 CTD PMID:24412560 NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371 		JBrowse link
G SPIN2B spindlin family member 2B decreases expression ISO Erythromycin Estolate results in decreased expression of SPIN2B mRNA CTD PMID:17522070 NCBI chr  X:57,119,682...57,121,548
Ensembl chr  X:57,118,551...57,121,548 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 increases expression ISO Erythromycin Estolate results in increased expression of SPINK1 mRNA CTD PMID:24412560 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 decreases expression ISO Erythromycin Estolate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression ISO Erythromycin Estolate results in increased expression of STAT3 mRNA CTD PMID:17522070 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 increases expression ISO Erythromycin Estolate results in increased expression of STYXL1 mRNA CTD PMID:24412560 NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004 		JBrowse link
G SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone increases expression ISO Erythromycin Estolate results in increased expression of SUGT1 mRNA CTD PMID:24412560 NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909 		JBrowse link
G TGFB3 transforming growth factor beta 3 decreases expression ISO Erythromycin Estolate results in decreased expression of TGFB3 mRNA CTD PMID:24412560 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011 		JBrowse link
G THRSP thyroid hormone responsive decreases expression ISO Erythromycin Estolate results in decreased expression of THRSP mRNA CTD PMID:17522070 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression ISO Erythromycin Estolate results in increased expression of TIMP1 mRNA CTD PMID:17522070 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TMCC1 transmembrane and coiled-coil domain family 1 decreases expression ISO Erythromycin Estolate results in decreased expression of TMCC1 mRNA CTD PMID:24412560 NCBI chr 3:129,647,792...129,893,711
Ensembl chr 3:129,647,792...129,893,711 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 decreases expression ISO Erythromycin Estolate results in decreased expression of TNFAIP3 mRNA CTD PMID:24412560 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A increases expression ISO Erythromycin Estolate results in increased expression of TNFRSF1A mRNA CTD PMID:17522070 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 decreases expression ISO Erythromycin Estolate results in decreased expression of TP53 mRNA CTD PMID:17522070 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TSC22D3 TSC22 domain family member 3 decreases expression ISO Erythromycin Estolate results in decreased expression of TSC22D3 mRNA CTD PMID:24412560 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342 		JBrowse link
G TTR transthyretin decreases expression ISO Erythromycin Estolate results in decreased expression of TTR mRNA CTD PMID:17522070 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G TXNRD1 thioredoxin reductase 1 decreases expression ISO Erythromycin Estolate results in decreased expression of TXNRD1 mRNA CTD PMID:17522070 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus increases expression ISO Erythromycin Estolate results in increased expression of UGT2A1 mRNA CTD PMID:24412560 NCBI chr 4:69,588,417...69,653,247
Ensembl chr 4:69,588,417...69,653,249 		JBrowse link
G ZC3H13 zinc finger CCCH-type containing 13 increases expression ISO Erythromycin Estolate results in increased expression of ZC3H13 mRNA CTD PMID:24412560 NCBI chr13:45,954,465...46,052,746
Ensembl chr13:45,954,465...46,052,759 		JBrowse link
G ZNF354A zinc finger protein 354A decreases expression ISO Erythromycin Estolate results in decreased expression of ZFP354A mRNA CTD PMID:24412560 NCBI chr 5:178,711,512...178,730,659
Ensembl chr 5:178,711,512...178,730,659 		JBrowse link
G ZNF574 zinc finger protein 574 increases expression ISO Erythromycin Estolate results in increased expression of ZFP574 mRNA CTD PMID:24412560 NCBI chr19:42,068,477...42,081,552
Ensembl chr19:42,068,477...42,081,552 		JBrowse link
fidaxomicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC51A solute carrier family 51 member A multiple interactions EXP Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Glycochenodeoxycholic Acid]; Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Glycocholic Acid]; Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Taurochenodeoxycholic Acid]; Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Taurocholic Acid] CTD PMID:32294204 NCBI chr 3:196,216,534...196,233,427
Ensembl chr 3:196,211,487...196,243,178 		JBrowse link
G SLC51B SLC51 subunit beta multiple interactions EXP Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Glycochenodeoxycholic Acid]; Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Glycocholic Acid]; Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Taurochenodeoxycholic Acid]; Fidaxomicin inhibits the reaction [[SLC51A protein binds to SLC51B protein] which results in increased uptake of Taurocholic Acid] CTD PMID:32294204 NCBI chr15:65,045,387...65,053,397
Ensembl chr15:65,045,387...65,053,397 		JBrowse link
josamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACLY ATP citrate lyase affects response to substance EXP ACLY protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G ARF1 ADP ribosylation factor 1 affects response to substance EXP ARF1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,708...228,099,212 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta affects response to substance EXP ATP5F1B protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b affects response to substance EXP ATP5F1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d affects response to substance EXP ATP5PD protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985 		JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP affects response to substance EXP ATP5PO protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814 		JBrowse link
G ATRX ATRX chromatin remodeler affects response to substance EXP ATRX protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233 		JBrowse link
G CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit affects response to substance EXP CLPP protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr19:6,361,531...6,370,242
Ensembl chr19:6,361,531...6,370,242 		JBrowse link
G CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X affects response to substance EXP CLPX protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr15:65,148,219...65,185,342
Ensembl chr15:65,148,219...65,185,342 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) decreases expression
multiple interactions		 EXP Josamycin results in decreased expression of CR1 protein
Ribomunyl inhibits the reaction [Josamycin results in decreased expression of CR1 protein]		 CTD PMID:8096833 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765 		JBrowse link
G CS citrate synthase affects response to substance EXP CS protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391 		JBrowse link
G DAZAP1 DAZ associated protein 1 affects response to substance EXP DAZAP1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr19:1,407,586...1,435,684
Ensembl chr19:1,407,569...1,435,687 		JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 affects response to substance EXP EIF2AK1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175 		JBrowse link
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 affects response to substance EXP EIF4G1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 3:184,314,606...184,335,358
Ensembl chr 3:184,314,495...184,335,358 		JBrowse link
G FBXO11 F-box protein 11 affects response to substance EXP FBXO11 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 2:47,806,920...47,906,498
Ensembl chr 2:47,789,316...47,906,498 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Josamycin results in increased expression of FOS mRNA; Josamycin results in increased expression of FOS protein CTD PMID:32454074 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha affects response to substance EXP GADD45A protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GFM2 GTP dependent ribosome recycling factor mitochondrial 2 affects response to substance EXP GFM2 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 5:74,721,206...74,767,117
Ensembl chr 5:74,721,206...74,767,147 		JBrowse link
G GPI glucose-6-phosphate isomerase decreases response to substance EXP GPI protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413 		JBrowse link
G HK2 hexokinase 2 decreases response to substance EXP HK2 protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 affects response to substance EXP HNRNPA1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088 		JBrowse link
G ITGB2 integrin subunit beta 2 multiple interactions
decreases expression		 EXP Ribomunyl inhibits the reaction [Josamycin results in decreased expression of ITGB2 protein] CTD PMID:8096833 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 affects response to substance EXP MAP2K3 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232 		JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 decreases response to substance EXP MAP3K4 protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr 6:160,991,769...161,117,380
Ensembl chr 6:160,991,727...161,117,385 		JBrowse link
G ME2 malic enzyme 2 affects response to substance EXP ME2 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr18:50,879,118...50,954,257
Ensembl chr18:50,879,080...50,954,257 		JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP Josamycin results in decreased expression of COX2 protein CTD PMID:31915244 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269 		JBrowse link
G MTFMT mitochondrial methionyl-tRNA formyltransferase decreases response to substance EXP MTFMT protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr15:65,001,512...65,029,639
Ensembl chr15:65,001,512...65,029,639 		JBrowse link
G MTIF2 mitochondrial translational initiation factor 2 decreases response to substance EXP MTIF2 protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr 2:55,236,595...55,269,248
Ensembl chr 2:55,236,595...55,269,347 		JBrowse link
G MTIF3 mitochondrial translational initiation factor 3 decreases response to substance EXP MTIF3 protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr13:27,435,643...27,450,564
Ensembl chr13:27,435,643...27,450,591 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 affects response to substance EXP NDUFB8 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000 		JBrowse link
G NPM1 nucleophosmin 1 affects response to substance EXP NPM1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810 		JBrowse link
G PCM1 pericentriolar material 1 affects response to substance EXP PCM1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 8:17,922,988...18,029,948
Ensembl chr 8:17,922,842...18,029,948 		JBrowse link
G PFKP phosphofructokinase, platelet decreases response to substance EXP PFKP protein results in decreased susceptibility to Josamycin CTD PMID:31915244 NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718 		JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B affects response to substance EXP PPP1R15B protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:204,395,826...204,411,817
Ensembl chr 1:204,396,492...204,411,887 		JBrowse link
G PPP2R2A protein phosphatase 2 regulatory subunit Balpha affects response to substance EXP PPP2R2A protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 8:26,291,508...26,372,680
Ensembl chr 8:26,291,508...26,372,680 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit affects response to substance EXP PRKDC protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G RTRAF RNA transcription, translation and transport factor affects response to substance EXP RTRAF protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr14:51,989,546...52,010,694
Ensembl chr14:51,989,514...52,010,694 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 affects response to substance EXP SLC16A1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase affects response to substance EXP SMG1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr16:18,804,860...18,926,408
Ensembl chr16:18,804,860...18,926,408 		JBrowse link
G SMG7 SMG7 nonsense mediated mRNA decay factor affects response to substance EXP SMG7 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:183,472,499...183,554,191
Ensembl chr 1:183,472,216...183,598,246 		JBrowse link
G STRAP serine/threonine kinase receptor associated protein affects response to substance EXP STRAP protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr12:15,882,387...15,903,478
Ensembl chr12:15,882,387...15,903,478 		JBrowse link
G TAF3 TATA-box binding protein associated factor 3 affects response to substance EXP TAF3 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr10:7,818,505...8,016,631
Ensembl chr10:7,818,497...8,016,631 		JBrowse link
G TAF4 TATA-box binding protein associated factor 4 affects response to substance EXP TAF4 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr20:61,974,798...62,065,881
Ensembl chr20:61,953,469...62,065,881 		JBrowse link
G TPX2 TPX2 microtubule nucleation factor affects response to substance EXP TPX2 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr20:31,739,290...31,801,800
Ensembl chr20:31,739,271...31,801,805 		JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 affects response to substance EXP TRIAP1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr12:120,443,964...120,446,384
Ensembl chr12:120,443,964...120,446,384 		JBrowse link
G UBAP2L ubiquitin associated protein 2 like affects response to substance EXP UBAP2L protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 1:154,220,172...154,271,510
Ensembl chr 1:154,220,179...154,271,510 		JBrowse link
G VDAC1 voltage dependent anion channel 1 affects response to substance EXP VDAC1 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G VDAC2 voltage dependent anion channel 2 affects response to substance EXP VDAC2 protein affects the susceptibility to Josamycin CTD PMID:31915244 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448 		JBrowse link
natamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLU clusterin increases expression ISO Natamycin results in increased expression of CLU mRNA CTD PMID:22863853 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CP ceruloplasmin increases expression ISO Natamycin results in increased expression of CP mRNA CTD PMID:22863853 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G FGA fibrinogen alpha chain increases expression ISO Natamycin results in increased expression of FGA mRNA CTD PMID:22863853 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGG fibrinogen gamma chain increases expression ISO Natamycin results in increased expression of FGG mRNA CTD PMID:22863853 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 increases expression ISO Natamycin results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G KRT19 keratin 19 increases expression ISO Natamycin results in increased expression of KRT19 mRNA CTD PMID:22863853 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G LCN2 lipocalin 2 increases expression ISO Natamycin results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression ISO Natamycin results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression ISO Natamycin results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
nystatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP Nystatin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G CASP8 caspase 8 multiple interactions EXP Nystatin inhibits the reaction [resveratrol affects the localization of CASP8 protein] CTD PMID:12902349 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAV1 caveolin 1 multiple interactions EXP Nystatin inhibits the reaction [Quercetin affects the localization of CAV1 protein] CTD PMID:17876056 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CD40 CD40 molecule increases expression ISO Nystatin results in increased expression of CD40 protein CTD PMID:16374455 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD80 CD80 molecule increases expression ISO Nystatin results in increased expression of CD80 protein CTD PMID:16374455 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD86 CD86 molecule increases expression ISO Nystatin results in increased expression of CD86 protein CTD PMID:16374455 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CLU clusterin increases expression ISO Nystatin results in increased expression of CLU mRNA CTD PMID:22863853 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CP ceruloplasmin increases expression ISO Nystatin results in increased expression of CP mRNA CTD PMID:22863853 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G FADD Fas associated via death domain multiple interactions EXP Nystatin inhibits the reaction [resveratrol affects the localization of FADD protein] CTD PMID:12902349 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions EXP Nystatin inhibits the reaction [resveratrol affects the localization of FAS protein] CTD PMID:12902349 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FGA fibrinogen alpha chain increases expression ISO Nystatin results in increased expression of FGA mRNA CTD PMID:22863853 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGG fibrinogen gamma chain increases expression ISO Nystatin results in increased expression of FGG mRNA CTD PMID:22863853 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 increases expression ISO Nystatin results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression ISO Nystatin results in increased expression of ICAM1 protein CTD PMID:16374455 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL1B interleukin 1 beta increases expression ISO Nystatin results in increased expression of IL1B mRNA; Nystatin results in increased expression of IL1B protein CTD PMID:16374455 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 increases expression ISO Nystatin results in increased expression of IL6 protein CTD PMID:16374455 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KRT18 keratin 18 increases expression ISO Nystatin results in increased expression of KRT18 mRNA CTD PMID:22863853 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT19 keratin 19 increases expression ISO Nystatin results in increased expression of KRT19 mRNA CTD PMID:22863853 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G KRT8 keratin 8 increases expression ISO Nystatin results in increased expression of KRT8 mRNA CTD PMID:22863853 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954 		JBrowse link
G LCN2 lipocalin 2 increases expression ISO Nystatin results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO Nystatin inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Estriol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Estrone results in increased phosphorylation of MAPK1 protein] CTD PMID:15072920 PMID:22230296 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO Nystatin inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Estrone results in increased phosphorylation of MAPK3 protein] CTD PMID:15072920 PMID:22230296 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G PRNP prion protein (Kanno blood group) multiple interactions EXP
ISO		 Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] CTD PMID:11994310 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit increases activity ISO Nystatin results in increased activity of REL protein CTD PMID:16374455 NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases activity ISO Nystatin results in increased activity of RELA protein CTD PMID:16374455 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression ISO Nystatin results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression ISO Nystatin results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a multiple interactions EXP Nystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10A protein] CTD PMID:17876056 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b multiple interactions EXP Nystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10B protein] CTD PMID:17876056 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G VIM vimentin increases expression ISO Nystatin results in increased expression of VIM mRNA CTD PMID:22863853 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
oligomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 increases activity ISO Oligomycin increases activity of Map3k7 protein in cardiac muscle cells RGD PMID:17085580 RGD:155791450 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
oligomycin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V1H ATPase H+ transporting V1 subunit H multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA CTD PMID:28366621 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO oligomycin A inhibits the reaction [bisphenol A results in increased expression of BCL2 protein] CTD PMID:24909818 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CCNA2 cyclin A2 multiple interactions ISO oligomycin A inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein] CTD PMID:24909818 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 multiple interactions ISO oligomycin A inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein] CTD PMID:24909818 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 multiple interactions ISO [bisphenol A co-treated with oligomycin A] results in decreased expression of CCND1 protein CTD PMID:24909818 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNE1 cyclin E1 multiple interactions ISO [bisphenol A co-treated with oligomycin A] results in decreased expression of CCNE1 protein CTD PMID:24909818 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CD14 CD14 molecule increases expression EXP oligomycin A results in increased expression of CD14 protein CTD PMID:26036281 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G FUT4 fucosyltransferase 4 increases expression EXP oligomycin A results in increased expression of FUT4 protein CTD PMID:26036281 NCBI chr11:94,543,921...94,549,895
Ensembl chr11:94,543,921...94,549,895 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA CTD PMID:28366621 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G PINK1 PTEN induced kinase 1 multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein]; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA]; PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions EXP [oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein] CTD PMID:28366621 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions EXP [oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA] CTD PMID:28366621 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TFEB transcription factor EB multiple interactions EXP [oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259 		JBrowse link
oligomycin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity EXP oligomycin B results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
radicicol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor decreases expression
multiple interactions		 EXP monorden results in decreased expression of AHR protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [monorden results in decreased expression of AHR protein]		 CTD PMID:20057149 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP monorden inhibits the reaction [Demecolcine results in increased activity of CASP3 protein] CTD PMID:12530016 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G ELN elastin increases expression EXP monorden results in increased expression of ELN protein CTD PMID:21880723 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G ESR1 estrogen receptor 1 decreases expression EXP monorden analog results in decreased expression of ESR1 protein; monorden results in decreased expression of ESR1 protein CTD PMID:11448926 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions ISO monorden inhibits the reaction [cobaltous chloride results in increased expression of and affects the localization of GJA1 protein] CTD PMID:29155206 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions ISO [monorden co-treated with cobaltous chloride] results in increased expression of HIF1A protein CTD PMID:29155206 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP monorden analog results in increased expression of HSPA1A protein; monorden results in increased expression of HSPA1A protein CTD PMID:11448926 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO monorden inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein] CTD PMID:15808840 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity
decreases expression		 EXP monorden results in decreased activity of KCNH2 protein
monorden results in decreased expression of KCNH2 protein modified form		 CTD PMID:12775586 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO monorden inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15583003 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G P2RX1 purinergic receptor P2X 1 multiple interactions ISO monorden promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1] CTD PMID:11930156 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G PGR progesterone receptor decreases expression EXP monorden analog results in decreased expression of PGR protein alternative form CTD PMID:11448926 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G RB1 RB transcriptional corepressor 1 affects phosphorylation EXP monorden affects the phosphorylation of RB1 protein CTD PMID:21880723 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RNGTT RNA guanylyltransferase and 5'-phosphatase decreases expression EXP monorden results in decreased expression of RNGTT protein CTD PMID:30166341 NCBI chr 6:88,609,897...88,963,618
Ensembl chr 6:88,609,897...88,963,618 		JBrowse link
G VLDLR very low density lipoprotein receptor multiple interactions ISO monorden inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein] CTD PMID:15808840 NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056 		JBrowse link
spinosad term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
decreases activity		 EXP spinosad inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of Ivermectin]
spinosad results in decreased activity of ABCB1 protein		 CTD PMID:21321059 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit decreases response to substance EXP CHRNA7 protein mutant form results in decreased susceptibility to spinosad CTD PMID:23016960 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018 		JBrowse link
troleandomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO
EXP		 Troleandomycin inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]		 CTD PMID:12235267 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases activity
multiple interactions
increases expression
increases activity		 EXP Troleandomycin results in decreased activity of CYP3A4 protein
[Troleandomycin results in decreased activity of CYP3A4 protein] which results in decreased chemical synthesis of N-desmethyltamoxifen; [Troleandomycin results in decreased activity of CYP3A4 protein] which results in decreased metabolism of Tamoxifen; Troleandomycin inhibits the reaction [CYP3A4 protein results in decreased methylation of adinazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Cholecalciferol]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased metabolism of 4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased metabolism of Fluoxetine]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased metabolism of laquinimod]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased metabolism of triflumuron]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased oxidation of Methylenebis(chloroaniline)]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased oxidation of Nifedipine]; Troleandomycin promotes the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Troleandomycin results in increased expression of and results in increased activity of CYP3A4 protein
Troleandomycin results in increased expression of CYP3A4 mRNA
Troleandomycin results in increased activity of CYP3A4 protein		 CTD PMID:1740010 PMID:2271712 PMID:9512926 PMID:9600717 PMID:11409940 More... NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 multiple interactions
decreases activity		 EXP Troleandomycin inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]
Troleandomycin results in decreased activity of CYP3A5 protein		 CTD PMID:15557344 PMID:15731592 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G FN1 fibronectin 1 increases expression ISO Troleandomycin results in increased expression of FN1 mRNA CTD PMID:12971794 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G GSTA2 glutathione S-transferase alpha 2 increases expression ISO Troleandomycin results in increased expression of GSTA2 mRNA CTD PMID:12971794 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G HBG2 hemoglobin subunit gamma 2 multiple interactions EXP Troleandomycin inhibits the reaction [Primaquine results in increased expression of HBG2 protein] CTD PMID:19616568 NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605 		JBrowse link
G MADCAM1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions ISO Troleandomycin inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] CTD PMID:12388057 NCBI chr19:496,486...505,343
Ensembl chr19:489,176...505,343 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP Troleandomycin binds to and results in increased activity of NR1I2 protein CTD PMID:15039302 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Troleandomycin inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] CTD PMID:12388057 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
verrucarin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2 interleukin 2 increases expression
affects secretion		 ISO muconomycin A results in increased expression of IL2 mRNA
muconomycin A affects the secretion of IL2 protein		 CTD PMID:8560498 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 affects secretion
increases expression		 ISO muconomycin A affects the secretion of IL4 protein
muconomycin A results in increased expression of IL4 mRNA		 CTD PMID:8560498 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 affects secretion ISO muconomycin A affects the secretion of IL5 protein CTD PMID:8560498 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 increases expression ISO muconomycin A results in increased expression of IL6 mRNA CTD PMID:8560498 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    role 25957
      biological role 25936
        antimicrobial agent 21902
          macrolide antibiotic 772
            (+)-aplasmomycin 0
            (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-10-amino-6-\{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy\}-14-ethyl-7,12-dihydroxy-4-\{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy\}-13-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 0
            (9S)-erythromycyclamine 0
            10-deoxymethymycin + 0
            20-oxo-5-O-beta-mycaminosyltylactone 0
            21-deoxyconcanamycin A 0
            5-O-beta-D-mycaminosyl-20-oxotylonolide 0
            5-O-beta-D-mycaminosyltylactone 0
            5-O-mycaminosyltylonolide 0
            NK154183A 0
            NK154183B 0
            PF 1163A 0
            PF 1163B 0
            amphotericin B + 390
            azithromycin + 33
            bafilomycin A1 91
            boromycin 0
            brasilinolide A 0
            brasilinolide B 0
            brefeldin A + 36
            candicidin D + 0
            cethromycin 0
            clarithromycin 27
            concanamycin + 7
            dalfopristin 0
            demethyllactenocin 0
            demethylmacrocin 0
            dirithromycin 0
            erythromycins + 177
            etnangien 0
            fidaxomicin 2
            gamithromycin 0
            josamycin 48
            leucomycin V 0
            macrocin 0
            macrolide pesticide + 57
            methymycin 0
            migrastatin 0
            mycinamicin + 0
            narbomycin 0
            natamycin 9
            neomethymycin 0
            neopikromycin 0
            novamethymycin 0
            novapikromycin 0
            nystatin 30
            nystatins + 30
            oligomycin + 15
            ossamycin 0
            phomacin A 0
            phomacin B 0
            pikromycin 0
            pristinamycin IIA + 0
            radicicol 15
            reedsmycin A 0
            reedsmycin B 0
            reedsmycin C 0
            reedsmycin D 0
            reedsmycin E 0
            rhizoxin 0
            rosaramicin 0
            staphcoccomycin 0
            tilmicosin 0
            troleandomycin 9
            tylosin 0
            verrucarin A 4
            virginiamycin S1 + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            heteroorganic entity 24773
                              organochalcogen compound 24384
                                organooxygen compound 24061
                                  ester 18759
                                    carboxylic ester 17841
                                      lactone 12966
                                        macrocyclic lactone 6094
                                          macrolide 6018
                                            macrolide antibiotic 772
                                              (+)-aplasmomycin 0
                                              (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-10-amino-6-\{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy\}-14-ethyl-7,12-dihydroxy-4-\{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy\}-13-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 0
                                              (9S)-erythromycyclamine 0
                                              10-deoxymethymycin + 0
                                              20-oxo-5-O-beta-mycaminosyltylactone 0
                                              21-deoxyconcanamycin A 0
                                              5-O-beta-D-mycaminosyl-20-oxotylonolide 0
                                              5-O-beta-D-mycaminosyltylactone 0
                                              5-O-mycaminosyltylonolide 0
                                              NK154183A 0
                                              NK154183B 0
                                              PF 1163A 0
                                              PF 1163B 0
                                              amphotericin B + 390
                                              azithromycin + 33
                                              bafilomycin A1 91
                                              boromycin 0
                                              brasilinolide A 0
                                              brasilinolide B 0
                                              brefeldin A + 36
                                              candicidin D + 0
                                              cethromycin 0
                                              clarithromycin 27
                                              concanamycin + 7
                                              dalfopristin 0
                                              demethyllactenocin 0
                                              demethylmacrocin 0
                                              dirithromycin 0
                                              erythromycins + 177
                                              etnangien 0
                                              fidaxomicin 2
                                              gamithromycin 0
                                              josamycin 48
                                              leucomycin V 0
                                              macrocin 0
                                              macrolide pesticide + 57
                                              methymycin 0
                                              migrastatin 0
                                              mycinamicin + 0
                                              narbomycin 0
                                              natamycin 9
                                              neomethymycin 0
                                              neopikromycin 0
                                              novamethymycin 0
                                              novapikromycin 0
                                              nystatin 30
                                              nystatins + 30
                                              oligomycin + 15
                                              ossamycin 0
                                              phomacin A 0
                                              phomacin B 0
                                              pikromycin 0
                                              pristinamycin IIA + 0
                                              radicicol 15
                                              reedsmycin A 0
                                              reedsmycin B 0
                                              reedsmycin C 0
                                              reedsmycin D 0
                                              reedsmycin E 0
                                              rhizoxin 0
                                              rosaramicin 0
                                              staphcoccomycin 0
                                              tilmicosin 0
                                              troleandomycin 9
                                              tylosin 0
                                              verrucarin A 4
                                              virginiamycin S1 + 0
paths to the root