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G |
Slco4c1 |
solute carrier organic anion transporter family, member 4C1 |
increases export |
ISO |
SLCO4C1 protein results in increased export of Homoarginine |
CTD |
PMID:30865704 |
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NCBI chr 9:104,301,935...104,350,262
Ensembl chr 9:104,299,277...104,350,308
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G |
Egf |
epidermal growth factor |
multiple interactions |
EXP |
[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine] |
CTD |
PMID:22689575 |
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NCBI chr 2:68,820,616...68,895,537
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G |
Ace |
angiotensin I converting enzyme |
decreases activity |
ISO |
Lisinopril analog results in decreased activity of ACE protein |
CTD |
PMID:22200082 |
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NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
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G |
Ace2 |
angiotensin I converting enzyme 2 |
increases expression increases activity |
EXP |
Lisinopril results in increased expression of ACE2 mRNA Lisinopril results in increased activity of ACE2 protein |
CTD |
PMID:15897343 PMID:16221218 |
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NCBI chr X:32,050,734...32,095,860
Ensembl chr X:32,049,931...32,096,016
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G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein] Lisinopril inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein] |
CTD |
PMID:23060470 PMID:31710167 |
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NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
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G |
Agt |
angiotensinogen |
decreases expression multiple interactions decreases secretion increases secretion affects response to substance increases expression |
ISO EXP |
Lisinopril results in decreased expression of AGT protein [Lisinopril co-treated with Losartan] results in increased expression of AGT mRNA Lisinopril results in decreased secretion of AGT protein Lisinopril results in increased secretion of AGT protein alternative form AGT gene alternative form affects the susceptibility to Lisinopril Lisinopril results in increased expression of AGT mRNA |
CTD |
PMID:8393685 PMID:8915971 PMID:15897343 PMID:16221218 PMID:16685205 |
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NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
Lisinopril results in decreased expression of BCL2 |
CTD |
PMID:10075388 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Cd2ap |
CD2-associated protein |
multiple interactions |
EXP |
Lisinopril inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein] |
CTD |
PMID:16636307 |
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NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
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G |
Edn1 |
endothelin 1 |
decreases secretion |
ISO |
Lisinopril results in decreased secretion of EDN1 protein |
CTD |
PMID:19079593 |
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NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
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G |
Gh1 |
growth hormone 1 |
multiple interactions |
EXP |
[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] |
CTD |
PMID:20051877 |
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NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein] |
CTD |
PMID:19225054 |
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NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
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G |
Hpse |
heparanase |
multiple interactions |
EXP |
[Spironolactone co-treated with Lisinopril] inhibits the reaction [Doxorubicin results in increased expression of HPSE protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HPSE protein] |
CTD |
PMID:19429930 |
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NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
increases expression |
ISO |
Lisinopril results in increased expression of IGFBP1 protein |
CTD |
PMID:9663927 |
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NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
EXP |
[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein] |
CTD |
PMID:20051877 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein] |
CTD |
PMID:23060470 |
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NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] |
CTD |
PMID:20051877 |
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NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
multiple interactions |
EXP |
Lisinopril inhibits the reaction [Doxorubicin results in decreased phosphorylation of NPHS1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NPHS1 protein] |
CTD |
PMID:16636307 PMID:19293598 |
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NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559
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G |
Nphs2 |
NPHS2 stomatin family member, podocin |
multiple interactions |
EXP |
Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 mRNA]; Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 protein] |
CTD |
PMID:16636307 |
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NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
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G |
Nppa |
natriuretic peptide A |
decreases expression |
ISO |
Lisinopril results in decreased expression of NPPA protein |
CTD |
PMID:8393685 |
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NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
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G |
Ren |
renin |
increases expression multiple interactions |
ISO EXP |
Lisinopril results in increased expression of REN protein [Lisinopril co-treated with Losartan] results in increased expression of REN mRNA Lisinopril results in increased expression of REN mRNA |
CTD |
PMID:2550029 PMID:8915971 PMID:16221218 |
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NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
EXP |
[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] |
CTD |
PMID:20051877 |
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NCBI chr X:1,364,771...1,369,451
Ensembl chr X:1,364,786...1,369,384
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of VEGFA protein] |
CTD |
PMID:19293598 |
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NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] |
CTD |
PMID:30896085 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] |
CTD |
PMID:30896085 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Cat |
catalase |
multiple interactions |
EXP ISO |
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein] royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein] |
CTD |
PMID:20369241 PMID:30896085 |
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NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases activity affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein] royal jelly results in increased activity of ESR1 protein |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] |
CTD |
PMID:30896085 |
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NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
royal jelly results in increased expression of TFF1 mRNA |
CTD |
PMID:15946813 |
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NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] |
CTD |
PMID:30896085 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO EXP |
royal jelly results in increased expression of VEGFA mRNA |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
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