isoindoles - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	isoindoles	go back to main search page
Accession:	CHEBI:24897	browse the term
Synonyms:	xref_mesh:	MESH:D054833

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Rat (1152) Mouse (1241) Human (1173) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (1152)

isoindoles

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ALG12, alpha-1,6-mannosyltransferase

affects response to substance

ALG12 gene SNP affects the susceptibility to Isoindoles analog

NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458

G

kinase suppressor of ras 2

affects response to substance

KSR2 gene SNP affects the susceptibility to Isoindoles analog

NCBI chr12:38,802,796...39,187,809
Ensembl chr12:38,802,004...39,188,375

G

mitochondrial ribosomal protein S27

affects response to substance

MRPS27 gene SNP affects the susceptibility to Isoindoles analog

NCBI chr 2:30,740,007...30,808,577
Ensembl chr 2:30,740,033...30,808,577

G

nebulette

affects response to substance

NEBL gene SNP affects the susceptibility to Isoindoles analog

NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210

4,5-dianilinophthalimide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

epidermal growth factor

multiple interactions

4,5-dianilinophthalimide inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone]

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

5-Hydroxythalidomide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member A1

affects binding

5-hydroxythalidomide binds to ALDH1A1 protein

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

argininosuccinate synthase 1

affects binding

5-hydroxythalidomide binds to ASS1 protein

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATP synthase F1 subunit alpha

affects binding

5-hydroxythalidomide binds to ATP5F1A protein

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATP synthase membrane subunit e

affects binding

5-hydroxythalidomide binds to ATP5ME protein

NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013

G

3-hydroxybutyrate dehydrogenase 1

affects binding

5-hydroxythalidomide binds to BDH1 protein

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

carbonic anhydrase 3

affects binding

5-hydroxythalidomide binds to CAR3 protein
5-hydroxythalidomide binds to CA3 protein

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

cytochrome c oxidase subunit 6A1

affects binding

5-hydroxythalidomide binds to COX6A1 protein

NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041

G

cytochrome c oxidase subunit 6B1

affects binding

5-hydroxythalidomide binds to COX6B1 protein

NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001

G

cytochrome P450, subfamily 2, polypeptide 11

increases metabolic processing

CYP2C18 protein results in increased metabolism of 5-hydroxythalidomide

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily C, polypeptide 6

increases abundance
multiple interactions

CYP2C19 protein results in increased abundance of 5'-hydroxythalidomide; CYP2C19 protein results in increased abundance of 5-hydroxythalidomide
[CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5'-hydroxythalidomide; [CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; [CYP2C19 protein results in increased oxidation of Thalidomide] which results in increased abundance of 5'-hydroxythalidomide; [CYP2C19 protein results in increased oxidation of Thalidomide] which results in increased abundance of 5-hydroxythalidomide

PMID:20443640 PMID:24350712

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily j, polypeptide 4

increases metabolic processing

CYP2J2 protein results in increased metabolism of 5-hydroxythalidomide

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

[CYP3A4 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; CYP3A4 protein results in increased oxidation of and results in increased glutathionylation of 5-hydroxythalidomide

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

[CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; CYP3A5 protein results in increased oxidation of and results in increased glutathionylation of 5-hydroxythalidomide

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

enolase 1

affects binding

5-hydroxythalidomide binds to ENO1 protein

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

fatty acid binding protein 1

affects binding

5-hydroxythalidomide binds to FABP1 protein

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

ferritin light chain 1

affects binding

5-hydroxythalidomide binds to FTL protein
5-hydroxythalidomide binds to FTL1 protein

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

glutathione S-transferase alpha 1

affects binding

5-hydroxythalidomide binds to GSTA1 protein

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 5

affects binding

5-hydroxythalidomide binds to GSTA1 protein

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

affects binding

5-hydroxythalidomide binds to GSTM1 protein

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

phosphatidylethanolamine binding protein 1

affects binding

5-hydroxythalidomide binds to PEBP1 protein

NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862

G

regucalcin

affects binding

5-hydroxythalidomide binds to RGN protein

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

G

ubiquinol-cytochrome c reductase binding protein

affects binding

5-hydroxythalidomide binds to UQCRB protein

NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150

apremilast

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased activity of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

creatine kinase, M-type

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased secretion of CKM protein]

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

glutamic-oxaloacetic transaminase 1

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased secretion of GOT1 protein]

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

lactate dehydrogenase A

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased secretion of LDHA protein]

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

mitogen activated protein kinase 1

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased expression of MAPK1 mRNA]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen-activated protein kinase 8

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased expression of MAPK8 mRNA]

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

NFKB inhibitor alpha

multiple interactions

apremilast inhibits the reaction [carfilzomib results in decreased expression of NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased expression of RELA mRNA]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

captafol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

iodothyronine deiodinase 1

decreases activity

captafol results in decreased activity of DIO1 protein

PMID:29228274 PMID:30561685

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

iodothyronine deiodinase 2

decreases activity

captafol results in decreased activity of DIO2 protein

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

iodothyronine deiodinase 3

decreases activity

captafol results in decreased activity of DIO3 protein

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

glutathione S-transferase pi 1

multiple interactions
decreases activity

hexylglutathione inhibits the reaction [captafol results in decreased activity of GSTP1 protein]

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

proliferating cell nuclear antigen

increases expression
multiple interactions

captafol results in increased expression of PCNA protein
Cysteine inhibits the reaction [captafol results in increased expression of PCNA protein]

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

trefoil factor 1

decreases expression

captafol results in decreased expression of TFF1 mRNA

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

DNA topoisomerase I

decreases activity

captafol results in decreased activity of TOP1 protein

NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623

G

DNA topoisomerase II alpha

decreases activity

captafol results in decreased activity of TOP2A protein

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

captan

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

increases expression

Captan results in increased expression of ABCB1A mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

multiple interactions

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

multiple interactions
increases expression

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA
Captan results in increased expression of ABCC3 mRNA

PMID:31558096 PMID:32745781

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 5

increases expression

Captan results in increased expression of ABCC5 mRNA

NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253

G

ATP binding cassette subfamily C member 9

decreases expression

Captan results in decreased expression of ABCC9 mRNA

NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356

G

ATP binding cassette subfamily F member 1

increases expression

Captan results in increased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

abhydrolase domain containing 6, acylglycerol lipase

increases expression

Captan results in increased expression of ABHD6 mRNA

NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985

G

acetyl-CoA acyltransferase 1A

increases expression

Captan results in increased expression of ACAA1A mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

Captan results in increased expression of ACAA1B mRNA

NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA acetyltransferase 2

increases expression

Captan results in increased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

angiotensin I converting enzyme

decreases expression

Captan results in decreased expression of ACE mRNA

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

acyl-CoA oxidase 1

multiple interactions
increases expression

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA
Captan results in increased expression of ACOX1 mRNA

PMID:31558096 PMID:32736067

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

actin alpha 2, smooth muscle

decreases expression

Captan results in decreased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

aldo-keto reductase family 1 member B10

increases expression

Captan results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

AKT serine/threonine kinase 1

multiple interactions

[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

5'-aminolevulinate synthase 1

increases expression

Captan results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

aldehyde dehydrogenase 1 family, member A1

increases expression

Captan results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

increases expression

Captan results in increased expression of ALDH2 mRNA

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A2

increases expression

Captan results in increased expression of ALDH3A2 mRNA

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 7 family, member A1

decreases expression

Captan results in decreased expression of ALDH7A1 mRNA

NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193

G

aldolase, fructose-bisphosphate B

increases expression

Captan results in increased expression of ALDOB mRNA

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

aldolase, fructose-bisphosphate C

increases expression

Captan results in increased expression of ALDOA mRNA; Captan results in increased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

arachidonate 5-lipoxygenase activating protein

decreases expression

Captan results in decreased expression of ALOX5AP mRNA

NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986

G

anti-Mullerian hormone

decreases expression

Captan results in decreased expression of AMH protein

NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282

G

adaptor related protein complex 2 subunit mu 1

increases expression

Captan results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

apolipoprotein A1

increases expression

Captan results in increased expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein C3

increases expression

Captan results in increased expression of APOC3 mRNA

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein E

decreases expression

Captan results in decreased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

aquaporin 1

decreases expression

Captan results in decreased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 3 (Gill blood group)

increases expression

Captan results in increased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

ADP-ribosylation factor 1

increases expression

Captan results in increased expression of ARF1 mRNA

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

Rho GTPase activating protein 9

decreases expression

Captan results in decreased expression of ARHGAP9 mRNA

NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524

G

AT-rich interaction domain 4B

decreases expression

Captan results in decreased expression of ARID4B mRNA

NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906

G

ADP-ribosylation factor like GTPase 1

increases expression

Captan results in increased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

aryl hydrocarbon receptor nuclear translocator

decreases expression

Captan results in decreased expression of ARNT mRNA

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

Captan results in increased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

actin related protein 2/3 complex, subunit 3

decreases expression

Captan results in decreased expression of ARPC3 mRNA

NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651

G

cAMP-regulated phosphoprotein 19

increases expression

Captan results in increased expression of ARPP19 mRNA

NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452

G

arylsulfatase A

increases expression

Captan results in increased expression of ARSA mRNA

NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783

G

asporin

decreases expression

Captan results in decreased expression of ASPN mRNA

NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041

G

argininosuccinate synthase 1

decreases expression

Captan results in decreased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATPase family, AAA domain containing 3A

increases expression

Captan results in increased expression of ATAD3A mRNA

NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482

G

autophagy related 3

increases expression

Captan results in increased expression of ATG3 mRNA

NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224

G

ATM interactor

decreases expression

Captan results in decreased expression of ATMIN mRNA

NCBI chr19:44,996,506...45,013,606
Ensembl chr19:44,996,356...45,013,605

G

ATPase Na+/K+ transporting subunit alpha 2

decreases expression

Captan results in decreased expression of ATP1A2 mRNA

NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544

G

ATP synthase F1 subunit beta

increases expression

Captan results in increased expression of ATP5F1B mRNA

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase F1 subunit epsilon

increases expression

Captan results in increased expression of ATP5F1E mRNA

NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450

G

ATPase H+ transporting V0 subunit D1

increases expression

Captan results in increased expression of ATP6V0D1 mRNA

NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450

G

ATPase H+ transporting V1 subunit D

increases expression

Captan results in increased expression of ATP6V1D mRNA

NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303

G

beta-1,4-galactosyltransferase 1

increases expression

Captan results in increased expression of B4GALT1 mRNA

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

BCL2 associated X, apoptosis regulator

increases expression

Captan results in increased expression of BAX protein

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

decreases expression

Captan results in decreased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCL2, apoptosis regulator

decreases expression

Captan results in decreased expression of BCL2 mRNA; Captan results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

beclin 1

increases expression

Captan results in increased expression of BECN1 mRNA

PMID:31558096 PMID:34303901

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

biglycan

decreases expression

Captan results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

basic helix-loop-helix family, member e40

increases expression

Captan results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

biogenesis of lysosomal organelles complex-1, subunit 2

increases expression

Captan results in increased expression of BLOC1S2 mRNA

NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653

G

BCL2 interacting protein 3

increases expression

Captan results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

bisphosphoglycerate mutase

increases expression

Captan results in increased expression of BPGM mRNA

NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581

G

3'(2'), 5'-bisphosphate nucleotidase 1

increases expression

Captan results in increased expression of BPNT1 mRNA

NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503

G

complement C1q A chain

decreases expression

Captan results in decreased expression of C1QA mRNA

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

G

complement C1q B chain

decreases expression

Captan results in decreased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

decreases expression

Captan results in decreased expression of C1QC mRNA

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

C2 calcium-dependent domain containing 2

decreases expression

Captan results in decreased expression of C2CD2 mRNA

NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739

G

calcium binding and coiled coil domain 1

decreases expression

Captan results in decreased expression of CALCOCO1 mRNA

NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422

G

calreticulin

increases expression

Captan results in increased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

calnexin

decreases expression

Captan results in decreased expression of CANX mRNA

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

capping actin protein, gelsolin like

increases expression

Captan results in increased expression of CAPG mRNA

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

carbonic anhydrase 9

increases expression

Captan results in increased expression of CAR9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

caspase 3

increases expression
increases cleavage

Captan results in increased expression of CASP3 mRNA
Captan results in increased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

catalase

increases expression

Captan results in increased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

decreases expression

Captan results in decreased expression of CAV1 mRNA

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

caveolae associated protein 2

decreases expression

Captan results in decreased expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

G

carbonyl reductase 1

increases expression

Captan results in increased expression of CBR1 mRNA

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 3

increases expression

Captan results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

cyclin D1

multiple interactions

[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

decreases expression

Captan results in decreased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

chaperonin containing TCP1 subunit 5

decreases expression

Captan results in decreased expression of CCT5 mRNA

NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930

G

chaperonin containing TCP1 subunit 6A

decreases expression

Captan results in decreased expression of CCT6A mRNA

NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337

G

CD36 molecule

multiple interactions

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD74 molecule

decreases expression

Captan results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

cytidine deaminase

increases expression

Captan results in increased expression of CDA mRNA

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

G

cyclin-dependent kinase 19

decreases expression

Captan results in decreased expression of CDK19 mRNA

NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628

G

cyclin-dependent kinase 4

decreases expression

Captan results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1B

decreases expression

Captan results in decreased expression of CDKN1B mRNA

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

carboxylesterase 2C

increases expression

Captan results in increased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790

G

centrin 2

decreases expression

Captan results in decreased expression of CETN2 mRNA

NCBI chr X:150,769,944...150,774,833
Ensembl chr X:150,769,953...150,774,919

G

cysteine-rich hydrophobic domain 2

decreases expression

Captan results in decreased expression of CHIC2 mRNA

NCBI chr14:33,157,669...33,192,015
Ensembl chr14:33,157,537...33,191,895

G

charged multivesicular body protein 6

increases expression

Captan results in increased expression of CHMP6 mRNA

NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640

G

cell death-inducing DFFA-like effector c

increases expression

Captan results in increased expression of CIDEC mRNA

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

cold inducible RNA binding protein

decreases expression

Captan results in decreased expression of CIRBP mRNA

NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818

G

creatine kinase, M-type

decreases expression

Captan results in decreased expression of CKM mRNA

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

CAP-GLY domain containing linker protein 3

decreases expression

Captan results in decreased expression of CLIP3 mRNA

NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184

G

calsyntenin 1

decreases expression

Captan results in decreased expression of CLSTN1 mRNA

NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583

G

clathrin, light chain B

increases expression

Captan results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

cytidine/uridine monophosphate kinase 2

increases expression

Captan results in increased expression of CMPK2 mRNA

NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183

G

carnosine dipeptidase 2

increases expression

Captan results in increased expression of CNDP2 mRNA

NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922

G

calponin 3

decreases expression

Captan results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

component of oligomeric golgi complex 4

increases expression

Captan results in increased expression of COG4 mRNA

NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796

G

collagen type VI alpha 2 chain

decreases expression

Captan results in decreased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen type VI alpha 3 chain

decreases expression

Captan results in decreased expression of COL6A3 mRNA

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

catechol-O-methyltransferase

increases expression

Captan results in increased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

COPI coat complex subunit beta 2

increases expression

Captan results in increased expression of COPB2 mRNA

NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197

G

COP9 signalosome subunit 5

increases expression

Captan results in increased expression of COPS5 mRNA

NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731

G

COP9 signalosome subunit 7A

decreases expression

Captan results in decreased expression of COPS7A mRNA

NCBI chr 4:157,766,626...157,792,632
Ensembl chr 4:157,766,588...157,773,948

G

cytochrome c oxidase subunit 6B1

increases expression

Captan results in increased expression of COX6B1 mRNA

NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001

G

carbamoyl-phosphate synthase 1

increases expression

Captan results in increased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1A

multiple interactions

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

cAMP responsive element binding protein 3-like 3

increases expression

Captan results in increased expression of CREB3L3 mRNA

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

cysteine-rich with EGF-like domains 2

decreases expression

Captan results in decreased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

crystallin, alpha B

decreases expression

Captan results in decreased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

citrate synthase

increases expression

Captan results in increased expression of CS mRNA

NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421

G

cysteine and glycine-rich protein 1

decreases expression

Captan results in decreased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cystathionine gamma-lyase

increases expression

Captan results in increased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

catenin delta 1

increases expression

Captan results in increased expression of CTNND1 mRNA

NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516

G

cytochrome b-245 beta chain

decreases expression

Captan results in decreased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

Captan results in increased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression
multiple interactions

Captan results in increased expression of CYP2B10 mRNA
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA

PMID:31558096 PMID:32736067 PMID:32745781

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily c, polypeptide 24

multiple interactions

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2C55 mRNA

NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases expression
increases expression
multiple interactions

Captan results in decreased expression of CYP2C19 protein
Captan results in increased expression of CYP2C29 mRNA
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA

PMID:31558096 PMID:32194361 PMID:32745781

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased expression of CYP3A4 mRNA

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

D-box binding PAR bZIP transcription factor

increases expression

Captan results in increased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

dCTP pyrophosphatase 1

decreases expression

Captan results in decreased expression of DCTPP1 mRNA

NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839

G

DNA-damage inducible transcript 3

increases expression

Captan results in increased expression of DDIT3 mRNA
Captan results in increased expression of DDIT3 protein

PMID:32870474 PMID:34303901

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

deoxyribose-phosphate aldolase

increases expression

Captan results in increased expression of DERA mRNA

NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865

G

dihydrofolate reductase

increases expression

Captan results in increased expression of DHFR mRNA

NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713

G

iodothyronine deiodinase 1

decreases activity
decreases expression
multiple interactions

Captan results in decreased activity of DIO1 protein
Captan results in decreased expression of DIO1 mRNA
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA

PMID:29228274 PMID:31558096 PMID:32745781

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression

Captan results in increased expression of DNAJB6 mRNA

NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659

G

developmental pluripotency associated 5

increases expression

Captan results in increased expression of DPPA5A mRNA

NCBI chr 8:79,215,341...79,217,282
Ensembl chr 8:79,215,362...79,216,570
Ensembl chr 7:79,215,362...79,216,570

G

desmocollin 2

increases expression

Captan results in increased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

dual specificity phosphatase 3

decreases expression

Captan results in decreased expression of DUSP3 mRNA

NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962

G

dual specificity phosphatase 6

increases expression

Captan results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dynein light chain Tctex-type 3

increases expression

Captan results in increased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

E2F transcription factor 8

decreases expression

Captan results in decreased expression of E2F8 mRNA

NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098

G

enoyl-CoA delta isomerase 1

multiple interactions
increases expression

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA
Captan results in increased expression of ECI1 mRNA

PMID:31558096 PMID:32736067

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

eukaryotic translation initiation factor 2-alpha kinase 2

increases expression

Captan results in increased expression of EIF2AK2 mRNA

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2 subunit gamma

decreases expression

Captan results in decreased expression of EIF2S3X mRNA

NCBI chr X:58,916,513...58,939,923
Ensembl chr X:58,917,490...58,940,686

G

eukaryotic translation initiation factor 4 gamma 1

decreases expression

Captan results in decreased expression of EIF4G1 mRNA

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

ELOVL fatty acid elongase 5

decreases expression

Captan results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

ELOVL fatty acid elongase 6

increases expression

Captan results in increased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

epoxide hydrolase 1

increases expression

Captan results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

epoxide hydrolase 2

increases expression

Captan results in increased expression of EPHX2 mRNA

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

erb-b2 receptor tyrosine kinase 2

decreases expression

Captan results in decreased expression of ERBB2 mRNA

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

erb-b2 receptor tyrosine kinase 3

decreases expression

Captan results in decreased expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

endoplasmic reticulum oxidoreductase 1 beta

decreases expression

Captan results in decreased expression of ERO1B mRNA

NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398

G

estrogen receptor 1

affects binding

Captan binds to ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

decreases expression

Captan results in decreased expression of ESR2 protein

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

electron transfer flavoprotein subunit beta

increases expression

Captan results in increased expression of ETFB mRNA

NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068

G

Enah/Vasp-like

decreases expression

Captan results in decreased expression of EVL mRNA

NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344

G

fatty acid binding protein 1

increases expression

Captan results in increased expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 2

increases expression

Captan results in increased expression of FABP2 mRNA

NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089

G

FAT atypical cadherin 1

increases expression

Captan results in increased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

fibrillin 1

decreases expression

Captan results in decreased expression of FBN1 mRNA

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

F-box protein 5

decreases expression

Captan results in decreased expression of FBXO5 mRNA

NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437

G

Fc gamma receptor 2A

decreases expression

Captan results in decreased expression of FCGR3 mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

farnesyl diphosphate farnesyl transferase 1

increases expression

Captan results in increased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

fibroblast growth factor 1

decreases expression

Captan results in decreased expression of FGF1 mRNA

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fission, mitochondrial 1

increases expression

Captan results in increased expression of FIS1 mRNA

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

filamin A

decreases expression

Captan results in decreased expression of FLNA mRNA

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

flavin containing dimethylaniline monoxygenase 5

increases expression

Captan results in increased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

Captan results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box J3

increases expression

Captan results in increased expression of FOXJ3 mRNA

NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489

G

FYN proto-oncogene, Src family tyrosine kinase

decreases expression

Captan results in decreased expression of FYN mRNA

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

G

frizzled class receptor 7

decreases expression

Captan results in decreased expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

G0/G1switch 2

increases expression

Captan results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

GABA type A receptor-associated protein

increases expression

Captan results in increased expression of GABARAP mRNA

NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765

G

growth arrest and DNA-damage-inducible, gamma

decreases expression

Captan results in decreased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

UDP-galactose-4-epimerase

increases expression

Captan results in increased expression of GALE mRNA

NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

Captan results in increased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

glycyl-tRNA synthetase 1

decreases expression

Captan results in decreased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

glutamate-cysteine ligase, catalytic subunit

increases expression

Captan results in increased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

Captan results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glial fibrillary acidic protein

multiple interactions

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

GTPase, IMAP family member 4

decreases expression

Captan results in decreased expression of GIMAP4 mRNA

NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306

G

GTPase, IMAP family member 6

decreases expression

Captan results in decreased expression of GIMAP6 mRNA

NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116

G

glutamate-ammonia ligase

decreases expression

Captan results in decreased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

G protein subunit alpha i2

decreases expression

Captan results in decreased expression of GNAI2 mRNA

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

glycine N-methyltransferase

decreases expression

Captan results in decreased expression of GNMT mRNA

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

glucosamine-6-phosphate deaminase 1

increases expression

Captan results in increased expression of GNPDA1 mRNA

NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486

G

golgi transport 1B

decreases expression

Captan results in decreased expression of GOLT1B mRNA

NCBI chr 4:175,333,056...175,346,156
Ensembl chr 4:175,333,092...175,346,153

G

G protein-coupled receptor 17

increases expression

Captan results in increased expression of GPR17 mRNA

NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966

G

glutathione peroxidase 3

increases expression

Captan results in increased expression of GPX3 mRNA

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 4

increases expression

Captan results in increased expression of GPX4 mRNA

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

glycogen synthase kinase 3 beta

multiple interactions

[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione-disulfide reductase

increases expression

Captan results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 2

increases expression

Captan results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 5

increases expression

Captan results in increased expression of GSTA1 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 2

increases expression

Captan results in increased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase, mu 5

increases expression

Captan results in increased expression of GSTM3 mRNA

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase pi 1

multiple interactions
increases expression
decreases activity

hexylglutathione inhibits the reaction [Captan results in decreased activity of GSTP1 protein]
Captan results in increased expression of GSTP1 mRNA

PMID:8678907 PMID:31558096

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glucoside xylosyltransferase 1

increases expression

Captan results in increased expression of GXYLT1 mRNA

NCBI chr 7:124,400,896...124,434,682
Ensembl chr 7:124,400,896...124,434,699

G

H2A.Z variant histone 2

decreases expression

Captan results in decreased expression of H2AZ2 mRNA

NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144

G

H3 clustered histone 1

decreases expression

Captan results in decreased expression of H3C1 mRNA

NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856

G

histone acetyltransferase 1

increases expression

Captan results in increased expression of HAT1 mRNA

NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517

G

histone deacetylase 1

increases expression

Captan results in increased expression of HDAC1 mRNA

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

G

heme binding protein 1

increases expression

Captan results in increased expression of HEBP1 mRNA

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

hes family bHLH transcription factor 1

decreases expression

Captan results in decreased expression of HES1 mRNA

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hepatocyte growth factor

increases expression

Captan results in increased expression of HGF mRNA

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

Holliday junction recognition protein

increases expression

Captan results in increased expression of HJURP mRNA

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

multiple interactions
decreases expression

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA
Captan results in decreased expression of HMGCS2 mRNA

PMID:31558096 PMID:32745781

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression

Captan results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein H1

decreases expression

Captan results in decreased expression of HNRNPH1 mRNA

NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846

G

hook microtubule-tethering protein 2

increases expression

Captan results in increased expression of HOOK2 mRNA

NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181

G

hydroxysteroid (17-beta) dehydrogenase 10

decreases expression

Captan results in decreased expression of HSD17B10 mRNA

NCBI chr X:21,089,142...21,091,603
Ensembl chr X:21,089,122...21,109,488

G

hydroxysteroid (17-beta) dehydrogenase 11

increases expression

Captan results in increased expression of HSD17B11 mRNA

NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161

G

hydroxysteroid (17-beta) dehydrogenase 6

increases expression

Captan results in increased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

heat shock protein 90 alpha family class A member 1

increases expression

Captan results in increased expression of HSP90AA1 mRNA

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 beta family member 1

decreases expression

Captan results in decreased expression of HSP90B1 mRNA

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 1B

increases expression

Captan results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 5

increases expression

Captan results in increased expression of HSPA5 protein

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family B (small) member 1

decreases expression

Captan results in decreased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

heat shock protein family B (small) member 6

decreases expression

Captan results in decreased expression of HSPB6 mRNA

NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071

G

heat shock protein family D (Hsp60) member 1

decreases expression

Captan results in decreased expression of HSPD1 mRNA

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

HtrA serine peptidase 1

decreases expression

Captan results in decreased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

inhibitor of DNA binding 4

decreases expression

Captan results in decreased expression of ID4 mRNA

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

Captan results in decreased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

interferon induced transmembrane protein 2

decreases expression

Captan results in decreased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

decreases expression

Captan results in decreased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

insulin-like growth factor 1

decreases expression

Captan results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

decreases expression

Captan results in decreased expression of IGF1R mRNA

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor binding protein 3

decreases expression

Captan results in decreased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 6

decreases expression

Captan results in decreased expression of IGFBP6 mRNA

NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966

G

interleukin 1 beta

increases secretion

Captan results in increased secretion of IL1B protein

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 1

decreases expression

Captan results in decreased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 6

increases expression

Captan results in increased expression of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

insulin 1

multiple interactions

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of INS1 protein

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin induced gene 1

increases expression

Captan results in increased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

IQ motif containing GTPase activating protein 1

increases expression

Captan results in increased expression of IQGAP1 mRNA

NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755

G

interferon regulatory factor 6

decreases expression

Captan results in decreased expression of IRF6 mRNA

NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386

G

integrin subunit alpha E

decreases expression

Captan results in decreased expression of ITGAE mRNA

NCBI chr10:57,704,813...57,764,093
Ensembl chr10:57,591,753...57,764,093
Ensembl chr10:57,591,753...57,764,093

G

iodotyrosine deiodinase

increases expression

Captan results in increased expression of IYD mRNA

NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

Captan results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

lysyl-tRNA synthetase 1

decreases expression

Captan results in decreased expression of KARS1 mRNA

NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632

G

lysine acetyltransferase 2A

decreases expression

Captan results in decreased expression of KAT2A mRNA

NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166

G

potassium two pore domain channel subfamily K member 1

decreases expression

Captan results in decreased expression of KCNK1 mRNA

NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724

G

kinesin family member 23

decreases expression

Captan results in decreased expression of KIF23 mRNA

NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072

G

KLF transcription factor 2

decreases expression

Captan results in decreased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KLF transcription factor 4

increases expression

Captan results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

kelch-like family member 21

decreases expression

Captan results in decreased expression of KLHL21 mRNA

NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545

G

kelch-like family member 24

decreases expression

Captan results in decreased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

kelch-like family member 9

decreases expression

Captan results in decreased expression of KLHL9 mRNA

NCBI chr 5:103,333,747...103,337,931

G

keratin 7

decreases expression

Captan results in decreased expression of KRT7 mRNA

NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052

G

keratin 8

increases expression

Captan results in increased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

L1 cell adhesion molecule

decreases expression

Captan results in decreased expression of L1CAM mRNA

NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857

G

laminin subunit alpha 2

decreases expression

Captan results in decreased expression of LAMA2 mRNA

NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530

G

lysosomal-associated membrane protein 1

increases expression

Captan results in increased expression of LAMP1 mRNA

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

G

low density lipoprotein receptor

increases expression

Captan results in increased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

luteinizing hormone/choriogonadotropin receptor

decreases expression

Captan results in decreased expression of LHCGR protein

NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521

G

LHFPL tetraspan subfamily member 6

decreases expression

Captan results in decreased expression of LHFPL6 mRNA

NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443

G

lipase A, lysosomal acid type

increases expression

Captan results in increased expression of LIPA mRNA

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

lipin 1

decreases expression

Captan results in decreased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

lecithin retinol acyltransferase

decreases expression

Captan results in decreased expression of LRAT mRNA

NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619

G

leucine rich repeat containing 41

decreases expression

Captan results in decreased expression of LRRC41 mRNA

NCBI chr 5:129,554,547...129,575,450
Ensembl chr 5:129,554,547...129,575,449

G

lymphotoxin beta receptor

increases expression

Captan results in increased expression of LTBR mRNA

NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539

G

lumican

decreases expression

Captan results in decreased expression of LUM mRNA

NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793

G

lysozyme 2

decreases expression

Captan results in decreased expression of LYZ2 mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

MAF bZIP transcription factor F

increases expression

Captan results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

monoamine oxidase A

increases expression

Captan results in increased expression of MAOA mRNA

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

mitogen-activated protein kinase kinase kinase kinase 4

decreases expression

Captan results in decreased expression of MAP4K4 mRNA

NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698

G

mitogen-activated protein kinase 1 interacting protein 1-like

increases expression

Captan results in increased expression of MAPK1IP1L mRNA

NCBI chr15:20,545,043...20,571,466
Ensembl chr15:20,545,059...20,569,674

G

mitogen activated protein kinase 3

increases expression

Captan results in increased expression of MAPK3 mRNA

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

increases phosphorylation

Captan results in increased phosphorylation of MAPK8 protein

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

muscleblind-like splicing regulator 2

increases expression

Captan results in increased expression of MBNL2 mRNA

NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937

G

minichromosome maintenance complex component 7

decreases expression

Captan results in decreased expression of MCM7 mRNA

NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063

G

malic enzyme 1

increases expression

Captan results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

Meis homeobox 2

increases expression

Captan results in increased expression of MEIS2 mRNA

NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696

G

major facilitator superfamily domain containing 10

decreases expression

Captan results in decreased expression of MFSD10 mRNA

NCBI chr14:76,103,762...76,107,385
Ensembl chr14:76,103,815...76,107,377

G

malectin

increases expression

Captan results in increased expression of MLEC mRNA

NCBI chr12:41,458,234...41,468,710
Ensembl chr12:41,458,231...41,468,708

G

MNAT1 component of CDK activating kinase

decreases expression

Captan results in decreased expression of MNAT1 mRNA

NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744

G

MOB kinase activator 1A

decreases expression

Captan results in decreased expression of MOB1A mRNA

NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561

G

mitochondrial ribosomal protein S2

decreases expression

Captan results in decreased expression of MRPS2 mRNA

NCBI chr 3:11,803,044...11,806,341
Ensembl chr 3:11,801,310...11,806,313

G

metastasis associated 1

decreases expression

Captan results in decreased expression of MTA1 mRNA

NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

increases expression

Captan results in increased expression of MTHFD1L mRNA

NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905

G

major vault protein

increases expression

Captan results in increased expression of MVP mRNA

NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380

G

MYC proto-oncogene, bHLH transcription factor

multiple interactions

[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

MYC binding protein 2

decreases expression

Captan results in decreased expression of MYCBP2 mRNA

NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498

G

myosin light chain 9

decreases expression

Captan results in decreased expression of MYL9 mRNA

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

G

myosin light chain kinase

decreases expression

Captan results in decreased expression of MYLK mRNA

NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261

G

NADH:ubiquinone oxidoreductase subunit B10

increases expression

Captan results in increased expression of NDUFB10 mRNA

NCBI chr10:13,749,273...13,751,434
Ensembl chr10:13,749,275...13,751,442

G

NADH:ubiquinone oxidoreductase core subunit S7

decreases expression

Captan results in decreased expression of NDUFS7 mRNA

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

G

NADH:ubiquinone oxidoreductase core subunit V2

decreases expression

Captan results in decreased expression of NDUFV2 mRNA

NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713

G

NADH:ubiquinone oxidoreductase subunit V3

decreases expression

Captan results in decreased expression of NDUFV3 mRNA

NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074

G

neuroepithelial cell transforming 1

increases expression

Captan results in increased expression of NET1 mRNA

NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441

G

nuclear factor, interleukin 3 regulated

decreases expression

Captan results in decreased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NFKB inhibitor beta

increases expression

Captan results in increased expression of NFKBIB mRNA

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

NHERF family PDZ scaffold protein 1

increases expression

Captan results in increased expression of NHERF1 mRNA

NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598

G

NME/NM23 nucleoside diphosphate kinase 1

decreases expression

Captan results in decreased expression of NME1 mRNA

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

G

nitric oxide synthase interacting protein

decreases expression

Captan results in decreased expression of NOSIP mRNA

NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650

G

notch receptor 1

decreases expression

Captan results in decreased expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

NAD(P)H quinone dehydrogenase 1

increases expression

Captan results in increased expression of NQO1 mRNA

PMID:31558096 PMID:35395341

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
increases expression

NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram]
Captan results in increased expression of NR1I3 mRNA

PMID:29950287 PMID:31558096

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nebulin-related anchoring protein

increases expression

Captan results in increased expression of NRAP mRNA

NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693

G

nucleobindin 2

decreases expression

Captan results in decreased expression of NUCB2 mRNA

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

NudC domain containing 3

decreases expression

Captan results in decreased expression of NUDCD3 mRNA

NCBI chr14:80,976,330...81,059,183
Ensembl chr14:80,976,328...81,058,962

G

nucleoporin 37

decreases expression

Captan results in decreased expression of NUP37 mRNA

NCBI chr 7:22,556,544...22,609,622
Ensembl chr 7:22,573,764...22,609,616

G

nucleoporin 85

decreases expression

Captan results in decreased expression of NUP85 mRNA

NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043

G

2'-5'-oligoadenylate synthetase-like

increases expression

Captan results in increased expression of OASL1 mRNA

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

G

oxidative stress induced growth inhibitor 1

increases expression

Captan results in increased expression of OSGIN1 mRNA

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

orthodenticle homeobox 2

multiple interactions

Captan promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of OTX2 mRNA]

NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416

G

3-oxoacid CoA transferase 1

increases expression

Captan results in increased expression of OXCT1 mRNA

NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714

G

prolyl 3-hydroxylase 3

decreases expression

Captan results in decreased expression of P3H3 mRNA

NCBI chr 4:157,646,242...157,662,035
Ensembl chr 4:157,646,243...157,662,035

G

prolyl 4-hydroxylase subunit beta

increases expression

Captan results in increased expression of P4HB mRNA

NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3

decreases expression

Captan results in decreased expression of PAFAH1B3 mRNA

NCBI chr 1:80,881,263...80,883,789
Ensembl chr 1:80,881,309...80,883,893

G

p21 (RAC1) activated kinase 4

increases expression

Captan results in increased expression of PAK4 mRNA

NCBI chr 1:83,849,904...83,889,188
Ensembl chr 1:83,849,904...83,859,413

G

Parkinsonism associated deglycase

decreases activity

Captan results in decreased activity of PARK7 protein

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

G

polysaccharide biosynthesis domain containing 1

increases expression

Captan results in increased expression of PBDC1 mRNA

NCBI chr X:70,154,106...70,197,827
Ensembl chr X:70,154,106...70,184,552

G

platelet derived growth factor receptor beta

multiple interactions

[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

protein disulfide isomerase family A, member 5

decreases expression

Captan results in decreased expression of PDIA5 mRNA

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

pyruvate dehydrogenase kinase 4

affects expression

Captan affects the expression of PDK4 mRNA

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

phosphofructokinase, liver type

increases expression

Captan results in increased expression of PFKL mRNA

NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315

G

profilin 1

increases expression

Captan results in increased expression of PFN1 mRNA

NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631

G

peptidoglycan recognition protein 1

decreases expression

Captan results in decreased expression of PGLYRP1 mRNA

NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001

G

phosphoglucomutase 2

increases expression

Captan results in increased expression of PGM2 mRNA

NCBI chr14:44,166,314...44,199,828
Ensembl chr14:44,164,425...44,199,967

G

progesterone receptor membrane component 1

increases expression

Captan results in increased expression of PGRMC1 mRNA

NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

increases expression

Captan results in increased expression of PIK3C2B mRNA

NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

decreases expression

Captan results in decreased expression of PIK3CG mRNA

NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043

G

plasminogen activator, urokinase

decreases expression

Captan results in decreased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

polynucleotide kinase 3'-phosphatase

increases expression

Captan results in increased expression of PNKP mRNA

NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920

G

RNA polymerase I and III subunit D

increases expression

Captan results in increased expression of POLR1D mRNA

NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624

G

RNA polymerase II subunit C

decreases expression

Captan results in decreased expression of POLR2C mRNA

NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945

G

RNA polymerase III subunit B

decreases expression

Captan results in decreased expression of POLR3B mRNA

NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598

G

cytochrome p450 oxidoreductase

increases expression

Captan results in increased expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

PPARG coactivator 1 alpha

decreases expression

Captan results in decreased expression of PPARGC1A mRNA

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

peptidylprolyl isomerase B

decreases expression

Captan results in decreased expression of PPIB mRNA

NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

decreases expression

Captan results in decreased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein phosphatase 1, regulatory subunit 13B

decreases expression

Captan results in decreased expression of PPP1R13B mRNA

NCBI chr 6:130,890,682...130,963,845
Ensembl chr 6:130,890,679...130,963,330

G

peroxiredoxin 1

increases expression

Captan results in increased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

protein kinase AMP-activated non-catalytic subunit beta 1

decreases expression

Captan results in decreased expression of PRKAB1 mRNA

NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661

G

protein kinase AMP-activated non-catalytic subunit gamma 2

decreases expression

Captan results in decreased expression of PRKAG2 mRNA

NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142

G

protein kinase C, delta

increases expression

Captan results in increased expression of PRKCD mRNA

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

G

protein kinase C, eta

decreases expression

Captan results in decreased expression of PRKCH mRNA

NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654

G

protein kinase cGMP-dependent 1

decreases expression

Captan results in decreased expression of PRKG1 mRNA

NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080

G

proteasome 26S subunit, ATPase 4

increases expression

Captan results in increased expression of PSMC4 mRNA

NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494

G

proteasome 26S subunit, non-ATPase 12

decreases expression

Captan results in decreased expression of PSMD12 mRNA

NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287

G

proteasome 26S subunit, non-ATPase 14

increases expression

Captan results in increased expression of PSMD14 mRNA

NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076

G

proteasome 26S subunit, non-ATPase 8

increases expression

Captan results in increased expression of PSMD8 mRNA

NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209

G

prostaglandin E receptor 4

increases expression

Captan results in increased expression of PTGER4 mRNA

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

G

protein tyrosine kinase 2 beta

multiple interactions

[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

G

protein tyrosine phosphatase, receptor type, K

decreases expression

Captan results in decreased expression of PTPRK mRNA

NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605

G

PWP1 homolog, endonuclein

decreases expression

Captan results in decreased expression of PWP1 mRNA

NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731

G

peroxisomal membrane protein 2

decreases expression

Captan results in decreased expression of PXMP2 mRNA

NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557

G

quinoid dihydropteridine reductase

increases expression

Captan results in increased expression of QDPR mRNA

NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854

G

RAB11a, member RAS oncogene family

increases expression

Captan results in increased expression of RAB11A mRNA

NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525

G

RAB31, member RAS oncogene family

increases expression

Captan results in increased expression of RAB31 mRNA

NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253

G

Rac family small GTPase 1

increases expression

Captan results in increased expression of RAC1 mRNA

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

G

RAS like proto-oncogene B

increases expression

Captan results in increased expression of RALB mRNA

NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202

G

Rap1 GTPase-activating protein

decreases expression

Captan results in decreased expression of RAP1GAP mRNA

NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253

G

RB transcriptional corepressor 1

increases expression

Captan results in increased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RNA binding motif protein 6

increases expression

Captan results in increased expression of RBM6 mRNA

NCBI chr 8:108,452,687...108,552,783
Ensembl chr 8:108,452,687...108,552,771

G

regenerating family member 1 alpha

decreases expression

Captan results in decreased expression of REG1 mRNA

NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570

G

RELA proto-oncogene, NF-kB subunit

decreases expression
increases expression

Captan results in decreased expression of RELA mRNA
Captan results in increased expression of RELA protein

PMID:31558096 PMID:34303901

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

decreases expression

Captan results in decreased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

decreases expression

Captan results in decreased expression of RFNG mRNA

NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345

G

regulator of G-protein signaling 2

decreases expression

Captan results in decreased expression of RGS2 mRNA

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

regulating synaptic membrane exocytosis 1

decreases expression

Captan results in decreased expression of RIMS1 mRNA

NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631

G

ribonuclease H2, subunit A

decreases expression

Captan results in decreased expression of RNASEH2A mRNA

NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041

G

ring finger protein 125

decreases expression

Captan results in decreased expression of RNF125 mRNA

NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983

G

ribose 5-phosphate isomerase A

decreases expression

Captan results in decreased expression of RPIA mRNA

NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355

G

ribosomal protein lateral stalk subunit P0

increases expression

Captan results in increased expression of RPLP0 mRNA

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

G

Ras-related GTP binding A

decreases expression

Captan results in decreased expression of RRAGA mRNA

NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510

G

RT1 class II, locus Ba

decreases expression

Captan results in decreased expression of H2-AA mRNA

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

RuvB-like AAA ATPase 1

increases expression

Captan results in increased expression of RUVBL1 mRNA

NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384

G

S100 calcium binding protein A6

increases expression

Captan results in increased expression of S100A6 mRNA

NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180

G

spermidine/spermine N1-acetyl transferase 1

increases expression

Captan results in increased expression of SAT1 mRNA

NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813

G

secretogranin II

decreases expression

Captan results in decreased expression of SCG2 mRNA

NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097

G

sterol carrier protein 2

increases expression

Captan results in increased expression of SCP2 mRNA

NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287

G

SEL1L adaptor subunit of SYVN1 ubiquitin ligase

decreases expression

Captan results in decreased expression of SEL1L mRNA

NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648

G

serpin family E member 1

multiple interactions

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

serum/glucocorticoid regulated kinase 2

increases expression

Captan results in increased expression of SGK2 mRNA

NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480

G

SH3 domain containing GRB2 like 2, endophilin A1

increases expression

Captan results in increased expression of SH3GL2 mRNA

NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843

G

solute carrier family 11 member 2

increases expression

Captan results in increased expression of SLC11A2 mRNA

NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145

G

solute carrier family 16 member 2

multiple interactions

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA

NCBI chr X:68,725,365...68,848,572
Ensembl chr X:68,723,261...68,848,771

G

solute carrier family 16 member 3

increases expression

Captan results in increased expression of SLC16A3 mRNA

NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562

G

solute carrier family 1 member 3

decreases expression

Captan results in decreased expression of SLC1A3 mRNA

NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605

G

solute carrier family 27 member 1

decreases expression

Captan results in decreased expression of SLC27A1 mRNA

NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 30 member 5

decreases expression

Captan results in decreased expression of SLC30A5 mRNA

NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934

G

solute carrier family 35 member A3

decreases expression

Captan results in decreased expression of SLC35A3 mRNA

NCBI chr 2:204,620,103...204,659,319
Ensembl chr 2:204,579,174...204,659,319

G

solute carrier family 47 member 1

increases expression

Captan results in increased expression of SLC47A1 mRNA

NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637

G

solute carrier family 51 member A

increases expression

Captan results in increased expression of SLC51A mRNA

NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485

G

solute carrier family 6 member 8

increases expression

Captan results in increased expression of SLC6A8 mRNA

NCBI chr X:151,384,675...151,393,979
Ensembl chr X:151,384,675...151,393,979

G

solute carrier family 7 member 11

increases expression

Captan results in increased expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

SMAD family member 1

decreases expression

Captan results in decreased expression of SMAD1 mRNA

NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

decreases expression

Captan results in decreased expression of SMARCD2 mRNA

NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341

G

small nuclear ribonucleoprotein U5 subunit 40

decreases expression

Captan results in decreased expression of SNRNP40 mRNA

NCBI chr 5:142,700,632...142,733,776
Ensembl chr 5:142,700,534...142,733,776

G

small nuclear ribonucleoprotein polypeptide E

decreases expression

Captan results in decreased expression of SNRPE mRNA

NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310

G

sorting nexin 7

increases expression

Captan results in increased expression of SNX7 mRNA

NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:205,842,837...205,927,763

G

suppressor of cytokine signaling 3

increases expression

Captan results in increased expression of SOCS3 mRNA

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

increases expression

Captan results in increased expression of SOD1 mRNA

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

increases expression

Captan results in increased expression of SOD2 mRNA

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

signal peptidase complex subunit 3

decreases expression

Captan results in decreased expression of SPCS3 mRNA

NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746

G

squalene epoxidase

increases expression

Captan results in increased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

sulfide quinone oxidoreductase

increases expression

Captan results in increased expression of SQOR mRNA

NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778

G

SRC proto-oncogene, non-receptor tyrosine kinase

increases expression

Captan results in increased expression of SRC mRNA

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

G

sulfiredoxin 1

increases expression

Captan results in increased expression of SRXN1 mRNA

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

decreases expression

Captan results in decreased expression of ST3GAL2 mRNA

NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

decreases expression

Captan results in decreased expression of ST6GALNAC2 mRNA

NCBI chr10:101,910,220...101,928,412
Ensembl chr10:101,909,971...101,915,008
Ensembl chr10:101,909,971...101,915,008

G

STIP1 homology and U-box containing protein 1

increases expression

Captan results in increased expression of STUB1 mRNA

NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046

G

sulfotransferase family 1B member 1

multiple interactions
increases expression

[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA
Captan results in increased expression of SULT1B1 mRNA

PMID:31558096 PMID:32745781

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

G

transaldolase 1

increases expression

Captan results in increased expression of TALDO1 mRNA

NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974

G

Tax1 binding protein 3

increases expression

Captan results in increased expression of TAX1BP3 mRNA

NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363

G

T-cell leukemia translocation altered

decreases expression

Captan results in decreased expression of TCTA mRNA

NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564

G

thyroid hormone responsive

multiple interactions

[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA]

NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075

G

TP53 induced glycolysis regulatory phosphatase

increases expression

Captan results in increased expression of TIGAR mRNA

NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029

G

transmembrane p24 trafficking protein 10

decreases expression

Captan results in decreased expression of TMED10 mRNA

NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753

G

transmembrane protein 109

decreases expression

Captan results in decreased expression of TMEM109 mRNA

NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215

G

tumor necrosis factor

increases secretion

Captan results in increased secretion of TNF protein

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 13B

decreases expression

Captan results in decreased expression of TNFRSF13B mRNA

NCBI chr10:45,801,860...45,824,932
Ensembl chr10:45,801,860...45,822,987

G

TNFAIP3 interacting protein 1

increases expression

Captan results in increased expression of TNIP1 mRNA

NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625

G

DNA topoisomerase II alpha

decreases activity

Captan results in decreased activity of TOP2A protein

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

torsin family 1, member A

increases expression

Captan results in increased expression of TOR1A mRNA

NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691

G

tumor protein p53 inducible nuclear protein 2

decreases expression

Captan results in decreased expression of TRP53INP2 mRNA

NCBI chr 3:143,881,427...143,890,104
Ensembl chr 3:143,882,021...143,890,097

G

triosephosphate isomerase 1

increases expression

Captan results in increased expression of TPI1 mRNA

NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541

G

TNF receptor-associated protein 1

decreases expression

Captan results in decreased expression of TRAP1 mRNA

NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981

G

tripartite motif-containing 28

decreases expression

Captan results in decreased expression of TRIM28 mRNA

NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380

G

TSC complex subunit 2

decreases expression

Captan results in decreased expression of TSC2 mRNA

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

G

TSC22 domain family, member 1

affects response to substance

TSC22D1 gene SNP affects the susceptibility to Captan

NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958

G

tumor susceptibility 101

increases expression

Captan results in increased expression of TSG101 mRNA

NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554

G

tsukushi, small leucine rich proteoglycan

increases expression

Captan results in increased expression of TSKU mRNA

NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588

G

tetratricopeptide repeat domain 17

increases expression

Captan results in increased expression of TTC17 mRNA

NCBI chr 3:80,263,488...80,374,137
Ensembl chr 3:80,263,495...80,373,812

G

tubulin, alpha 4A

increases expression

Captan results in increased expression of TUBA4A mRNA

NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918

G

tubulin, beta 2A class IIa

increases expression

Captan results in increased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

tubulin, beta 6 class V

decreases expression

Captan results in decreased expression of TUBB6 mRNA

NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418

G

thioredoxin reductase 1

increases expression

Captan results in increased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

UDP-glucose 6-dehydrogenase

increases expression

Captan results in increased expression of UGDH mRNA

NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354

G

UDP glucuronosyltransferase family 1 member A5

increases expression

Captan results in increased expression of UGT1A5 mRNA

NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

vesicle amine transport 1

increases expression

Captan results in increased expression of VAT1 mRNA

NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224

G

vimentin

decreases expression

Captan results in decreased expression of VIM mRNA

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

vacuolar protein sorting 4 homolog A

increases expression

Captan results in increased expression of VPS4A mRNA

NCBI chr19:34,934,999...34,948,888
Ensembl chr19:34,934,961...34,948,887

G

WD repeat domain 3

decreases expression

Captan results in decreased expression of WDR3 mRNA

NCBI chr 2:187,505,816...187,528,432
Ensembl chr 2:187,505,816...187,528,432

G

WAS/WASL interacting protein family, member 2

increases expression

Captan results in increased expression of WIPF2 mRNA

NCBI chr10:83,821,067...83,861,634
Ensembl chr10:83,821,068...83,857,028

G

X-box binding protein 1

decreases expression

Captan results in decreased expression of XBP1 mRNA

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

Yes1 associated transcriptional regulator

decreases expression

Captan results in decreased expression of YAP1 mRNA

NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010

G

tyrosyl-tRNA synthetase 2

decreases expression

Captan results in decreased expression of YARS2 mRNA

NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125

G

YKT6 v-SNARE homolog

increases expression

Captan results in increased expression of YKT6 mRNA

NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385

G

YTH N6-methyladenosine RNA binding protein F1

decreases expression

Captan results in decreased expression of YTHDF1 mRNA

NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

increases expression

Captan results in increased expression of YWHAZ mRNA

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

G

Z-DNA binding protein 1

decreases expression

Captan results in decreased expression of ZBP1 mRNA

NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870

G

zinc finger protein 395

decreases expression

Captan results in decreased expression of ZFP395 mRNA

NCBI chr15:39,581,603...39,621,911
Ensembl chr15:39,608,080...39,619,950

G

zymogen granule protein 16

decreases expression

Captan results in decreased expression of ZG16 mRNA

NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079

G

zinc finger, HIT-type containing 6

increases expression

Captan results in increased expression of ZNHIT6 mRNA

NCBI chr 2:234,486,686...234,517,952
Ensembl chr 2:234,486,704...234,517,960

chaetoglobosin A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

increases phosphorylation
multiple interactions

chaetoglobosins results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

gap junction protein, alpha 1

multiple interactions

chaetoglobosins inhibits the reaction [Dieldrin results in decreased phosphorylation of GJA1 protein]; chaetoglobosins inhibits the reaction [Hexachlorocyclohexane results in decreased phosphorylation of GJA1 protein]

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

glycogen synthase kinase 3 beta

increases phosphorylation
multiple interactions

chaetoglobosins results in increased phosphorylation of GSK3B protein
wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

interferon beta 1

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interleukin 1 beta

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interferon regulatory factor 7

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of IRF7 mRNA]

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

chaetoglobosins results in increased phosphorylation of MAPK1 protein
chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]

PMID:18040759 PMID:33285210

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases phosphorylation
multiple interactions

chaetoglobosins results in increased phosphorylation of MAPK3 protein
chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]

PMID:18040759 PMID:33285210

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

MYD88, innate immune signal transduction adaptor

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

nitric oxide synthase 2

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

prostaglandin-endoperoxide synthase 2

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

Raf-1 proto-oncogene, serine/threonine kinase

decreases phosphorylation

chaetoglobosins results in decreased phosphorylation of RAF1 protein

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

toll-like receptor 4

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

tumor necrosis factor

multiple interactions

chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; chaetoglobosins results in increased expression of and results in increased secretion of TNF protein

PMID:28535995 PMID:33285210

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

chlorisondamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

chromogranin A

multiple interactions

Chlorisondamine inhibits the reaction [Nicotine results in increased activity of CHGA promoter]; Chlorisondamine inhibits the reaction [Reserpine results in increased activity of CHGA promoter]

NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398

G

neuropeptide Y

multiple interactions

Chlorisondamine inhibits the reaction [Reserpine results in increased expression of NPY mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of NPY mRNA]

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

G

phenylethanolamine-N-methyltransferase

multiple interactions

Chlorisondamine inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]

NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556

G

renin

multiple interactions

Chlorisondamine inhibits the reaction [Yohimbine results in increased expression of REN protein]

NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489

G

tyrosine hydroxylase

multiple interactions
increases expression

Chlorisondamine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of TH mRNA]
Chlorisondamine results in increased expression of TH mRNA

NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767

chlorthalidone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

fibroblast growth factor receptor 3

decreases expression

Chlorthalidone results in decreased expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

neuropilin 2

decreases expression

Chlorthalidone results in decreased expression of NRP2 mRNA

NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958

G

renin

increases expression
increases activity

Chlorthalidone results in increased expression of REN protein modified form
Chlorthalidone results in increased activity of REN protein

PMID:796642 PMID:1116335 PMID:3319646

NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489

G

transforming growth factor, beta 3

decreases expression

Chlorthalidone results in decreased expression of TGFB3 mRNA

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

G

vascular endothelial growth factor C

decreases expression
increases expression

Chlorthalidone results in decreased expression of VEGFC mRNA; Chlorthalidone results in decreased expression of VEGFC protein
Chlorthalidone results in increased expression of VEGFC protein

NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848

cytochalasin B

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cytochalasin B results in increased expression of BAX protein]

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

multiple interactions
decreases expression

1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cytochalasin B results in decreased expression of BCL2 protein]

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

complement C5

multiple interactions

[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Cytochalasin B co-treated with C5 protein] results in increased secretion of EPO protein; Dexamethasone analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased secretion of EPO protein]; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased secretion of EPO protein]

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

caspase 3

increases cleavage

Cytochalasin B results in increased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases cleavage

Cytochalasin B results in increased cleavage of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions

Cytochalasin B inhibits the reaction [Dehydroascorbic Acid results in increased expression of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cyclin B1

decreases expression

Cytochalasin B results in decreased expression of CCNB1 protein

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin-dependent kinase 1

decreases expression

Cytochalasin B results in decreased expression of CDK1 protein

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase inhibitor 1A

increases expression

Cytochalasin B results in increased expression of CDKN1A protein

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression

Cytochalasin B results in increased expression of CDKN1B protein

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

colony stimulating factor 2

multiple interactions

Cytochalasin B inhibits the reaction [kaempferol results in increased secretion of CSF2 protein]; Cytochalasin B inhibits the reaction [Quercetin results in increased secretion of CSF2 protein]

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

epidermal growth factor receptor

multiple interactions

Cytochalasin B inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein]

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

elastase, neutrophil expressed

multiple interactions

[Cytochalasin B co-treated with N-Formylmethionine Leucyl-Phenylalanine] results in increased secretion of ELANE protein; pirinixic acid analog inhibits the reaction [[Cytochalasin B co-treated with N-Formylmethionine Leucyl-Phenylalanine] results in increased secretion of ELANE protein]

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

G

erythropoietin

multiple interactions

[Cytochalasin B co-treated with C5 protein] results in increased secretion of EPO protein; [Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein; Dexamethasone analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased secretion of EPO protein]; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased secretion of EPO protein]; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein]

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

G

fission, mitochondrial 1

increases expression

Cytochalasin B results in increased expression of FIS1 protein

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

glucuronidase, beta

multiple interactions

[Platelet Activating Factor co-treated with Cytochalasin B] results in increased secretion of GUSB protein; IMMLG5521 inhibits the reaction [[Platelet Activating Factor co-treated with Cytochalasin B] results in increased secretion of GUSB protein]

NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905

G

heat shock protein family A (Hsp70) member 5

increases expression

Cytochalasin B results in increased expression of HSPA5 protein

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interleukin 1 beta

multiple interactions

Cytochalasin B inhibits the reaction [[Alum Compounds co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form]; Cytochalasin B inhibits the reaction [Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; Cytochalasin B inhibits the reaction [Asbestos, Serpentine promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]

PMID:9698594 PMID:17404311

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 5

multiple interactions

[Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein]

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

insulin 1

multiple interactions

Cytochalasin B inhibits the reaction [INS1 protein results in increased uptake of Glucose]; Cytochalasin B inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]
Cytochalasin B inhibits the reaction [INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]]

PMID:15172182 PMID:25543134

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

lipoprotein lipase

decreases activity

Cytochalasin B results in decreased activity of LPL protein

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

mitogen activated protein kinase 1

multiple interactions

[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK1 protein; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK1 protein]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK3 protein; resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK3 protein]

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

solute carrier family 2 member 1

affects folding
affects binding
multiple interactions

Cytochalasin B affects the folding of SLC2A1 protein
Cytochalasin B binds to SLC2A1 protein
Cytochalasin B binds to and results in decreased activity of SLC2A1 protein; Cytochalasin B inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]
oxophenylarsine inhibits the reaction [Cytochalasin B binds to SLC2A1 protein]

PMID:8457197 PMID:19686715 PMID:22363641 PMID:27078104

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 2

multiple interactions
affects binding

Cytochalasin B inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]
Cytochalasin B binds to SLC2A2 protein
Cytochalasin B inhibits the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]; Mercuric Chloride inhibits the reaction [Cytochalasin B binds to SLC2A2 protein]

PMID:8457197 PMID:10825458

NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 2 member 3

multiple interactions

Cytochalasin B inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]

NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472

G

superoxide dismutase 2

multiple interactions

Cytochalasin B inhibits the reaction [Dehydroascorbic Acid results in increased expression of SOD2 protein]

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

tumor protein p53

increases expression

Cytochalasin B results in increased expression of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

cytochalasin D

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

multiple interactions
increases phosphorylation

EGF protein inhibits the reaction [Cytochalasin D results in increased phosphorylation of ABL1 protein]

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

G

actin alpha 2, smooth muscle

multiple interactions
increases expression

Cytochalasin D inhibits the reaction [Oxygen results in increased expression of ACTA2 mRNA]; Cytochalasin D inhibits the reaction [Oxygen results in increased expression of ACTA2 protein]
Cytochalasin D results in increased expression of ACTA2 mRNA

PMID:11035001 PMID:23517783

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin, gamma 1

multiple interactions

Cytochalasin D inhibits the reaction [UPF1 protein binds to ACTG1 protein]; Cytochalasin D inhibits the reaction [UPF2 protein binds to ACTG1 protein]; Cytochalasin D inhibits the reaction [UPF3B protein binds to ACTG1 protein]

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232

G

cadherin 1

multiple interactions
increases expression

[Cytochalasin D results in increased expression of CDH1 protein] which results in decreased activity of RHOA protein; RHOA protein mutant form affects the reaction [Cytochalasin D results in increased expression of CDH1 protein]
Cytochalasin D results in increased expression of CDH1 mRNA; Cytochalasin D results in increased expression of CDH1 protein

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

collagen type I alpha 1 chain

multiple interactions

Cytochalasin D inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

multiple interactions

Cytochalasin D inhibits the reaction [Oxygen results in increased expression of COL1A2 mRNA]

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

colony stimulating factor 2

multiple interactions

Cytochalasin D inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Cytochalasin D inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein]

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

C-X-C motif chemokine receptor 1

multiple interactions

Cytochalasin D promotes the reaction [CXCL8 protein results in decreased expression of CXCR1 protein]

NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084

G

C-X-C motif chemokine receptor 2

multiple interactions

Cytochalasin D promotes the reaction [CXCL8 protein results in decreased expression of CXCR2 protein]

NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425

G

epidermal growth factor

multiple interactions

EGF protein inhibits the reaction [Cytochalasin D results in increased phosphorylation of ABL1 protein]

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

multiple interactions

Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein]

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

coagulation factor III, tissue factor

multiple interactions

Cytochalasin D inhibits the reaction [Particulate Matter results in increased expression of F3 mRNA]

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

glutathione peroxidase 1

affects localization

Cytochalasin D affects the localization of GPX1 mRNA mutant form

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

intercellular adhesion molecule 1

multiple interactions

Cytochalasin D inhibits the reaction [TNF protein affects the localization of ICAM1 protein]

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

interferon gamma

multiple interactions

Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

inhibitor of nuclear factor kappa B kinase subunit beta

increases phosphorylation
multiple interactions

Cytochalasin D results in increased phosphorylation of IKBKB protein
Cytochalasin D results in decreased localization of [IKBKB protein binds to NFKBIA protein]

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 1 alpha

multiple interactions

Cytochalasin D inhibits the reaction [Quartz results in increased import of IL1A protein]; Cytochalasin D promotes the reaction [Quartz results in increased secretion of IL1A protein]

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

multiple interactions

Cytochalasin D inhibits the reaction [[Lipopolysaccharides co-treated with Silicon Dioxide] results in increased cleavage of and results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased cleavage of and results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [Nanotubes, Carbon results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [titanium dioxide results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]

PMID:12799187 PMID:18403674 PMID:18604214 PMID:24158569 PMID:24760326 More...

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

decreases chemical synthesis
increases stability

Cytochalasin D results in decreased chemical synthesis of IL6 protein
Cytochalasin D results in increased stability of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

influenza virus NS1A binding protein

increases response to substance

IVNS1ABP gene mutant form results in increased susceptibility to Cytochalasin D

NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701

G

lactate dehydrogenase A

multiple interactions

Cytochalasin D inhibits the reaction [Quartz results in increased activity of and results in increased secretion of LDHA protein]

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

matrix metallopeptidase 9

multiple interactions

Cytochalasin D promotes the reaction [TNF results in increased expression of MMP9 mRNA]

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

myocardin related transcription factor A

multiple interactions

Cytochalasin D inhibits the reaction [Oxygen affects the localization of MRTFA protein]

NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418

G

nuclear factor of activated T-cells 4

decreases localization

Cytochalasin D results in decreased localization of NFATC4 protein

NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610

G

NFKB inhibitor alpha

increases phosphorylation
multiple interactions

Cytochalasin D results in increased phosphorylation of NFKBIA protein
Cytochalasin D results in decreased localization of [IKBKB protein binds to NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nitric oxide synthase 2

multiple interactions

Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

purinergic receptor P2X 1

decreases activity

Cytochalasin D results in decreased activity of P2RX1 protein

NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623

G

pancreatic and duodenal homeobox 1

decreases uptake

Cytochalasin D results in decreased uptake of PDX1 protein

NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064

G

plasminogen activator, tissue type

increases expression

Cytochalasin D results in increased expression of PLAT

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

ras homolog family member A

multiple interactions

[Cytochalasin D results in increased expression of CDH1 protein] which results in decreased activity of RHOA protein; RHOA protein mutant form affects the reaction [Cytochalasin D results in increased expression of CDH1 protein]

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

G

retinoschisin 1

decreases secretion

Cytochalasin D results in decreased secretion of RS1 protein

NCBI chr X:33,962,440...33,992,203
Ensembl chr X:33,963,657...33,992,115

G

solute carrier family 31 member 1

multiple interactions

Cytochalasin D inhibits the reaction [Cisplatin results in increased degradation of SLC31A1 protein]

NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228

G

SMAD family member 1

affects localization

Cytochalasin D affects the localization of SMAD1 protein

NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651

G

SMAD family member 2

affects localization

Cytochalasin D affects the localization of SMAD2 protein

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

G

SMAD family member 3

affects localization

Cytochalasin D affects the localization of SMAD3 protein

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

snail family transcriptional repressor 1

affects localization

Cytochalasin D affects the localization of SNAI1 protein

NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969

G

signal transducer and activator of transcription 1

multiple interactions

Cytochalasin D deficiency results in decreased activity of and affects the localization of STAT1 protein

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

signal transducer and activator of transcription 3

multiple interactions

Cytochalasin D deficiency results in decreased activity of and affects the localization of STAT3 protein

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

transgelin

increases expression

Cytochalasin D results in increased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

tumor necrosis factor

multiple interactions

Cytochalasin D inhibits the reaction [TNF protein affects the localization of ICAM1 protein]; Cytochalasin D inhibits the reaction [TNF protein affects the localization of VCAM1 protein]; Cytochalasin D inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; Cytochalasin D promotes the reaction [TNF results in increased expression of MMP9 mRNA]
Cytochalasin D inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Cytochalasin D inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]

PMID:8409756 PMID:12799187 PMID:15034928 PMID:17560598

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

thioredoxin 1

multiple interactions

Cytochalasin D inhibits the reaction [Cadmium Chloride affects the localization of TXN protein]

NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629

G

UPF1, RNA helicase and ATPase

affects localization
multiple interactions

Cytochalasin D affects the localization of UPF1 protein
Cytochalasin D inhibits the reaction [UPF1 protein binds to ACTG1 protein]

NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568

G

UPF2, regulator of nonsense mediated mRNA decay

multiple interactions

Cytochalasin D inhibits the reaction [UPF2 protein binds to ACTG1 protein]

NCBI chr17:72,224,575...72,335,896
Ensembl chr17:72,225,316...72,335,855

G

UPF3B, regulator of nonsense mediated mRNA decay

multiple interactions

Cytochalasin D inhibits the reaction [UPF3B protein binds to ACTG1 protein]

NCBI chr X:116,335,308...116,353,332
Ensembl chr X:116,335,308...116,353,236

G

vascular cell adhesion molecule 1

multiple interactions

Cytochalasin D inhibits the reaction [TNF protein affects the localization of VCAM1 protein]; Cytochalasin D inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

Cytochalasin H

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

protocadherin 10

increases expression

cytochalasin H results in increased expression of PCDH10 mRNA

NCBI chr 2:128,617,212...128,683,354
Ensembl chr 2:128,617,174...128,677,190

G

plasminogen activator, urokinase

decreases expression

cytochalasin H results in decreased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

Dialifor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

decreases activity

dialifor metabolite results in decreased activity of ACHE protein; dialifor results in decreased activity of ACHE protein

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

tumor protein p53

affects activity

dialifor metabolite affects the activity of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

Dihydrocytochalasin B

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

FGR proto-oncogene, Src family tyrosine kinase

multiple interactions

1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of FGR protein]

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

folpet

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

increases expression

folpet results in increased expression of ABCB1A mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 3

increases expression

folpet results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 5

increases expression

folpet results in increased expression of ABCC5 mRNA

NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253

G

ATP binding cassette subfamily F member 1

increases expression

folpet results in increased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

abhydrolase domain containing 6, acylglycerol lipase

increases expression

folpet results in increased expression of ABHD6 mRNA

NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985

G

acetyl-CoA acyltransferase 1A

increases expression

folpet results in increased expression of ACAA1A mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

folpet results in increased expression of ACAA1B mRNA

NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA acetyltransferase 2

increases expression

folpet results in increased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

ACD, shelterin complex subunit and telomerase recruitment factor

decreases expression

folpet results in decreased expression of ACD mRNA

NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461

G

angiotensin I converting enzyme

decreases expression

folpet results in decreased expression of ACE mRNA

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

aconitase 2

increases expression

folpet results in increased expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA oxidase 1

increases expression

folpet results in increased expression of ACOX1 mRNA

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

actin alpha 2, smooth muscle

decreases expression

folpet results in decreased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

adenylate cyclase 6

decreases expression

folpet results in decreased expression of ADCY6 mRNA

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

G

adhesion G protein-coupled receptor L4

decreases expression

folpet results in decreased expression of ELTD1 mRNA

NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225

G

alcohol dehydrogenase 5 (class III), chi polypeptide

increases expression

folpet results in increased expression of ADH5 mRNA

NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591

G

agmatinase

decreases expression

folpet results in decreased expression of AGMAT mRNA

NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276

G

aryl hydrocarbon receptor

increases expression

folpet results in increased expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aldo-keto reductase family 1 member B10

increases expression

folpet results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

5'-aminolevulinate synthase 1

increases expression

folpet results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

aldehyde dehydrogenase 1 family, member A1

increases expression

folpet results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

increases expression

folpet results in increased expression of ALDH2 mRNA

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A2

increases expression

folpet results in increased expression of ALDH3A2 mRNA

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 7 family, member A1

decreases expression

folpet results in decreased expression of ALDH7A1 mRNA

NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193

G

aldolase, fructose-bisphosphate B

increases expression

folpet results in increased expression of ALDOB mRNA

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

aldolase, fructose-bisphosphate C

increases expression

folpet results in increased expression of ALDOA mRNA; folpet results in increased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

arachidonate 5-lipoxygenase activating protein

decreases expression

folpet results in decreased expression of ALOX5AP mRNA

NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986

G

amidohydrolase domain containing 2

increases expression

folpet results in increased expression of AMDHD2 mRNA

NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095

G

adaptor related protein complex 2 subunit mu 1

increases expression

folpet results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

apolipoprotein A1

increases expression

folpet results in increased expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein C3

increases expression

folpet results in increased expression of APOC3 mRNA

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein E

decreases expression

folpet results in decreased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

decreases expression

folpet results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 1

decreases expression

folpet results in decreased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

ADP-ribosylation factor 1

increases expression

folpet results in increased expression of ARF1 mRNA

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

Rho GTPase activating protein 9

decreases expression

folpet results in decreased expression of ARHGAP9 mRNA

NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524

G

AT-rich interaction domain 4B

increases expression

folpet results in increased expression of ARID4B mRNA

NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906

G

ADP-ribosylation factor like GTPase 1

increases expression

folpet results in increased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

aryl hydrocarbon receptor nuclear translocator

decreases expression

folpet results in decreased expression of ARNT mRNA

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

folpet results in increased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

cAMP-regulated phosphoprotein 19

increases expression

folpet results in increased expression of ARPP19 mRNA

NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452

G

arylsulfatase A

increases expression

folpet results in increased expression of ARSA mRNA

NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783

G

autophagy related 3

increases expression

folpet results in increased expression of ATG3 mRNA

NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224

G

ATPase phospholipid transporting 11B (putative)

increases expression

folpet results in increased expression of ATP11B mRNA

NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232

G

ATPase Na+/K+ transporting subunit alpha 1

decreases expression

folpet results in decreased expression of ATP1A1 mRNA

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATP synthase F1 subunit alpha

increases expression

folpet results in increased expression of ATP5F1A mRNA

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATP synthase F1 subunit beta

increases expression

folpet results in increased expression of ATP5F1B mRNA

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase F1 subunit epsilon

increases expression

folpet results in increased expression of ATP5F1E mRNA

NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450

G

ATPase H+ transporting V1 subunit D

increases expression

folpet results in increased expression of ATP6V1D mRNA

NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303

G

axin 1

increases expression

folpet results in increased expression of AXIN1 mRNA

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

G

beta-1,4-galactosyltransferase 1

increases expression

folpet results in increased expression of B4GALT1 mRNA

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

BCL2-associated agonist of cell death

increases expression

folpet results in increased expression of BAD mRNA

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BAF nuclear assembly factor 1

increases expression

folpet results in increased expression of BANF1 mRNA

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

G

BCL2 associated X, apoptosis regulator

multiple interactions

[Sulfur co-treated with folpet co-treated with penconazole] affects the expression of BAX mRNA; [Sulfur co-treated with folpet co-treated with penconazole] results in increased expression of BAX mRNA; [Sulfur co-treated with folpet] affects the expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

decreases expression

folpet results in decreased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCL2, apoptosis regulator

multiple interactions

[Sulfur co-treated with folpet] results in decreased expression of BCL2 mRNA

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

3-hydroxybutyrate dehydrogenase 1

decreases expression

folpet results in decreased expression of BDH1 mRNA

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

beclin 1

increases expression

folpet results in increased expression of BECN1 mRNA

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

biglycan

decreases expression

folpet results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

basic helix-loop-helix family, member e40

increases expression

folpet results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

biogenesis of lysosomal organelles complex-1, subunit 2

increases expression

folpet results in increased expression of BLOC1S2 mRNA

NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653

G

biliverdin reductase A

increases expression

folpet results in increased expression of BLVRA mRNA

NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033

G

bone morphogenetic protein 6

decreases expression

folpet results in decreased expression of BMP6 mRNA

NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365

G

BCL2 interacting protein 3

increases expression

folpet results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

3'(2'), 5'-bisphosphate nucleotidase 1

increases expression

folpet results in increased expression of BPNT1 mRNA

NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503

G

basigin

increases expression

folpet results in increased expression of BSG mRNA

NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387

G

BTG anti-proliferation factor 2

increases expression

folpet results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

complement C1q A chain

decreases expression

folpet results in decreased expression of C1QA mRNA

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

G

complement C1q B chain

decreases expression

folpet results in decreased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

decreases expression

folpet results in decreased expression of C1QC mRNA

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

C2 calcium-dependent domain containing 2

decreases expression

folpet results in decreased expression of C2CD2 mRNA

NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739

G

calcium binding and coiled coil domain 1

decreases expression

folpet results in decreased expression of CALCOCO1 mRNA

NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422

G

calnexin

decreases expression

folpet results in decreased expression of CANX mRNA

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

capping actin protein, gelsolin like

increases expression

folpet results in increased expression of CAPG mRNA

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

carbonic anhydrase 9

increases expression

folpet results in increased expression of CAR9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

CASC3 exon junction complex subunit

decreases expression

folpet results in decreased expression of CASC3 mRNA

NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966

G

caspase 7

increases expression

folpet results in increased expression of CASP7 mRNA

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

catalase

increases expression

folpet results in increased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

decreases expression

folpet results in decreased expression of CAV1 mRNA

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

caveolae associated protein 2

decreases expression

folpet results in decreased expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

G

Cbl proto-oncogene B

increases expression

folpet results in increased expression of CBLB mRNA

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

G

carbonyl reductase 1

increases expression

folpet results in increased expression of CBR1 mRNA

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 3

increases expression

folpet results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

cyclin D2

decreases expression

folpet results in decreased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin E2

increases expression

folpet results in increased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

chaperonin containing TCP1 subunit 6A

decreases expression

folpet results in decreased expression of CCT6A mRNA

NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337

G

Cd48 molecule

decreases expression

folpet results in decreased expression of CD48 mRNA

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

CD74 molecule

decreases expression

folpet results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

cytidine deaminase

increases expression

folpet results in increased expression of CDA mRNA

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

G

cyclin-dependent kinase 19

decreases expression

folpet results in decreased expression of CDK19 mRNA

NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628

G

cyclin-dependent kinase 4

decreases expression

folpet results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 7

increases expression

folpet results in increased expression of CDK7 mRNA

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

cyclin-dependent kinase inhibitor 1A

increases expression

folpet results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

decreases expression

folpet results in decreased expression of CDKN1B mRNA

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

CEA cell adhesion molecule 1

decreases expression

folpet results in decreased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CCAAT/enhancer binding protein beta

increases expression

folpet results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

centromere protein F

decreases expression

folpet results in decreased expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centromere protein I

decreases expression

folpet results in decreased expression of CENPI mRNA

NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657

G

carboxylesterase 2C

increases expression

folpet results in increased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790

G

centrin 2

decreases expression

folpet results in decreased expression of CETN2 mRNA

NCBI chr X:150,769,944...150,774,833
Ensembl chr X:150,769,953...150,774,919

G

centrin 3

increases expression

folpet results in increased expression of CETN3 mRNA

NCBI chr 2:12,089,025...12,101,828
Ensembl chr 2:12,089,226...12,101,828

G

charged multivesicular body protein 6

increases expression

folpet results in increased expression of CHMP6 mRNA

NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640

G

calcium and integrin binding 1

increases expression

folpet results in increased expression of CIB1 mRNA

NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423

G

cell death-inducing DFFA-like effector c

increases expression

folpet results in increased expression of CIDEC mRNA

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

cold inducible RNA binding protein

decreases expression

folpet results in decreased expression of CIRBP mRNA

NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818

G

creatine kinase, M-type

decreases expression

folpet results in decreased expression of CKM mRNA

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

claudin 7

decreases expression

folpet results in decreased expression of CLDN7 mRNA

NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171

G

CAP-GLY domain containing linker protein 3

decreases expression

folpet results in decreased expression of CLIP3 mRNA

NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184

G

calsyntenin 1

decreases expression

folpet results in decreased expression of CLSTN1 mRNA

NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583

G

clathrin, light chain B

increases expression

folpet results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

carnosine dipeptidase 2

increases expression

folpet results in increased expression of CNDP2 mRNA

NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922

G

Cnksr family member 3

decreases expression

folpet results in decreased expression of CNKSR3 mRNA

NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635

G

calponin 1

decreases expression

folpet results in decreased expression of CNN1 mRNA

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

calponin 3

decreases expression

folpet results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

component of oligomeric golgi complex 4

increases expression

folpet results in increased expression of COG4 mRNA

NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796

G

collagen type I alpha 1 chain

decreases expression

folpet results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type IV alpha 1 chain

decreases expression

folpet results in decreased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type IV alpha 2 chain

decreases expression

folpet results in decreased expression of COL4A2 mRNA

NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839

G

collagen type VI alpha 2 chain

decreases expression

folpet results in decreased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen type VI alpha 3 chain

decreases expression

folpet results in decreased expression of COL6A3 mRNA

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

catechol-O-methyltransferase

increases expression