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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:intercalator
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Accession:CHEBI:24853 term browser browse the term
Definition:A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
Synonyms:related_synonym: agente intercalante;   intercalating agent;   intercalating agents;   intercalating ligands;   intercalators


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  CHEBI ontology 19761
    role 19711
      biological role 19711
        aetiopathogenetic role 18963
          genotoxin 17330
            mutagen 17208
              intercalator 3494
                3,6-diamino-10-methylacridinium chloride + 0
                3,6-diamino-10-methylacridinium chloride.HCl + 0
                3,6-diaminoacridine 10
                3,6-diaminoacridine dihydrochloride + 0
                3,6-diaminoacridine monohydrochloride + 0
                ICR-170 0
                acriflavinium chloride 0
                acriflavinium monochloride 0
                benzo[a]pyrene diol epoxide I 3266
                ethidium + 18
                ethidium homodimer 0
                mitomycin + 403
                nogalamycin 0
                propidium + 8
                quinacrine mustard dihydrochloride 0
                saintopin 0
                steffimycin D 0
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