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ONTOLOGY REPORT - ANNOTATIONS


Term:intercalator
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Accession:CHEBI:24853 term browser browse the term
Definition:A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
Synonyms:related_synonym: agente intercalante;   intercalating agent;   intercalating agents;   intercalating ligands;   intercalators


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  CHEBI ontology 19728
    role 19675
      biological role 19673
        aetiopathogenetic role 18781
          genotoxin 16055
            mutagen 15677
              intercalator 3492
                3,6-diamino-10-methylacridinium chloride + 0
                3,6-diamino-10-methylacridinium chloride.HCl + 0
                3,6-diaminoacridine 10
                3,6-diaminoacridine dihydrochloride + 0
                3,6-diaminoacridine monohydrochloride + 0
                ICR-170 0
                acriflavinium chloride 0
                acriflavinium monochloride 0
                benzo[a]pyrene diol epoxide I 3264
                ethidium + 18
                ethidium homodimer 0
                mitomycin + 404
                propidium + 8
                quinacrine mustard dihydrochloride 0
                saintopin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.