CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: insect attractant
Accession: CHEBI:24850
browse the term
Definition: A chemical that attracts insects.
Synonyms: related_synonym: insect attractants
xref: PMID:7044287
G
Pomc
proopiomelanocortin
multiple interactions
EXP
[2,5-dihydro-2,4,5-trimethylthiazoline co-treated with 3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC protein; [3-hexen-1-ol co-treated with 2-hexenal] inhibits the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in decreased expression of POMC protein]; [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC
CTD
PMID:19103229 PMID:21515296
NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664
G
Atf3
activating transcription factor 3
increases expression
ISO
Dodecanol analog results in increased expression of ATF3 mRNA
CTD
PMID:27965148
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631
G
Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression
ISO
Dodecanol analog results in increased expression of DNAJB4 mRNA
CTD
PMID:27965148
NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:241,130,340...241,159,089
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Dodecanol analog results in increased expression of GCLM mRNA
CTD
PMID:27965148
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
G
Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
estragole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD
PMID:29191726
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
G
Casp3
caspase 3
increases expression
EXP
estragole results in increased expression of CASP3 protein modified form
CTD
PMID:29054680
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
G
Ccna2
cyclin A2
increases expression
EXP
estragole results in increased expression of CCNA2 mRNA
CTD
PMID:29054680
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577
G
Ccnb1
cyclin B1
increases expression multiple interactions
EXP ISO
estragole results in increased expression of CCNB1 mRNA flumequine promotes the reaction [estragole results in increased expression of CCNB1 mRNA]
CTD
PMID:29054680 PMID:31029721
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172
G
Ccnd1
cyclin D1
increases expression
EXP
estragole results in increased expression of CCND1 protein
CTD
PMID:29054680
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
G
Ccne1
cyclin E1
increases expression multiple interactions
EXP ISO
estragole results in increased expression of CCNE1 mRNA [flumequine co-treated with estragole] results in increased expression of CCNE1 mRNA
CTD
PMID:29054680 PMID:31029721
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101
G
Chek1
checkpoint kinase 1
increases expression
EXP
estragole results in increased expression of CHEK1 protein
CTD
PMID:29054680
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:36,420,569...36,441,009
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
estragole inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD
PMID:29191726
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases hydroxylation increases response to substance multiple interactions increases expression
ISO
CYP1A2 protein results in increased hydroxylation of estragole CYP1A2 protein results in increased susceptibility to estragole [flumequine co-treated with estragole] results in increased expression of CYP1A2 mRNA estragole results in increased expression of CYP1A2 mRNA
CTD
PMID:19920071 PMID:31029721 PMID:32853702
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases hydroxylation
ISO
CYP2E1 protein results in increased hydroxylation of estragole
CTD
PMID:19920071
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
G
Gsk3b
glycogen synthase kinase 3 beta
increases phosphorylation
EXP
estragole results in increased phosphorylation of GSK3B protein
CTD
PMID:29054680
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646
G
H2ax
H2A.X variant histone
increases expression
EXP
estragole results in increased expression of H2AX protein modified form
CTD
PMID:29054680
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
G
Mapk1
mitogen activated protein kinase 1
increases phosphorylation
EXP
estragole results in increased phosphorylation of MAPK1 protein
CTD
PMID:29054680
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
increases phosphorylation
EXP
estragole results in increased phosphorylation of MAPK3 protein
CTD
PMID:29054680
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
G
Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
EXP
estragole results in increased phosphorylation of MAPK8 protein
CTD
PMID:29054680
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
G
Mapk9
mitogen-activated protein kinase 9
increases phosphorylation
EXP
estragole results in increased phosphorylation of MAPK9 protein
CTD
PMID:29054680
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178
G
Pcna
proliferating cell nuclear antigen
increases expression
EXP
estragole results in increased expression of PCNA protein
CTD
PMID:22576464 PMID:29054680
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995
G
Ppp2ca
protein phosphatase 2 catalytic subunit alpha
increases phosphorylation
EXP
estragole results in increased phosphorylation of PPP2CA protein
CTD
PMID:29054680
NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862
G
Rad51
RAD51 recombinase
increases expression
EXP
estragole results in increased expression of RAD51 protein
CTD
PMID:29054680
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:106,100,381...106,125,035
G
Src
SRC proto-oncogene, non-receptor tyrosine kinase
increases phosphorylation
EXP
estragole results in increased phosphorylation of SRC protein
CTD
PMID:29054680
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476
G
Tnf
tumor necrosis factor
multiple interactions
ISO
[flumequine co-treated with estragole] results in increased expression of TNF mRNA
CTD
PMID:31029721
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
G
Tp53
tumor protein p53
increases phosphorylation
EXP
estragole results in increased phosphorylation of TP53 protein
CTD
PMID:29054680
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
multiple interactions
ISO
[flumequine co-treated with estragole] results in decreased expression of UGT1A1 mRNA
CTD
PMID:31029721
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465
G
Acod1
aconitate decarboxylase 1
affects expression
ISO
methyl salicylate affects the expression of ACOD1 mRNA
CTD
PMID:22302311
NCBI chr15:86,286,531...86,295,803
Ensembl chr15:79,871,827...79,880,529
G
Akr1b1
aldo-keto reductase family 1 member B1
increases expression
ISO
methyl salicylate results in increased expression of AKR1B1 mRNA
CTD
PMID:20566472
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157
G
Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
methyl salicylate results in increased expression of AKR1B10 mRNA
CTD
PMID:20566472
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852
G
Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
methyl salicylate results in increased expression of AKR1C1 mRNA
CTD
PMID:20566472
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326
G
Akr1c3
aldo-keto reductase family 1, member C3
increases expression
ISO
methyl salicylate results in increased expression of AKR1C3 mRNA
CTD
PMID:20566472
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
methyl salicylate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]
CTD
PMID:36416909
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
G
Ccl3
C-C motif chemokine ligand 3
multiple interactions
ISO
methyl salicylate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein]
CTD
PMID:36416909
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
G
Ccnb1
cyclin B1
affects expression
ISO
methyl salicylate affects the expression of CCNB1 mRNA
CTD
PMID:22302311
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172
G
Cd5l
Cd5 molecule-like
affects expression
ISO
methyl salicylate affects the expression of CD5L mRNA
CTD
PMID:22302311
NCBI chr 2:175,088,915...175,099,928
Ensembl chr 2:172,790,934...172,829,753
G
Cdk1
cyclin-dependent kinase 1
affects expression
ISO
methyl salicylate affects the expression of CDK1 mRNA
CTD
PMID:22302311
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408
G
Creb1
cAMP responsive element binding protein 1
affects expression
ISO
methyl salicylate affects the expression of CREB1 mRNA
CTD
PMID:20385217
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816
G
Cxcl2
C-X-C motif chemokine ligand 2
decreases expression increases expression
ISO
methyl salicylate results in decreased expression of CXCL2 protein methyl salicylate results in increased expression of CXCL2 protein
CTD
PMID:23178550
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075
G
Emd
emerin
affects expression
ISO
methyl salicylate affects the expression of EMD mRNA
CTD
PMID:19527780
NCBI chr X:152,038,990...152,042,190
Ensembl chr X:152,038,998...152,045,807
G
Esr1
estrogen receptor 1
affects expression
ISO
methyl salicylate affects the expression of ESR1 mRNA
CTD
PMID:19527780
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
G
Esrrg
estrogen-related receptor gamma
multiple interactions
ISO
methyl salicylate inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]]
CTD
PMID:23583298
NCBI chr13:101,699,043...102,316,877
Ensembl chr13:99,564,669...99,783,397
G
Fech
ferrochelatase
increases expression
ISO
methyl salicylate results in increased expression of FECH mRNA
CTD
PMID:20566472
NCBI chr18:60,215,325...60,248,525
Ensembl chr18:57,945,122...57,979,348
G
Ftl1
ferritin light chain 1
increases expression
ISO
methyl salicylate results in increased expression of FTL mRNA
CTD
PMID:20566472
NCBI chr 1:105,072,858...105,074,705
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
G
G6pd
glucose-6-phosphate dehydrogenase
increases expression
ISO
methyl salicylate results in increased expression of G6PD mRNA
CTD
PMID:20566472
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
G
Gal3st1
galactose-3-O-sulfotransferase 1
affects expression
ISO
methyl salicylate affects the expression of GAL3ST1 mRNA
CTD
PMID:19527780
NCBI chr14:83,094,265...83,109,992
Ensembl chr14:78,870,793...78,886,388
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
methyl salicylate results in increased expression of GCLC mRNA
CTD
PMID:20566472
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
methyl salicylate results in increased expression of GCLM mRNA
CTD
PMID:20566472
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
G
Gsr
glutathione-disulfide reductase
increases expression
ISO
methyl salicylate results in increased expression of GSR mRNA
CTD
PMID:20566472
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
G
Hmox1
heme oxygenase 1
increases expression
ISO
methyl salicylate results in increased expression of HMOX1 mRNA
CTD
PMID:20566472
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
G
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases activity
ISO
methyl salicylate results in decreased activity of HSD3B1 protein
CTD
PMID:39159849
NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999
G
Il12b
interleukin 12B
multiple interactions
ISO
methyl salicylate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]
CTD
PMID:36416909
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
G
Il17a
interleukin 17A
decreases expression
ISO
methyl salicylate results in decreased expression of IL17A protein
CTD
PMID:28826779
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889
G
Il1a
interleukin 1 alpha
increases expression
ISO
methyl salicylate results in increased expression of IL1A protein
CTD
PMID:23178550
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
G
Il4
interleukin 4
affects expression
ISO
methyl salicylate affects the expression of IL4 mRNA
CTD
PMID:22302311
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
increases secretion
ISO
methyl salicylate results in increased secretion of IL6 protein
CTD
PMID:22245253
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
G
Itgav
integrin subunit alpha V
affects expression
ISO
methyl salicylate affects the expression of ITGAV mRNA
CTD
PMID:22302311
NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639
G
Lgals7
galectin 7
affects expression
ISO
methyl salicylate affects the expression of LGALS7 mRNA
CTD
PMID:22302311
NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
G
Mafg
MAF bZIP transcription factor G
increases expression
ISO
methyl salicylate results in increased expression of MAFG mRNA
CTD
PMID:20566472
NCBI chr10:106,401,633...106,410,159
Ensembl chr10:105,903,237...105,912,026
G
Me1
malic enzyme 1
increases expression
ISO
methyl salicylate results in increased expression of ME1 mRNA
CTD
PMID:20566472
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:87,549,043...87,660,304
G
Mki67
marker of proliferation Ki-67
affects expression
ISO
methyl salicylate affects the expression of MKI67 mRNA
CTD
PMID:22302311
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762
G
Ncoa2
nuclear receptor coactivator 2
multiple interactions
ISO
methyl salicylate inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]]
CTD
PMID:23583298
NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451
G
Nfkb1
nuclear factor kappa B subunit 1
decreases expression
ISO
methyl salicylate results in decreased expression of NFKB1 mRNA
CTD
PMID:20385217
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
G
Npr3
natriuretic peptide receptor 3
affects expression
ISO
methyl salicylate affects the expression of NPR3 mRNA
CTD
PMID:19527780
NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:60,870,594...60,932,955
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
methyl salicylate results in increased expression of NQO1 mRNA
CTD
PMID:20566472
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
G
Pgd
phosphogluconate dehydrogenase
increases expression
ISO
methyl salicylate results in increased expression of PGD mRNA
CTD
PMID:20566472
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:159,561,271...159,742,778
G
Ptgr1
prostaglandin reductase 1
increases expression
ISO
methyl salicylate results in increased expression of PTGR1 mRNA
CTD
PMID:20566472
NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:73,784,009...73,802,666
G
Srxn1
sulfiredoxin 1
increases expression
ISO
methyl salicylate results in increased expression of SRXN1 mRNA
CTD
PMID:20566472
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448
G
Thbs4
thrombospondin 4
affects expression
ISO
methyl salicylate affects the expression of THBS4 mRNA
CTD
PMID:22302311
NCBI chr 2:25,718,219...25,760,345
Ensembl chr 2:23,983,158...24,026,313
G
Timd2
T-cell immunoglobulin and mucin domain containing 2
affects expression
ISO
methyl salicylate affects the expression of TIMD2 mRNA
CTD
PMID:22302311
NCBI chr10:31,060,308...31,101,262
Ensembl chr10:31,060,326...31,094,623
G
Tnf
tumor necrosis factor
affects expression multiple interactions
ISO
methyl salicylate affects the expression of TNF mRNA methyl salicylate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]
CTD
PMID:20385217 PMID:36416909
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
G
Txnrd1
thioredoxin reductase 1
increases expression
ISO
methyl salicylate results in increased expression of TXNRD1 mRNA
CTD
PMID:20566472
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863
G
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
increases glucuronidation
ISO
UGT1A3 protein results in increased glucuronidation of methyl salicylate
CTD
PMID:15117964
NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a6
UDP glucuronosyltransferase family 1 member A6
increases metabolic processing affects metabolic processing
EXP
UGT1A6 protein results in increased metabolism of methyl salicylate UGT1A6 gene polymorphism affects the metabolism of methyl salicylate
CTD
PMID:9429234
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:88,713,184...88,808,465
G
Agt
angiotensinogen
multiple interactions
EXP
[nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein; nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein]; nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
CTD
PMID:33212213
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977
G
Agtr1a
angiotensin II receptor, type 1a
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]
CTD
PMID:33212213
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]
CTD
PMID:36169646
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
nerolidol results in increased expression of BAX mRNA
CTD
PMID:35357761
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
nerolidol results in decreased expression of BCL2 mRNA
CTD
PMID:35357761
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Casp3
caspase 3
increases expression
ISO
nerolidol results in increased expression of CASP3 mRNA
CTD
PMID:35357761
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
G
Cat
catalase
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein]
CTD
PMID:33212213 PMID:36169646
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
G
Ccnd1
cyclin D1
decreases expression
ISO
nerolidol results in decreased expression of CCND1 mRNA
CTD
PMID:35357761
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein]
CTD
PMID:36169646
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
G
Gck
glucokinase
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein]
CTD
PMID:36169646
NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]
CTD
PMID:36169646
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
G
Gpx4
glutathione peroxidase 4
multiple interactions
EXP
[nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein
CTD
PMID:33212213
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982
G
Il6
interleukin 6
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein]
CTD
PMID:33212213
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
G
Ins1
insulin 1
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]
CTD
PMID:36169646
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
G
Irs1
insulin receptor substrate 1
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein]
CTD
PMID:36169646
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]
CTD
PMID:33212213
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
CTD
PMID:33212213
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
nerolidol results in increased expression of and results in increased phosphorylation of MAPK8 mRNA
CTD
PMID:35357761
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
G
Mmp2
matrix metallopeptidase 2
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein]
CTD
PMID:33212213
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
G
Mmp9
matrix metallopeptidase 9
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein]
CTD
PMID:33212213
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
G
Nos2
nitric oxide synthase 2
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein]
CTD
PMID:33212213
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]
CTD
PMID:33212213
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein]
CTD
PMID:33212213
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
G
Slc2a4
solute carrier family 2 member 4
multiple interactions
EXP
nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]
CTD
PMID:36169646
NCBI chr10:55,164,721...55,170,289
Ensembl chr10:54,666,015...54,671,565
G
Sod2
superoxide dismutase 2
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein]
CTD
PMID:33212213
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]
CTD
PMID:33212213
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
G
Tlr4
toll-like receptor 4
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein]
CTD
PMID:33212213
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
G
Tnf
tumor necrosis factor
multiple interactions
EXP
nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein]
CTD
PMID:33212213
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
G
Tp53
tumor protein p53
affects binding
ISO
trimethyl phosphate binds to TP53 gene
CTD
PMID:25510514
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all