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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:indoleacetaldehyde
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Accession:CHEBI:24823 term browser browse the term
Definition:An aldehyde that is acetaldehyde substituted by an indolyl group.
Synonyms:related_synonym: indoleacetaldehydes


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(5-hydroxyindol-3-yl)acetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maoa monoamine oxidase A multiple interactions
increases abundance
EXP [MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde; Luteolin inhibits the reaction [[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde]; Luteolin inhibits the reaction [MAOA protein results in increased abundance of hydroxyindoleacetaldehyde]; Quercetin inhibits the reaction [[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde]; Quercetin inhibits the reaction [MAOA protein results in increased abundance of hydroxyindoleacetaldehyde] CTD PMID:23009399 NCBI chr  X:16,619,698...16,687,812
Ensembl chr  X:16,619,698...16,687,818
JBrowse link
indol-3-ylacetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO indoleacetaldehyde metabolite results in decreased activity of CYP1A1 protein CTD PMID:26686552 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Maoa monoamine oxidase A multiple interactions
increases chemical synthesis
ISO [[MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde
MAOA protein results in increased chemical synthesis of indoleacetaldehyde
CTD PMID:26686552 NCBI chr  X:16,619,698...16,687,812
Ensembl chr  X:16,619,698...16,687,818
JBrowse link
G Maob monoamine oxidase B multiple interactions
increases chemical synthesis
ISO [[MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde
MAOB protein results in increased chemical synthesis of indoleacetaldehyde
CTD PMID:26686552 NCBI chr  X:16,709,281...16,817,366
Ensembl chr  X:16,709,282...16,817,366
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21560
    role 21539
      chemical role 20811
        oxidising agent 10322
          acetaldehyde 544
            indoleacetaldehyde 3
              (5-hydroxyindol-3-yl)acetaldehyde 1
              indol-3-ylacetaldehyde 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 21560
    subatomic particle 21546
      composite particle 21546
        hadron 21546
          baryon 21546
            nucleon 21546
              atomic nucleus 21546
                atom 21546
                  main group element atom 21449
                    p-block element atom 21449
                      carbon group element atom 21240
                        carbon atom 21135
                          organic molecular entity 21135
                            organic group 19569
                              organic divalent group 19559
                                organodiyl group 19559
                                  carbonyl group 19540
                                    carbonyl compound 19540
                                      carboxylic acid 19125
                                        carboacyl group 17944
                                          univalent carboacyl group 17944
                                            formyl group 8884
                                              aldehyde 8884
                                                acetaldehyde 544
                                                  indoleacetaldehyde 3
                                                    (5-hydroxyindol-3-yl)acetaldehyde 1
                                                    indol-3-ylacetaldehyde 3
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