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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:indoleacetaldehyde
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Accession:CHEBI:24823 term browser browse the term
Definition:An aldehyde that is acetaldehyde substituted by an indolyl group.
Synonyms:related_synonym: indoleacetaldehydes


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(5-hydroxyindol-3-yl)acetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAOA monoamine oxidase A multiple interactions
increases abundance
ISO [MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde; Luteolin inhibits the reaction [[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde]; Luteolin inhibits the reaction [MAOA protein results in increased abundance of hydroxyindoleacetaldehyde]; Quercetin inhibits the reaction [[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde]; Quercetin inhibits the reaction [MAOA protein results in increased abundance of hydroxyindoleacetaldehyde] CTD PMID:23009399 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,824
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indol-3-ylacetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity EXP indoleacetaldehyde metabolite results in decreased activity of CYP1A1 protein CTD PMID:26686552 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G MAOA monoamine oxidase A multiple interactions
increases chemical synthesis
EXP [[MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde
MAOA protein results in increased chemical synthesis of indoleacetaldehyde
CTD PMID:26686552 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,824
JBrowse link
G MAOB monoamine oxidase B multiple interactions
increases chemical synthesis
EXP [[MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde
MAOB protein results in increased chemical synthesis of indoleacetaldehyde
CTD PMID:26686552 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24382
    role 24293
      chemical role 22503
        oxidising agent 10421
          acetaldehyde 554
            indoleacetaldehyde 3
              (5-hydroxyindol-3-yl)acetaldehyde 1
              indol-3-ylacetaldehyde 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 24382
    subatomic particle 24339
      composite particle 24339
        hadron 24339
          baryon 24339
            nucleon 24339
              atomic nucleus 24339
                atom 24339
                  main group element atom 24188
                    p-block element atom 24188
                      carbon group element atom 23967
                        carbon atom 23924
                          organic molecular entity 23924
                            organic group 22198
                              organic divalent group 22172
                                organodiyl group 22172
                                  carbonyl group 22155
                                    carbonyl compound 22155
                                      carboxylic acid 21201
                                        carboacyl group 19355
                                          univalent carboacyl group 19355
                                            formyl group 9739
                                              aldehyde 9739
                                                acetaldehyde 554
                                                  indoleacetaldehyde 3
                                                    (5-hydroxyindol-3-yl)acetaldehyde 1
                                                    indol-3-ylacetaldehyde 3
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