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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:indol-3-yl carboxylic acid
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Accession:CHEBI:24810 term browser browse the term
Definition:Any indolyl carboxylic acid carrying an indol-3-yl or substituted indol-3-yl group.
Synonyms:related_synonym: indol-3-yl carboxylic acids


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indometacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEXB hexosaminidase subunit beta multiple interactions EXP Indomethacin promotes the reaction [mastoparan results in increased secretion of HEXB protein] CTD PMID:21671308 NCBI chr 2:57,221,809...57,248,432
Ensembl chr 2:57,222,186...57,248,417 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Indomethacin results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 494
    role 501
      chemical role 420
        donor 395
          Bronsted acid 388
            oxoacid 373
              carbon oxoacid 364
                carboxylic acid 364
                  indolyl carboxylic acid 2
                    indol-3-yl carboxylic acid 2
                      3-(1H-indol-3-yl)propanoic acid 0
                      3-(5-benzyloxyindol-3-yl)pyruvic acid 0
                      3-(5-hydroxyindol-3-yl)pyruvic acid 0
                      3-(indol-3-yl)-2-oxobutyric acid + 0
                      3-(indol-3-yl)lactic acid 0
                      3-(indol-3-yl)pyruvic acid 0
                      acemetacin 0
                      indole-3-acetic acids + 2
                      indole-3-butyric acid + 0
                      indole-3-carboxylic acid + 0
                      indolmycenic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 494
    subatomic particle 494
      composite particle 494
        hadron 501
          baryon 494
            nucleon 494
              atomic nucleus 494
                atom 494
                  main group element atom 487
                    p-block element atom 487
                      carbon group element atom 476
                        carbon atom 482
                          organic molecular entity 475
                            organic molecule 466
                              organic cyclic compound 449
                                organic heterocyclic compound 419
                                  organic heteropolycyclic compound 96
                                    organic heterobicyclic compound 44
                                      benzopyrrole 8
                                        indoles 8
                                          indolyl carboxylic acid 2
                                            indol-3-yl carboxylic acid 2
                                              3-(1H-indol-3-yl)propanoic acid 0
                                              3-(5-benzyloxyindol-3-yl)pyruvic acid 0
                                              3-(5-hydroxyindol-3-yl)pyruvic acid 0
                                              3-(indol-3-yl)-2-oxobutyric acid + 0
                                              3-(indol-3-yl)lactic acid 0
                                              3-(indol-3-yl)pyruvic acid 0
                                              acemetacin 0
                                              indole-3-acetic acids + 2
                                              indole-3-butyric acid + 0
                                              indole-3-carboxylic acid + 0
                                              indolmycenic acid 0
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