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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxynitrile
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Accession:CHEBI:24730 term browser browse the term
Definition:Any nitrile compound which also contains a hydroxy group.


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(R)-amygdalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA] CTD PMID:33149750 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:33149750 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
3,5-dibromo-4-hydroxybenzonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 decreases activity EXP bromoxynil results in decreased activity of GJA1 protein CTD PMID:20510257 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Ttr transthyretin affects binding EXP bromoxynil binds to TTR protein CTD PMID:2043046 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      group 19741
        pseudohalo group 3490
          cyano group 3490
            nitrile 3490
              hydroxynitrile 4
                (4-hydroxyphenyl)acetonitrile 0
                2-hydroxyisobutyronitrile 0
                3,5-dibromo-4-hydroxybenzonitrile 2
                3-hydroxybutanenitrile + 0
                LLP-3 0
                alpha-hydroxynitrile + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            one-carbon compound 17665
                              hydrogen cyanide 3493
                                cyanides 3493
                                  nitrile 3490
                                    hydroxynitrile 4
                                      (4-hydroxyphenyl)acetonitrile 0
                                      2-hydroxyisobutyronitrile 0
                                      3,5-dibromo-4-hydroxybenzonitrile 2
                                      3-hydroxybutanenitrile + 0
                                      LLP-3 0
                                      alpha-hydroxynitrile + 2
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