Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxymethyl group
go back to main search page
Accession:CHEBI:24712 term browser browse the term
Synonyms:exact_synonym: hydroxymethyl
 related_synonym: -CH2-OH;   Formula=CH3O;   SMILES=C(*)O;   serine side-chain



show annotations for term's descendants           Sort by:
D-cycloserine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO Cycloserine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:34915026 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Cycloserine inhibits the reaction [resveratrol results in increased expression of DDIT3 protein] CTD PMID:24264887 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Egr1 early growth response 1 increases expression ISO Cycloserine results in increased expression of EGR1 protein CTD PMID:19144966 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO Cycloserine promotes the reaction [Clozapine results in increased expression of FOS mRNA] CTD PMID:12464447 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Homer1 homer scaffolding protein 1 multiple interactions ISO Cycloserine inhibits the reaction [Clozapine results in increased expression of HOMER1 mRNA]; Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein] CTD PMID:11903061 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein] CTD PMID:11903061 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO Cycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] CTD PMID:24264887 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
goralatide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme increases expression
decreases expression
multiple interactions
EXP goralatide results in increased expression of ACE mRNA
goralatide results in decreased expression of ACE mRNA
[BDKRB1 protein affects the activity of ACE protein] which affects the hydrolysis of goralatide; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of ACE mRNA]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of ACE protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in decreased expression of ACE2 mRNA]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in decreased expression of CDH1 protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of ACE mRNA]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of ACE protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of COL3A1 protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of VIM protein]]; goralatide affects the reaction [ACE2 protein affects the reaction [Silicon Dioxide results in increased expression of ACE mRNA]]; goralatide inhibits the reaction [AGT protein results in increased expression of ACE mRNA]; goralatide inhibits the reaction [AGT protein results in increased expression of ACE protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of ACE mRNA]
CTD PMID:20096676 PMID:33007385 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions EXP ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 mRNA]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of ACE mRNA]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of ACE protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGT protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in decreased expression of ACE2 mRNA]]; goralatide affects the reaction [ACE2 protein affects the reaction [AGT protein results in decreased abundance of angiotensin I (1-7)]]; goralatide affects the reaction [ACE2 protein affects the reaction [Silicon Dioxide results in decreased expression of ACE2 mRNA]]; goralatide affects the reaction [ACE2 protein affects the reaction [Silicon Dioxide results in decreased expression of ACE2 protein]]; goralatide affects the reaction [ACE2 protein affects the reaction [Silicon Dioxide results in increased expression of ACE mRNA]]; goralatide affects the reaction [ACE2 protein affects the reaction [Silicon Dioxide results in increased expression of AGT protein]]; goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 mRNA]; goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of ACE2 mRNA]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of ACE2 protein] CTD PMID:33007385 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO
EXP
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]
goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]]; goralatide inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]
CTD PMID:31181250 PMID:33007385 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Agt angiotensinogen multiple interactions EXP
ISO
ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 mRNA]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of ACE mRNA]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of ACE protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGT protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]]; ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]]; goralatide affects the reaction [ACE2 protein affects the reaction [AGT protein results in decreased abundance of angiotensin I (1-7)]]; goralatide affects the reaction [ACE2 protein affects the reaction [Silicon Dioxide results in increased expression of AGT protein]]; goralatide inhibits the reaction [AGT protein results in decreased abundance of angiotensin I (1-7)]; goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 mRNA]; goralatide inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]; goralatide inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]; goralatide inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of ACE mRNA]; goralatide inhibits the reaction [AGT protein results in increased expression of ACE protein]; goralatide inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of AGT protein]; goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; goralatide inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of VIM protein]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of AGT protein alternative form]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of AGT protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of GLI3 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of PTCH1 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI1 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI2 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SHH protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SMO protein]; goralatide inhibits the reaction [AGT protein results in decreased expression of GLI3 protein]; goralatide inhibits the reaction [AGT protein results in decreased expression of PTCH1 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of GLI1 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of GLI2 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of SHH protein]; goralatide inhibits the reaction [AGT protein results in increased expression of SMO protein]
CTD PMID:31181250 PMID:33007385 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]]; goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of AGTR1 protein] CTD PMID:33007385 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 affects abundance
multiple interactions
EXP BDKRB1 protein affects the abundance of goralatide
[BDKRB1 protein affects the activity of ACE protein] which affects the hydrolysis of goralatide
CTD PMID:20096676 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in decreased expression of CDH1 protein]]; goralatide inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:33007385 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Col3a1 collagen, type III, alpha 1 multiple interactions EXP ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]]; goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of COL3A1 protein]]; goralatide inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of COL3A1 protein] CTD PMID:33007385 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Gli1 GLI-Kruppel family member GLI1 multiple interactions ISO [goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI1 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of GLI1 protein]
CTD PMID:31181250 NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843
JBrowse link
G Gli2 GLI-Kruppel family member GLI2 multiple interactions ISO [goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI2 protein]; goralatide inhibits the reaction [AGT protein results in increased expression of GLI2 protein]
CTD PMID:31181250 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349
JBrowse link
G Gli3 GLI-Kruppel family member GLI3 multiple interactions ISO [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of GLI3 protein]; goralatide inhibits the reaction [AGT protein results in decreased expression of GLI3 protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in decreased expression of GLI3 protein]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of GLI3 protein]
CTD PMID:31181250 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611
JBrowse link
G Mas1 MAS1 oncogene multiple interactions EXP ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]]; goralatide inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of MAS1 protein] CTD PMID:33007385 NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030
JBrowse link
G Ptch1 patched 1 multiple interactions ISO [goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in decreased expression of PTCH1 protein]; goralatide inhibits the reaction [Silicon Dioxide results in decreased expression of PTCH1 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of PTCH1 protein]; goralatide inhibits the reaction [AGT protein results in decreased expression of PTCH1 protein]
CTD PMID:31181250 NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412
JBrowse link
G Shh sonic hedgehog multiple interactions ISO [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SHH protein]; goralatide inhibits the reaction [AGT protein results in increased expression of SHH protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of SHH protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of SHH protein]
CTD PMID:31181250 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
JBrowse link
G Smo smoothened, frizzled class receptor multiple interactions ISO [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SMO protein]; goralatide inhibits the reaction [AGT protein results in increased expression of SMO protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of SMO protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of SMO protein]
CTD PMID:31181250 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364
JBrowse link
G Vim vimentin multiple interactions EXP goralatide affects the reaction [ACE protein affects the reaction [Silicon Dioxide results in increased expression of VIM protein]]; goralatide inhibits the reaction [AGT protein results in increased expression of VIM protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of VIM protein] CTD PMID:33007385 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
L-serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine affects the localization of TARDBP protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in decreased expression of SLC1A2 protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of APP protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of IL6 protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of MAP1LC3B protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:30476904 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of APP protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of APP protein] CTD PMID:30476904 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Serine results in increased expression of ATF4 mRNA CTD PMID:29098664 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Serine results in increased expression of ATF6 mRNA CTD PMID:29098664 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Serine results in increased expression of ATF6B mRNA CTD PMID:29098664 NCBI chr17:34,866,120...34,874,048
Ensembl chr17:34,866,120...34,874,048
JBrowse link
G Atxn3 ataxin 3 increases expression ISO Serine results in increased expression of ATXN3 mRNA CTD PMID:29098664 NCBI chr12:101,885,160...101,928,139
Ensembl chr12:101,885,160...101,924,505
JBrowse link
G Bax BCL2-associated X protein increases expression ISO Serine results in increased expression of BAX mRNA CTD PMID:29098664 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Calr calreticulin increases expression ISO Serine results in increased expression of CALR mRNA CTD PMID:29098664 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
JBrowse link
G Canx calnexin increases expression ISO Serine results in increased expression of CANX mRNA CTD PMID:29098664 NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression ISO Serine results in increased expression of CCT4 mRNA CTD PMID:29098664 NCBI chr11:22,940,593...22,953,336
Ensembl chr11:22,940,519...22,953,780
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression ISO Serine results in increased expression of CCT7 mRNA CTD PMID:29098664 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Serine results in decreased expression of CEBPB mRNA CTD PMID:29098664 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Derl2 Der1-like domain family, member 2 increases expression ISO Serine results in increased expression of DERL2 mRNA CTD PMID:29098664 NCBI chr11:70,898,266...70,910,667
Ensembl chr11:70,897,990...70,910,667
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 increases expression ISO Serine results in increased expression of DNAJB2 mRNA CTD PMID:29098664 NCBI chr 1:75,213,039...75,222,336
Ensembl chr 1:75,213,050...75,222,336
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Serine results in increased expression of DNAJB9 mRNA CTD PMID:29098664 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Serine results in increased expression of DNAJC3 mRNA CTD PMID:29098664 NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 increases expression ISO Serine results in increased expression of DNAJC4 mRNA CTD PMID:29098664 NCBI chr19:6,965,279...6,969,954
Ensembl chr19:6,965,279...6,969,940
JBrowse link
G Edem1 ER degradation enhancer, mannosidase alpha-like 1 increases expression ISO Serine results in increased expression of EDEM1 mRNA CTD PMID:29098664 NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases expression ISO Serine results in increased expression of EIF2A mRNA CTD PMID:29098664 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922
JBrowse link
G Erp44 endoplasmic reticulum protein 44 increases expression ISO Serine results in increased expression of ERP44 mRNA CTD PMID:29098664 NCBI chr 4:48,190,711...48,279,635
Ensembl chr 4:48,193,323...48,279,558
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein] CTD PMID:30476904 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 increases expression ISO Serine results in increased expression of HERPUD1 mRNA CTD PMID:29098664 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hsf1 heat shock factor 1 increases activity ISO Serine results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
JBrowse link
G Hspa1b heat shock protein 1B decreases expression ISO Serine results in decreased expression of HSPA1B mRNA CTD PMID:29098664 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Hspa1l heat shock protein 1-like increases expression ISO Serine results in increased expression of HSPA1L mRNA CTD PMID:29098664 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
JBrowse link
G Htra4 HtrA serine peptidase 4 decreases expression ISO Serine results in decreased expression of HTRA4 mRNA CTD PMID:29098664 NCBI chr 8:25,514,944...25,529,160
Ensembl chr 8:25,514,945...25,528,978
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of IL6 protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of IL6 protein] CTD PMID:30476904 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Lamc1 laminin, gamma 1 multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine affects the localization of TARDBP protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in decreased expression of SLC1A2 protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of APP protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of IL6 protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of MAP1LC3B protein]; [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:30476904 NCBI chr 1:153,094,668...153,208,532
Ensembl chr 1:153,094,668...153,208,532
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of MAP1LC3B protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of MAP1LC3B protein] CTD PMID:30476904 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mapk10 mitogen-activated protein kinase 10 decreases expression ISO Serine results in decreased expression of MAPK10 mRNA CTD PMID:29098664 NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:30476904 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide increases expression ISO Serine results in increased expression of P4HB protein CTD PMID:28975502 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO Serine results in decreased expression of PPP1R15A mRNA CTD PMID:29098664 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in decreased expression of SLC1A2 protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine results in decreased expression of SLC1A2 protein] CTD PMID:30476904 NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Serine results in decreased expression of SREBF1 mRNA CTD PMID:29098664 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srr serine racemase multiple interactions ISO SRR protein results in increased abundance of and results in increased secretion of Serine analog CTD PMID:27387750 NCBI chr11:74,794,853...74,818,427
Ensembl chr11:74,797,185...74,816,774
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine affects the localization of TARDBP protein]; Serine inhibits the reaction [beta-N-methylamino-L-alanine affects the localization of TARDBP protein] CTD PMID:30476904 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 decreases expression ISO Serine results in decreased expression of UBE2G2 mRNA CTD PMID:29098664 NCBI chr10:77,458,155...77,481,824
Ensembl chr10:77,458,109...77,481,827
JBrowse link
G Vcp valosin containing protein decreases expression ISO Serine results in decreased expression of VCP mRNA CTD PMID:29098664 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
JBrowse link
Phe-Ser term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 affects binding ISO phenylalanylserine analog binds to SLC15A1 protein CTD PMID:21147219 NCBI chr14:121,697,033...121,742,666
Ensembl chr14:121,697,033...121,742,664
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22188
    role 22173
      application 21755
        fuel 11473
          methanol 3990
            hydroxymethyl group 64
              N-(2,4-dinitrophenyl)-L-serine 0
              N-(2,4-dinitrophenyl)serine 0
              serine + 64
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    p-block element atom 22114
                      chalcogen 21436
                        oxygen atom 21414
                          oxygen molecular entity 21414
                            hydroxides 20789
                              organic hydroxy compound 19718
                                alcohol 15856
                                  aliphatic alcohol 12061
                                    alkyl alcohol 11967
                                      methanol 3990
                                        hydroxymethyl group 64
                                          N-(2,4-dinitrophenyl)-L-serine 0
                                          N-(2,4-dinitrophenyl)serine 0
                                          serine + 64
paths to the root