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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:secondary alpha-hydroxy ketone
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Accession:CHEBI:2468 term browser browse the term
Definition:An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing one hydrogen and one organyl group. Secondary alpha-hydroxy ketones are also known as acyloins, and are formally derived from reductive coupling of two carboxylic acid groups.
Synonyms:related_synonym: Formula=C2H2O2R2;   SMILES=C(C(=O)*)(O)([H])*;   acyloin;   acyloins;   secondary alpha-hydroxy-ketones;   secondary alpha-hydroxyketone;   secondary alpha-hydroxyketones
 xref: Wikipedia:Acyloin


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(+)-dihydromyricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein] CTD PMID:21871475 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:21871475 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Sphk1 sphingosine kinase 1 decreases expression
decreases activity
ISO ampelopsin results in decreased expression of SPHK1 protein
ampelopsin results in decreased activity of SPHK1 protein
CTD PMID:22251058 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
(+)-taxifolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO taxifolin inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione]
taxifolin results in decreased activity of ABCC1 protein
CTD PMID:15041478 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Afp alpha-fetoprotein affects binding EXP taxifolin binds to AFP protein CTD PMID:23013281, PMID:25349334 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agt angiotensinogen decreases expression ISO taxifolin results in decreased expression of AGT protein modified form CTD PMID:24269735 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR gene mutant form inhibits the reaction [taxifolin results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [taxifolin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO taxifolin results in increased expression of APOA1 protein CTD PMID:11108730 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B decreases secretion
decreases expression
ISO taxifolin results in decreased secretion of APOB protein
taxifolin results in decreased expression of APOB protein
CTD PMID:11108730, PMID:15380446 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of BCL2 protein] CTD PMID:32525071 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 decreases activity EXP taxifolin results in decreased activity of CASP3 protein CTD PMID:24269735 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 decreases activity EXP taxifolin results in decreased activity of CASP9 protein CTD PMID:24269735 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP taxifolin analog inhibits the reaction [Dietary Fats results in decreased activity of CAT protein]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of CAT mRNA] CTD PMID:30372826, PMID:32525071 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO taxifolin results in decreased expression of CCNA1 mRNA CTD PMID:17541156 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO taxifolin results in decreased expression of CDC25A mRNA CTD PMID:17541156 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP taxifolin analog inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] CTD PMID:30372826 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cycs cytochrome c, somatic affects localization EXP taxifolin affects the localization of CYCS protein CTD PMID:24269735 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of CYP11A1 mRNA]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of CYP11A1 protein] CTD PMID:32525071 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO taxifolin results in increased expression of CYP1A1 mRNA; taxifolin results in increased expression of CYP1A1 protein
AHR gene mutant form inhibits the reaction [taxifolin results in increased expression of CYP1A1 mRNA]
CTD PMID:22422552, PMID:29584932 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO taxifolin results in decreased expression of CYP2E1 mRNA CTD PMID:17541156 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dcc DCC netrin 1 receptor increases expression ISO taxifolin results in increased expression of DCC mRNA CTD PMID:17541156 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Egf epidermal growth factor decreases expression ISO taxifolin results in decreased expression of EGF mRNA CTD PMID:17541156 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Fgf18 fibroblast growth factor 18 decreases expression ISO taxifolin results in decreased expression of FGF18 mRNA CTD PMID:17541156 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391
JBrowse link
G Fgf3 fibroblast growth factor 3 decreases expression ISO taxifolin results in decreased expression of FGF3 mRNA CTD PMID:17541156 NCBI chr 1:218,003,018...218,006,942
Ensembl chr 1:218,003,018...218,006,942
JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO taxifolin results in increased expression of GAS6 mRNA CTD PMID:17541156 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO taxifolin results in increased expression of GDF15 mRNA CTD PMID:17541156 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of GPX1 mRNA]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of GPX1 protein] CTD PMID:32525071 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO taxifolin results in increased expression of GSTM1 mRNA CTD PMID:17541156 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
ISO taxifolin results in increased expression of HMOX1 protein
Chlorpyrifos inhibits the reaction [taxifolin results in decreased expression of HMOX1 protein]
CTD PMID:16799064, PMID:31152760 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of HSD17B3 mRNA]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of HSD17B3 protein] CTD PMID:32525071 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 mRNA]; taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein] CTD PMID:12044887, PMID:19103272 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma multiple interactions ISO taxifolin inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of STAT1 protein]; taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 mRNA]; taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein]
taxifolin inhibits the reaction [Chlorpyrifos results in increased secretion of IFNG protein]
CTD PMID:12044887, PMID:19103272, PMID:31152760 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Insl3 insulin-like 3 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of INSL3 mRNA]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of INSL3 protein] CTD PMID:32525071 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO taxifolin results in decreased expression of JUN mRNA CTD PMID:17541156 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein] CTD PMID:12044887 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases activity ISO taxifolin results in decreased activity of MTTP protein CTD PMID:15380446 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
decreases expression
multiple interactions
ISO taxifolin results in increased expression of NFE2L2 protein
taxifolin results in decreased expression of NFE2L2 protein
Chlorpyrifos inhibits the reaction [taxifolin results in decreased expression of NFE2L2 protein]
CTD PMID:16799064, PMID:31152760 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
ISO taxifolin results in increased activity of NQO1 protein
taxifolin results in increased expression of NQO1 mRNA
CTD PMID:17541156 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pdgfb platelet derived growth factor subunit B decreases expression ISO taxifolin results in decreased expression of PDGFB mRNA CTD PMID:17541156 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of PPARGC1A protein] CTD PMID:32525071 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO taxifolin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rasa1 RAS p21 protein activator 1 decreases expression ISO taxifolin results in decreased expression of RASA1 mRNA CTD PMID:17541156 NCBI chr 2:13,617,021...13,696,531
Ensembl chr 2:13,616,822...13,696,426
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of SIRT1 protein] CTD PMID:32525071 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of SOD1 mRNA]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of SOD1 protein] CTD PMID:32525071 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of SOD2 mRNA] CTD PMID:32525071 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions EXP taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of SOX9 mRNA] CTD PMID:32525071 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO taxifolin inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of STAT1 protein] CTD PMID:12044887 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO taxifolin inhibits the reaction [Chlorpyrifos results in increased secretion of TNF protein] CTD PMID:31152760 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Traf3 Tnf receptor-associated factor 3 increases expression ISO taxifolin results in increased expression of TRAF3 mRNA CTD PMID:17541156 NCBI chr 6:135,610,698...135,720,247
Ensembl chr 6:135,610,743...135,718,564
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
decreases activity
ISO
EXP
taxifolin results in increased expression of TXNRD1 mRNA
taxifolin results in decreased activity of TXNRD1 protein modified form
CTD PMID:16618767, PMID:17541156 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP taxifolin analog inhibits the reaction [Dietary Fats results in decreased expression of UCP1 mRNA] CTD PMID:30372826 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions
ISO taxifolin results in increased expression of UGT1A1 mRNA
AHR gene mutant form inhibits the reaction [taxifolin results in increased expression of UGT1A1 mRNA]
CTD PMID:29584932 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO taxifolin inhibits the reaction [XDH protein results in increased chemical synthesis of Superoxides] CTD PMID:19555678 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor increases expression ISO taxifolin results in increased expression of XPA mRNA CTD PMID:17541156 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 increases expression ISO taxifolin results in increased expression of XRCC4 mRNA CTD PMID:17541156 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
(R)-acetoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases reduction
multiple interactions
ISO AKR1B1 protein results in increased reduction of Acetoin
[AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B1 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
ISO AKR1B10 protein results in increased reduction of Acetoin
[AKR1B10 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B10 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 1,4-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 9,10-phenanthrenequinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; [[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin; [DCXR protein co-treated with NAD] results in increased chemical synthesis of Acetoin; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin] CTD PMID:28595002 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
15-acetyldeoxynivalenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ADRB2 mRNA CTD PMID:23792671 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ANGPTL4 mRNA CTD PMID:23792671 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ar androgen receptor decreases activity
multiple interactions
ISO 15-acetyldeoxynivalenol results in decreased activity of AR protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein
CTD PMID:27481073 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ARC mRNA CTD PMID:23792671 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Areg amphiregulin increases expression ISO 15-acetyldeoxynivalenol results in increased expression of AREG mRNA CTD PMID:23792671 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ARID5A mRNA CTD PMID:23792671 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ARL5B mRNA CTD PMID:23792671 NCBI chr17:82,065,893...82,092,693
Ensembl chr17:82,065,937...82,091,362
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ARRDC4 mRNA CTD PMID:23792671 NCBI chr 1:129,766,097...129,780,076
Ensembl chr 1:129,766,100...129,780,356
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO 15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA
[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA]
CTD PMID:19101521, PMID:22003189, PMID:23792671 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ATF6 mRNA CTD PMID:20682335 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of BDKRB1 mRNA CTD PMID:23792671 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of BDKRB2 mRNA CTD PMID:23792671 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of BHLHE40 mRNA CTD PMID:23792671 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of BTG2 mRNA CTD PMID:23792671 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Ccdc116 coiled-coil domain containing 116 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCDC116 mRNA CTD PMID:23792671 NCBI chr11:88,092,794...88,100,220
Ensembl chr11:88,095,170...88,098,252
JBrowse link
G Cck cholecystokinin increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCK protein CTD PMID:24385417 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCL2 mRNA CTD PMID:24793808 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCL3 mRNA CTD PMID:23792671 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCL4 mRNA CTD PMID:23792671 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCL7 mRNA CTD PMID:24793808 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CCR7 mRNA CTD PMID:23792671 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CREM mRNA CTD PMID:23792671 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CXCL2 mRNA CTD PMID:24793808 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of CXCR4 mRNA CTD PMID:23792671 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DDIT3 mRNA CTD PMID:23792671 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DIXDC1 mRNA CTD PMID:23792671 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dlx1 distal-less homeobox 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DLX1 mRNA CTD PMID:23792671 NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DLX2 mRNA CTD PMID:23792671 NCBI chr 3:58,180,088...58,181,971
Ensembl chr 3:58,180,088...58,181,971
JBrowse link
G Dmrt2 doublesex and mab-3 related transcription factor 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DMRT2 mRNA CTD PMID:23792671 NCBI chr 1:243,662,819...243,669,312
Ensembl chr 1:243,662,823...243,669,312
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DNAJB5 mRNA CTD PMID:23792671 NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DUSP10 mRNA CTD PMID:23792671 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of DUSP8 mRNA CTD PMID:23792671 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Egr3 early growth response 3 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of EGR3 mRNA CTD PMID:23792671 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO 15-acetyldeoxynivalenol results in increased phosphorylation of EIF2A protein CTD PMID:20682335 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Emx2 empty spiracles homeobox 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of EMX2 mRNA CTD PMID:23792671 NCBI chr 1:280,633,938...280,640,946
Ensembl chr 1:280,633,938...280,640,946
JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of EPHB3 mRNA CTD PMID:23792671 NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
JBrowse link
G Ereg epiregulin increases expression ISO 15-acetyldeoxynivalenol results in increased expression of EREG mRNA CTD PMID:23792671 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO 15-acetyldeoxynivalenol results in decreased expression of ERN1 mRNA CTD PMID:20682335 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Fam214b family with sequence similarity 214, member B increases expression ISO 15-acetyldeoxynivalenol results in increased expression of FAM214B mRNA CTD PMID:23792671 NCBI chr 5:58,477,894...58,484,900
Ensembl chr 5:58,477,894...58,484,900
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO 15-acetyldeoxynivalenol results in increased expression of FAM43A mRNA CTD PMID:23792671 NCBI chr11:73,676,601...73,679,003
Ensembl chr11:73,676,601...73,678,984
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of FBP2 mRNA CTD PMID:23792671 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of FGF9 mRNA CTD PMID:23792671 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fjx1 four-jointed box kinase 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of FJX1 mRNA CTD PMID:23792671 NCBI chr 3:92,288,818...92,290,919
Ensembl chr 3:92,288,818...92,290,919
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO 15-acetyldeoxynivalenol results in increased expression of GEM mRNA CTD PMID:23792671 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of GFOD1 mRNA CTD PMID:23792671 NCBI chr17:23,818,370...23,924,393
Ensembl chr17:23,823,632...23,923,792
JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of GTF2IRD2 mRNA CTD PMID:23792671 NCBI chr12:25,509,059...25,555,554
Ensembl chr12:25,509,653...25,546,200
JBrowse link
G Has2 hyaluronan synthase 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of HAS2 mRNA CTD PMID:23792671 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hoxb2 homeobox B2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of HOXB2 mRNA CTD PMID:23792671 NCBI chr10:84,200,859...84,203,065
Ensembl chr10:84,200,880...84,202,688
JBrowse link
G Hpse2 heparanase 2 (inactive) increases expression ISO 15-acetyldeoxynivalenol results in increased expression of HPSE2 mRNA CTD PMID:23792671 NCBI chr 1:262,020,903...263,138,299 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO 15-acetyldeoxynivalenol results in decreased expression of HSPA5 mRNA CTD PMID:20682335 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO 15-acetyldeoxynivalenol results in increased expression of IL10RA mRNA CTD PMID:23792671 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il1b interleukin 1 beta increases expression ISO 15-acetyldeoxynivalenol results in increased expression of IL1B mRNA CTD PMID:23792671, PMID:24793808 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 affects secretion
increases expression
ISO 15-acetyldeoxynivalenol affects the secretion of IL2 protein
15-acetyldeoxynivalenol results in increased expression of IL2 mRNA
CTD PMID:8560498 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 affects secretion ISO 15-acetyldeoxynivalenol affects the secretion of IL4 protein CTD PMID:8560498 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 affects secretion ISO 15-acetyldeoxynivalenol affects the secretion of IL5 protein CTD PMID:8560498 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of IL6 mRNA CTD PMID:8560498, PMID:24793808 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Iqcn IQ motif containing N increases expression ISO 15-acetyldeoxynivalenol results in increased expression of IQCN mRNA CTD PMID:23792671 NCBI chr16:20,467,425...20,483,375 JBrowse link
G Irgm immunity-related GTPase M increases expression ISO 15-acetyldeoxynivalenol results in increased expression of IRGM mRNA CTD PMID:23792671 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of KCNJ2 mRNA CTD PMID:23792671 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Klf10 Kruppel-like factor 10 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of KLF10 mRNA CTD PMID:23792671 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of MAN1B1 mRNA CTD PMID:23792671 NCBI chr 3:2,547,259...2,569,051
Ensembl chr 3:2,547,986...2,569,049
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A increases expression ISO 15-acetyldeoxynivalenol results in increased expression of MFSD2A mRNA CTD PMID:23792671 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mras muscle RAS oncogene homolog increases expression ISO 15-acetyldeoxynivalenol results in increased expression of MRAS mRNA CTD PMID:23792671 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of MXD1 mRNA CTD PMID:23792671 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of NEURL3 mRNA CTD PMID:23792671 NCBI chr 9:42,831,737...42,841,765
Ensembl chr 9:42,831,742...42,839,837
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions ISO [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA] CTD PMID:22003189 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of NR4A3 mRNA CTD PMID:23792671 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of NWD2 mRNA CTD PMID:23792671 NCBI chr14:46,136,780...46,153,320
Ensembl chr14:46,136,786...46,153,212
JBrowse link
G Pcdh9 protocadherin 9 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of PCDH9 mRNA CTD PMID:23792671 NCBI chr15:76,787,108...77,738,668
Ensembl chr15:77,733,402...77,736,892
JBrowse link
G Per1 period circadian regulator 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of PER1 mRNA CTD PMID:23792671 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity ISO 15-acetyldeoxynivalenol results in decreased activity of PPARG protein CTD PMID:27481073 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of PTGS2 mRNA CTD PMID:14514436 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of RCAN1 mRNA CTD PMID:23792671 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rem2 RRAD and GEM like GTPase 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of REM2 mRNA CTD PMID:23792671 NCBI chr15:33,121,273...33,125,752
Ensembl chr15:33,121,273...33,125,752
JBrowse link
G RGD1564664 similar to LOC387763 protein increases expression ISO 15-acetyldeoxynivalenol results in increased expression of C11ORF96 mRNA CTD PMID:23792671 NCBI chr 3:82,854,779...82,856,171
Ensembl chr 3:82,854,777...82,856,171
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of RGS16 mRNA CTD PMID:23792671 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rhoh ras homolog family member H increases expression ISO 15-acetyldeoxynivalenol results in increased expression of RHOH mRNA CTD PMID:23792671 NCBI chr14:43,961,756...43,992,587
Ensembl chr14:43,961,756...43,992,587
JBrowse link
G Rnd1 Rho family GTPase 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of RND1 mRNA CTD PMID:23792671 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Six1 SIX homeobox 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of SIX1 mRNA CTD PMID:23792671 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Slc34a1 solute carrier family 34 member 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of SLC34A1 mRNA CTD PMID:23792671 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813
JBrowse link
G Stmn4 stathmin 4 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of STMN4 mRNA CTD PMID:23792671 NCBI chr15:43,007,901...43,025,852
Ensembl chr15:43,007,908...43,025,852
JBrowse link
G Stox2 storkhead box 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of STOX2 mRNA CTD PMID:23792671 NCBI chr16:47,994,555...48,233,588
Ensembl chr16:48,120,864...48,228,891
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO 15-acetyldeoxynivalenol results in increased expression of TFAP2A mRNA CTD PMID:23792671 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein CTD PMID:27481073 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of TMCC2 mRNA CTD PMID:23792671 NCBI chr13:49,132,685...49,169,771
Ensembl chr13:49,132,667...49,169,918
JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of TMEM88 mRNA CTD PMID:23792671 NCBI chr10:55,998,530...56,000,225
Ensembl chr10:55,998,530...56,000,225
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 15-acetyldeoxynivalenol results in increased expression of TNF mRNA CTD PMID:23792671, PMID:24793808 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of UCP1 mRNA CTD PMID:23792671 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Zbtb21 zinc finger and BTB domain containing 21 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ZBTB21 mRNA CTD PMID:23792671 NCBI chr11:38,442,716...38,457,411
Ensembl chr11:38,442,742...38,457,373
JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ZC3H12D mRNA CTD PMID:23792671 NCBI chr 1:1,937,620...1,972,919
Ensembl chr 1:1,938,419...1,972,918
JBrowse link
G Zfp2 zinc finger protein 2 increases expression ISO 15-acetyldeoxynivalenol results in increased expression of ZFP2 mRNA CTD PMID:23792671 NCBI chr10:36,388,136...36,406,721
Ensembl chr10:36,388,137...36,402,619
JBrowse link
3-acetyldeoxynivalenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor decreases activity
multiple interactions
ISO 3-acetyldeoxynivalenol results in decreased activity of AR protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein
CTD PMID:27481073 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of ATF6 mRNA CTD PMID:20682335 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Cck cholecystokinin increases expression ISO 3-acetyldeoxynivalenol results in increased expression of CCK protein CTD PMID:24385417 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of CCL2 mRNA CTD PMID:24793808 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of CCL7 mRNA CTD PMID:24793808 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of CXCL2 mRNA CTD PMID:24793808 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO 3-acetyldeoxynivalenol results in increased phosphorylation of EIF2A protein CTD PMID:20682335 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA CTD PMID:20682335 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO 3-acetyldeoxynivalenol results in decreased expression of HSPA5 mRNA CTD PMID:20682335 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il1b interleukin 1 beta increases expression ISO 3-acetyldeoxynivalenol results in increased expression of IL1B mRNA CTD PMID:24793808 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 affects secretion
increases expression
ISO 3-acetyldeoxynivalenol affects the secretion of IL2 protein
3-acetyldeoxynivalenol results in increased expression of IL2 mRNA
CTD PMID:8560498 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 affects secretion ISO 3-acetyldeoxynivalenol affects the secretion of IL4 protein CTD PMID:8560498 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 affects secretion ISO 3-acetyldeoxynivalenol affects the secretion of IL5 protein CTD PMID:8560498 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of IL6 mRNA CTD PMID:24793808 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity ISO 3-acetyldeoxynivalenol results in decreased activity of PPARG protein CTD PMID:27481073 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO 3-acetyldeoxynivalenol results in increased expression of PTGS2 mRNA CTD PMID:14514436 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Thrb thyroid hormone receptor beta decreases activity
multiple interactions
ISO 3-acetyldeoxynivalenol results in decreased activity of THRB protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein
CTD PMID:27481073 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 3-acetyldeoxynivalenol results in increased expression of TNF mRNA CTD PMID:24793808 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
acetoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases reduction
multiple interactions
ISO AKR1B1 protein results in increased reduction of Acetoin
[AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B1 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
ISO AKR1B10 protein results in increased reduction of Acetoin
[AKR1B10 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B10 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 1,4-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 9,10-phenanthrenequinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; [[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin; [DCXR protein co-treated with NAD] results in increased chemical synthesis of Acetoin; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin] CTD PMID:28595002 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
astilbin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in decreased phosphorylation of AKT1 protein] CTD PMID:29471006 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:29471006 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:29471006 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] CTD PMID:29471006 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein] CTD PMID:29471006 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in decreased activity of CAT protein] CTD PMID:29471006 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in decreased expression of GCLC mRNA] CTD PMID:29471006 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] CTD PMID:29471006 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased expression of IL1B protein] CTD PMID:29471006 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased expression of IL6 protein] CTD PMID:29471006 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK1 protein] CTD PMID:29471006 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK3 protein] CTD PMID:29471006 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO astilbin promotes the reaction [Cisplatin affects the localization of NFE2L2 protein]
astilbin promotes the reaction [Cisplatin results in increased expression of NFE2L2 protein]
CTD PMID:29471006 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased phosphorylation of NFKBIA protein] CTD PMID:29471006 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased expression of NOS2 protein] CTD PMID:29471006 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO astilbin promotes the reaction [Cisplatin results in increased expression of NQO1 mRNA] CTD PMID:29471006 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:29471006 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased expression of PTGS2 protein] CTD PMID:29471006 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein] CTD PMID:29471006 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO astilbin promotes the reaction [Cisplatin results in increased expression of TNF mRNA]
astilbin inhibits the reaction [Cisplatin results in increased expression of TNF protein]
CTD PMID:29471006 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO astilbin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] CTD PMID:29471006 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
cabazitaxel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1s1 AKT1 substrate 1 decreases expression ISO cabazitaxel results in decreased expression of AKT1S1 protein CTD PMID:32525019 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Foxo3 forkhead box O3 affects expression ISO cabazitaxel affects the expression of FOXO3 protein CTD PMID:32525019 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
chaetoglobosin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
EXP chaetoglobosins results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of AKT1 protein]
CTD PMID:18040759 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP chaetoglobosins inhibits the reaction [Dieldrin results in decreased phosphorylation of GJA1 protein]; chaetoglobosins inhibits the reaction [Hexachlorocyclohexane results in decreased phosphorylation of GJA1 protein] CTD PMID:18040759 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
EXP chaetoglobosins results in increased phosphorylation of GSK3B protein
wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]
CTD PMID:18040759 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP chaetoglobosins results in increased phosphorylation of MAPK1 protein CTD PMID:18040759 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP chaetoglobosins results in increased phosphorylation of MAPK3 protein CTD PMID:18040759 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases phosphorylation EXP chaetoglobosins results in decreased phosphorylation of RAF1 protein CTD PMID:18040759 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO chaetoglobosins results in increased expression of and results in increased secretion of TNF protein CTD PMID:28535995 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
cucurbitacin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA] CTD PMID:29250925 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO cucurbitacin B results in decreased expression of ADIPOQ mRNA CTD PMID:24316209 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAX mRNA] CTD PMID:29250925 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2 mRNA] CTD PMID:29250925 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cat catalase multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:29250925 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO cucurbitacin B results in decreased expression of CCND1 CTD PMID:24316209 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd36 CD36 molecule decreases expression ISO cucurbitacin B results in decreased expression of CD36 mRNA CTD PMID:24316209 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions
ISO cucurbitacin B results in decreased expression of CEBPA mRNA
STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]
CTD PMID:24316209 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO cucurbitacin B results in decreased expression of CEBPD CTD PMID:24316209 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:29250925 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO cucurbitacin B results in decreased expression of FABP4 mRNA CTD PMID:24316209 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein] CTD PMID:29250925 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO cucurbitacin B results in increased expression of KLF5 CTD PMID:24316209 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP2 mRNA] CTD PMID:29250925 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
ISO STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of PPARG mRNA] CTD PMID:24316209 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
affects response to substance
ISO [WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B; cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]; cucurbitacin B results in decreased phosphorylation of and results in decreased activity of STAT3 protein; STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]; STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of PPARG mRNA]
STAT3 protein affects the susceptibility to cucurbitacin B
CTD PMID:24316209, PMID:29250925 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:29250925 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:29250925 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
deoxynivalenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
multiple interactions
ISO ABCB1 protein results in decreased susceptibility to deoxynivalenol
deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]
CTD PMID:29174985 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO deoxynivalenol results in decreased expression of ABCC3 mRNA CTD PMID:31863870 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of ABCF1 protein CTD PMID:23352502, PMID:23811945 NCBI chr20:3,309,914...3,322,828
Ensembl chr20:3,309,899...3,322,825
JBrowse link
G Abi1 abl-interactor 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of ABI1 protein CTD PMID:23352502 NCBI chr17:89,951,662...90,033,334
Ensembl chr17:89,951,752...90,033,328
JBrowse link
G Abraxas2 abraxas 2, BRISC complex subunit increases expression ISO deoxynivalenol results in increased expression of ABRAXAS2 mRNA CTD PMID:31863870 NCBI chr 1:204,861,768...204,887,344
Ensembl chr 1:204,861,566...204,887,377
JBrowse link
G Acan aggrecan decreases expression ISO deoxynivalenol results in decreased expression of ACAN mRNA CTD PMID:31863870 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of ACIN1 protein CTD PMID:23811945 NCBI chr15:33,288,369...33,333,256
Ensembl chr15:33,288,374...33,333,417
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle affects phosphorylation ISO deoxynivalenol affects the phosphorylation of ACTA1 protein CTD PMID:23811945 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Actbl2 actin, beta-like 2 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of ACTBL2 protein CTD PMID:23352502 NCBI chr 2:42,829,413...42,832,160
Ensembl chr 2:42,829,413...42,832,160
JBrowse link
G Agfg1 ArfGAP with FG repeats 1 affects phosphorylation
increases expression
ISO deoxynivalenol affects the phosphorylation of AGFG1 protein
deoxynivalenol results in increased expression of AGFG1 mRNA
CTD PMID:23811945, PMID:31863870 NCBI chr 9:88,607,508...88,663,486
Ensembl chr 9:88,607,508...88,662,224
JBrowse link
G Ahnak AHNAK nucleoprotein affects phosphorylation ISO deoxynivalenol affects the phosphorylation of AHNAK protein CTD PMID:23352502, PMID:23811945 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Ak7 adenylate kinase 7 decreases expression ISO deoxynivalenol results in decreased expression of AK7 mRNA CTD PMID:26763390 NCBI chr 6:129,538,648...129,606,960
Ensembl chr 6:129,538,982...129,606,932
JBrowse link
G Akap8l A-kinase anchoring protein 8 like increases expression ISO deoxynivalenol results in increased expression of AKAP8L mRNA CTD PMID:31863870 NCBI chr 7:14,340,168...14,369,835
Ensembl chr 7:14,340,170...14,369,821
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of AKT1 protein; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of AKT1 protein] CTD PMID:15976193, PMID:16424113, PMID:24937323 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin decreases expression
multiple interactions
increases expression
ISO deoxynivalenol results in decreased expression of ALB protein
[deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA
deoxynivalenol results in decreased expression of ALB mRNA; deoxynivalenol results in decreased expression of ALB protein
deoxynivalenol results in increased expression of ALB mRNA
CTD PMID:25445755, PMID:28865950, PMID:28935499 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression ISO deoxynivalenol results in decreased expression of ALDH3B1 mRNA CTD PMID:31863870 NCBI chr 1:219,145,457...219,181,536
Ensembl chr 1:219,145,459...219,186,860
JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of ALDOB mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA
CTD PMID:28865950, PMID:28935499 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase increases expression ISO deoxynivalenol results in increased expression of ALKBH1 mRNA CTD PMID:31863870 NCBI chr 6:111,456,096...111,476,829
Ensembl chr 6:111,456,187...111,477,090
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO deoxynivalenol results in decreased expression of and results in decreased activity of ALPI protein CTD PMID:20362602 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Alpk2 alpha-kinase 2 decreases expression ISO deoxynivalenol results in decreased expression of ALPK2 mRNA CTD PMID:31863870 NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO deoxynivalenol results in decreased expression of AMIGO2 mRNA CTD PMID:31863870 NCBI chr 7:138,704,124...138,707,221
Ensembl chr 7:138,704,126...138,707,221
JBrowse link
G Angptl7 angiopoietin like 7 decreases expression ISO deoxynivalenol results in decreased expression of ANGPTL7 mRNA CTD PMID:31863870 NCBI chr 5:165,311,794...165,318,361
Ensembl chr 5:165,312,130...165,316,652
JBrowse link
G Ankrd13c ankyrin repeat domain 13C increases expression ISO deoxynivalenol results in increased expression of ANKRD13C mRNA CTD PMID:31863870 NCBI chr 2:264,785,379...264,833,283
Ensembl chr 2:264,786,242...264,833,283
JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression ISO deoxynivalenol results in decreased expression of ANKRD37 mRNA CTD PMID:31863870 NCBI chr16:49,463,016...49,465,905
Ensembl chr16:49,462,889...49,465,888
JBrowse link
G Anln anillin, actin binding protein increases expression ISO deoxynivalenol results in increased expression of ANLN mRNA CTD PMID:31863870 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression ISO deoxynivalenol results in decreased expression of ANPEP mRNA CTD PMID:31863870 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Ar androgen receptor decreases activity
multiple interactions
ISO deoxynivalenol results in decreased activity of AR protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein
CTD PMID:27481073 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arglu1 arginine and glutamate rich 1 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of ARGLU1 protein CTD PMID:23811945 NCBI chr16:86,600,877...86,625,084
Ensembl chr16:86,600,877...86,625,083
JBrowse link
G Arhgap45 Rho GTPase activating protein 45 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of ARHGAP45 protein CTD PMID:23811945 NCBI chr 7:12,541,032...12,741,314
Ensembl chr 7:12,541,061...12,741,296
JBrowse link
G Armc10 armadillo repeat containing 10 affects phosphorylation
increases phosphorylation
ISO deoxynivalenol affects the phosphorylation of ARMC10 protein
deoxynivalenol results in increased phosphorylation of ARMC10 protein
CTD PMID:23352502, PMID:23811945 NCBI chr 4:10,004,846...10,020,017
Ensembl chr 4:10,004,848...10,020,022
JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 increases expression ISO deoxynivalenol results in increased expression of ASCC3 mRNA CTD PMID:31863870 NCBI chr20:55,253,670...55,557,249
Ensembl chr20:55,253,686...55,556,473
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 increases expression ISO deoxynivalenol results in increased expression of ASCL2 mRNA CTD PMID:19438726 NCBI chr 1:216,154,002...216,156,409
Ensembl chr 1:216,154,002...216,156,409
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO deoxynivalenol results in decreased expression of ASNS mRNA CTD PMID:31863870 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions
increases phosphorylation
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]
deoxynivalenol results in increased expression of ATF1 mRNA
CTD PMID:16424113, PMID:22846391 NCBI chr 7:141,882,261...141,924,790
Ensembl chr 7:141,882,251...141,924,788
JBrowse link
G Atf2 activating transcription factor 2 increases expression
multiple interactions
increases phosphorylation
affects localization
ISO deoxynivalenol results in increased expression of ATF2 mRNA
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF2 protein]
deoxynivalenol affects the localization of ATF2 protein
CTD PMID:12604842, PMID:15772366, PMID:22846391 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
decreases expression
increases expression
increases response to substance
decreases degradation
ISO [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein]
deoxynivalenol results in decreased expression of ATF3 mRNA
deoxynivalenol results in increased expression of ATF3 mRNA; deoxynivalenol results in increased expression of ATF3 protein; deoxynivalenol results in increased expression of ATF3 protein alternative form
ATF3 protein results in increased susceptibility to deoxynivalenol
deoxynivalenol results in decreased degradation of ATF3 mRNA; deoxynivalenol results in decreased degradation of ATF3 protein
CTD PMID:19101521, PMID:19360757, PMID:21074547, PMID:22003189, PMID:22846391, PMID:23253260, PMID:30286430 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression
ISO ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]
deoxynivalenol results in increased expression of ATF6 protein
deoxynivalenol results in increased expression of ATF6 mRNA
CTD PMID:19336499, PMID:20682335, PMID:22846391 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atg14 autophagy related 14 increases expression ISO deoxynivalenol results in increased expression of ATG14 mRNA CTD PMID:31863870 NCBI chr15:24,343,418...24,374,776
Ensembl chr15:24,343,314...24,374,753
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase increases expression ISO deoxynivalenol results in increased expression of ATG4B mRNA CTD PMID:31863870 NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637
JBrowse link
G Atp10a ATPase phospholipid transporting 10A (putative) decreases expression ISO deoxynivalenol results in decreased expression of ATP10A mRNA CTD PMID:31863870 NCBI chr 1:115,973,343...116,141,892
Ensembl chr 1:115,975,324...116,141,892
JBrowse link
G Atp8b2 ATPase phospholipid transporting 8B2 decreases expression ISO deoxynivalenol results in decreased expression of ATP8B2 mRNA CTD PMID:31863870 NCBI chr 2:189,285,961...189,306,947
Ensembl chr 2:189,285,953...189,307,108
JBrowse link
G Atrx ATRX, chromatin remodeler affects phosphorylation ISO deoxynivalenol affects the phosphorylation of ATRX protein CTD PMID:23811945 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 decreases expression ISO deoxynivalenol results in decreased expression of B3GALT4 mRNA CTD PMID:26763390 NCBI chr20:5,446,104...5,447,679
Ensembl chr20:5,446,104...5,447,673
JBrowse link
G Bach2 BTB domain and CNC homolog 2 increases expression ISO deoxynivalenol results in increased expression of BACH2 mRNA CTD PMID:24247028 NCBI chr 5:47,458,891...47,807,176
Ensembl chr 5:47,546,014...47,807,166
JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of BAD protein CTD PMID:15976193 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO deoxynivalenol results in increased expression of BAG3 mRNA CTD PMID:22846391 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO deoxynivalenol results in increased expression of BAK1 mRNA CTD PMID:20702593 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects localization
decreases expression
ISO Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]
deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA]
deoxynivalenol results in increased expression of BAX mRNA; deoxynivalenol results in increased expression of BAX protein
deoxynivalenol affects the localization of BAX protein
deoxynivalenol results in decreased expression of BAX mRNA
CTD PMID:15976193, PMID:17166419, PMID:19410639, PMID:22269384, PMID:25445755 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO deoxynivalenol results in increased expression of BBC3 mRNA CTD PMID:22846391 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl10 BCL10, immune signaling adaptor increases expression ISO deoxynivalenol results in increased expression of BCL10 mRNA CTD PMID:22846391 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression
ISO Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]
deoxynivalenol promotes the reaction [Aflatoxin B1 results in decreased expression of BCL2 mRNA]
deoxynivalenol results in increased expression of BCL2 mRNA
deoxynivalenol results in decreased expression of BCL2 mRNA; deoxynivalenol results in decreased expression of BCL2 protein
CTD PMID:17166419, PMID:22269384, PMID:25445755 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO deoxynivalenol results in decreased expression of BCL2L1 mRNA CTD PMID:22846391 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l13 BCL2 like 13 increases expression ISO deoxynivalenol results in increased expression of BCL2L13 mRNA CTD PMID:22846391 NCBI chr 4:153,385,200...153,438,096
Ensembl chr 4:153,385,205...153,436,660
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO deoxynivalenol results in increased expression of BCL6 mRNA CTD PMID:22968694, PMID:31863870 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 affects phosphorylation
increases expression
ISO deoxynivalenol affects the phosphorylation of BCLAF1 protein
deoxynivalenol results in increased expression of BCLAF1 mRNA
CTD PMID:22846391, PMID:23352502, PMID:23811945 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Bend7 BEN domain containing 7 increases expression ISO deoxynivalenol results in increased expression of BEND7 mRNA CTD PMID:31863870 NCBI chr17:77,448,430...77,527,888
Ensembl chr17:77,448,430...77,527,894
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO deoxynivalenol results in decreased expression of BID mRNA CTD PMID:22269384 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bin1 bridging integrator 1 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of BIN1 protein CTD PMID:23352502 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO deoxynivalenol results in increased expression of BMP2 mRNA CTD PMID:31863870 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO deoxynivalenol results in increased expression of BNIP1 mRNA CTD PMID:22846391 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of BNIP2 protein CTD PMID:23352502 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Bptf bromodomain PHD finger transcription factor increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of BPTF protein CTD PMID:23352502 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Brd3 bromodomain containing 3 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of BRD3 protein CTD PMID:23811945 NCBI chr 3:5,995,204...6,054,467
Ensembl chr 3:5,997,315...6,054,483
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 decreases expression ISO deoxynivalenol results in decreased expression of BST1 mRNA CTD PMID:31863870 NCBI chr14:71,798,218...71,814,540
Ensembl chr14:71,798,651...71,814,523
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO deoxynivalenol results in increased expression of BUB1B mRNA CTD PMID:31863870 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein increases expression ISO deoxynivalenol results in increased expression of BUB3 mRNA CTD PMID:31863870 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G C3 complement C3 increases expression ISO deoxynivalenol results in increased expression of C3 mRNA CTD PMID:22968694 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression ISO deoxynivalenol results in increased expression of C3AR1 mRNA CTD PMID:12604170, PMID:22968694 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G C4b complement C4B (Chido blood group) increases expression ISO deoxynivalenol results in increased expression of C4B mRNA CTD PMID:22968694 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D increases expression ISO deoxynivalenol results in increased expression of CACNA1D mRNA CTD PMID:23792671 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 decreases expression ISO deoxynivalenol results in decreased expression of CACNG6 mRNA CTD PMID:26763390 NCBI chr 1:64,307,684...64,322,124
Ensembl chr 1:64,305,438...64,321,241
JBrowse link
G Canx calnexin decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of CANX protein CTD PMID:23811945 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Card11 caspase recruitment domain family, member 11 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of CARD11 protein CTD PMID:23811945 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Casc3 CASC3 exon junction complex subunit increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of CASC3 protein CTD PMID:23811945 NCBI chr10:86,724,534...86,744,485
Ensembl chr10:86,724,427...86,745,927
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
increases cleavage
multiple interactions
decreases expression
ISO deoxynivalenol results in increased activity of CASP3 protein
deoxynivalenol results in increased expression of CASP3 mRNA
deoxynivalenol results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [deoxynivalenol results in increased activity of CASP3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; deoxynivalenol results in increased activity of and results in increased cleavage of CASP3 protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; pifithrin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]
deoxynivalenol results in increased expression of CASP3 mRNA; deoxynivalenol results in increased expression of CASP3 protein
deoxynivalenol results in decreased expression of CASP3 protein
[Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]
CTD PMID:15772366, PMID:15976193, PMID:17166419, PMID:19410639, PMID:19664677, PMID:22269384, PMID:22491426, PMID:25445755, PMID:27757495, PMID:30668976 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity ISO deoxynivalenol results in increased activity of CASP7 protein CTD PMID:27757495 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of CASP8 mRNA
[Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA]
deoxynivalenol results in increased activity of and results in increased cleavage of CASP8 protein
CTD PMID:22491426, PMID:22846391, PMID:30668976 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 decreases expression
multiple interactions
increases expression
increases activity
ISO deoxynivalenol results in decreased expression of CASP9 protein
Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA]
deoxynivalenol results in increased activity of and results in increased cleavage of CASP9 protein
deoxynivalenol results in increased expression of CASP9 mRNA; deoxynivalenol results in increased expression of CASP9 protein
deoxynivalenol results in increased activity of CASP9 protein
CTD PMID:22269384, PMID:22491426, PMID:30668976 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor multiple interactions ISO CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein] CTD PMID:25787141 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of CAT protein
Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein]
CTD PMID:20347963 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbll1 Cbl proto-oncogene like 1 increases expression ISO deoxynivalenol results in increased expression of CBLL1 mRNA CTD PMID:31863870 NCBI chr 6:50,772,718...50,786,861
Ensembl chr 6:50,772,829...50,786,967
JBrowse link
G Cbs cystathionine beta synthase decreases expression ISO deoxynivalenol results in decreased expression of CBS mRNA CTD PMID:31863870 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Cbx5 chromobox 5 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of CBX5 protein CTD PMID:23811945 NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
JBrowse link
G Ccdc112 coiled-coil domain containing 112 increases expression ISO deoxynivalenol results in increased expression of CCDC112 mRNA CTD PMID:31863870 NCBI chr18:40,220,855...40,254,845
Ensembl chr18:40,220,855...40,254,845
JBrowse link
G Cck cholecystokinin increases secretion
multiple interactions
increases expression
ISO deoxynivalenol results in increased secretion of CCK protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; [N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine co-treated with Ruthenium Red] inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; TRPA1 affects the reaction [deoxynivalenol results in increased secretion of CCK protein]
CTD PMID:22903826, PMID:24385417, PMID:25787141, PMID:26979077 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases expression ISO deoxynivalenol results in increased expression of CCL1 mRNA CTD PMID:22968694 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO deoxynivalenol results in increased expression of CCL11 mRNA CTD PMID:22968694 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO deoxynivalenol results in increased expression of CCL12 mRNA CTD PMID:22968694 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO deoxynivalenol results in increased expression of CCL17 mRNA CTD PMID:22968694 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of CCL2 mRNA; deoxynivalenol results in increased expression of CCL2 protein
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL2 mRNA]
CTD PMID:15371230, PMID:15681167, PMID:17090620, PMID:22846391, PMID:22968694, PMID:24793808 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO deoxynivalenol results in increased expression of CCL20 mRNA CTD PMID:27757495 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression ISO deoxynivalenol results in increased expression of CCL22 mRNA CTD PMID:22968694 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 increases expression ISO deoxynivalenol results in increased expression of CCL24 mRNA CTD PMID:22968694 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 decreases expression ISO deoxynivalenol results in decreased expression of CCL25 mRNA CTD PMID:22968694 NCBI chr12:2,429,492...2,438,928
Ensembl chr12:2,429,509...2,438,817
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO deoxynivalenol results in increased expression of CCL3 mRNA CTD PMID:22846391, PMID:22968694 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO deoxynivalenol results in increased expression of CCL4 mRNA CTD PMID:21074547, PMID:22846391, PMID:22968694, PMID:27757495 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO deoxynivalenol results in increased expression of CCL5 mRNA CTD PMID:22968694, PMID:27757495 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions
increases expression
ISO Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL7 mRNA] CTD PMID:15371230, PMID:15681167, PMID:22968694, PMID:24793808 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO deoxynivalenol results in increased expression of CCN1 mRNA CTD PMID:15371230 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of CCND1 mRNA; deoxynivalenol results in increased expression of CCND1 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of CCND1 protein]
CTD PMID:22454431, PMID:24937323, PMID:32416088 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO deoxynivalenol results in decreased expression of CCNE1 mRNA CTD PMID:27456127 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccng2 cyclin G2 increases expression ISO deoxynivalenol results in increased expression of CCNG2 mRNA CTD PMID:30169763 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccny cyclin Y affects phosphorylation ISO deoxynivalenol affects the phosphorylation of CCNY protein CTD PMID:23811945 NCBI chr17:62,332,537...62,462,644
Ensembl chr17:62,332,537...62,462,644
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO deoxynivalenol results in increased expression of CCR1 mRNA CTD PMID:22968694 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO deoxynivalenol results in increased expression of CCR2 mRNA CTD PMID:22968694
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO deoxynivalenol results in increased expression of CCR3 mRNA CTD PMID:22968694 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression ISO deoxynivalenol results in increased expression of CCR4 mRNA CTD PMID:27757495 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO deoxynivalenol results in increased expression of CCR7 mRNA CTD PMID:22968694 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cd14 CD14 molecule multiple interactions ISO deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein] CTD PMID:19549553 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd248 CD248 molecule decreases expression ISO deoxynivalenol results in decreased expression of CD248 mRNA CTD PMID:31863870 NCBI chr 1:220,353,308...220,355,872
Ensembl chr 1:220,446,425...220,448,989
JBrowse link
G Cd40 CD40 molecule decreases expression ISO deoxynivalenol results in decreased expression of CD40 mRNA CTD PMID:22968694 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO deoxynivalenol results in increased expression of CD55 mRNA CTD PMID:22846391, PMID:24247028 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd68 Cd68 molecule increases expression ISO deoxynivalenol results in increased expression of CD68 mRNA CTD PMID:25549547 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd69 Cd69 molecule increases expression ISO deoxynivalenol results in increased expression of CD69 mRNA CTD PMID:22846391, PMID:24247028 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd80 Cd80 molecule increases expression ISO deoxynivalenol results in increased expression of CD80 mRNA CTD PMID:21074547 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule increases expression ISO deoxynivalenol results in increased expression of CD86 mRNA CTD PMID:21074547 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdan1 codanin 1 increases expression ISO deoxynivalenol results in increased expression of CDAN1 mRNA CTD PMID:31863870 NCBI chr 3:112,660,839...112,676,596
Ensembl chr 3:112,663,383...112,676,556
JBrowse link
G Cdh13 cadherin 13 decreases expression ISO deoxynivalenol results in decreased expression of CDH13 mRNA CTD PMID:31863870 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO deoxynivalenol results in increased expression of CDK1 mRNA CTD PMID:31863870 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
decreases degradation
ISO deoxynivalenol results in increased expression of CDKN1A mRNA; deoxynivalenol results in increased expression of CDKN1A protein
EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [deoxynivalenol results in decreased degradation of CDKN1A mRNA]
CTD PMID:18006205, PMID:22454431, PMID:30169763, PMID:30286430, PMID:31863870 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO deoxynivalenol results in increased expression of CDKN3 mRNA CTD PMID:31863870 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
decreases expression
ISO [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA
deoxynivalenol results in decreased expression of CEBPA mRNA
CTD PMID:28865950, PMID:28935499 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases activity
affects localization
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CEBPB protein]
deoxynivalenol affects the localization of CEBPB protein
CTD PMID:12604842, PMID:15772366 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cenpw centromere protein W increases expression ISO deoxynivalenol results in increased expression of CENPW mRNA CTD PMID:31863870 NCBI chr 1:29,915,443...29,920,598
Ensembl chr 1:29,915,443...29,920,598
JBrowse link
G Cercam cerebral endothelial cell adhesion molecule decreases expression ISO deoxynivalenol results in decreased expression of CERCAM mRNA CTD PMID:31863870 NCBI chr 3:8,421,116...8,444,743
Ensembl chr 3:8,430,829...8,444,851
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 decreases expression ISO deoxynivalenol results in decreased expression of CGREF1 mRNA CTD PMID:31863870 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO deoxynivalenol results in decreased expression of CHAC1 mRNA CTD PMID:23253260 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of CHAMP1 protein CTD PMID:23352502 NCBI chr16:80,839,373...80,850,340
Ensembl chr16:80,839,374...80,850,340
JBrowse link
G Chka choline kinase alpha increases expression ISO deoxynivalenol results in increased expression of CHKA mRNA CTD PMID:31863870 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Chn1 chimerin 1 decreases expression ISO deoxynivalenol results in decreased expression of CHN1 mRNA CTD PMID:31863870 NCBI chr 3:60,512,360...60,668,413
Ensembl chr 3:60,513,077...60,611,924
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO deoxynivalenol results in increased expression of CHORDC1 mRNA CTD PMID:31863870 NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of CHUK protein CTD PMID:20633634 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO deoxynivalenol results in increased expression of CISH mRNA CTD PMID:19625342 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO deoxynivalenol results in increased expression of CKAP2 mRNA CTD PMID:31863870 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO deoxynivalenol results in increased expression of CKAP5 mRNA CTD PMID:31863870 NCBI chr 3:80,424,320...80,526,583
Ensembl chr 3:80,468,154...80,526,593
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression ISO deoxynivalenol results in increased expression of CKS1B mRNA CTD PMID:31863870 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Cldn1 claudin 1 increases expression
decreases expression
multiple interactions
affects expression
ISO deoxynivalenol results in increased expression of CLDN1 mRNA
deoxynivalenol results in decreased expression of CLDN1 protein
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein; deoxynivalenol results in decreased expression of and affects the localization of CLDN1 protein
deoxynivalenol affects the expression of CLDN1 protein
CTD PMID:24568843, PMID:28865950, PMID:28935499 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn2 claudin 2 affects expression
increases expression
ISO deoxynivalenol affects the expression of CLDN2 protein
deoxynivalenol results in increased expression of CLDN2 mRNA
CTD PMID:24568843 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cldn3 claudin 3 multiple interactions
increases expression
affects expression
ISO deoxynivalenol results in decreased expression of and affects the localization of CLDN3 protein
[deoxynivalenol results in increased susceptibility to Antigens] which results in decreased expression of CLDN3 mRNA
deoxynivalenol results in increased expression of CLDN3 mRNA
deoxynivalenol affects the expression of CLDN3 protein
CTD PMID:24568843, PMID:28935500 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn4 claudin 4 decreases expression
increases expression
multiple interactions
ISO deoxynivalenol results in decreased expression of CLDN4 protein
deoxynivalenol results in increased expression of CLDN4 mRNA
deoxynivalenol results in decreased expression of and affects the localization of CLDN4 protein
CTD PMID:19289138, PMID:20362602, PMID:24568843 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clic3 chloride intracellular channel 3 decreases expression ISO deoxynivalenol results in decreased expression of CLIC3 mRNA CTD PMID:31863870 NCBI chr 3:2,675,732...2,678,248
Ensembl chr 3:2,676,296...2,680,565
JBrowse link
G Cnpy2 canopy FGF signaling regulator 2 decreases expression ISO deoxynivalenol results in decreased expression of CNPY2 mRNA CTD PMID:31863870 NCBI chr 7:2,737,674...2,744,321
Ensembl chr 7:2,737,765...2,742,369
JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO deoxynivalenol results in decreased expression of COL15A1 mRNA CTD PMID:31863870 NCBI chr 5:62,840,360...62,950,240 JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO deoxynivalenol results in decreased expression of COL4A1 mRNA CTD PMID:31863870 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO deoxynivalenol results in decreased expression of COL5A1 mRNA CTD PMID:31863870 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col6a2 collagen type VI alpha 2 chain decreases expression ISO deoxynivalenol results in decreased expression of COL6A2 mRNA CTD PMID:31863870 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Comt catechol-O-methyltransferase decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of COMT protein CTD PMID:23811945 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Coro1a coronin 1A affects phosphorylation ISO deoxynivalenol affects the phosphorylation of CORO1A protein CTD PMID:23811945 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Coro2b coronin 2B decreases expression ISO deoxynivalenol results in decreased expression of CORO2B mRNA CTD PMID:31863870 NCBI chr 8:67,374,617...67,492,490
Ensembl chr 8:67,376,294...67,492,037
JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 increases expression ISO deoxynivalenol results in increased expression of CPSF2 mRNA CTD PMID:31863870 NCBI chr 6:125,870,372...125,898,039
Ensembl chr 6:125,870,372...125,898,874
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
increases activity
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased activity of CREB1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]
deoxynivalenol affects the localization of CREB1 protein
CTD PMID:12604842, PMID:16424113, PMID:32416088 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb5 cAMP responsive element binding protein 5 increases expression ISO deoxynivalenol results in increased expression of CREB5 mRNA CTD PMID:31863870 NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351
JBrowse link
G Crebbp CREB binding protein increases expression ISO deoxynivalenol results in increased expression of CREBBP mRNA CTD PMID:24247028 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 decreases expression ISO deoxynivalenol results in decreased expression of CRELD1 mRNA CTD PMID:31863870 NCBI chr 4:145,440,284...145,449,894
Ensembl chr 4:145,440,114...145,449,892
JBrowse link
G Crp C-reactive protein increases expression ISO deoxynivalenol results in increased expression of CRP mRNA CTD PMID:22968694 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO deoxynivalenol results in increased expression of CSF3 mRNA CTD PMID:27757495 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 decreases expression ISO deoxynivalenol results in decreased expression of CTHRC1 mRNA CTD PMID:31863870 NCBI chr 7:77,966,722...77,977,004
Ensembl chr 7:77,966,722...77,977,004
JBrowse link
G Ctnnb1 catenin beta 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of CTNNB1 protein CTD PMID:23811945 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctso cathepsin O decreases expression ISO deoxynivalenol results in decreased expression of CTSO mRNA CTD PMID:31863870 NCBI chr 2:180,857,178...180,881,677 JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 increases expression ISO deoxynivalenol results in increased expression of CWF19L2 mRNA CTD PMID:31863870 NCBI chr 6:18,970,616...19,037,176
Ensembl chr 6:18,970,564...19,055,924
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO deoxynivalenol results in increased expression of CX3CL1 mRNA CTD PMID:22846391 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression
ISO [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA] CTD PMID:22003189, PMID:27757495 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression
ISO deoxynivalenol results in decreased expression of CXCL10 mRNA
deoxynivalenol results in increased expression of CXCL10 mRNA
CTD PMID:15371230, PMID:22968694 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 decreases expression
increases expression
ISO deoxynivalenol results in decreased expression of CXCL11 mRNA
deoxynivalenol results in increased expression of CXCL11 mRNA
CTD PMID:22968694, PMID:27757495 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of CXCL2 mRNA; deoxynivalenol results in increased expression of CXCL2 protein
deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CXCL2 mRNA]
CTD PMID:12604170, PMID:15371230, PMID:15681167, PMID:22968694, PMID:24793808, PMID:27757495 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]
deoxynivalenol results in increased expression of CXCL1 mRNA; deoxynivalenol results in increased expression of CXCL3 mRNA
CTD PMID:15371230, PMID:15681167, PMID:22003189, PMID:22968694, PMID:27757495 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO deoxynivalenol results in increased expression of CXCL9 mRNA CTD PMID:22968694 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO deoxynivalenol results in increased expression of CXCR1 mRNA CTD PMID:22968694 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression ISO deoxynivalenol results in increased expression of CXCR2 mRNA CTD PMID:22968694 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO deoxynivalenol results in increased expression of CXCR4 mRNA CTD PMID:22846391, PMID:27757495 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression
decreases expression
increases activity
ISO deoxynivalenol affects the localization of CYCS protein
deoxynivalenol results in increased expression of CYCS mRNA; deoxynivalenol results in increased expression of CYCS protein
deoxynivalenol results in decreased expression of CYCS protein
deoxynivalenol results in increased activity of CYCS protein
CTD PMID:15976193, PMID:22269384, PMID:22846391 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases expression ISO deoxynivalenol results in increased expression of CYP11B1 mRNA CTD PMID:22982764 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression ISO deoxynivalenol results in increased expression of CYP11B2 mRNA CTD PMID:22982764 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO deoxynivalenol results in increased expression of CYP17A1 mRNA CTD PMID:22982764 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO deoxynivalenol results in decreased expression of CYP19A1 mRNA CTD PMID:22982764 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO deoxynivalenol results in increased expression of CYP1A1 mRNA CTD PMID:22982764 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO deoxynivalenol results in decreased expression of CYP1B1 mRNA CTD PMID:20702593 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 multiple interactions ISO [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA CTD PMID:28865950, PMID:28935499 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cytl1 cytokine like 1 decreases expression ISO deoxynivalenol results in decreased expression of CYTL1 mRNA CTD PMID:31863870 NCBI chr14:77,805,137...77,810,147
Ensembl chr14:77,805,130...77,810,147
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO deoxynivalenol results in increased expression of DDB2 mRNA CTD PMID:31863870 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
decreases expression
ISO deoxynivalenol results in increased expression of DDIT3 mRNA
deoxynivalenol results in decreased expression of DDIT3 mRNA
CTD PMID:22846391, PMID:23253260, PMID:30169763 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO deoxynivalenol results in decreased expression of DDIT4 mRNA CTD PMID:31863870 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx21 DExD-box helicase 21 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of DDX21 protein CTD PMID:23352502, PMID:23811945 NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632
JBrowse link
G Ddx39a DExD-box helicase 39A increases expression ISO deoxynivalenol results in increased expression of DDX39A mRNA CTD PMID:31863870 NCBI chr19:24,846,530...24,854,886
Ensembl chr19:24,846,938...24,854,953
JBrowse link
G Ddx52 DExD-box helicase 52 increases expression ISO deoxynivalenol results in increased expression of DDX52 mRNA CTD PMID:31863870 NCBI chr10:71,253,667...71,276,397
Ensembl chr10:71,253,598...71,277,277
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO deoxynivalenol results in decreased expression of DEPTOR mRNA CTD PMID:31863870 NCBI chr 7:94,795,161...95,000,750
Ensembl chr 7:94,795,214...94,995,809
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of DFFA protein CTD PMID:23811945 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of DKC1 protein CTD PMID:23811945 NCBI chr  X:155,844,914...155,862,363
Ensembl chr  X:155,844,857...155,862,475
JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of DNAH10 protein CTD PMID:23811945 NCBI chr12:37,237,482...37,365,258 JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO deoxynivalenol results in increased expression of DNAJA1 mRNA CTD PMID:15371230 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 increases expression ISO deoxynivalenol results in increased expression of DNAJC1 mRNA CTD PMID:24247028 NCBI chr17:84,986,994...85,141,464
Ensembl chr17:84,986,991...85,141,210
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
decreases expression
ISO deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA]
deoxynivalenol results in decreased expression of DNAJC3 mRNA
CTD PMID:10652249 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of DNAJC5 protein CTD PMID:23352502 NCBI chr 3:177,012,714...177,047,787
Ensembl chr 3:177,013,604...177,043,902
JBrowse link
G Dnmt1 DNA methyltransferase 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of DNMT1 protein CTD PMID:23352502, PMID:23811945 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 increases expression ISO deoxynivalenol results in increased expression of DNTTIP2 mRNA CTD PMID:31863870 NCBI chr 2:225,854,618...225,867,103
Ensembl chr 2:225,854,629...225,866,357
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of DUSP1 mRNA; deoxynivalenol results in increased expression of DUSP1 protein
Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of DUSP1 mRNA]
[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein
CTD PMID:15371230, PMID:15681167, PMID:20708668 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO deoxynivalenol results in decreased expression of DUSP6 mRNA CTD PMID:24247028 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO deoxynivalenol results in increased expression of DUSP8 mRNA CTD PMID:23792671 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of DYNC1LI1 protein CTD PMID:23352502 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Ecm1 extracellular matrix protein 1 decreases expression ISO deoxynivalenol results in decreased expression of ECM1 mRNA CTD PMID:31863870 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Ect2 epithelial cell transforming 2 increases expression ISO deoxynivalenol results in increased expression of ECT2 mRNA CTD PMID:31863870 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of EEF1B2 protein CTD PMID:23352502 NCBI chr 9:69,953,440...69,956,158
Ensembl chr 9:69,953,440...69,956,160
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of EEF1D protein CTD PMID:23811945 NCBI chr 7:116,928,264...116,942,981
Ensembl chr 7:116,928,265...116,936,674
JBrowse link
G Egf epidermal growth factor increases expression ISO deoxynivalenol results in increased expression of EGF mRNA CTD PMID:27757495 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO [deoxynivalenol results in increased expression of EGR1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased expression of EGR1 mRNA; deoxynivalenol results in increased expression of EGR1 protein
ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; deoxynivalenol results in increased expression of and results in increased phosphorylation of EGR1 protein; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
CTD PMID:17707346, PMID:18485432, PMID:19360757, PMID:30286430 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 increases expression ISO deoxynivalenol results in increased expression of EID2 mRNA CTD PMID:31863870 NCBI chr 1:85,515,610...85,517,516
Ensembl chr 1:85,516,653...85,517,360
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of EIF2A protein CTD PMID:20682335 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression
affects response to substance
multiple interactions
ISO deoxynivalenol results in decreased expression of EIF2AK2 mRNA
EIF2AK2 protein affects the susceptibility to deoxynivalenol
EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]
CTD PMID:17090620, PMID:18599499, PMID:22491426 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta increases expression ISO deoxynivalenol results in increased expression of EIF2B4 mRNA CTD PMID:31863870 NCBI chr 6:26,546,917...26,552,474
Ensembl chr 6:26,546,924...26,552,430
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta affects expression ISO deoxynivalenol affects the expression of EIF2S2 mRNA CTD PMID:24247028 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects phosphorylation ISO deoxynivalenol affects the phosphorylation of EIF3B protein CTD PMID:23811945 NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C affects phosphorylation ISO deoxynivalenol affects the phosphorylation of EIF3C protein CTD PMID:23811945 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of EIF4EBP1 protein CTD PMID:23352502 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of EIF4G1 protein CTD PMID:23352502 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B affects phosphorylation ISO deoxynivalenol affects the phosphorylation of EIF5B protein CTD PMID:23811945 NCBI chr 9:44,658,724...44,713,518
Ensembl chr 9:44,681,494...44,713,199
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions ISO [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [deoxynivalenol results in increased expression of ELAVL1 protein] which results in decreased degradation of CXCL8 mRNA; deoxynivalenol results in increased expression of and results in increased localization of ELAVL1 protein; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 protein] CTD PMID:19591856, PMID:22003189 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432
JBrowse link
G Emc10 ER membrane protein complex subunit 10 decreases expression ISO deoxynivalenol results in decreased expression of EMC10 mRNA CTD PMID:31863870 NCBI chr 1:100,495,112...100,501,468
Ensembl chr 1:100,495,119...100,501,437
JBrowse link
G Emilin1 elastin microfibril interfacer 1 decreases expression ISO deoxynivalenol results in decreased expression of EMILIN1 mRNA CTD PMID:31863870 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Eng endoglin decreases expression ISO deoxynivalenol results in decreased expression of ENG mRNA CTD PMID:31863870 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Engase endo-beta-N-acetylglucosaminidase increases expression ISO deoxynivalenol results in increased expression of ENGASE mRNA CTD PMID:23792671 NCBI chr10:107,502,636...107,515,300
Ensembl chr10:107,502,695...107,515,371
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
increases expression
ISO EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]
deoxynivalenol results in increased expression of EP300 protein
CTD PMID:30286430 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Ep400 E1A binding protein p400 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of EP400 protein CTD PMID:23352502 NCBI chr12:51,948,650...52,055,274
Ensembl chr12:51,948,650...52,055,271
JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of EPB41L2 protein CTD PMID:23811945 NCBI chr 1:20,881,820...21,067,713
Ensembl chr 1:20,893,995...20,962,526
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO deoxynivalenol results in decreased expression of EPHX1 mRNA CTD PMID:15371230 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression
increases expression
ISO deoxynivalenol results in decreased expression of ERN1 mRNA
deoxynivalenol results in increased expression of ERN1 protein
CTD PMID:19336499, PMID:20682335 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Etnk1 ethanolamine kinase 1 increases expression ISO deoxynivalenol results in increased expression of ETNK1 mRNA CTD PMID:31863870 NCBI chr 4:177,402,904...177,447,047
Ensembl chr 4:177,402,904...177,447,028
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO deoxynivalenol results in increased expression of EVI2A mRNA CTD PMID:24247028 NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
JBrowse link
G Evl Enah/Vasp-like affects phosphorylation ISO deoxynivalenol affects the phosphorylation of EVL protein CTD PMID:23811945 NCBI chr 6:132,470,283...132,590,242
Ensembl chr 6:132,510,757...132,590,241
JBrowse link
G Exosc2 exosome component 2 increases expression ISO deoxynivalenol results in increased expression of EXOSC2 mRNA CTD PMID:24247028 NCBI chr 3:10,151,734...10,161,997
Ensembl chr 3:10,151,284...10,161,989
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO deoxynivalenol results in decreased expression of F3 mRNA CTD PMID:31863870 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp3 fatty acid binding protein 3 decreases expression ISO deoxynivalenol results in decreased expression of FABP3 mRNA CTD PMID:31863870 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO deoxynivalenol results in decreased expression of FABP4 mRNA CTD PMID:31863870 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fam83d family with sequence similarity 83, member D increases expression ISO deoxynivalenol results in increased expression of FAM83D mRNA CTD PMID:31863870 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
EXP Bentonite inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]
deoxynivalenol results in increased expression of FAS mRNA
CTD PMID:26115597 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO deoxynivalenol results in increased expression of FASL mRNA CTD PMID:22968694 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fastkd2 FAST kinase domains 2 increases expression ISO deoxynivalenol results in increased expression of FASTKD2 mRNA CTD PMID:31863870 NCBI chr 9:70,448,386...70,471,420
Ensembl chr 9:70,450,444...70,470,550
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO deoxynivalenol results in increased expression of FBXO22 mRNA CTD PMID:31863870 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fbxo28 F-box protein 28 increases expression ISO deoxynivalenol results in increased expression of FBXO28 mRNA CTD PMID:31863870 NCBI chr13:100,715,257...100,740,728
Ensembl chr13:100,715,260...100,740,728
JBrowse link
G Flna filamin A decreases phosphorylation
increases phosphorylation
ISO deoxynivalenol results in decreased phosphorylation of FLNA protein
deoxynivalenol results in increased phosphorylation of FLNA protein
CTD PMID:23811945 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Fmnl1 formin-like 1 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of FMNL1 protein CTD PMID:23352502 NCBI chr10:91,253,757...91,281,422
Ensembl chr10:91,254,058...91,281,418
JBrowse link
G Fmod fibromodulin decreases expression ISO deoxynivalenol results in decreased expression of FMOD mRNA CTD PMID:31863870 NCBI chr13:50,874,886...50,885,503
Ensembl chr13:50,873,605...50,885,563
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO deoxynivalenol results in decreased expression of FN1 mRNA CTD PMID:31863870 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fnbp1 formin binding protein 1 decreases expression ISO deoxynivalenol results in decreased expression of FNBP1 mRNA CTD PMID:24247028 NCBI chr 3:9,865,657...9,936,333
Ensembl chr 3:9,861,237...9,936,405
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
affects activity
ISO deoxynivalenol results in increased expression of FOS mRNA
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of FOS protein]
deoxynivalenol affects the activity of FOS protein
deoxynivalenol results in increased expression of FOS mRNA; deoxynivalenol results in increased expression of FOS protein
CTD PMID:10662601, PMID:15371230, PMID:15681167, PMID:19360757, PMID:21873375, PMID:22968694, PMID:24937323, PMID:32416088 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit affects activity ISO deoxynivalenol affects the activity of FOSB protein CTD PMID:10662601 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions
increases expression
affects activity
ISO Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of FOSL2 mRNA]
deoxynivalenol affects the activity of FOSL2 protein
CTD PMID:10662601, PMID:15371230, PMID:15681167 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of FOXO1 protein CTD PMID:15976193 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxp3 forkhead box P3 increases expression ISO deoxynivalenol results in increased expression of FOXP3 mRNA CTD PMID:27757495 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fuca1 alpha-L-fucosidase 1 decreases expression ISO deoxynivalenol results in decreased expression of FUCA1 mRNA CTD PMID:31863870 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO deoxynivalenol results in decreased expression of FUT1 mRNA CTD PMID:26763390 NCBI chr 1:101,599,018...101,602,440
Ensembl chr 1:101,599,018...101,602,436
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 decreases phosphorylation
increases phosphorylation
ISO deoxynivalenol results in decreased phosphorylation of G3BP1 protein
deoxynivalenol results in increased phosphorylation of G3BP1 protein
CTD PMID:23352502, PMID:23811945 NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of G3BP2 protein CTD PMID:23352502 NCBI chr14:17,437,145...17,523,254
Ensembl chr14:17,492,081...17,520,792
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO deoxynivalenol results in increased expression of GADD45A mRNA CTD PMID:30169763, PMID:31863870 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO deoxynivalenol results in decreased expression of GALNT1 mRNA CTD PMID:31863870 NCBI chr18:16,141,062...16,187,271
Ensembl chr18:16,146,447...16,185,496
JBrowse link
G Gatad2a GATA zinc finger domain containing 2A affects phosphorylation ISO deoxynivalenol affects the phosphorylation of GATAD2A protein CTD PMID:23352502 NCBI chr16:21,177,793...21,267,768
Ensembl chr16:21,178,138...21,268,504
JBrowse link
G Gcg glucagon multiple interactions
increases expression
increases secretion
ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]
deoxynivalenol results in increased expression of GCG protein
CTD PMID:25787141, PMID:28633506 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gdf5 growth differentiation factor 5 increases expression ISO deoxynivalenol results in increased expression of GDF5 mRNA CTD PMID:31863870 NCBI chr 3:151,482,672...151,487,129
Ensembl chr 3:151,483,249...151,486,693
JBrowse link
G Gh1 growth hormone 1 multiple interactions
decreases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; deoxynivalenol results in decreased expression of and results in decreased secretion of GH1 protein; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein] CTD PMID:26141394 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gip gastric inhibitory polypeptide increases expression ISO deoxynivalenol results in increased expression of GIP protein CTD PMID:28633506 NCBI chr10:83,835,080...83,848,399
Ensembl chr10:83,840,303...83,848,396
JBrowse link
G Gkap1 G kinase anchoring protein 1 increases expression ISO deoxynivalenol results in increased expression of GKAP1 mRNA CTD PMID:31863870 NCBI chr17:6,785,428...6,825,145
Ensembl chr17:6,785,428...6,825,144
JBrowse link
G Gldn gliomedin decreases expression ISO deoxynivalenol results in decreased expression of GLDN mRNA CTD PMID:31863870 NCBI chr 8:58,870,516...58,914,605
Ensembl chr 8:58,870,516...58,914,603
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta affects phosphorylation ISO deoxynivalenol affects the phosphorylation of GP1BB protein CTD PMID:23811945 NCBI chr11:86,520,992...86,522,169
Ensembl chr11:86,520,992...86,522,169
JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO deoxynivalenol results in increased expression of GPKOW mRNA CTD PMID:31863870 NCBI chr  X:15,636,567...15,651,332
Ensembl chr  X:15,636,563...15,651,332
JBrowse link
G Gpn1 GPN-loop GTPase 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of GPN1 protein CTD PMID:23352502 NCBI chr 6:26,255,081...26,272,755
Ensembl chr 6:26,242,925...26,272,808
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
increases activity
ISO
EXP
deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased activity of GPT protein]
Bentonite inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]
deoxynivalenol results in increased activity of GPT protein
CTD PMID:25445755, PMID:26115597 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of GPX1 protein CTD PMID:23811945 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist decreases expression ISO deoxynivalenol results in decreased expression of GREM1 mRNA CTD PMID:31863870 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of GSK3B protein CTD PMID:15976193 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G H1f0 H1 histone family, member 0 increases expression ISO deoxynivalenol results in increased expression of H1-0 mRNA CTD PMID:31863870 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G H1f10 H1.10 linker histone increases expression ISO deoxynivalenol results in increased expression of H1-10 mRNA CTD PMID:31863870 NCBI chr 4:119,889,016...119,892,661
Ensembl chr 4:119,889,371...119,889,949
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO deoxynivalenol results in increased expression of H1-2 mRNA CTD PMID:31863870 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of H1F5 protein CTD PMID:23352502 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression ISO deoxynivalenol results in decreased expression of HAPLN1 mRNA CTD PMID:31863870 NCBI chr 2:18,354,542...18,419,077
Ensembl chr 2:18,354,542...18,419,071
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of HBA protein CTD PMID:23811945 NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
JBrowse link
G Hbb hemoglobin subunit beta affects phosphorylation ISO deoxynivalenol affects the phosphorylation of HBB-B1 protein CTD PMID:23811945 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase increases phosphorylation
affects response to substance
multiple interactions
ISO deoxynivalenol results in increased phosphorylation of HCK protein
HCK protein affects the susceptibility to deoxynivalenol
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; HCK protein affects the reaction [deoxynivalenol results in increased expression of TNF protein]
CTD PMID:15772366, PMID:20181660, PMID:22491426 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
JBrowse link
G Hdac1 histone deacetylase 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of HDAC1 protein CTD PMID:23352502 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of HDAC2 protein CTD PMID:23352502 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdgf heparin binding growth factor decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of HDGF protein CTD PMID:23811945 NCBI chr 2:187,274,898...187,284,670
Ensembl chr 2:187,275,120...187,284,281
JBrowse link
G Hemgn hemogen affects phosphorylation ISO deoxynivalenol affects the phosphorylation of HEMGN protein CTD PMID:23811945 NCBI chr 5:62,004,271...62,025,075
Ensembl chr 5:62,005,071...62,025,152
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression ISO deoxynivalenol results in decreased expression of HINT1 mRNA CTD PMID:15371230 NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO deoxynivalenol results in increased expression of H2BC5 mRNA CTD PMID:31863870 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
JBrowse link
G Hlx H2.0-like homeobox increases expression ISO deoxynivalenol results in increased expression of HLX mRNA CTD PMID:31863870 NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO deoxynivalenol results in decreased expression of HMGCR mRNA CTD PMID:22982764 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
decreases response to substance
increases expression
ISO deoxynivalenol results in decreased expression of HMOX1 mRNA
HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]
HMOX1 protein results in decreased susceptibility to deoxynivalenol
deoxynivalenol results in increased expression of HMOX1 mRNA; deoxynivalenol results in increased expression of HMOX1 protein
CTD PMID:24355168, PMID:26763390, PMID:31034930, PMID:31863870 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of HNF4A mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA
CTD PMID:28865950 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hoxa7 homeobox A7 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of HOXA7 mRNA
AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of HOXA7 mRNA]
CTD PMID:19438726 NCBI chr 4:82,184,299...82,187,890
Ensembl chr 4:82,183,196...82,186,190
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO deoxynivalenol results in increased expression of HSD3B2 mRNA CTD PMID:22982764 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of HSP90AB1 protein CTD PMID:23811945 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases phosphorylation
decreases expression
ISO calpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein]; deoxynivalenol results in increased degradation of and results in decreased expression of HSPA5 protein; phenylalanyl-glycyl-NHO-Bz inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]
deoxynivalenol results in increased phosphorylation of HSPA5 protein
deoxynivalenol results in decreased expression of HSPA5 mRNA
CTD PMID:10652249, PMID:19336499, PMID:20682335, PMID:23811945, PMID:24356939 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of HSPA8 protein CTD PMID:23811945 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of HSPH1 protein CTD PMID:23352502 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated increases expression ISO deoxynivalenol results in increased expression of HYLS1 mRNA CTD PMID:31863870 NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of ICAM1 mRNA
deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]
CTD PMID:19549553, PMID:21074547 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO deoxynivalenol results in decreased expression of ID1 mRNA CTD PMID:31863870 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 decreases expression ISO deoxynivalenol results in decreased expression of IFNAR1 mRNA CTD PMID:17090620 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases expression
ISO deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]
deoxynivalenol results in increased expression of IFNB1 mRNA
CTD PMID:14644621, PMID:17090620, PMID:19857559 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma affects expression
multiple interactions
increases expression
ISO deoxynivalenol affects the expression of IFNG mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]
deoxynivalenol results in increased expression of IFNG mRNA; deoxynivalenol results in increased expression of IFNG protein
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IFNG protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IFNG protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]
CTD PMID:9194413, PMID:9707511, PMID:14644621, PMID:17090620, PMID:17166736, PMID:19549553, PMID:20702593, PMID:22968694, PMID:24937323, PMID:25766886, PMID:28935500, PMID:32416088 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions
decreases expression
ISO deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein]
deoxynivalenol results in decreased expression of IFNGR1 mRNA
CTD PMID:17090620, PMID:19549553 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
ISO deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGF1 mRNA]
deoxynivalenol results in decreased expression of IGF1 protein
CTD PMID:19805407 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression
multiple interactions
ISO deoxynivalenol results in decreased expression of IGFALS mRNA; deoxynivalenol results in decreased expression of IGFALS protein
deoxynivalenol inhibits the reaction [Glutathione results in increased expression of IGFALS mRNA]
CTD PMID:19625342, PMID:19805407, PMID:23298694 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGFBP3 mRNA] CTD PMID:19805407 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression ISO deoxynivalenol results in decreased expression of IGFBP6 mRNA CTD PMID:31863870 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Il10 interleukin 10 increases expression ISO deoxynivalenol results in increased expression of IL10 mRNA CTD PMID:9194413, PMID:9707511, PMID:22968694 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO deoxynivalenol results in increased expression of IL10RB mRNA CTD PMID:22968694 NCBI chr11:31,560,301...31,582,457
Ensembl chr11:31,560,530...31,582,457
JBrowse link
G Il11 interleukin 11 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of IL11 mRNA
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL11 mRNA]
CTD PMID:15371230, PMID:15681167 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il12a interleukin 12A increases expression ISO deoxynivalenol results in increased expression of IL12A mRNA CTD PMID:9707511, PMID:27757495 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of IL12B mRNA
[Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein
CTD PMID:9194413, PMID:9707511, PMID:28935500 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il15 interleukin 15 increases expression ISO deoxynivalenol results in increased expression of IL15 mRNA CTD PMID:27757495 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
ISO [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL17A protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL17A protein] CTD PMID:28935500, PMID:32416088 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 decreases expression ISO deoxynivalenol results in decreased expression of IL18 mRNA CTD PMID:22968694 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18rap interleukin 18 receptor accessory protein decreases expression ISO deoxynivalenol results in decreased expression of IL18RAP mRNA CTD PMID:22968694 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of IL1A mRNA
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL1A mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]
CTD PMID:15371230, PMID:15681167, PMID:16009389 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
decreases expression
ISO deoxynivalenol results in increased expression of IL1B mRNA; deoxynivalenol results in increased expression of IL1B protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]
deoxynivalenol results in decreased expression of IL1B mRNA
CTD PMID:9194413, PMID:9707511, PMID:10344227, PMID:12604842, PMID:12773775, PMID:15371230, PMID:15681167, PMID:16009389, PMID:16364386, PMID:16687389, PMID:18308354, PMID:18433975, PMID:18614267, PMID:20702593, PMID:21873375, PMID:22454431, PMID:22968694, PMID:24793808, PMID:25392278, PMID:25549547, PMID:25766886, PMID:28935500, PMID:31034930 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1f10 interleukin 1 family member 10 increases expression ISO deoxynivalenol results in increased expression of IL1F10 mRNA CTD PMID:22968694 NCBI chr 3:1,408,560...1,416,601
Ensembl chr 3:1,413,671...1,416,599
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of IL1R1 mRNA
IL1R1 protein affects the susceptibility to [Lipopolysaccharides co-treated with deoxynivalenol]
CTD PMID:12773775, PMID:22968694 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO deoxynivalenol results in increased expression of IL1RL1 mRNA CTD PMID:26304032 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO deoxynivalenol results in increased expression of IL1RN mRNA CTD PMID:22968694 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 affects secretion
increases expression
increases stability
multiple interactions
affects expression
ISO deoxynivalenol affects the secretion of IL2 protein
deoxynivalenol results in increased expression of IL2 mRNA
deoxynivalenol results in increased stability of IL2 mRNA
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]
deoxynivalenol affects the expression of IL2 mRNA
CTD PMID:8560498, PMID:8658534, PMID:9194413, PMID:9439728, PMID:9707511, PMID:17166736 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 increases expression ISO deoxynivalenol results in increased expression of IL22RA2 mRNA CTD PMID:22968694 NCBI chr 1:15,084,136...15,107,423
Ensembl chr 1:15,093,599...15,106,954
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO deoxynivalenol results in increased expression of IL23A mRNA CTD PMID:22968694 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il33 interleukin 33 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of IL33 mRNA; deoxynivalenol results in increased expression of IL33 protein
Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 mRNA]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 protein]
CTD PMID:26304032 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
affects secretion
ISO deoxynivalenol results in increased expression of IL4 mRNA
deoxynivalenol results in increased expression of IL4 mRNA; deoxynivalenol results in increased expression of IL4 protein
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]
deoxynivalenol affects the secretion of IL4 protein
CTD PMID:8560498, PMID:8658534, PMID:9194413, PMID:9707511, PMID:22846391, PMID:24937323 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 affects secretion
increases expression
multiple interactions
ISO deoxynivalenol affects the secretion of IL5 protein
deoxynivalenol results in increased expression of IL5 mRNA
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]
CTD PMID:8560498, PMID:8658534 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
increases stability
increases expression
ISO deoxynivalenol results in decreased expression of IL6 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL6 protein; [Docosahexaenoic Acids co-treated with Eicosapentaenoic Acid] inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL6 protein; AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Fish Oils inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Indomethacin inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]
deoxynivalenol results in increased stability of IL6 mRNA
deoxynivalenol results in increased expression of IL6 mRNA; deoxynivalenol results in increased expression of IL6 protein
CTD PMID:9194413, PMID:9707511, PMID:10344227, PMID:11295263, PMID:11922776, PMID:12604842, PMID:12649040, PMID:14644621, PMID:14690764, PMID:15173396, PMID:15371230, PMID:15570035, PMID:15681167, PMID:16009389, PMID:16364386, PMID:16424113, PMID:16524712, PMID:16687389, PMID:17090620, PMID:18433975, PMID:18614267, PMID:19336499, PMID:19625342, PMID:20702593, PMID:21873375, PMID:22454431, PMID:22968694, PMID:24793808, PMID:24937323, PMID:27757495, PMID:28935500, PMID:31034930, PMID:32416088 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 decreases expression ISO deoxynivalenol results in decreased expression of IL7 mRNA CTD PMID:22968694 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D affects phosphorylation ISO deoxynivalenol affects the phosphorylation of INPP5D protein CTD PMID:23352502 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRAK1 protein] CTD PMID:26961612 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression ISO deoxynivalenol results in increased expression of IRF2BP2 mRNA CTD PMID:31863870 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Ist1 IST1 factor associated with ESCRT-III increases expression ISO deoxynivalenol results in increased expression of IST1 mRNA CTD PMID:31863870 NCBI chr19:41,968,692...41,990,843
Ensembl chr19:41,968,705...41,990,843
JBrowse link
G Itga10 integrin subunit alpha 10 decreases expression ISO deoxynivalenol results in decreased expression of ITGA10 mRNA CTD PMID:31863870 NCBI chr 2:198,772,937...198,792,253
Ensembl chr 2:198,772,937...198,792,253
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO deoxynivalenol results in increased expression of ITGB2 mRNA CTD PMID:22968694 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itgbl1 integrin subunit beta like 1 decreases expression ISO deoxynivalenol results in decreased expression of ITGBL1 mRNA CTD PMID:31863870 NCBI chr15:110,114,148...110,378,970
Ensembl chr15:110,114,148...110,378,969
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO deoxynivalenol results in increased expression of JAK1 mRNA CTD PMID:22454431 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak2 Janus kinase 2 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of JAK2 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]
CTD PMID:22454431 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
increases activity
increases expression
affects localization
affects activity
ISO deoxynivalenol results in increased expression of and results in increased phosphorylation of JUN protein
deoxynivalenol results in increased phosphorylation of JUN protein
deoxynivalenol results in increased activity of JUN protein
deoxynivalenol results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of JUN protein
deoxynivalenol affects the localization of JUN protein
deoxynivalenol affects the activity of JUN protein
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUN protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of JUN protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]
CTD PMID:10662601, PMID:12604842, PMID:15371230, PMID:15681167, PMID:15772366, PMID:16424113, PMID:19360757, PMID:23352502, PMID:23792671, PMID:24937323, PMID:32416088 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
increases activity
affects activity
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUNB protein]
deoxynivalenol results in increased expression of JUNB mRNA
deoxynivalenol affects the activity of JUNB protein
CTD PMID:10662601, PMID:15371230, PMID:15681167, PMID:15772366 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit affects activity
affects localization
increases activity
increases expression
multiple interactions
ISO deoxynivalenol affects the activity of JUND protein
deoxynivalenol affects the localization of JUND protein
deoxynivalenol results in increased activity of JUND protein
deoxynivalenol results in increased expression of JUND mRNA
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUND protein]
CTD PMID:10662601, PMID:12604842, PMID:15772366, PMID:22846391 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kat2a lysine acetyltransferase 2A multiple interactions ISO KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form] CTD PMID:30286430 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kat2b lysine acetyltransferase 2B increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of KAT2B protein
KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]
CTD PMID:30286430 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of KBTBD11 protein CTD PMID:23811945 NCBI chr16:79,696,395...79,716,129
Ensembl chr16:79,696,891...79,700,992
JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 decreases expression ISO deoxynivalenol results in decreased expression of KCNMB4 mRNA CTD PMID:26763390 NCBI chr 7:59,461,808...59,514,759
Ensembl chr 7:59,461,799...59,514,939
JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 decreases expression ISO deoxynivalenol results in decreased expression of KDELR3 mRNA CTD PMID:31863870 NCBI chr 7:120,749,680...120,760,163
Ensembl chr 7:120,749,752...120,760,160
JBrowse link
G Kdm4b lysine demethylase 4B affects phosphorylation ISO deoxynivalenol affects the phosphorylation of KDM4B protein CTD PMID:23811945 NCBI chr 9:10,656,035...10,734,127
Ensembl chr 9:10,653,216...10,734,073
JBrowse link
G Khdc4 KH domain containing 4, pre-mRNA splicing factor increases expression ISO deoxynivalenol results in increased expression of KHDC4 mRNA CTD PMID:31863870 NCBI chr 2:188,051,657...188,080,280
Ensembl chr 2:188,052,236...188,080,301
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO deoxynivalenol results in increased expression of KHDRBS3 mRNA CTD PMID:31863870 NCBI chr 7:110,031,819...110,179,475
Ensembl chr 7:110,031,696...110,179,468
JBrowse link
G Kif11 kinesin family member 11 increases expression ISO deoxynivalenol results in increased expression of KIF11 mRNA CTD PMID:31863870 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif2c kinesin family member 2C increases expression ISO deoxynivalenol results in increased expression of KIF2C mRNA CTD PMID:31863870 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Kitlg KIT ligand increases expression ISO deoxynivalenol results in increased expression of KITLG mRNA CTD PMID:27757495, PMID:31863870 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klhl30 kelch-like family member 30 decreases expression ISO deoxynivalenol results in decreased expression of KLHL30 mRNA CTD PMID:26763390 NCBI chr 9:98,490,583...98,500,880
Ensembl chr 9:98,490,608...98,500,867
JBrowse link
G Kmt2a lysine methyltransferase 2A multiple interactions
increases expression
ISO AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]; deoxynivalenol promotes the reaction [SP1 protein binds to KMT2A promoter]; SP1 protein promotes the reaction [deoxynivalenol results in increased expression of KMT2A mRNA] CTD PMID:19438726 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO deoxynivalenol results in decreased expression of LAMB1 mRNA CTD PMID:31863870 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of LARP7 protein CTD PMID:23352502 NCBI chr 2:231,866,888...231,882,002
Ensembl chr 2:231,867,135...231,881,939
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases phosphorylation
affects phosphorylation
ISO deoxynivalenol results in increased phosphorylation of LCP1 protein
deoxynivalenol affects the phosphorylation of LCP1 protein
CTD PMID:23352502, PMID:23811945 NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO [Colforsin co-treated with deoxynivalenol] results in increased expression of LHCGR mRNA CTD PMID:26783879 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Lig1 DNA ligase 1 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of LIG1 protein CTD PMID:23811945 NCBI chr 1:75,356,212...75,394,757
Ensembl chr 1:75,356,220...75,394,758
JBrowse link
G Lmna lamin A/C affects phosphorylation
decreases phosphorylation
ISO deoxynivalenol affects the phosphorylation of LMNA protein
deoxynivalenol results in decreased phosphorylation of LMNA protein
CTD PMID:23352502, PMID:23811945 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lmnb1 lamin B1 increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of LMNB1 protein CTD PMID:23811945 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Lmo2 LIM domain only 2 decreases expression ISO deoxynivalenol results in decreased expression of LMO2 mRNA CTD PMID:26763390 NCBI chr 3:93,909,156...93,931,888
Ensembl chr 3:93,909,156...93,931,871
JBrowse link
G LOC103694381 lymphotoxin-beta decreases expression ISO deoxynivalenol results in decreased expression of LTB mRNA CTD PMID:22968694 NCBI chr20:4,861,343...4,863,513
Ensembl chr20:4,861,335...4,863,198
JBrowse link
G LOC691272 similar to reproductive homeobox on X chromosome, 11 decreases expression ISO deoxynivalenol results in decreased expression of SHOX mRNA CTD PMID:26763390 NCBI chr  X:124,045,727...124,052,708
Ensembl chr  X:124,045,737...124,052,632
JBrowse link
G LOC691918 similar to Centrosomal protein of 27 kDa (Cep27 protein) increases expression ISO deoxynivalenol results in increased expression of HAUS2 mRNA CTD PMID:31863870 NCBI chr 3:112,371,709...112,377,939
Ensembl chr 3:112,385,601...112,396,032
Ensembl chr 3:112,385,601...112,396,032
JBrowse link
G Loxl3 lysyl oxidase-like 3 decreases expression ISO deoxynivalenol results in decreased expression of LOXL3 mRNA CTD PMID:31863870 NCBI chr 4:113,866,782...113,883,713
Ensembl chr 4:113,866,804...113,883,477
JBrowse link
G Lpxn leupaxin decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of LPXN protein CTD PMID:23352502 NCBI chr 1:229,642,437...229,674,129
Ensembl chr 1:229,642,412...229,674,134
JBrowse link
G Lsp1 lymphocyte-specific protein 1 affects phosphorylation
decreases expression
increases phosphorylation
ISO deoxynivalenol affects the phosphorylation of LSP1 protein
deoxynivalenol results in decreased expression of LSP1 mRNA
deoxynivalenol results in increased phosphorylation of LSP1 protein
CTD PMID:23352502, PMID:23811945, PMID:31863870 NCBI chr 1:215,628,750...215,662,505
Ensembl chr 1:215,628,785...215,662,504
JBrowse link
G Lta lymphotoxin alpha increases expression ISO deoxynivalenol results in increased expression of LTA mRNA CTD PMID:22968694 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 decreases expression ISO deoxynivalenol results in decreased expression of LTBP2 mRNA CTD PMID:31863870 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO deoxynivalenol results in increased expression of MAFF mRNA CTD PMID:24247028 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mall mal, T-cell differentiation protein-like decreases expression ISO deoxynivalenol results in decreased expression of MALL mRNA CTD PMID:31863870 NCBI chr 3:120,272,583...120,307,090
Ensembl chr 3:120,272,583...120,306,551
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases phosphorylation
multiple interactions
ISO deoxynivalenol results in increased phosphorylation of MAP2K4 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K4 protein]
CTD PMID:32416088 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions
increases phosphorylation
ISO AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K6 protein] CTD PMID:20181660 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
increases phosphorylation
ISO AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP3K5 protein] CTD PMID:20181660 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map4 microtubule-associated protein 4 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of MAP4 protein CTD PMID:23811945 NCBI chr 8:118,013,584...118,159,934
Ensembl chr 8:118,013,612...118,159,933
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]
[deoxynivalenol results in increased phosphorylation of MAPK1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
CTD PMID:12377986, PMID:12604842, PMID:14644621, PMID:14690764, PMID:15570035, PMID:15772366, PMID:15976193, PMID:16009389, PMID:16424113, PMID:17707346, PMID:18006205, PMID:18485432, PMID:18502741, PMID:19360757, PMID:20633634, PMID:23352502, PMID:23811945, PMID:24937323, PMID:32416088 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 decreases expression ISO deoxynivalenol results in decreased expression of MAPK12 mRNA CTD PMID:31863870 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases expression
increases phosphorylation
ISO deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK14 protein
deoxynivalenol results in increased expression of MAPK14 mRNA
deoxynivalenol results in increased phosphorylation of MAPK14 protein
CTD PMID:15976193, PMID:16364386, PMID:20702593 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [deoxynivalenol results in increased phosphorylation of MAPK3 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:12377986, PMID:12604842, PMID:14644621, PMID:14690764, PMID:15570035, PMID:15772366, PMID:15976193, PMID:16009389, PMID:16424113, PMID:17707346, PMID:18006205, PMID:18485432, PMID:18502741, PMID:19360757, PMID:20633634, PMID:23352502, PMID:23811945, PMID:24937323, PMID:32416088 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases activity
increases phosphorylation
multiple interactions
ISO deoxynivalenol results in decreased activity of MAPK8 protein
deoxynivalenol results in increased phosphorylation of MAPK8 protein
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]
[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD PMID:12377986, PMID:12604842, PMID:14644621, PMID:14690764, PMID:15570035, PMID:15772366, PMID:16424113, PMID:18485432, PMID:18502741, PMID:19360757, PMID:20708668, PMID:23352502, PMID:32416088 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases activity
increases phosphorylation
decreases phosphorylation
decreases expression
multiple interactions
ISO deoxynivalenol results in decreased activity of MAPK9 protein
deoxynivalenol results in increased phosphorylation of MAPK9 protein
deoxynivalenol results in decreased phosphorylation of MAPK9 protein
deoxynivalenol results in decreased expression of MAPK9 mRNA
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]
[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK9 protein
CTD PMID:12377986, PMID:12604842, PMID:14644621, PMID:14690764, PMID:15371230, PMID:15570035, PMID:15772366, PMID:16424113, PMID:18485432, PMID:18502741, PMID:19360757, PMID:20633634, PMID:20708668, PMID:23352502, PMID:23811945 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of MARCKS protein CTD PMID:23811945 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO deoxynivalenol results in increased expression of MDM2 mRNA CTD PMID:31863870 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mdm4 MDM4 regulator of p53 increases expression ISO deoxynivalenol results in increased expression of MDM4 mRNA CTD PMID:22846391 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720
JBrowse link
G Meis3 Meis homeobox 3 decreases response to substance
decreases expression
ISO MEIS3 protein results in decreased susceptibility to deoxynivalenol
deoxynivalenol results in decreased expression of MEIS3 mRNA
CTD PMID:26763390 NCBI chr 1:78,065,617...78,079,698
Ensembl chr 1:78,068,931...78,079,862
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase affects phosphorylation ISO deoxynivalenol affects the phosphorylation of MET protein CTD PMID:23811945 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mettl14 methyltransferase like 14 increases expression ISO deoxynivalenol results in increased expression of METTL14 mRNA CTD PMID:31863870 NCBI chr 2:227,566,811...227,583,047
Ensembl chr 2:227,566,815...227,582,895
JBrowse link
G Mki67 marker of proliferation Ki-67 increases phosphorylation
multiple interactions
increases expression
ISO deoxynivalenol results in increased phosphorylation of MKI67 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of MKI67 protein]
deoxynivalenol results in increased expression of MKI67 mRNA
CTD PMID:23352502, PMID:23811945, PMID:31863870, PMID:32416088 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 affects phosphorylation
decreases expression
ISO deoxynivalenol affects the phosphorylation of MKNK2 protein
deoxynivalenol results in decreased expression of MKNK2 mRNA
CTD PMID:23811945, PMID:31863870 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Mpo myeloperoxidase increases activity ISO deoxynivalenol results in increased activity of MPO protein CTD PMID:24937323 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 decreases expression ISO deoxynivalenol results in decreased expression of MRAP2 mRNA CTD PMID:31863870 NCBI chr 8:94,801,336...94,858,192
Ensembl chr 8:94,801,336...94,857,443
JBrowse link
G Mrpl39 mitochondrial ribosomal protein L39 increases expression ISO deoxynivalenol results in increased expression of MRPL39 mRNA CTD PMID:31863870 NCBI chr11:24,181,605...24,200,022
Ensembl chr11:24,181,658...24,199,968
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B increases expression ISO deoxynivalenol results in increased expression of MRPS18B mRNA CTD PMID:31863870 NCBI chr20:3,344,870...3,350,929
Ensembl chr20:3,344,870...3,350,927
JBrowse link
G Mrps22 mitochondrial ribosomal protein S22 increases expression ISO deoxynivalenol results in increased expression of MRPS22 mRNA CTD PMID:31863870 NCBI chr 8:106,604,421...106,617,591
Ensembl chr 8:106,604,379...106,617,597
JBrowse link
G Mrps30 mitochondrial ribosomal protein S30 increases expression ISO deoxynivalenol results in increased expression of MRPS30 mRNA CTD PMID:24247028, PMID:31863870 NCBI chr 2:51,042,548...51,049,423
Ensembl chr 2:51,042,546...51,049,449
JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 increases expression ISO deoxynivalenol results in increased expression of MRPS31 mRNA CTD PMID:31863870 NCBI chr16:74,467,874...74,504,834
Ensembl chr16:74,467,851...74,496,731
JBrowse link
G Msx2 msh homeobox 2 increases expression ISO deoxynivalenol results in increased expression of MSX2 mRNA CTD PMID:31863870 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Mta3 metastasis associated 1 family, member 3 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of MTA3 protein CTD PMID:23352502 NCBI chr 6:6,904,449...7,036,929
Ensembl chr 6:6,908,684...7,031,828
JBrowse link
G Mtdh metadherin affects phosphorylation ISO deoxynivalenol affects the phosphorylation of LYRIC protein CTD PMID:23352502 NCBI chr 7:72,771,018...72,830,599
Ensembl chr 7:72,772,440...72,827,908
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO deoxynivalenol results in decreased expression of MTHFD2 mRNA CTD PMID:31863870 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mtrex Mtr4 exosome RNA helicase increases expression ISO deoxynivalenol results in increased expression of MTREX mRNA CTD PMID:31863870 NCBI chr 2:44,726,716...44,787,013
Ensembl chr 2:44,717,781...44,786,963
JBrowse link
G Muc16 mucin 16, cell surface associated affects phosphorylation ISO deoxynivalenol affects the phosphorylation of MUC16 protein CTD PMID:23811945 NCBI chr 8:18,438,838...18,639,777 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of MUC5AC mRNA
deoxynivalenol results in increased expression of and results in increased secretion of MUC5AC protein
CTD PMID:24496642 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of MUC5B mRNA
deoxynivalenol results in increased expression of and results in increased secretion of MUC5B protein
CTD PMID:24496642 NCBI chr 1:214,778,459...214,811,237
Ensembl chr 1:214,778,496...214,810,720
JBrowse link
G Mybbp1a MYB binding protein 1a decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of MYBBP1A protein CTD PMID:23352502 NCBI chr10:59,000,400...59,010,794
Ensembl chr10:59,000,397...59,010,903
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO deoxynivalenol results in increased expression of MYC mRNA CTD PMID:24247028 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor affects phosphorylation ISO deoxynivalenol affects the phosphorylation of MYCN protein CTD PMID:23352502 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MYD88 protein] CTD PMID:26961612 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myh11 myosin heavy chain 11 decreases phosphorylation ISO deoxynivalenol results in decreased phosphorylation of MYH11 protein CTD PMID:23811945 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
JBrowse link
G Myh9 myosin, heavy chain 9 affects phosphorylation
increases phosphorylation
ISO deoxynivalenol affects the phosphorylation of MYH9 protein
deoxynivalenol results in increased phosphorylation of MYH9 protein
CTD PMID:23352502, PMID:23811945 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G Myo5c myosin VC decreases expression ISO deoxynivalenol results in decreased expression of MYO5C mRNA CTD PMID:26763390 NCBI chr 8:82,171,296...82,248,109
Ensembl chr 8:82,171,497...82,247,544
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase decreases expression ISO deoxynivalenol results in decreased expression of NAGLU mRNA CTD PMID:31863870 NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO deoxynivalenol results in increased expression of NAMPT mRNA CTD PMID:31863870 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 decreases expression ISO deoxynivalenol results in decreased expression of NANOS1 mRNA CTD PMID:31863870 NCBI chr 1:282,134,676...282,140,370
Ensembl chr 1:282,134,981...282,135,772
JBrowse link
G Ncl nucleolin affects phosphorylation ISO deoxynivalenol affects the phosphorylation of NCL protein CTD PMID:23352502 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Ndc80 NDC80 kinetochore complex component increases expression ISO deoxynivalenol results in increased expression of NDC80 mRNA CTD PMID:31863870 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase increases expression ISO deoxynivalenol results in increased expression of NEDD4L mRNA CTD PMID:31863870 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 affects localization ISO deoxynivalenol affects the localization of NFATC1 protein CTD PMID:21074547, PMID:22846391 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO deoxynivalenol analog results in increased activity of NFE2L2 protein; deoxynivalenol results in increased activity of NFE2L2 protein CTD PMID:30244016 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases activity
affects localization
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of NFKB1 protein]; deoxynivalenol results in decreased activity of [NFKB1 protein binds to NFKB1 protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein]
deoxynivalenol affects the localization of NFKB1 protein
CTD PMID:8887449, PMID:12604842, PMID:15772366 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression
multiple interactions
ISO deoxynivalenol results in increased expression of NFKB2 mRNA
deoxynivalenol inhibits the reaction [NFKB2 protein binds to CXCL8 promoter]
CTD PMID:17636245, PMID:22846391 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation
multiple interactions
increases phosphorylation
increases expression
decreases expression
ISO deoxynivalenol results in increased degradation of NFKBIA protein
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein]
deoxynivalenol results in increased phosphorylation of NFKBIA protein
deoxynivalenol results in increased expression of NFKBIA mRNA
deoxynivalenol results in decreased expression of NFKBIA mRNA; deoxynivalenol results in decreased expression of NFKBIA protein
lipopolysaccharide, E coli O55-B5 inhibits the reaction [deoxynivalenol results in increased degradation of NFKBIA protein]
CTD PMID:8887449, PMID:18485432, PMID:23253260, PMID:24937323, PMID:26961612 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta increases expression ISO deoxynivalenol results in increased expression of NFKBIB mRNA CTD PMID:22846391 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Niban3 niban apoptosis regulator 3 affects phosphorylation ISO deoxynivalenol affects the phosphorylation of NIBAN3 protein CTD PMID:23811945 NCBI chr16:20,027,100...20,038,720
Ensembl chr16:20,027,348...20,038,716
JBrowse link
G Nipbl NIPBL, cohesin loading factor increases phosphorylation ISO deoxynivalenol results in increased phosphorylation of NIPBL protein CTD PMID:23811945 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions ISO [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA] CTD PMID:22003189 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 increases expression ISO deoxynivalenol results in increased expression of NOLC1 mRNA CTD PMID:24247028 NCBI chr 1:265,829,055...265,839,819
Ensembl chr 1:265,829,108...265,839,818
JBrowse link
G Nop56 NOP56 ribonucleoprotein affects phosphorylation
increases phosphorylation
ISO deoxynivalenol affects the phosphorylation of NOP56 protein
deoxynivalenol results in increased phosphorylation of NOP56 protein
CTD PMID:23352502, PMID:23811945 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]
deoxynivalenol results in increased expression of NOS2 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein