Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxybenzoate
go back to main search page
Accession:CHEBI:24675 term browser browse the term
Definition:Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent.
Synonyms:related_synonym: hydroxybenzoates
 cyclic_relationship: is_conjugate_base_of CHEBI:24676


show annotations for term's descendants           Sort by:
 
3,4-dihydroxybenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 increases expression
multiple interactions
ISO 3,4-dihydroxybenzoate results in increased expression of EPAS1 mRNA
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EPAS1 mRNA
CTD PMID:19679656 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
affects localization
multiple interactions
ISO
EXP
3,4-dihydroxybenzoate results in increased expression of HIF1A mRNA
3,4-dihydroxybenzoate affects the localization of HIF1A protein
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A mRNA
CTD PMID:19679656 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HMOX1 mRNA; [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HMOX1 protein
3,4-dihydroxybenzoate results in increased expression of HMOX1 mRNA; 3,4-dihydroxybenzoate results in increased expression of HMOX1 protein
CTD PMID:19679656 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO 3,4-dihydroxybenzoate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC40A1 protein] CTD PMID:19679656 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of SOD2 protein
3,4-dihydroxybenzoate results in increased expression of SOD2 protein
CTD PMID:19679656 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
physostigmine salicylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO physostigmine salicylate results in decreased activity of ACHE protein CTD PMID:623676 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    chemical entity 19786
      molecular entity 19784
        ion 15941
          anion 14967
            organic anion 3037
              carboxylic acid anion 2396
                monocarboxylic acid anion 1501
                  benzoates 1271
                    hydroxybenzoate 6
                      2-hydroxy-7,8-dihydropteroate 0
                      3-geranyl-4-hydroxybenzoate(1-) 0
                      3-hydroxy-4-methylanthranilate 0
                      3-hydroxyanthranilate 0
                      3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate + 0
                      4-aminosalicylate(1-) 0
                      5-chlorosalicylate 0
                      6-methylsalicylate 0
                      N-benzoyl-4-hydroxyanthranilate 0
                      avenanthramide B(1-) 0
                      avenanthramide C(1-) 0
                      chromoxane cyanin R(3-) + 0
                      dihydroxybenzoate + 5
                      mesalaminate(1-) 0
                      monohydroxybenzoate + 1
                      syringate + 0
                      trihydroxybenzoate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19596
                        carbon atom 19586
                          organic molecular entity 19586
                            organic ion 8465
                              organic anion 3037
                                carboxylic acid anion 2396
                                  monocarboxylic acid anion 1501
                                    benzoates 1271
                                      hydroxybenzoate 6
                                        2-hydroxy-7,8-dihydropteroate 0
                                        3-geranyl-4-hydroxybenzoate(1-) 0
                                        3-hydroxy-4-methylanthranilate 0
                                        3-hydroxyanthranilate 0
                                        3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate + 0
                                        4-aminosalicylate(1-) 0
                                        5-chlorosalicylate 0
                                        6-methylsalicylate 0
                                        N-benzoyl-4-hydroxyanthranilate 0
                                        avenanthramide B(1-) 0
                                        avenanthramide C(1-) 0
                                        chromoxane cyanin R(3-) + 0
                                        dihydroxybenzoate + 5
                                        mesalaminate(1-) 0
                                        monohydroxybenzoate + 1
                                        syringate + 0
                                        trihydroxybenzoate + 0
paths to the root