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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxybenzoate
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Accession:CHEBI:24675 term browser browse the term
Definition:Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent.
Synonyms:related_synonym: hydroxybenzoates
 cyclic_relationship: is_conjugate_base_of CHEBI:24676



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3,4-dihydroxybenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 increases expression
multiple interactions
ISO 3,4-dihydroxybenzoate results in increased expression of EPAS1 mRNA
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EPAS1 mRNA
CTD PMID:19679656 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
affects localization
ISO
EXP
3,4-dihydroxybenzoate results in increased expression of HIF1A mRNA
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A mRNA
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein
3,4-dihydroxybenzoate affects the localization of HIF1A protein
CTD PMID:19679656 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HMOX1 mRNA; [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HMOX1 protein
3,4-dihydroxybenzoate results in increased expression of HMOX1 mRNA; 3,4-dihydroxybenzoate results in increased expression of HMOX1 protein
CTD PMID:19679656 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO 3,4-dihydroxybenzoate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC40A1 protein] CTD PMID:19679656 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of SOD2 protein
3,4-dihydroxybenzoate results in increased expression of SOD2 protein
CTD PMID:19679656 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
physostigmine salicylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO physostigmine salicylate results in decreased activity of ACHE protein CTD PMID:623676 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      molecular entity 19916
        ion 16729
          organic ion 9870
            organic anion 3614
              carboxylic acid anion 2480
                monocarboxylic acid anion 1592
                  benzoates 1276
                    hydroxybenzoate 6
                      2-hydroxy-7,8-dihydropteroate 0
                      3-geranyl-4-hydroxybenzoate(1-) 0
                      3-hydroxy-4-methylanthranilate 0
                      3-hydroxyanthranilate 0
                      3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate + 0
                      4-aminosalicylate(1-) 0
                      5-chlorosalicylate 0
                      6-methylsalicylate 0
                      N-benzoyl-4-hydroxyanthranilate 0
                      avenanthramide B(1-) 0
                      avenanthramide C(1-) 0
                      chromoxane cyanin R(3-) + 0
                      dihydroxybenzoate + 5
                      mesalaminate(1-) 0
                      monohydroxybenzoate + 1
                      syringate + 0
                      trihydroxybenzoate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic ion 9870
                              organic anion 3614
                                carboxylic acid anion 2480
                                  monocarboxylic acid anion 1592
                                    benzoates 1276
                                      hydroxybenzoate 6
                                        2-hydroxy-7,8-dihydropteroate 0
                                        3-geranyl-4-hydroxybenzoate(1-) 0
                                        3-hydroxy-4-methylanthranilate 0
                                        3-hydroxyanthranilate 0
                                        3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate + 0
                                        4-aminosalicylate(1-) 0
                                        5-chlorosalicylate 0
                                        6-methylsalicylate 0
                                        N-benzoyl-4-hydroxyanthranilate 0
                                        avenanthramide B(1-) 0
                                        avenanthramide C(1-) 0
                                        chromoxane cyanin R(3-) + 0
                                        dihydroxybenzoate + 5
                                        mesalaminate(1-) 0
                                        monohydroxybenzoate + 1
                                        syringate + 0
                                        trihydroxybenzoate + 0
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