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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroquinones
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Accession:CHEBI:24646 term browser browse the term
Definition:Benzenediols that have the hydroxy substituents in the 1- and 4-positions.
Synonyms:related_synonym: 1,4-benzoquinols;   Formula=C6H2O2R4;   SMILES=OC1=C(*)C(*)=C(O)C(*)=C1*;   a 1,4-benzoquinol;   a quinol;   benzene-1,4-diols
 alt_id: CHEBI:134188;   MESH:D006873
 xref_mesh: MESH:D006873


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hydroquinones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases response to substance ISO NFE2L2 protein results in decreased susceptibility to Hydroquinones CTD PMID:20932822 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
1,4-dihydroxy-2-naphthoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:27837168 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of GPR35 protein CTD PMID:20826425 NCBI chr 9:100,129,428...100,141,269
Ensembl chr 9:100,137,881...100,138,801
JBrowse link
2,5-di-tert-butylbenzene-1,4-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 2,5-di-tert-butylhydroquinone results in increased expression of GSTP1 protein CTD PMID:12680784 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases response to substance ISO NFE2L2 gene mutant form results in increased susceptibility to 2,5-di-tert-butylhydroquinone CTD PMID:12842875 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
2-tert-butylhydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of ABCC1 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCC1 protein CTD PMID:11836020 PMID:16014739 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO
EXP
2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCC2 protein CTD PMID:11264000 PMID:11836020 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of ABCG2 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCG2 protein
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]
CTD PMID:17077187 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO 2-tert-butylhydroquinone results in increased expression of ADH7 mRNA CTD PMID:16014739 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO
EXP
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]; AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]
2-tert-butylhydroquinone results in increased activity of and results in increased localization of AHR protein
CTD PMID:12948865 PMID:15608132 PMID:17077187 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 2-tert-butylhydroquinone results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein] CTD PMID:23112101 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ar androgen receptor multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of ATP5F1A protein] CTD PMID:31726083 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Bach1 BTB domain and CNC homolog 1 affects localization
multiple interactions
ISO 2-tert-butylhydroquinone affects the localization of BACH1 protein
2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; [ferric chloride results in increased oxidation of 2-tert-butylhydroquinone] promotes the reaction [2-tert-butylhydroquinone analog binds to BACH1 protein]
CTD PMID:28645578 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in decreased expression of BAX protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of BAX mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of BAX protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
[2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in decreased expression of BAX protein
CTD PMID:22275372 PMID:26878773 PMID:28583816 PMID:32565124 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to BCL2 promoter]; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in increased expression of BCL2 protein; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of BCL2 mRNA]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of BCL2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in decreased expression of BCL2 protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
2-tert-butylhydroquinone results in increased expression of BCL2 mRNA; 2-tert-butylhydroquinone results in increased expression of BCL2 protein
CTD PMID:22275372 PMID:26878773 PMID:28583816 PMID:32565124 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bco2 beta-carotene oxygenase 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of BCO2 mRNA CTD PMID:16014739 NCBI chr 8:54,965,577...54,990,604
Ensembl chr 8:54,965,583...54,998,864
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 2-tert-butylhydroquinone results in increased expression of BLVRB mRNA CTD PMID:16014739 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of CASP3 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased cleavage of CASP3 protein]
2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]
CTD PMID:22275372 PMID:25341683 PMID:25645596 PMID:26878773 PMID:28583816 PMID:32073640 PMID:32428544 PMID:32565124 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP4 protein] CTD PMID:25341683 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein] CTD PMID:22275372 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Cat catalase multiple interactions
increases activity
ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
2-tert-butylhydroquinone results in increased activity of CAT protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CAT mRNA]
CTD PMID:26878773 PMID:32428544 PMID:32565124 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CBR3 mRNA CTD PMID:16014739 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion ISO 2-tert-butylhydroquinone results in increased secretion of CCL5 protein CTD PMID:30806763 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of CCN2 mRNA CTD PMID:16014739 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of CCND1 protein
2-tert-butylhydroquinone promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]
CTD PMID:26878773 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd5l Cd5 molecule-like increases expression ISO 2-tert-butylhydroquinone results in increased expression of CD5L mRNA CTD PMID:16014739 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein] CTD PMID:30171972 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd86 CD86 molecule increases expression ISO 2-tert-butylhydroquinone results in increased expression of CD86 protein CTD PMID:19033392 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein]
2-tert-butylhydroquinone results in increased expression of CDK4 protein
CTD PMID:26878773 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression
ISO 2-tert-butylhydroquinone results in increased expression of and results in increased activity of CES1 protein alternative form; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form] CTD PMID:19715681 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; 2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]] CTD PMID:21443188 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 affects response to substance ISO CREG2 gene SNP affects the susceptibility to 2-tert-butylhydroquinone CTD PMID:25622337 NCBI chr 9:46,328,088...46,402,237
Ensembl chr 9:46,360,061...46,401,911
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein]; 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein]; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CSF1R protein CTD PMID:23112101 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Ctsk cathepsin K multiple interactions ISO [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein CTD PMID:23112101 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cul3 cullin 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein] CTD PMID:18417180 PMID:30261176 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL1 mRNA CTD PMID:30806763 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL1 mRNA CTD PMID:30806763 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5a cytochrome b5 type A increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYB5A mRNA CTD PMID:16014739 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of CYBB protein] CTD PMID:28844481 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CYP11A1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CYP11A1 protein] CTD PMID:32565124 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO 2-tert-butylhydroquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; 2-tert-butylhydroquinone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-tert-butylhydroquinone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; FH535 inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased activity of CYP1A1 protein]; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP1A1 mRNA]
2-tert-butylhydroquinone results in increased expression of and results in increased activity of CYP1A1 protein; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased activity of CYP1A1 protein]
CTD PMID:9973208 PMID:15608132 PMID:15627257 PMID:16581943 PMID:25174530 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYP2A5 mRNA CTD PMID:29788535 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYP2C19 mRNA; 2-tert-butylhydroquinone results in increased expression of CYP2C19 protein CTD PMID:24830941 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein] CTD PMID:25341683 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dsc3 desmocollin 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of DSC3 mRNA CTD PMID:16014739 NCBI chr18:11,753,047...11,789,846
Ensembl chr18:11,753,047...11,789,708
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions
EXP
ISO
2-tert-butylhydroquinone results in increased expression of EPHX1 mRNA
NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon]
2-tert-butylhydroquinone results in increased expression of EPHX1 exon; 2-tert-butylhydroquinone results in increased expression of EPHX1 protein alternative form
CTD PMID:20650352 PMID:24704207 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Esd esterase D increases expression ISO 2-tert-butylhydroquinone results in increased expression of ESD mRNA CTD PMID:16014739 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions EXP 2-tert-butylhydroquinone promotes the reaction [FGF1 protein results in increased abundance of and results in increased secretion of Glutathione]; FGF1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein] CTD PMID:16524372 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf18 fibroblast growth factor 18 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of FGF18 mRNA CTD PMID:16014739 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased expression of FOS protein
2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of FOS protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FOS protein]; 2-tert-butylhydroquinone promotes the reaction [FOS protein binds to CYP2C9 promoter]
CTD PMID:24830941 PMID:28844481 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of FSHB protein] CTD PMID:32565124 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA]; PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA]; wortmannin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] CTD PMID:23829535 PMID:25003661 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of FTL1 mRNA CTD PMID:16014739 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Ftmt ferritin mitochondrial increases expression ISO 2-tert-butylhydroquinone results in increased expression of FTMT mRNA CTD PMID:15664434 NCBI chr18:47,294,292...47,295,541
Ensembl chr18:47,294,292...47,295,541
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha affects localization ISO 2-tert-butylhydroquinone affects the localization of GABPA protein CTD PMID:16308312 NCBI chr11:24,293,845...24,322,822
Ensembl chr11:24,263,281...24,322,815
JBrowse link
G Gata3 GATA binding protein 3 increases activity ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein CTD PMID:22250088 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression
increases expression
multiple interactions
increases activity
ISO
EXP
2-tert-butylhydroquinone affects the expression of GCLC mRNA
2-tert-butylhydroquinone results in increased expression of GCLC mRNA
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of GCLC mRNA]; [2-tert-butylhydroquinone results in increased activity of GCLC protein] which results in increased abundance of Glutathione; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]
CTD PMID:7955076 PMID:10978506 PMID:12007577 PMID:15946948 PMID:16014739 PMID:17980396 PMID:19183254 PMID:19328227 PMID:22250088 PMID:23906629 PMID:24128855 PMID:27178040 PMID:30547568 PMID:30806763 PMID:32428544 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression
ISO
EXP
NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA]
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; [2,2',4,4'-tetrabromodiphenyl ether co-treated with 2-tert-butylhydroquinone] results in increased expression of GCLM mRNA
CTD PMID:10978506 PMID:12007577 PMID:12081989 PMID:16014739 PMID:19183254 PMID:19328227 PMID:24632381 PMID:25003661 PMID:25305463 PMID:30547568 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO 2-tert-butylhydroquinone results in increased expression of GPR87 mRNA CTD PMID:16014739 NCBI chr 2:149,398,949...149,418,041
Ensembl chr 2:149,398,949...149,417,212
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
EXP 2-tert-butylhydroquinone results in increased expression of GPX1 protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of GPX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of GPX1 protein]
CTD PMID:28583816 PMID:32565124 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of GRIA1 mRNA CTD PMID:16014739 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased activity of GSR protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD PMID:12572858 PMID:24970285 PMID:32565124 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased expression of GSS mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSS mRNA
CTD PMID:10978506 PMID:19183254 PMID:32428544 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
increases activity
multiple interactions
EXP
ISO
2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA; 2-tert-butylhydroquinone results in increased expression of GSTA2 protein
2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA
2-tert-butylhydroquinone results in increased activity of GSTA1 protein
Tetradecanoylphorbol Acetate promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2]; 2-tert-butylhydroquinone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of GSTA2 protein; [S-Nitroso-N-Acetylpenicillamine co-treated with 2-tert-butylhydroquinone] results in increased expression of GSTA2; Dexamethasone promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of GSTA2 protein]; Dexamethasone promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA]; N-acetylsphingosine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 protein]
CTD PMID:7568053 PMID:7587946 PMID:12242683 PMID:15155840 PMID:15319326 PMID:15357004 PMID:15627257 PMID:15870285 PMID:16014739 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP 2-tert-butylhydroquinone results in increased expression of GSTA5 mRNA CTD PMID:20650352 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases activity
increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased activity of GSTA1 protein
2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA
Tetradecanoylphorbol Acetate promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA]
CTD PMID:7568053 PMID:15627257 PMID:16014739 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of GSTM1 protein
2-tert-butylhydroquinone results in increased expression of GSTM1 mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSTM1 mRNA
CTD PMID:21443188 PMID:32428544 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP
ISO
2-tert-butylhydroquinone results in increased expression of GSTP1 protein
2-tert-butylhydroquinone results in increased expression of GSTP1 mRNA
CTD PMID:12680784 PMID:15533597 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gzmb granzyme B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein] CTD PMID:30171972 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G H2ax H2A.X variant histone multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of H2AX protein] CTD PMID:28583816 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hbg1 hemoglobin subunit gamma 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of HBG1 mRNA CTD PMID:21464371 NCBI chr 1:168,992,841...168,994,219
Ensembl chr 1:168,992,722...168,994,253
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression EXP 2-tert-butylhydroquinone results in decreased expression of HES1 protein CTD PMID:29663635 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein] CTD PMID:23112101 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; 2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; [2-tert-butylhydroquinone co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA; Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]
2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA; 2-tert-butylhydroquinone results in increased expression of HMOX1 protein
2-tert-butylhydroquinone inhibits the reaction [decamethrin results in increased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [decamethrin results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in increased expression of HMOX1 protein]; [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride; FGF1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of HMOX1 mRNA; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]
CTD PMID:8612205 PMID:10473555 PMID:10874044 PMID:10975858 PMID:16014739 PMID:16524372 PMID:17676812 PMID:18227147 PMID:18417180 PMID:18482591 PMID:18512965 PMID:19033392 PMID:19715681 PMID:21107535 PMID:21443188 PMID:22250088 PMID:22493042 PMID:22983789 PMID:23112101 PMID:23906629 PMID:23942037 PMID:23945499 PMID:24128855 PMID:24970285 PMID:25003661 PMID:25305463 PMID:26878773 PMID:26879219 PMID:28264691 PMID:28583816 PMID:28645578 PMID:29663635 PMID:30476502 PMID:30547568 PMID:31726083 PMID:32073640 PMID:32428544 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of HSD17B3 mRNA] CTD PMID:32565124 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of HSD3B1 mRNA] CTD PMID:32565124
G Hsf1 heat shock transcription factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of HSF1 mRNA CTD PMID:30309986 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein] CTD PMID:25341683 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Ifng interferon gamma multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Dinoprostone]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; 2-tert-butylhydroquinone results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of IFNG mRNA; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]] CTD PMID:22250088 PMID:23942037 PMID:30171972 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of IKBKB protein modified form] CTD PMID:28844481 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of IL10 mRNA]
2-tert-butylhydroquinone results in increased expression of IL10 mRNA
CTD PMID:32565124 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]] CTD PMID:25680285 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]] CTD PMID:25680285 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL13 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL13 mRNA CTD PMID:22250088 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il16 interleukin 16 increases secretion ISO 2-tert-butylhydroquinone results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 2-tert-butylhydroquinone results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of IL1B protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL1B protein] CTD PMID:28583816 PMID:28844481 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in decreased expression of IL2 mRNA
2-tert-butylhydroquinone results in decreased expression of and results in decreased secretion of IL2 protein
CTD PMID:23945499 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]] CTD PMID:25680285 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in decreased expression of IL2RA mRNA; 2-tert-butylhydroquinone results in decreased expression of IL2RA protein
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]
CTD PMID:23945499 PMID:30171972 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL4 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL4 mRNA CTD PMID:22250088 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein CTD PMID:22250088 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased secretion of IL6 protein]
2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL6 protein]
CTD PMID:25305463 PMID:28844481 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
ISO 2-tert-butylhydroquinone promotes the reaction [JUND protein binds to CYP2C9 promoter]; 2-tert-butylhydroquinone promotes the reaction [JUND protein modified form binds to CYP2C9 promoter]; JUND mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP2C9 mRNA]; pyrazolanthrone inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of JUND protein] CTD PMID:24830941 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
decreases response to substance
affects binding
ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]
2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in decreased expression of KEAP1 protein]
2-tert-butylhydroquinone results in increased expression of KEAP1 protein
KEAP1 protein mutant form results in decreased susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased activity of NFE2L2 protein; Cadmium Chloride inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]]
2-tert-butylhydroquinone binds to KEAP1 protein
CTD PMID:18417180 PMID:18512965 PMID:19033392 PMID:19808700 PMID:23589329 PMID:30261176 PMID:31368498 PMID:31726083 PMID:32073640 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of LHB protein] CTD PMID:32565124 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO 2-tert-butylhydroquinone results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of MAPK1 protein]
CTD PMID:24830941 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of MAPK3 protein] CTD PMID:24830941 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of MCHR1 mRNA CTD PMID:16014739 NCBI chr 7:122,456,846...122,459,324
Ensembl chr 7:122,456,799...122,459,960
JBrowse link
G Mfn2 mitofusin 2 multiple interactions
increases expression
EXP 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of MFN2 protein]
2-tert-butylhydroquinone results in increased expression of MFN2 protein
CTD PMID:31726083 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of MT1 mRNA
2-tert-butylhydroquinone promotes the reaction [Cycloheximide results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Zinc deficiency inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]
CTD PMID:14998373 PMID:19276070 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression ISO 2-tert-butylhydroquinone results in increased expression of MT2 mRNA CTD PMID:14998373 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA] CTD PMID:14998373 NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
JBrowse link
G Mtrf1 mitochondrial translation release factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of MTRF1 mRNA CTD PMID:16014739 NCBI chr15:61,662,000...61,689,867
Ensembl chr15:61,662,264...61,689,862
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects localization
increases response to substance
increases expression
increases activity
affects response to substance
decreases response to substance
increases ubiquitination
increases stability
affects binding
ISO
EXP
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]; 2-tert-butylhydroquinone affects the localization of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; 2-tert-butylhydroquinone results in increased expression of and affects the localization of NFE2L2 protein; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone results in increased stability of and affects the localization of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased susceptibility to arsenite; [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein] which results in decreased susceptibility to Oxidopamine; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; Metformin inhibits the reaction [2-tert-butylhydroquinone results in increased stability of and affects the localization of NFE2L2 protein]; NFE2L2 affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form]
2-tert-butylhydroquinone affects the localization of NFE2L2 protein
NFE2L2 protein mutant form results in increased susceptibility to 2-tert-butylhydroquinone
NFE2L2 protein affects the susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin affects the expression of and affects the localization of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to BCL2 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone results in increased expression of and affects the localization of NFE2L2 protein; [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased activity of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased activity of TBX21 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of IFNG mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL13 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL4 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL13 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL4 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in decreased expression of BAX protein; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in increased expression of BCL2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein]; Cadmium Chloride inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of BCL2 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitrites]]
2-tert-butylhydroquinone results in increased activity of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein
2-tert-butylhydroquinone affects the localization of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 protein]; [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride; [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; decamethrin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; N-acetylsphingosine inhibits the reaction [2-tert-butylhydroquinone results in increased localization of NFE2L2 protein]
NFE2L2 protein results in decreased susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone results in increased expression of NFE2L2 mRNA; 2-tert-butylhydroquinone results in increased expression of NFE2L2 protein
2-tert-butylhydroquinone binds to NFE2L2 protein
CTD PMID:10473555 PMID:10874044 PMID:12446695 PMID:14510636 PMID:14998373 PMID:15319326 PMID:15870285 PMID:16092930 PMID:17676812 PMID:18417180 PMID:18512965 PMID:18852027 PMID:19033392 PMID:19183254 PMID:19276070 PMID:19328227 PMID:19715681 PMID:19786557 PMID:20554019 PMID:20932822 PMID:21107535 PMID:21443188 PMID:21464371 PMID:22250088 PMID:22275372 PMID:22476201 PMID:22684020 PMID:22746536 PMID:22983789 PMID:23589329 PMID:23707609 PMID:23906629 PMID:23942037 PMID:23945499 PMID:24704207 PMID:25003661 PMID:25341683 PMID:25680285 PMID:26878773 PMID:26879219 PMID:26958860 PMID:28583816 PMID:28645578 PMID:28790194 PMID:28844481 PMID:29663635 PMID:29857117 PMID:30476502 PMID:30806763 PMID:31368498 PMID:31726083 PMID:32073640 PMID:32428544 PMID:32565124 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased phosphorylation of NFKBIA protein] CTD PMID:28583816 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of NKD1 mRNA CTD PMID:16014739 NCBI chr19:19,434,720...19,509,087
Ensembl chr19:19,436,333...19,509,087
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 protein] CTD PMID:32073640 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 decreases expression EXP 2-tert-butylhydroquinone results in decreased expression of NOTCH1 protein CTD PMID:29663635 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased activity of NQO1 protein
2-tert-butylhydroquinone results in increased expression of NQO1 mRNA; 2-tert-butylhydroquinone results in increased expression of NQO1 protein
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of NQO1 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; AG-879 inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Paraquat inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Zinc promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NQO1 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NQO1 protein]; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of NQO1 protein; [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 protein; Dexamethasone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NQO1 protein]; Dexamethasone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]; [lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA; [sodium arsenite co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA; [sodium arsenite co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 protein]; NFE2L2 affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA]
CTD PMID:7587946 PMID:9029048 PMID:11163336 PMID:14510636 PMID:14998373 PMID:15627257 PMID:16014739 PMID:16600132 PMID:17980396 PMID:18417180 PMID:18512965 PMID:19033392 PMID:19276070 PMID:20650352 PMID:21464371 PMID:22250088 PMID:22275372 PMID:22493042 PMID:23056183 PMID:23906629 PMID:23945499 PMID:24128855 PMID:24632381 PMID:24646717 PMID:24704207 PMID:24970285 PMID:25003661 PMID:25680285 PMID:26878773 PMID:28264691 PMID:28583816 PMID:28645578 PMID:29663635 PMID:30476502 PMID:30547568 PMID:30806763 PMID:31368498 PMID:31726083 PMID:32428544 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in decreased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of PCNA protein] CTD PMID:32565124 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO 2-tert-butylhydroquinone results in increased expression of PGD mRNA CTD PMID:16014739 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of PRDX1 mRNA CTD PMID:16014739 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prf1 perforin 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein] CTD PMID:30171972 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression ISO 2-tert-butylhydroquinone results in increased expression of PRKACA mRNA CTD PMID:16014739 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Procr protein C receptor increases expression ISO 2-tert-butylhydroquinone results in increased expression of PROCR mRNA CTD PMID:16014739 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] CTD PMID:23829535 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of PTGR1 mRNA CTD PMID:16014739 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of PTGS2 protein] CTD PMID:28583816 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases expression ISO 2-tert-butylhydroquinone results in increased expression of REL mRNA CTD PMID:16014739 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased activity of RELA protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA protein]
CTD PMID:28583816 PMID:28844481 PMID:32073640 PMID:32565124 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO 2-tert-butylhydroquinone results in increased expression of RORC mRNA CTD PMID:16014739 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC3A2 mRNA CTD PMID:19183254 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC40A1 mRNA CTD PMID:16014739 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC7A11 mRNA CTD PMID:19183254 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of SOD1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in decreased expression of SOD1 protein] CTD PMID:28844481 PMID:32565124 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of SOD2 mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of SOD2 mRNA
CTD PMID:32428544 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sqor sulfide quinone oxidoreductase increases expression ISO 2-tert-butylhydroquinone results in increased expression of SQOR mRNA CTD PMID:16014739 NCBI chr 3:114,894,944...114,939,375
Ensembl chr 3:114,900,343...114,939,370
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased expression of SQSTM1 protein
[thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of SQSTM1 protein
CTD PMID:23589329 PMID:31726083 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of SRC protein CTD PMID:23112101 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SRXN1 mRNA CTD PMID:16014739 PMID:22003191 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of STAR mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of STAR protein] CTD PMID:32565124 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased activity of TBX21 protein CTD PMID:22250088 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of TNF protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF protein]
CTD PMID:28583816 PMID:32073640 PMID:32565124 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein]; 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein]; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CSF1R protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of SRC protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of TOB1 mRNA CTD PMID:16014739 NCBI chr10:81,913,689...81,915,727
Ensembl chr10:81,913,689...81,915,716
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:12949356 PMID:16014739 PMID:30806763 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP 2-tert-butylhydroquinone results in increased expression of UGT1A1 mRNA CTD PMID:20650352 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression
increases activity
multiple interactions
EXP
ISO
2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA
2-tert-butylhydroquinone results in increased activity of UGT1A6 protein
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]
CTD PMID:10220484 PMID:12948865 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO 2-tert-butylhydroquinone results in increased expression of UGT1A9 mRNA CTD PMID:10220484 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases expression ISO 2-tert-butylhydroquinone results in increased expression of UGT2B7 mRNA CTD PMID:10220484 NCBI chr14:22,597,103...22,619,968 JBrowse link
6-decylubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone inhibits the reaction [Diclofenac results in increased activity of CASP3 protein] CTD PMID:14599462 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) increases metabolic processing
multiple interactions
EXP DHODH protein results in increased metabolism of 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone
A 771726 inhibits the reaction [DHODH protein results in increased metabolism of 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone]
CTD PMID:9802339 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
hydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) decreases expression ISO hydroquinone results in decreased expression of A4GALT mRNA CTD PMID:31256213 NCBI chr 7:124,085,832...124,110,440
Ensembl chr 7:124,085,834...124,089,385
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO hydroquinone results in increased expression of ABCC3 mRNA CTD PMID:31256213 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO hydroquinone results in decreased expression of ACE2 mRNA CTD PMID:31256213 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression ISO hydroquinone results in increased expression of ADAP2 mRNA CTD PMID:31256213 NCBI chr10:67,494,851...67,527,582
Ensembl chr10:67,494,984...67,526,426
JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO hydroquinone results in increased expression of ADPRH mRNA CTD PMID:31256213 NCBI chr11:64,861,772...64,868,112
Ensembl chr11:64,861,768...64,868,108
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein increases expression ISO hydroquinone results in increased expression of ADTRP mRNA CTD PMID:31256213 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO hydroquinone results in increased expression of AEN mRNA CTD PMID:23416264 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO hydroquinone results in decreased expression of AFAP1 mRNA CTD PMID:31256213 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 decreases expression ISO hydroquinone results in decreased expression of AGGF1 mRNA CTD PMID:31256213 NCBI chr 2:25,068,804...25,095,429
Ensembl chr 2:25,069,620...25,095,106
JBrowse link
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
increases expression
ISO
EXP
hydroquinone affects the localization of AHR protein
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]
CTD PMID:15935814 PMID:29935983 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression ISO hydroquinone results in increased expression of AIFM2 mRNA CTD PMID:31256213 NCBI chr20:31,329,047...31,353,548
Ensembl chr20:31,339,787...31,352,906
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO hydroquinone results in decreased expression of AKR1B10 mRNA CTD PMID:31256213 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17464197 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of hydroquinone CTD PMID:8831264 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO hydroquinone results in increased expression of ALDH1L2 mRNA CTD PMID:31256213 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO hydroquinone results in increased expression of ALDH2 mRNA CTD PMID:15452088 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO hydroquinone results in increased expression of ALDH3A1 mRNA CTD PMID:31256213 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO hydroquinone results in increased expression of ALOX12 mRNA CTD PMID:31256213 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO hydroquinone results in increased expression of ALOX12B mRNA CTD PMID:31256213 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 increases expression ISO hydroquinone results in increased expression of ALOXE3 mRNA CTD PMID:31256213 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Alpk1 alpha-kinase 1 increases expression ISO hydroquinone results in increased expression of ALPK1 mRNA CTD PMID:31256213 NCBI chr 2:231,997,360...232,117,471
Ensembl chr 2:231,996,088...232,117,134
JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO hydroquinone results in decreased expression of ANKDD1A mRNA CTD PMID:31256213 NCBI chr 8:71,034,630...71,057,265
Ensembl chr 8:71,035,309...71,055,969
JBrowse link
G Anxa1 annexin A1 increases expression ISO hydroquinone results in increased expression of ANXA1 mRNA CTD PMID:31256213 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa3 annexin A3 increases expression ISO hydroquinone results in increased expression of ANXA3 mRNA CTD PMID:31256213 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO hydroquinone results in decreased expression of AQP3 mRNA CTD PMID:31256213 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arg1 arginase 1 increases expression ISO hydroquinone results in increased expression of ARG1 mRNA CTD PMID:31256213 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 increases expression ISO hydroquinone results in increased expression of ARG2 mRNA CTD PMID:31256213 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO hydroquinone results in increased expression of ARHGAP27 mRNA CTD PMID:31256213 NCBI chr10:91,418,535...91,451,831
Ensembl chr10:91,419,912...91,448,477
JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO hydroquinone results in decreased expression of ARHGAP42 mRNA CTD PMID:31256213 NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha affects expression ISO hydroquinone affects the expression of ARHGDIA protein CTD PMID:17181942 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO hydroquinone results in increased expression of ARHGEF2 mRNA CTD PMID:31256213 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 decreases expression ISO hydroquinone results in decreased expression of ARHGEF26 mRNA CTD PMID:31256213 NCBI chr 2:27,107,263...27,236,336
Ensembl chr 2:27,107,318...27,236,672
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression ISO hydroquinone results in decreased expression of ARL3 mRNA CTD PMID:31256213 NCBI chr 1:266,287,015...266,333,099
Ensembl chr 1:266,287,017...266,333,105
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO hydroquinone results in increased expression of ASNS mRNA CTD PMID:31256213 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression ISO hydroquinone results in increased expression of ASPRV1 mRNA CTD PMID:31256213 NCBI chr 4:118,431,755...118,433,286
Ensembl chr 4:118,431,755...118,432,775
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO hydroquinone results in increased expression of ATF3 mRNA CTD PMID:31256213 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO hydroquinone results in increased expression of ATF4 mRNA CTD PMID:15452088 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
ISO PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA] CTD PMID:28263894 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 increases expression ISO hydroquinone results in increased expression of ATP2C2 mRNA CTD PMID:31256213 NCBI chr19:52,347,480...52,404,608
Ensembl chr19:52,347,580...52,404,607
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 increases expression ISO hydroquinone results in increased expression of ATP6V1C2 mRNA CTD PMID:31256213 NCBI chr 6:42,585,452...42,632,289
Ensembl chr 6:42,585,934...42,630,983
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding increases expression ISO hydroquinone results in increased expression of AZGP1 mRNA CTD PMID:31256213 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
affects localization
ISO [ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
hydroquinone affects the localization of BACH1 protein
CTD PMID:28645578 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO hydroquinone results in decreased expression of BAD mRNA CTD PMID:15452088 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO hydroquinone results in decreased expression of BAG1 mRNA CTD PMID:31256213 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO hydroquinone results in increased expression of BAMBI mRNA CTD PMID:31256213 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO hydroquinone results in increased expression of BBC3 mRNA CTD PMID:23416264 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO hydroquinone results in decreased expression of BCL11A mRNA CTD PMID:31256213 NCBI chr14:108,826,717...108,921,197
Ensembl chr14:108,826,831...108,921,669
JBrowse link
G Bcl11b BAF chromatin remodeling complex subunit BCL11B decreases expression ISO hydroquinone results in decreased expression of BCL11B mRNA CTD PMID:31256213 NCBI chr 6:131,834,097...131,927,251
Ensembl chr 6:131,834,097...131,926,272
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein CTD PMID:28444915 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO hydroquinone results in decreased expression of BDH2 mRNA CTD PMID:31256213 NCBI chr 2:240,461,505...240,482,149
Ensembl chr 2:240,461,505...240,482,145
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein
PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]
CTD PMID:28263894 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
decreases expression
ISO hydroquinone results in increased expression of BIRC3 mRNA
hydroquinone results in decreased expression of BIRC3 mRNA
CTD PMID:15452088 PMID:31256213 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]
CTD PMID:28886972 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO hydroquinone results in decreased expression of BNIP3 mRNA CTD PMID:15452088 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO hydroquinone results in decreased expression of BORA mRNA CTD PMID:23416264 NCBI chr15:83,442,217...83,463,737
Ensembl chr15:83,442,144...83,463,717
JBrowse link
G Bpifc BPI fold containing family C increases expression ISO hydroquinone results in increased expression of BPIFC mRNA CTD PMID:31256213 NCBI chr 7:23,854,846...23,911,953
Ensembl chr 7:23,854,846...23,911,953
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO hydroquinone results in increased expression of BRCA1 protein CTD PMID:29421518 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO hydroquinone results in decreased expression of BST2 mRNA CTD PMID:31256213 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO hydroquinone results in increased expression of BTG2 mRNA CTD PMID:23416264 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO hydroquinone results in decreased expression of BUB3 mRNA CTD PMID:31256213 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO hydroquinone results in decreased expression of CA3 mRNA CTD PMID:31256213 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO hydroquinone results in decreased expression of CA9 mRNA CTD PMID:31256213 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calb2 calbindin 2 increases expression ISO hydroquinone results in increased expression of CALB2 mRNA CTD PMID:31256213 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression ISO hydroquinone results in increased expression of CALCB mRNA CTD PMID:31256213 NCBI chr 1:184,271,116...184,276,480
Ensembl chr 1:184,271,590...184,276,475
JBrowse link
G Calhm6 calcium homeostasis modulator family member 6 decreases expression ISO hydroquinone results in decreased expression of CALHM6 mRNA CTD PMID:31256213 NCBI chr20:27,681,138...27,683,580
Ensembl chr20:27,681,036...27,682,861
JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO hydroquinone results in decreased expression of CALML3 mRNA CTD PMID:31256213 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530
JBrowse link
G Capn2 calpain 2 decreases activity ISO hydroquinone results in decreased activity of CAPN2 protein CTD PMID:9118890 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
decreases activity
decreases expression
ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]
hydroquinone results in increased cleavage of CASP3 protein
hydroquinone results in decreased activity of CASP3 protein
[hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein
hydroquinone results in decreased expression of CASP3 mRNA
CTD PMID:15337166 PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 PMID:22960397 PMID:23776099 PMID:28444915 PMID:28886972 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 decreases expression ISO hydroquinone results in decreased expression of CASP6 mRNA CTD PMID:15452088 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 increases cleavage
increases expression
decreases activity
multiple interactions
ISO hydroquinone results in increased cleavage of CASP7 protein
hydroquinone results in increased expression of CASP7 protein modified form
hydroquinone results in decreased activity of CASP7 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]
CTD PMID:19064679 PMID:22960397 PMID:28886972 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
hydroquinone results in increased activity of CASP8 protein
CTD PMID:15777082 PMID:23776099 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 decreases expression
multiple interactions
increases expression
increases activity
increases cleavage
ISO hydroquinone results in decreased expression of CASP9 mRNA
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]
hydroquinone results in increased activity of CASP9 protein
hydroquinone results in increased cleavage of CASP9 protein
CTD PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 PMID:23776099 PMID:28886972 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases response to substance ISO CAT protein results in decreased susceptibility to hydroquinone CTD PMID:10193577 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO hydroquinone results in decreased expression of CAVIN2 mRNA CTD PMID:31256213 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cbs cystathionine beta synthase increases expression ISO hydroquinone results in increased expression of CBS mRNA CTD PMID:31256213 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO hydroquinone results in decreased expression of CCDC127 mRNA CTD PMID:31256213 NCBI chr 1:31,538,088...31,545,573
Ensembl chr 1:31,539,215...31,545,559
JBrowse link
G Ccdc163 coiled-coil domain containing 163 decreases expression ISO hydroquinone results in decreased expression of CCDC163 mRNA CTD PMID:31256213 NCBI chr 5:135,562,034...135,568,067
Ensembl chr 5:135,562,034...135,568,062
JBrowse link
G Ccdc8 coiled-coil domain containing 8 decreases expression ISO hydroquinone results in decreased expression of CCDC8 mRNA CTD PMID:31256213 NCBI chr 1:78,933,372...78,936,700
Ensembl chr 1:78,933,372...78,936,700
JBrowse link
G Ccdc88c coiled-coil domain containing 88C decreases expression ISO hydroquinone results in decreased expression of CCDC88C mRNA CTD PMID:31256213 NCBI chr 6:124,905,811...125,028,011
Ensembl chr 6:124,905,808...125,027,553
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO hydroquinone results in increased expression of CCL11 protein CTD PMID:17572062 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion
decreases expression
multiple interactions
increases secretion
increases expression
ISO hydroquinone results in decreased secretion of CCL2 protein
hydroquinone results in decreased expression of CCL2 mRNA
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein]
hydroquinone results in increased secretion of CCL2 protein
hydroquinone results in increased expression of CCL2 protein
CTD PMID:17572062 PMID:20946948 PMID:22302391 PMID:22465845 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO hydroquinone results in increased expression of CCL3 protein CTD PMID:17572062 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO hydroquinone results in increased expression of CCL4 protein CTD PMID:17572062 PMID:18353026 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO hydroquinone results in increased expression of CCL5 protein CTD PMID:17572062 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO hydroquinone affects the expression of CCN1 mRNA CTD PMID:15452088 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna1 cyclin A1 increases expression ISO hydroquinone results in increased expression of CCNA1 mRNA CTD PMID:31256213 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein] CTD PMID:28886972 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne2 cyclin E2 increases expression ISO hydroquinone results in increased expression of CCNE2 mRNA CTD PMID:23416264 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccnf cyclin F decreases expression ISO hydroquinone results in decreased expression of CCNF mRNA CTD PMID:23416264 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Ccsap centriole, cilia and spindle-associated protein decreases expression ISO hydroquinone results in decreased expression of CCSAP mRNA CTD PMID:31256213 NCBI chr19:56,615,326...56,634,031
Ensembl chr19:56,617,399...56,633,633
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein] CTD PMID:20054000 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:19148301 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule increases expression
multiple interactions
ISO hydroquinone results in increased expression of CD86 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]
CTD PMID:19148301 PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO hydroquinone results in decreased expression of CDCA2 mRNA CTD PMID:23416264 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO hydroquinone results in decreased expression of CDCA7 mRNA CTD PMID:31256213 NCBI chr 3:59,153,281...59,163,916
Ensembl chr 3:59,153,280...59,163,913
JBrowse link
G Cdh26 cadherin 26 decreases expression ISO hydroquinone results in decreased expression of CDH26 mRNA CTD PMID:31256213 NCBI chr 3:173,969,004...174,020,867
Ensembl chr 3:173,969,273...174,019,766
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO hydroquinone results in increased expression of CDKN1A mRNA CTD PMID:23416264 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO hydroquinone results in decreased expression of CDKN1C mRNA CTD PMID:31256213 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdsn corneodesmosin increases expression ISO hydroquinone results in increased expression of CDSN mRNA CTD PMID:31256213 NCBI chr20:3,704,626...3,707,266 JBrowse link
G Cemip cell migration inducing hyaluronidase increases expression ISO hydroquinone results in increased expression of CEMIP mRNA CTD PMID:31256213 NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462
JBrowse link
G Cenpa centromere protein A decreases expression ISO hydroquinone results in decreased expression of CENPA mRNA CTD PMID:23416264 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO hydroquinone results in increased expression of CES1 mRNA CTD PMID:31256213 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cfap44 cilia and flagella associated protein 44 decreases expression ISO hydroquinone results in decreased expression of CFAP44 mRNA CTD PMID:31256213 NCBI chr11:61,160,793...61,237,056
Ensembl chr11:61,162,628...61,234,944
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO hydroquinone results in increased expression of CFLAR mRNA CTD PMID:31256213 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO hydroquinone results in increased expression of CH25H mRNA CTD PMID:31256213 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO hydroquinone results in increased expression of CHAC1 mRNA CTD PMID:31256213 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 decreases expression ISO hydroquinone results in decreased expression of CHP2 mRNA CTD PMID:31256213 NCBI chr 1:192,169,634...192,173,228
Ensembl chr 1:192,169,841...192,173,253
JBrowse link
G Chst2 carbohydrate sulfotransferase 2 increases expression ISO hydroquinone results in increased expression of CHST2 mRNA CTD PMID:31256213 NCBI chr 8:103,186,759...103,190,612
Ensembl chr 8:103,188,651...103,190,243
JBrowse link
G Clca4 chloride channel accessory 4 decreases expression ISO hydroquinone results in decreased expression of CLCA4 mRNA CTD PMID:31256213 NCBI chr 2:250,842,939...250,864,060
Ensembl chr 2:250,843,165...250,862,419
JBrowse link
G Cldn8 claudin 8 decreases expression ISO hydroquinone results in decreased expression of CLDN8 mRNA CTD PMID:31256213 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO hydroquinone results in increased expression of CLIC3 mRNA CTD PMID:31256213 NCBI chr 3:2,675,732...2,678,248
Ensembl chr 3:2,676,296...2,680,565
JBrowse link
G Clmp CXADR-like membrane protein increases expression ISO hydroquinone results in increased expression of CLMP mRNA CTD PMID:31256213 NCBI chr 8:44,846,685...44,975,460
Ensembl chr 8:44,847,157...44,975,457
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO hydroquinone results in decreased expression of CMPK2 mRNA CTD PMID:31256213 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cnfn cornifelin increases expression ISO hydroquinone results in increased expression of CNFN mRNA CTD PMID:31256213 NCBI chr 1:82,234,032...82,236,602
Ensembl chr 1:82,234,032...82,236,179
JBrowse link
G Cnmd chondromodulin increases response to substance
increases expression
multiple interactions
ISO CNMD protein results in increased susceptibility to hydroquinone
hydroquinone results in increased expression of CNMD mRNA
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]
CTD PMID:19525446 NCBI chr15:61,923,291...61,947,840
Ensembl chr15:61,923,299...61,947,764
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO hydroquinone results in increased expression of COL1A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]
CTD PMID:18055817 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein CTD PMID:29908986 PMID:29935983 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
increases expression
multiple interactions
ISO hydroquinone results in decreased expression of COL4A1 mRNA
hydroquinone results in increased expression of COL4A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]
CTD PMID:18055817 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO hydroquinone results in decreased expression of COL5A2 mRNA CTD PMID:31256213 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Crct1 cysteine-rich C-terminal 1 increases expression ISO hydroquinone results in increased expression of CRCT1 mRNA CTD PMID:31256213 Ensembl chr 2:193,330,397...193,330,699 JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO hydroquinone results in increased expression of CRISPLD2 mRNA CTD PMID:31256213 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein
hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]
CTD PMID:7884313 PMID:15129224 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 increases expression ISO hydroquinone results in increased expression of CSGALNACT1 mRNA CTD PMID:31256213 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 decreases expression ISO hydroquinone results in decreased expression of CSRNP3 mRNA CTD PMID:31256213 NCBI chr 3:51,883,559...52,120,290
Ensembl chr 3:51,883,559...52,120,290
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO hydroquinone results in decreased expression of CSRP2 mRNA CTD PMID:31256213 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cst6 cystatin E/M increases expression ISO hydroquinone results in increased expression of CST6 mRNA CTD PMID:31256213 NCBI chr 1:220,727,292...220,729,000
Ensembl chr 1:220,727,292...220,729,000
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO hydroquinone results in increased expression of CTH mRNA CTD PMID:31256213 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
decreases expression
ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein] CTD PMID:28886972 PMID:30567741 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO hydroquinone results in decreased expression of CXCL12 mRNA CTD PMID:22960397 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO hydroquinone affects the localization of CYCS protein CTD PMID:15777082 PMID:15816534 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects response to substance
increases expression
ISO CYP1A1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of CYP1A1 mRNA
CTD PMID:8242868 PMID:23416264 PMID:31256213 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone CTD PMID:8211999 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects response to substance ISO CYP2B1 protein affects the susceptibility to hydroquinone CTD PMID:8242868 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP
ISO
[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]
hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]
CTD PMID:8211999 PMID:15051535 PMID:30567741 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO [CYP3A4 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO hydroquinone results in increased expression of CYP4F18 mRNA CTD PMID:23940708 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cysrt1 cysteine rich tail 1 increases expression ISO hydroquinone results in increased expression of CYSRT1 mRNA CTD PMID:31256213 NCBI chr 3:2,458,295...2,462,037
Ensembl chr 3:2,458,295...2,459,385
JBrowse link
G Dap death-associated protein decreases expression ISO hydroquinone results in decreased expression of DAP mRNA CTD PMID:15452088 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dapl1 death associated protein-like 1 decreases expression ISO hydroquinone results in decreased expression of DAPL1 mRNA CTD PMID:31256213 NCBI chr 3:45,538,408...45,559,281
Ensembl chr 3:45,538,797...45,559,331
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO hydroquinone results in increased expression of DAPP1 mRNA CTD PMID:31256213 NCBI chr 2:243,175,346...243,224,883
Ensembl chr 2:243,175,346...243,224,883
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO hydroquinone results in decreased expression of DBT mRNA CTD PMID:31256213 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 increases expression ISO hydroquinone results in increased expression of DCUN1D3 mRNA CTD PMID:31256213 NCBI chr 1:189,626,442...189,666,440
Ensembl chr 1:189,627,972...189,666,440
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO hydroquinone results in decreased expression of DDAH1 mRNA CTD PMID:31256213 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO hydroquinone results in increased expression of DDIT3 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO hydroquinone results in increased expression of DDIT4 mRNA CTD PMID:23416264 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO hydroquinone results in decreased expression of DEPDC7 mRNA CTD PMID:31256213 NCBI chr 3:94,665,714...94,687,013
Ensembl chr 3:94,665,717...94,686,989
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO hydroquinone results in decreased expression of DFFB mRNA CTD PMID:31256213 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression ISO hydroquinone affects the expression of DKK1 mRNA CTD PMID:22960397 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO hydroquinone results in increased expression of DNAJA1 mRNA CTD PMID:15452088 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:15452088 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dner delta/notch-like EGF repeat containing decreases expression ISO hydroquinone results in decreased expression of DNER mRNA CTD PMID:31256213 NCBI chr 9:91,965,866...92,291,172
Ensembl chr 9:91,965,866...92,291,220
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
affects expression
ISO hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein
hydroquinone affects the expression of DNMT1 mRNA
CTD PMID:22245671 PMID:27979589 PMID:31899212 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein
hydroquinone results in increased expression of DNMT3A mRNA
CTD PMID:22245671 PMID:27979589 PMID:31899212 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
affects expression
ISO hydroquinone results in decreased expression of DNMT3B mRNA
Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]
CTD PMID:22245671 PMID:31899212 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO hydroquinone results in decreased expression of DTX3L mRNA CTD PMID:31256213 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622
JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO hydroquinone results in decreased expression of DUSP19 mRNA CTD PMID:31256213 NCBI chr 3:67,849,966...67,862,475
Ensembl chr 3:67,849,966...67,862,475
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO hydroquinone results in increased expression of DUSP5 mRNA CTD PMID:31256213 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO hydroquinone results in increased expression of DUSP6 mRNA CTD PMID:31256213 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 decreases expression ISO hydroquinone results in decreased expression of DZIP1 mRNA CTD PMID:31256213 NCBI chr15:104,117,551...104,168,574
Ensembl chr15:104,117,556...104,170,958
JBrowse link
G E4f1 E4F transcription factor 1 increases expression
affects response to substance
multiple interactions
ISO hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein
E4F1 protein affects the susceptibility to hydroquinone
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form
CTD PMID:30448557 PMID:30506647 NCBI chr10:13,812,335...13,835,847
Ensembl chr10:13,815,293...13,826,945
JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO hydroquinone results in increased expression of ECM2 mRNA CTD PMID:31256213 NCBI chr17:15,533,760...15,566,403
Ensembl chr17:15,533,972...15,566,332
JBrowse link
G Edn1 endothelin 1 decreases expression ISO hydroquinone results in decreased expression of EDN1 mRNA CTD PMID:31256213 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 decreases expression ISO hydroquinone results in decreased expression of EDN2 mRNA CTD PMID:31256213 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO hydroquinone results in decreased expression of EEF2K mRNA CTD PMID:31256213 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324
JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA CTD PMID:32198055 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Egr3 early growth response 3 increases expression ISO hydroquinone results in increased expression of EGR3 mRNA CTD PMID:31256213 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO hydroquinone results in decreased expression of EHMT2 protein CTD PMID:27979589 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 decreases expression ISO hydroquinone results in decreased expression of EID3 mRNA CTD PMID:31256213 NCBI chr 7:26,976,154...26,977,479 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO hydroquinone results in increased expression of EIF4EBP1 mRNA CTD PMID:31256213 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO hydroquinone results in increased expression of ELF3 mRNA CTD PMID:23416264 NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
JBrowse link
G Elf5 E74 like ETS transcription factor 5 increases expression ISO hydroquinone results in increased expression of ELF5 mRNA CTD PMID:31256213 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Elmod1 ELMO domain containing 1 increases expression ISO hydroquinone results in increased expression of ELMOD1 mRNA CTD PMID:31256213 NCBI chr 8:58,486,078...58,542,884
Ensembl chr 8:58,486,078...58,542,844
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO hydroquinone results in increased expression of ELOVL4 mRNA CTD PMID:31256213 NCBI chr 8:91,310,690...91,338,625
Ensembl chr 8:91,310,630...91,338,843
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO hydroquinone results in decreased expression of ELOVL5 mRNA CTD PMID:31256213 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 decreases expression ISO hydroquinone results in decreased expression of ELP2 mRNA CTD PMID:31256213 NCBI chr18:16,544,515...16,581,086
Ensembl chr18:16,544,508...16,581,116
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression ISO hydroquinone results in increased expression of EPB41L3 mRNA CTD PMID:31256213 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO hydroquinone results in increased expression of EPS8L1 mRNA CTD PMID:31256213 NCBI chr 1:72,926,106...72,942,433
Ensembl chr 1:72,927,151...72,941,869
JBrowse link
G Ereg epiregulin increases expression ISO hydroquinone results in increased expression of EREG mRNA CTD PMID:31256213 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Erich5 glutamate-rich 5 decreases expression ISO hydroquinone results in decreased expression of ERICH5 mRNA CTD PMID:31256213 NCBI chr 7:73,222,331...73,243,684
Ensembl chr 7:73,222,730...73,242,899
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO hydroquinone results in decreased expression of ESR1 mRNA CTD PMID:31256213 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression ISO hydroquinone results in increased expression of ETV4 mRNA CTD PMID:31256213 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Exosc3 exosome component 3 decreases expression ISO hydroquinone results in decreased expression of EXOSC3 mRNA CTD PMID:31256213 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc6 exosome component 6 increases expression ISO hydroquinone results in increased expression of EXOSC6 mRNA CTD PMID:31256213 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO hydroquinone results in decreased expression of EZH2 protein CTD PMID:27979589 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO hydroquinone results in decreased expression of F2R mRNA CTD PMID:31256213 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO hydroquinone results in decreased expression of FADD mRNA CTD PMID:15452088 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fam117b family with sequence similarity 117, member B decreases expression ISO hydroquinone results in decreased expression of FAM117B mRNA CTD PMID:31256213 NCBI chr 9:66,716,969...66,784,487
Ensembl chr 9:66,716,969...66,784,487
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO hydroquinone results in decreased expression of FAM13A mRNA CTD PMID:31256213 NCBI chr 4:89,183,180...89,281,282
Ensembl chr 4:89,183,768...89,281,222
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO hydroquinone results in increased expression of FAM43A mRNA CTD PMID:31256213 NCBI chr11:73,676,601...73,679,003
Ensembl chr11:73,676,601...73,678,984
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO hydroquinone results in decreased expression of FAM83D mRNA CTD PMID:23416264 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO hydroquinone results in increased expression of FAS protein
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein
CTD PMID:23776099 PMID:28444915 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO hydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO hydroquinone results in decreased expression of FBXO5 mRNA CTD PMID:23416264 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO hydroquinone results in decreased expression of FGFR3 mRNA CTD PMID:31256213 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO hydroquinone results in increased expression of FIBIN mRNA CTD PMID:31256213 NCBI chr 3:101,545,207...101,547,478
Ensembl chr 3:101,545,208...101,547,478
JBrowse link
G Fn1 fibronectin 1 affects expression ISO hydroquinone affects the expression of FN1 mRNA CTD PMID:15452088 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO hydroquinone results in decreased expression of FOS mRNA CTD PMID:15452088 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO hydroquinone results in increased expression of FOSL1 mRNA CTD PMID:31256213 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fry FRY microtubule binding protein increases expression ISO hydroquinone results in increased expression of FRY mRNA CTD PMID:31256213 NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
JBrowse link
G Fsip1 fibrous sheath interacting protein 1 increases expression ISO hydroquinone results in increased expression of FSIP1 mRNA CTD PMID:31256213 NCBI chr 3:109,877,943...110,021,186
Ensembl chr 3:109,969,152...110,021,149
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO hydroquinone results in increased expression of FTH1 mRNA CTD PMID:15452088 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO hydroquinone results in decreased expression of FZD2 mRNA CTD PMID:31256213 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO hydroquinone results in increased expression of G0S2 mRNA CTD PMID:31256213 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO hydroquinone results in increased expression of GADD45A mRNA CTD PMID:23416264 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO hydroquinone results in decreased expression of GAS1 mRNA CTD PMID:31256213 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO hydroquinone results in decreased expression of GASK1B mRNA CTD PMID:31256213 NCBI chr 2:178,678,946...178,751,459
Ensembl chr 2:178,679,041...178,750,668
JBrowse link
G Gata1 GATA binding protein 1 decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of GATA1 mRNA
decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
CTD PMID:21414390 PMID:23973255 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression
ISO hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroquinone results in decreased expression of GATA2 mRNA
CTD PMID:21414390 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO hydroquinone results in decreased expression of GBP2 mRNA CTD PMID:31256213 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein CTD PMID:30547568 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein CTD PMID:21059386 PMID:30547568 PMID:31256213 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gda guanine deaminase increases expression ISO hydroquinone results in increased expression of GDA mRNA CTD PMID:31256213 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO hydroquinone results in increased expression of GDPD3 mRNA CTD PMID:31256213 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO hydroquinone results in increased expression of GFPT1 mRNA CTD PMID:31256213 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Gk glycerol kinase increases expression ISO hydroquinone results in increased expression of GK mRNA CTD PMID:31256213 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression ISO hydroquinone results in decreased expression of GLMP mRNA CTD PMID:31256213 NCBI chr 2:187,697,528...187,701,118
Ensembl chr 2:187,697,523...187,701,118
JBrowse link
G Glrx glutaredoxin increases expression ISO hydroquinone results in increased expression of GLRX mRNA CTD PMID:31256213 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO hydroquinone results in decreased expression of GLUL mRNA CTD PMID:31256213 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO hydroquinone results in decreased expression of GMPR mRNA CTD PMID:31256213 NCBI chr17:19,543,274...19,580,929
Ensembl chr17:19,543,275...19,580,929
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO hydroquinone results in decreased expression of GOSR2 mRNA CTD PMID:31256213 NCBI chr10:91,735,772...91,756,123
Ensembl chr10:91,736,780...91,756,081
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO hydroquinone results in increased expression of GOT1 mRNA CTD PMID:31256213 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO hydroquinone results in increased expression of GPAT3 mRNA CTD PMID:31256213 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO hydroquinone results in decreased expression of GPR155 mRNA CTD PMID:31256213 NCBI chr 3:60,051,545...60,105,567
Ensembl chr 3:60,051,535...60,105,242
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO hydroquinone results in decreased expression of GPRC5A mRNA CTD PMID:31256213 NCBI chr 4:168,832,937...168,851,650
Ensembl chr 4:168,832,910...168,851,652
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO hydroquinone results in increased expression of GPX2 mRNA CTD PMID:31256213 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO hydroquinone results in increased expression of GRB10 mRNA CTD PMID:31256213 NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression ISO hydroquinone affects the expression of GRB2 protein CTD PMID:20021034 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO hydroquinone results in increased expression of GRHL1 mRNA CTD PMID:31256213 NCBI chr 6:43,734,837...43,795,757
Ensembl chr 6:43,743,702...43,794,342
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein] CTD PMID:28886972 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein] CTD PMID:15831208 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions
ISO hydroquinone results in increased expression of GSS protein
NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]
CTD PMID:21059386 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to hydroquinone CTD PMID:15141365 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gtpbp2 GTP binding protein 2 increases expression ISO hydroquinone results in increased expression of GTPBP2 mRNA CTD PMID:31256213 NCBI chr 9:17,198,957...17,208,456
Ensembl chr 9:17,198,957...17,209,220
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO hydroquinone results in increased expression of GUCY1B1 mRNA CTD PMID:31256213 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gvin1 GTPase, very large interferon inducible 1 decreases expression ISO hydroquinone results in decreased expression of GVINP1 mRNA CTD PMID:31256213 NCBI chr 1:173,233,675...173,259,901
Ensembl chr 1:173,252,058...173,259,702
JBrowse link
G Gypa glycophorin A decreases expression ISO hydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr19:31,115,545...31,131,079 JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-4 mRNA CTD PMID:23416264 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-5 mRNA CTD PMID:23416264 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO hydroquinone results in decreased expression of H2AC12 mRNA CTD PMID:23416264 NCBI chr17:44,527,990...44,528,557
Ensembl chr17:44,528,125...44,528,511
JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression ISO hydroquinone results in decreased expression of H2AC20 mRNA CTD PMID:23416264 NCBI chr 2:198,360,271...198,360,735
Ensembl chr 2:198,360,301...198,360,678
JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO hydroquinone results in decreased expression of H2AC21 mRNA CTD PMID:23416264 NCBI chr 2:198,359,754...198,360,146
Ensembl chr 2:198,359,754...198,360,146
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
affects localization
increases expression
ISO [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [POLH mutant form results in increased susceptibility to hydroquinone] which results in increased expression of H2AX protein; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
hydroquinone results in increased phosphorylation of H2AX protein
hydroquinone affects the localization of H2AX protein modified form
CTD PMID:17875398 PMID:18835433 PMID:20036648 PMID:21267443 PMID:22981619 PMID:30506647 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO hydroquinone results in decreased expression of H4C3 mRNA CTD PMID:23416264 NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-3 mRNA CTD PMID:23416264 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA] CTD PMID:21414390 PMID:23973255 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO hydroquinone results in increased expression of HBEGF mRNA CTD PMID:31256213 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO hydroquinone results in increased expression of HDAC1 protein CTD PMID:30448557 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 increases expression ISO hydroquinone results in increased expression of HDAC2 protein CTD PMID:30448557 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO hydroquinone results in increased expression of HDAC9 mRNA CTD PMID:31256213 NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
JBrowse link
G Hfe homeostatic iron regulator decreases expression ISO hydroquinone results in decreased expression of HFE mRNA CTD PMID:31256213 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hist1h4m histone cluster 1, H4m decreases expression ISO hydroquinone results in decreased expression of H4C1 mRNA CTD PMID:23416264 Ensembl chr17:44,815,684...44,815,995 JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 decreases expression ISO hydroquinone results in decreased expression of H2AC18 mRNA CTD PMID:23416264 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression ISO hydroquinone results in decreased expression of H4C2 mRNA CTD PMID:23416264 NCBI chr 2:198,411,955...198,412,350
Ensembl chr 2:198,411,955...198,412,350
JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO hydroquinone results in decreased expression of HJURP mRNA CTD PMID:23416264 NCBI chr 9:95,347,739...95,362,228
Ensembl chr 9:95,349,086...95,362,014
JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 PMID:23973255 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO hydroquinone results in decreased expression of HMGB2 mRNA CTD PMID:23416264 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of HMOX1 mRNA
ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]
hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein
CTD PMID:17464197 PMID:21059386 PMID:28645578 PMID:29508652 PMID:30547568 PMID:31256213 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hotairm1 Hoxa transcript antisense RNA, myeloid-specific 1 multiple interactions
affects expression
affects methylation
ISO Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter] CTD PMID:31899212 NCBI chr 4:82,127,355...82,130,853 JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
affects expression
ISO 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]
hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein
CTD PMID:26047893 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO hydroquinone results in increased expression of HSD17B2 mRNA CTD PMID:31256213 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression ISO hydroquinone results in increased expression of HSPA13 mRNA CTD PMID:31256213 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO hydroquinone results in increased expression of HSPA2 mRNA CTD PMID:15452088 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO hydroquinone results in decreased expression of HYLS1 mRNA CTD PMID:23416264 NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO hydroquinone results in increased expression of ID1 mRNA CTD PMID:31256213 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO hydroquinone results in decreased expression of ID3 mRNA CTD PMID:31256213 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein increases expression ISO hydroquinone results in increased expression of ID4 mRNA CTD PMID:31256213 NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
JBrowse link
G Ier3 immediate early response 3 increases expression ISO hydroquinone results in increased expression of IER3 mRNA CTD PMID:31256213 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO hydroquinone results in decreased expression of IFI44 mRNA CTD PMID:31256213 NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO hydroquinone results in decreased expression of IFI44L mRNA CTD PMID:31256213 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO hydroquinone results in decreased expression of IFIH1 mRNA CTD PMID:31256213 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO hydroquinone results in decreased expression of IFIT3 mRNA CTD PMID:31256213 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma multiple interactions ISO hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:3137358 PMID:7884313 PMID:22465845 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO hydroquinone results in increased expression of IFRD1 mRNA CTD PMID:31256213 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form] CTD PMID:28886972 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO hydroquinone results in decreased expression of IGFBP3 mRNA CTD PMID:31256213 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]
CTD PMID:17464197 PMID:17572062 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
hydroquinone results in increased expression of IL12B mRNA
CTD PMID:15894107 PMID:17464197 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A increases secretion EXP hydroquinone results in increased secretion of IL17A protein CTD PMID:29935983 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
decreases cleavage
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]
hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein
hydroquinone results in decreased cleavage of IL1A protein
CTD PMID:1868253 PMID:8548860 PMID:9118901 PMID:28836394 PMID:31256213 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta decreases cleavage
increases expression
decreases secretion
multiple interactions
ISO
EXP
hydroquinone results in decreased cleavage of IL1B protein
hydroquinone results in increased expression of IL1B mRNA
hydroquinone results in decreased secretion of IL1B protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:8548860 PMID:9118901 PMID:17464197 PMID:19148301 PMID:22717997 PMID:29908986 PMID:31256213 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1f10 interleukin 1 family member 10 increases expression ISO hydroquinone results in increased expression of IL1F10 mRNA CTD PMID:31256213 NCBI chr 3:1,408,560...1,416,601
Ensembl chr 3:1,413,671...1,416,599
JBrowse link
G Il2 interleukin 2 multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] CTD PMID:9571986 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA] CTD PMID:17464197 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il33 interleukin 33 decreases expression ISO hydroquinone results in decreased expression of IL33 mRNA CTD PMID:31256213 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il36g interleukin 36, gamma increases expression ISO hydroquinone results in increased expression of IL36G mRNA CTD PMID:31256213 NCBI chr 3:1,285,658...1,291,836
Ensembl chr 3:1,285,664...1,291,865
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO hydroquinone results in increased expression of IL36RN mRNA CTD PMID:31256213 NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275
JBrowse link
G Il4 interleukin 4 multiple interactions ISO hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein] CTD PMID:12153512 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
EXP
ISO
[COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone results in decreased secretion of IL6 protein
CTD PMID:17464197 PMID:19148301 PMID:20054000 PMID:22302391 PMID:22717997 PMID:29935983 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO hydroquinone results in increased expression of INHBA mRNA CTD PMID:31256213 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO hydroquinone results in increased expression of INPP4B mRNA CTD PMID:31256213 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO hydroquinone results in decreased expression of IRS1 mRNA CTD PMID:31256213 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO hydroquinone results in decreased expression of ISG15 mRNA CTD PMID:31256213 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgb1 integrin subunit beta 1 decreases activity
decreases expression
ISO hydroquinone results in decreased activity of ITGB1 protein
hydroquinone results in decreased expression of ITGB1 mRNA
hydroquinone results in decreased expression of ITGB1 protein
CTD PMID:17464197 PMID:19148301 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
increases expression
ISO hydroquinone results in decreased expression of ITGB2 protein
hydroquinone results in decreased expression of ITGB2 mRNA
hydroquinone results in increased expression of ITGB2 protein
CTD PMID:17464197 PMID:19148301 PMID:21664406 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroquinone results in increased expression of ITGB3 protein CTD PMID:21664406 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Ivl involucrin increases expression ISO hydroquinone results in increased expression of IVL mRNA CTD PMID:31256213 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO hydroquinone results in decreased expression of JAG1 mRNA CTD PMID:22960397 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jrk Jrk helix-turn-helix protein decreases expression ISO hydroquinone results in decreased expression of JRK mRNA CTD PMID:31256213 NCBI chr 7:115,941,788...115,946,471
Ensembl chr 7:115,942,743...115,946,425
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization ISO hydroquinone affects the localization of JUN protein CTD PMID:26807887 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 decreases expression ISO hydroquinone results in decreased expression of KBTBD6 mRNA CTD PMID:31256213 NCBI chr15:61,731,574...61,733,331
Ensembl chr15:61,731,735...61,733,742
JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 decreases expression ISO hydroquinone results in decreased expression of KBTBD7 mRNA CTD PMID:31256213 NCBI chr15:61,692,041...61,696,506 JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO hydroquinone results in decreased expression of KCNJ15 mRNA CTD PMID:31256213 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390
JBrowse link
G Kdm6a lysine demethylase 6A decreases expression ISO hydroquinone results in decreased expression of KDM6A mRNA CTD PMID:31256213 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Kics2 KICSTOR subunit 2 decreases expression ISO hydroquinone results in decreased expression of C12ORF66 mRNA CTD PMID:31256213 NCBI chr 7:63,922,871...63,937,721
Ensembl chr 7:63,922,879...63,936,385
JBrowse link
G Kif18a kinesin family member 18A decreases expression ISO hydroquinone results in decreased expression of KIF18A mRNA CTD PMID:23416264 NCBI chr 3:100,366,168...100,426,867
Ensembl chr 3:100,366,168...100,427,030
JBrowse link
G Kitlg KIT ligand increases expression ISO hydroquinone results in increased expression of KITLG mRNA CTD PMID:22960397 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression ISO hydroquinone results in increased expression of KLF2 mRNA CTD PMID:31256213 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf7 Kruppel like factor 7 increases expression ISO hydroquinone results in increased expression of KLF7 mRNA CTD PMID:31256213 NCBI chr 9:70,740,480...70,787,913
Ensembl chr 9:70,740,480...70,787,913
JBrowse link
G Klhl31 kelch-like family member 31 decreases expression ISO hydroquinone results in decreased expression of KLHL31 mRNA CTD PMID:31256213 NCBI chr 8:84,945,444...84,968,811
Ensembl chr 8:84,945,444...84,968,811
JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression ISO hydroquinone results in increased expression of KLK6 mRNA CTD PMID:31256213 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO hydroquinone results in decreased expression of KLRG2 mRNA CTD PMID:31256213 NCBI chr 4:66,370,674...66,381,351
Ensembl chr 4:66,371,511...66,380,734
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein CTD PMID:28444915 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt13 keratin 13 decreases expression ISO hydroquinone results in decreased expression of KRT13 mRNA CTD PMID:31256213 NCBI chr10:88,032,130...88,036,040
Ensembl chr10:88,032,130...88,036,040
JBrowse link
G Krt19 keratin 19 decreases expression ISO hydroquinone results in decreased expression of KRT19 mRNA CTD PMID:31256213 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt23 keratin 23 increases expression ISO hydroquinone results in increased expression of KRT23 mRNA CTD PMID:31256213 NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
JBrowse link
G Krt24 keratin 24 decreases expression ISO hydroquinone results in decreased expression of KRT24 mRNA CTD PMID:31256213 NCBI chr10:87,190,184...87,195,075
Ensembl chr10:87,189,934...87,195,075
JBrowse link
G Krt78 keratin 78 increases expression ISO hydroquinone results in increased expression of KRT78 mRNA CTD PMID:31256213 NCBI chr 7:143,545,245...143,553,063
Ensembl chr 7:143,545,411...143,552,588
JBrowse link
G Krt80 keratin 80 increases expression ISO hydroquinone results in increased expression of KRT80 mRNA CTD PMID:31256213 NCBI chr 7:142,995,715...143,015,932
Ensembl chr 7:142,994,119...143,016,040
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression
multiple interactions
ISO hydroquinone results in increased expression of LAMA4 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]
CTD PMID:18055817 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lasp1 LIM and SH3 protein 1 affects expression ISO hydroquinone affects the expression of LASP1 protein CTD PMID:20021034 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO hydroquinone results in increased expression of LCN2 mRNA CTD PMID:31256213 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]
hydroquinone results in decreased expression of LEF1 protein
CTD PMID:28886972 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lgalsl galectin-like increases expression ISO hydroquinone results in increased expression of LGALSL mRNA CTD PMID:31256213 NCBI chr14:105,047,915...105,055,421
Ensembl chr14:105,047,919...105,055,421
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression ISO hydroquinone results in decreased expression of LGR4 mRNA CTD PMID:31256213 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lipg lipase G, endothelial type increases expression ISO hydroquinone results in increased expression of LIPG mRNA CTD PMID:31256213 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lmna lamin A/C affects expression ISO hydroquinone affects the expression of LMNA protein CTD PMID:17181942 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC102548682 histone H4-like decreases expression ISO hydroquinone results in decreased expression of H4C6 mRNA CTD PMID:23416264 NCBI chr17:43,616,218...43,673,659
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
JBrowse link
G LOC102550598 small proline-rich protein 2I-like increases expression ISO hydroquinone results in increased expression of SPRR2G mRNA CTD PMID:31256213 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G LOC102551184 histone H4-like decreases expression ISO hydroquinone results in decreased expression of H4C12 mRNA CTD PMID:23416264 NCBI chr17:43,770,198...43,821,579 JBrowse link
G LOC290595 hypothetical gene supported by AF152002 decreases expression ISO hydroquinone results in decreased expression of C10ORF99 mRNA CTD PMID:31256213 NCBI chr16:14,352,998...14,360,604
Ensembl chr16:14,353,459...14,360,555
JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression ISO hydroquinone results in increased expression of LORICRIN mRNA CTD PMID:31256213 NCBI chr 2:191,984,455...191,990,713
Ensembl chr 2:191,984,773...191,986,170
JBrowse link
G Lrrc27 leucine rich repeat containing 27 decreases expression ISO hydroquinone results in decreased expression of LRRC27 mRNA CTD PMID:31256213 NCBI chr 1:211,543,751...211,575,823
Ensembl chr 1:211,543,751...211,575,820
JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO hydroquinone results in decreased expression of LRRIQ3 mRNA CTD PMID:31256213 NCBI chr 2:261,403,040...261,499,893
Ensembl chr 2:261,402,980...261,499,891
JBrowse link
G Lss lanosterol synthase decreases expression ISO hydroquinone results in decreased expression of LSS mRNA CTD PMID:31256213 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO hydroquinone results in decreased expression of LY6E mRNA CTD PMID:31256213 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO hydroquinone results in increased expression of LY96 mRNA CTD PMID:31256213 NCBI chr 5:1,972,212...1,989,448 JBrowse link
G Lypd5 Ly6/Plaur domain containing 5 increases expression ISO hydroquinone results in increased expression of LYPD5 mRNA CTD PMID:31256213 NCBI chr 1:81,202,832...81,213,928
Ensembl chr 1:81,208,212...81,213,937
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO hydroquinone results in increased expression of MAFF mRNA CTD PMID:31256213 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr 4:125,684,816...126,300,013
Ensembl chr 4:125,687,307...125,958,112
JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO hydroquinone results in increased expression of MAP1B mRNA CTD PMID:31256213 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MAP7D2 mRNA CTD PMID:31256213 NCBI chr  X:38,400,578...38,467,825
Ensembl chr  X:38,397,261...38,468,360
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:15129224 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:15129224 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 increases expression ISO hydroquinone results in increased expression of MARCHF3 mRNA CTD PMID:31256213 NCBI chr18:51,844,980...51,998,017
Ensembl chr18:51,844,976...52,017,734
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression
multiple interactions
increases expression
ISO hydroquinone results in decreased expression of MBD2 mRNA
PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]
CTD PMID:22245671 PMID:30448557 NCBI chr18:65,814,026...65,885,115
Ensembl chr18:65,814,026...65,885,114
JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 decreases expression ISO hydroquinone results in decreased expression of MBNL3 mRNA CTD PMID:31256213 NCBI chr  X:138,378,674...138,473,365
Ensembl chr  X:138,384,912...138,435,391
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO hydroquinone results in increased expression of MBOAT2 mRNA CTD PMID:31256213 NCBI chr 6:44,009,872...44,135,501
Ensembl chr 6:44,009,872...44,131,387
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO hydroquinone results in increased expression of MCTP1 mRNA CTD PMID:31256213 NCBI chr 2:3,400,883...4,089,949
Ensembl chr 2:3,400,977...4,088,989
JBrowse link
G Mctp2 multiple C2 and transmembrane domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MCTP2 mRNA CTD PMID:31256213 NCBI chr 1:133,324,881...133,559,644
Ensembl chr 1:133,324,301...133,559,975
JBrowse link
G Mettl21a methyltransferase like 21A decreases expression ISO hydroquinone results in decreased expression of METTL21A mRNA CTD PMID:31256213 NCBI chr 9:71,304,138...71,314,015
Ensembl chr 9:71,304,427...71,313,940
JBrowse link
G Mettl7a methyltransferase like 7A decreases expression ISO hydroquinone results in decreased expression of METTL7A mRNA CTD PMID:31256213 NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432
JBrowse link
G MGC105649 hypothetical LOC302884 increases expression ISO hydroquinone results in increased expression of C15ORF48 mRNA CTD PMID:31256213 NCBI chr 3:114,772,603...114,776,156
Ensembl chr 3:114,772,603...114,776,155
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO hydroquinone results in increased expression of MGST1 mRNA CTD PMID:15452088 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mid1 midline 1 decreases expression ISO hydroquinone results in decreased expression of MID1 mRNA CTD PMID:31256213 NCBI chr  X:25,458,782...25,839,941
Ensembl chr  X:25,458,771...25,628,272
JBrowse link
G Mir155 microRNA 155 multiple interactions
increases expression
ISO Doxorubicin promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; trichostatin A promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA] CTD PMID:30448557 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir486 microRNA 486 multiple interactions ISO hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; hydroquinone inhibits the reaction [Hemin results in increased expression of MIR486-1 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055 Ensembl chr16:73,680,363...73,680,490 JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO hydroquinone results in increased expression of MMP1 mRNA CTD PMID:31256213 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] CTD PMID:18055817 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression ISO hydroquinone affects the expression of MMP15 mRNA CTD PMID:15452088 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
ISO hydroquinone results in decreased activity of MMP2 protein
[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]
CTD PMID:16936130 PMID:18055817 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 affects expression
increases expression
ISO hydroquinone affects the expression of MMP3 mRNA
hydroquinone results in increased expression of MMP3 mRNA
CTD PMID:15452088 PMID:31256213 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases secretion
ISO hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]
hydroquinone results in increased expression of MMP9 mRNA
CTD PMID:17669387 PMID:26807887 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mob3b MOB kinase activator 3B decreases expression ISO hydroquinone results in decreased expression of MOB3B mRNA CTD PMID:31256213 NCBI chr 5:50,437,444...50,638,136
Ensembl chr 5:50,438,576...50,638,136
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor multiple interactions
decreases methylation
increases expression
ISO decitabine promotes the reaction [hydroquinone results in increased expression of MPL mRNA]
hydroquinone results in decreased methylation of MPL gene
CTD PMID:22245671 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases chemical synthesis
increases oxidation
ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein; [[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone; [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]; [MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone; [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
MPO protein results in increased chemical synthesis of hydroquinone
MPO protein results in increased oxidation of hydroquinone
CTD PMID:1666626 PMID:10994872 PMID:15777082 PMID:15935818 PMID:31248982 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpzl3 myelin protein zero-like 3 increases expression ISO hydroquinone results in increased expression of MPZL3 mRNA CTD PMID:31256213 NCBI chr 8:49,354,257...49,374,444
Ensembl chr 8:49,354,115...49,376,687
JBrowse link
G Mt1 metallothionein 1 increases expression ISO hydroquinone results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 decreases expression ISO hydroquinone results in decreased expression of MTHFD1 mRNA CTD PMID:31256213 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression ISO hydroquinone results in decreased expression of MTUS1 mRNA CTD PMID:31256213 NCBI chr16:54,240,892...54,386,131
Ensembl chr16:54,291,251...54,386,129
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO hydroquinone results in decreased expression of MX1 mRNA CTD PMID:31256213 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein] CTD PMID:12749906 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO hydroquinone results in decreased expression of MYCL mRNA CTD PMID:31256213 NCBI chr 5:140,691,947...140,698,837
Ensembl chr 5:140,692,779...140,698,609
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO hydroquinone results in decreased expression of MYLIP mRNA CTD PMID:31256213 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Myo1f myosin IF decreases expression ISO hydroquinone results in decreased expression of MYO1F mRNA CTD PMID:31256213 NCBI chr 7:18,440,742...18,491,448
Ensembl chr 7:18,440,742...18,491,448
JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 decreases expression ISO hydroquinone results in decreased expression of N4BP2L1 mRNA CTD PMID:31256213 NCBI chr12:546,759...576,744
Ensembl chr12:546,760...576,746
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO hydroquinone results in increased expression of NCF2 mRNA CTD PMID:31256213 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression ISO hydroquinone results in decreased expression of NEDD4L mRNA CTD PMID:31256213 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nefh neurofilament heavy decreases expression ISO hydroquinone results in decreased expression of NEFH mRNA CTD PMID:31256213 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:164,803,574...164,814,777
Ensembl chr 1:164,803,574...164,814,651
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases expression ISO hydroquinone results in increased expression of NFATC2 mRNA CTD PMID:31256213 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO hydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein] CTD PMID:21059386 PMID:21643505 PMID:28645578 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
hydroquinone results in increased expression of NFKB1 protein
CTD PMID:15894107 PMID:30448557 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:20054000 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta decreases degradation ISO hydroquinone results in decreased degradation of NFKBIB protein CTD PMID:15894107 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO hydroquinone results in increased expression of NIBAN1 mRNA CTD PMID:31256213 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Nid1 nidogen 1 decreases expression ISO hydroquinone results in decreased expression of NID1 mRNA CTD PMID:31256213 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nipal3 NIPA-like domain containing 3 decreases expression ISO hydroquinone results in decreased expression of NIPAL3 mRNA CTD PMID:31256213 NCBI chr 5:153,808,169...153,843,961
Ensembl chr 5:153,807,955...153,840,178
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
hydroquinone results in decreased expression of NOS2 mRNA; hydroquinone results in decreased expression of NOS2 protein
CTD PMID:15831208 PMID:17464197 PMID:19148301 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
decreases response to substance
multiple interactions
ISO hydroquinone results in increased expression of NQO1 mRNA; hydroquinone results in increased expression of NQO1 protein
NQO1 protein results in decreased susceptibility to hydroquinone
ferric chloride promotes the reaction [hydroquinone results in increased expression of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]
CTD PMID:8652659 PMID:10368308 PMID:10393963 PMID:19525446 PMID:21059386 PMID:28645578 PMID:29508652 PMID:30547568 PMID:31256213 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO hydroquinone results in decreased expression of NR4A2 mRNA CTD PMID:31256213 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO hydroquinone results in decreased expression of NRAS mRNA CTD PMID:26047893 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Nudt16 nudix hydrolase 16 decreases expression ISO hydroquinone results in decreased expression of NUDT16 mRNA CTD PMID:31256213 NCBI chr 8:113,673,069...113,675,124
Ensembl chr 8:113,672,758...113,675,128
JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 increases expression ISO hydroquinone results in increased expression of NWD2 mRNA CTD PMID:31256213 NCBI chr14:46,136,780...46,153,320
Ensembl chr14:46,136,786...46,153,212
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO hydroquinone results in decreased expression of OAS1 mRNA CTD PMID:31256213 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO hydroquinone results in decreased expression of OAS2 mRNA CTD PMID:31256213 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO hydroquinone results in increased expression of OASL mRNA CTD PMID:31256213 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Ocln occludin multiple interactions EXP hydroquinone results in decreased degradation of and results in increased expression of OCLN protein CTD PMID:27587462 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Olah oleoyl-ACP hydrolase increases expression ISO hydroquinone results in increased expression of OLAH mRNA CTD PMID:31256213 NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967
JBrowse link
G Olr1356 olfactory receptor 1356 decreases expression ISO hydroquinone results in decreased expression of OR2C1 mRNA CTD PMID:31256213 NCBI chr10:11,941,947...11,942,885
Ensembl chr10:11,941,947...11,942,885
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 increases expression ISO hydroquinone results in increased expression of OVOL1 mRNA CTD PMID:31256213 NCBI chr 1:220,927,309...220,938,814
Ensembl chr 1:220,925,605...220,938,814
JBrowse link
G P2rx4 purinergic receptor P2X 4 increases expression ISO hydroquinone results in increased expression of P2RX4 mRNA CTD PMID:31256213 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Pa2g4 proliferation-associated 2G4 affects expression ISO hydroquinone affects the expression of PA2G4 protein CTD PMID:17181942 NCBI chr 7:2,979,587...2,987,055
Ensembl chr 7:2,979,588...2,987,055
JBrowse link
G Pabpc4l poly(A) binding protein, cytoplasmic 4-like decreases expression ISO hydroquinone results in decreased expression of PABPC4L mRNA CTD PMID:31256213 NCBI chr 2:130,656,212...130,658,202
Ensembl chr 2:130,656,212...130,658,202
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO hydroquinone results in decreased expression of PAICS mRNA CTD PMID:31256213 NCBI chr14:33,563,884...33,580,944
Ensembl chr14:33,563,886...33,580,566
JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B decreases expression ISO hydroquinone results in decreased expression of PAIP2B mRNA CTD PMID:31256213 NCBI chr 4:115,484,676...115,516,307
Ensembl chr 4:115,487,313...115,516,296
JBrowse link
G Palmd palmdelphin decreases expression ISO hydroquinone results in decreased expression of PALMD mRNA CTD PMID:31256213 NCBI chr 2:220,481,292...220,536,004
Ensembl chr 2:220,481,616...220,535,751
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
affects response to substance
increases expression
increases response to substance
affects expression
multiple interactions
ISO hydroquinone results in increased cleavage of PARP1 protein
PARP1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of PARP1 protein
PARP1 protein results in increased susceptibility to hydroquinone
hydroquinone affects the expression of PARP1 protein
3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; hydroquinone results in increased expression of and results in increased cleavage of PARP1 protein; Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]
CTD PMID:19064679 PMID:26047893 PMID:28263894 PMID:28444915 PMID:28886972 PMID:29421518 PMID:30448557 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 decreases expression ISO hydroquinone results in decreased expression of PARP9 mRNA CTD PMID:31256213 NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO hydroquinone results in decreased expression of PBX1 mRNA CTD PMID:31256213 NCBI chr13:86,390,741...86,671,460
Ensembl chr13:86,390,741...86,451,002
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO hydroquinone results in increased expression of PCK2 mRNA CTD PMID:31256213 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO hydroquinone results in decreased expression of PDCD4 mRNA CTD PMID:31256213 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pde11a phosphodiesterase 11A decreases expression ISO hydroquinone results in decreased expression of PDE11A mRNA CTD PMID:31256213 NCBI chr 3:62,818,502...63,211,843
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression ISO hydroquinone results in decreased expression of PDE4B mRNA CTD PMID:31256213 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of PDGFRB mRNA CTD PMID:32198055 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases activity ISO hydroquinone metabolite results in decreased activity of PDPK1 protein; hydroquinone results in decreased activity of PDPK1 protein CTD PMID:20054000 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression ISO hydroquinone results in increased expression of PECAM1 protein CTD PMID:21664406 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO hydroquinone results in decreased expression of PEG3 mRNA CTD PMID:31256213 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pgls 6-phosphogluconolactonase affects expression ISO hydroquinone affects the expression of PGLS protein CTD PMID:17181942 NCBI chr16:20,020,444...20,025,930
Ensembl chr16:20,020,444...20,025,930
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 increases expression ISO hydroquinone results in increased expression of PGLYRP4 mRNA CTD PMID:31256213 NCBI chr 2:190,125,655...190,204,230
Ensembl chr 2:190,125,693...190,148,265
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO hydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:31256213 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression ISO hydroquinone results in decreased expression of PIK3C3 mRNA CTD PMID:31256213 NCBI chr18:22,964,121...23,047,896
Ensembl chr18:22,964,210...23,047,895
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 decreases expression ISO hydroquinone results in decreased expression of PIK3IP1 mRNA CTD PMID:31256213 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein] CTD PMID:28836394 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO hydroquinone results in increased expression of PIM1 mRNA CTD PMID:31256213 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO hydroquinone results in decreased expression of PITX2 mRNA CTD PMID:31256213 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha decreases expression ISO hydroquinone results in decreased expression of PKIA mRNA CTD PMID:31256213 NCBI chr 2:96,593,185...96,668,222
Ensembl chr 2:96,595,088...96,668,222
JBrowse link
G Pkp2 plakophilin 2 increases expression ISO hydroquinone results in increased expression of PKP2 mRNA CTD PMID:31256213 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 increases expression ISO hydroquinone results in increased expression of PLCXD1 mRNA CTD PMID:31256213 NCBI chr12:52,640,939...52,645,153
Ensembl chr12:52,641,222...52,676,608
JBrowse link
G Pld1 phospholipase D1 decreases expression ISO hydroquinone results in decreased expression of PLD1 mRNA CTD PMID:31256213 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Pllp plasmolipin decreases expression ISO hydroquinone results in decreased expression of PLLP mRNA CTD PMID:31256213 NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641
JBrowse link
G Pmfbp1 polyamine modulated factor 1 binding protein 1 increases expression ISO hydroquinone results in increased expression of PMFBP1 mRNA CTD PMID:31256213 NCBI chr19:42,132,551...42,196,990
Ensembl chr19:42,132,527...42,180,981
JBrowse link
G Polh DNA polymerase eta increases response to substance
multiple interactions
ISO POLH mutant form results in increased susceptibility to hydroquinone
[POLH mutant form results in increased susceptibility to hydroquinone] which results in increased expression of H2AX protein
CTD PMID:22981619 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO hydroquinone results in decreased expression of POLR1B mRNA CTD PMID:31256213 NCBI chr 3:121,632,043...121,656,506
Ensembl chr 3:121,632,043...121,656,506
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO hydroquinone results in increased expression of PPARD mRNA CTD PMID:31256213 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO hydroquinone results in increased expression of PPM1D mRNA CTD PMID:23416264 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO hydroquinone results in increased expression of PPP1R15A mRNA CTD PMID:31256213 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions ISO PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha multiple interactions ISO PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr13:110,033,550...110,077,946
Ensembl chr13:110,033,550...110,077,946
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 decreases expression ISO hydroquinone results in decreased expression of PPTC7 mRNA CTD PMID:31256213 NCBI chr12:39,731,107...39,769,480
Ensembl chr12:39,731,121...39,769,480
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO hydroquinone results in increased expression of PRDM1 mRNA CTD PMID:31256213 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO hydroquinone results in increased expression of PRDX1 mRNA CTD PMID:15452088 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO hydroquinone results in increased expression of PRKDC mRNA; hydroquinone results in increased expression of PRKDC protein CTD PMID:20036648 PMID:23940708 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Prr9 proline rich 9 increases expression ISO hydroquinone results in increased expression of PRR9 mRNA CTD PMID:31256213 NCBI chr 2:192,025,457...192,036,073
Ensembl chr 2:192,025,875...192,027,225
JBrowse link
G Prss3 serine protease 3 increases expression ISO hydroquinone results in increased expression of PRSS3 mRNA CTD PMID:31256213 NCBI chr 4:70,614,524...70,617,998
Ensembl chr 4:70,614,524...70,617,998
JBrowse link
G Psapl1 prosaposin-like 1 increases expression ISO hydroquinone results in increased expression of PSAPL1 mRNA CTD PMID:31256213 NCBI chr14:79,711,694...79,714,254
Ensembl chr14:79,711,694...79,714,254
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 decreases expression ISO hydroquinone results in decreased expression of PSRC1 mRNA CTD PMID:23416264 NCBI chr 2:211,176,437...211,181,078
Ensembl chr 2:211,176,556...211,181,123
JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression ISO hydroquinone results in decreased expression of PTGR2 mRNA CTD PMID:31256213 NCBI chr 6:107,999,832...108,031,645
Ensembl chr 6:107,999,846...108,031,643
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO hydroquinone results in increased expression of PTGS2 mRNA CTD PMID:31256213 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein CTD PMID:31248982 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Pygb glycogen phosphorylase B increases expression ISO hydroquinone results in increased expression of PYGB mRNA CTD PMID:31256213 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression ISO hydroquinone results in increased expression of QPCT mRNA CTD PMID:31256213 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559
JBrowse link
G Rab30 RAB30, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB30 mRNA CTD PMID:31256213 NCBI chr 1:157,573,344...157,667,973
Ensembl chr 1:157,573,324...157,660,008
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO hydroquinone results in increased expression of RAB3B mRNA CTD PMID:31256213 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rab7b Rab7b, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB7B mRNA CTD PMID:31256213 NCBI chr13:48,456,143...48,483,714
Ensembl chr13:48,455,923...48,482,138
JBrowse link
G Rabgap1l RAB GTPase activating protein 1-like decreases expression ISO hydroquinone results in decreased expression of RABGAP1L mRNA CTD PMID:31256213 NCBI chr13:77,975,392...78,609,009
Ensembl chr13:78,011,047...78,609,045
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAP1A protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein] CTD PMID:32198055 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein; hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of RB protein
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form
CTD PMID:26047893 PMID:30506647 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 increases expression ISO hydroquinone results in increased expression of RBCK1 mRNA CTD PMID:31256213 NCBI chr 3:147,793,014...147,809,941
Ensembl chr 3:147,793,017...147,809,919
JBrowse link
G Rdh12 retinol dehydrogenase 12 increases expression ISO hydroquinone results in increased expression of RDH12 mRNA CTD PMID:31256213 NCBI chr 6:102,392,828...102,405,750
Ensembl chr 6:102,392,828...102,405,750
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs decreases expression ISO hydroquinone results in decreased expression of RECK mRNA CTD PMID:31256213 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Recql4 RecQ like helicase 4 increases expression ISO hydroquinone results in increased expression of RECQL4 mRNA CTD PMID:15452088 NCBI chr 7:117,765,892...117,773,128
Ensembl chr 7:117,763,783...117,773,134
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]
hydroquinone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
CTD PMID:15894107 PMID:16928326 PMID:20054000 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Reps1 RALBP1 associated Eps domain containing 1 decreases expression ISO hydroquinone results in decreased expression of REPS1 mRNA CTD PMID:31256213 NCBI chr 1:13,262,049...13,298,347
Ensembl chr 1:13,212,324...13,298,347
JBrowse link
G Rftn1 raftlin lipid raft linker 1 increases expression ISO hydroquinone results in increased expression of RFTN1 mRNA CTD PMID:31256213 NCBI chr 9:12,740,885...12,942,358
Ensembl chr 9:12,740,885...12,942,358
JBrowse link
G Rfx5 regulatory factor X5 decreases expression ISO hydroquinone results in decreased expression of RFX5 mRNA CTD PMID:31256213 NCBI chr 2:196,119,054...196,128,109
Ensembl chr 2:196,120,580...196,128,095
JBrowse link
G RGD1306063 similar to HT021 decreases expression ISO hydroquinone results in decreased expression of C3ORF14 mRNA CTD PMID:31256213 NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
JBrowse link
G RGD1309651 similar to 1190005I06Rik protein increases expression ISO hydroquinone results in increased expression of C16ORF74 mRNA CTD PMID:31256213 NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 decreases expression ISO hydroquinone results in decreased expression of H4C14 mRNA CTD PMID:23416264 NCBI chr 4:170,762,862...170,763,962
Ensembl chr 4:170,763,605...170,763,916
JBrowse link
G Rgs17 regulator of G-protein signaling 17 increases expression ISO hydroquinone results in increased expression of RGS17 mRNA CTD PMID:31256213 NCBI chr 1:42,491,566...42,587,735
Ensembl chr 1:42,492,761...42,587,721
JBrowse link
G Rhcg Rh family, C glycoprotein increases expression ISO hydroquinone results in increased expression of RHCG mRNA CTD PMID:31256213 NCBI chr 1:141,325,854...141,349,881
Ensembl chr 1:141,325,856...141,349,881
JBrowse link
G Riok2 RIO kinase 2 decreases expression ISO hydroquinone results in decreased expression of RIOK2 mRNA CTD PMID:31256213 NCBI chr 1:59,130,008...59,146,457
Ensembl chr 1:59,129,951...59,146,776
JBrowse link
G Rnase4 ribonuclease A family member 4 decreases expression ISO hydroquinone results in decreased expression of RNASE4 mRNA CTD PMID:31256213 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rnasel ribonuclease L decreases expression ISO hydroquinone results in decreased expression of RNASEL mRNA CTD PMID:31256213 NCBI chr13:71,188,712...71,202,636
Ensembl chr13:71,192,142...71,202,625
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO hydroquinone results in decreased expression of ROR1 mRNA CTD PMID:31256213 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 increases expression ISO hydroquinone results in increased expression of RPS6KA2 mRNA CTD PMID:31256213 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rptn repetin increases expression ISO hydroquinone results in increased expression of RPTN mRNA CTD PMID:31256213 NCBI chr 2:193,722,394...193,729,040
Ensembl chr 2:193,724,248...193,728,302
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO hydroquinone results in increased expression of RRAD mRNA CTD PMID:31256213 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Rrp12 ribosomal RNA processing 12 homolog decreases expression ISO hydroquinone results in decreased expression of RRP12 mRNA CTD PMID:31256213 NCBI chr 1:261,106,768...261,140,416
Ensembl chr 1:261,106,760...261,140,389
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO hydroquinone results in increased expression of RUNX2 mRNA CTD PMID:22960397 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO hydroquinone results in decreased expression of SATB1 mRNA CTD PMID:31256213 NCBI chr 9:2,181,135...2,277,949
Ensembl chr 9:2,190,915...2,274,629
JBrowse link
G Sbk1 SH3 domain binding kinase 1 decreases expression ISO hydroquinone results in decreased expression of SBK1 mRNA CTD PMID:31256213 NCBI chr 1:197,636,230...197,681,031
Ensembl chr 1:67,368,384...67,390,141
Ensembl chr 1:67,368,384...67,390,141
JBrowse link
G Scara3 scavenger receptor class A, member 3 decreases expression ISO hydroquinone results in decreased expression of SCARA3 mRNA CTD PMID:31256213 NCBI chr15:42,605,505...42,638,409
Ensembl chr15:42,605,473...42,638,392
JBrowse link
G Scfd2 sec1 family domain containing 2 decreases expression ISO hydroquinone results in decreased expression of SCFD2 mRNA CTD PMID:31256213 NCBI chr14:36,216,002...36,543,661
Ensembl chr14:36,216,002...36,543,658