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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroquinones
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Accession:CHEBI:24646 term browser browse the term
Definition:Benzenediols that have the hydroxy substituents in the 1- and 4-positions.
Synonyms:related_synonym: 1,4-benzoquinols;   Formula=C6H2O2R4;   SMILES=OC1=C(*)C(*)=C(O)C(*)=C1*;   a 1,4-benzoquinol;   a quinol;   benzene-1,4-diols
 alt_id: CHEBI:134188;   MESH:D006873
 xref_mesh: MESH:D006873



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hydroquinones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases response to substance ISO NFE2L2 protein results in decreased susceptibility to Hydroquinones CTD PMID:20932822 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
1,4-dihydroxy-2-naphthoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:27837168 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of GPR35 protein CTD PMID:20826425 NCBI chr 9:93,526,691...93,539,302
Ensembl chr 9:93,527,127...93,539,299
JBrowse link
2,5-di-tert-butylbenzene-1,4-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 2,5-di-tert-butylhydroquinone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 2,5-di-tert-butylhydroquinone results in increased expression of GSTP1 protein CTD PMID:12680784 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases response to substance ISO NFE2L2 gene mutant form results in increased susceptibility to 2,5-di-tert-butylhydroquinone CTD PMID:12842875 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,5-di-tert-butylhydroquinone binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 2,5-di-tert-butylhydroquinone binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
2,5-dihydroxycinnamic acid methyl ester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 multiple interactions ISO CSF2 protein affects the susceptibility to [Nitroblue Tetrazolium co-treated with methyl 2,5-dihydroxycinnamate] CTD PMID:8471626 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
2-tert-butylhydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of ABCC1 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCC1 protein CTD PMID:11836020 PMID:16014739 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO
EXP
2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCC2 protein CTD PMID:11264000 PMID:11836020 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of ABCG2 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCG2 protein
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]
CTD PMID:17077187 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO 2-tert-butylhydroquinone results in increased expression of ADH7 mRNA CTD PMID:16014739 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO
EXP
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]; AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]
2-tert-butylhydroquinone results in increased activity of and results in increased localization of AHR protein
CTD PMID:12948865 PMID:15608132 PMID:17077187 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 2-tert-butylhydroquinone results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of AKR1C1 mRNA CTD PMID:9973208 PMID:30806763 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of AKR1C1 mRNA CTD PMID:9973208 PMID:30806763 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein] CTD PMID:23112101 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ar androgen receptor multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2-tert-butylhydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of ATP5F1A protein] CTD PMID:31726083 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Bach1 BTB domain and CNC homolog 1 affects localization
multiple interactions
ISO 2-tert-butylhydroquinone affects the localization of BACH1 protein
2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; [ferric chloride results in increased oxidation of 2-tert-butylhydroquinone] promotes the reaction [2-tert-butylhydroquinone analog binds to BACH1 protein]
CTD PMID:28645578 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in decreased expression of BAX protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of BAX mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of BAX protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
[2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in decreased expression of BAX protein
CTD PMID:22275372 PMID:26878773 PMID:28583816 PMID:32565124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to BCL2 promoter]; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in increased expression of BCL2 protein; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of BCL2 mRNA]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of BCL2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in decreased expression of BCL2 protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
2-tert-butylhydroquinone results in increased expression of BCL2 mRNA; 2-tert-butylhydroquinone results in increased expression of BCL2 protein
CTD PMID:22275372 PMID:26878773 PMID:28583816 PMID:32565124 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bco2 beta-carotene oxygenase 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of BCO2 mRNA CTD PMID:16014739 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 2-tert-butylhydroquinone results in increased expression of BLVRB mRNA CTD PMID:16014739 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of CASP3 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased cleavage of CASP3 protein]
2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]
CTD PMID:22275372 PMID:25341683 PMID:25645596 PMID:26878773 PMID:28583816 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP4 protein] CTD PMID:25341683 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein] CTD PMID:22275372 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Cat catalase multiple interactions
increases activity
ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
2-tert-butylhydroquinone results in increased activity of CAT protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CAT mRNA]
CTD PMID:26878773 PMID:32428544 PMID:32565124 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CBR3 mRNA CTD PMID:16014739 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion ISO 2-tert-butylhydroquinone results in increased secretion of CCL5 protein CTD PMID:30806763 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of CCN2 mRNA CTD PMID:16014739 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of CCND1 protein
2-tert-butylhydroquinone promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]
CTD PMID:26878773 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd5l Cd5 molecule-like increases expression ISO 2-tert-butylhydroquinone results in increased expression of CD5L mRNA CTD PMID:16014739 NCBI chr 2:172,791,007...172,802,018 JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein] CTD PMID:30171972 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cd86 CD86 molecule increases expression ISO 2-tert-butylhydroquinone results in increased expression of CD86 protein CTD PMID:19033392 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein]
2-tert-butylhydroquinone results in increased expression of CDK4 protein
CTD PMID:26878773 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression
ISO 2-tert-butylhydroquinone results in increased expression of and results in increased activity of CES1 protein alternative form; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form] CTD PMID:19715681 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Crebbp CREB binding protein multiple interactions ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; 2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]] CTD PMID:21443188 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 affects response to substance ISO CREG2 gene SNP affects the susceptibility to 2-tert-butylhydroquinone CTD PMID:25622337 NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein]; 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein]; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CSF1R protein CTD PMID:23112101 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Ctsk cathepsin K multiple interactions ISO [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein CTD PMID:23112101 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cul3 cullin 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein] CTD PMID:18417180 PMID:30261176 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL1 mRNA CTD PMID:30806763 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL1 mRNA CTD PMID:30806763 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb5a cytochrome b5 type A increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYB5A mRNA CTD PMID:16014739 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of CYBB protein] CTD PMID:28844481 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CYP11A1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CYP11A1 protein] CTD PMID:32565124 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO 2-tert-butylhydroquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; 2-tert-butylhydroquinone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-tert-butylhydroquinone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; FH535 inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased activity of CYP1A1 protein]; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP1A1 mRNA]
2-tert-butylhydroquinone results in increased expression of and results in increased activity of CYP1A1 protein; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased activity of CYP1A1 protein]
CTD PMID:9973208 PMID:15608132 PMID:15627257 PMID:16581943 PMID:25174530 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYP2A5 mRNA CTD PMID:29788535 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYP2C19 mRNA; 2-tert-butylhydroquinone results in increased expression of CYP2C19 protein CTD PMID:24830941 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein] CTD PMID:25341683 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dsc3 desmocollin 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of DSC3 mRNA CTD PMID:16014739 NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions
EXP
ISO
2-tert-butylhydroquinone results in increased expression of EPHX1 mRNA
NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon]
2-tert-butylhydroquinone results in increased expression of EPHX1 exon; 2-tert-butylhydroquinone results in increased expression of EPHX1 protein alternative form
CTD PMID:20650352 PMID:24704207 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Esd esterase D increases expression ISO 2-tert-butylhydroquinone results in increased expression of ESD mRNA CTD PMID:16014739 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions EXP 2-tert-butylhydroquinone promotes the reaction [FGF1 protein results in increased abundance of and results in increased secretion of Glutathione]; FGF1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein] CTD PMID:16524372 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf18 fibroblast growth factor 18 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of FGF18 mRNA CTD PMID:16014739 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased expression of FOS protein
2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of FOS protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FOS protein]; 2-tert-butylhydroquinone promotes the reaction [FOS protein binds to CYP2C9 promoter]
CTD PMID:24830941 PMID:28844481 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of FSHB protein] CTD PMID:32565124 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA]; PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA]; wortmannin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] CTD PMID:23829535 PMID:25003661 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of FTL1 mRNA CTD PMID:16014739 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Ftmt ferritin mitochondrial increases expression ISO 2-tert-butylhydroquinone results in increased expression of FTMT mRNA CTD PMID:15664434 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha affects localization ISO 2-tert-butylhydroquinone affects the localization of GABPA protein CTD PMID:16308312 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Gata3 GATA binding protein 3 increases activity ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein CTD PMID:22250088 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression
increases expression
multiple interactions
increases activity
ISO
EXP
2-tert-butylhydroquinone affects the expression of GCLC mRNA
2-tert-butylhydroquinone results in increased expression of GCLC mRNA
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of GCLC mRNA]; [2-tert-butylhydroquinone results in increased activity of GCLC protein] which results in increased abundance of Glutathione; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]
CTD PMID:7955076 PMID:10978506 PMID:12007577 PMID:15946948 PMID:16014739 More... NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression
ISO
EXP
NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA]
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; [2,2',4,4'-tetrabromodiphenyl ether co-treated with 2-tert-butylhydroquinone] results in increased expression of GCLM mRNA
CTD PMID:10978506 PMID:12007577 PMID:12081989 PMID:16014739 PMID:19183254 More... NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO 2-tert-butylhydroquinone results in increased expression of GPR87 mRNA CTD PMID:16014739 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
EXP 2-tert-butylhydroquinone results in increased expression of GPX1 protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of GPX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of GPX1 protein]
CTD PMID:28583816 PMID:32565124 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of GRIA1 mRNA CTD PMID:16014739 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased activity of GSR protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD PMID:12572858 PMID:24970285 PMID:32565124 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased expression of GSS mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSS mRNA
CTD PMID:10978506 PMID:19183254 PMID:32428544 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
EXP 2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA; 2-tert-butylhydroquinone results in increased expression of GSTA2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2]; 2-tert-butylhydroquinone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of GSTA2 protein; [S-Nitroso-N-Acetylpenicillamine co-treated with 2-tert-butylhydroquinone] results in increased expression of GSTA2; Dexamethasone promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of GSTA2 protein]; Dexamethasone promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA]; N-acetylsphingosine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 protein]
CTD PMID:7587946 PMID:12242683 PMID:15155840 PMID:15319326 PMID:15357004 More... NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression
multiple interactions
increases activity
EXP
ISO
2-tert-butylhydroquinone results in increased expression of GSTA5 mRNA
2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA
Tetradecanoylphorbol Acetate promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA]
2-tert-butylhydroquinone results in increased activity of GSTA1 protein
CTD PMID:7568053 PMID:15627257 PMID:16014739 PMID:20650352 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of GSTM1 protein
2-tert-butylhydroquinone results in increased expression of GSTM1 mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSTM1 mRNA
CTD PMID:21443188 PMID:32428544 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP
ISO
2-tert-butylhydroquinone results in increased expression of GSTP1 protein
2-tert-butylhydroquinone results in increased expression of GSTP1 mRNA
CTD PMID:12680784 PMID:15533597 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gzmb granzyme B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein] CTD PMID:30171972 NCBI chr15:30,343,361...30,346,792 JBrowse link
G H2ax H2A.X variant histone multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of H2AX protein] CTD PMID:28583816 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hbg1 hemoglobin subunit gamma 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of HBG1 mRNA CTD PMID:21464371 NCBI chr 1:158,271,993...158,273,371
Ensembl chr 1:158,271,873...158,273,425
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression EXP 2-tert-butylhydroquinone results in decreased expression of HES1 protein CTD PMID:29663635 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein] CTD PMID:23112101 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; 2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; [2-tert-butylhydroquinone co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA; brusatol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]
2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA; 2-tert-butylhydroquinone results in increased expression of HMOX1 protein
2-tert-butylhydroquinone inhibits the reaction [decamethrin results in increased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [decamethrin results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in increased expression of HMOX1 protein]; [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride; FGF1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; NFE2L2 gene mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of HMOX1 mRNA; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]
CTD PMID:8612205 PMID:10473555 PMID:10874044 PMID:10975858 PMID:16014739 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of HSD17B3 mRNA] CTD PMID:32565124 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of HSD3B1 mRNA] CTD PMID:32565124 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of HSF1 mRNA CTD PMID:30309986 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein] CTD PMID:25341683 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Ifng interferon gamma multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Dinoprostone]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; 2-tert-butylhydroquinone results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of IFNG mRNA; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]] CTD PMID:22250088 PMID:23942037 PMID:30171972 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of IKBKB protein modified form] CTD PMID:28844481 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of IL10 mRNA]
2-tert-butylhydroquinone results in increased expression of IL10 mRNA
CTD PMID:32565124 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12a interleukin 12A multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]] CTD PMID:25680285 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]] CTD PMID:25680285 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL13 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL13 mRNA CTD PMID:22250088 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il16 interleukin 16 increases secretion ISO 2-tert-butylhydroquinone results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il17d interleukin 17D multiple interactions ISO 2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of IL17D protein] CTD PMID:34023435 NCBI chr15:31,665,795...31,688,840 JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 2-tert-butylhydroquinone results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of IL1B protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL1B protein] CTD PMID:28583816 PMID:28844481 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in decreased expression of IL2 mRNA
2-tert-butylhydroquinone results in decreased expression of and results in decreased secretion of IL2 protein
CTD PMID:23945499 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]] CTD PMID:25680285 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in decreased expression of IL2RA mRNA; 2-tert-butylhydroquinone results in decreased expression of IL2RA protein
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]
CTD PMID:23945499 PMID:30171972 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL4 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL4 mRNA
2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of IL4 protein]
CTD PMID:22250088 PMID:34023435 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein CTD PMID:22250088 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased secretion of IL6 protein]; 2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of IL6 protein]
2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL6 protein]
CTD PMID:25305463 PMID:28844481 PMID:34023435 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
ISO 2-tert-butylhydroquinone promotes the reaction [JUND protein binds to CYP2C9 promoter]; 2-tert-butylhydroquinone promotes the reaction [JUND protein modified form binds to CYP2C9 promoter]; JUND mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP2C9 mRNA]; pyrazolanthrone inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of JUND protein] CTD PMID:24830941 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
decreases response to substance
affects binding
ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]
2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in decreased expression of KEAP1 protein]
2-tert-butylhydroquinone results in increased expression of KEAP1 protein
KEAP1 protein mutant form results in decreased susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased activity of NFE2L2 protein; Cadmium Chloride inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]]
2-tert-butylhydroquinone binds to KEAP1 protein
CTD PMID:18417180 PMID:18512965 PMID:19033392 PMID:19808700 PMID:23589329 More... NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of LHB protein] CTD PMID:32565124 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO 2-tert-butylhydroquinone results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of MAPK1 protein]
CTD PMID:24830941 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of MAPK3 protein] CTD PMID:24830941 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of MCHR1 mRNA CTD PMID:16014739 NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032
JBrowse link
G Mfn2 mitofusin 2 multiple interactions
increases expression
EXP 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of MFN2 protein]
2-tert-butylhydroquinone results in increased expression of MFN2 protein
CTD PMID:31726083 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of MT1 mRNA
2-tert-butylhydroquinone promotes the reaction [Cycloheximide results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Zinc deficiency inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]
CTD PMID:14998373 PMID:19276070 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A increases expression ISO 2-tert-butylhydroquinone results in increased expression of MT2 mRNA CTD PMID:14998373 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA] CTD PMID:14998373 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Mtrf1 mitochondrial translation release factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of MTRF1 mRNA CTD PMID:16014739 NCBI chr15:54,776,885...54,804,699
Ensembl chr15:54,776,937...54,804,704
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
increases response to substance
increases expression
increases activity
affects response to substance
decreases response to substance
increases ubiquitination
increases stability
affects binding
ISO
EXP
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]; 2-tert-butylhydroquinone affects the localization of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; 2-tert-butylhydroquinone results in increased expression of and affects the localization of NFE2L2 protein; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone results in increased stability of and affects the localization of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased susceptibility to arsenite; [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein] which results in decreased susceptibility to Oxidopamine; brusatol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; Metformin inhibits the reaction [2-tert-butylhydroquinone results in increased stability of and affects the localization of NFE2L2 protein]; NFE2L2 affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form]
2-tert-butylhydroquinone affects the localization of NFE2L2 protein
NFE2L2 protein mutant form results in increased susceptibility to 2-tert-butylhydroquinone
NFE2L2 protein affects the susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin affects the expression of and affects the localization of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to BCL2 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone results in increased expression of and affects the localization of NFE2L2 protein; [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased activity of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased activity of TBX21 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of IFNG mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL13 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL4 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL13 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL4 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in decreased expression of BAX protein; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in increased expression of BCL2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein]; Cadmium Chloride inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of BCL2 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitrites]]
2-tert-butylhydroquinone results in increased activity of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein
2-tert-butylhydroquinone affects the localization of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 protein]; [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride; [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; decamethrin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; N-acetylsphingosine inhibits the reaction [2-tert-butylhydroquinone results in increased localization of NFE2L2 protein]; NFE2L2 gene mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]
NFE2L2 protein results in decreased susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone results in increased expression of NFE2L2 mRNA; 2-tert-butylhydroquinone results in increased expression of NFE2L2 protein
2-tert-butylhydroquinone binds to NFE2L2 protein
CTD PMID:10473555 PMID:10874044 PMID:12446695 PMID:14510636 PMID:14998373 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased phosphorylation of NFKBIA protein] CTD PMID:28583816 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of NKD1 mRNA CTD PMID:16014739 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 protein] CTD PMID:32073640 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 decreases expression EXP 2-tert-butylhydroquinone results in decreased expression of NOTCH1 protein CTD PMID:29663635 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased activity of NQO1 protein
2-tert-butylhydroquinone results in increased expression of NQO1 mRNA; 2-tert-butylhydroquinone results in increased expression of NQO1 protein
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of NQO1 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; AG-879 inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Paraquat inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Zinc promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NQO1 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NQO1 protein]; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of NQO1 protein; [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 protein; Dexamethasone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NQO1 protein]; Dexamethasone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]; [lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA; [sodium arsenite co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA; [sodium arsenite co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 protein]; NFE2L2 affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA]
CTD PMID:7587946 PMID:9029048 PMID:11163336 PMID:14510636 PMID:14998373 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in decreased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of PCNA protein] CTD PMID:32565124 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO 2-tert-butylhydroquinone results in increased expression of PGD mRNA CTD PMID:16014739 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of PRDX1 mRNA CTD PMID:16014739 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prf1 perforin 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein] CTD PMID:30171972 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression ISO 2-tert-butylhydroquinone results in increased expression of PRKACA mRNA CTD PMID:16014739 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Procr protein C receptor increases expression ISO 2-tert-butylhydroquinone results in increased expression of PROCR mRNA CTD PMID:16014739 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] CTD PMID:23829535 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of PTGR1 mRNA CTD PMID:16014739 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of PTGS2 protein] CTD PMID:28583816 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases expression ISO 2-tert-butylhydroquinone results in increased expression of REL mRNA CTD PMID:16014739 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased activity of RELA protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA protein]
CTD PMID:28583816 PMID:28844481 PMID:32073640 PMID:32565124 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO 2-tert-butylhydroquinone results in increased expression of RORC mRNA CTD PMID:16014739 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC3A2 mRNA CTD PMID:19183254 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC40A1 mRNA CTD PMID:16014739 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC7A11 mRNA CTD PMID:19183254 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of SOD1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in decreased expression of SOD1 protein] CTD PMID:28844481 PMID:32565124 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
ISO 2-tert-butylhydroquinone results in increased expression of SOD2 mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of SOD2 mRNA
CTD PMID:32428544 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sqor sulfide quinone oxidoreductase increases expression ISO 2-tert-butylhydroquinone results in increased expression of SQOR mRNA CTD PMID:16014739 NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
2-tert-butylhydroquinone results in increased expression of SQSTM1 protein
[thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of SQSTM1 protein
CTD PMID:23589329 PMID:31726083 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of SRC protein CTD PMID:23112101 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SRXN1 mRNA CTD PMID:16014739 PMID:22003191 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of STAR mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of STAR protein] CTD PMID:32565124 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased activity of TBX21 protein CTD PMID:22250088 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of TNF protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF protein]
CTD PMID:28583816 PMID:32073640 PMID:32565124 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein]; 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein]; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CSF1R protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of SRC protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of TOB1 mRNA CTD PMID:16014739 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:12949356 PMID:16014739 PMID:30806763 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP 2-tert-butylhydroquinone results in increased expression of UGT1A1 mRNA CTD PMID:20650352 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression
increases activity
multiple interactions
EXP
ISO
2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA
2-tert-butylhydroquinone results in increased activity of UGT1A6 protein
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]
CTD PMID:10220484 PMID:12948865 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO 2-tert-butylhydroquinone results in increased expression of UGT1A9 mRNA CTD PMID:10220484 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases expression ISO 2-tert-butylhydroquinone results in increased expression of UGT2B7 mRNA CTD PMID:10220484 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
6-decylubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone inhibits the reaction [Diclofenac results in increased activity of CASP3 protein] CTD PMID:14599462 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) increases metabolic processing
multiple interactions
EXP DHODH protein results in increased metabolism of 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone
teriflunomide inhibits the reaction [DHODH protein results in increased metabolism of 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone]
CTD PMID:9802339 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
hydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) decreases expression ISO hydroquinone results in decreased expression of A4GALT mRNA CTD PMID:31256213 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO hydroquinone results in increased expression of ABCC3 mRNA CTD PMID:31256213 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO hydroquinone results in decreased expression of ACE2 mRNA CTD PMID:31256213 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression ISO hydroquinone results in increased expression of ADAP2 mRNA CTD PMID:31256213 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO hydroquinone results in increased expression of ADPRH mRNA CTD PMID:31256213 NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein increases expression ISO hydroquinone results in increased expression of ADTRP mRNA CTD PMID:31256213 NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO hydroquinone results in increased expression of AEN mRNA CTD PMID:23416264 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO hydroquinone results in decreased expression of AFAP1 mRNA CTD PMID:31256213 NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263
JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 decreases expression ISO hydroquinone results in decreased expression of AGGF1 mRNA CTD PMID:31256213 NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952
JBrowse link
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
increases expression
ISO
EXP
hydroquinone affects the localization of AHR protein
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]
CTD PMID:15935814 PMID:29935983 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression ISO hydroquinone results in increased expression of AIFM2 mRNA CTD PMID:31256213 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO hydroquinone results in decreased expression of AKR1B10 mRNA CTD PMID:31256213 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17464197 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of hydroquinone CTD PMID:8831264 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO hydroquinone results in increased expression of ALDH1L2 mRNA CTD PMID:31256213 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO hydroquinone results in increased expression of ALDH2 mRNA CTD PMID:15452088 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO hydroquinone results in increased expression of ALDH3A1 mRNA CTD PMID:31256213 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO hydroquinone results in increased expression of ALOX12 mRNA CTD PMID:31256213 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO hydroquinone results in increased expression of ALOX12B mRNA CTD PMID:31256213 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 increases expression ISO hydroquinone results in increased expression of ALOXE3 mRNA CTD PMID:31256213 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328
JBrowse link
G Alpk1 alpha-kinase 1 increases expression ISO hydroquinone results in increased expression of ALPK1 mRNA CTD PMID:31256213 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157
JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO hydroquinone results in decreased expression of ANKDD1A mRNA CTD PMID:31256213 NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651
JBrowse link
G Anxa1 annexin A1 increases expression ISO hydroquinone results in increased expression of ANXA1 mRNA CTD PMID:31256213 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa3 annexin A3 increases expression ISO hydroquinone results in increased expression of ANXA3 mRNA CTD PMID:31256213 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Apoe apolipoprotein E decreases expression
multiple interactions
EXP hydroquinone results in decreased expression of APOE mRNA
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA]
CTD PMID:33188856 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO hydroquinone results in decreased expression of AQP3 mRNA CTD PMID:31256213 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Arg1 arginase 1 increases expression ISO hydroquinone results in increased expression of ARG1 mRNA CTD PMID:31256213 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 increases expression ISO hydroquinone results in increased expression of ARG2 mRNA CTD PMID:31256213 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO hydroquinone results in increased expression of ARHGAP27 mRNA CTD PMID:31256213 NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185
JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO hydroquinone results in decreased expression of ARHGAP42 mRNA CTD PMID:31256213 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha affects expression ISO hydroquinone affects the expression of ARHGDIA protein CTD PMID:17181942 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO hydroquinone results in increased expression of ARHGEF2 mRNA CTD PMID:31256213 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 decreases expression ISO hydroquinone results in decreased expression of ARHGEF26 mRNA CTD PMID:31256213 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression ISO hydroquinone results in decreased expression of ARL3 mRNA CTD PMID:31256213 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO hydroquinone results in increased expression of ASNS mRNA CTD PMID:31256213 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression ISO hydroquinone results in increased expression of ASPRV1 mRNA CTD PMID:31256213 NCBI chr 4:119,076,169...119,078,887
Ensembl chr 4:119,077,356...119,078,379
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO hydroquinone results in increased expression of ATF3 mRNA CTD PMID:31256213 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO hydroquinone results in increased expression of ATF4 mRNA CTD PMID:15452088 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
ISO PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA] CTD PMID:28263894 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 increases expression ISO hydroquinone results in increased expression of ATP2C2 mRNA CTD PMID:31256213 NCBI chr19:47,754,120...47,811,369
Ensembl chr19:47,754,120...47,811,368
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 increases expression ISO hydroquinone results in increased expression of ATP6V1C2 mRNA CTD PMID:31256213 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding increases expression ISO hydroquinone results in increased expression of AZGP1 mRNA CTD PMID:31256213 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
affects localization
ISO [ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
hydroquinone affects the localization of BACH1 protein
CTD PMID:28645578 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO hydroquinone results in decreased expression of BAD mRNA CTD PMID:15452088 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO hydroquinone results in decreased expression of BAG1 mRNA CTD PMID:31256213 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO hydroquinone results in increased expression of BAMBI mRNA CTD PMID:31256213 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of BAX protein
CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]
CTD PMID:33771647 PMID:33932074 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO hydroquinone results in increased expression of BBC3 mRNA CTD PMID:23416264 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO hydroquinone results in decreased expression of BCL11A mRNA CTD PMID:31256213 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcl11b BAF chromatin remodeling complex subunit BCL11B decreases expression ISO hydroquinone results in decreased expression of BCL11B mRNA CTD PMID:31256213 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein] CTD PMID:28444915 PMID:33771647 PMID:33932074 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO hydroquinone results in decreased expression of BDH2 mRNA CTD PMID:31256213 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein
PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]
CTD PMID:28263894 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
decreases expression
ISO hydroquinone results in increased expression of BIRC3 mRNA
hydroquinone results in decreased expression of BIRC3 mRNA
CTD PMID:15452088 PMID:31256213 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]
CTD PMID:28886972 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO hydroquinone results in decreased expression of BNIP3 mRNA CTD PMID:15452088 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO hydroquinone results in decreased expression of BORA mRNA CTD PMID:23416264 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
JBrowse link
G Bpifc BPI fold containing family C increases expression ISO hydroquinone results in increased expression of BPIFC mRNA CTD PMID:31256213 NCBI chr 7:17,848,787...17,905,993
Ensembl chr 7:17,861,007...17,905,919
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO hydroquinone results in increased expression of BRCA1 protein CTD PMID:29421518 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO hydroquinone results in decreased expression of BST2 mRNA CTD PMID:31256213 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO hydroquinone results in increased expression of BTG2 mRNA CTD PMID:23416264 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO hydroquinone results in decreased expression of BUB3 mRNA CTD PMID:31256213 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO hydroquinone results in decreased expression of CA3 mRNA CTD PMID:31256213 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO hydroquinone results in decreased expression of CA9 mRNA CTD PMID:31256213 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Calb2 calbindin 2 increases expression ISO hydroquinone results in increased expression of CALB2 mRNA CTD PMID:31256213 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression ISO hydroquinone results in increased expression of CALCB mRNA CTD PMID:31256213 NCBI chr 1:168,966,465...168,970,125
Ensembl chr 1:168,966,465...168,970,125
JBrowse link
G Calhm6 calcium homeostasis modulator family member 6 decreases expression ISO hydroquinone results in decreased expression of CALHM6 mRNA CTD PMID:31256213 NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278
JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO hydroquinone results in decreased expression of CALML3 mRNA CTD PMID:31256213 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
JBrowse link
G Capn2 calpain 2 decreases activity ISO hydroquinone results in decreased activity of CAPN2 protein CTD PMID:9118890 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
decreases activity
decreases expression
ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]
hydroquinone results in increased cleavage of CASP3 protein
hydroquinone results in decreased activity of CASP3 protein
[hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein
hydroquinone results in decreased expression of CASP3 mRNA
CTD PMID:15337166 PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 decreases expression ISO hydroquinone results in decreased expression of CASP6 mRNA CTD PMID:15452088 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases cleavage
increases expression
decreases activity
multiple interactions
ISO hydroquinone results in increased cleavage of CASP7 protein
hydroquinone results in increased expression of CASP7 protein modified form
hydroquinone results in decreased activity of CASP7 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]
CTD PMID:19064679 PMID:22960397 PMID:28886972 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
hydroquinone results in increased activity of CASP8 protein
CTD PMID:15777082 PMID:23776099 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 decreases expression
multiple interactions
increases expression
increases activity
increases cleavage
ISO hydroquinone results in decreased expression of CASP9 mRNA
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]
hydroquinone results in increased activity of CASP9 protein
hydroquinone results in increased cleavage of CASP9 protein
CTD PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases response to substance ISO CAT protein results in decreased susceptibility to hydroquinone CTD PMID:10193577 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO hydroquinone results in decreased expression of CAVIN2 mRNA CTD PMID:31256213 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Cbs cystathionine beta synthase increases expression ISO hydroquinone results in increased expression of CBS mRNA CTD PMID:31256213 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO hydroquinone results in decreased expression of CCDC127 mRNA CTD PMID:31256213 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893
JBrowse link
G Ccdc163 coiled-coil domain containing 163 decreases expression ISO hydroquinone results in decreased expression of CCDC163 mRNA CTD PMID:31256213 NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929
JBrowse link
G Ccdc8 coiled-coil domain containing 8 decreases expression ISO hydroquinone results in decreased expression of CCDC8 mRNA CTD PMID:31256213 NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090
JBrowse link
G Ccdc88c coiled-coil domain containing 88C decreases expression ISO hydroquinone results in decreased expression of CCDC88C mRNA CTD PMID:31256213 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO hydroquinone results in increased expression of CCL11 protein CTD PMID:17572062 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion
decreases expression
multiple interactions
increases secretion
increases expression
ISO hydroquinone results in decreased secretion of CCL2 protein
hydroquinone results in decreased expression of CCL2 mRNA
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein]
hydroquinone results in increased secretion of CCL2 protein
hydroquinone results in increased expression of CCL2 protein
CTD PMID:17572062 PMID:20946948 PMID:22302391 PMID:22465845 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO hydroquinone results in increased expression of CCL3 protein CTD PMID:17572062 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO hydroquinone results in increased expression of CCL4 protein CTD PMID:17572062 PMID:18353026 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO hydroquinone results in increased expression of CCL5 protein CTD PMID:17572062 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO hydroquinone affects the expression of CCN1 mRNA CTD PMID:15452088 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna1 cyclin A1 increases expression ISO hydroquinone results in increased expression of CCNA1 mRNA CTD PMID:31256213 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
decreases expression
ISO Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]
hydroquinone results in increased expression of CCND1 mRNA; hydroquinone results in increased expression of CCND1 protein
CTD PMID:28886972 PMID:33932074 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne2 cyclin E2 increases expression ISO hydroquinone results in increased expression of CCNE2 mRNA CTD PMID:23416264 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccnf cyclin F decreases expression ISO hydroquinone results in decreased expression of CCNF mRNA CTD PMID:23416264 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
JBrowse link
G Ccsap centriole, cilia and spindle-associated protein decreases expression ISO hydroquinone results in decreased expression of CCSAP mRNA CTD PMID:31256213 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein] CTD PMID:20054000 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:19148301 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule increases expression
multiple interactions
ISO hydroquinone results in increased expression of CD86 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]
CTD PMID:19148301 PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO hydroquinone results in decreased expression of CDCA2 mRNA CTD PMID:23416264 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO hydroquinone results in decreased expression of CDCA7 mRNA CTD PMID:31256213 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
JBrowse link
G Cdh26 cadherin 26 decreases expression ISO hydroquinone results in decreased expression of CDH26 mRNA CTD PMID:31256213 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO hydroquinone results in increased expression of CDKN1A mRNA CTD PMID:23416264 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO hydroquinone results in decreased expression of CDKN1C mRNA CTD PMID:31256213 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases expression
ISO CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of TP53 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]
hydroquinone results in decreased expression of CDKN2A mRNA; hydroquinone results in decreased expression of CDKN2A protein
CTD PMID:33771647 PMID:33932074 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdsn corneodesmosin increases expression ISO hydroquinone results in increased expression of CDSN mRNA CTD PMID:31256213 NCBI chr20:3,179,432...3,185,854
Ensembl chr20:3,179,438...3,184,250
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 increases expression ISO hydroquinone results in increased expression of CEMIP mRNA CTD PMID:31256213 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Cenpa centromere protein A decreases expression ISO hydroquinone results in decreased expression of CENPA mRNA CTD PMID:23416264 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO hydroquinone results in increased expression of CES1 mRNA CTD PMID:31256213 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cfap44 cilia and flagella associated protein 44 decreases expression ISO hydroquinone results in decreased expression of CFAP44 mRNA CTD PMID:31256213 NCBI chr11:56,199,050...56,284,053
Ensembl chr11:56,201,049...56,283,986
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO hydroquinone results in increased expression of CFLAR mRNA CTD PMID:31256213 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO hydroquinone results in increased expression of CH25H mRNA CTD PMID:31256213 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO hydroquinone results in increased expression of CHAC1 mRNA CTD PMID:31256213 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 decreases expression ISO hydroquinone results in decreased expression of CHP2 mRNA CTD PMID:31256213 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139
JBrowse link
G Chst2 carbohydrate sulfotransferase 2 increases expression ISO hydroquinone results in increased expression of CHST2 mRNA CTD PMID:31256213 NCBI chr 8:95,960,067...95,965,803
Ensembl chr 8:95,959,826...95,966,955
JBrowse link
G Clca4 chloride channel accessory 4 decreases expression ISO hydroquinone results in decreased expression of CLCA4 mRNA CTD PMID:31256213 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089
JBrowse link
G Cldn8 claudin 8 decreases expression ISO hydroquinone results in decreased expression of CLDN8 mRNA CTD PMID:31256213 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513
JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO hydroquinone results in increased expression of CLIC3 mRNA CTD PMID:31256213 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018
JBrowse link
G Clmp CXADR-like membrane protein increases expression ISO hydroquinone results in increased expression of CLMP mRNA CTD PMID:31256213 NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO hydroquinone results in decreased expression of CMPK2 mRNA CTD PMID:31256213 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cnfn cornifelin increases expression ISO hydroquinone results in increased expression of CNFN mRNA CTD PMID:31256213 NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747
JBrowse link
G Cnmd chondromodulin increases response to substance
increases expression
multiple interactions
ISO CNMD protein results in increased susceptibility to hydroquinone
hydroquinone results in increased expression of CNMD mRNA
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]
CTD PMID:19525446 NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO hydroquinone results in increased expression of COL1A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]
CTD PMID:18055817 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein CTD PMID:29908986 PMID:29935983 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
increases expression
multiple interactions
ISO hydroquinone results in decreased expression of COL4A1 mRNA
hydroquinone results in increased expression of COL4A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]
CTD PMID:18055817 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO hydroquinone results in decreased expression of COL5A2 mRNA CTD PMID:31256213 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Crct1 cysteine-rich C-terminal 1 increases expression ISO hydroquinone results in increased expression of CRCT1 mRNA CTD PMID:31256213 Ensembl chr 2:178,634,092...178,634,394 JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO hydroquinone results in increased expression of CRISPLD2 mRNA CTD PMID:31256213 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein
hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]
CTD PMID:7884313 PMID:15129224 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 increases expression ISO hydroquinone results in increased expression of CSGALNACT1 mRNA CTD PMID:31256213 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 decreases expression ISO hydroquinone results in decreased expression of CSRNP3 mRNA CTD PMID:31256213 NCBI chr 3:50,498,379...50,695,598
Ensembl chr 3:50,498,633...50,685,950
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO hydroquinone results in decreased expression of CSRP2 mRNA CTD PMID:31256213 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cst6 cystatin E/M increases expression ISO hydroquinone results in increased expression of CST6 mRNA CTD PMID:31256213 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO hydroquinone results in increased expression of CTH mRNA CTD PMID:31256213 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
decreases expression
ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein] CTD PMID:28886972 PMID:30567741 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO hydroquinone results in decreased expression of CXCL12 mRNA CTD PMID:22960397 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO hydroquinone affects the localization of CYCS protein CTD PMID:15777082 PMID:15816534 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects response to substance
increases expression
ISO CYP1A1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of CYP1A1 mRNA
CTD PMID:8242868 PMID:23416264 PMID:31256213 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone CTD PMID:8211999 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects response to substance ISO CYP2B1 protein affects the susceptibility to hydroquinone CTD PMID:8242868 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP
ISO
[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]
hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]
CTD PMID:8211999 PMID:15051535 PMID:30567741 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO hydroquinone results in increased expression of CYP4F18 mRNA CTD PMID:23940708 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cysrt1 cysteine rich tail 1 increases expression ISO hydroquinone results in increased expression of CYSRT1 mRNA CTD PMID:31256213 NCBI chr 3:8,054,195...8,057,846
Ensembl chr 3:8,053,482...8,059,721
JBrowse link
G Dap death-associated protein decreases expression ISO hydroquinone results in decreased expression of DAP mRNA CTD PMID:15452088 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dapl1 death associated protein-like 1 decreases expression ISO hydroquinone results in decreased expression of DAPL1 mRNA CTD PMID:31256213 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO hydroquinone results in increased expression of DAPP1 mRNA CTD PMID:31256213 NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO hydroquinone results in decreased expression of DBT mRNA CTD PMID:31256213 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 increases expression ISO hydroquinone results in increased expression of DCUN1D3 mRNA CTD PMID:31256213 NCBI chr 1:174,243,001...174,285,647
Ensembl chr 1:66,494,848...66,496,343
Ensembl chr 1:66,494,848...66,496,343
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO hydroquinone results in decreased expression of DDAH1 mRNA CTD PMID:31256213 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO hydroquinone results in increased expression of DDIT3 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO hydroquinone results in increased expression of DDIT4 mRNA CTD PMID:23416264 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO hydroquinone results in decreased expression of DEPDC7 mRNA CTD PMID:31256213 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO hydroquinone results in decreased expression of DFFB mRNA CTD PMID:31256213 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression ISO hydroquinone affects the expression of DKK1 mRNA CTD PMID:22960397 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO hydroquinone results in increased expression of DNAJA1 mRNA CTD PMID:15452088 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:15452088 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dner delta/notch-like EGF repeat containing decreases expression ISO hydroquinone results in decreased expression of DNER mRNA CTD PMID:31256213 NCBI chr 9:85,586,985...85,902,820
Ensembl chr 9:85,586,987...85,902,637
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
affects expression
ISO hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein
hydroquinone affects the expression of DNMT1 mRNA
CTD PMID:22245671 PMID:27979589 PMID:31899212 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein
hydroquinone results in increased expression of DNMT3A mRNA
CTD PMID:22245671 PMID:27979589 PMID:31899212 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
affects expression
ISO hydroquinone results in decreased expression of DNMT3B mRNA
Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]
CTD PMID:22245671 PMID:31899212 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO hydroquinone results in decreased expression of DTX3L mRNA CTD PMID:31256213 NCBI chr11:64,814,926...64,824,538
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO hydroquinone results in decreased expression of DUSP19 mRNA CTD PMID:31256213 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO hydroquinone results in increased expression of DUSP5 mRNA CTD PMID:31256213 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO hydroquinone results in increased expression of DUSP6 mRNA CTD PMID:31256213 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 decreases expression ISO hydroquinone results in decreased expression of DZIP1 mRNA CTD PMID:31256213 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO hydroquinone results in increased expression of E2F1 mRNA; hydroquinone results in increased expression of E2F1 protein CTD PMID:33932074 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E4f1 E4F transcription factor 1 increases expression
affects response to substance
multiple interactions
ISO hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein
E4F1 protein affects the susceptibility to hydroquinone
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form
CTD PMID:30448557 PMID:30506647 NCBI chr10:13,471,478...13,495,018
Ensembl chr10:13,474,456...13,485,974
JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO hydroquinone results in increased expression of ECM2 mRNA CTD PMID:31256213 NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
JBrowse link
G Edn1 endothelin 1 decreases expression ISO hydroquinone results in decreased expression of EDN1 mRNA CTD PMID:31256213 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 decreases expression ISO hydroquinone results in decreased expression of EDN2 mRNA CTD PMID:31256213 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO hydroquinone results in decreased expression of EEF2K mRNA CTD PMID:31256213 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA CTD PMID:32198055 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Egr3 early growth response 3 increases expression ISO hydroquinone results in increased expression of EGR3 mRNA CTD PMID:31256213 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO hydroquinone results in decreased expression of EHMT2 protein CTD PMID:27979589 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 decreases expression ISO hydroquinone results in decreased expression of EID3 mRNA CTD PMID:31256213 NCBI chr 7:20,860,073...20,861,395 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO hydroquinone results in increased expression of EIF4EBP1 mRNA CTD PMID:31256213 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO hydroquinone results in increased expression of ELF3 mRNA CTD PMID:23416264 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
JBrowse link
G Elf5 E74 like ETS transcription factor 5 increases expression ISO hydroquinone results in increased expression of ELF5 mRNA CTD PMID:31256213 NCBI chr 3:89,808,836...89,836,977
Ensembl chr 3:89,797,880...89,836,973
JBrowse link
G Elmod1 ELMO domain containing 1 increases expression ISO hydroquinone results in increased expression of ELMOD1 mRNA CTD PMID:31256213 NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO hydroquinone results in increased expression of ELOVL4 mRNA CTD PMID:31256213 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO hydroquinone results in decreased expression of ELOVL5 mRNA CTD PMID:31256213 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 decreases expression ISO hydroquinone results in decreased expression of ELP2 mRNA CTD PMID:31256213 NCBI chr18:15,885,940...15,921,564
Ensembl chr18:15,885,934...15,921,599
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression ISO hydroquinone results in increased expression of EPB41L3 mRNA CTD PMID:31256213 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO hydroquinone results in increased expression of EPS8L1 mRNA CTD PMID:31256213 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524
JBrowse link
G Ereg epiregulin increases expression ISO hydroquinone results in increased expression of EREG mRNA CTD PMID:31256213 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Erich5 glutamate-rich 5 decreases expression ISO hydroquinone results in decreased expression of ERICH5 mRNA CTD PMID:31256213 NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO hydroquinone results in decreased expression of ESR1 mRNA CTD PMID:31256213 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression ISO hydroquinone results in increased expression of ETV4 mRNA CTD PMID:31256213 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Exosc3 exosome component 3 decreases expression ISO hydroquinone results in decreased expression of EXOSC3 mRNA CTD PMID:31256213 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc6 exosome component 6 increases expression ISO hydroquinone results in increased expression of EXOSC6 mRNA CTD PMID:31256213 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO hydroquinone results in decreased expression of EZH2 protein CTD PMID:27979589 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO hydroquinone results in decreased expression of F2R mRNA CTD PMID:31256213 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO hydroquinone results in decreased expression of FADD mRNA CTD PMID:15452088 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fam117b family with sequence similarity 117, member B decreases expression ISO hydroquinone results in decreased expression of FAM117B mRNA CTD PMID:31256213 NCBI chr 9:61,340,291...61,418,531
Ensembl chr 9:61,340,249...61,408,483
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO hydroquinone results in decreased expression of FAM13A mRNA CTD PMID:31256213 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO hydroquinone results in increased expression of FAM43A mRNA CTD PMID:31256213 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO hydroquinone results in decreased expression of FAM83D mRNA CTD PMID:23416264 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO hydroquinone results in increased expression of FAS protein
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein
CTD PMID:23776099 PMID:28444915 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO hydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO hydroquinone results in decreased expression of FBXO5 mRNA CTD PMID:23416264 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO hydroquinone results in decreased expression of FGFR3 mRNA CTD PMID:31256213 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO hydroquinone results in increased expression of FIBIN mRNA CTD PMID:31256213 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
JBrowse link
G Fn1 fibronectin 1 affects expression ISO hydroquinone affects the expression of FN1 mRNA CTD PMID:15452088 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO hydroquinone results in decreased expression of FOS mRNA CTD PMID:15452088 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO hydroquinone results in increased expression of FOSL1 mRNA CTD PMID:31256213 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fry FRY microtubule binding protein increases expression ISO hydroquinone results in increased expression of FRY mRNA CTD PMID:31256213 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
JBrowse link
G Fsip1 fibrous sheath interacting protein 1 increases expression ISO hydroquinone results in increased expression of FSIP1 mRNA CTD PMID:31256213 NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO hydroquinone results in increased expression of FTH1 mRNA CTD PMID:15452088 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO hydroquinone results in decreased expression of FZD2 mRNA CTD PMID:31256213 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO hydroquinone results in increased expression of G0S2 mRNA CTD PMID:31256213 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO hydroquinone results in increased expression of GADD45A mRNA CTD PMID:23416264 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO hydroquinone results in decreased expression of GAS1 mRNA CTD PMID:31256213 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO hydroquinone results in decreased expression of GASK1B mRNA CTD PMID:31256213 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
JBrowse link
G Gata1 GATA binding protein 1 decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of GATA1 mRNA
decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
CTD PMID:21414390 PMID:23973255 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression
ISO hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroquinone results in decreased expression of GATA2 mRNA
CTD PMID:21414390 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO hydroquinone results in decreased expression of GBP2 mRNA CTD PMID:31256213 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein CTD PMID:30547568 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein CTD PMID:21059386 PMID:30547568 PMID:31256213 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gda guanine deaminase increases expression ISO hydroquinone results in increased expression of GDA mRNA CTD PMID:31256213 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO hydroquinone results in increased expression of GDPD3 mRNA CTD PMID:31256213 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO hydroquinone results in increased expression of GFPT1 mRNA CTD PMID:31256213 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
JBrowse link
G Gk glycerol kinase increases expression ISO hydroquinone results in increased expression of GK mRNA CTD PMID:31256213 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression ISO hydroquinone results in decreased expression of GLMP mRNA CTD PMID:31256213 NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960
JBrowse link
G Glrx glutaredoxin increases expression ISO hydroquinone results in increased expression of GLRX mRNA CTD PMID:31256213 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO hydroquinone results in decreased expression of GLUL mRNA CTD PMID:31256213 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO hydroquinone results in decreased expression of GMPR mRNA CTD PMID:31256213 NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO hydroquinone results in decreased expression of GOSR2 mRNA CTD PMID:31256213 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO hydroquinone results in increased expression of GOT1 mRNA CTD PMID:31256213 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO hydroquinone results in increased expression of GPAT3 mRNA CTD PMID:31256213 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO hydroquinone results in decreased expression of GPR155 mRNA CTD PMID:31256213 NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO hydroquinone results in decreased expression of GPRC5A mRNA CTD PMID:31256213 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO hydroquinone results in increased expression of GPX2 mRNA CTD PMID:31256213 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO hydroquinone results in increased expression of GRB10 mRNA CTD PMID:31256213 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression ISO hydroquinone affects the expression of GRB2 protein CTD PMID:20021034 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO hydroquinone results in increased expression of GRHL1 mRNA CTD PMID:31256213 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein] CTD PMID:28886972 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein] CTD PMID:15831208 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions
ISO hydroquinone results in increased expression of GSS protein
NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]
CTD PMID:21059386 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to hydroquinone CTD PMID:15141365 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gtpbp2 GTP binding protein 2 increases expression ISO hydroquinone results in increased expression of GTPBP2 mRNA CTD PMID:31256213 NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO hydroquinone results in increased expression of GUCY1B1 mRNA CTD PMID:31256213 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gvin1 GTPase, very large interferon inducible 1 decreases expression ISO hydroquinone results in decreased expression of GVINP1 mRNA CTD PMID:31256213 NCBI chr 1:160,279,767...160,306,701
Ensembl chr 1:160,277,126...160,306,331
JBrowse link
G Gypa glycophorin A decreases expression ISO hydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr19:27,450,311...27,465,940 JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-4 mRNA CTD PMID:23416264 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-5 mRNA CTD PMID:23416264 NCBI chr17:42,726,189...42,726,857
Ensembl chr17:42,726,127...42,769,160
JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO hydroquinone results in decreased expression of H2AC12 mRNA CTD PMID:23416264 NCBI chr17:42,486,315...42,486,880 JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression ISO hydroquinone results in decreased expression of H2AC20 mRNA CTD PMID:23416264 NCBI chr 2:183,779,879...183,780,324 JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO hydroquinone results in decreased expression of H2AC21 mRNA CTD PMID:23416264 NCBI chr 2:183,779,385...183,779,777 JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
affects localization
increases expression
ISO [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [POLH mutant form results in increased susceptibility to hydroquinone] which results in increased expression of H2AX protein; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
hydroquinone results in increased phosphorylation of H2AX protein
hydroquinone affects the localization of H2AX protein modified form
CTD PMID:17875398 PMID:18835433 PMID:20036648 PMID:21267443 PMID:22981619 More... NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO hydroquinone results in decreased expression of H4C3 mRNA CTD PMID:23416264
G H4f3 H1.3 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-3 mRNA CTD PMID:23416264 NCBI chr17:41,528,576...41,554,586
Ensembl chr17:41,529,667...41,552,334
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA] CTD PMID:21414390 PMID:23973255 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO hydroquinone results in increased expression of HBEGF mRNA CTD PMID:31256213 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO hydroquinone results in increased expression of HDAC1 protein CTD PMID:30448557 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 increases expression ISO hydroquinone results in increased expression of HDAC2 protein CTD PMID:30448557 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO hydroquinone results in increased expression of HDAC9 mRNA CTD PMID:31256213 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
JBrowse link
G Hfe homeostatic iron regulator decreases expression ISO hydroquinone results in decreased expression of HFE mRNA CTD PMID:31256213 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hist1h4m histone cluster 1, H4m decreases expression ISO hydroquinone results in decreased expression of H4C1 mRNA CTD PMID:23416264 NCBI chr17:42,698,054...42,698,365
Ensembl chr17:42,698,025...42,698,958
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 decreases expression ISO hydroquinone results in decreased expression of H2AC18 mRNA CTD PMID:23416264 NCBI chr 2:183,808,398...183,808,922 JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression ISO hydroquinone results in decreased expression of H4C2 mRNA CTD PMID:23416264 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO hydroquinone results in decreased expression of HJURP mRNA CTD PMID:23416264 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 PMID:23973255 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO hydroquinone results in decreased expression of HMGB2 mRNA CTD PMID:23416264 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of HMOX1 mRNA
ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]
hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein
CTD PMID:17464197 PMID:21059386 PMID:28645578 PMID:29508652 PMID:30547568 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hotairm1 Hoxa transcript antisense RNA, myeloid-specific 1 multiple interactions
affects expression
affects methylation
ISO Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter] CTD PMID:31899212 NCBI chr 4:81,258,793...81,262,291 JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
affects expression
ISO 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]
hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein
CTD PMID:26047893 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO hydroquinone results in increased expression of HSD17B2 mRNA CTD PMID:31256213 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression ISO hydroquinone results in increased expression of HSPA13 mRNA CTD PMID:31256213 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO hydroquinone results in increased expression of HSPA2 mRNA CTD PMID:15452088 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO hydroquinone results in decreased expression of HYLS1 mRNA CTD PMID:23416264 NCBI chr 8:33,913,016...33,922,125
Ensembl chr 8:33,912,692...33,921,760
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO hydroquinone results in increased expression of ID1 mRNA CTD PMID:31256213 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO hydroquinone results in decreased expression of ID3 mRNA CTD PMID:31256213 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein increases expression ISO hydroquinone results in increased expression of ID4 mRNA CTD PMID:31256213 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
JBrowse link
G Ier3 immediate early response 3 increases expression ISO hydroquinone results in increased expression of IER3 mRNA CTD PMID:31256213 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO hydroquinone results in decreased expression of IFI44 mRNA CTD PMID:31256213 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO hydroquinone results in decreased expression of IFI44L mRNA CTD PMID:31256213 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO hydroquinone results in decreased expression of IFIH1 mRNA CTD PMID:31256213 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO hydroquinone results in decreased expression of IFIT3 mRNA CTD PMID:31256213 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression ISO hydroquinone results in decreased expression of IFITM1 mRNA CTD PMID:31256213 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
JBrowse link
G Ifng interferon gamma multiple interactions ISO hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:3137358 PMID:7884313 PMID:22465845 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO hydroquinone results in increased expression of IFRD1 mRNA CTD PMID:31256213 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form] CTD PMID:28886972 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO hydroquinone results in decreased expression of IGFBP3 mRNA CTD PMID:31256213 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]
CTD PMID:17464197 PMID:17572062 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
hydroquinone results in increased expression of IL12B mRNA
CTD PMID:15894107 PMID:17464197 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il17a interleukin 17A increases secretion EXP hydroquinone results in increased secretion of IL17A protein CTD PMID:29935983 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
decreases cleavage
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]
hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein
hydroquinone results in decreased cleavage of IL1A protein
CTD PMID:1868253 PMID:8548860 PMID:9118901 PMID:28836394 PMID:31256213 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta decreases cleavage
increases expression
decreases secretion
multiple interactions
ISO
EXP
hydroquinone results in decreased cleavage of IL1B protein
hydroquinone results in increased expression of IL1B mRNA
hydroquinone results in decreased secretion of IL1B protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:8548860 PMID:9118901 PMID:17464197 PMID:19148301 PMID:22717997 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1f10 interleukin 1 family member 10 increases expression ISO hydroquinone results in increased expression of IL1F10 mRNA CTD PMID:31256213 NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439
JBrowse link
G Il2 interleukin 2 multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] CTD PMID:9571986 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA] CTD PMID:17464197 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il33 interleukin 33 decreases expression ISO hydroquinone results in decreased expression of IL33 mRNA CTD PMID:31256213 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il36g interleukin 36, gamma increases expression ISO hydroquinone results in increased expression of IL36G mRNA CTD PMID:31256213 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO hydroquinone results in increased expression of IL36RN mRNA CTD PMID:31256213 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il4 interleukin 4 multiple interactions ISO hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein] CTD PMID:12153512 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
EXP
ISO
[COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone results in decreased secretion of IL6 protein
CTD PMID:17464197 PMID:19148301 PMID:20054000 PMID:22302391 PMID:22717997 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO hydroquinone results in increased expression of INHBA mRNA CTD PMID:31256213 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO hydroquinone results in increased expression of INPP4B mRNA CTD PMID:31256213 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO hydroquinone results in decreased expression of IRS1 mRNA CTD PMID:31256213 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO hydroquinone results in decreased expression of ISG15 mRNA CTD PMID:31256213 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Itgb1 integrin subunit beta 1 decreases activity
decreases expression
ISO hydroquinone results in decreased activity of ITGB1 protein
hydroquinone results in decreased expression of ITGB1 mRNA
hydroquinone results in decreased expression of ITGB1 protein
CTD PMID:17464197 PMID:19148301 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
increases expression
ISO hydroquinone results in decreased expression of ITGB2 protein
hydroquinone results in decreased expression of ITGB2 mRNA
hydroquinone results in increased expression of ITGB2 protein
CTD PMID:17464197 PMID:19148301 PMID:21664406 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroquinone results in increased expression of ITGB3 protein CTD PMID:21664406 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Ivl involucrin increases expression ISO hydroquinone results in increased expression of IVL mRNA CTD PMID:31256213 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO hydroquinone results in decreased expression of JAG1 mRNA CTD PMID:22960397 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Jrk Jrk helix-turn-helix protein decreases expression ISO hydroquinone results in decreased expression of JRK mRNA CTD PMID:31256213 NCBI chr 7:106,590,662...106,595,345
Ensembl chr 7:106,589,484...106,596,371
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization ISO hydroquinone affects the localization of JUN protein CTD PMID:26807887 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 decreases expression ISO hydroquinone results in decreased expression of KBTBD6 mRNA CTD PMID:31256213 NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453
JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 decreases expression ISO hydroquinone results in decreased expression of KBTBD7 mRNA CTD PMID:31256213 NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO hydroquinone results in decreased expression of KCNJ15 mRNA CTD PMID:31256213 NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
JBrowse link
G Kdm6a lysine demethylase 6A decreases expression ISO hydroquinone results in decreased expression of KDM6A mRNA CTD PMID:31256213 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kics2 KICSTOR subunit 2 decreases expression ISO hydroquinone results in decreased expression of KICS2 mRNA CTD PMID:31256213 NCBI chr 7:57,284,213...57,299,070
Ensembl chr 7:57,284,192...57,297,486
JBrowse link
G Kif18a kinesin family member 18A decreases expression ISO hydroquinone results in decreased expression of KIF18A mRNA CTD PMID:23416264 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
JBrowse link
G Kitlg KIT ligand increases expression ISO hydroquinone results in increased expression of KITLG mRNA CTD PMID:22960397 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression ISO hydroquinone results in increased expression of KLF2 mRNA CTD PMID:31256213 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klf7 Kruppel like factor 7 increases expression ISO hydroquinone results in increased expression of KLF7 mRNA CTD PMID:31256213 NCBI chr 9:65,437,535...65,484,720
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Klhl31 kelch-like family member 31 decreases expression ISO hydroquinone results in decreased expression of KLHL31 mRNA CTD PMID:31256213 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873
JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression ISO hydroquinone results in increased expression of KLK6 mRNA CTD PMID:31256213 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO hydroquinone results in decreased expression of KLRG2 mRNA CTD PMID:31256213 NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein CTD PMID:28444915 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt13 keratin 13 decreases expression ISO hydroquinone results in decreased expression of KRT13 mRNA CTD PMID:31256213 NCBI chr10:85,052,122...85,056,032
Ensembl chr10:85,051,889...85,056,084
JBrowse link
G Krt19 keratin 19 decreases expression ISO hydroquinone results in decreased expression of KRT19 mRNA CTD PMID:31256213 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Krt23 keratin 23 increases expression ISO hydroquinone results in increased expression of KRT23 mRNA CTD PMID:31256213 NCBI chr10:84,434,675...84,450,722
Ensembl chr10:84,434,380...84,450,983
JBrowse link
G Krt24 keratin 24 decreases expression ISO hydroquinone results in decreased expression of KRT24 mRNA CTD PMID:31256213 NCBI chr10:84,232,408...84,237,299
Ensembl chr10:84,232,164...84,237,299
JBrowse link
G Krt78 keratin 78 increases expression ISO hydroquinone results in increased expression of KRT78 mRNA CTD PMID:31256213 NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021
JBrowse link
G Krt80 keratin 80 increases expression ISO hydroquinone results in increased expression of KRT80 mRNA CTD PMID:31256213 NCBI chr 7:132,464,807...132,485,026
Ensembl chr 7:132,463,218...132,485,508
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression
multiple interactions
ISO hydroquinone results in increased expression of LAMA4 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]
CTD PMID:18055817 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
JBrowse link
G Lasp1 LIM and SH3 protein 1 affects expression ISO hydroquinone affects the expression of LASP1 protein CTD PMID:20021034 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO hydroquinone results in increased expression of LCN2 mRNA CTD PMID:31256213 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]
hydroquinone results in decreased expression of LEF1 protein
CTD PMID:28886972 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lgalsl galectin-like increases expression ISO hydroquinone results in increased expression of LGALSL mRNA CTD PMID:31256213 NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression ISO hydroquinone results in decreased expression of LGR4 mRNA CTD PMID:31256213 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lipg lipase G, endothelial type increases expression ISO hydroquinone results in increased expression of LIPG mRNA CTD PMID:31256213 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Lmna lamin A/C affects expression ISO hydroquinone affects the expression of LMNA protein CTD PMID:17181942 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G LOC102548682 histone H4-like decreases expression ISO hydroquinone results in decreased expression of H4C6 mRNA CTD PMID:23416264 NCBI chr17:41,368,743...41,426,735 JBrowse link
G LOC102551184 histone H4-like decreases expression ISO hydroquinone results in decreased expression of H4C12 mRNA CTD PMID:23416264 NCBI chr17:41,526,192...41,575,488 JBrowse link
G LOC290595 hypothetical gene supported by AF152002 decreases expression ISO hydroquinone results in decreased expression of C10ORF99 mRNA CTD PMID:31256213 NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876
JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression ISO hydroquinone results in increased expression of LORICRIN mRNA CTD PMID:31256213 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807
JBrowse link
G Lrrc27 leucine rich repeat containing 27 decreases expression ISO hydroquinone results in decreased expression of LRRC27 mRNA CTD PMID:31256213 NCBI chr 1:194,004,967...194,035,087
Ensembl chr 1:194,005,182...194,035,084
JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO hydroquinone results in decreased expression of LRRIQ3 mRNA CTD PMID:31256213 NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339
JBrowse link
G Lss lanosterol synthase decreases expression ISO hydroquinone results in decreased expression of LSS mRNA CTD PMID:31256213 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO hydroquinone results in decreased expression of LY6E mRNA CTD PMID:31256213 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO hydroquinone results in increased expression of LY96 mRNA CTD PMID:31256213 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Lypd5 Ly6/Plaur domain containing 5 increases expression ISO hydroquinone results in increased expression of LYPD5 mRNA CTD PMID:31256213 NCBI chr 1:79,929,818...79,941,791
Ensembl chr 1:79,935,240...79,941,039
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO hydroquinone results in increased expression of MAFF mRNA CTD PMID:31256213 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr 4:126,205,667...126,811,354
Ensembl chr 4:126,206,816...126,811,691
JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO hydroquinone results in increased expression of MAP1B mRNA CTD PMID:31256213 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MAP7D2 mRNA CTD PMID:31256213 NCBI chr  X:35,372,453...35,488,073
Ensembl chr  X:35,372,700...35,488,091
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:15129224 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:15129224 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 increases expression ISO hydroquinone results in increased expression of MARCHF3 mRNA CTD PMID:31256213 NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression
multiple interactions
increases expression
ISO hydroquinone results in decreased expression of MBD2 mRNA
PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]
CTD PMID:22245671 PMID:30448557 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794
JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 decreases expression ISO hydroquinone results in decreased expression of MBNL3 mRNA CTD PMID:31256213 NCBI chr  X:130,641,942...130,737,179
Ensembl chr  X:130,648,538...130,737,056
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO hydroquinone results in increased expression of MBOAT2 mRNA CTD PMID:31256213 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO hydroquinone results in increased expression of MCTP1 mRNA CTD PMID:31256213 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833
JBrowse link
G Mctp2 multiple C2 and transmembrane domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MCTP2 mRNA CTD PMID:31256213 NCBI chr 1:125,769,932...126,002,886
Ensembl chr 1:125,771,233...126,002,928
JBrowse link
G Mettl21a methyltransferase like 21A decreases expression ISO hydroquinone results in decreased expression of METTL21A mRNA CTD PMID:31256213 NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550
JBrowse link
G Mettl7a methyltransferase like 7A decreases expression ISO hydroquinone results in decreased expression of METTL7A mRNA CTD PMID:31256213 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154
JBrowse link
G MGC105649 hypothetical LOC302884 increases expression ISO hydroquinone results in increased expression of C15ORF48 mRNA CTD PMID:31256213 NCBI chr 3:109,719,952...109,723,507
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO hydroquinone results in increased expression of MGST1 mRNA CTD PMID:15452088 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mid1 midline 1 decreases expression ISO hydroquinone results in decreased expression of MID1 mRNA CTD PMID:31256213 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353
JBrowse link
G Mir155 microRNA 155 multiple interactions
increases expression
ISO Doxorubicin promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; trichostatin A promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA] CTD PMID:30448557 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir486 microRNA 486 multiple interactions ISO hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; hydroquinone inhibits the reaction [Hemin results in increased expression of MIR486-1 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055
G Mmp1 matrix metallopeptidase 1 increases expression ISO hydroquinone results in increased expression of MMP1 mRNA CTD PMID:31256213 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] CTD PMID:18055817 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression ISO hydroquinone affects the expression of MMP15 mRNA CTD PMID:15452088 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
ISO hydroquinone results in decreased activity of MMP2 protein
[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]
CTD PMID:16936130 PMID:18055817 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 affects expression
increases expression
ISO hydroquinone affects the expression of MMP3 mRNA
hydroquinone results in increased expression of MMP3 mRNA
CTD PMID:15452088 PMID:31256213 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases secretion
ISO CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]
hydroquinone results in increased expression of MMP9 mRNA; hydroquinone results in increased expression of MMP9 protein
CTD PMID:17669387 PMID:26807887 PMID:33771647 PMID:33932074 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mob3b MOB kinase activator 3B decreases expression ISO hydroquinone results in decreased expression of MOB3B mRNA CTD PMID:31256213 NCBI chr 5:49,541,804...49,737,934
Ensembl chr 5:49,545,815...49,737,934
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor multiple interactions
decreases methylation
increases expression
ISO decitabine promotes the reaction [hydroquinone results in increased expression of MPL mRNA]
hydroquinone results in decreased methylation of MPL gene
CTD PMID:22245671 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases chemical synthesis
increases oxidation
ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein; [[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone; [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]; [MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone; [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
MPO protein results in increased chemical synthesis of hydroquinone
MPO protein results in increased oxidation of hydroquinone
CTD PMID:1666626 PMID:10994872 PMID:15777082 PMID:15935818 PMID:31248982 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpzl3 myelin protein zero-like 3 increases expression ISO hydroquinone results in increased expression of MPZL3 mRNA CTD PMID:31256213 NCBI chr 8:45,360,475...45,380,662
Ensembl chr 8:45,349,054...45,380,662
JBrowse link
G Mt1 metallothionein 1 increases expression ISO hydroquinone results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
EXP [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of MT2A mRNA] CTD PMID:33188856 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 decreases expression ISO hydroquinone results in decreased expression of MTHFD1 mRNA CTD PMID:31256213 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression ISO hydroquinone results in decreased expression of MTUS1 mRNA CTD PMID:31256213 NCBI chr16:51,202,497...51,347,791
Ensembl chr16:51,253,562...51,347,793
JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression ISO hydroquinone results in decreased expression of MX1 mRNA CTD PMID:31256213 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein] CTD PMID:12749906 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO hydroquinone results in decreased expression of MYCL mRNA CTD PMID:31256213 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO hydroquinone results in decreased expression of MYLIP mRNA CTD PMID:31256213 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Myo1f myosin IF decreases expression ISO hydroquinone results in decreased expression of MYO1F mRNA CTD PMID:31256213 NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911
JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 decreases expression ISO hydroquinone results in decreased expression of N4BP2L1 mRNA CTD PMID:31256213 NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO hydroquinone results in increased expression of NCF2 mRNA CTD PMID:31256213 NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression ISO hydroquinone results in decreased expression of NEDD4L mRNA CTD PMID:31256213 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137
JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO hydroquinone results in decreased expression of NEFH mRNA CTD PMID:31256213 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases expression ISO hydroquinone results in increased expression of NFATC2 mRNA CTD PMID:31256213 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO hydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein] CTD PMID:21059386 PMID:21643505 PMID:28645578 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
hydroquinone results in increased expression of NFKB1 protein
CTD PMID:15894107 PMID:30448557 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:20054000 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta decreases degradation ISO hydroquinone results in decreased degradation of NFKBIB protein CTD PMID:15894107 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO hydroquinone results in increased expression of NIBAN1 mRNA CTD PMID:31256213 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nid1 nidogen 1 decreases expression ISO hydroquinone results in decreased expression of NID1 mRNA CTD PMID:31256213 NCBI chr17:86,085,046...86,158,277
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Nipal3 NIPA-like domain containing 3 decreases expression ISO hydroquinone results in decreased expression of NIPAL3 mRNA CTD PMID:31256213 NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
hydroquinone results in decreased expression of NOS2 mRNA; hydroquinone results in decreased expression of NOS2 protein
CTD PMID:15831208 PMID:17464197 PMID:19148301 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
decreases response to substance
multiple interactions
ISO hydroquinone results in increased expression of NQO1 mRNA; hydroquinone results in increased expression of NQO1 protein
NQO1 protein results in decreased susceptibility to hydroquinone
ferric chloride promotes the reaction [hydroquinone results in increased expression of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]
CTD PMID:8652659 PMID:10368308 PMID:10393963 PMID:19525446 PMID:21059386 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO hydroquinone results in decreased expression of NR4A2 mRNA CTD PMID:31256213 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO hydroquinone results in decreased expression of NRAS mRNA CTD PMID:26047893 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Nudt16 nudix hydrolase 16 decreases expression ISO hydroquinone results in decreased expression of NUDT16 mRNA CTD PMID:31256213 NCBI chr 8:105,739,927...105,741,982
Ensembl chr 8:105,739,623...105,741,998
JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 increases expression ISO hydroquinone results in increased expression of NWD2 mRNA CTD PMID:31256213 NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO hydroquinone results in decreased expression of OAS1 mRNA CTD PMID:31256213 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO hydroquinone results in decreased expression of OAS2 mRNA CTD PMID:31256213 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO hydroquinone results in increased expression of OASL mRNA CTD PMID:31256213 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Ocln occludin multiple interactions EXP hydroquinone results in decreased degradation of and results in increased expression of OCLN protein CTD PMID:27587462 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Olah oleoyl-ACP hydrolase increases expression ISO hydroquinone results in increased expression of OLAH mRNA CTD PMID:31256213 NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518
JBrowse link
G Olr1356 olfactory receptor 1356 decreases expression ISO hydroquinone results in decreased expression of OR2C1 mRNA CTD PMID:31256213 NCBI chr10:11,682,890...11,683,828
Ensembl chr10:11,681,001...11,692,105
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 increases expression ISO hydroquinone results in increased expression of OVOL1 mRNA CTD PMID:31256213 NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831
JBrowse link
G P2rx4 purinergic receptor P2X 4 increases expression ISO hydroquinone results in increased expression of P2RX4 mRNA CTD PMID:31256213 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G Pa2g4 proliferation-associated 2G4 affects expression ISO hydroquinone affects the expression of PA2G4 protein CTD PMID:17181942 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pabpc4l poly(A) binding protein, cytoplasmic 4-like decreases expression ISO hydroquinone results in decreased expression of PABPC4L mRNA CTD PMID:31256213 NCBI chr 2:129,807,755...129,809,745
Ensembl chr 2:129,807,755...129,809,745
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO hydroquinone results in decreased expression of PAICS mRNA CTD PMID:31256213 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B decreases expression ISO hydroquinone results in decreased expression of PAIP2B mRNA CTD PMID:31256213 NCBI chr 4:116,291,376...116,323,422 JBrowse link
G Palmd palmdelphin decreases expression ISO hydroquinone results in decreased expression of PALMD mRNA CTD PMID:31256213 NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
affects response to substance
increases expression
increases response to substance
affects expression
multiple interactions
ISO hydroquinone results in increased cleavage of PARP1 protein
PARP1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of PARP1 protein
PARP1 protein results in increased susceptibility to hydroquinone
hydroquinone affects the expression of PARP1 protein
3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; hydroquinone results in increased expression of and results in increased cleavage of PARP1 protein; Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of TP53 protein]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]
CTD PMID:19064679 PMID:26047893 PMID:28263894 PMID:28444915 PMID:28886972 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 decreases expression ISO hydroquinone results in decreased expression of PARP9 mRNA CTD PMID:31256213 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO hydroquinone results in decreased expression of PBX1 mRNA CTD PMID:31256213 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO hydroquinone results in increased expression of PCK2 mRNA CTD PMID:31256213 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO hydroquinone results in decreased expression of PDCD4 mRNA CTD PMID:31256213 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pde11a phosphodiesterase 11A decreases expression ISO hydroquinone results in decreased expression of PDE11A mRNA CTD PMID:31256213 NCBI chr 3:60,913,562...61,297,154 JBrowse link
G Pde4b phosphodiesterase 4B decreases expression ISO hydroquinone results in decreased expression of PDE4B mRNA CTD PMID:31256213 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of PDGFRB mRNA CTD PMID:32198055 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases activity ISO hydroquinone metabolite results in decreased activity of PDPK1 protein; hydroquinone results in decreased activity of PDPK1 protein CTD PMID:20054000 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression ISO hydroquinone results in increased expression of PECAM1 protein CTD PMID:21664406 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO hydroquinone results in decreased expression of PEG3 mRNA CTD PMID:31256213 NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671
JBrowse link
G Pgls 6-phosphogluconolactonase affects expression ISO hydroquinone affects the expression of PGLS protein CTD PMID:17181942 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 increases expression ISO hydroquinone results in increased expression of PGLYRP4 mRNA CTD PMID:31256213 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO hydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:31256213 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression ISO hydroquinone results in decreased expression of PIK3C3 mRNA CTD PMID:31256213 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 decreases expression ISO hydroquinone results in decreased expression of PIK3IP1 mRNA CTD PMID:31256213 NCBI chr14:78,203,539...78,216,616
Ensembl chr14:78,204,053...78,216,608
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein] CTD PMID:28836394 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO hydroquinone results in increased expression of PIM1 mRNA CTD PMID:31256213 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO hydroquinone results in decreased expression of PITX2 mRNA CTD PMID:31256213 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha decreases expression ISO hydroquinone results in decreased expression of PKIA mRNA CTD PMID:31256213 NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282
JBrowse link
G Pkp2 plakophilin 2 increases expression ISO hydroquinone results in increased expression of PKP2 mRNA CTD PMID:31256213 NCBI chr11:84,661,783...84,727,730 JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 increases expression ISO hydroquinone results in increased expression of PLCXD1 mRNA CTD PMID:31256213 NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392
JBrowse link
G Pld1 phospholipase D1 decreases expression ISO hydroquinone results in decreased expression of PLD1 mRNA CTD PMID:31256213 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Pllp plasmolipin decreases expression ISO hydroquinone results in decreased expression of PLLP mRNA CTD PMID:31256213 NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892
JBrowse link
G Pmfbp1 polyamine modulated factor 1 binding protein 1 increases expression ISO hydroquinone results in increased expression of PMFBP1 mRNA CTD PMID:31256213 NCBI chr19:37,443,432...37,507,880
Ensembl chr19:37,458,108...37,507,879
JBrowse link
G Polh DNA polymerase eta increases response to substance
multiple interactions
ISO POLH mutant form results in increased susceptibility to hydroquinone
[POLH mutant form results in increased susceptibility to hydroquinone] which results in increased expression of H2AX protein
CTD PMID:22981619 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723
JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO hydroquinone results in decreased expression of POLR1B mRNA CTD PMID:31256213 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO hydroquinone results in increased expression of PPARD mRNA CTD PMID:31256213 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO hydroquinone results in increased expression of PPM1D mRNA CTD PMID:23416264 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO hydroquinone results in increased expression of PPP1R15A mRNA CTD PMID:31256213 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions ISO PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha multiple interactions ISO PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr13:102,931,264...102,975,661
Ensembl chr13:102,931,264...102,975,661
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 decreases expression ISO hydroquinone results in decreased expression of PPTC7 mRNA CTD PMID:31256213 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO hydroquinone results in increased expression of PRDM1 mRNA CTD PMID:31256213 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO hydroquinone results in increased expression of PRDX1 mRNA CTD PMID:15452088 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO hydroquinone results in increased expression of PRKDC mRNA; hydroquinone results in increased expression of PRKDC protein CTD PMID:20036648 PMID:23940708 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prr9 proline rich 9 increases expression ISO hydroquinone results in increased expression of PRR9 mRNA CTD PMID:31256213 NCBI chr 2:177,599,483...177,600,849
Ensembl chr 2:177,599,483...177,600,849
JBrowse link
G Prss3 serine protease 3 increases expression ISO hydroquinone results in increased expression of PRSS3 mRNA CTD PMID:31256213 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562
JBrowse link
G Psapl1 prosaposin-like 1 increases expression ISO hydroquinone results in increased expression of PSAPL1 mRNA CTD PMID:31256213 NCBI chr14:74,544,646...74,547,206
Ensembl chr14:74,544,646...74,547,206
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 decreases expression ISO hydroquinone results in decreased expression of PSRC1 mRNA CTD PMID:23416264 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression ISO hydroquinone results in decreased expression of PTGR2 mRNA CTD PMID:31256213 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO hydroquinone results in increased expression of PTGS2 mRNA CTD PMID:31256213 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein CTD PMID:31248982 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Pygb glycogen phosphorylase B increases expression ISO hydroquinone results in increased expression of PYGB mRNA CTD PMID:31256213 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression ISO hydroquinone results in increased expression of QPCT mRNA CTD PMID:31256213 NCBI chr 6:15,964,656...15,996,925
Ensembl chr 6:15,964,657...15,996,711
JBrowse link
G Rab30 RAB30, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB30 mRNA CTD PMID:31256213 NCBI chr 1:146,803,652...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO hydroquinone results in increased expression of RAB3B mRNA CTD PMID:31256213 NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
JBrowse link
G Rab7b Rab7b, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB7B mRNA CTD PMID:31256213 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Rabgap1l RAB GTPase activating protein 1-like decreases expression ISO hydroquinone results in decreased expression of RABGAP1L mRNA CTD PMID:31256213 NCBI chr13:72,464,114...73,059,845
Ensembl chr13:72,468,110...73,059,984
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAP1A protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein] CTD PMID:32198055 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein; hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression
decreases expression
multiple interactions
ISO hydroquinone results in increased expression of RB protein
hydroquinone results in decreased expression of RB1 mRNA; hydroquinone results in decreased expression of RB1 protein
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; hydroquinone results in decreased expression of and results in increased phosphorylation of RB1 protein; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]
CTD PMID:26047893 PMID:30506647 PMID:33771647 PMID:33932074 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 increases expression ISO hydroquinone results in increased expression of RBCK1 mRNA CTD PMID:31256213 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
JBrowse link
G Rdh12 retinol dehydrogenase 12 increases expression ISO hydroquinone results in increased expression of RDH12 mRNA CTD PMID:31256213 NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs decreases expression ISO hydroquinone results in decreased expression of RECK mRNA CTD PMID:31256213 NCBI chr 5:58,102,915...58,169,513
Ensembl chr 5:58,102,981...58,169,502
JBrowse link