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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:monosaccharide sulfate
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Accession:CHEBI:24589 term browser browse the term
Definition:Any carbohydrate sulfate that is a monosaccharide carrying at least one O-sulfo substituent.
Synonyms:related_synonym: monosaccharide sulfates


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beta-D-glucosamine 6-sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of ACSL1 mRNA CTD PMID:19520133 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 mRNA] CTD PMID:21877189 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of CEBPA mRNA; glucosamine 6-O-sulfate results in decreased expression of CEBPA protein CTD PMID:19520133 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of CHUK protein] CTD PMID:21877189 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of FABP4 mRNA CTD PMID:19520133 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of FAS mRNA CTD PMID:19520133 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:21877189 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:21877189 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:21877189 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lep leptin decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of LEP mRNA CTD PMID:19520133 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of LIPE mRNA CTD PMID:19520133 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of LPL mRNA CTD PMID:19520133 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21877189 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21877189 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein] CTD PMID:21877189 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:21877189 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21877189 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A protein] CTD PMID:21877189 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plin1 perilipin 1 decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of PLIN1 mRNA CTD PMID:19520133 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of PPARG mRNA; glucosamine 6-O-sulfate results in decreased expression of PPARG protein CTD PMID:19520133 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21877189 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein] CTD PMID:21877189 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO glucosamine 6-O-sulfate results in decreased expression of SREBF1 mRNA; glucosamine 6-O-sulfate results in decreased expression of SREBF1 protein CTD PMID:19520133 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:21877189 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      chemical role 19283
        catalyst 8054
          sulfuric acid 8015
            sulfuric acid derivative 8015
              organic sulfate 1938
                carbohydrate sulfate 1414
                  monosaccharide sulfate 24
                    2-O-sulfo-3,4-di-O-methyl-alpha-L-rhamnose 0
                    3-O-sulfo-beta-D-galactose + 0
                    3-O-sulfo-beta-D-glucopyranose 0
                    3-aminopropyl N-acetyl-6-O-sulfo-beta-D-glucosaminide 0
                    D-galactose 4-sulfate 0
                    D-galactose 6-sulfate + 0
                    D-glucopyranose 6-sulfate 0
                    D-glucose 6-sulfate 0
                    D-glucuronic acid 3-sulfate 0
                    L-iduronic acid 2-sulfate 0
                    N-acetyl-6-O-sulfo-D-glucosamine 0
                    alpha-D-galactose 6-sulfate 0
                    ascorbic acid 2-sulfate 0
                    hexosamine sulfate + 24
                    theograndin II 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      chalcogen 19391
                        oxygen atom 19353
                          oxygen molecular entity 19353
                            hydroxides 19103
                              oxoacid 18235
                                chalcogen oxoacid 11493
                                  sulfur oxoacid 11097
                                    sulfuric acid 8015
                                      sulfuric acid derivative 8015
                                        sulfates 8012
                                          organic sulfate 1938
                                            carbohydrate sulfate 1414
                                              monosaccharide sulfate 24
                                                2-O-sulfo-3,4-di-O-methyl-alpha-L-rhamnose 0
                                                3-O-sulfo-beta-D-galactose + 0
                                                3-O-sulfo-beta-D-glucopyranose 0
                                                3-aminopropyl N-acetyl-6-O-sulfo-beta-D-glucosaminide 0
                                                D-galactose 4-sulfate 0
                                                D-galactose 6-sulfate + 0
                                                D-glucopyranose 6-sulfate 0
                                                D-glucose 6-sulfate 0
                                                D-glucuronic acid 3-sulfate 0
                                                L-iduronic acid 2-sulfate 0
                                                N-acetyl-6-O-sulfo-D-glucosamine 0
                                                alpha-D-galactose 6-sulfate 0
                                                ascorbic acid 2-sulfate 0
                                                hexosamine sulfate + 24
                                                theograndin II 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.