CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | heterodetic cyclic peptide |
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Accession: | CHEBI:24533
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browse the term
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Definition: | A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond. |
Synonyms: | related_synonym: | heterodetic cyclic peptides; peptide cyclique heterodetique; peptido ciclico heterodetico |
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Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
ISO |
Alpha-Amanitin inhibits the reaction [2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA] |
CTD |
PMID:10377250 |
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NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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Aicda |
activation-induced cytidine deaminase |
multiple interactions |
ISO |
[Dactinomycin co-treated with Alpha-Amanitin] inhibits the reaction [Estradiol results in increased expression of AICDA mRNA] |
CTD |
PMID:19139166 |
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NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
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Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions decreases expression |
ISO |
Polymyxin B inhibits the reaction [Alpha-Amanitin results in decreased expression of GAPDH mRNA] |
CTD |
PMID:26385100 |
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NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
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Gpt |
glutamic--pyruvic transaminase |
increases expression multiple interactions |
ISO |
Alpha-Amanitin results in increased expression of GPT protein [Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein]; Methylprednisolone inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein]; Polymyxin B inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein] |
CTD |
PMID:30891624 |
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NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
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Lhb |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
Alpha-Amanitin inhibits the reaction [LHB protein results in increased expression of NR4A1 mRNA] |
CTD |
PMID:11416027 |
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NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
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Mpo |
myeloperoxidase |
increases activity multiple interactions |
ISO |
Alpha-Amanitin results in increased activity of MPO protein [Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein]; Methylprednisolone inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein]; Polymyxin B inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein] |
CTD |
PMID:30891624 |
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NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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Nfkb1 |
nuclear factor kappa B subunit 1 |
affects localization |
ISO |
Alpha-Amanitin affects the localization of NFKB1 protein |
CTD |
PMID:26385100 PMID:30891624 |
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NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
multiple interactions |
EXP |
Alpha-Amanitin inhibits the reaction [LHB protein results in increased expression of NR4A1 mRNA] |
CTD |
PMID:11416027 |
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NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
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Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
Alpha-Amanitin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein] |
CTD |
PMID:21533478 |
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NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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Polr2a |
RNA polymerase II subunit A |
increases degradation |
ISO |
Alpha-Amanitin results in increased degradation of POLR2A protein |
CTD |
PMID:32193566 |
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NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
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Avpr1a |
arginine vasopressin receptor 1A |
multiple interactions increases activity |
ISO |
vasopressin, 1-(1-mercaptocyclohexaneacetic acid)-2-(O- methyl-L-tyrosine)-8-L-arginine- inhibits the reaction [Arginine Vasopressin results in increased activity of AVPR1A protein] |
CTD |
PMID:31323226 |
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NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
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Hspb1 |
heat shock protein family B (small) member 1 |
increases expression multiple interactions |
EXP |
Arginine Vasopressin results in increased expression of HSPB1 mRNA; Arginine Vasopressin results in increased expression of HSPB1 protein Pentobarbital inhibits the reaction [Arginine Vasopressin results in increased expression of HSPB1 mRNA]; Pentobarbital inhibits the reaction [Arginine Vasopressin results in increased expression of HSPB1 protein] |
CTD |
PMID:10839933 |
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NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
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Myl9 |
myosin light chain 9 |
increases phosphorylation |
EXP |
Arginine Vasopressin results in increased phosphorylation of MYL9 protein |
CTD |
PMID:15347643 |
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NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
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Nppa |
natriuretic peptide A |
decreases response to substance |
ISO |
NPPA protein results in decreased susceptibility to Arginine Vasopressin |
CTD |
PMID:8188982 |
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NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
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Hcrt |
hypocretin neuropeptide precursor |
decreases expression |
EXP |
salmon calcitonin results in decreased expression of HCRT mRNA |
CTD |
PMID:12686383 |
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NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430
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Pmch |
pro-melanin-concentrating hormone |
decreases expression |
EXP |
salmon calcitonin results in decreased expression of PMCH mRNA |
CTD |
PMID:12686383 |
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NCBI chr 7:28,655,206...28,656,522
Ensembl chr 7:28,654,733...28,657,522
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Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation multiple interactions |
EXP |
Colistin results in decreased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:28465020 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]]; rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein] |
CTD |
PMID:28465020 PMID:28842171 |
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NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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Bcl2 |
BCL2, apoptosis regulator |
decreases expression increases phosphorylation multiple interactions |
EXP |
Colistin results in decreased expression of BCL2 protein Colistin results in increased phosphorylation of BCL2 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]]; [Colistin co-treated with Anisomycin] results in increased phosphorylation of BCL2 protein; Curcumin inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein] |
CTD |
PMID:28465020 PMID:28842171 PMID:30138604 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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Becn1 |
beclin 1 |
increases expression multiple interactions |
EXP |
Colistin results in increased expression of BECN1 protein Anisomycin promotes the reaction [Colistin results in increased expression of BECN1 protein]; pyrazolanthrone inhibits the reaction [Colistin results in increased expression of BECN1 protein] |
CTD |
PMID:28842171 |
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NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
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Casp3 |
caspase 3 |
multiple interactions increases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]]; [Colistin co-treated with Anisomycin] results in increased cleavage of CASP3 protein; chrysin inhibits the reaction [Colistin results in increased expression of CASP3 protein]; Colistin results in increased activity of and results in increased cleavage of CASP3 protein; Curcumin inhibits the reaction [Colistin results in increased expression of CASP3 protein]; rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein] |
CTD |
PMID:28465020 PMID:28842171 PMID:30138604 PMID:30273961 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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Cat |
catalase |
decreases expression decreases activity multiple interactions |
EXP |
Colistin results in decreased expression of CAT protein Colistin results in decreased activity of CAT protein chrysin inhibits the reaction [Colistin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Colistin results in decreased expression of CAT protein] |
CTD |
PMID:30138604 PMID:30273961 |
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NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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Il6 |
interleukin 6 |
multiple interactions increases expression |
EXP |
Curcumin inhibits the reaction [Colistin results in increased expression of IL6 protein] |
CTD |
PMID:30138604 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases expression |
EXP |
chrysin inhibits the reaction [Colistin results in increased expression of MAP1LC3B protein] |
CTD |
PMID:30273961 |
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NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
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Mrgprx2 |
MAS related GPR family member X2 |
multiple interactions increases response to substance |
ISO |
MRGPRX2 protein affects the reaction [Colistin results in increased secretion of OGA protein] MRGPRX2 protein results in increased susceptibility to Colistin |
CTD |
PMID:31132327 |
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NCBI chr 1:103,743,746...103,760,945
Ensembl chr 1:103,741,503...103,760,913
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Oga |
O-GlcNAcase |
increases secretion multiple interactions |
ISO |
Colistin results in increased secretion of OGA protein MRGPRX2 protein affects the reaction [Colistin results in increased secretion of OGA protein] |
CTD |
PMID:31132327 |
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NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
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Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
EXP |
[Colistin co-treated with Anisomycin] results in increased cleavage of PARP1 protein |
CTD |
PMID:28842171 |
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NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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Sqstm1 |
sequestosome 1 |
increases degradation multiple interactions |
EXP |
Colistin results in increased degradation of SQSTM1 protein Anisomycin promotes the reaction [Colistin results in increased degradation of SQSTM1 protein]; pyrazolanthrone inhibits the reaction [Colistin results in increased degradation of SQSTM1 protein] |
CTD |
PMID:28842171 |
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NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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Tnf |
tumor necrosis factor |
increases expression increases secretion multiple interactions |
EXP ISO |
Colistin results in increased expression of TNF protein Colistin results in increased secretion of TNF protein Curcumin inhibits the reaction [Colistin results in increased expression of TNF protein] |
CTD |
PMID:30138604 PMID:31132327 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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Tp53 |
tumor protein p53 |
multiple interactions increases expression |
EXP |
Anisomycin promotes the reaction [Colistin results in increased expression of TP53 protein]; pyrazolanthrone inhibits the reaction [Colistin results in increased expression of TP53 protein] |
CTD |
PMID:28842171 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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Aqp2 |
aquaporin 2 |
increases expression multiple interactions |
ISO EXP |
Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein] |
CTD |
PMID:16495377 PMID:16675087 PMID:21734099 |
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NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
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Avpr2 |
arginine vasopressin receptor 2 |
multiple interactions |
EXP ISO |
[Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid |
CTD |
PMID:1399968 PMID:15685210 |
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NCBI chr X:156,889,006...156,892,707
Ensembl chr X:156,889,410...156,891,213
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Cftr |
CF transmembrane conductance regulator |
increases activity |
ISO |
Deamino Arginine Vasopressin results in increased activity of CFTR protein |
CTD |
PMID:15685210 |
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NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
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Cul5 |
cullin 5 |
increases expression |
EXP |
Deamino Arginine Vasopressin results in increased expression of CUL5 protein |
CTD |
PMID:21734099 |
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NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
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Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] |
CTD |
PMID:20056751 |
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NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
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Myl9 |
myosin light chain 9 |
increases phosphorylation multiple interactions |
EXP |
Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein] |
CTD |
PMID:15347643 |
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NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
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Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
increases expression |
EXP |
Deamino Arginine Vasopressin results in increased expression of NEDD4 protein |
CTD |
PMID:21734099 |
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NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
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Scnn1b |
sodium channel epithelial 1 subunit beta |
increases expression |
EXP |
Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA |
CTD |
PMID:11711512 |
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NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
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Scnn1g |
sodium channel epithelial 1 subunit gamma |
increases expression |
EXP |
Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA |
CTD |
PMID:11711512 |
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NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
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Vwf |
von Willebrand factor |
increases activity increases secretion |
ISO |
Deamino Arginine Vasopressin results in increased activity of VWF protein Deamino Arginine Vasopressin results in increased secretion of VWF protein |
CTD |
PMID:1837767 PMID:2738447 PMID:3259400 |
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NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
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Abcc2 |
ATP binding cassette subfamily C member 2 |
affects export |
EXP |
ABCC2 protein affects the export of Enkephalin, D-Penicillamine (2,5)- |
CTD |
PMID:15528320 |
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NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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Cckbr |
cholecystokinin B receptor |
affects response to substance |
ISO |
CCKBR protein affects the susceptibility to Enkephalin, D-Penicillamine (2,5)- |
CTD |
PMID:11880531 |
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NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
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Hnf4a |
hepatocyte nuclear factor 4, alpha |
increases secretion |
ISO |
HNF4A protein results in increased secretion of Enkephalin, D-Penicillamine (2,5)- |
CTD |
PMID:27160211 |
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NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
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Oprd1 |
opioid receptor, delta 1 |
multiple interactions affects binding increases expression |
EXP ISO |
[Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein] which results in decreased abundance of Aluminum; [Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein] which results in increased susceptibility to Cocaine; naltrindole inhibits the reaction [[Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein] which results in increased susceptibility to Cocaine] 7-hydroxymitragynine affects the reaction [Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein]; Buprenorphine inhibits the reaction [Enkephalin, D-Penicillamine (2,5)- analog binds to OPRD1 protein]; Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein Enkephalin, D-Penicillamine (2,5)- binds to OPRD1 protein Enkephalin, D-Penicillamine (2,5)- results in increased expression of OPRD1 mRNA |
CTD |
PMID:7477890 PMID:7562497 PMID:9302088 PMID:19279569 PMID:21866885 PMID:27192616 |
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NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
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Oprk1 |
opioid receptor, kappa 1 |
affects binding |
EXP |
Enkephalin, D-Penicillamine (2,5)- binds to OPRK1 protein |
CTD |
PMID:7562497 |
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NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
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Oprm1 |
opioid receptor, mu 1 |
affects binding |
EXP |
Enkephalin, D-Penicillamine (2,5)- binds to OPRM1 protein |
CTD |
PMID:7562497 |
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NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
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Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
affects transport affects uptake |
ISO EXP |
SLCO1A4 protein affects the transport of Enkephalin, D-Penicillamine (2,5)- SLCO1A4 protein affects the uptake of Enkephalin, D-Penicillamine (2,5)- |
CTD |
PMID:15528320 PMID:19833843 |
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NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
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Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
affects uptake |
EXP |
SLCO1B2 protein affects the uptake of Enkephalin, D-Penicillamine (2,5)- |
CTD |
PMID:15528320 |
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NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
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Tnf |
tumor necrosis factor |
increases secretion |
EXP |
Novorapid inhibits the reaction [Lipopolysaccharide increases secretion of Tnf protein in serum] |
RGD |
PMID:18078960 |
RGD:15023464 |
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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F2 |
coagulation factor II |
multiple interactions |
ISO |
lepirudin binds to and results in decreased activity of F2 protein |
CTD |
PMID:15080313 PMID:18449412 |
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NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
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Actg1 |
actin, gamma 1 |
increases expression |
EXP |
Microcystins results in increased expression of ACTG1 protein |
CTD |
PMID:22430071 |
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NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954 Ensembl chr10:75,643,054...75,644,954
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Alb |
albumin |
increases expression |
EXP |
Microcystins results in increased expression of ALB protein |
CTD |
PMID:22430071 |
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NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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Aldh9a1 |
aldehyde dehydrogenase 9 family, member A1 |
decreases expression |
EXP |
Microcystins results in decreased expression of ALDH9A1 protein |
CTD |
PMID:22430071 |
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NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
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Atp6v1b2 |
ATPase H+ transporting V1 subunit B2 |
decreases expression |
EXP |
Microcystins results in decreased expression of ATP6V1B2 protein |
CTD |
PMID:22430071 |
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NCBI chr16:22,326,537...22,350,143
Ensembl chr16:22,326,529...22,350,155
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Bax |
BCL2 associated X, apoptosis regulator |
increases expression decreases expression |
EXP |
Microcystins results in increased expression of BAX mRNA; Microcystins results in increased expression of BAX protein microcystin results in decreased expression of BAX |
CTD |
PMID:12411203 PMID:19760617 |
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NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression increases expression |
EXP |
Microcystins results in decreased expression of BCL2 mRNA; Microcystins results in decreased expression of BCL2 protein microcystin results in increased expression of BCL2 |
CTD |
PMID:12411203 PMID:19760617 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Capza2 |
capping actin protein of muscle Z-line subunit alpha 2 |
increases expression |
EXP |
Microcystins results in increased expression of CAPZA2 protein |
CTD |
PMID:22430071 |
|
NCBI chr 4:44,936,290...44,972,270
Ensembl chr 4:44,936,290...44,972,267
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G |
Cat |
catalase |
increases expression |
EXP |
microcystin results in increased expression of CAT mRNA; microcystin results in increased expression of CAT protein |
CTD |
PMID:19135122 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Dpp3 |
dipeptidylpeptidase 3 |
increases expression |
EXP |
Microcystins results in increased expression of DPP3 protein |
CTD |
PMID:22430071 |
|
NCBI chr 1:220,166,124...220,189,762
Ensembl chr 1:220,166,127...220,188,541
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
increases expression |
EXP |
Microcystins results in increased expression of DYNC1I1 protein |
CTD |
PMID:22430071 |
|
NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions |
EXP |
Microcystins analog results in increased expression of GCLC mRNA Buthionine Sulfoximine inhibits the reaction [Microcystins analog results in increased expression of GCLC mRNA] |
CTD |
PMID:24964298 |
|
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
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G |
Gdi1 |
GDP dissociation inhibitor 1 |
increases expression |
EXP |
Microcystins results in increased expression of GDI1 protein |
CTD |
PMID:22430071 |
|
NCBI chr X:156,400,734...156,407,396
Ensembl chr X:156,400,736...156,407,404
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G |
Gfap |
glial fibrillary acidic protein |
decreases expression increases degradation |
EXP |
Microcystins results in decreased expression of GFAP protein microcystin analog results in increased degradation of GFAP protein |
CTD |
PMID:22430071 PMID:27864109 |
|
NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
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G |
Golga3 |
golgin A3 |
decreases expression |
EXP |
Microcystins results in decreased expression of GOLGA3 protein |
CTD |
PMID:22430071 |
|
NCBI chr12:52,510,509...52,558,606
Ensembl chr12:52,512,970...52,558,606
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression multiple interactions |
EXP |
microcystin results in increased expression of GPX1 mRNA; Microcystins analog results in increased expression of GPX1 mRNA Buthionine Sulfoximine promotes the reaction [Microcystins analog results in increased expression of GPX1 mRNA] |
CTD |
PMID:19135122 PMID:24964298 |
|
NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
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G |
Grb2 |
growth factor receptor bound protein 2 |
decreases expression |
EXP |
Microcystins results in decreased expression of GRB2 protein |
CTD |
PMID:22430071 |
|
NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases expression |
EXP |
Buthionine Sulfoximine inhibits the reaction [Microcystins analog results in decreased expression of GSR mRNA] |
CTD |
PMID:24964298 |
|
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
decreases expression increases expression |
EXP |
Microcystins results in decreased expression of GSTA3 mRNA Microcystins results in increased expression of GSTA3 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
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G |
Gsta4 |
glutathione S-transferase alpha 4 |
decreases expression increases expression |
EXP |
Microcystins results in decreased expression of GSTA4 mRNA microcystin results in increased expression of GSTA4 mRNA; Microcystins results in increased expression of GSTA4 mRNA |
CTD |
PMID:19135122 PMID:19790251 |
|
NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
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G |
Gstk1 |
glutathione S-transferase kappa 1 |
affects expression increases expression |
EXP |
Microcystins affects the expression of GSTK1 mRNA Microcystins results in increased expression of GSTK1 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
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G |
Gstm1 |
glutathione S-transferase mu 1 |
affects expression |
EXP |
Microcystins affects the expression of GSTM1 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
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G |
Gstm2 |
glutathione S-transferase mu 2 |
decreases expression increases expression |
EXP |
Microcystins results in decreased expression of GSTM2 mRNA Microcystins results in increased expression of GSTM2 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
affects expression decreases expression |
EXP |
Microcystins affects the expression of GSTM3 mRNA Microcystins results in decreased expression of GSTM3 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
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G |
Gsto1 |
glutathione S-transferase omega 1 |
affects expression decreases expression |
EXP |
Microcystins affects the expression of GSTO1 mRNA Microcystins results in decreased expression of GSTO1 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
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G |
Gsto2 |
glutathione S-transferase omega 2 |
affects expression |
EXP |
Microcystins affects the expression of GSTO2 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 1:267,617,517...267,640,455
Ensembl chr 1:271,229,036...271,243,517 Ensembl chr 1:271,229,036...271,243,517
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions increases expression affects expression |
EXP |
Buthionine Sulfoximine inhibits the reaction [Microcystins analog results in increased expression of GSTP1 mRNA] Microcystins analog results in increased expression of GSTP1 mRNA; Microcystins results in increased expression of GSTP1 mRNA Microcystins affects the expression of GSTP1 mRNA |
CTD |
PMID:19790251 PMID:24964298 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
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G |
Gstt1 |
glutathione S-transferase theta 1 |
affects expression increases expression |
EXP |
Microcystins affects the expression of GSTT1 mRNA Microcystins results in increased expression of GSTT1 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
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G |
Gstt2 |
glutathione S-transferase, theta 2 |
decreases expression affects expression |
EXP |
Microcystins results in decreased expression of GSTT2 mRNA Microcystins affects the expression of GSTT2 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
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G |
Gstz1 |
glutathione S-transferase zeta 1 |
decreases expression affects expression |
EXP |
Microcystins results in decreased expression of GSTZ1 mRNA Microcystins affects the expression of GSTZ1 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Microcystins results in increased expression of HSPA5 protein |
CTD |
PMID:22430071 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
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G |
Ina |
internexin neuronal intermediate filament protein, alpha |
increases expression |
EXP |
Microcystins results in increased expression of INA mRNA; Microcystins results in increased expression of INA protein |
CTD |
PMID:22430071 |
|
NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
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G |
Lasp1 |
LIM and SH3 protein 1 |
increases expression |
EXP |
Microcystins results in increased expression of LASP1 protein |
CTD |
PMID:22430071 |
|
NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
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G |
Mapt |
microtubule-associated protein tau |
increases phosphorylation |
EXP |
Microcystins results in increased phosphorylation of MAPT protein |
CTD |
PMID:22430071 |
|
NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
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G |
Mgst1 |
microsomal glutathione S-transferase 1 |
affects expression increases expression |
EXP |
Microcystins affects the expression of MGST1 mRNA Microcystins results in increased expression of MGST1 mRNA |
CTD |
PMID:19790251 |
|
NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
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G |
Mtus2 |
microtubule associated scaffold protein 2 |
increases expression |
EXP |
Microcystins results in increased expression of MTUS2 protein |
CTD |
PMID:22430071 |
|
NCBI chr12:8,111,655...8,491,553
Ensembl chr12:8,111,667...8,418,966
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G |
Myl2 |
myosin light chain 2 |
increases expression |
EXP |
Microcystins results in increased expression of MYL2 protein |
CTD |
PMID:22430071 |
|
NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
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G |
Myl9 |
myosin light chain 9 |
increases phosphorylation |
EXP |
microcystin results in increased phosphorylation of MYL9 protein |
CTD |
PMID:18835913 |
|
NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
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G |
Necab1 |
N-terminal EF-hand calcium binding protein 1 |
increases expression |
EXP |
Microcystins results in increased expression of NECAB1 protein |
CTD |
PMID:22430071 |
|
NCBI chr 5:28,507,596...28,737,556
Ensembl chr 5:28,504,558...28,737,719
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
decreases expression |
EXP |
Microcystins results in decreased expression of PDIA3 protein |
CTD |
PMID:22430071 |
|
NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
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G |
Pdxp |
pyridoxal phosphatase |
decreases expression |
EXP |
Microcystins results in decreased expression of PDXP protein |
CTD |
PMID:22430071 |
|
NCBI chr 7:120,140,460...120,145,908
Ensembl chr 7:120,140,460...120,145,908
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G |
Ppp1cc |
protein phosphatase 1 catalytic subunit gamma |
decreases expression |
EXP |
Microcystins results in decreased expression of PPP1CC protein |
CTD |
PMID:22430071 |
|
NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030
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G |
Ppp1r1b |
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
increases expression |
EXP |
Microcystins results in increased expression of PPP1R1B protein |
CTD |
PMID:22430071 |
|
NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
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G |
Prdx2 |
peroxiredoxin 2 |
increases expression |
EXP |
Microcystins results in increased expression of PRDX2 protein |
CTD |
PMID:22430071 |
|
NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
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G |
Rpsa |
ribosomal protein SA |
increases expression |
EXP |
Microcystins results in increased expression of RPSA protein |
CTD |
PMID:22430071 |
|
NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
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G |
Sema7a |
semaphorin 7A (John Milton Hagen blood group) |
increases expression |
EXP |
Microcystins results in increased expression of SEMA7A protein |
CTD |
PMID:22430071 |
|
NCBI chr 8:62,723,788...62,746,530
Ensembl chr 8:62,723,788...62,745,868
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G |
Septin11 |
septin 11 |
increases expression decreases expression |
EXP |
Microcystins results in increased expression of SEPTIN11 protein Microcystins results in decreased expression of SEPTIN11 protein |
CTD |
PMID:22430071 |
|
NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
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G |
Septin5 |
septin 5 |
increases expression |
EXP |
Microcystins results in increased expression of SEPTIN5 mRNA; Microcystins results in increased expression of SEPTIN5 protein |
CTD |
PMID:22430071 |
|
NCBI chr11:86,516,377...86,522,169
Ensembl chr11:86,512,797...86,522,168
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G |
Septin8 |
septin 8 |
increases expression |
EXP |
Microcystins results in increased expression of SEPTIN8 protein |
CTD |
PMID:22430071 |
|
NCBI chr10:38,877,422...38,906,480
Ensembl chr10:38,877,422...38,906,482
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G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
increases uptake increases response to substance |
ISO |
SLCO1B2 protein results in increased uptake of Microcystins SLCO1B3 protein results in increased uptake of Microcystins SLCO1B3 protein results in increased susceptibility to microcystin analog |
CTD |
PMID:20171238 PMID:20472527 |
|
NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
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G |
Snca |
synuclein alpha |
increases expression |
EXP |
Microcystins results in increased expression of SNCA mRNA; Microcystins results in increased expression of SNCA protein |
CTD |
PMID:22430071 |
|
NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
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G |
Sod1 |
superoxide dismutase 1 |
increases expression |
EXP |
Microcystins results in increased expression of SOD1 protein |
CTD |
PMID:22430071 |
|
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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G |
Sod2 |
superoxide dismutase 2 |
increases expression |
EXP |
microcystin results in increased expression of SOD2 mRNA |
CTD |
PMID:19135122 |
|
NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
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G |
Stip1 |
stress-induced phosphoprotein 1 |
increases expression |
EXP |
Microcystins results in increased expression of STIP1 protein |
CTD |
PMID:22430071 |
|
NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
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G |
Tmod2 |
tropomodulin 2 |
decreases expression |
EXP |
Microcystins results in decreased expression of TMOD2 protein |
CTD |
PMID:22430071 |
|
NCBI chr 8:82,505,947...82,547,450
Ensembl chr 8:82,506,934...82,533,689
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G |
Tnni3 |
troponin I3, cardiac type |
increases expression |
EXP |
microcystin results in increased expression of TNNI3 protein |
CTD |
PMID:19135122 |
|
NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
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G |
Tp53 |
tumor protein p53 |
increases expression |
EXP |
Microcystins results in increased expression of TP53 mRNA; Microcystins results in increased expression of TP53 protein |
CTD |
PMID:19760617 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Tpi1 |
triosephosphate isomerase 1 |
increases expression |
EXP |
Microcystins results in increased expression of TPI1 protein |
CTD |
PMID:22430071 |
|
NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
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G |
Tpm1 |
tropomyosin 1 |
increases expression |
EXP |
Microcystins results in increased expression of TPM1 protein |
CTD |
PMID:22430071 |
|
NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
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G |
Trap1 |
TNF receptor-associated protein 1 |
increases expression |
EXP |
Microcystins results in increased expression of TRAP1 protein |
CTD |
PMID:22430071 |
|
NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
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G |
Tuba1c |
tubulin, alpha 1C |
decreases expression |
EXP |
Microcystins results in decreased expression of TUBA1C protein |
CTD |
PMID:22430071 |
|
NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
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G |
Tubb2b |
tubulin, beta 2B class IIb |
decreases expression |
EXP |
Microcystins results in decreased expression of TUBB2B protein |
CTD |
PMID:22430071 |
|
NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759
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G |
Tubb4b |
tubulin, beta 4B class IVb |
decreases expression |
EXP |
Microcystins results in decreased expression of TUBB4B protein |
CTD |
PMID:22430071 |
|
NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
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G |
Tufm |
Tu translation elongation factor, mitochondrial |
increases expression |
EXP |
Microcystins results in increased expression of TUFM protein |
CTD |
PMID:22430071 |
|
NCBI chr 1:197,903,582...197,907,189
Ensembl chr 1:197,903,582...197,907,189
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G |
Uchl3 |
ubiquitin C-terminal hydrolase L3 |
decreases expression |
EXP |
Microcystins results in decreased expression of UCHL3 protein |
CTD |
PMID:22430071 |
|
NCBI chr15:86,153,624...86,198,127
Ensembl chr15:86,153,628...86,198,127
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases export multiple interactions |
ISO |
ABCC2 protein results in increased export of microcystin-LF microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:31348918 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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G |
Gfap |
glial fibrillary acidic protein |
increases degradation |
EXP |
microcystin-LF results in increased degradation of GFAP protein |
CTD |
PMID:27864109 |
|
NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
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G |
Mapt |
microtubule-associated protein tau |
affects phosphorylation |
ISO |
microcystin-LF affects the phosphorylation of MAPT protein |
CTD |
PMID:21934130 |
|
NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
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G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
increases response to substance |
ISO |
SLCO1B3 protein results in increased susceptibility to microcystin-LF |
CTD |
PMID:20171238 |
|
NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
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|
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases export multiple interactions |
ISO |
ABCC2 protein results in increased export of microcystin RR microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:31348918 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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G |
Ace |
angiotensin I converting enzyme |
increases expression |
ISO |
microcystin RR results in increased expression of ACE mRNA; microcystin RR results in increased expression of ACE protein |
CTD |
PMID:28330766 |
|
NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
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G |
Agt |
angiotensinogen |
increases expression multiple interactions |
ISO |
microcystin RR results in increased expression of AGT mRNA; microcystin RR results in increased expression of AGT protein aliskiren inhibits the reaction [microcystin RR results in increased expression of AGT protein] |
CTD |
PMID:28330766 |
|
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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G |
Ahsa1 |
activator of Hsp90 ATPase activity 1 |
increases expression |
ISO |
microcystin RR results in increased expression of AHSA1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 6:111,296,168...111,304,224
Ensembl chr 6:111,296,417...111,304,224
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G |
Alb |
albumin |
decreases expression |
ISO |
microcystin RR results in decreased expression of ALB protein |
CTD |
PMID:28330766 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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G |
Arpc5 |
actin related protein 2/3 complex, subunit 5 |
decreases expression |
ISO |
microcystin RR results in decreased expression of ARPC5 protein |
CTD |
PMID:19111056 |
|
NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
decreases expression |
ISO |
microcystin RR results in decreased expression of ATP5PD protein |
CTD |
PMID:19111056 |
|
NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
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G |
Avp |
arginine vasopressin |
increases expression |
ISO |
microcystin RR results in increased expression of AVP protein |
CTD |
PMID:28330766 |
|
NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
microcystin RR results in increased expression of BAX protein |
CTD |
PMID:20196164 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
microcystin RR results in decreased expression of BCL2 protein |
CTD |
PMID:20196164 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
C1qbp |
complement C1q binding protein |
decreases expression |
ISO |
microcystin RR results in decreased expression of C1QBP protein |
CTD |
PMID:19111056 |
|
NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
|
|
G |
Capza1 |
capping actin protein of muscle Z-line subunit alpha 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of CAPZA1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
|
|
G |
Ccdc18 |
coiled-coil domain containing 18 |
increases expression |
ISO |
microcystin RR results in increased expression of CCDC18 protein |
CTD |
PMID:19111056 |
|
NCBI chr14:1,664,620...1,701,269 NCBI chr14:2,510,184...2,612,070
Ensembl chr14:2,509,363...2,610,929
|
|
G |
Cct8 |
chaperonin containing TCP1 subunit 8 |
increases expression |
ISO |
microcystin RR results in increased expression of CCT8 protein |
CTD |
PMID:19111056 |
|
NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
|
|
G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
microcystin RR results in decreased expression of CDK4 protein |
CTD |
PMID:19111056 |
|
NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
|
|
G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
decreases expression |
ISO |
microcystin RR results in decreased expression of CDKN2A protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
|
|
G |
Ciapin1 |
cytokine induced apoptosis inhibitor 1 |
increases expression |
ISO |
microcystin RR results in increased expression of CIAPIN1 protein |
CTD |
PMID:19111056 |
|
NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
|
|
G |
Clic4 |
chloride intracellular channel 4 |
increases expression |
ISO |
microcystin RR results in increased expression of CLIC4 protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
|
|
G |
Cox5a |
cytochrome c oxidase subunit 5A |
decreases expression |
ISO |
microcystin RR results in decreased expression of COX5A protein |
CTD |
PMID:19111056 |
|
NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
|
|
G |
Crkl |
CRK like proto-oncogene, adaptor protein |
increases expression |
ISO |
microcystin RR results in increased expression of CRKL protein |
CTD |
PMID:19111056 |
|
NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
|
|
G |
Csde1 |
cold shock domain containing E1 |
increases expression |
ISO |
microcystin RR results in increased expression of CSDE1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:205,525,194...205,552,987
Ensembl chr 2:205,525,204...205,552,991
|
|
G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of ECHS1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
|
|
G |
Eif2b3 |
eukaryotic translation initiation factor 2B subunit gamma |
increases expression |
ISO |
microcystin RR results in increased expression of EIF2B3 protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818
|
|
G |
Eif5a |
eukaryotic translation initiation factor 5A |
increases expression |
ISO |
microcystin RR results in increased expression of EIF5A protein |
CTD |
PMID:19111056 |
|
NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
|
|
G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
decreases expression |
ISO |
microcystin RR results in decreased expression of ERCC1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
|
|
G |
Erp29 |
endoplasmic reticulum protein 29 |
decreases expression |
ISO |
microcystin RR results in decreased expression of ERP29 protein |
CTD |
PMID:19111056 |
|
NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
|
|
G |
Esd |
esterase D |
decreases expression |
ISO |
microcystin RR results in decreased expression of ESD protein |
CTD |
PMID:19111056 |
|
NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
|
|
G |
Fabp5 |
fatty acid binding protein 5 |
decreases expression |
ISO |
microcystin RR results in decreased expression of FABP5 protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
|
|
G |
Flot1 |
flotillin 1 |
increases expression |
ISO |
microcystin RR results in increased expression of FLOT1 protein |
CTD |
PMID:19111056 |
|
NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396
|
|
G |
G3bp1 |
G3BP stress granule assembly factor 1 |
increases expression |
ISO |
microcystin RR results in increased expression of G3BP1 protein |
CTD |
PMID:19111056 |
|
NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
|
|
G |
Galnt13 |
polypeptide N-acetylgalactosaminyltransferase 13 |
decreases expression |
ISO |
microcystin RR results in decreased expression of GALNT13 protein |
CTD |
PMID:19111056 |
|
NCBI chr 3:39,967,056...40,625,144
Ensembl chr 3:40,038,336...40,624,530
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
increases activity |
ISO |
microcystin RR results in increased activity of GPT protein |
CTD |
PMID:28330766 |
|
NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
increases glutathionylation |
ISO |
GSTA1 protein results in increased glutathionylation of microcystin RR |
CTD |
PMID:23538035 |
|
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
increases glutathionylation |
ISO |
GSTM1 protein results in increased glutathionylation of microcystin RR |
CTD |
PMID:23538035 |
|
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
increases glutathionylation |
ISO |
GSTP1 protein results in increased glutathionylation of microcystin RR |
CTD |
PMID:23538035 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
increases glutathionylation |
ISO |
GSTT1 protein results in increased glutathionylation of microcystin RR |
CTD |
PMID:23538035 |
|
NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
|
|
G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression |
ISO |
microcystin RR results in increased expression of HSPA1B protein |
CTD |
PMID:19111056 |
|
NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
microcystin RR results in increased expression of HSPA5 protein |
CTD |
PMID:20196164 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
|
|
G |
Hypk |
Huntingtin interacting protein K |
decreases expression |
ISO |
microcystin RR results in decreased expression of HYPK protein |
CTD |
PMID:19111056 |
|
NCBI chr 3:113,423,684...113,425,064
Ensembl chr 3:113,423,693...113,424,846
|
|
G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
increases expression |
ISO |
microcystin RR results in increased expression of IDH3A protein |
CTD |
PMID:19111056 |
|
NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
|
|
G |
Immt |
inner membrane mitochondrial protein |
increases expression decreases expression |
ISO |
microcystin RR results in increased expression of IMMT protein microcystin RR results in decreased expression of IMMT protein |
CTD |
PMID:19111056 |
|
NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
|
|
G |
Impdh2 |
inosine monophosphate dehydrogenase 2 |
increases expression |
ISO |
microcystin RR results in increased expression of IMPDH2 protein |
CTD |
PMID:19111056 |
|
NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
|
|
G |
Kpna4 |
karyopherin subunit alpha 4 |
increases expression |
ISO |
microcystin RR results in increased expression of KPNA4 protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:165,684,345...165,739,874
Ensembl chr 2:165,684,345...165,739,874
|
|
G |
Krt10 |
keratin 10 |
increases expression decreases expression |
ISO |
microcystin RR results in increased expression of KRT10 protein microcystin RR results in decreased expression of KRT10 protein |
CTD |
PMID:19111056 |
|
NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
|
|
G |
Krt2 |
keratin 2 |
decreases expression |
ISO |
microcystin RR results in decreased expression of KRT2 protein |
CTD |
PMID:19111056 |
|
NCBI chr 7:143,412,858...143,420,463
Ensembl chr 7:143,412,858...143,420,027
|
|
G |
Ldhc |
lactate dehydrogenase C |
decreases expression |
ISO |
microcystin RR results in decreased expression of LDHC protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
|
|
G |
Lgals1 |
galectin 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of LGALS1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
|
|
G |
Lmna |
lamin A/C |
increases expression |
ISO |
microcystin RR results in increased expression of LMNA protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
|
|
G |
Macf1 |
microtubule-actin crosslinking factor 1 |
increases expression |
ISO |
microcystin RR results in increased expression of MACF1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:141,039,455...141,363,524
Ensembl chr 5:141,039,468...141,363,524
|
|
G |
Mcm7 |
minichromosome maintenance complex component 7 |
decreases expression increases expression |
ISO |
microcystin RR results in decreased expression of MCM7 protein microcystin RR results in increased expression of MCM7 protein |
CTD |
PMID:19111056 |
|
NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
|
|
G |
Mrps22 |
mitochondrial ribosomal protein S22 |
decreases expression |
ISO |
microcystin RR results in decreased expression of MRPS22 protein |
CTD |
PMID:19111056 |
|
NCBI chr 8:106,604,421...106,617,591
Ensembl chr 8:106,604,379...106,617,597
|
|
G |
Napg |
NSF attachment protein gamma |
decreases expression |
ISO |
microcystin RR results in decreased expression of NAPG protein |
CTD |
PMID:19111056 |
|
NCBI chr18:58,325,319...58,344,071
Ensembl chr18:58,325,319...58,344,070
|
|
G |
Naxe |
NAD(P)HX epimerase |
decreases expression |
ISO |
microcystin RR results in decreased expression of NAXE protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:187,424,319...187,426,410
Ensembl chr 2:187,424,327...187,426,375
|
|
G |
Nit2 |
nitrilase family, member 2 |
decreases expression |
ISO |
microcystin RR results in decreased expression of NIT2 protein |
CTD |
PMID:19111056 |
|
NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
|
|
G |
Nutf2 |
nuclear transport factor 2 |
decreases expression |
ISO |
microcystin RR results in decreased expression of NUTF2 protein |
CTD |
PMID:19111056 |
|
NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189
|
|
G |
Pdcd6 |
programmed cell death 6 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PDCD6 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849
|
|
G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
increases expression |
ISO |
microcystin RR results in increased expression of PDIA3 protein |
CTD |
PMID:19111056 |
|
NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
|
|
G |
Pgam1 |
phosphoglycerate mutase 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PGAM1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
|
|
G |
Phpt1 |
phosphohistidine phosphatase 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PHPT1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 3:2,797,037...2,798,436
Ensembl chr 3:2,796,997...2,798,470
|
|
G |
Pmpcb |
peptidase, mitochondrial processing subunit beta |
increases expression |
ISO |
microcystin RR results in increased expression of PMPCB protein |
CTD |
PMID:19111056 |
|
NCBI chr 4:9,908,838...9,921,615
Ensembl chr 4:9,908,831...9,921,610
|
|
G |
Pnp |
purine nucleoside phosphorylase |
decreases expression |
ISO |
microcystin RR results in decreased expression of PNP protein |
CTD |
PMID:19111056 |
|
NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350
|
|
G |
Ppa1 |
inorganic pyrophosphatase 1 |
increases expression decreases expression |
ISO |
microcystin RR results in increased expression of PPA1 protein microcystin RR results in decreased expression of PPA1 protein |
CTD |
PMID:19111056 |
|
NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
|
|
G |
Ppp2r1a |
protein phosphatase 2 scaffold subunit A alpha |
increases expression |
ISO |
microcystin RR results in increased expression of PPP2R1A protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
|
|
G |
Ppp2r5b |
protein phosphatase 2, regulatory subunit B', beta |
increases expression |
ISO |
microcystin RR results in increased expression of PPP2R5B protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:221,597,294...221,605,467
Ensembl chr 1:221,597,296...221,605,400
|
|
G |
Prps2 |
phosphoribosyl pyrophosphate synthetase 2 |
increases expression decreases expression |
ISO |
microcystin RR results in increased expression of PRPS2 protein microcystin RR results in decreased expression of PRPS2 protein |
CTD |
PMID:19111056 |
|
NCBI chr X:28,435,275...28,472,882
Ensembl chr X:28,435,507...28,472,880
|
|
G |
Psma1 |
proteasome 20S subunit alpha 1 |
increases expression |
ISO |
microcystin RR results in increased expression of PSMA1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
|
|
G |
Psmb2 |
proteasome 20S subunit beta 2 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PSMB2 protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
|
|
G |
Psmb3 |
proteasome 20S subunit beta 3 |
increases expression |
ISO |
microcystin RR results in increased expression of PSMB3 protein |
CTD |
PMID:19111056 |
|
NCBI chr10:85,646,646...85,653,729
Ensembl chr10:85,646,633...85,653,729
|
|
G |
Psmb4 |
proteasome 20S subunit beta 4 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PSMB4 protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:196,043,546...196,046,320
Ensembl chr 2:196,043,618...196,046,311
|
|
G |
Psmb6 |
proteasome 20S subunit beta 6 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PSMB6 protein |
CTD |
PMID:19111056 |
|
NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
|
|
G |
Psmb9 |
proteasome 20S subunit beta 9 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PSMB9 protein |
CTD |
PMID:19111056 |
|
NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
|
|
G |
Psmd10 |
proteasome 26S subunit, non-ATPase 10 |
decreases expression |
ISO |
microcystin RR results in decreased expression of PSMD10 protein |
CTD |
PMID:19111056 |
|
NCBI chr X:112,323,188...112,328,642
Ensembl chr X:112,323,187...112,328,642
|
|
G |
Psme1 |
proteasome activator subunit 1 |
increases expression |
ISO |
microcystin RR results in increased expression of PSME1 protein |
CTD |
PMID:19111056 |
|
NCBI chr15:34,256,071...34,258,947
Ensembl chr15:34,256,071...34,258,947
|
|
G |
Rab14 |
RAB14, member RAS oncogene family |
increases expression |
ISO |
microcystin RR results in increased expression of RAB14 protein |
CTD |
PMID:19111056 |
|
NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
|
|
G |
Rfc5 |
replication factor C subunit 5 |
increases expression |
ISO |
microcystin RR results in increased expression of RFC5 protein |
CTD |
PMID:19111056 |
|
NCBI chr12:44,931,494...44,941,051
Ensembl chr12:44,931,494...44,941,324
|
|
G |
Septin11 |
septin 11 |
increases expression |
ISO |
microcystin RR results in increased expression of SEPTIN11 protein |
CTD |
PMID:19111056 |
|
NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
|
|
G |
Septin2 |
septin 2 |
increases expression |
ISO |
microcystin RR results in increased expression of SEPTIN2 protein |
CTD |
PMID:19111056 |
|
NCBI chr 9:100,624,876...100,658,053
Ensembl chr 9:100,624,876...100,658,050
|
|
G |
Serpinb5 |
serpin family B member 5 |
decreases expression |
ISO |
microcystin RR results in decreased expression of SERPINB5 protein |
CTD |
PMID:19111056 |
|
NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
|
|
G |
Sod1 |
superoxide dismutase 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of SOD1 protein |
CTD |
PMID:19111056 |
|
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
|
|
G |
Taldo1 |
transaldolase 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of TALDO1 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
|
|
G |
Tbca |
tubulin folding cofactor A |
decreases expression |
ISO |
microcystin RR results in decreased expression of TBCA protein |
CTD |
PMID:19111056 |
|
NCBI chr 2:24,449,498...24,505,351
Ensembl chr 2:24,449,485...24,505,334
|
|
G |
Tbcb |
tubulin folding cofactor B |
increases expression |
ISO |
microcystin RR results in increased expression of TBCB protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:88,680,936...88,686,785
Ensembl chr 1:88,680,856...88,686,615
|
|
G |
Timm50 |
translocase of inner mitochondrial membrane 50 |
decreases expression |
ISO |
microcystin RR results in decreased expression of TIMM50 protein |
CTD |
PMID:19111056 |
|
NCBI chr 1:85,470,810...85,480,813
Ensembl chr 1:85,470,831...85,480,407
|
|
G |
Tnfrsf25 |
TNF receptor superfamily member 25 |
decreases expression |
ISO |
microcystin RR results in decreased expression of TNFRSF25 protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
|
|
G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
microcystin RR results in increased expression of TP53 protein microcystin RR results in increased expression of TRP53 protein |
CTD |
PMID:19111056 PMID:20196164 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
G |
Tpm4 |
tropomyosin 4 |
decreases expression |
ISO |
microcystin RR results in decreased expression of TPM4 protein |
CTD |
PMID:19111056 |
|
NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
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|
G |
Trpc7 |
transient receptor potential cation channel, subfamily C, member 7 |
increases expression |
ISO |
microcystin RR results in increased expression of TRPC7 protein |
CTD |
PMID:19111056 |
|
NCBI chr17:8,134,267...8,280,360
Ensembl chr17:8,135,251...8,279,515
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|
G |
Txn1 |
thioredoxin 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of TXN protein |
CTD |
PMID:19111056 |
|
NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
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G |
Txnl1 |
thioredoxin-like 1 |
decreases expression |
ISO |
microcystin RR results in decreased expression of TXNL1 protein |
CTD |
PMID:19111056 |
|
NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
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|
G |
Ufd1 |
ubiquitin recognition factor in ER associated degradation 1 |
increases expression |
ISO |
microcystin RR results in increased expression of UFD1 protein |
CTD |
PMID:19111056 |
|
NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
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G |
Vcl |
vinculin |
decreases expression increases expression |
ISO |
microcystin RR results in decreased expression of VCL protein microcystin RR results in increased expression of VCL protein |
CTD |
PMID:19111056 |
|
NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
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|
G |
Ywhag |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma |
decreases expression |
ISO |
microcystin RR results in decreased expression of YWHAG protein |
CTD |
PMID:19111056 |
|
NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
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G |
Zfp951 |
zinc finger protein 951 |
increases expression |
ISO |
microcystin RR results in increased expression of ZNF57 protein |
CTD |
PMID:19111056 |
|
NCBI chr14:6,280,767...6,284,145
Ensembl chr14:6,281,336...6,284,145 Ensembl chr14:6,281,336...6,284,145
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G |
Abca8 |
ATP binding cassette subfamily A member 8 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ABCA8B mRNA |
CTD |
PMID:17654400 |
|
NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
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|
G |
Abcb10 |
ATP binding cassette subfamily B member 10 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ABCB10 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr19:56,742,809...56,772,904
Ensembl chr19:56,742,835...56,772,904
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|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ABCB1A mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases expression increases export multiple interactions |
ISO |
cyanoginosin LR results in increased expression of ABCC2 mRNA ABCC2 protein results in increased export of cyanoginosin LR cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:17654400 PMID:31348918 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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|
G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ABCC5 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
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G |
Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACAA1 protein |
CTD |
PMID:26984711 |
|
NCBI chr 8:127,836,235...127,845,296
|
|
G |
Acaca |
acetyl-CoA carboxylase alpha |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACACA protein |
CTD |
PMID:26984711 |
|
NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
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|
G |
Acad10 |
acyl-CoA dehydrogenase family, member 10 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACAD10 protein |
CTD |
PMID:26984711 |
|
NCBI chr12:40,417,918...40,460,562
Ensembl chr12:40,417,944...40,460,561
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|
G |
Acad11 |
acyl-CoA dehydrogenase family, member 11 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACAD11 protein |
CTD |
PMID:26984711 |
|
NCBI chr 8:112,594,758...112,676,275
Ensembl chr 8:112,594,691...112,676,280
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|
G |
Acadl |
acyl-CoA dehydrogenase, long chain |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACADL protein |
CTD |
PMID:26984711 |
|
NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
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|
G |
Acadm |
acyl-CoA dehydrogenase medium chain |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACADM protein |
CTD |
PMID:26984711 |
|
NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
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|
G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACADVL protein |
CTD |
PMID:26984711 |
|
NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
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|
G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
affects expression |
ISO |
cyanoginosin LR affects the expression of ACAT2 protein |
CTD |
PMID:26984711 |
|
NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
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|
G |
Acox3 |
acyl-CoA oxidase 3, pristanoyl |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ACOX3 protein |
CTD |
PMID:26984711 |
|
NCBI chr14:80,313,202...80,358,115
Ensembl chr14:80,314,431...80,355,420
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|
G |
Actb |
actin, beta |
decreases expression |
ISO EXP |
cyanoginosin LR results in decreased expression of ACTB mRNA |
CTD |
PMID:17383702 PMID:23342045 |
|
NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
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|
G |
Afm |
afamin |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of AFM mRNA |
CTD |
PMID:17654400 |
|
NCBI chr14:19,078,678...19,132,212
Ensembl chr14:19,078,680...19,132,208
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|
G |
Akr1b1 |
aldo-keto reductase family 1 member B |
increases expression |
ISO |
cyanoginosin LR results in increased expression of AKR1B3 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
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|
G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation decreases expression multiple interactions |
ISO |
cyanoginosin LR results in increased phosphorylation of AKT1 protein cyanoginosin LR results in decreased expression of AKT1 mRNA; cyanoginosin LR results in decreased expression of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:26506538 PMID:29777831 PMID:31714646 PMID:32073747 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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|
G |
Akt3 |
AKT serine/threonine kinase 3 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of AKT3 mRNA; cyanoginosin LR results in decreased expression of AKT3 protein |
CTD |
PMID:28414124 PMID:29518473 |
|
NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
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|
G |
Alb |
albumin |
decreases expression increases secretion |
ISO |
cyanoginosin LR results in decreased expression of ALB mRNA; cyanoginosin LR results in decreased expression of ALB protein cyanoginosin LR results in increased secretion of ALB protein |
CTD |
PMID:17654400 PMID:17654404 PMID:26984711 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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|
G |
Aldh1l1 |
aldehyde dehydrogenase 1 family, member L1 |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of ALDH1L1 protein |
CTD |
PMID:18000846 |
|
NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
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|
G |
Alpi |
alkaline phosphatase, intestinal |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ALPI mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
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|
G |
Alyref |
Aly/REF export factor |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of THOC4 protein |
CTD |
PMID:26984711 |
|
NCBI chr10:109,768,593...109,774,639
Ensembl chr10:109,770,876...109,774,639
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|
G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ANXA2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
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|
G |
Anxa4 |
annexin A4 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ANXA4 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
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|
G |
Anxa5 |
annexin A5 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ANXA5 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
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|
G |
Anxa7 |
annexin A7 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ANXA7 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
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|
G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of APEX1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
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|
G |
Apoa1 |
apolipoprotein A1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of APOA1 protein |
CTD |
PMID:26984711 |
|
NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
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|
G |
Apob |
apolipoprotein B |
affects expression |
ISO |
cyanoginosin LR affects the expression of APOB protein |
CTD |
PMID:26984711 |
|
NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
|
|
G |
Apoc3 |
apolipoprotein C3 |
affects expression |
ISO |
cyanoginosin LR affects the expression of APOC3 protein |
CTD |
PMID:26984711 |
|
NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
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|
G |
Apoe |
apolipoprotein E |
increases expression |
ISO |
cyanoginosin LR results in increased expression of APOE protein |
CTD |
PMID:26984711 |
|
NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
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|
G |
Ar |
androgen receptor |
affects expression |
ISO |
cyanoginosin LR affects the expression of AR mRNA; cyanoginosin LR affects the expression of AR protein |
CTD |
PMID:28189720 |
|
NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
|
|
G |
Arhgef2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
|
|
G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ASNS mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
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|
G |
Ass1 |
argininosuccinate synthase 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ASS1 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
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|
G |
Atf2 |
activating transcription factor 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ATF2 protein modified form |
CTD |
PMID:27393157 |
|
NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
|
|
G |
Atox1 |
antioxidant 1 copper chaperone |
increases expression |
ISO |
cyanoginosin LR results in increased expression of ATOX1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
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|
G |
Bad |
BCL2-associated agonist of cell death |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of BAD protein |
CTD |
PMID:26506538 PMID:27352821 |
|
NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
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|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO EXP |
cyanoginosin LR results in increased expression of BAX mRNA; cyanoginosin LR results in increased expression of BAX protein |
CTD |
PMID:17654400 PMID:18214937 PMID:22539157 PMID:23891578 PMID:25410294 PMID:28414124 PMID:31157505 PMID:32142839 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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|
G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions increases expression |
EXP |
pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of BBC3 protein] |
CTD |
PMID:31157505 |
|
NCBI chr 1:78,261,491...78,267,802
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression increases phosphorylation multiple interactions |
ISO EXP |
cyanoginosin LR results in increased expression of BCL2 cyanoginosin LR results in decreased expression of BCL2 protein cyanoginosin LR results in increased phosphorylation of BCL2 protein cyanoginosin LR results in increased expression of and results in increased phosphorylation of BCL2 protein Buthionine Sulfoximine promotes the reaction [cyanoginosin LR results in decreased expression of BCL2 protein] |
CTD |
PMID:16624733 PMID:18214937 PMID:23891578 PMID:25410294 PMID:26506538 PMID:27352821 PMID:32142839 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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|
G |
Bcl2l11 |
BCL2 like 11 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of BCL2L11 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of BIRC3 protein |
CTD |
PMID:22539157 |
|
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
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|
G |
Blvrb |
biliverdin reductase B |
increases expression |
ISO |
cyanoginosin LR results in increased expression of BLVRB mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
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|
G |
Bmp5 |
bone morphogenetic protein 5 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of BMP5 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
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|
G |
Bsg |
basigin (Ok blood group) |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of BSG mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
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|
G |
C9 |
complement C9 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of C9 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
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|
G |
Cables1 |
Cdk5 and Abl enzyme substrate 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CABLES1 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
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|
G |
Calm2 |
calmodulin 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CALM2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
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|
G |
Calm3 |
calmodulin 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CALM3 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
|
|
G |
Camk1 |
calcium/calmodulin-dependent protein kinase I |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CAMK1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
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|
G |
Capn2 |
calpain 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CAPN2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
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|
G |
Capns1 |
calpain, small subunit 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CAPNS1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:91,058,528...91,064,880
|
|
G |
Capzb |
capping actin protein of muscle Z-line subunit beta |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CAPZB mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
|
|
G |
Casp3 |
caspase 3 |
increases activity increases cleavage multiple interactions increases expression |
ISO EXP |
cyanoginosin LR results in increased activity of CASP3 protein cyanoginosin LR results in increased cleavage of CASP3 protein pifithrin inhibits the reaction [cyanoginosin LR results in increased cleavage of CASP3 protein] cyanoginosin LR results in increased expression of CASP3 mRNA cyanoginosin LR results in increased expression of CASP3 mRNA; cyanoginosin LR results in increased expression of CASP3 protein sulforafan inhibits the reaction [cyanoginosin LR results in increased activity of CASP3 protein] |
CTD |
PMID:21684301 PMID:22539157 PMID:23454832 PMID:23891578 PMID:28414124 PMID:31157505 PMID:32142839 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp8 |
caspase 8 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CASP8 mRNA; cyanoginosin LR results in increased expression of CASP8 protein |
CTD |
PMID:23454832 PMID:23891578 |
|
NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
|
|
G |
Casp9 |
caspase 9 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CASP9 protein |
CTD |
PMID:23454832 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Cast |
calpastatin |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CAST mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
|
|
G |
Cat |
catalase |
decreases expression multiple interactions decreases activity increases activity |
ISO |
cyanoginosin LR results in decreased expression of CAT mRNA GCLC protein inhibits the reaction [cyanoginosin LR results in decreased activity of CAT protein] cyanoginosin LR results in increased activity of CAT protein Quercetin inhibits the reaction [cyanoginosin LR results in increased activity of CAT protein] |
CTD |
PMID:17383702 PMID:17654400 PMID:17696131 PMID:30940545 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Cbr1 |
carbonyl reductase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CBR1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
|
|
G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CBR3 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
|
|
G |
Ccdc180 |
coiled-coil domain containing 180 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CCDC180 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 5:61,467,799...61,542,675
Ensembl chr 5:61,474,000...61,542,653
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|
G |
Ccnd1 |
cyclin D1 |
increases expression decreases expression |
ISO |
cyanoginosin LR results in increased expression of CCND1 mRNA cyanoginosin LR results in decreased expression of CCND1 mRNA; cyanoginosin LR results in decreased expression of CCND1 protein |
CTD |
PMID:17654400 PMID:28414124 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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|
G |
Ccnf |
cyclin F |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CCNF mRNA |
CTD |
PMID:17654400 |
|
NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
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G |
Ccng1 |
cyclin G1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CCNG1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
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|
G |
Cd2ap |
CD2-associated protein |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CD2AP mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
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|
G |
Cdc42 |
cell division cycle 42 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CDC42 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
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|
G |
Cdh1 |
cadherin 1 |
decreases expression multiple interactions |
ISO |
cyanoginosin LR results in decreased expression of CDH1 mRNA; cyanoginosin LR results in decreased expression of CDH1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in decreased expression of CDH1 protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in decreased expression of CDH1 protein] |
CTD |
PMID:27856280 |
|
NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
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|
G |
Cdk1 |
cyclin-dependent kinase 1 |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of CDK1 protein |
CTD |
PMID:26506538 |
|
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
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|
G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CDK4 mRNA; cyanoginosin LR results in decreased expression of CDK4 protein |
CTD |
PMID:28414124 |
|
NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
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|
G |
Cdk6 |
cyclin-dependent kinase 6 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CDK6 mRNA; cyanoginosin LR results in decreased expression of CDK6 protein |
CTD |
PMID:28414124 |
|
NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
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|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO EXP |
cyanoginosin LR results in increased expression of CDKN1A protein pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of CDKN1A protein] cyanoginosin LR results in increased expression of CDKN1A mRNA |
CTD |
PMID:17654400 PMID:20421190 PMID:31157505 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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|
G |
Cebpd |
CCAAT/enhancer binding protein delta |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CEBPD mRNA |
CTD |
PMID:17383702 |
|
NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
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|
G |
Coro1c |
coronin 1C |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CORO1C mRNA |
CTD |
PMID:17654400 |
|
NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052
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|
G |
Creb3 |
cAMP responsive element binding protein 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CREB3 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188
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|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions decreases expression |
ISO |
cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA] cyanoginosin LR results in decreased expression of CSF2 mRNA; cyanoginosin LR results in decreased expression of CSF2 protein |
CTD |
PMID:15712326 PMID:23454832 |
|
NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
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|
G |
Cspg4 |
chondroitin sulfate proteoglycan 4 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CSPG4 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
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|
G |
Cstb |
cystatin B |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CSTB mRNA |
CTD |
PMID:17654400 |
|
NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
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|
G |
Ctnnb1 |
catenin beta 1 |
increases ubiquitination |
ISO |
cyanoginosin LR results in increased ubiquitination of CTNNB1 protein |
CTD |
PMID:20421190 |
|
NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
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|
G |
Ctsl |
cathepsin L |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CTSL mRNA |
CTD |
PMID:17654400 |
|
NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
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|
G |
Ctsz |
cathepsin Z |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CTSZ mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 3:172,527,107...172,537,877
Ensembl chr 3:172,527,107...172,537,877
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|
G |
Cttn |
cortactin |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CTTN mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:217,602,698...217,638,196 NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152 Ensembl chr 1:217,602,698...217,638,152
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|
G |
Cybb |
cytochrome b-245 beta chain |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CYBB mRNA |
CTD |
PMID:17654400 |
|
NCBI chr X:14,578,330...14,610,049
Ensembl chr X:14,578,264...14,612,547
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|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
affects expression |
ISO |
cyanoginosin LR affects the expression of CYP19A1 protein |
CTD |
PMID:28189720 |
|
NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
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|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of CYP1A2 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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|
G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CYP26A1 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
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|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions affects expression increases expression |
ISO |
allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein]; Thioctic Acid affects the reaction [cyanoginosin LR affects the expression of CYP2E1 protein] cyanoginosin LR results in increased expression of CYP2E1 mRNA; cyanoginosin LR results in increased expression of CYP2E1 protein |
CTD |
PMID:21684301 PMID:32061150 |
|
NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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|
G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of CYP8B1 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
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|
G |
Dap3 |
death associated protein 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DAP3 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725
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|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression affects expression |
ISO |
cyanoginosin LR results in increased expression of DDIT3 mRNA cyanoginosin LR affects the expression of DDIT3 protein |
CTD |
PMID:17654400 PMID:18214937 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
|
|
G |
Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DDIT4 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
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|
G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DDIT4L mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131
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|
G |
Decr2 |
2,4-dienoyl-CoA reductase 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of DECR2 mRNA; cyanoginosin LR results in decreased expression of DECR2 protein |
CTD |
PMID:17383702 PMID:26984711 |
|
NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
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|
G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DGAT1 protein |
CTD |
PMID:26984711 |
|
NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
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|
G |
Dio2 |
iodothyronine deiodinase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DIO2 protein |
CTD |
PMID:25497113 |
|
NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
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|
G |
Dnmt3a |
DNA methyltransferase 3 alpha |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DNMT3A mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
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|
G |
Dnmt3b |
DNA methyltransferase 3 beta |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DNMT3B mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
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|
G |
Dusp10 |
dual specificity phosphatase 10 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of DUSP10 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
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|
G |
Eef1d |
eukaryotic translation elongation factor 1 delta |
increases expression |
ISO |
cyanoginosin LR results in increased expression of EEF1D protein |
CTD |
PMID:26984711 |
|
NCBI chr 7:116,928,264...116,942,981
Ensembl chr 7:116,928,265...116,936,674
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|
G |
Egfr |
epidermal growth factor receptor |
increases expression decreases methylation |
ISO |
cyanoginosin LR results in increased expression of EGFR mRNA cyanoginosin LR results in decreased methylation of EGFR gene |
CTD |
PMID:29518473 |
|
NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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|
G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of EGR1 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
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|
G |
Eif4a3 |
eukaryotic translation initiation factor 4A3 |
affects expression |
ISO |
cyanoginosin LR affects the expression of EIF4A3 protein |
CTD |
PMID:26984711 |
|
NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
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|
G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:26506538 |
|
NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
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|
G |
Epo |
erythropoietin |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of EPO mRNA; cyanoginosin LR results in decreased expression of EPO protein |
CTD |
PMID:23454832 |
|
NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
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|
G |
Esr1 |
estrogen receptor 1 |
increases expression affects expression |
ISO |
cyanoginosin LR results in increased expression of ESR1 protein cyanoginosin LR affects the expression of ESR1 mRNA |
CTD |
PMID:28189720 |
|
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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|
G |
Etv5 |
ETS variant transcription factor 5 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of ETV5 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
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G |
Ezr |
ezrin |
increases expression increases phosphorylation multiple interactions |
EXP ISO |
cyanoginosin LR results in increased expression of EZR mRNA cyanoginosin LR results in increased phosphorylation of EZR protein [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of EZR protein modified form; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of EZR protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of EZR protein] |
CTD |
PMID:23342045 PMID:24677693 PMID:27352821 PMID:27393157 PMID:29984889 |
|
NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
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|
G |
Fabp1 |
fatty acid binding protein 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of FABP1 protein |
CTD |
PMID:26984711 |
|
NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
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|
G |
Fabp2 |
fatty acid binding protein 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of FABP2 protein |
CTD |
PMID:26984711 |
|
NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
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|
G |
Fads1 |
fatty acid desaturase 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of FADS1 protein |
CTD |
PMID:26984711 |
|
NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
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|
G |
Fads2 |
fatty acid desaturase 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of FADS2 protein |
CTD |
PMID:26984711 |
|
NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
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|
G |
Fasn |
fatty acid synthase |
increases expression decreases expression |
ISO |
cyanoginosin LR results in increased expression of FASN mRNA cyanoginosin LR results in decreased expression of FASN protein |
CTD |
PMID:25497113 PMID:26984711 |
|
NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
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|
G |
Fgf13 |
fibroblast growth factor 13 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of FGF13 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr X:142,053,648...142,589,274
Ensembl chr X:142,053,654...142,248,369
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|
G |
Fgf21 |
fibroblast growth factor 21 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of FGF21 mRNA |
CTD |
PMID:25497113 |
|
NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
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|
G |
Fhdc1 |
FH2 domain containing 1 |
increases methylation decreases expression |
ISO |
cyanoginosin LR results in increased methylation of FHDC1 gene cyanoginosin LR results in decreased expression of FHDC1 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 2:183,450,608...183,487,820
Ensembl chr 2:183,450,619...183,487,820
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|
G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of FN1 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
cyanoginosin LR results in increased expression of FOS mRNA cyanoginosin LR results in increased expression of FOS mRNA; cyanoginosin LR results in increased expression of FOS protein |
CTD |
PMID:23891578 PMID:28062358 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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|
G |
Ftl1 |
ferritin light chain 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of FTL1 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
|
|
G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of G6PC1 mRNA |
CTD |
PMID:17654400 PMID:25497113 |
|
NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GADD45A mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
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|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of GADD45G mRNA |
CTD |
PMID:17383702 |
|
NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
|
|
G |
Gas1 |
growth arrest-specific 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of GAS1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
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|
G |
Gbp5 |
guanylate binding protein 5 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GBP5 mRNA |
CTD |
PMID:29518473 |
|
NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
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|
G |
Gck |
glucokinase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GCK mRNA |
CTD |
PMID:17654400 PMID:25497113 |
|
NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
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|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions decreases expression |
ISO |
cyanoginosin LR results in increased expression of GCLC mRNA cyanoginosin LR results in decreased expression of and results in increased phosphorylation of GCLC protein; GCLC protein inhibits the reaction [cyanoginosin LR results in decreased activity of CAT protein] cyanoginosin LR results in decreased expression of GCLC mRNA |
CTD |
PMID:17654400 PMID:30940545 |
|
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
|
|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GGT1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
|
|
G |
Gipc2 |
GIPC PDZ domain containing family, member 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GIPC2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:257,293,161...257,377,982
Ensembl chr 2:257,293,167...257,376,756
|
|
G |
Glrx3 |
glutaredoxin 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GLRX3 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
|
|
G |
Gna13 |
G protein subunit alpha 13 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GNA13 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr10:97,647,196...97,680,030
Ensembl chr10:97,647,111...97,684,730
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G |
Gnb1 |
G protein subunit beta 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GNB1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GPAM protein |
CTD |
PMID:26984711 |
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NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
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G |
Gpx1 |
glutathione peroxidase 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of GPX1 protein |
CTD |
PMID:30076769 |
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NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
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G |
Gpx2 |
glutathione peroxidase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GPX2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
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G |
Gpx3 |
glutathione peroxidase 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GPX3 mRNA |
CTD |
PMID:17654400 |
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NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
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G |
Gpx4 |
glutathione peroxidase 4 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GPX4 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
multiple interactions increases phosphorylation |
ISO |
cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3A protein]; cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3A protein; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3A protein] cyanoginosin LR results in increased phosphorylation of GSK3A protein |
CTD |
PMID:28984034 PMID:31714646 PMID:32073747 |
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NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation multiple interactions |
ISO |
cyanoginosin LR results in increased phosphorylation of GSK3B protein cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3B protein]; cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein] |
CTD |
PMID:20421190 PMID:28984034 PMID:32073747 |
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NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
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G |
Gsn |
gelsolin |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSN mRNA |
CTD |
PMID:17654400 |
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NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
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G |
Gsr |
glutathione-disulfide reductase |
increases expression decreases activity multiple interactions increases activity |
ISO EXP |
cyanoginosin LR results in increased expression of GSR mRNA cyanoginosin LR results in decreased activity of GSR protein Thioctic Acid inhibits the reaction [cyanoginosin LR results in decreased activity of GSR protein] [cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased activity of GSR protein cyanoginosin LR results in increased activity of GSR protein |
CTD |
PMID:17654400 PMID:25410294 PMID:32061150 |
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NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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G |
Gss |
glutathione synthetase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSS mRNA |
CTD |
PMID:17654400 |
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NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
GSTA1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR |
CTD |
PMID:21504230 |
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NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSTA2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 8:85,640,081...85,645,621
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of GSTA3 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
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G |
Gsta6 |
glutathione S-transferase alpha 6 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSTA2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
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G |
Gstk1 |
glutathione S-transferase kappa 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of GSTK1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
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G |
Gstm1 |
glutathione S-transferase mu 1 |
multiple interactions increases expression decreases expression |
ISO |
GSTM1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR cyanoginosin LR results in increased expression of GSTM1 mRNA; cyanoginosin LR results in increased expression of GSTM5 mRNA cyanoginosin LR results in decreased expression of GSTM1 mRNA |
CTD |
PMID:17383702 PMID:17654400 PMID:21504230 |
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NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
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G |
Gstm2 |
glutathione S-transferase mu 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSTM2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
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G |
Gstm4 |
glutathione S-transferase mu 4 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSTM4 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of GSTM3 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
GSTP1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR |
CTD |
PMID:21504230 |
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NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
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G |
Gstt1 |
glutathione S-transferase theta 1 |
multiple interactions |
ISO |
GSTT1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR |
CTD |
PMID:21504230 |
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NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
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G |
Gtpbp4 |
GTP binding protein 4 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of GTPBP4 protein |
CTD |
PMID:26984711 |
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NCBI chr17:63,111,086...63,145,618
Ensembl chr17:63,110,254...63,145,577
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G |
Gys1 |
glycogen synthase 1 |
multiple interactions |
ISO |
cyanoginosin LR results in increased expression of and results in increased phosphorylation of and results in decreased activity of GYS1 protein cyanoginosin LR inhibits the reaction [INS protein results in decreased phosphorylation of and results in increased activity of GYS1 protein]; cyanoginosin LR results in increased expression of and results in increased phosphorylation of and results in decreased activity of GYS1 protein |
CTD |
PMID:28984034 |
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NCBI chr 1:101,427,195...101,447,092
Ensembl chr 1:101,427,195...101,447,092
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G |
H2bc1 |
H2B clustered histone 1 |
decreases expression |
EXP |
cyanoginosin LR results in decreased expression of H2BC1 mRNA |
CTD |
PMID:24025782 |
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NCBI chr17:43,423,111...43,423,580
Ensembl chr17:43,423,111...43,423,580
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G |
Hadh |
hydroxyacyl-CoA dehydrogenase |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of HADH protein |
CTD |
PMID:26984711 |
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NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
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G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of HADHB protein |
CTD |
PMID:26984711 |
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NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
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G |
Hephl1 |
hephaestin-like 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of HEPHL1 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 8:13,614,800...13,680,870
Ensembl chr 8:13,614,800...13,680,870
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G |
Hk2 |
hexokinase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of HK2 mRNA |
CTD |
PMID:17654400 PMID:25497113 |
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NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of HMGCR mRNA |
CTD |
PMID:25497113 |
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NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
[cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; cyanoginosin LR promotes the reaction [sulforafan results in increased expression of HMOX1 protein]; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of HMOX1 protein] cyanoginosin LR results in increased expression of HMOX1 mRNA; cyanoginosin LR results in increased expression of HMOX1 protein |
CTD |
PMID:20600217 PMID:20722399 |
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NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of HNF4A mRNA |
CTD |
PMID:25497113 |
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NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
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G |
Hpx |
hemopexin |
increases expression |
ISO |
cyanoginosin LR results in increased expression of HPX protein |
CTD |
PMID:26984711 |
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NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of HSPA8 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
increases expression increases phosphorylation multiple interactions |
ISO EXP |
cyanoginosin LR results in increased expression of HSPB1 mRNA cyanoginosin LR results in increased phosphorylation of HSPB1 protein SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of HSPB1 protein] |
CTD |
PMID:17654400 PMID:22000993 PMID:27393157 |
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NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of IDH1 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA] |
CTD |
PMID:15712326 |
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NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
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G |
Igbp1 |
immunoglobulin binding protein 1 |
multiple interactions increases response to substance affects response to substance |
ISO |
[IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of PPP2CA protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of VASP protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of EZR protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of PPP2CA protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK1 protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK3 protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK9 protein; cyanoginosin LR inhibits the reaction [IGBP1 protein binds to PPP2CA protein]; cyanoginosin LR inhibits the reaction [PPP2CA protein binds to IGBP1 protein] IGBP1 protein affects the susceptibility to cyanoginosin LR |
CTD |
PMID:26784437 PMID:27393157 PMID:29984889 |
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NCBI chr X:70,322,764...70,345,005
Ensembl chr X:70,322,755...70,345,005
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of IGFBP1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
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G |
Igkc |
immunoglobulin kappa constant |
increases expression |
ISO |
cyanoginosin LR results in increased expression of IGKC protein |
CTD |
PMID:26984711 |
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G |
Il10 |
interleukin 10 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of IL10 protein |
CTD |
PMID:26984711 |
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NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO |
cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] cyanoginosin LR results in increased expression of IL1B protein |
CTD |
PMID:15712326 PMID:26984711 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il2 |
interleukin 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of IL2 protein |
CTD |
PMID:15369846 |
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NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
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G |
Il3 |
interleukin 3 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of IL3 mRNA; cyanoginosin LR results in decreased expression of IL3 protein |
CTD |
PMID:23454832 |
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NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO |
cyanoginosin LR results in increased expression of IL6 protein cyanoginosin LR promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL6 protein]; cyanoginosin LR results in increased expression of and results in increased secretion of IL6 protein |
CTD |
PMID:15369846 PMID:23970801 PMID:26984711 PMID:28189720 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Inmt |
indolethylamine N-methyltransferase |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of INMT protein |
CTD |
PMID:26984711 |
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NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
cyanoginosin LR inhibits the reaction [INS protein results in decreased phosphorylation of and results in increased activity of GYS1 protein]; cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]; cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3A protein]; cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3B protein]; cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]; INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3A protein]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]] |
CTD |
PMID:28984034 |
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NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of INSIG1 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
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G |
Ints2 |
integrator complex subunit 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of INTS2 mRNA |
CTD |
PMID:29518473 |
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NCBI chr10:73,632,805...73,690,952
Ensembl chr10:73,634,255...73,690,887
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G |
Irs1 |
insulin receptor substrate 1 |
increases phosphorylation decreases expression decreases phosphorylation multiple interactions |
ISO |
cyanoginosin LR results in increased phosphorylation of IRS1 protein cyanoginosin LR results in decreased expression of IRS1 mRNA cyanoginosin LR results in decreased phosphorylation of IRS1 protein cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Sirolimus inhibits the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]] cyanoginosin LR results in decreased expression of and results in increased phosphorylation of IRS1 protein |
CTD |
PMID:28984034 PMID:29777831 PMID:31714646 PMID:32073747 |
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NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
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G |
Irs2 |
insulin receptor substrate 2 |
decreases expression decreases phosphorylation |
ISO |
cyanoginosin LR results in decreased expression of IRS2 mRNA; cyanoginosin LR results in decreased expression of IRS2 protein cyanoginosin LR results in decreased phosphorylation of IRS2 protein |
CTD |
PMID:29777831 |
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NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
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G |
Jak1 |
Janus kinase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of JAK1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression increases phosphorylation |
ISO |
cyanoginosin LR results in increased expression of JUN mRNA cyanoginosin LR results in increased expression of JUN mRNA; cyanoginosin LR results in increased expression of JUN protein cyanoginosin LR results in increased phosphorylation of JUN protein |
CTD |
PMID:17654400 PMID:23891578 PMID:26506538 PMID:28062358 |
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NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
cyanoginosin LR results in increased expression of JUND mRNA |
CTD |
PMID:17654400 |
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NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
affects binding |
ISO |
cyanoginosin LR binds to KEAP1 protein |
CTD |
PMID:20722399 |
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NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
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G |
Kif5b |
kinesin family member 5B |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of KIF5B protein |
CTD |
PMID:26984711 |
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NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
EXP |
cyanoginosin LR results in increased expression of KIT |
CTD |
PMID:24025782 |
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NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
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G |
Kpna4 |
karyopherin subunit alpha 4 |
affects expression |
ISO |
cyanoginosin LR affects the expression of KPNA4 protein |
CTD |
PMID:26984711 |
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NCBI chr 2:165,684,345...165,739,874
Ensembl chr 2:165,684,345...165,739,874
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G |
Krt18 |
keratin 18 |
increases expression increases phosphorylation multiple interactions |
ISO |
cyanoginosin LR results in increased expression of KRT18 mRNA cyanoginosin LR results in increased phosphorylation of KRT18 protein SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT18 protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT18 protein] |
CTD |
PMID:17654400 PMID:22960429 |
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NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
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G |
Krt8 |
keratin 8 |
multiple interactions increases expression |
ISO |
cyanoginosin LR results in increased phosphorylation of and affects the expression of KRT8 protein; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein] cyanoginosin LR results in increased expression of KRT8 mRNA |
CTD |
PMID:17654400 PMID:22960429 |
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NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
cyanoginosin LR results in increased expression of LDLR mRNA |
CTD |
PMID:25497113 |
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NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
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G |
Lgals1 |
galectin 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of LGALS1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
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G |
Lgals3 |
galectin 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of LGALS3 mRNA |
CTD |
PMID:17654400 |
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NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
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G |
Lgals3bp |
galectin 3 binding protein |
increases expression |
ISO |
cyanoginosin LR results in increased expression of LGALS3BP mRNA |
CTD |
PMID:17654400 |
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NCBI chr10:107,415,334...107,424,672
Ensembl chr10:107,415,326...107,424,710
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G |
Lpin2 |
lipin 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of LPIN2 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
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G |
Lrp1 |
LDL receptor related protein 1 |
affects expression |
ISO |
cyanoginosin LR affects the expression of LRP1 protein |
CTD |
PMID:26984711 |
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NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
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G |
Lypla2 |
lysophospholipase 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of LYPLA2 protein |
CTD |
PMID:26984711 |
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NCBI chr 5:154,315,033...154,319,629
Ensembl chr 5:154,315,033...154,319,629
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G |
Maged1 |
MAGE family member D1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MAGED1 mRNA |
CTD |
PMID:29518473 |
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NCBI chr X:63,803,194...63,809,715
Ensembl chr X:63,803,189...63,809,861
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G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MAP3K1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
cyanoginosin LR results in increased phosphorylation of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPK1 protein]; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK1 protein; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:20934494 PMID:21983652 PMID:22960429 PMID:23970801 PMID:27393157 PMID:29984889 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk11 |
mitogen-activated protein kinase 11 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MAPK11 mRNA; cyanoginosin LR results in increased expression of MAPK11 protein |
CTD |
PMID:25986756 |
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NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions increases phosphorylation |
EXP |
cyanoginosin LR results in increased phosphorylation of and results in increased activity of MAPK14 protein cyanoginosin LR results in increased phosphorylation of MAPK14 protein |
CTD |
PMID:22000993 |
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NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases expression increases phosphorylation multiple interactions |
ISO |
cyanoginosin LR results in increased expression of MAPK3 mRNA cyanoginosin LR results in increased phosphorylation of MAPK3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPK3 protein]; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK3 protein; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:17654400 PMID:20934494 PMID:21983652 PMID:22960429 PMID:23970801 PMID:27352821 PMID:27393157 PMID:29984889 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
[IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:29984889 |
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NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases expression multiple interactions |
ISO |
cyanoginosin LR results in increased expression of MAPK9 mRNA [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:17654400 PMID:29984889 |
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NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
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G |
Mapt |
microtubule-associated protein tau |
affects phosphorylation increases phosphorylation multiple interactions increases localization |
ISO EXP |
cyanoginosin LR affects the phosphorylation of MAPT protein cyanoginosin LR results in increased phosphorylation of MAPT protein SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]; Ascorbic Acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]; SB 203580 inhibits the reaction [cyanoginosin LR results in increased localization of MAPT protein]; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] |
CTD |
PMID:21934130 PMID:22000993 PMID:23929704 PMID:24142891 PMID:27393157 |
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NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
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G |
Mcat |
malonyl-CoA-acyl carrier protein transacylase |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MCAT protein |
CTD |
PMID:26984711 |
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NCBI chr 7:124,412,762...124,424,966
Ensembl chr 7:124,412,762...124,423,832
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G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
ISO EXP |
cyanoginosin LR results in decreased expression of MDM2 mRNA; cyanoginosin LR results in decreased expression of MDM2 protein |
CTD |
PMID:28414124 PMID:31157505 |
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NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MET mRNA; cyanoginosin LR results in increased expression of MET protein |
CTD |
PMID:28062358 |
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NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
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G |
Mfge8 |
milk fat globule EGF and factor V/VIII domain containing |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MFGE8 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
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G |
Mir100 |
microRNA 100 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR100 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 8:45,746,948...45,747,027
Ensembl chr 8:45,746,948...45,747,027
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G |
Mir137 |
microRNA 137 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MIR137 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
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G |
Mir181a2 |
microRNA 181a-2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR181A-2 mRNA |
CTD |
PMID:25986756 |
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NCBI chr 3:23,150,352...23,150,468
Ensembl chr 3:23,150,352...23,150,468
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G |
Mir19a |
microRNA 19a |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR19A mRNA |
CTD |
PMID:29518473 |
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NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
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G |
Mir204 |
microRNA 204 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR204 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
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G |
Mir27a |
microRNA 27a |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MIR27A mRNA |
CTD |
PMID:29518473 |
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NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
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G |
Mir30b |
microRNA 30b |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MIR30B mRNA |
CTD |
PMID:29518473 |
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NCBI chr 7:109,282,662...109,282,747
Ensembl chr 7:109,282,658...109,282,752
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G |
Mir31 |
microRNA 31 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR31 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 5:107,206,515...107,206,620
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G |
Mir320a |
microRNA 320a |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR320A mRNA |
CTD |
PMID:29518473 |
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NCBI chr15:52,134,276...52,134,357
Ensembl chr15:52,134,276...52,134,357
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G |
Mir33 |
microRNA 33 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MIR33A mRNA |
CTD |
PMID:29518473 |
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NCBI chr 7:123,431,612...123,431,680
Ensembl chr 7:123,431,612...123,431,680
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G |
Mir331 |
microRNA 331 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MIR331 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
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G |
Mir342 |
microRNA 342 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MIR342 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MKI67 protein |
CTD |
PMID:28189720 |
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NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
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G |
Mmgt1 |
membrane magnesium transporter 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MMGT1 protein |
CTD |
PMID:26984711 |
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NCBI chr X:158,966,694...158,978,995
Ensembl chr X:158,966,673...158,978,995
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G |
Mmp13 |
matrix metallopeptidase 13 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MMP13 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
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G |
Mmp2 |
matrix metallopeptidase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MMP2 mRNA; cyanoginosin LR results in increased expression of MMP2 protein |
CTD |
PMID:20934494 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression decreases expression |
ISO |
cyanoginosin LR results in increased expression of MMP9 mRNA; cyanoginosin LR results in increased expression of MMP9 protein cyanoginosin LR results in decreased expression of MMP9 protein |
CTD |
PMID:20934494 PMID:28189720 |
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NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Mrps7 |
mitochondrial ribosomal protein S7 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MRPS7 protein |
CTD |
PMID:26984711 |
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NCBI chr10:104,155,805...104,158,840
Ensembl chr10:104,155,805...104,158,839
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G |
Ms4a7 |
membrane spanning 4-domains A7 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MS4A7 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 1:227,490,777...227,506,819
Ensembl chr 1:227,490,777...227,506,822
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G |
Msn |
moesin |
increases expression |
EXP |
cyanoginosin LR results in increased expression of MSN mRNA |
CTD |
PMID:23342045 |
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NCBI chr X:65,226,834...65,294,192
Ensembl chr X:65,226,748...65,295,810
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G |
Msrb1 |
methionine sulfoxide reductase B1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of MSRB1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of ATP6 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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G |
Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of ATP8 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
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G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression |
EXP |
cyanoginosin LR results in increased expression of COX1 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
increases expression |
EXP |
cyanoginosin LR results in increased expression of COX2 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
increases expression |
EXP |
cyanoginosin LR results in increased expression of COX3 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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G |
Mt-nd1 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of ND1 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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G |
Mt-nd3 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of ND3 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
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G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of ND6 mRNA |
CTD |
PMID:23342045 |
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NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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G |
Mt1 |
metallothionein 1 |
decreases expression increases expression |
ISO |
cyanoginosin LR results in decreased expression of MT1 mRNA cyanoginosin LR results in increased expression of MT1 mRNA |
CTD |
PMID:17383702 PMID:17654400 |
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NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
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G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MT2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
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G |
Mtor |
mechanistic target of rapamycin kinase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of MTOR protein |
CTD |
PMID:25497113 |
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NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
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G |
Mttp |
microsomal triglyceride transfer protein |
affects expression |
ISO |
cyanoginosin LR affects the expression of MTTP protein |
CTD |
PMID:26984711 |
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NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression increases phosphorylation |
ISO |
cyanoginosin LR results in increased expression of MYC mRNA cyanoginosin LR results in increased phosphorylation of MYC protein cyanoginosin LR results in increased expression of MYC mRNA; cyanoginosin LR results in increased expression of MYC protein |
CTD |
PMID:17654400 PMID:20421190 PMID:23891578 PMID:24607848 PMID:26506538 PMID:28062358 |
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NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
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G |
Mylk3 |
myosin light chain kinase 3 |
increases expression decreases methylation |
ISO |
cyanoginosin LR results in increased expression of MYLK3 mRNA cyanoginosin LR results in decreased methylation of MYLK3 gene |
CTD |
PMID:29518473 |
|
NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
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G |
Naip6 |
NLR family, apoptosis inhibitory protein 6 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of NAIP2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:30,377,505...30,418,578
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G |
Nalcn |
sodium leak channel, non-selective |
increases methylation decreases expression |
ISO |
cyanoginosin LR results in increased methylation of NALCN gene cyanoginosin LR results in decreased expression of NALCN mRNA |
CTD |
PMID:29518473 |
|
NCBI chr15:109,734,092...110,046,729
Ensembl chr15:109,735,595...110,046,704
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G |
Necap1 |
NECAP endocytosis associated 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of NECAP1 protein |
CTD |
PMID:26984711 |
|
NCBI chr 4:155,709,712...155,724,801
Ensembl chr 4:155,709,613...155,724,790
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G |
Net1 |
neuroepithelial cell transforming 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of NET1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr17:69,991,786...70,020,977
Ensembl chr17:70,010,794...70,020,982
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G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions affects expression affects response to substance decreases degradation |
ISO |
[cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; cyanoginosin LR inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; cyanoginosin LR promotes the reaction [sulforafan affects the localization of NFE2L2 protein]; cyanoginosin LR results in increased expression of and results in increased activity of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of HMOX1 protein]; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of NQO1 protein] [Thioctic Acid co-treated with cyanoginosin LR] results in increased expression of NFE2L2 protein cyanoginosin LR affects the expression of NFE2L2 protein NFE2L2 protein affects the susceptibility to cyanoginosin LR cyanoginosin LR results in decreased degradation of NFE2L2 protein |
CTD |
PMID:20600217 PMID:20722399 PMID:32061150 |
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NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions increases phosphorylation |
ISO |
cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] cyanoginosin LR results in increased phosphorylation of NFKBIA protein |
CTD |
PMID:23970801 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] |
CTD |
PMID:15712326 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Nox4 |
NADPH oxidase 4 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of NOX4 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
cyanoginosin LR results in increased expression of NQO1 mRNA cyanoginosin LR results in increased expression of NQO1 mRNA; cyanoginosin LR results in increased expression of NQO1 protein [cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; cyanoginosin LR promotes the reaction [sulforafan results in increased expression of NQO1 protein]; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of NQO1 protein] |
CTD |
PMID:17654400 PMID:20600217 PMID:20722399 |
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NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
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G |
Nras |
NRAS proto-oncogene, GTPase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of NRAS mRNA cyanoginosin LR results in increased expression of NRAS mRNA; cyanoginosin LR results in increased expression of NRAS protein |
CTD |
PMID:17654400 PMID:28062358 |
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NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
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G |
Nupr1 |
nuclear protein 1, transcriptional regulator |
increases expression |
ISO |
cyanoginosin LR results in increased expression of NUPR1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
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G |
Ocln |
occludin |
decreases expression |
ISO EXP |
cyanoginosin LR results in decreased expression of OCLN protein |
CTD |
PMID:25986756 PMID:27758031 |
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NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
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G |
Pak1 |
p21 (RAC1) activated kinase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PAK1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO EXP |
cyanoginosin LR results in increased cleavage of PARP1 protein pifithrin inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein] sulforafan inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein] |
CTD |
PMID:21684301 PMID:31157505 |
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NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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G |
Pcyt2 |
phosphate cytidylyltransferase 2, ethanolamine |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PCYT2 protein |
CTD |
PMID:26984711 |
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NCBI chr10:109,788,348...109,795,743
Ensembl chr10:109,788,350...109,795,697
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PDGFRA mRNA |
CTD |
PMID:17654400 |
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NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PDIA4 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
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G |
Pdpk1 |
3-phosphoinositide dependent protein kinase-1 |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of PDPK1 protein |
CTD |
PMID:20421190 |
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NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
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G |
Pdzk1 |
PDZ domain containing 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PDZK1 protein |
CTD |
PMID:26984711 |
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NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
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G |
Pepd |
peptidase D |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PEPD protein |
CTD |
PMID:26984711 |
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NCBI chr 1:90,820,670...91,285,128
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G |
Pfn1 |
profilin 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PFN1 mRNA |
CTD |
PMID:17383702 |
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NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
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G |
Pfn2 |
profilin 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PFN2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:147,953,858...147,959,692
Ensembl chr 2:147,955,196...148,050,438
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G |
Pgd |
phosphogluconate dehydrogenase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PGD mRNA |
CTD |
PMID:17654400 |
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NCBI chr 5:165,966,128...165,982,327
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G |
Pigr |
polymeric immunoglobulin receptor |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PIGR mRNA |
CTD |
PMID:17383702 |
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NCBI chr13:47,564,176...47,592,093
Ensembl chr13:47,572,219...47,591,699
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G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PIK3R3 mRNA; cyanoginosin LR results in decreased expression of PIK3R3 protein |
CTD |
PMID:28414124 |
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NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
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G |
Pitrm1 |
pitrilysin metallopeptidase 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PITRM1 protein |
CTD |
PMID:26984711 |
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NCBI chr17:68,477,423...68,509,113
Ensembl chr17:68,477,446...68,509,120
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G |
Plin3 |
perilipin 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PLIN3 protein |
CTD |
PMID:26984711 |
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NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
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G |
Plk1 |
polo-like kinase 1 |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of PLK1 protein |
CTD |
PMID:26506538 |
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NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
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G |
Plk3 |
polo-like kinase 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PLK3 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
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G |
Pmpcb |
peptidase, mitochondrial processing subunit beta |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PMPCB protein |
CTD |
PMID:26984711 |
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NCBI chr 4:9,908,838...9,921,615
Ensembl chr 4:9,908,831...9,921,610
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G |
Ppp2ca |
protein phosphatase 2 catalytic subunit alpha |
affects binding multiple interactions |
EXP ISO |
cyanoginosin LR binds to PPP2CA protein [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of PPP2CA protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of PPP2CA protein; cyanoginosin LR inhibits the reaction [IGBP1 protein binds to PPP2CA protein]; cyanoginosin LR inhibits the reaction [PPP2CA protein binds to IGBP1 protein]; cyanoginosin LR inhibits the reaction [PPP2CA protein binds to PPP2R1A protein]; cyanoginosin LR inhibits the reaction [PPP2R1A protein binds to PPP2CA protein]; cyanoginosin LR results in increased expression of and results in increased phosphorylation of and results in increased methylation of PPP2CA protein cyanoginosin LR results in increased phosphorylation of and results in decreased activity of PPP2CA protein |
CTD |
PMID:22000993 PMID:27393157 PMID:29984889 |
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NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
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G |
Ppp2r1a |
protein phosphatase 2 scaffold subunit A alpha |
increases expression decreases expression multiple interactions |
EXP ISO |
cyanoginosin LR results in increased expression of PPP2R1A protein cyanoginosin LR results in decreased expression of PPP2R1A protein cyanoginosin LR inhibits the reaction [PPP2CA protein binds to PPP2R1A protein]; cyanoginosin LR inhibits the reaction [PPP2R1A protein binds to PPP2CA protein] |
CTD |
PMID:18214937 PMID:22000993 PMID:27393157 PMID:29984889 |
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NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
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G |
Ppp2r2a |
protein phosphatase 2, regulatory subunit B, alpha |
affects expression decreases expression multiple interactions |
EXP ISO |
cyanoginosin LR affects the expression of PPP2R2A protein cyanoginosin LR results in decreased expression of PPP2R2A protein cyanoginosin LR results in increased expression of and affects the localization of PPP2R2A protein |
CTD |
PMID:22000993 PMID:23436320 PMID:27393157 |
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NCBI chr15:43,673,958...43,733,182
Ensembl chr15:43,673,960...43,733,182
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G |
Prkar2b |
protein kinase cAMP-dependent type II regulatory subunit beta |
increases methylation decreases expression |
ISO |
cyanoginosin LR results in increased methylation of PRKAR2B gene cyanoginosin LR results in decreased expression of PRKAR2B mRNA |
CTD |
PMID:29518473 |
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NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
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G |
Prkd3 |
protein kinase D3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of PRKD3 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 6:1,546,018...1,622,232
Ensembl chr 6:1,548,415...1,622,196
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G |
Prune1 |
prune exopolyphosphatase 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PRUNE1 protein |
CTD |
PMID:26984711 |
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NCBI chr 2:196,427,714...196,457,105
Ensembl chr 2:196,427,710...196,456,481
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G |
Pten |
phosphatase and tensin homolog |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of PTEN mRNA; cyanoginosin LR results in decreased expression of PTEN protein |
CTD |
PMID:28062358 |
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NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
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G |
Rad21 |
RAD21 cohesin complex component |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of RAD21 protein |
CTD |
PMID:26984711 |
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NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673
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G |
Ralb |
RAS like proto-oncogene B |
increases expression |
ISO |
cyanoginosin LR results in increased expression of RALB mRNA |
CTD |
PMID:17654400 |
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NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
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G |
Rbm39 |
RNA binding motif protein 39 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of RBM39 protein |
CTD |
PMID:26984711 |
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NCBI chr 3:151,691,498...151,724,723
Ensembl chr 3:151,691,514...151,724,654
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G |
Rdx |
radixin |
decreases expression |
EXP |
cyanoginosin LR results in decreased expression of RDX mRNA |
CTD |
PMID:23342045 |
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NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases activity |
ISO |
cyanoginosin LR results in increased activity of RELA protein |
CTD |
PMID:30076769 |
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NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Rhob |
ras homolog family member B |
increases expression |
ISO |
cyanoginosin LR results in increased expression of RHOB mRNA |
CTD |
PMID:17654400 |
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NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
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G |
Rhoc |
ras homolog family member C |
increases expression |
ISO |
cyanoginosin LR results in increased expression of RHOC mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
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G |
Rhoq |
ras homolog family member Q |
increases expression |
ISO |
cyanoginosin LR results in increased expression of RHOQ mRNA |
CTD |
PMID:17654400 |
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NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
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G |
Rit1 |
Ras-like without CAAX 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of RIT1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
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G |
Rps6 |
ribosomal protein S6 |
increases phosphorylation |
ISO |
cyanoginosin LR results in increased phosphorylation of RPS6 protein |
CTD |
PMID:26506538 |
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NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
increases phosphorylation increases expression multiple interactions |
EXP ISO |
cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein cyanoginosin LR results in increased expression of RPS6KB1 protein modified form 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein]; cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]; INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]]; Sirolimus inhibits the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]; Sirolimus inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]] naringin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:15342961 PMID:26506538 PMID:28984034 PMID:31714646 |
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NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
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G |
RT1-A2 |
RT1 class Ia, locus A2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of H2-D1 protein |
CTD |
PMID:26984711 |
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NCBI chr20:5,374,990...5,378,536
Ensembl chr20:5,374,985...5,378,539
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G |
S100a11 |
S100 calcium binding protein A11 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of S100A11 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
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G |
Serpinb6a |
serpin family B member 6A |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SERPINB6A mRNA |
CTD |
PMID:17654400 |
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NCBI chr17:32,154,747...32,209,598
Ensembl chr17:32,190,801...32,209,590
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G |
Siah1 |
siah E3 ubiquitin protein ligase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SIAH1 mRNA |
CTD |
PMID:20421190 |
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NCBI chr19:21,372,163...21,395,773
Ensembl chr19:21,372,163...21,395,767
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G |
Slc10a1 |
solute carrier family 10 member 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of SLC10A1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
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G |
Slc22a7 |
solute carrier family 22 member 7 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of SLC22A7 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
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G |
Slc2a2 |
solute carrier family 2 member 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SLC2A2 mRNA |
CTD |
PMID:25497113 |
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NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SLC7A11 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
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G |
Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of SLCO1A4 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
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G |
Slco1a5 |
solute carrier organic anion transporter family, member 1A5 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of SLCO1A5 mRNA |
CTD |
PMID:22579952 |
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NCBI chr 4:176,445,856...176,528,117
Ensembl chr 4:176,445,858...176,528,110
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G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
decreases expression increases import multiple interactions increases uptake increases response to substance affects response to substance |
ISO |
cyanoginosin LR results in decreased expression of SLCO1B2 mRNA SLCO1B3 protein results in increased import of cyanoginosin LR Cyclosporine inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Dehydroepiandrosterone Sulfate inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR]; Okadaic Acid inhibits the reaction [SLCO1B3 protein results in increased uptake of cyanoginosin LR]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR]; Taurocholic Acid inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR] SLCO1B2 protein affects the susceptibility to cyanoginosin LR SLCO1B2 results in increased susceptibility to cyanoginosin LR |
CTD |
PMID:17369605 PMID:17654400 PMID:18296417 PMID:19027771 PMID:20171238 PMID:25456266 PMID:26134461 |
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NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
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G |
Slco3a1 |
solute carrier organic anion transporter family, member 3a1 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of SLCO3A1 mRNA; cyanoginosin LR results in increased expression of SLCO3A1 protein |
CTD |
PMID:22579952 |
|
NCBI chr 1:135,790,854...136,073,640
Ensembl chr 1:135,790,810...136,073,540
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G |
Slco6b1 |
solute carrier organic anion transporter family member 6B1 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of SLCO6B1 mRNA |
CTD |
PMID:22579952 |
|
NCBI chr 9:104,388,232...104,468,005
Ensembl chr 9:104,392,850...104,467,973
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G |
Smad2 |
SMAD family member 2 |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of SMAD2 protein]; cyanoginosin LR results in increased expression of and results in increased phosphorylation of SMAD2 protein; SMAD2 protein affects the reaction [cyanoginosin LR results in decreased expression of CDH1 protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of SNAI1 protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of VIM protein] |
CTD |
PMID:27856280 |
|
NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
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G |
Smoc2 |
SPARC related modular calcium binding 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SMOC2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:56,242,289...56,374,106
Ensembl chr 1:56,242,346...56,374,120
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G |
Snai1 |
snail family transcriptional repressor 1 |
increases expression multiple interactions |
ISO |
cyanoginosin LR results in increased expression of SNAI1 mRNA; cyanoginosin LR results in increased expression of SNAI1 protein SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of SNAI1 protein] |
CTD |
PMID:27856280 |
|
NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
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G |
Sod1 |
superoxide dismutase 1 |
increases activity |
ISO |
cyanoginosin LR results in increased activity of SOD1 protein |
CTD |
PMID:30076769 |
|
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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G |
Sod2 |
superoxide dismutase 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of SOD2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
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G |
Spint2 |
serine peptidase inhibitor, Kunitz type, 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SPINT2 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr 1:87,199,373...87,221,826
Ensembl chr 1:87,199,313...87,221,892
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of SREBF1 mRNA |
CTD |
PMID:17654400 |
|
NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
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G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SREBF2 mRNA |
CTD |
PMID:25497113 |
|
NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
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G |
Stmn1 |
stathmin 1 |
decreases expression |
EXP |
cyanoginosin LR results in decreased expression of STMN1 mRNA |
CTD |
PMID:23342045 |
|
NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
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G |
Suclg2 |
succinate-CoA ligase GDP-forming subunit beta |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of SUCLG2 mRNA |
CTD |
PMID:17383702 |
|
NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
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|
G |
Sult1b1 |
sulfotransferase family 1B member 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SULT1B1 protein |
CTD |
PMID:26984711 |
|
NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
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|
G |
Syne1 |
spectrin repeat containing nuclear envelope protein 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of SYNE1 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 1:41,608,287...41,763,591 NCBI chr 1:41,844,840...42,086,662
Ensembl chr 1:41,608,418...42,077,535
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G |
Tgfb2 |
transforming growth factor, beta 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TGFB2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
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G |
Tgm2 |
transglutaminase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TGM2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
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G |
Thra |
thyroid hormone receptor alpha |
increases expression |
ISO |
cyanoginosin LR results in increased expression of THRA protein |
CTD |
PMID:25497113 |
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NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
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G |
Thrsp |
thyroid hormone responsive |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of THRSP mRNA |
CTD |
PMID:17654400 |
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NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
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G |
Tjp1 |
tight junction protein 1 |
decreases expression |
ISO EXP |
cyanoginosin LR results in decreased expression of TJP1 protein |
CTD |
PMID:25986756 PMID:27758031 |
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NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
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G |
Tmsb10 |
thymosin, beta 10 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TMSB10 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 4:100,882,216...100,883,303
Ensembl chr 4:100,882,216...100,883,275
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G |
Tmsb4x |
thymosin beta 4, X-linked |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TMSB4X mRNA |
CTD |
PMID:17654400 |
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NCBI chr X:28,593,405...28,617,267
Ensembl chr X:28,593,405...28,595,395
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression decreases expression |
ISO |
cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] cyanoginosin LR results in increased expression of TNF mRNA; cyanoginosin LR results in increased expression of TNF protein cyanoginosin LR results in decreased expression of TNF mRNA cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cyanoginosin LR promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL6 protein]; sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of TNF mRNA] |
CTD |
PMID:15712326 PMID:21684301 PMID:23454832 PMID:23970801 PMID:26984711 PMID:28189720 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Tnfrsf12a |
TNF receptor superfamily member 12A |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TNFRSF12A mRNA |
CTD |
PMID:17654400 |
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NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
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G |
Tnp2 |
transition protein 2 |
decreases expression |
EXP |
cyanoginosin LR results in decreased expression of TNP2 mRNA |
CTD |
PMID:24025782 |
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NCBI chr10:4,953,898...4,954,626
Ensembl chr10:4,953,879...4,954,624
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G |
Tnpo1 |
transportin 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of TNPO1 protein |
CTD |
PMID:26984711 |
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NCBI chr 2:29,056,219...29,126,882
Ensembl chr 2:29,056,219...29,121,104
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G |
Tp53 |
tumor protein p53 |
increases expression multiple interactions increases phosphorylation |
ISO EXP |
cyanoginosin LR results in increased expression of TP53; cyanoginosin LR results in increased expression of TP53 mRNA; cyanoginosin LR results in increased expression of TP53 protein [cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased expression of TP53 protein; pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of TP53 protein] cyanoginosin LR results in increased expression of TRP53 protein cyanoginosin LR results in increased phosphorylation of TRP53 protein cyanoginosin LR results in increased phosphorylation of TP53 protein |
CTD |
PMID:16624733 PMID:18214937 PMID:20421190 PMID:22539157 PMID:23454832 PMID:23891578 PMID:25410294 PMID:28414124 PMID:31157505 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Tpm1 |
tropomyosin 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TPM1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
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G |
Treh |
trehalase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TREH mRNA |
CTD |
PMID:17654400 |
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NCBI chr 8:48,983,802...48,998,072
Ensembl chr 8:48,983,802...48,997,191
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G |
Trib3 |
tribbles pseudokinase 3 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TRIB3 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
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G |
Trrap |
transformation/transcription domain-associated protein |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TRRAP mRNA |
CTD |
PMID:29518473 |
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NCBI chr12:11,537,950...11,627,563
Ensembl chr12:11,537,950...11,627,563
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G |
Ttn |
titin |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TTN mRNA |
CTD |
PMID:29518473 |
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NCBI chr 3:63,565,160...63,837,815
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G |
Ttr |
transthyretin |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of TTR mRNA |
CTD |
PMID:17654400 |
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NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
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G |
Tub |
TUB bipartite transcription factor |
affects expression decreases acetylation |
EXP |
cyanoginosin LR affects the expression of TUB protein modified form cyanoginosin LR results in decreased acetylation of TUB protein |
CTD |
PMID:22000993 |
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NCBI chr 1:173,550,929...173,629,550
Ensembl chr 1:173,607,101...173,625,550
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G |
Txndc12 |
thioredoxin domain containing 12 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of TXNDC12 protein |
CTD |
PMID:26984711 |
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NCBI chr 5:128,450,830...128,475,858
Ensembl chr 5:128,450,680...128,475,864
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of TXNRD1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
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G |
Uba2 |
ubiquitin-like modifier activating enzyme 2 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of UBA2 protein |
CTD |
PMID:26984711 |
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NCBI chr 1:90,010,681...90,035,522
Ensembl chr 1:90,011,306...90,035,522
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G |
Ugdh |
UDP-glucose 6-dehydrogenase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of UGDH mRNA |
CTD |
PMID:17654400 |
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NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
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G |
Ugp2 |
UDP-glucose pyrophosphorylase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of UGP2 mRNA |
CTD |
PMID:17654400 |
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NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
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G |
Upp2 |
uridine phosphorylase 2 |
increases expression |
ISO |
cyanoginosin LR results in increased expression of UPP2 mRNA |
CTD |
PMID:17383702 |
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NCBI chr 3:44,806,106...44,846,464
Ensembl chr 3:44,806,106...44,846,464
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G |
Usp7 |
ubiquitin specific peptidase 7 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of USP7 protein |
CTD |
PMID:26984711 |
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NCBI chr10:6,930,462...7,019,910
Ensembl chr10:6,975,244...7,018,930
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G |
Vasp |
vasodilator-stimulated phosphoprotein |
increases phosphorylation multiple interactions |
ISO |
cyanoginosin LR results in increased phosphorylation of VASP protein [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of VASP protein modified form; cyanoginosin LR results in increased phosphorylation of and affects the localization of VASP protein; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VASP protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VASP protein] |
CTD |
PMID:23929704 PMID:24677693 PMID:27352821 PMID:27393157 PMID:29984889 |
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NCBI chr 1:80,170,608...80,185,882
Ensembl chr 1:80,170,619...80,185,882
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G |
Vdac1 |
voltage-dependent anion channel 1 |
increases expression |
EXP |
cyanoginosin LR results in increased expression of VDAC1 mRNA; cyanoginosin LR results in increased expression of VDAC1 protein |
CTD |
PMID:31157505 |
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NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
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G |
Vim |
vimentin |
increases phosphorylation increases expression affects localization multiple interactions |
ISO EXP |
cyanoginosin LR results in increased phosphorylation of VIM protein cyanoginosin LR results in increased expression of VIM mRNA cyanoginosin LR affects the localization of VIM protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in decreased expression of VIM protein]; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VIM protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of VIM protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VIM protein] |
CTD |
PMID:22960429 PMID:23342045 PMID:27393157 PMID:27856280 |
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NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
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G |
Wee1 |
WEE1 G2 checkpoint kinase |
increases expression |
ISO |
cyanoginosin LR results in increased expression of WEE1 mRNA |
CTD |
PMID:17654400 |
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NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
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G |
Xylt1 |
xylosyltransferase 1 |
decreases expression |
ISO |
cyanoginosin LR results in decreased expression of XYLT1 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
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G |
Ywhag |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma |
increases expression |
ISO |
cyanoginosin LR results in increased expression of YWHAG mRNA |
CTD |
PMID:17654400 |
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NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
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G |
Ywhah |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
increases expression |
ISO |
cyanoginosin LR results in increased expression of YWHAH mRNA |
CTD |
PMID:17654400 |
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NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
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G |
Ywhaz |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
increases expression |
ISO |
cyanoginosin LR results in increased expression of YWHAZ mRNA |
CTD |
PMID:17654400 |
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NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
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G |
Zfp704 |
zinc finger protein 704 |
decreases methylation increases expression |
ISO |
cyanoginosin LR results in decreased methylation of ZNF704 gene cyanoginosin LR results in increased expression of ZNF704 mRNA |
CTD |
PMID:29518473 |
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NCBI chr 2:94,377,059...94,559,838
Ensembl chr 2:94,377,072...94,551,529
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G |
Clu |
clusterin |
multiple interactions |
EXP |
omega-Conotoxin GVIA inhibits the reaction [methoxyacetic acid results in increased expression of and results in increased secretion of CLU protein] |
CTD |
PMID:14656996 |
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NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
[Nifedipine co-treated with omega-Conotoxin GVIA co-treated with omega-Agatoxin IVA] inhibits the reaction [Potassium Chloride affects the expression of FOS mRNA] |
CTD |
PMID:20211981 |
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NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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G |
Kcna1 |
potassium voltage-gated channel subfamily A member 1 |
multiple interactions |
EXP |
[Nifedipine co-treated with omega-Conotoxin GVIA co-treated with omega-Agatoxin IVA] promotes the reaction [Potassium Chloride results in increased expression of KCNA1 mRNA] |
CTD |
PMID:20211981 |
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NCBI chr 4:159,190,781...159,192,526
Ensembl chr 4:159,190,804...159,192,526
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G |
Kcnc3 |
potassium voltage-gated channel subfamily C member 3 |
multiple interactions |
EXP |
[Nifedipine co-treated with omega-Conotoxin GVIA co-treated with omega-Agatoxin IVA] inhibits the reaction [Potassium Chloride results in increased expression of KCNC3 mRNA] |
CTD |
PMID:20211981 |
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NCBI chr 1:100,593,453...100,607,874
Ensembl chr 1:100,593,680...100,607,874
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G |
Sct |
secretin |
multiple interactions |
EXP |
omega-Conotoxin GVIA inhibits the reaction [Potassium Chloride results in increased secretion of SCT protein] |
CTD |
PMID:16888165 |
|
NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668
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G |
Snca |
synuclein alpha |
multiple interactions |
EXP |
omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] |
CTD |
PMID:17179863 |
|
NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
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G |
Tac1 |
tachykinin, precursor 1 |
multiple interactions |
EXP |
omega-Conotoxin GVIA inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form] |
CTD |
PMID:2325850 |
|
NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression |
EXP |
Oxytocin results in increased expression of BCL2 protein |
CTD |
PMID:23707249 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Egfr |
epidermal growth factor receptor |
increases expression |
EXP |
Oxytocin results in increased expression of EGFR protein modified form |
CTD |
PMID:23707249 |
|
NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP |
Oxytocin results in increased expression of FOS protein Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein] |
CTD |
PMID:20731630 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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G |
Gdf9 |
growth differentiation factor 9 |
increases expression |
EXP |
Oxytocin results in increased expression of GDF9 protein |
CTD |
PMID:23707249 |
|
NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
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G |
Has2 |
hyaluronan synthase 2 |
increases expression |
EXP |
Oxytocin results in increased expression of HAS2 protein |
CTD |
PMID:23707249 |
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NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
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G |
Klf4 |
Kruppel like factor 4 |
multiple interactions increases expression |
ISO |
KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]]; KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 protein]]; MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein]; MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of KLF4 protein] Oxytocin results in increased expression of KLF4 mRNA; Oxytocin results in increased expression of KLF4 protein |
CTD |
PMID:29104011 |
|
NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
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G |
Map2k5 |
mitogen activated protein kinase kinase 5 |
multiple interactions |
ISO |
MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MAP2K5 protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein] |
CTD |
PMID:29104011 |
|
NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases expression |
EXP |
Oxytocin results in increased expression of MAPK1 protein modified form |
CTD |
PMID:23707249 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases expression |
EXP |
Oxytocin results in increased expression of MAPK3 protein modified form |
CTD |
PMID:23707249 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions |
ISO |
MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 mRNA]; MEF2A protein promotes the reaction [Oxytocin results in increased expression of KLF4 protein] |
CTD |
PMID:29104011 |
|
NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
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G |
Mknk2 |
MAPK interacting serine/threonine kinase 2 |
multiple interactions |
EXP |
Oxytocin inhibits the reaction [Cisplatin results in increased expression of MKNK2 mRNA] |
CTD |
PMID:21993003 |
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NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases response to substance |
EXP |
MMP2 protein results in decreased susceptibility to Oxytocin |
CTD |
PMID:22496348 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases response to substance |
EXP |
MMP9 protein results in decreased susceptibility to Oxytocin |
CTD |
PMID:22496348 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Noxo1 |
NADPH oxidase organizer 1 |
multiple interactions |
EXP |
Oxytocin inhibits the reaction [Cisplatin results in increased expression of NOXO1 mRNA] |
CTD |
PMID:21993003 |
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NCBI chr10:14,062,331...14,066,918
Ensembl chr10:14,062,331...14,066,918
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G |
Oxtr |
oxytocin receptor |
multiple interactions |
EXP |
Oxytocin analog binds to and results in decreased activity of OXTR protein |
CTD |
PMID:9502799 |
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NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
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G |
Plcb1 |
phospholipase C beta 1 |
affects localization |
ISO |
Oxytocin affects the localization of PLCB1 protein |
CTD |
PMID:11579162 |
|
NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
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G |
Plcb3 |
phospholipase C beta 3 |
affects localization |
ISO |
Oxytocin affects the localization of PLCB3 protein |
CTD |
PMID:11579162 |
|
NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
EXP |
Oxytocin results in increased expression of PTGS2 protein |
CTD |
PMID:23707249 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Sele |
selectin E |
multiple interactions |
ISO |
KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE mRNA]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein] |
CTD |
PMID:29104011 |
|
NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
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G |
Tnfaip6 |
TNF alpha induced protein 6 |
increases expression |
EXP |
Oxytocin results in increased expression of TNFAIP6 protein |
CTD |
PMID:23707249 |
|
NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 protein]]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 mRNA]; Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of VCAM1 protein] |
CTD |
PMID:29104011 |
|
NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL11 protein] |
CTD |
PMID:26882889 |
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NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL2 protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]] |
CTD |
PMID:26882889 PMID:28555929 |
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NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions decreases secretion |
ISO |
Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CCL3 protein]]; Acetylcysteine promotes the reaction [Polymyxin B results in decreased secretion of CCL3 protein]; Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL3 protein]; Polymyxin B inhibits the reaction [Dust results in increased expression of CCL3 mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CCL3 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine results in decreased secretion of CCL3 protein] |
CTD |
PMID:26882889 PMID:28555929 |
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NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL5 protein] Polymyxin B inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL5 protein] |
CTD |
PMID:26882889 PMID:29348435 |
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NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein] |
CTD |
PMID:26882889 |
|
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
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G |
Cd80 |
Cd80 molecule |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Adenylate Cyclase Toxin results in increased expression of CD80 protein] |
CTD |
PMID:14977963 |
|
NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
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G |
Cd86 |
CD86 molecule |
increases expression multiple interactions |
ISO |
Polymyxin B results in increased expression of CD86 protein Polymyxin B inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CD86 protein] Polymyxin B inhibits the reaction [Adenylate Cyclase Toxin results in increased expression of CD86 protein] |
CTD |
PMID:14977963 PMID:15671028 PMID:30944281 |
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NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions decreases expression |
ISO |
Polymyxin B inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein] Polymyxin B results in decreased expression of CSF2 protein |
CTD |
PMID:31442584 |
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NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]; Polymyxin B promotes the reaction [Cadmium Chloride results in increased expression of CSF3 protein] |
CTD |
PMID:26790433 |
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NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[Polymyxin B co-treated with Particulate Matter] results in increased expression of CXCL1 protein; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CXCL1 protein]; Polymyxin B inhibits the reaction [Dust results in increased expression of CXCL1 mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]] |
CTD |
PMID:26882889 PMID:28555929 |
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NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Polymyxin B promotes the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:20801209 |
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NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
EXP |
Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein] |
CTD |
PMID:18079364 |
|
NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein] |
CTD |
PMID:18079364 |
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NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
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G |
Ddx58 |
DEXD/H-box helicase 58 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of DDX58 mRNA] |
CTD |
PMID:27183587 |
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NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Alpha-Amanitin results in decreased expression of GAPDH mRNA] |
CTD |
PMID:26385100 |
|
NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein]; Polymyxin B inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein] |
CTD |
PMID:30891624 |
|
NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CXCL8 protein]; Polymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA] |
CTD |
PMID:22014880 |
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NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]] |
CTD |
PMID:28555929 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ICAM1 protein]; Polymyxin B inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] |
CTD |
PMID:24080332 PMID:30944281 |
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NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Adenylate Cyclase Toxin results in increased expression of IL10 protein] |
CTD |
PMID:14977963 |
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NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]] |
CTD |
PMID:26882889 |
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NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:9278343 PMID:26882889 |
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NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
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G |
Il13 |
interleukin 13 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL13 protein] |
CTD |
PMID:26882889 |
|
NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] |
CTD |
PMID:21703343 |
|
NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Polymyxin B inhibits the reaction [Vehicle Emissions results in increased secretion of IL1B protein] Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL1B protein]; Polymyxin B inhibits the reaction [Dust results in increased expression of IL1B mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA] |
CTD |
PMID:14993811 PMID:18406506 PMID:26882889 PMID:27393915 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il5 |
interleukin 5 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein] |
CTD |
PMID:26882889 |
|
NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein] Polymyxin B results in decreased expression of IL6 protein Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of IL6] Dextran Sulfate inhibits the reaction [Polymyxin B results in decreased expression of IL6 protein]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL6 protein]; Polymyxin B inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Polymyxin B inhibits the reaction [Dust results in increased expression of IL6 mRNA]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]] |
CTD |
PMID:8886760 PMID:12185005 PMID:20549640 PMID:21784459 PMID:26882889 PMID:28555929 PMID:31442584 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Polymyxin B results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Polymyxin B results in increased phosphorylation of and results in increased activity of MAPK1 protein Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]]; Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:15671028 PMID:28555929 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Polymyxin B results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Polymyxin B results in increased phosphorylation of and results in increased activity of MAPK3 protein Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]]; Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:15671028 PMID:28555929 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]; Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]; Polymyxin B inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]] |
CTD |
PMID:18986645 |
|
NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
[Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein]; Polymyxin B inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein] |
CTD |
PMID:30891624 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G |
Mrgprx2 |
MAS related GPR family member X2 |
increases response to substance multiple interactions |
ISO |
MRGPRX2 protein results in increased susceptibility to Polymyxin B MRGPRX2 protein affects the reaction [Polymyxin B results in increased secretion of OGA protein] |
CTD |
PMID:31132327 |
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NCBI chr 1:103,743,746...103,760,945
Ensembl chr 1:103,741,503...103,760,913
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
[Particulate Matter co-treated with Acetylcysteine co-treated with Polymyxin B] results in increased secretion of MYD88 protein; [Particulate Matter co-treated with Polymyxin B] results in increased secretion of MYD88 protein; MYD88 protein affects the reaction [[Particulate Matter co-treated with Acetylcysteine co-treated with Polymyxin B] results in increased secretion of MYD88 protein]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]] |
CTD |
PMID:28555929 |
|
NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP ISO |
Polymyxin B inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:12568917 PMID:23500011 |
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NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Oga |
O-GlcNAcase |
increases secretion multiple interactions |
ISO |
Polymyxin B results in increased secretion of OGA protein MRGPRX2 protein affects the reaction [Polymyxin B results in increased secretion of OGA protein] |
CTD |
PMID:31132327 |
|
NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Polymyxin B affects the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]] |
CTD |
PMID:23500011 PMID:27393915 PMID:28555929 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
Polymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA] |
CTD |
PMID:22014880 |
|
NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression increases secretion |
ISO EXP |
Dextran Sulfate inhibits the reaction [Polymyxin B results in decreased expression of TNF protein]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]]; Polymyxin B inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Polymyxin B inhibits the reaction [Dust results in increased expression of TNF mRNA]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]] Polymyxin B results in increased secretion of TNF protein Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of TNF] Polymyxin B inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; Polymyxin B inhibits the reaction [Vehicle Emissions results in increased secretion of TNF protein] |
CTD |
PMID:8886760 PMID:12185005 PMID:18406506 PMID:26882889 PMID:28555929 PMID:29348435 PMID:31132327 PMID:31442584 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Kcna5 |
potassium voltage-gated channel subfamily A member 5 |
multiple interactions |
EXP |
Somatostatin inhibits the reaction [Dexamethasone results in increased expression of KCNA5 mRNA] |
CTD |
PMID:15955845 |
|
NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
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G |
Sstr1 |
somatostatin receptor 1 |
increases expression |
ISO |
Somatostatin results in increased expression of SSTR1 mRNA |
CTD |
PMID:18575731 |
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NCBI chr 6:79,252,914...79,258,611
Ensembl chr 6:79,254,339...79,258,611
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G |
Sstr2 |
somatostatin receptor 2 |
increases expression |
ISO |
Somatostatin results in increased expression of SSTR2 mRNA |
CTD |
PMID:18575731 |
|
NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
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G |
Sstr3 |
somatostatin receptor 3 |
increases expression |
ISO |
Somatostatin results in increased expression of SSTR3 mRNA |
CTD |
PMID:18575731 |
|
NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
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G |
Sstr4 |
somatostatin receptor 4 |
increases expression |
ISO |
Somatostatin results in increased expression of SSTR4 mRNA |
CTD |
PMID:18575731 |
|
NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644
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G |
Sstr5 |
somatostatin receptor 5 |
increases expression |
ISO |
Somatostatin results in increased expression of SSTR5 mRNA |
CTD |
PMID:18575731 |
|
NCBI chr10:14,847,749...14,853,827
Ensembl chr10:14,847,749...14,853,827
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Thiostrepton results in increased expression of BAX protein |
CTD |
PMID:22321511 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
Thiostrepton results in decreased expression of BCL2 protein |
CTD |
PMID:22321511 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
Thiostrepton results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:22321511 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
decreases expression |
ISO |
Thiostrepton results in decreased expression of CCL3 mRNA |
CTD |
PMID:22321511 |
|
NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
decreases expression |
ISO |
Thiostrepton results in decreased expression of CCL4 mRNA |
CTD |
PMID:22321511 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Thiostrepton results in decreased expression of CCND1 mRNA |
CTD |
PMID:22321511 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Thiostrepton results in increased expression of CDKN1A mRNA |
CTD |
PMID:22321511 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cryab |
crystallin, alpha B |
increases expression |
ISO |
Thiostrepton results in increased expression of CRYAB mRNA |
CTD |
PMID:22321511 |
|
NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Thiostrepton results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:22321511 |
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NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression |
ISO |
Thiostrepton results in decreased expression of CYP2E1 mRNA |
CTD |
PMID:22321511 |
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NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Thiostrepton results in increased expression of DDIT3 mRNA |
CTD |
PMID:22321511 |
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NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
increases expression |
ISO |
Thiostrepton results in increased expression of DNAJA1 mRNA |
CTD |
PMID:22321511 |
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NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
ISO |
Thiostrepton results in increased expression of DNAJB4 mRNA |
CTD |
PMID:22321511 |
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NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases expression |
ISO |
Thiostrepton results in increased expression of EIF2S1 protein modified form |
CTD |
PMID:22321511 |
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NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Thiostrepton results in increased expression of GADD45A mRNA |
CTD |
PMID:22321511 |
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NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Thiostrepton results in increased expression of GDF15 mRNA |
CTD |
PMID:22321511 |
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NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
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