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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:2453 term browser browse the term
Definition:An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.
Synonyms:exact_synonym: 2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one
 related_synonym: Formula=C8H11N5O3;   InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15);   InChIKey=MKUXAQIIEYXACX-UHFFFAOYSA-N;   SMILES=Nc1nc2n(COCCO)cnc2c(=O)[nH]1;   Zovir;   aciclovir;   aciclovirum;   acycloguanosine
 alt_id: CHEBI:40459
 xref: Beilstein:1219402;   CAS:59277-89-3;   DrugBank:DB00787;   Drug_Central:85;   HMDB:HMDB0014925;   KEGG:C06810;   KEGG:D00222;   LINCS:LSM-5459
 xref_mesh: MESH:D000212
 xref: PDBeChem:AC2;   PMID:11687127;   PMID:11994034;   PMID:24346595;   PMID:26024233;   PMID:28166217;   PMID:8308511;   Patent:DE2539963;   Patent:US4199574;   Reaxys:1219402;   Wikipedia:Acyclovir

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acyclovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVP arginine vasopressin decreases activity EXP Acyclovir results in decreased activity of AVP protein CTD PMID:2724137 NCBI chr24:18,183,057...18,184,827
Ensembl chr24:18,183,057...18,184,883
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  CHEBI ontology 397
    role 397
      biological role 397
        biochemical role 356
          antimetabolite 3
            acyclovir 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 397
    subatomic particle 397
      composite particle 397
        hadron 397
          baryon 397
            nucleon 397
              atomic nucleus 397
                atom 397
                  main group element atom 390
                    p-block element atom 390
                      carbon group element atom 379
                        carbon atom 378
                          organic molecular entity 378
                            organic molecule 368
                              organic cyclic compound 351
                                organic heterocyclic compound 314
                                  organic heteropolycyclic compound 86
                                    organic heterobicyclic compound 43
                                      imidazopyrimidine 21
                                        purines 21
                                          aminopurine 2
                                            2-aminopurines 2
                                              guanine 2
                                                acyclovir 1
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