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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:halogen molecular entity
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Accession:CHEBI:24471 term browser browse the term
Synonyms:related_synonym: halogen compounds;   halogen molecular entities


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1-chloro-2,4-dinitrobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100739508 glutathione S-transferase P-like affects metabolic processing EXP GSTP1 protein affects the metabolism of Dinitrochlorobenzene CTD PMID:14573868 NCBI chr 2:5,005,498...5,009,247 JBrowse link
2,2',4,4',5,5'-hexachlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 decreases activity EXP 2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CYP11A1 protein CTD PMID:16151981 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP19A3 cytochrome P450 19A3 multiple interactions
decreases activity		 EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein
2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CYP19A1 protein		 CTD PMID:16151981 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 multiple interactions
decreases activity		 EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Androstenedione] results in increased activity of HSD17B1 protein
2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of HSD17B1 protein		 CTD PMID:16151981 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548 		JBrowse link
2,2',4,4'-Tetrabromodiphenyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions EXP 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of ADIPOQ protein CTD PMID:28284726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ADIPOR1 adiponectin receptor 1 increases expression EXP 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ADIPOR1 protein CTD PMID:28284726 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686 		JBrowse link
G ADIPOR2 adiponectin receptor 2 increases expression EXP 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ADIPOR2 protein CTD PMID:28284726 NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235 		JBrowse link
G COMT catechol-O-methyltransferase increases activity EXP 2,2',4,4'-tetrabromodiphenyl ether results in increased activity of COMT protein CTD PMID:22750137 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998 		JBrowse link
G CYP19A3 cytochrome P450 19A3 increases expression
multiple interactions		 EXP 2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of CYP19A1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP19A1 protein
2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]; Fadrozole inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein]		 CTD PMID:23146758 PMID:28284726 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G ESR1 estrogen receptor 1 increases expression EXP 2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR1 protein CTD PMID:24956591 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G ESR2 estrogen receptor 2 increases expression
decreases expression		 EXP 2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR2 mRNA; 2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR2 protein
2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ESR2 mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ESR2 protein		 CTD PMID:24956591 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 increases expression EXP 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of HSD17B1 protein CTD PMID:21871953 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548 		JBrowse link
2,3,7,8-tetrachlorodibenzodioxine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor decreases expression
increases expression
affects localization		 EXP Tetrachlorodibenzodioxin results in decreased expression of AHR mRNA
Tetrachlorodibenzodioxin results in increased expression of AHR protein
Tetrachlorodibenzodioxin affects the localization of AHR protein		 CTD PMID:16431846 PMID:16552988 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression EXP Tetrachlorodibenzodioxin results in increased expression of CCL2 mRNA CTD PMID:19265715 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CTSB cathepsin B decreases expression EXP Tetrachlorodibenzodioxin results in decreased expression of CTSB mRNA CTD PMID:16291828 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression EXP Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA; Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein CTD PMID:16291828 PMID:16431846 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G ESR1 estrogen receptor 1 decreases expression EXP Tetrachlorodibenzodioxin results in decreased expression of ESR1 mRNA; Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein CTD PMID:16431846 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 decreases expression EXP Tetrachlorodibenzodioxin results in decreased expression of SLC5A5 mRNA CTD PMID:16291828 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
3,3',4,4',5-pentachlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor increases expression
multiple interactions
increases activity		 EXP 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR protein
epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein]		 CTD PMID:16552988 PMID:22521609 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G CAV1 caveolin 1 multiple interactions EXP CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; CAV1 mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] CTD PMID:19265715 PMID:20406653 PMID:24709675 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions		 EXP 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein
CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]		 CTD PMID:19265715 PMID:22521609 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CTSB cathepsin B decreases expression EXP 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CTSB mRNA CTD PMID:16291828 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 decreases activity EXP 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP11A1 protein CTD PMID:16151981 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP19A3 cytochrome P450 19A3 increases activity
multiple interactions		 EXP 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP19A1 protein
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein		 CTD PMID:16151981 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression		 EXP epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein		 CTD PMID:16291828 PMID:19608276 PMID:22521609 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 multiple interactions EXP [epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of GSTO1 mRNA CTD PMID:22521609 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 decreases activity EXP 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of HSD17B1 protein CTD PMID:16151981 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:20406653 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:20406653 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA] CTD PMID:22521609 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 EXP 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA
[epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NQO1 mRNA; CAV1 mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA]		 CTD PMID:22521609 PMID:24709675 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 decreases expression EXP 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC5A5 mRNA CTD PMID:16291828 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein		 CTD PMID:20406653 PMID:22521609 PMID:24709675 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
3,3',4,4'-tetrachlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions EXP 3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein; [alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein] CTD PMID:12970578 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G CAV1 caveolin 1 multiple interactions EXP 3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein] CTD PMID:19608276 PMID:20406653 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases secretion
increases expression
multiple interactions		 EXP 3,4,3',4'-tetrachlorobiphenyl results in increased secretion of CCL2 protein
3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA
[2,2'-azobis(2-amidinopropane) results in increased oxidation of Docosahexaenoic Acids] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; [2,2'-azobis(2-amidinopropane) results in increased oxidation of Docosahexaenoic Acids] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 protein]; [2,2'-azobis(2-amidinopropane) results in increased oxidation of Eicosapentaenoic Acid] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; [2,2'-azobis(2-amidinopropane) results in increased oxidation of Eicosapentaenoic Acid] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 protein]; Acetylcysteine inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; sodium borohydride inhibits the reaction [[2,2'-azobis(2-amidinopropane) results in increased oxidation of Docosahexaenoic Acids] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]]; sulforaphane inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; Tretinoin promotes the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 protein]		 CTD PMID:19265715 PMID:21130106 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases activity
increases expression
multiple interactions		 EXP 3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein
3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein
alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein]		 CTD PMID:12970578 PMID:19608276 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK1 protein] CTD PMID:20406653 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK3 protein] CTD PMID:20406653 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions		 EXP 3,4,3',4'-tetrachlorobiphenyl results in increased activity of RELA protein
[2,2'-azobis(2-amidinopropane) results in increased oxidation of Docosahexaenoic Acids] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of RELA protein]		 CTD PMID:21130106 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G SELE selectin E increases expression
multiple interactions		 EXP 3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA]		 CTD PMID:19608276 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G SELP selectin P multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELP mRNA] CTD PMID:19608276 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]
3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein		 CTD PMID:19608276 PMID:20406653 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
3,3',5,5'-tetrabromobisphenol A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 decreases expression
multiple interactions		 EXP tetrabromobisphenol A results in decreased expression of AGO2 protein
[tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of AGO2 protein		 CTD PMID:31266599 NCBI chr 4:2,966,794...3,012,388
Ensembl chr 4:2,919,511...3,015,334 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression EXP tetrabromobisphenol A results in decreased expression of AKT1 mRNA; tetrabromobisphenol A results in decreased expression of AKT1 protein CTD PMID:35665993
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases activity EXP tetrabromobisphenol A results in decreased activity of ATP2A2 protein CTD PMID:17784851 NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,969 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 decreases activity EXP tetrabromobisphenol A results in decreased activity of ATP2A3 protein CTD PMID:17784851 NCBI chr12:49,980,488...50,014,006
Ensembl chr12:49,980,497...50,025,171 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP tetrabromobisphenol A results in increased expression of BAX mRNA; tetrabromobisphenol A results in increased expression of BAX protein
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein]		 CTD PMID:35665993 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP tetrabromobisphenol A results in decreased expression of BCL2 mRNA; tetrabromobisphenol A results in decreased expression of BCL2 protein CTD PMID:35665993 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions		 EXP tetrabromobisphenol A results in increased expression of CASP3 mRNA; tetrabromobisphenol A results in increased expression of CASP3 protein
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 protein]		 CTD PMID:35665993 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CASP8 caspase 8 multiple interactions
decreases expression		 EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 protein]
tetrabromobisphenol A results in decreased expression of CASP8 mRNA; tetrabromobisphenol A results in decreased expression of CASP8 protein		 CTD PMID:35665993 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein]
tetrabromobisphenol A results in increased expression of CASP9 mRNA; tetrabromobisphenol A results in increased expression of CASP9 protein		 CTD PMID:35665993 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007 		JBrowse link
G COX7A2L cytochrome c oxidase subunit 7A2 like increases expression
multiple interactions		 EXP tetrabromobisphenol A results in increased expression of COX7A2L mRNA
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of COX7A2L mRNA]		 CTD PMID:35665993 NCBI chr 3:97,951,115...97,983,309
Ensembl chr 3:97,951,114...97,983,309 		JBrowse link
G DICER1 dicer 1, ribonuclease III decreases expression
multiple interactions		 EXP tetrabromobisphenol A results in decreased expression of DICER1 mRNA; tetrabromobisphenol A results in decreased expression of DICER1 protein
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 protein		 CTD PMID:31266599 NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,365,802...116,411,224 		JBrowse link
G DROSHA drosha ribonuclease III increases expression EXP tetrabromobisphenol A results in increased expression of DROSHA mRNA CTD PMID:31266599 NCBI chr16:17,727,695...17,847,954
Ensembl chr16:17,565,137...17,848,162 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 decreases expression
multiple interactions		 EXP tetrabromobisphenol A results in decreased expression of GPER1 protein
[tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein		 CTD PMID:31266599 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980 		JBrowse link
G LOC100623720 collagen alpha-1(VI) chain increases expression
multiple interactions		 EXP tetrabromobisphenol A results in increased expression of COL6A1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [tetrabromobisphenol A results in increased expression of COL6A1 protein]; tetrabromobisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of COL6A1 protein]		 CTD PMID:31266599 NCBI chr13:208,295,245...208,321,789
Ensembl chr13:208,295,451...208,313,127 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases expression		 EXP [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in increased expression of MAP1LC3B protein
tetrabromobisphenol A results in increased expression of MAP1LC3B protein		 CTD PMID:31266599 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069 		JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL protein]
tetrabromobisphenol A results in increased expression of MLKL mRNA; tetrabromobisphenol A results in increased expression of MLKL protein		 CTD PMID:35665993 NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma decreases expression EXP tetrabromobisphenol A results in decreased expression of PIK3CG mRNA; tetrabromobisphenol A results in decreased expression of PIK3CG protein CTD PMID:35665993 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G PLIN1 perilipin 1 multiple interactions
increases expression		 EXP [tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in increased expression of PLIN1 protein
tetrabromobisphenol A results in increased expression of PLIN1 protein		 CTD PMID:31266599 NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein]
tetrabromobisphenol A results in increased expression of PTEN mRNA; tetrabromobisphenol A results in increased expression of PTEN protein		 CTD PMID:35665993 NCBI chr14:99,929,590...100,021,619 JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression
multiple interactions		 EXP tetrabromobisphenol A results in increased expression of RIPK1 mRNA; tetrabromobisphenol A results in increased expression of RIPK1 protein
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 protein]		 CTD PMID:35665993 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein]
tetrabromobisphenol A results in increased expression of RIPK3 mRNA; tetrabromobisphenol A results in increased expression of RIPK3 protein		 CTD PMID:35665993 NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251 		JBrowse link
G XPO5 exportin 5 multiple interactions
decreases expression		 EXP [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 protein
tetrabromobisphenol A results in decreased expression of XPO5 protein		 CTD PMID:31266599 NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,531,919...38,569,582 		JBrowse link
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5AP arachidonate 5-lipoxygenase activating protein multiple interactions EXP MK-886 inhibits the reaction [aristolochic acid I results in increased expression of ALOX5AP protein] CTD PMID:21658425 NCBI chr11:7,371,328...7,438,111
Ensembl chr11:7,411,644...7,438,108 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP MK-886 inhibits the reaction [aristolochic acid I results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:21658425 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT1 sirtuin 1 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]] CTD PMID:36549457 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
acifluorfen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPOX protoporphyrinogen oxidase decreases activity EXP acifluorfen results in decreased activity of PPOX protein CTD PMID:7697001 NCBI chr 4:89,277,984...89,288,946
Ensembl chr 4:89,284,500...89,288,902 		JBrowse link
ageladine A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSNK1A1 casein kinase 1 alpha 1 decreases activity
affects activity		 EXP Ageladine A analog results in decreased activity of CSNK1A1 protein
Ageladine A affects the activity of CSNK1A1 protein		 CTD PMID:21413800 NCBI chr 2:150,612,845...150,662,431
Ensembl chr 2:150,612,077...150,662,284 		JBrowse link
alachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C49 cytochrome P450 2C49 decreases response to substance EXP CYP2C49 protein results in decreased susceptibility to alachlor CTD PMID:16315095 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
amiloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator increases activity EXP Amiloride results in increased activity of CFTR protein CTD PMID:15246976 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G PLAU plasminogen activator, urokinase multiple interactions EXP Amiloride inhibits the reaction [[Asbestos, Crocidolite results in increased activity of PLAU protein] which results in increased cleavage of PLG protein]; Amiloride inhibits the reaction [[Asbestos, Serpentine results in increased activity of PLAU protein] which results in increased cleavage of PLG protein] CTD PMID:9853007 NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172 		JBrowse link
G PLG plasminogen multiple interactions EXP Amiloride inhibits the reaction [[Asbestos, Crocidolite results in increased activity of PLAU protein] which results in increased cleavage of PLG protein]; Amiloride inhibits the reaction [[Asbestos, Serpentine results in increased activity of PLAU protein] which results in increased cleavage of PLG protein]; Amiloride inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of PLG protein]; Amiloride inhibits the reaction [Asbestos, Serpentine results in increased cleavage of PLG protein] CTD PMID:9853007 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions EXP Amiloride promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA] CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
ammonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]] CTD PMID:34520801 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687 		JBrowse link
G SOX5 SRY-box transcription factor 5 multiple interactions EXP Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]] CTD PMID:34520801 NCBI chr 5:49,159,950...50,166,463
Ensembl chr 5:49,504,551...50,161,558 		JBrowse link
betamethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMOX2 heme oxygenase 2 increases expression EXP Betamethasone results in increased expression of HMOX2 protein CTD PMID:11698254 NCBI chr 3:37,829,044...37,868,163
Ensembl chr 3:37,831,439...37,868,128 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Betamethasone results in decreased expression of PTGS2 protein CTD PMID:11698254 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
bezafibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 increases expression
increases secretion		 EXP Bezafibrate results in increased expression of APOA1 mRNA
Bezafibrate results in increased secretion of APOA1 protein		 CTD PMID:16530456 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Bezafibrate inhibits the reaction [Cisplatin affects the localization of BAX protein] CTD PMID:16316343 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression EXP Bezafibrate results in increased expression of BCL2 CTD PMID:16316343 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP Bezafibrate inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:16316343 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP Bezafibrate inhibits the reaction [Cisplatin affects the localization of CYCS protein] CTD PMID:16316343 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G LIPG lipase G, endothelial type decreases expression EXP Bezafibrate results in decreased expression of LIPG mRNA; Bezafibrate results in decreased expression of LIPG protein CTD PMID:15953354 NCBI chr 1:99,081,940...99,110,671
Ensembl chr 1:99,081,938...99,110,874 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP Bezafibrate inhibits the reaction [[Cisplatin results in decreased activity of PPARA protein] which results in increased abundance of Fatty Acids, Nonesterified]; Bezafibrate inhibits the reaction [Cisplatin results in decreased activity of PPARA protein] CTD PMID:16316343 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G SCARB1 scavenger receptor class B member 1 affects localization
increases expression		 EXP Bezafibrate affects the localization of SCARB1 protein
Bezafibrate results in increased expression of SCARB1 mRNA		 CTD PMID:16530456 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
bifenthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 affects phosphorylation EXP bifenthrin affects the phosphorylation of AKT1 protein CTD PMID:33901951
G CCL14 C-C motif chemokine ligand 14 decreases expression EXP bifenthrin results in decreased expression of CCL14 mRNA CTD PMID:33901951 NCBI chr12:39,611,887...39,616,050
Ensembl chr12:39,611,868...39,616,159 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 decreases expression EXP bifenthrin results in decreased expression of CCL4 mRNA CTD PMID:33901951 NCBI chr12:39,479,190...39,480,511
Ensembl chr12:39,478,882...39,481,082 		JBrowse link
G CCND1 cyclin D1 decreases expression EXP bifenthrin results in decreased expression of CCND1 mRNA CTD PMID:33901951 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CCNE1 cyclin E1 decreases expression EXP bifenthrin results in decreased expression of CCNE1 mRNA CTD PMID:33901951 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,366 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 decreases expression EXP bifenthrin results in decreased expression of CX3CL1 mRNA CTD PMID:33901951 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP bifenthrin results in increased expression of DDIT3 protein CTD PMID:33901951 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP bifenthrin results in increased phosphorylation of EIF2S1 protein CTD PMID:33901951 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP bifenthrin results in increased expression of HSPA5 protein CTD PMID:33901951 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G LEPR leptin receptor decreases expression EXP bifenthrin results in decreased expression of LEPR mRNA CTD PMID:33901951 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation EXP bifenthrin results in increased phosphorylation of MAPK1 protein CTD PMID:33901951 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation EXP bifenthrin results in increased phosphorylation of MAPK3 protein CTD PMID:33901951 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation EXP bifenthrin results in increased phosphorylation of MAPK8 protein CTD PMID:33901951 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression EXP bifenthrin results in decreased expression of PCNA protein CTD PMID:33901951 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744 		JBrowse link
G RARB retinoic acid receptor beta decreases expression EXP bifenthrin results in decreased expression of RARB mRNA CTD PMID:33901951 NCBI chr13:12,336,387...12,507,688
Ensembl chr13:12,336,972...12,507,680 		JBrowse link
G RPS6 ribosomal protein S6 increases phosphorylation EXP bifenthrin results in increased phosphorylation of RPS6 protein CTD PMID:33901951 NCBI chr 1:203,444,360...203,447,643
Ensembl chr 1:203,444,450...203,451,468 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 affects phosphorylation EXP bifenthrin affects the phosphorylation of RPS6KB1 protein CTD PMID:33901951 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
bis(2-chloroethyl) sulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin increases expression EXP Mustard Gas results in increased expression of ADM mRNA CTD PMID:18988085 NCBI chr 2:49,229,223...49,231,521
Ensembl chr 2:49,229,223...49,231,866 		JBrowse link
G AIF1 allograft inflammatory factor 1 increases expression EXP Mustard Gas results in increased expression of AIF1 mRNA CTD PMID:18988085 NCBI chr 7:23,711,752...23,731,191
Ensembl chr 7:23,726,787...23,731,671 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane increases expression EXP Mustard Gas results in increased expression of ANPEP mRNA CTD PMID:18988085 NCBI chr 7:55,351,081...55,373,856
Ensembl chr 7:55,351,087...55,373,881 		JBrowse link
G ANXA1 annexin A1 increases expression EXP Mustard Gas results in increased expression of ANXA1 mRNA CTD PMID:18988085 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279 		JBrowse link
G ARG1 arginase 1 increases expression EXP Mustard Gas results in increased expression of ARG1 mRNA CTD PMID:18988085 NCBI chr 1:32,006,035...32,028,983
Ensembl chr 1:32,006,046...32,028,988 		JBrowse link
G ATF2 activating transcription factor 2 affects expression EXP Mustard Gas affects the expression of ATF2 mRNA CTD PMID:18988085 NCBI chr15:80,984,969...81,076,573
Ensembl chr15:80,985,126...81,081,014 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP Mustard Gas results in decreased expression of BCL2 protein CTD PMID:9302645 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 increases expression EXP Mustard Gas results in increased expression of BIRC6 mRNA CTD PMID:18988085 NCBI chr 3:107,012,967...107,269,370
Ensembl chr 3:107,012,986...107,269,477 		JBrowse link
G BMP5 bone morphogenetic protein 5 decreases expression EXP Mustard Gas results in decreased expression of BMP5 mRNA CTD PMID:18988085 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470 		JBrowse link
G C2 complement C2 increases expression EXP Mustard Gas results in increased expression of C2 mRNA CTD PMID:18988085 NCBI chr 7:24,020,590...24,034,042
Ensembl chr 7:23,995,982...24,033,930 		JBrowse link
G C3 complement C3 increases expression EXP Mustard Gas results in increased expression of C3 mRNA CTD PMID:18988085 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228 		JBrowse link
G C7 complement C7 increases expression EXP Mustard Gas results in increased expression of C7 mRNA CTD PMID:18988085 NCBI chr16:25,846,860...25,902,707
Ensembl chr16:25,846,860...25,903,980 		JBrowse link
G CAPNS1 calpain small subunit 1 increases expression EXP Mustard Gas results in increased expression of CAPNS1 mRNA CTD PMID:18988085 NCBI chr 6:45,511,410...45,518,610
Ensembl chr 6:45,511,295...45,518,610 		JBrowse link
G CASP3 caspase 3 increases expression EXP Mustard Gas results in increased expression of CASP3 mRNA CTD PMID:18988085 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 increases expression EXP Mustard Gas results in increased expression of CCL19 mRNA CTD PMID:18988085 NCBI chr10:32,110,366...32,112,529
Ensembl chr10:32,110,065...32,112,734 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression EXP Mustard Gas results in increased expression of CCL2 mRNA CTD PMID:18988085 PMID:27617619 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression EXP Mustard Gas results in increased expression of CCL5 mRNA CTD PMID:18988085 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118 		JBrowse link
G CCN1 cellular communication network factor 1 increases expression EXP Mustard Gas results in increased expression of CCN1 mRNA CTD PMID:27617619 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,407...130,395,150 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression EXP Mustard Gas results in increased expression of CCN2 mRNA CTD PMID:27617619 NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,674,394...31,677,691 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 increases expression EXP Mustard Gas results in increased expression of CCR1 mRNA CTD PMID:18988085 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 decreases expression EXP Mustard Gas results in decreased expression of CCR5 mRNA CTD PMID:27617619 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP Mustard Gas results in increased expression of CDKN1A mRNA CTD PMID:27617619 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761 		JBrowse link
G CFB complement factor B increases expression EXP Mustard Gas results in increased expression of BF mRNA CTD PMID:18988085 NCBI chr 7:24,034,077...24,040,523
Ensembl chr 7:24,033,740...24,041,179 		JBrowse link
G CLDN1 claudin 1 decreases expression EXP Mustard Gas results in decreased expression of CLDN1 mRNA CTD PMID:18988085 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657 		JBrowse link
G CLU clusterin increases expression EXP Mustard Gas results in increased expression of CLU mRNA CTD PMID:18988085 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G CTNNA3 catenin alpha 3 decreases expression EXP Mustard Gas results in decreased expression of CTNNA3 mRNA CTD PMID:18988085 NCBI chr14:69,195,231...70,974,543
Ensembl chr14:69,195,961...70,938,204 		JBrowse link
G CXCL2 chemokine (C-X-C motif) ligand 2 increases expression EXP Mustard Gas results in increased expression of CXCL2 mRNA CTD PMID:18988085 NCBI chr 8:70,157,253...70,159,145
Ensembl chr 8:70,157,214...70,159,138 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Mustard Gas results in increased expression of CXCL8 mRNA CTD PMID:12481301 PMID:18988085 PMID:27617619 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression EXP Mustard Gas results in increased expression of CXCR4 mRNA CTD PMID:18988085 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232 		JBrowse link
G EGR1 early growth response 1 increases expression EXP Mustard Gas results in increased expression of EGR1 mRNA CTD PMID:18988085 PMID:27617619 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G EPHA4 EPH receptor A4 decreases expression EXP Mustard Gas results in decreased expression of EPHA4 mRNA CTD PMID:18988085 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,816...123,503,126 		JBrowse link
G FBXO32 F-box protein 32 decreases expression EXP Mustard Gas results in decreased expression of FBXO32 mRNA CTD PMID:27617619 NCBI chr 4:15,895,875...15,925,929
Ensembl chr 4:15,895,689...15,930,931 		JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) increases expression EXP Mustard Gas results in increased expression of FCNB mRNA CTD PMID:18988085 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970 		JBrowse link
G FGF2 fibroblast growth factor 2 increases expression EXP Mustard Gas results in increased expression of FGF2 mRNA CTD PMID:27617619 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 decreases expression EXP Mustard Gas results in decreased expression of FGFR2 mRNA CTD PMID:18988085 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Mustard Gas results in increased expression of FOS mRNA CTD PMID:18988085 PMID:27617619 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G FXYD3 FXYD domain containing ion transport regulator 3 decreases expression EXP Mustard Gas results in decreased expression of FXYD3 mRNA CTD PMID:18988085 NCBI chr 6:44,647,771...44,654,377
Ensembl chr 6:44,647,466...44,654,374 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP Mustard Gas results in increased expression of GADD45A mRNA CTD PMID:18988085 NCBI chr 6:144,940,702...144,944,089
Ensembl chr 6:144,940,697...144,944,089 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Mustard Gas results in increased expression of GAPDH mRNA CTD PMID:18988085 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 increases expression EXP Mustard Gas results in increased expression of GUCY1B1 mRNA CTD PMID:18988085 NCBI chr 8:44,544,364...44,604,690
Ensembl chr 8:44,544,179...44,604,687 		JBrowse link
G HBEGF heparin binding EGF like growth factor increases expression EXP Mustard Gas results in increased expression of HBEGF mRNA CTD PMID:27617619 NCBI chr 2:142,102,455...142,115,192
Ensembl chr 2:142,102,458...142,115,174 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Mustard Gas results in increased expression of HMOX1 mRNA CTD PMID:18988085
G HSPA1L heat shock protein family A (Hsp70) member 1 like increases expression EXP Mustard Gas results in increased expression of HSPA1L mRNA CTD PMID:18988085 NCBI chr 7:23,909,960...23,938,678
Ensembl chr 7:23,909,960...23,914,629 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Mustard Gas results in increased expression of ICAM1 mRNA CTD PMID:18988085 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IGF1 insulin like growth factor 1 increases expression EXP Mustard Gas results in increased expression of IGF1 mRNA CTD PMID:18988085 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 decreases expression EXP Mustard Gas results in decreased expression of IGFBP5 mRNA CTD PMID:18988085 NCBI chr15:118,861,816...118,877,787
Ensembl chr15:118,857,625...118,878,120 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 increases expression EXP Mustard Gas results in increased expression of IL1R1 mRNA CTD PMID:18988085 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,915...52,288,485 		JBrowse link
G IL23A interleukin 23 subunit alpha decreases expression EXP Mustard Gas results in decreased expression of IL23A mRNA CTD PMID:27617619 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G IL4R interleukin 4 receptor decreases expression EXP Mustard Gas results in decreased expression of IL4R mRNA CTD PMID:18988085 NCBI chr 3:19,526,343...19,576,792
Ensembl chr 3:19,523,564...19,576,544 		JBrowse link
G IL6 interleukin 6 increases expression EXP Mustard Gas results in increased expression of IL6 mRNA CTD PMID:12481301 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G INHCA inhibitor of carbonic anhydrase decreases expression EXP Mustard Gas results in decreased expression of PICA mRNA CTD PMID:18988085 NCBI chr13:74,862,502...74,907,059 JBrowse link
G ITGA6 integrin subunit alpha 6 affects expression EXP Mustard Gas affects the expression of ITGA6 protein CTD PMID:9285538 NCBI chr15:78,504,108...78,591,779
Ensembl chr15:78,504,078...78,591,777 		JBrowse link
G ITGB2 integrin subunit beta 2 increases expression EXP Mustard Gas results in increased expression of ITGB2 mRNA CTD PMID:18988085 NCBI chr13:207,514,281...207,544,108
Ensembl chr13:207,512,950...207,544,107 		JBrowse link
G ITGB4 integrin subunit beta 4 affects expression EXP Mustard Gas affects the expression of ITGB4 protein CTD PMID:9285538 NCBI chr12:5,651,292...5,685,601
Ensembl chr12:5,651,292...5,685,611 		JBrowse link
G LAMC2 laminin subunit gamma 2 decreases expression EXP Mustard Gas results in decreased expression of LAMC2 protein CTD PMID:9302645 NCBI chr 9:124,427,545...124,499,672
Ensembl chr 9:124,435,807...124,495,351 		JBrowse link
G LDHA lactate dehydrogenase A increases expression EXP Mustard Gas results in increased expression of LDHA mRNA CTD PMID:18988085 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression EXP Mustard Gas results in increased expression of IL1B mRNA CTD PMID:12481301
G LTF lactotransferrin increases expression EXP Mustard Gas results in increased expression of PLF mRNA CTD PMID:18988085 NCBI chr13:29,413,886...29,445,751
Ensembl chr13:29,413,886...29,445,739 		JBrowse link
G MMP9 matrix metallopeptidase 9 increases expression EXP Mustard Gas results in increased expression of MMP9 mRNA CTD PMID:12481301 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MT3 metallothionein 3 decreases expression EXP Mustard Gas results in decreased expression of MT3 mRNA CTD PMID:18988085 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Mustard Gas results in increased expression of MYC mRNA CTD PMID:27617619 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NPPB natriuretic peptide B increases expression EXP Mustard Gas results in increased expression of NPPB mRNA CTD PMID:27617619 NCBI chr 6:71,930,374...71,931,843
Ensembl chr 6:71,930,382...71,932,254 		JBrowse link
G NR2F2 nuclear receptor subfamily 2 group F member 2 increases expression EXP Mustard Gas results in increased expression of NR2F2 mRNA CTD PMID:18988085 NCBI chr 7:83,076,119...83,090,250
Ensembl chr 7:83,076,124...83,090,535 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 increases expression EXP Mustard Gas results in increased expression of NR4A3 mRNA CTD PMID:18988085 NCBI chr 1:241,569,867...241,611,735
Ensembl chr 1:241,570,010...241,611,727 		JBrowse link
G OSGIN1 oxidative stress induced growth inhibitor 1 increases expression EXP Mustard Gas results in increased expression of OSGIN1 mRNA CTD PMID:27617619 NCBI chr 6:4,642,762...4,656,113
Ensembl chr 6:4,642,764...4,653,487 		JBrowse link
G PCNA proliferating cell nuclear antigen increases expression EXP Mustard Gas results in increased expression of PCNA protein CTD PMID:9302645 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha increases expression EXP Mustard Gas results in increased expression of PDGFRA mRNA CTD PMID:18988085 NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,441 		JBrowse link
G PLAU plasminogen activator, urokinase increases expression EXP Mustard Gas results in increased expression of PLAU mRNA CTD PMID:18988085 NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor increases expression EXP Mustard Gas results in increased expression of PLAUR mRNA CTD PMID:18988085 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418 		JBrowse link
G POU2F3 POU class 2 homeobox 3 decreases expression EXP Mustard Gas results in decreased expression of POU2F3 mRNA CTD PMID:18988085 NCBI chr 9:47,376,852...47,458,265
Ensembl chr 9:47,376,750...47,460,165 		JBrowse link
G PPBP pro-platelet basic protein increases expression EXP Mustard Gas results in increased expression of PF4 mRNA CTD PMID:18988085 NCBI chr 8:70,021,468...70,022,490
Ensembl chr 8:70,021,439...70,023,964 		JBrowse link
G PPRC1 PPARG related coactivator 1 increases expression EXP Mustard Gas results in increased expression of PPRC1 mRNA CTD PMID:27617619 NCBI chr14:113,137,012...113,152,828
Ensembl chr14:113,137,037...113,152,831 		JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 decreases expression EXP Mustard Gas results in decreased expression of RAPGEF4 mRNA CTD PMID:18988085 NCBI chr15:78,773,270...79,094,490
Ensembl chr15:78,773,266...79,095,040 		JBrowse link
G RHBG Rh family B glycoprotein decreases expression EXP Mustard Gas results in decreased expression of RHBG mRNA CTD PMID:18988085 NCBI chr 4:93,694,259...93,708,055
Ensembl chr 4:93,694,266...93,707,865 		JBrowse link
G SCARB2 scavenger receptor class B member 2 increases expression EXP Mustard Gas results in increased expression of SCARB2 mRNA CTD PMID:18988085 NCBI chr 8:71,838,395...71,910,461
Ensembl chr 8:71,838,397...71,940,607 		JBrowse link
G SELE selectin E increases expression EXP Mustard Gas results in increased expression of SELE mRNA CTD PMID:18988085 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G SERPINE1 serpin family E member 1 increases expression EXP Mustard Gas results in increased expression of SERPINE1 mRNA CTD PMID:27617619 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SHAS2 hyaluronan synthase 2 increases expression EXP Mustard Gas results in increased expression of SHAS2 mRNA CTD PMID:18988085 NCBI chr 4:17,583,154...17,613,524
Ensembl chr 4:17,596,492...17,615,480 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 decreases expression EXP Mustard Gas results in decreased expression of SLC5A1 mRNA CTD PMID:18988085 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression EXP Mustard Gas results in increased expression of SOD2 mRNA CTD PMID:18988085 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression EXP Mustard Gas results in increased expression of SPP1 mRNA CTD PMID:18988085 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G TBXAS1 thromboxane A synthase 1 increases expression EXP Mustard Gas results in increased expression of TBXAS1 mRNA CTD PMID:18988085 NCBI chr18:9,717,291...9,886,699
Ensembl chr18:9,717,294...9,886,681 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP Mustard Gas results in increased expression of TIMP1 mRNA CTD PMID:18988085 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,296 		JBrowse link
G TLR2 toll like receptor 2 increases expression EXP Mustard Gas results in increased expression of TLR2 mRNA CTD PMID:18988085 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR4 toll like receptor 4 increases expression EXP Mustard Gas results in increased expression of TLR4 mRNA CTD PMID:18988085 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TNC tenascin C increases expression EXP Mustard Gas results in increased expression of TNC mRNA CTD PMID:18988085 NCBI chr 1:255,533,235...255,630,381
Ensembl chr 1:255,533,238...255,630,376 		JBrowse link
G TNF tumor necrosis factor increases expression EXP Mustard Gas results in increased expression of TNF mRNA CTD PMID:12481301 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TNXB tenascin XB decreases expression EXP Mustard Gas results in decreased expression of TNXB mRNA CTD PMID:18988085 NCBI chr 7:24,088,873...24,155,815
Ensembl chr 7:24,088,873...24,150,596 		JBrowse link
G TP53 tumor protein p53 increases expression EXP Mustard Gas results in increased expression of TP53 protein CTD PMID:9302645 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G TXN thioredoxin increases expression EXP Mustard Gas results in increased expression of TXN mRNA CTD PMID:18988085 NCBI chr 1:251,264,180...251,278,000
Ensembl chr 1:251,263,175...251,277,988 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase decreases expression EXP Mustard Gas results in decreased expression of TYRO3 mRNA CTD PMID:18988085 NCBI chr 1:129,811,540...129,829,395
Ensembl chr 1:129,811,544...129,829,014 		JBrowse link
G UGP2 UDP-glucose pyrophosphorylase 2 increases expression EXP Mustard Gas results in increased expression of UGP2 mRNA CTD PMID:18988085 NCBI chr 3:77,975,450...78,032,471
Ensembl chr 3:77,975,441...78,031,703 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 decreases expression EXP Mustard Gas results in decreased expression of VAV3 mRNA CTD PMID:18988085 NCBI chr 4:111,825,071...112,202,833
Ensembl chr 4:111,824,896...112,202,825 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression EXP Mustard Gas results in increased expression of VCAM1 mRNA CTD PMID:18988085 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon increases expression EXP Mustard Gas results in increased expression of YWHAE mRNA CTD PMID:18988085 NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,745...47,645,301 		JBrowse link
calcium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPEP glutamyl aminopeptidase multiple interactions EXP Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] CTD PMID:8141778 NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein CTD PMID:26582256 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
capsazepine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPV1 transient receptor potential cation channel subfamily V member 1 multiple interactions EXP capsazepine inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]] CTD PMID:18230619 NCBI chr12:49,676,536...49,709,634
Ensembl chr12:49,677,291...49,713,977 		JBrowse link
chloroquine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions EXP Chloroquine promotes the reaction [ochratoxin A results in increased cleavage of CASP3 protein] CTD PMID:30287338 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 multiple interactions EXP Chloroquine inhibits the reaction [CPG-oligonucleotide results in increased expression of HSPD1 protein] CTD PMID:17727805 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IFIT1 mRNA] CTD PMID:27079946 NCBI chr14:101,237,403...101,249,486
Ensembl chr14:101,237,571...101,249,498 		JBrowse link
G IFNB1 interferon beta 1 multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IFNB1 mRNA] CTD PMID:27079946 NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495 		JBrowse link
G IFNG interferon gamma multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IFNG mRNA] CTD PMID:27079946 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL12B interleukin 12B multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IL12B mRNA] CTD PMID:27079946 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,143,268...64,158,929 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IL6 mRNA] CTD PMID:27079946 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IRF7 interferon regulatory factor 7 multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IRF7 mRNA] CTD PMID:27079946 NCBI chr 2:372,235...375,572
Ensembl chr 2:372,238...375,378 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of ISG15 mRNA] CTD PMID:27079946 NCBI chr 6:63,363,201...63,364,211
Ensembl chr 6:63,363,173...63,364,208 		JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of IL1B mRNA] CTD PMID:27079946
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP Chloroquine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein] CTD PMID:30287338 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP Chloroquine inhibits the reaction [SZU-101 results in increased expression of RELA protein] CTD PMID:27079946 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G SQSTM1 sequestosome 1 increases expression
multiple interactions		 EXP Chloroquine results in increased expression of SQSTM1 protein
Chloroquine inhibits the reaction [ochratoxin A results in decreased expression of SQSTM1 protein]		 CTD PMID:30287338 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938 		JBrowse link
G TLR7 toll like receptor 7 multiple interactions EXP Chloroquine affects the localization of and results in decreased activity of TLR7 protein CTD PMID:27079946 NCBI chr  X:9,573,178...9,576,987 JBrowse link
chlorotoluron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B decreases response to substance EXP CYP2B6B protein results in decreased susceptibility to chlortoluron CTD PMID:16315095 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334 		JBrowse link
G CYP2C49 cytochrome P450 2C49 decreases response to substance EXP CYP2C49 protein results in decreased susceptibility to chlortoluron CTD PMID:16315095 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
chlorpromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAO D-amino acid oxidase decreases activity EXP Chlorpromazine results in decreased activity of DAO protein CTD PMID:18615285 NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,931,541...41,950,633 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 increases oxidation EXP FMO1 protein results in increased oxidation of Chlorpromazine CTD PMID:6439199 NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076 		JBrowse link
chlorpyrifos-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEH acylaminoacyl-peptide hydrolase decreases activity EXP chlorpyrifos-methyl results in decreased activity of APEH protein CTD PMID:10953051 NCBI chr13:32,205,863...32,214,517
Ensembl chr13:32,205,609...32,214,518 		JBrowse link
chlortetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions
increases uptake		 EXP Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730 		JBrowse link
ciprofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNF tumor necrosis factor multiple interactions EXP [ciprofibrate co-treated with Zinc] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of TNF protein] CTD PMID:15226458 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
clofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 increases expression EXP Clofibrate results in increased expression of ACO1 mRNA CTD PMID:17363680 NCBI chr10:33,937,833...34,001,895
Ensembl chr10:33,937,833...34,001,900 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 increases expression EXP Clofibrate results in increased expression of ACOX1 mRNA CTD PMID:16896063 PMID:17437637 NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546 		JBrowse link
G AGT angiotensinogen multiple interactions EXP Clofibrate inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein] CTD PMID:17105827 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G ALB albumin decreases expression EXP Clofibrate results in decreased expression of ALB mRNA CTD PMID:16896063 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP Clofibrate results in increased expression of BAX mRNA CTD PMID:17437637 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP Clofibrate results in decreased expression of BCL2L1 mRNA CTD PMID:17437637 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G CAT catalase increases expression EXP Clofibrate results in increased expression of CAT mRNA CTD PMID:17437637 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A increases expression EXP Clofibrate results in increased expression of CPT1A mRNA CTD PMID:16896063 PMID:17363680 NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,911 		JBrowse link
G CTSB cathepsin B increases expression EXP Clofibrate results in increased expression of CTSB mRNA CTD PMID:16896063 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G DIO2 iodothyronine deiodinase 2 decreases expression EXP Clofibrate results in decreased expression of DIO2 mRNA CTD PMID:16896063 NCBI chr 7:103,096,414...103,110,749
Ensembl chr 7:103,096,433...103,323,258 		JBrowse link
G EDN1 endothelin 1 decreases expression
multiple interactions		 EXP Clofibrate results in decreased expression of EDN1 protein
Clofibrate inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein]; Clofibrate inhibits the reaction [KNG1 protein modified form results in increased expression of EDN1 protein]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein]; Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein]		 CTD PMID:17105827 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G FABP1 fatty acid binding protein 1 increases expression EXP Clofibrate results in increased expression of FABP1 mRNA CTD PMID:17363680 NCBI chr 3:57,850,511...57,854,966
Ensembl chr 3:57,850,499...57,854,956 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression EXP Clofibrate results in decreased expression of GPX1 mRNA CTD PMID:17437637 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Clofibrate results in increased expression of HMGCS2 mRNA CTD PMID:17363680 NCBI chr 4:101,420,941...101,440,302
Ensembl chr 4:101,420,872...101,438,126 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Clofibrate results in increased expression of JUN mRNA CTD PMID:17437637 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G KNG1 kininogen 1 multiple interactions EXP Clofibrate inhibits the reaction [KNG1 protein modified form results in increased expression of EDN1 protein] CTD PMID:17105827 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,340...124,557,958 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Clofibrate results in increased expression of MYC mRNA CTD PMID:17437637 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NOS3 nitric oxide synthase 3 increases expression
multiple interactions		 EXP Clofibrate results in increased expression of NOS3 protein
calphostin C inhibits the reaction [Clofibrate results in increased expression of NOS3 protein]		 CTD PMID:17105827 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression
multiple interactions		 EXP Clofibrate results in increased expression of PPARA; Clofibrate results in increased expression of PPARA protein
calphostin C inhibits the reaction [Clofibrate results in increased expression of PPARA protein]; calphostin C inhibits the reaction [Clofibrate results in increased expression of PPARA]; Tetradecanoylphorbol Acetate inhibits the reaction [Clofibrate results in increased expression of PPARA]		 CTD PMID:17105827 PMID:20568414 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G SCD stearoyl-CoA desaturase increases expression EXP Clofibrate results in increased expression of SCD mRNA CTD PMID:17363680 NCBI chr14:111,461,560...111,478,033
Ensembl chr14:111,461,569...111,478,020 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 increases expression EXP Clofibrate results in increased expression of SLC5A5 mRNA CTD PMID:16896063 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression EXP Clofibrate results in increased expression of SOD1 mRNA CTD PMID:17437637 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G THRA thyroid hormone receptor alpha decreases expression EXP Clofibrate results in decreased expression of THRA mRNA CTD PMID:16896063 NCBI chr12:22,270,506...22,296,684
Ensembl chr12:22,270,062...22,296,618 		JBrowse link
G TNF tumor necrosis factor decreases expression EXP Clofibrate results in decreased expression of TNF mRNA CTD PMID:17437637 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TPO thyroid peroxidase increases expression EXP Clofibrate results in increased expression of TPO mRNA CTD PMID:16896063 NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208 		JBrowse link
G TSHR thyroid stimulating hormone receptor increases expression EXP Clofibrate results in increased expression of TSHR mRNA CTD PMID:16896063 NCBI chr 7:103,768,260...103,925,777
Ensembl chr 7:103,768,296...103,925,922 		JBrowse link
G TTR transthyretin decreases expression EXP Clofibrate results in decreased expression of TTR mRNA CTD PMID:16896063 NCBI chr 6:115,496,338...115,503,974
Ensembl chr 6:115,496,326...115,503,977 		JBrowse link
clorgyline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAOA monoamine oxidase A decreases activity EXP Clorgyline analog results in decreased activity of MAOA protein CTD PMID:33359020 NCBI chr  X:38,930,452...39,006,220 JBrowse link
cobalt dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 affects binding EXP cobaltous chloride binds to AOC1 protein CTD PMID:16842785 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression EXP cobaltous chloride results in increased expression of HSP90B1 mRNA CTD PMID:17464326 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP cobaltous chloride results in increased expression of HSPA5 mRNA CTD PMID:17464326 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
colforsin daropate hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 decreases activity EXP Colforsin results in decreased activity of ADCYAP1 protein alternative form CTD PMID:16847435 NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294 		JBrowse link
G ATP7B ATPase copper transporting beta multiple interactions EXP Colforsin inhibits the reaction [Copper binds to ATP7B protein] CTD PMID:21084060 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064 		JBrowse link
G CFTR CF transmembrane conductance regulator increases activity EXP Colforsin results in increased activity of CFTR protein CTD PMID:15246976 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] CTD PMID:17680988 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728 		JBrowse link
copper(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 increases activity EXP cupric chloride results in increased activity of AOC1 protein CTD PMID:16842785 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974 		JBrowse link
crizotinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NTRK1 neurotrophic receptor tyrosine kinase 1 decreases activity EXP Crizotinib results in decreased activity of NTRK1 protein CTD PMID:21812414 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,255,981 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 decreases activity EXP Crizotinib results in decreased activity of NTRK2 protein CTD PMID:21812414 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,405...30,429,882 		JBrowse link
DDE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 decreases expression
multiple interactions		 EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of CYP11A1 mRNA
Dichlorodiphenyl Dichloroethylene inhibits the reaction [Cholera Toxin results in increased expression of CYP11A1 mRNA]		 CTD PMID:11226075 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP19A3 cytochrome P450 19A3 increases activity EXP Dichlorodiphenyl Dichloroethylene results in increased activity of CYP19A1 protein CTD PMID:18195494 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
dexamethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA CTD PMID:30481989 NCBI chr 6:79,589,695...79,649,646
Ensembl chr 6:79,589,045...79,649,644 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BCL2L1 mRNA CTD PMID:30481989 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Troglitazone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CASP3 mRNA CTD PMID:30481989 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha increases expression
multiple interactions		 EXP Dexamethasone results in increased expression of CEBPA mRNA
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA]		 CTD PMID:11225715 PMID:30481989 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA CTD PMID:30481989 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] CTD PMID:30481989 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 increases expression EXP Dexamethasone results in increased expression of CYP17A1 CTD PMID:19852296 NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041 		JBrowse link
G FABP4 fatty acid binding protein 4 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] CTD PMID:30481989 NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA] CTD PMID:30481989 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033 		JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA] CTD PMID:30481989 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G IRS1 insulin receptor substrate 1 decreases expression EXP Dexamethasone results in decreased expression of IRS1 mRNA CTD PMID:19852296 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,307,284 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
multiple interactions		 EXP Dexamethasone results in increased expression of PPARG
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]		 CTD PMID:19852296 PMID:30481989 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA CTD PMID:30481989 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 decreases expression EXP Dexamethasone results in decreased expression of SLC2A4 mRNA; Dexamethasone results in decreased expression of SLC2A4 protein CTD PMID:19852296 NCBI chr12:52,628,746...52,634,965
Ensembl chr12:52,628,450...52,634,967 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] CTD PMID:30481989 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
dichlorine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type decreases expression EXP Chlorine results in decreased expression of ALOX12 mRNA CTD PMID:22533443 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression EXP Chlorine results in increased expression of CCL2 mRNA CTD PMID:22533443 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 increases expression EXP Chlorine results in increased expression of CCR1 mRNA CTD PMID:22533443 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Chlorine results in increased expression of CXCL8 mRNA CTD PMID:22533443 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G EDN1 endothelin 1 increases expression EXP Chlorine results in increased expression of EDN1 protein CTD PMID:16625121 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 decreases expression EXP Chlorine results in decreased expression of FGFR2 mRNA CTD PMID:22533443 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Chlorine results in increased expression of FOS mRNA CTD PMID:22533443 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Chlorine results in increased expression of ICAM1 mRNA CTD PMID:22533443 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IL1A interleukin 1 alpha decreases expression EXP Chlorine results in decreased expression of IL1A mRNA CTD PMID:22533443 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 increases expression EXP Chlorine results in increased expression of IL1R1 mRNA CTD PMID:22533443 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,915...52,288,485 		JBrowse link
G IL6 interleukin 6 increases expression EXP Chlorine results in increased expression of IL6 mRNA CTD PMID:22533443 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression EXP Chlorine results in increased expression of IL1B mRNA CTD PMID:22533443
G SELE selectin E increases expression EXP Chlorine results in increased expression of SELE mRNA CTD PMID:22533443 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A increases expression EXP Chlorine results in increased expression of TNFRSF12A mRNA CTD PMID:22533443 NCBI chr 3:39,166,288...39,168,294
Ensembl chr 3:39,166,298...39,168,302 		JBrowse link
dichlorvos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase decreases activity EXP Dichlorvos results in decreased activity of ACHE protein CTD PMID:21467751 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605 		JBrowse link
G APEH acylaminoacyl-peptide hydrolase decreases activity EXP Dichlorvos results in decreased activity of APEH protein CTD PMID:10953051 NCBI chr13:32,205,863...32,214,517
Ensembl chr13:32,205,609...32,214,518 		JBrowse link
G BCHE butyrylcholinesterase decreases activity EXP Dichlorvos results in decreased activity of BCHE protein CTD PMID:4631366 NCBI chr13:104,946,732...105,007,568 JBrowse link
etoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 affects phosphorylation
multiple interactions		 EXP etoxazole affects the phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]		 CTD PMID:31744678
G ATF6 activating transcription factor 6 increases cleavage EXP etoxazole results in increased cleavage of ATF6 protein CTD PMID:31744678 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases expression EXP etoxazole results in increased expression of BAK1 protein CTD PMID:31744678 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP etoxazole results in increased expression of BAX protein CTD PMID:31744678 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G CCND1 cyclin D1 decreases expression EXP etoxazole results in decreased expression of CCND1 mRNA CTD PMID:31744678 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CCNE1 cyclin E1 decreases expression EXP etoxazole results in decreased expression of CCNE1 mRNA CTD PMID:31744678 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,366 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 increases expression EXP etoxazole results in increased expression of CXCL12 mRNA CTD PMID:31744678 NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752 		JBrowse link
G CYCS cytochrome c, somatic increases expression EXP etoxazole results in increased expression of CYCS protein CTD PMID:31744678 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation EXP etoxazole results in increased phosphorylation of EIF2AK3 protein CTD PMID:31744678 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP etoxazole results in increased phosphorylation of EIF2S1 protein CTD PMID:31744678 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP etoxazole results in increased expression of HSPA5 protein CTD PMID:31744678 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G LEPR leptin receptor decreases expression EXP etoxazole results in decreased expression of LEPR mRNA CTD PMID:31744678 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP etoxazole results in increased phosphorylation of MAPK1 protein
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein]		 CTD PMID:31744678 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein] CTD PMID:31744678 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole results in increased phosphorylation of MAPK8 protein]; [SB 203580 co-treated with etoxazole] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [etoxazole results in increased phosphorylation of MAPK8 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK8 protein] CTD PMID:31744678 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G RPS6 ribosomal protein S6 affects phosphorylation
multiple interactions		 EXP etoxazole affects the phosphorylation of RPS6 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]		 CTD PMID:31744678 NCBI chr 1:203,444,360...203,447,643
Ensembl chr 1:203,444,450...203,451,468 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 affects phosphorylation
multiple interactions		 EXP etoxazole affects the phosphorylation of RPS6KB1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]		 CTD PMID:31744678 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G RXRB retinoid X receptor beta decreases expression EXP etoxazole results in decreased expression of RXRB mRNA CTD PMID:31744678 NCBI chr 7:25,236,005...25,242,842
Ensembl chr 7:25,236,007...25,242,875 		JBrowse link
G TNF tumor necrosis factor increases expression EXP etoxazole results in increased expression of TNF mRNA CTD PMID:31744678 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
ezetimibe term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of HMGCR mRNA] CTD PMID:17130282 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,224...84,402,957 		JBrowse link
G LDLR low density lipoprotein receptor increases expression
multiple interactions		 EXP Ezetimibe results in increased expression of LDLR mRNA
Simvastatin promotes the reaction [Ezetimibe results in increased expression of LDLR mRNA]		 CTD PMID:17130282 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 multiple interactions
increases expression		 EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of NPC1L1 mRNA] CTD PMID:17130282 NCBI chr18:50,726,854...50,757,676
Ensembl chr18:50,726,922...50,757,649 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions EXP [Ezetimibe co-treated with Simvastatin] results in increased expression of SREBF1 mRNA CTD PMID:17130282 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions
increases expression		 EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of SREBF2 mRNA] CTD PMID:17130282 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,490...6,784,671 		JBrowse link
fenofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 affects localization EXP Fenofibrate affects the localization of ABCA1 protein CTD PMID:16530456 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion
decreases expression
multiple interactions		 EXP Fenofibrate results in increased secretion of APOA1 protein
Fenofibrate results in decreased expression of APOA1 mRNA
Fenofibrate inhibits the reaction [APOA1 protein results in increased transport of Cholesterol]; Fenofibrate promotes the reaction [APOA1 protein results in increased transport of Cholesterol]		 CTD PMID:16530456 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G SCARB1 scavenger receptor class B member 1 affects localization EXP Fenofibrate affects the localization of SCARB1 protein CTD PMID:16530456 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP [Fenofibrate co-treated with Zinc] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of TNF protein] CTD PMID:15226458 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
flutamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 affects expression EXP Flutamide affects the expression of GJA1 mRNA CTD PMID:20961722 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156 		JBrowse link
fulvestrant term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA10 homeobox A10 decreases expression
multiple interactions		 EXP Fulvestrant results in decreased expression of HOXA10 mRNA
Fulvestrant inhibits the reaction [Estradiol results in increased expression of HOXA10 mRNA]		 CTD PMID:21705055 NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions EXP Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of NOS3 protein]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of NOS3 protein] CTD PMID:17618301 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Fulvestrant inhibits the reaction [Estradiol results in increased expression of PTGS2 mRNA] CTD PMID:21705055 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
gamma-hexachlorocyclohexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase decreases activity EXP Hexachlorocyclohexane results in decreased activity of CAT protein CTD PMID:16838206 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
gefitinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FES FES proto-oncogene, tyrosine kinase multiple interactions
decreases phosphorylation		 EXP Gefitinib inhibits the reaction [FGF2 protein results in increased phosphorylation of FES protein]; Gefitinib inhibits the reaction [VEGFA protein results in increased phosphorylation of FES protein]
Gefitinib results in decreased phosphorylation of FES protein		 CTD PMID:19885553 NCBI chr 7:53,472,947...53,485,084
Ensembl chr 7:53,472,947...53,485,082 		JBrowse link
G FGF2 fibroblast growth factor 2 multiple interactions EXP Gefitinib inhibits the reaction [FGF2 protein results in increased phosphorylation of FES protein] CTD PMID:19885553 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions EXP Gefitinib inhibits the reaction [VEGFA protein results in increased phosphorylation of FES protein] CTD PMID:19885553 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
glyburide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP Glyburide inhibits the reaction [Carvedilol results in decreased expression of EDN1 protein] CTD PMID:18840580 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP Haloperidol inhibits the reaction [Cocaine results in increased expression of EDN1 protein] CTD PMID:9714087 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
hexachlorobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions EXP Hexachlorobenzene inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol]; Hexachlorobenzene results in decreased expression of and results in decreased secretion of ADIPOQ protein CTD PMID:28284726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ADIPOR1 adiponectin receptor 1 decreases expression EXP Hexachlorobenzene results in decreased expression of ADIPOR1 protein CTD PMID:28284726 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686 		JBrowse link
G ADIPOR2 adiponectin receptor 2 decreases expression EXP Hexachlorobenzene results in decreased expression of ADIPOR2 protein CTD PMID:28284726 NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression EXP Hexachlorobenzene results in increased expression of CYP11A1 protein CTD PMID:21296658 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression EXP Hexachlorobenzene results in decreased expression of CYP17A1 protein CTD PMID:21296658 NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041 		JBrowse link
G CYP19A3 cytochrome P450 19A3 decreases expression EXP Hexachlorobenzene results in decreased expression of CYP19A1 protein CTD PMID:21296658 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 decreases expression EXP Hexachlorobenzene results in decreased expression of HSD17B1 protein CTD PMID:21296658 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548 		JBrowse link
hypochlorous acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 multiple interactions EXP Hypochlorous Acid inhibits the reaction [NOS3 protein binds to NOS3 protein] CTD PMID:17762155 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
indometacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen affects activity EXP Indomethacin affects the activity of AGT protein CTD PMID:21127344 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Indomethacin results in increased expression of DDIT3 mRNA CTD PMID:18799549 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Indomethacin results in increased expression of HSPA5 mRNA CTD PMID:18799549 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
iodomethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 increases alkylation EXP methyl iodide results in increased alkylation of PGK1 protein CTD PMID:6697999 NCBI chr  X:62,187,472...62,210,321
Ensembl chr  X:62,187,434...62,210,705 		JBrowse link
itraconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB4 ATP binding cassette subfamily B member 4 multiple interactions EXP Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] CTD PMID:21056966 NCBI chr 9:93,171,371...93,262,124 JBrowse link
ketoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 multiple interactions EXP Ketoconazole inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Ketoconazole inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone]; Ketoconazole inhibits the reaction [CYP3A29 protein results in increased oxidation of Nifedipine] CTD PMID:20863320 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944 		JBrowse link
lapatinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHB follicle stimulating hormone subunit beta decreases activity
multiple interactions		 EXP Lapatinib results in decreased activity of FSHB protein
Lapatinib inhibits the reaction [FSHB protein results in increased abundance of Progesterone]		 CTD PMID:23375200 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274 		JBrowse link
G LHB luteinizing hormone subunit beta decreases activity
multiple interactions		 EXP Lapatinib results in decreased activity of LHB protein
Lapatinib inhibits the reaction [LHB protein results in increased abundance of Progesterone]		 CTD PMID:23375200 NCBI chr 6:54,263,574...54,269,286 JBrowse link
LY294002 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:16239170 PMID:31744678
G CCL2 chemokine (C-C motif) ligand 2 decreases expression
multiple interactions		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of CCL2 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [titanium dioxide results in increased expression of CCL2 mRNA]		 CTD PMID:23380242 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein CTD PMID:31744678 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein CTD PMID:31744678 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole results in increased phosphorylation of MAPK8 protein] CTD PMID:31744678 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein] CTD PMID:16239170 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G RPS6 ribosomal protein S6 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of RPS6 protein] CTD PMID:31744678 NCBI chr 1:203,444,360...203,447,643
Ensembl chr 1:203,444,450...203,451,468 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein] CTD PMID:31744678 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] CTD PMID:23380242 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
methoctramine tetrahydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions EXP methoctramine inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM2 protein] CTD PMID:8744975 NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186 		JBrowse link
methoxychlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression
multiple interactions		 EXP Methoxychlor results in increased expression of CYP11A1 mRNA
Methoxychlor promotes the reaction [Cholera Toxin results in increased expression of CYP11A1 mRNA]		 CTD PMID:11226075 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
metolachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B multiple interactions EXP CYP2B6B protein results in increased metabolism of and results in decreased susceptibility to metolachlor CTD PMID:16315095 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334 		JBrowse link
ML-7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL9 myosin light chain 9 decreases phosphorylation EXP ML 7 results in decreased phosphorylation of MYL9 protein CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,293 		JBrowse link
G MYLK myosin light chain kinase multiple interactions EXP [ML 7 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium CTD PMID:9506478 NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668 		JBrowse link
monobromobimane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100739508 glutathione S-transferase P-like decreases activity
multiple interactions		 EXP monobromobimane results in decreased activity of GSTP1 protein
GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione]		 CTD PMID:14573868 NCBI chr 2:5,005,498...5,009,247 JBrowse link
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Brimonidine Tartrate results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] CTD PMID:17680988 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728 		JBrowse link
G IL6 interleukin 6 decreases expression
multiple interactions		 EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of IL6 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of IL6 protein]		 CTD PMID:24105867 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
norflurazon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C49 cytochrome P450 2C49 multiple interactions EXP CYP2C49 protein results in increased metabolism of and results in decreased susceptibility to norflurazone CTD PMID:16315095 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
ochratoxin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP ochratoxin A results in decreased phosphorylation of AKT1 protein CTD PMID:30287338
G ANXA5 annexin A5 decreases expression EXP ochratoxin A results in decreased expression of ANXA5 mRNA CTD PMID:14994279 NCBI chr 8:102,387,833...102,420,868
Ensembl chr 8:102,388,103...102,425,750 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of APAF1 mRNA; ochratoxin A results in increased expression of APAF1 protein
fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 protein]		 CTD PMID:36397609 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364 		JBrowse link
G ATG5 autophagy related 5 multiple interactions
increases expression		 EXP ATG5 protein affects the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; ATG5 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein]
ochratoxin A results in increased expression of ATG5 protein		 CTD PMID:28699257 PMID:30287338 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]
ochratoxin A results in increased expression of BAX mRNA; ochratoxin A results in increased expression of BAX protein		 CTD PMID:33905761 PMID:36397609 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
affects expression		 EXP [fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in decreased expression of BCL2 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in decreased expression of BCL2 protein]; ochratoxin A promotes the reaction [fumonisin B1 results in decreased expression of BCL2 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA]; TLR4 protein affects the reaction [ochratoxin A affects the expression of BCL2 mRNA]
ochratoxin A results in decreased expression of BCL2 mRNA; ochratoxin A results in decreased expression of BCL2 protein		 CTD PMID:28528741 PMID:29080797 PMID:33905761 PMID:36397609 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BECN1 beclin 1 multiple interactions
increases expression		 EXP BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein]
ochratoxin A results in increased expression of BECN1 protein		 CTD PMID:30287338 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G BRCA1 BRCA1 DNA repair associated increases expression EXP ochratoxin A results in increased expression of BRCA1 protein CTD PMID:32454083 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of and results in increased cleavage of CASP1 protein]; ochratoxin A results in increased expression of and results in increased cleavage of CASP1 protein; Taurine inhibits the reaction [ochratoxin A results in increased expression of and results in increased cleavage of CASP1 protein] CTD PMID:36281498 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases cleavage		 EXP 3-methyladenine promotes the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein]; ATG5 protein affects the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 protein modified form]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP3 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP3 protein modified form]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP3 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein]
ochratoxin A results in increased expression of CASP3 mRNA; ochratoxin A results in increased expression of CASP3 protein; ochratoxin A results in increased expression of CASP3 protein modified form		 CTD PMID:30287338 PMID:33905761 PMID:36397609 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression		 EXP [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein modified form]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein modified form]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]
ochratoxin A results in increased expression of CASP9 mRNA; ochratoxin A results in increased expression of CASP9 protein; ochratoxin A results in increased expression of CASP9 protein modified form		 CTD PMID:33905761 PMID:36397609 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007 		JBrowse link
G CAT catalase decreases expression
multiple interactions		 EXP ochratoxin A results in decreased expression of CAT mRNA; ochratoxin A results in decreased expression of CAT protein
Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of CAT mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of CAT mRNA]		 CTD PMID:18547704 PMID:36281498 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CRYAB crystallin alpha B increases expression EXP ochratoxin A results in increased expression of CRYAB mRNA CTD PMID:14994279 NCBI chr 9:39,638,505...39,643,530
Ensembl chr 9:39,638,506...39,643,530 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions
increases expression		 EXP fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CYCS mRNA] CTD PMID:36397609 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G CYP2G2 cytochrome P450 family 2 subfamily G member 2 decreases expression EXP ochratoxin A results in decreased expression of CYP2A6 mRNA CTD PMID:14994279 NCBI chr 6:49,069,613...49,084,953 JBrowse link
G DAD1 defender against cell death 1 decreases expression EXP ochratoxin A results in decreased expression of DAD1 mRNA CTD PMID:14994279 NCBI chr 7:76,432,040...76,457,403
Ensembl chr 7:76,432,051...76,457,192 		JBrowse link
G DNMT1 DNA methyltransferase 1 increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of DNMT1 mRNA; ochratoxin A results in increased expression of DNMT1 protein
Decitabine inhibits the reaction [ochratoxin A results in increased expression of DNMT1 mRNA]; Decitabine inhibits the reaction [ochratoxin A results in increased expression of DNMT1 protein]		 CTD PMID:29080797 PMID:30923867 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha increases expression EXP ochratoxin A results in increased expression of DNMT3A mRNA CTD PMID:29080797 PMID:30923867 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases expression
multiple interactions		 EXP ochratoxin A results in decreased expression of GCLC mRNA
ochratoxin A inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]		 CTD PMID:18547363 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530 		JBrowse link
G GLMN glomulin, FKBP associated protein increases expression EXP ochratoxin A results in increased expression of GLMN mRNA CTD PMID:14994279 NCBI chr 4:124,773,957...124,813,336
Ensembl chr 4:124,773,980...124,813,335 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression
multiple interactions		 EXP ochratoxin A results in decreased expression of GPX1 mRNA
Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA]		 CTD PMID:36281498 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G GPX4 glutathione peroxidase 4 decreases expression
multiple interactions		 EXP ochratoxin A results in decreased expression of GPX4 mRNA
Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA]		 CTD PMID:36281498 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931 		JBrowse link
G GSDMD gasdermin D multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein]; Taurine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein] CTD PMID:36281498 NCBI chr 4:995,753...1,001,964
Ensembl chr 4:995,763...1,000,271 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions
decreases expression		 EXP ochratoxin A inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA]
ochratoxin A results in decreased expression of GSTA1 mRNA		 CTD PMID:18547363 NCBI chr 7:46,538,743...46,550,781
Ensembl chr 7:46,538,032...46,548,670 		JBrowse link
G H2AX H2A.X variant histone multiple interactions
increases expression		 EXP alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [ochratoxin A results in increased expression of H2AX protein]; Decitabine inhibits the reaction [ochratoxin A results in increased expression of H2AX protein]; STAT3 protein affects the reaction [ochratoxin A results in increased expression of H2AX protein] CTD PMID:30923867 PMID:32454083 NCBI chr 9:46,308,824...46,310,494
Ensembl chr 9:46,309,653...46,310,084 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 multiple interactions EXP [fumonisin B1 co-treated with ochratoxin A] results in increased expression of HAVCR1 mRNA CTD PMID:33905761 NCBI chr16:66,162,318...66,208,868 JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions
increases expression		 EXP Panobinostat inhibits the reaction [ochratoxin A results in increased expression of HDAC1 mRNA]; Panobinostat inhibits the reaction [ochratoxin A results in increased expression of HDAC1 protein]
ochratoxin A results in increased expression of HDAC1 mRNA; ochratoxin A results in increased expression of HDAC1 protein		 CTD PMID:29080797 NCBI chr 6:88,749,611...88,785,220
Ensembl chr 6:88,749,634...88,785,411 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression
decreases expression		 EXP ochratoxin A results in increased expression of HSP90B1 mRNA
ochratoxin A results in decreased expression of HSP90B1 mRNA		 CTD PMID:14994279 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP ochratoxin A results in increased expression of HSPA5 mRNA; ochratoxin A results in increased expression of HSPA5 protein CTD PMID:28699257 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression EXP ochratoxin A results in decreased expression of HSPD1 mRNA CTD PMID:14994279 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G ID2 inhibitor of DNA binding 2 decreases expression EXP ochratoxin A results in decreased expression of ID2 mRNA CTD PMID:14994279 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 increases expression EXP ochratoxin A results in increased expression of IGFBP2 mRNA CTD PMID:14994279 NCBI chr15:118,822,092...118,850,985
Ensembl chr15:118,822,047...118,850,976 		JBrowse link
G IL18 interleukin 18 increases expression EXP ochratoxin A results in increased expression of IL18 protein CTD PMID:36281498 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]; TLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]] CTD PMID:28528741 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL2 interleukin 2 decreases secretion EXP ochratoxin A results in decreased secretion of IL2 protein CTD PMID:28699257 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4 interleukin 4 increases expression EXP ochratoxin A results in increased expression of IL4 mRNA CTD PMID:14994279 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of IL6 mRNA
NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of IL6 mRNA]		 CTD PMID:28710020 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions
increases phosphorylation		 EXP Decitabine inhibits the reaction [ochratoxin A results in increased phosphorylation of JAK2 protein] CTD PMID:30923867 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G LCN2 lipocalin 2 multiple interactions EXP [fumonisin B1 co-treated with ochratoxin A] results in increased expression of LCN2 mRNA CTD PMID:33905761 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644 		JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of IL1B protein]; Taurine inhibits the reaction [ochratoxin A results in increased expression of IL1B protein] CTD PMID:36281498
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP ochratoxin A results in increased phosphorylation of MAPK1 protein
ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]		 CTD PMID:28528741 PMID:28699257 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
ochratoxin A results in increased phosphorylation of MAPK3 protein		 CTD PMID:28528741 PMID:28699257 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases phosphorylation EXP ochratoxin A results in decreased phosphorylation of MTOR protein CTD PMID:30287338 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions EXP ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]; ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] CTD PMID:28528741 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G NEIL1 nei like DNA glycosylase 1 decreases expression
multiple interactions		 EXP ochratoxin A results in decreased expression of NEIL1 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]; Decitabine inhibits the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]		 CTD PMID:30923867 NCBI chr 7:58,261,761...58,269,001
Ensembl chr 7:58,261,769...58,268,522 		JBrowse link
G NEIL3 nei like DNA glycosylase 3 multiple interactions
decreases expression		 EXP alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [ochratoxin A results in decreased expression of NEIL3 mRNA]; Decitabine inhibits the reaction [ochratoxin A results in decreased expression of NEIL3 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL3 mRNA] CTD PMID:30923867 NCBI chr15:39,416,073...39,632,313
Ensembl chr15:39,581,856...39,632,308 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases activity
multiple interactions
decreases expression		 EXP ochratoxin A results in decreased activity of NFE2L2 protein
NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 mRNA]; NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of TP53 protein]; ochratoxin A inhibits the reaction [sulforaphane affects the localization of NFE2L2 protein]; ochratoxin A inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]; ochratoxin A inhibits the reaction [sulforaphane results in increased expression of NFE2L2 mRNA]
ochratoxin A results in decreased expression of NFE2L2 mRNA		 CTD PMID:18547363 PMID:18547704 PMID:28710020 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of NLRP3 protein]; Taurine inhibits the reaction [ochratoxin A results in increased expression of NLRP3 protein] CTD PMID:36281498 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of INOS mRNA
Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of INOS mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of INOS mRNA]		 CTD PMID:36281498 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NPM1 nucleophosmin 1 increases expression EXP ochratoxin A results in increased expression of NPM1 mRNA CTD PMID:14994279 NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,298...52,781,771 		JBrowse link
G NTN1 netrin 1 multiple interactions
increases expression		 EXP fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of NTN1 mRNA] CTD PMID:33905761 NCBI chr12:54,089,444...54,292,191
Ensembl chr12:54,089,472...54,292,193 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase decreases expression
multiple interactions		 EXP ochratoxin A results in decreased expression of OGG1 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [ochratoxin A results in decreased expression of OGG1 mRNA]; Decitabine inhibits the reaction [ochratoxin A results in decreased expression of OGG1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of OGG1 mRNA]		 CTD PMID:30923867 NCBI chr13:66,038,669...66,045,478 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases expression		 EXP ochratoxin A results in increased cleavage of PARP1 protein
3-methyladenine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein]; ATG5 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein]; BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein]; Chloroquine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein]
ochratoxin A results in increased expression of PARP1 protein		 CTD PMID:30287338 PMID:32454083 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP ochratoxin A results in decreased expression of PCK1 mRNA; ochratoxin A results in decreased expression of PCK1 protein CTD PMID:3753873 NCBI chr17:57,930,507...57,936,523
Ensembl chr17:57,930,432...57,936,522 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression EXP ochratoxin A results in decreased expression of PCNA protein CTD PMID:32454083 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744 		JBrowse link
G PPIA peptidylprolyl isomerase A increases expression EXP ochratoxin A results in increased expression of PPIA mRNA CTD PMID:14994279 NCBI chr18:50,563,130...50,566,857 JBrowse link
G PRDX1 peroxiredoxin 1 decreases expression EXP ochratoxin A results in decreased expression of PRDX1 mRNA CTD PMID:14994279 NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,395...165,861,442 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of PTGS2 mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of PTGS2 mRNA] CTD PMID:36281498 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PTMA prothymosin alpha decreases expression EXP ochratoxin A results in decreased expression of PTMA mRNA CTD PMID:14994279 NCBI chr15:132,353,763...132,361,442
Ensembl chr15:132,355,655...132,361,435 		JBrowse link
G PYCARD PYD and CARD domain containing increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of PYCARD protein
Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of PYCARD protein]; Taurine inhibits the reaction [ochratoxin A results in increased expression of PYCARD protein]		 CTD PMID:36281498 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786 		JBrowse link
G RAD51 RAD51 recombinase increases expression EXP ochratoxin A results in increased expression of RAD51 protein CTD PMID:32454083 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,665...130,640,136 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:28528741 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RPA2 replication protein A2 increases expression EXP ochratoxin A results in increased expression of RPA2 protein CTD PMID:32454083 NCBI chr 6:85,032,604...85,045,899
Ensembl chr 6:85,031,582...85,045,915 		JBrowse link
G RPS5 ribosomal protein S5 increases expression EXP ochratoxin A results in increased expression of RPS5 mRNA CTD PMID:14994279 NCBI chr 6:62,967,955...62,974,353
Ensembl chr 6:62,967,994...62,974,350 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of SOCS3 mRNA; ochratoxin A results in increased expression of SOCS3 protein
Decitabine promotes the reaction [ochratoxin A results in increased expression of SOCS3 mRNA]; Decitabine promotes the reaction [ochratoxin A results in increased expression of SOCS3 protein]		 CTD PMID:30923867 NCBI chr12:3,643,832...3,647,015
Ensembl chr12:3,643,929...3,647,009 		JBrowse link
G SOD1 superoxide dismutase 1 decreases activity EXP ochratoxin A results in decreased activity of SOD1 protein CTD PMID:18547704 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions
increases expression		 EXP fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of SPP1 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of SPP1 mRNA] CTD PMID:33905761 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
decreases expression		 EXP Chloroquine inhibits the reaction [ochratoxin A results in decreased expression of SQSTM1 protein] CTD PMID:30287338 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions
increases phosphorylation		 EXP Decitabine inhibits the reaction [ochratoxin A results in increased phosphorylation of STAT3 protein]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL3 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of OGG1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in increased expression of H2AX protein] CTD PMID:30923867 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 decreases expression EXP ochratoxin A results in decreased expression of SUMO1 mRNA CTD PMID:14994279 NCBI chr15:105,820,237...105,850,099
Ensembl chr15:105,818,858...105,850,233 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression
multiple interactions		 EXP ochratoxin A results in increased expression of TGFB1 mRNA
NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 mRNA]; sulforaphane inhibits the reaction [ochratoxin A results in increased expression of TGFB1 mRNA]		 CTD PMID:28710020 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 increases expression EXP ochratoxin A results in increased expression of TIMP2 mRNA CTD PMID:14994279 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834 		JBrowse link
G TJP1 tight junction protein 1 affects localization EXP ochratoxin A affects the localization of TJP1 protein CTD PMID:14994279 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836 		JBrowse link
G TLR4 toll like receptor 4 multiple interactions EXP ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]; ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]; TLR4 protein affects the reaction [ochratoxin A affects the expression of BCL2 mRNA]; TLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]; TLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] CTD PMID:28528741 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases secretion		 EXP ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; TLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]
ochratoxin A results in increased secretion of TNF protein		 CTD PMID:28528741 PMID:28699257 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression		 EXP NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of TP53 protein] CTD PMID:28710020 PMID:32454083 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G XPA XPA, DNA damage recognition and repair factor decreases expression EXP ochratoxin A results in decreased expression of XPA mRNA CTD PMID:14994279 NCBI chr 1:239,532,331...239,568,589
Ensembl chr 1:239,532,272...239,568,570 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 increases expression EXP ochratoxin A results in increased expression of XRCC1 protein CTD PMID:32454083 NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,689...50,425,729 		JBrowse link
pentachlorobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression EXP pentachlorobenzene results in increased expression of CYP11A1 protein CTD PMID:21296658 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 increases expression EXP pentachlorobenzene results in increased expression of CYP17A1 protein CTD PMID:21296658 NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041 		JBrowse link
G CYP19A3 cytochrome P450 19A3 increases expression EXP pentachlorobenzene results in increased expression of CYP19A1 protein CTD PMID:21296658 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
salubrinal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation EXP salubrinal results in increased phosphorylation of EIF2A protein CTD PMID:17464326 NCBI chr13:90,761,453...90,804,274
Ensembl chr13:90,761,465...90,804,274 		JBrowse link
sarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase decreases activity
multiple interactions		 EXP Sarin results in decreased activity of ACHE protein
asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]		 CTD PMID:16021679 PMID:19428926 PMID:20156534 PMID:20888357 PMID:22230262 More... NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605 		JBrowse link
SB 203580 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP SB 203580 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein] CTD PMID:31744678
G CCL2 chemokine (C-C motif) ligand 2 multiple interactions EXP SB 203580 inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [titanium dioxide results in increased expression of CCL2 mRNA] CTD PMID:19265715 PMID:23380242 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein] CTD PMID:31744678 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein] CTD PMID:31744678 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP [SB 203580 co-treated with etoxazole] results in increased phosphorylation of MAPK8 protein CTD PMID:31744678 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G RPS6 ribosomal protein S6 multiple interactions EXP SB 203580 affects the reaction [etoxazole affects the phosphorylation of RPS6 protein] CTD PMID:31744678 NCBI chr 1:203,444,360...203,447,643
Ensembl chr 1:203,444,450...203,451,468 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions EXP SB 203580 affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein] CTD PMID:31744678 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of STAT1 protein] CTD PMID:21783819 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of STAT3 protein] CTD PMID:21783819 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP SB 203580 inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] CTD PMID:23380242 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
sodium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FFAR1 free fatty acid receptor 1 multiple interactions EXP Dietary Fats affects the reaction [Sodium Chloride affects the expression of FFAR1 mRNA]; Sodium Chloride affects the reaction [Dietary Fats affects the expression of FFAR1 mRNA] CTD PMID:31360149 NCBI chr 6:44,837,764...44,841,518 JBrowse link
sodium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A5 solute carrier family 5 member 5 multiple interactions
increases uptake		 EXP sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]
SLC5A5 protein alternative form results in increased uptake of Sodium Iodide; SLC5A5 protein results in increased uptake of Sodium Iodide		 CTD PMID:12586784 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
sodium perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A5 solute carrier family 5 member 5 multiple interactions EXP sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] CTD PMID:12586784 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
G TPO thyroid peroxidase decreases activity EXP sodium perchlorate results in decreased activity of TPO protein CTD PMID:23959146 NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208 		JBrowse link
sulindac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G1B phospholipase A2 group IB multiple interactions EXP Sulindac promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] CTD PMID:10706128 NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,520...40,322,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Sulindac promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] CTD PMID:10706128 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
U50488 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions EXP 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [AGT protein results in increased secretion of Aldosterone] CTD PMID:22100847 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G OPRK1 opioid receptor kappa 1 multiple interactions EXP 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [OPRK1 protein results in increased transport of Barium] CTD PMID:12031848 NCBI chr 4:77,399,298...77,429,025
Ensembl chr 4:77,399,183...77,426,879 		JBrowse link
zinc dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PSP-I porcine seminal protein I multiple interactions
affects folding		 EXP zinc chloride promotes the reaction [PSP-I protein binds to Heparin]
zinc chloride affects the folding of PSP-I protein		 CTD PMID:16819821 NCBI chr14:132,302,376...132,309,388
Ensembl chr14:132,302,352...132,308,106 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5018
    chemical entity 5018
      molecular entity 5017
        main group molecular entity 4975
          p-block molecular entity 4973
            halogen molecular entity 308
              astatine molecular entity + 0
              bromine molecular entity + 34
              chlorine molecular entity + 261
              fluorine molecular entity + 66
              halide + 306
              halogen oxide + 0
              halogen oxoacid + 1
              halogen oxoanion + 2
              halohalide + 0
              interhalogen compound + 0
              iodine molecular entity + 3
              tennessine molecular entity 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5018
    subatomic particle 5009
      composite particle 5009
        hadron 5009
          baryon 5009
            nucleon 5009
              atomic nucleus 5009
                atom 5009
                  main group element atom 4976
                    p-block element atom 4973
                      p-block molecular entity 4973
                        halogen molecular entity 308
                          astatine molecular entity + 0
                          bromine molecular entity + 34
                          chlorine molecular entity + 261
                          fluorine molecular entity + 66
                          halide + 306
                          halogen oxide + 0
                          halogen oxoacid + 1
                          halogen oxoanion + 2
                          halohalide + 0
                          interhalogen compound + 0
                          iodine molecular entity + 3
                          tennessine molecular entity 0
paths to the root