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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:haloalkane
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Accession:CHEBI:24469 term browser browse the term
Definition:A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom.
Synonyms:related_synonym: alkyl halide;   alkyl halides;   haloalkanes


show annotations for term's descendants           Sort by:
flutamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 affects expression EXP Flutamide affects the expression of GJA1 mRNA CTD PMID:20961722 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156 		JBrowse link
iodomethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 increases alkylation EXP methyl iodide results in increased alkylation of PGK1 protein CTD PMID:6697999 NCBI chr  X:62,187,472...62,210,321
Ensembl chr  X:62,187,434...62,210,705 		JBrowse link
norflurazon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP norflurazone results in decreased phosphorylation of AKT1 protein CTD PMID:38432436
G AKT2 AKT serine/threonine kinase 2 decreases phosphorylation EXP norflurazone results in decreased phosphorylation of AKT2 protein CTD PMID:38432436 NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 decreases phosphorylation EXP norflurazone results in decreased phosphorylation of AKT3 protein CTD PMID:38432436 NCBI chr10:16,441,465...16,741,745
Ensembl chr10:16,441,447...16,741,337 		JBrowse link
G ATG5 autophagy related 5 increases expression EXP norflurazone results in increased expression of ATG5 protein CTD PMID:38432436 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha decreases expression EXP norflurazone results in decreased expression of ATP5F1A mRNA CTD PMID:38432436 NCBI chr 1:95,738,789...95,750,835
Ensembl chr 1:95,733,090...95,750,841 		JBrowse link
G ATP5MC1 ATP synthase membrane subunit c locus 1 decreases expression EXP norflurazone results in decreased expression of ATP5MC1 mRNA CTD PMID:38432436 NCBI chr12:25,110,540...25,113,481
Ensembl chr12:25,110,528...25,113,478 		JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 decreases expression EXP norflurazone results in decreased expression of ATP5MC2 mRNA CTD PMID:38432436 NCBI chr 5:18,871,025...18,879,933
Ensembl chr 5:18,871,026...18,879,609 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b decreases expression EXP norflurazone results in decreased expression of ATP5PB mRNA CTD PMID:38432436 NCBI chr 4:108,896,063...108,907,626
Ensembl chr 4:108,896,057...108,907,805 		JBrowse link
G BECN1 beclin 1 increases expression EXP norflurazone results in increased expression of BECN1 protein CTD PMID:38432436 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G CYP2C49 cytochrome P450 2C49 multiple interactions EXP CYP2C49 protein results in increased metabolism of and results in decreased susceptibility to norflurazone CTD PMID:16315095 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation EXP norflurazone results in increased phosphorylation of EIF2A protein CTD PMID:38432436 NCBI chr13:90,761,453...90,804,274
Ensembl chr13:90,761,465...90,804,274 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP norflurazone results in increased expression of and results in increased phosphorylation of HSPA5 protein CTD PMID:38432436 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 increases expression EXP norflurazone results in increased expression of ITPR1 protein CTD PMID:38432436 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation EXP norflurazone results in decreased phosphorylation of MAPK1 protein CTD PMID:38432436 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 increases phosphorylation EXP norflurazone results in increased phosphorylation of MAPK14 protein CTD PMID:38432436 NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,877...31,862,031 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation EXP norflurazone results in decreased phosphorylation of MAPK3 protein CTD PMID:38432436 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression EXP norflurazone results in decreased expression of ATP6 mRNA CTD PMID:38432436 NCBI chr MT:9,120...9,800
Ensembl chr MT:9,120...9,800 		JBrowse link
G NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression EXP norflurazone results in decreased expression of NDUFS2 mRNA CTD PMID:38432436 NCBI chr 4:89,246,958...89,257,090
Ensembl chr 4:89,246,960...89,257,085 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression EXP norflurazone results in decreased expression of NDUFS3 mRNA CTD PMID:38432436 NCBI chr 2:15,031,147...15,036,880
Ensembl chr 2:15,031,149...15,036,880 		JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 decreases expression EXP norflurazone results in decreased expression of NDUFV1 mRNA CTD PMID:38432436 NCBI chr 2:4,958,508...4,964,211
Ensembl chr 2:4,958,522...4,964,216 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases phosphorylation EXP norflurazone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:38432436 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G SMAD2 SMAD family member 2 decreases expression EXP norflurazone results in decreased expression of SMAD2 mRNA CTD PMID:38432436 NCBI chr 1:97,415,360...97,511,388
Ensembl chr 1:97,415,716...97,511,357 		JBrowse link
G SMAD4 SMAD family member 4 decreases expression EXP norflurazone results in decreased expression of SMAD4 mRNA CTD PMID:38432436 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SPP1 secreted phosphoprotein 1 decreases expression EXP norflurazone results in decreased expression of SPP1 mRNA CTD PMID:38432436 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G SQSTM1 sequestosome 1 increases phosphorylation EXP norflurazone results in increased phosphorylation of SQSTM1 protein CTD PMID:38432436 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938 		JBrowse link
G UQCRB ubiquinol-cytochrome c reductase binding protein decreases expression EXP norflurazone results in decreased expression of UQCRB mRNA CTD PMID:38432436 NCBI chr 4:40,403,272...40,409,080
Ensembl chr 4:40,403,109...40,409,057 		JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 decreases expression EXP norflurazone results in decreased expression of UQCRC2 mRNA CTD PMID:38432436 NCBI chr 3:24,197,743...24,228,831
Ensembl chr 3:24,197,747...24,228,832 		JBrowse link
G UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII decreases expression EXP norflurazone results in decreased expression of UQCRQ mRNA CTD PMID:38432436 NCBI chr 2:135,186,366...135,188,237
Ensembl chr 2:135,186,501...135,188,293 		JBrowse link
G VDAC1 voltage dependent anion channel 1 increases expression EXP norflurazone results in increased expression of VDAC1 protein CTD PMID:38432436 NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,191...136,396,301 		JBrowse link
perfluorooctanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP perfluorooctanoic acid results in decreased phosphorylation of AKT1 protein CTD PMID:38145882
G ALB albumin affects binding EXP perfluorooctanoic acid binds to ALB protein CTD PMID:38518100 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5178
    chemical entity 5178
      group 5157
        polyatomic entity 5157
          heteroatomic molecular entity 5127
            halide 339
              organohalogen compound 330
                halohydrocarbon 49
                  haloalkane 32
                    1,1,2-Trichlorotrifluoroethane 0
                    1,8-dichloro-perfluorooctane 0
                    1-bromo-2-chloroethane 0
                    1-haloalkane 0
                    bromoalkane + 0
                    chloroalkane + 0
                    fluoroalkane + 31
                    halomethane + 31
                    halothane + 0
                    iodoalkane + 1
                    perflubron 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5178
    subatomic particle 5169
      composite particle 5169
        hadron 5169
          baryon 5169
            nucleon 5169
              atomic nucleus 5169
                atom 5169
                  main group element atom 5141
                    main group molecular entity 5140
                      s-block molecular entity 5072
                        hydrogen molecular entity 5066
                          hydrides 4684
                            organic hydride 4538
                              organic fundamental parent 4538
                                hydrocarbon 4501
                                  halohydrocarbon 49
                                    haloalkane 32
                                      1,1,2-Trichlorotrifluoroethane 0
                                      1,8-dichloro-perfluorooctane 0
                                      1-bromo-2-chloroethane 0
                                      1-haloalkane 0
                                      bromoalkane + 0
                                      chloroalkane + 0
                                      fluoroalkane + 31
                                      halomethane + 31
                                      halothane + 0
                                      iodoalkane + 1
                                      perflubron 0
paths to the root