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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycolaldehydes
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Accession:CHEBI:24387 term browser browse the term
Definition:An aldehyde derived from a glycol by reduction of one of the hydroxy groups.



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glycolaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases degradation
ISO glycolaldehyde inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]
glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein]
glycolaldehyde results in increased degradation of ABCA1 protein
CTD PMID:15983222 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde CTD PMID:21376711 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein] CTD PMID:15983222 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Cat catalase decreases response to substance
decreases activity
EXP CAT protein results in decreased susceptibility to glycolaldehyde
glycolaldehyde results in decreased activity of CAT protein
CTD PMID:21376711 PMID:21378371 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ctss cathepsin S decreases activity ISO glycolaldehyde results in decreased activity of CTSS protein CTD PMID:16671891 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Glo1 glyoxalase 1 decreases activity EXP glycolaldehyde results in decreased activity of GLO1 protein CTD PMID:21378371 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        solvent 17050
          formic acid 9050
            formyl group 9012
              aldehyde 9012
                hydroxyaldehyde 805
                  glycolaldehydes 6
                    3-indoleglycolaldehyde 0
                    3-methoxy-4-hydroxyphenylglycolaldehyde 0
                    glycolaldehyde + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        carboacyl group 17727
                                          univalent carboacyl group 17727
                                            formyl group 9012
                                              aldehyde 9012
                                                hydroxyaldehyde 805
                                                  glycolaldehydes 6
                                                    3-indoleglycolaldehyde 0
                                                    3-methoxy-4-hydroxyphenylglycolaldehyde 0
                                                    glycolaldehyde + 6
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