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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glutathione conjugate
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Accession:CHEBI:24335 term browser browse the term
Definition:Any bioconjugate in which glutathione is one of the components



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8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta3 glutathione S-transferase alpha 3 affects binding ISO 8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 binds to GSTA3 protein CTD PMID:8910329 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
S-(2,4-dinitrophenyl)glutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects export
affects transport
increases export
multiple interactions
ISO ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione
ABCC1 protein affects the transport of S-(2,4-dinitrophenyl)glutathione
ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione
flavone inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione]; hesperetin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]; Mefloquine inhibits the reaction [ABCC1 protein affects the transport of S-(2,4-dinitrophenyl)glutathione]; naringenin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]; Quercetin inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione]; Quercetin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]; resveratrol inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]; Silymarin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]; taxifolin inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione]; verlukast inhibits the reaction [ABCC1 protein affects the transport of S-(2,4-dinitrophenyl)glutathione]
CTD PMID:15041478 PMID:16004972 PMID:16156793 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases transport
affects transport
increases export
EXP
ISO
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Spironolactone results in increased expression of ABCC2 protein] which results in increased transport of S-(2,4-dinitrophenyl)glutathione; [sulfanitran results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; Acetaminophen promotes the reaction [ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione]; S-(2,4-dinitrophenyl)glutathione inhibits the reaction [ABCC2 protein results in increased transport of temocaprilat]; temocaprilat inhibits the reaction [ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione]; Ursodeoxycholic Acid promotes the reaction [ABCC2 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]
ABCC2 protein affects the transport of S-(2,4-dinitrophenyl)glutathione
CTD PMID:9067317 PMID:9430713 PMID:9525973 PMID:15276087 PMID:15652244 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO S-(2,4-dinitrophenyl)glutathione inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate] CTD PMID:11856762 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      chemical role 19320
        antioxidant 14438
          glutathione 375
            glutathione derivative 59
              glutathione conjugate 4
                (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid 0
                (8S)-glutathionyl-(7R,17S)-dihydroxy-(4Z,9,11,13Z,15E,19Z)-docosahexaenoic acid 0
                (E)-1-(glutathion-S-yl)-2-(indol-3-yl)acetohydroximate 0
                (R)-PGA2-S-glutathione conjugate 0
                (R)-PGJ2-S-glutathione conjugate 0
                (S)-PGA2-S-glutathione conjugate 0
                (S)-PGJ2-S-glutathione conjugate 0
                (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate 0
                11(S),15(S)-dihydroxy-14(R)-(S-glutathionyl)-5(Z),8(Z),12(E)-icosatrienoic acid 0
                16(S)-glutathionyl-17(R)-hydroxy-(4Z,7Z,10,12,14,19Z)-docosahexaenoic acid 0
                1beta-glutathionylseleno-N-acetyl-D-galactosamine 0
                2-(glutathion-S-yl)-1,4-hydroquinone 0
                8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 1
                S-(1,4-dihydroxy-3-methylnaphthalen-2-yl)glutathione 0
                S-(2,4-dinitrophenyl)glutathione 3
                S-(4-oxobutan-2-yl)glutathione 0
                S-[(2-phenylethyl)carbamothioyl]glutathione 0
                gammaGluCys(IAN)Gly 0
                neocarzinostatin-glutathione chromophore 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        carboacyl group 17469
                                          univalent carboacyl group 17469
                                            carbamoyl group 17285
                                              carboxamide 17285
                                                peptide 9455
                                                  oligopeptide 1268
                                                    tripeptide 929
                                                      glutathione 375
                                                        glutathione derivative 59
                                                          glutathione conjugate 4
                                                            (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid 0
                                                            (8S)-glutathionyl-(7R,17S)-dihydroxy-(4Z,9,11,13Z,15E,19Z)-docosahexaenoic acid 0
                                                            (E)-1-(glutathion-S-yl)-2-(indol-3-yl)acetohydroximate 0
                                                            (R)-PGA2-S-glutathione conjugate 0
                                                            (R)-PGJ2-S-glutathione conjugate 0
                                                            (S)-PGA2-S-glutathione conjugate 0
                                                            (S)-PGJ2-S-glutathione conjugate 0
                                                            (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate 0
                                                            11(S),15(S)-dihydroxy-14(R)-(S-glutathionyl)-5(Z),8(Z),12(E)-icosatrienoic acid 0
                                                            16(S)-glutathionyl-17(R)-hydroxy-(4Z,7Z,10,12,14,19Z)-docosahexaenoic acid 0
                                                            1beta-glutathionylseleno-N-acetyl-D-galactosamine 0
                                                            2-(glutathion-S-yl)-1,4-hydroquinone 0
                                                            8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 1
                                                            S-(1,4-dihydroxy-3-methylnaphthalen-2-yl)glutathione 0
                                                            S-(2,4-dinitrophenyl)glutathione 3
                                                            S-(4-oxobutan-2-yl)glutathione 0
                                                            S-[(2-phenylethyl)carbamothioyl]glutathione 0
                                                            gammaGluCys(IAN)Gly 0
                                                            neocarzinostatin-glutathione chromophore 0
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