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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glucoside
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Accession:CHEBI:24278 term browser browse the term
Synonyms:related_synonym: glucosides



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(+)-syringaresinol beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] CTD PMID:31077737 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions EXP [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein CTD PMID:31077737 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Cat catalase multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:31077737 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] CTD PMID:31077737 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Il10 interleukin 10 multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:31077737 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] CTD PMID:31077737 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] CTD PMID:31077737 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:31077737 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions EXP [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein CTD PMID:31077737 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] CTD PMID:31077737 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] CTD PMID:31077737 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
(20S)-ginsenoside Rh1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos FBJ osteosarcoma oncogene increases expression ISO ginsenoside Rh1 results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21875580 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] CTD PMID:16557482 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 decreases expression EXP ginsenoside Rh1 results in decreased expression of IL4 CTD PMID:22855946 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Itga4 integrin alpha 4 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 2:79,084,767...79,163,458
Ensembl chr 2:79,085,770...79,163,467
JBrowse link
G Itgal integrin alpha L multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Itgb2 integrin beta 2 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Jun jun proto-oncogene decreases activity EXP ginsenoside Rh1 results in decreased activity of JUN protein CTD PMID:22855946 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Lpl lipoprotein lipase increases secretion EXP ginsenoside Rh1 results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Pgr progesterone receptor increases expression ISO ginsenoside Rh1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP ginsenoside Rh1 inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]; ginsenoside Rh1 inhibits the reaction [bisphenol A results in increased expression of PPARG protein] CTD PMID:32623698 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] CTD PMID:16557482 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:21875580 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO ginsenoside Rh1 results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
JBrowse link
G Tnf tumor necrosis factor decreases response to substance
multiple interactions
decreases expression
ISO
EXP
ginsenoside Rh1 results in decreased susceptibility to TNF protein
ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
ginsenoside Rh1 results in decreased expression of TNF
CTD PMID:16557482 PMID:21875580 PMID:22855946 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:21875580 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
(20S)-ginsenoside Rh2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation ISO ginsenoside Rh2 results in decreased phosphorylation of AKT1 protein CTD PMID:32762018 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Bax BCL2-associated X protein increases expression ISO ginsenoside Rh2 results in increased expression of BAX protein CTD PMID:26482938 PMID:32762018 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO ginsenoside Rh2 results in decreased expression of BCL2 protein CTD PMID:26482938 PMID:32762018 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 increases cleavage
decreases expression
ISO ginsenoside Rh2 results in increased cleavage of CASP3 protein
ginsenoside Rh2 results in decreased expression of CASP3 protein
CTD PMID:26482938 PMID:32762018 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 decreases expression ISO ginsenoside Rh2 results in decreased expression of CASP9 protein CTD PMID:32762018 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO ginsenoside Rh2 results in decreased expression of CCND1 protein CTD PMID:26482938 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC1 protein CTD PMID:26482938 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC2 protein CTD PMID:26482938 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Hdac6 histone deacetylase 6 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC6 protein CTD PMID:26482938 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rh2 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation
increases phosphorylation
ISO ginsenoside Rh2 results in decreased phosphorylation of MAPK1 protein
ginsenoside Rh2 results in increased phosphorylation of MAPK1 protein
CTD PMID:26482938 PMID:32762018 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation
increases phosphorylation
ISO ginsenoside Rh2 results in decreased phosphorylation of MAPK3 protein
ginsenoside Rh2 results in increased phosphorylation of MAPK3 protein
CTD PMID:26482938 PMID:32762018 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO ginsenoside Rh2 results in decreased phosphorylation of MTOR protein CTD PMID:32762018 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases expression ISO ginsenoside Rh2 results in increased expression of NFKBIA protein CTD PMID:32762018 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO ginsenoside Rh2 results in increased expression of and results in decreased phosphorylation of RELA protein CTD PMID:32762018 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
(R)-amygdalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP
ISO
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:36457260 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP
ISO
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein] CTD PMID:36457260 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Hpse heparanase multiple interactions EXP
ISO
Amygdalin inhibits the reaction [Ovalbumin results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein] CTD PMID:36457260 NCBI chr 5:100,827,350...100,867,582
Ensembl chr 5:100,827,350...100,867,582
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA] CTD PMID:33149750 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:33149750 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO
EXP
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased secretion of TGFB1 protein]
Amygdalin inhibits the reaction [Ovalbumin results in increased secretion of TGFB1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased secretion of TGFB1 protein]
CTD PMID:36457260 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Vim vimentin multiple interactions EXP
ISO
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:36457260 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
4-methylumbelliferyl beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gaa glucosidase, alpha, acid multiple interactions
increases metabolic processing
ISO GAA gene SNP inhibits the reaction [GAA protein results in increased metabolism of 4-methylumbelliferyl glucoside] CTD PMID:21963784 NCBI chr11:119,158,789...119,176,284
Ensembl chr11:119,158,713...119,176,280
JBrowse link
albiflorin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects expression ISO albiflorin affects the expression of DRD2 CTD PMID:26475043 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A affects expression ISO albiflorin affects the expression of HTR1A CTD PMID:26475043 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A affects expression ISO albiflorin affects the expression of HTR2A CTD PMID:26475043 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 multiple interactions ISO Albiflorin inhibits the reaction [oxidized LDL increases phosphorylation of MAP3K7 protein in umbilical vein endothelial cells] RGD PMID:35601145 RGD:155804296 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 affects expression ISO albiflorin affects the expression of SLC6A3 CTD PMID:26475043 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
JBrowse link
G Th tyrosine hydroxylase affects expression ISO albiflorin affects the expression of TH CTD PMID:26475043 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
amikacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP-binding cassette, sub-family C member 3 decreases expression ISO Amikacin results in decreased expression of ABCC3 mRNA CTD PMID:27765674 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 decreases expression ISO Amikacin results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Casr calcium-sensing receptor increases activity ISO Amikacin results in increased activity of CASR protein CTD PMID:19884751 NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP
ISO
Amikacin results in decreased activity of CAT protein
cefepime inhibits the reaction [Amikacin results in decreased activity of CAT protein]
CTD PMID:18781908 PMID:23416261 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 decreases expression ISO Amikacin results in decreased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Amikacin results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Amikacin results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il24 interleukin 24 decreases expression ISO Amikacin results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO Amikacin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Amikacin results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Amikacin results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 decreases expression ISO Amikacin results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Amikacin results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Tyr tyrosinase decreases activity ISO Amikacin results in decreased activity of TYR protein CTD PMID:23416261 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
apigenin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gypa glycophorin A increases expression ISO apigetrin results in increased expression of GYPA protein CTD PMID:25058688 NCBI chr 8:81,220,674...81,237,414
Ensembl chr 8:81,220,410...81,237,171
JBrowse link
asperuloside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 multiple interactions EXP [lipopolysaccharide, E coli O55-B5 co-treated with asperuloside] results in increased expression of HMOX1 protein; asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein] CTD PMID:33974900 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il10 interleukin 10 multiple interactions EXP asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein] CTD PMID:33974900 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il6 interleukin 6 multiple interactions EXP asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein] CTD PMID:33974900 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP asperuloside inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:33974900 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
multiple interactions
EXP asperuloside affects the localization of NFE2L2 protein
[asperuloside co-treated with Dextran Sulfate] results in increased expression of NFE2L2 protein; [lipopolysaccharide, E coli O55-B5 co-treated with asperuloside] results in increased expression of NFE2L2 protein; asperuloside affects the reaction [NFE2L2 protein affects the expression of NQO1 mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of NFE2L2 protein]
CTD PMID:33974900 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP asperuloside affects the reaction [NFE2L2 protein affects the expression of NQO1 mRNA] CTD PMID:33974900 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP asperuloside inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein] CTD PMID:33974900 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; asperuloside inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:16508180 PMID:33974900 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
calycosin-7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO
EXP
calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA; calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein]
CTD PMID:36812960 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
EXP
ISO
calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA; calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein]
CTD PMID:36812960 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
ISO
EXP
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA] CTD PMID:36812960 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase decreases expression EXP
ISO
calycosin-7-O-beta-D-glucoside results in decreased expression of CAT protein CTD PMID:36812960 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Epo erythropoietin increases expression ISO calycosin-7-O-beta-D-glucoside results in increased expression of EPO mRNA CTD PMID:21309574 PMID:37348668 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble decreases expression EXP calycosin-7-O-beta-D-glucoside results in decreased expression of GPT protein CTD PMID:36812960 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
increases expression
ISO calycosin-7-O-beta-D-glucoside results in decreased degradation of and results in increased expression of HIF1A protein modified form; calycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein
calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA; calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A protein
CTD PMID:21309574 PMID:37348668 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Txn1 thioredoxin 1 decreases expression
multiple interactions
EXP
ISO
calycosin-7-O-beta-D-glucoside results in decreased expression of TXN mRNA; calycosin-7-O-beta-D-glucoside results in decreased expression of TXN protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA]
CTD PMID:36812960 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
daidzein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions
ISO daidzin results in increased expression of ACHE mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of ACHE mRNA]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of and results in increased activity of ACHE protein]; daidzin results in increased expression of and results in increased activity of ACHE protein
CTD PMID:31034797 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial multiple interactions ISO daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]; daidzin inhibits the reaction [ALDH2 protein results in increased oxidation of propionaldehyde] CTD PMID:21349255 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 6:72,183,158...72,212,765
Ensembl chr 6:72,183,161...72,212,561
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 7:127,503,245...127,508,836
Ensembl chr 7:127,503,254...127,509,393
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions EXP daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of BDNF protein] CTD PMID:32450180 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bpgm 2,3-bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 7:13,119,885...13,142,812
Ensembl chr 7:13,132,057...13,142,812
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr 1:160,029,171...160,040,391
Ensembl chr 1:160,029,937...160,040,445
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
JBrowse link
G Cat catalase multiple interactions EXP daidzin inhibits the reaction [Pentylenetetrazole results in decreased activity of CAT protein] CTD PMID:32450180 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr16:44,586,141...44,615,341
Ensembl chr16:44,586,099...44,615,341
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr 5:123,390,196...123,465,547
Ensembl chr 5:123,390,165...123,465,547
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 2:70,948,398...70,973,270
Ensembl chr 2:70,948,267...70,973,270
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 3:106,389,745...106,410,346
Ensembl chr 3:106,389,721...106,410,346
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
JBrowse link
G Dpp9 dipeptidylpeptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr17:56,493,674...56,525,927
Ensembl chr17:56,493,807...56,525,905
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 7:133,239,422...133,274,710
Ensembl chr 7:133,239,272...133,274,700
JBrowse link
G Efhd1 EF hand domain containing 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 1:87,192,075...87,238,563
Ensembl chr 1:87,192,085...87,238,561
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr11:102,327,807...102,338,551
Ensembl chr11:102,327,807...102,338,508
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 2:172,187,444...172,197,669
Ensembl chr 2:172,187,485...172,197,669
JBrowse link
G Fam241b family with sequence similarity 241, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr10:61,943,435...61,946,829
Ensembl chr10:61,943,434...61,979,699
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr10:93,871,862...93,981,201
Ensembl chr10:93,871,863...93,981,201
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO daidzin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr14:31,750,739...31,784,161
Ensembl chr14:31,750,946...31,784,154
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 3:146,205,591...146,211,298
Ensembl chr 3:146,205,562...146,211,327
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 7:27,222,686...27,230,605
Ensembl chr 7:27,222,692...27,230,600
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr 1:150,438,251...150,869,568
Ensembl chr 1:150,438,275...150,869,186
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of HMOX1 protein] CTD PMID:32450180 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Il6ra interleukin 6 receptor, alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 3:87,837,602...87,847,994
Ensembl chr 3:87,837,621...87,847,993
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535
JBrowse link
G Kitl kit ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 2:118,644,470...118,667,691
Ensembl chr 2:118,644,484...118,684,438
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 4:134,468,865...134,495,342
Ensembl chr 4:134,468,865...134,495,335
JBrowse link
G Lmod1 leiomodin 1 (smooth muscle) multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr 1:135,252,551...135,295,803
Ensembl chr 1:135,252,545...135,295,803
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 5:31,771,295...31,779,988
Ensembl chr 5:31,754,279...31,821,728
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 3:96,069,287...96,079,034
Ensembl chr 3:96,069,321...96,079,034
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr19:37,887,484...38,032,025
Ensembl chr19:37,887,484...38,032,025
JBrowse link
G Nefh neurofilament, heavy polypeptide increases expression ISO daidzin results in increased expression of NEFH mRNA; daidzin results in increased expression of NEFH protein CTD PMID:31034797 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nefl neurofilament, light polypeptide increases expression ISO daidzin results in increased expression of NEFL mRNA; daidzin results in increased expression of NEFL protein CTD PMID:31034797 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554
JBrowse link
G Pgr progesterone receptor increases expression ISO daidzin results in increased expression of PGR protein CTD PMID:17142977 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Prima1 proline rich membrane anchor 1 multiple interactions
increases expression
ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of PRIMA1 mRNA] CTD PMID:31034797 NCBI chr12:103,160,712...103,208,967
Ensembl chr12:103,163,167...103,208,409
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Prpf40a pre-mRNA processing factor 40A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 2:53,024,714...53,081,450
Ensembl chr 2:53,024,716...53,081,714
JBrowse link
G Pspc1 paraspeckle protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr14:56,959,898...57,015,775
Ensembl chr14:56,958,167...57,015,773
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 9:110,551,132...110,576,213
Ensembl chr 9:110,551,153...110,576,213
JBrowse link
G Rassf5 Ras association (RalGDS/AF-6) domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr 1:131,104,147...131,172,915
Ensembl chr 1:131,104,147...131,172,995
JBrowse link
G Rgs22 regulator of G-protein signalling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr15:35,960,664...36,140,718
Ensembl chr15:36,009,625...36,140,546
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr13:51,562,654...51,576,833
Ensembl chr13:51,562,675...51,576,833
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr 5:113,955,859...113,970,576
Ensembl chr 5:113,956,597...113,970,705
JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 4:59,805,137...59,904,740
Ensembl chr 4:59,805,840...59,904,737
JBrowse link
G Ssc5d scavenger receptor cysteine rich family, 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 7:4,928,820...4,947,827
Ensembl chr 7:4,928,784...4,947,825
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr 5:135,776,074...135,807,277
Ensembl chr 5:135,776,074...135,807,239
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr12:101,611,705...101,685,178
Ensembl chr12:101,611,702...101,684,782
JBrowse link
G Trp53i11 transformation related protein 53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 2:93,017,694...93,032,102
Ensembl chr 2:93,017,893...93,032,104
JBrowse link
G Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 1:9,788,847...9,818,607
Ensembl chr 1:9,788,847...9,818,607
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP daidzin inhibits the reaction [Pentylenetetrazole results in increased expression of VEGFA protein] CTD PMID:32450180 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
etoposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 0610040J01Rik RIKEN cDNA 0610040J01 gene affects response to substance ISO C4ORF19 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:63,969,833...64,056,968
Ensembl chr 5:63,969,706...64,056,968
JBrowse link
G 6030458C11Rik RIKEN cDNA 6030458C11 gene affects response to substance ISO C5ORF22 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:12,806,012...12,824,767
Ensembl chr15:12,808,263...12,824,735
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A affects response to substance
increases expression
multiple interactions
ISO ABCB1 exon polymorphism affects the susceptibility to Etoposide
Etoposide results in increased expression of ABCB1 mRNA; Etoposide results in increased expression of ABCB1 protein
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide
CTD PMID:12969965 PMID:15239124 PMID:19047049 PMID:19562670 PMID:27570640 More... NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 affects response to substance
multiple interactions
increases expression
decreases uptake
decreases response to substance
ISO
EXP
ABCC1 protein affects the susceptibility to Etoposide
Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]
Etoposide results in increased expression of ABCC1 mRNA
ABCC1 protein results in decreased susceptibility to Etoposide; ABCC1 results in decreased susceptibility to Etoposide
[GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; hesperetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]
CTD PMID:7954421 PMID:8968083 PMID:9334814 PMID:10348353 PMID:10856430 More... NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 affects transport
multiple interactions
ISO ABCC2 protein affects the transport of Etoposide
Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]
CTD PMID:15751272 PMID:15849751 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 decreases response to substance ISO ABCC3 protein results in decreased susceptibility to Etoposide CTD PMID:15884115 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions ISO [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide] CTD PMID:21712253 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Abhd4 abhydrolase domain containing 4 increases expression EXP Etoposide results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr14:54,491,586...54,506,626
Ensembl chr14:54,491,645...54,508,094
JBrowse link
G Abra actin-binding Rho activating protein increases expression ISO Etoposide results in increased expression of ABRA mRNA CTD PMID:29397400 NCBI chr15:41,728,689...41,733,116
Ensembl chr15:41,727,472...41,733,116
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain affects response to substance ISO ACADM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression
decreases expression
ISO Etoposide results in increased expression of ACE2 mRNA
Etoposide results in decreased expression of ACE2 mRNA
CTD PMID:29397400 PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Aco1 aconitase 1 increases expression EXP Etoposide results in increased expression of ACO1 mRNA CTD PMID:25270620 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 affects response to substance ISO ACSL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Acta1 actin alpha 1, skeletal muscle decreases expression ISO Etoposide results in decreased expression of ACTA1 mRNA CTD PMID:29397400 NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490
JBrowse link
G Agrn agrin increases expression ISO Etoposide results in increased expression of AGRN mRNA CTD PMID:17374387 NCBI chr 4:156,249,747...156,281,997
Ensembl chr 4:156,249,747...156,281,945
JBrowse link
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 affects response to substance ISO AHCYL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:107,570,436...107,603,876
Ensembl chr 3:107,570,434...107,603,876
JBrowse link
G Ahi1 Abelson helper integration site 1 increases expression ISO Etoposide results in increased expression of AHI1 protein alternative form CTD PMID:19379585 NCBI chr10:20,827,274...20,956,328
Ensembl chr10:20,828,446...20,956,328
JBrowse link
G Akap12 A kinase anchor protein 12 affects response to substance ISO AKAP12 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases response to substance
increases phosphorylation
multiple interactions
ISO AKT1 protein modified form results in increased susceptibility to Etoposide
Etoposide results in increased phosphorylation of AKT1 protein
Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein; NFKB1 protein affects the reaction [Etoposide results in increased phosphorylation of AKT1 protein]; pepstatin inhibits the reaction [AKT1 protein modified form results in increased susceptibility to Etoposide]; PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:17699715 PMID:17935137 PMID:23396362 PMID:27769712 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alas1 aminolevulinic acid synthase 1 increases expression EXP Etoposide results in increased expression of ALAS1 mRNA CTD PMID:25270620 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression
multiple interactions
ISO Etoposide results in increased expression of ALDH1A1 mRNA; Etoposide results in increased expression of ALDH1A1 protein
FTL protein affects the reaction [Etoposide results in increased expression of ALDH1A1 protein]
CTD PMID:33969609 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Etoposide CTD PMID:15905174 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate affects response to substance
multiple interactions
ISO
EXP
ALDOC protein affects the susceptibility to Etoposide
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein
CTD PMID:16217747 PMID:29733421 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
JBrowse link
G Alppl2 alkaline phosphatase, placental-like 2 affects response to substance ISO ALPG protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:87,014,412...87,023,656
Ensembl chr 1:87,014,416...87,017,650
JBrowse link
G Ank1 ankyrin 1, erythroid increases expression ISO Etoposide results in increased expression of ANK1 mRNA CTD PMID:29397400 NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513
JBrowse link
G Ankrd10 ankyrin repeat domain 10 decreases expression ISO Etoposide results in decreased expression of ANKRD10 mRNA CTD PMID:21527772 NCBI chr 8:11,661,581...11,694,617
Ensembl chr 8:11,661,583...11,685,757
JBrowse link
G Ankrd27 ankyrin repeat domain 27 decreases expression EXP Etoposide results in decreased expression of ANKRD27 mRNA CTD PMID:25270620 NCBI chr 7:35,285,652...35,338,662
Ensembl chr 7:35,285,669...35,338,651
JBrowse link
G Ankrd28 ankyrin repeat domain 28 affects response to substance ISO ANKRD28 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:31,418,687...31,552,374
Ensembl chr14:31,420,725...31,552,608
JBrowse link
G Anxa4 annexin A4 increases expression ISO Etoposide results in increased expression of ANXA4 mRNA CTD PMID:17374387 NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
JBrowse link
G Anxa7 annexin A7 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression EXP Etoposide results in increased expression of APAF1 mRNA CTD PMID:25270620 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 decreases response to substance ISO APEX1 protein results in decreased susceptibility to Etoposide CTD PMID:20856196 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression EXP Etoposide results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 7:30,134,405...30,144,960
Ensembl chr 7:30,134,407...30,144,960
JBrowse link
G Apol8 apolipoprotein L 8 increases expression EXP Etoposide results in increased expression of APOL8 mRNA CTD PMID:25270620 NCBI chr15:77,629,309...77,641,306
Ensembl chr15:77,631,998...77,641,203
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Etoposide results in decreased expression of AQP1 mRNA CTD PMID:25270620 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
JBrowse link
G Ar androgen receptor multiple interactions
increases degradation
ISO calpain inhibitor 2 inhibits the reaction [Etoposide results in increased degradation of AR protein]; CAST inhibits the reaction [Etoposide results in increased degradation of AR protein]; Etoposide inhibits the reaction [Androgens results in increased activity of AR protein]; Etoposide inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18726991 PMID:28377212 PMID:30818834 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Areg amphiregulin increases expression
decreases expression
ISO
EXP
Etoposide results in increased expression of AREG mRNA; Etoposide results in increased expression of AREG protein
Etoposide results in decreased expression of AREG mRNA
CTD PMID:15228094 PMID:25270620 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arg2 arginase type II decreases expression ISO Etoposide results in decreased expression of ARG2 mRNA CTD PMID:29397400 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor beta increases expression ISO Etoposide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases response to substance EXP ARIH1 mutant form results in increased susceptibility to Etoposide CTD PMID:25624349 NCBI chr 9:59,295,837...59,395,469
Ensembl chr 9:59,295,541...59,393,901
JBrowse link
G Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 increases response to substance
decreases expression
ISO ARL6IP5 protein results in increased susceptibility to Etoposide
Etoposide results in decreased expression of ARL6IP5
CTD PMID:19492242 NCBI chr 6:97,187,753...97,210,276
Ensembl chr 6:97,187,650...97,210,276
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [Etoposide results in increased expression of FTL protein] CTD PMID:33969609 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Arsa arylsulfatase A decreases expression EXP Etoposide results in decreased expression of ARSA mRNA CTD PMID:25270620 NCBI chr15:89,356,679...89,361,627
Ensembl chr15:89,356,679...89,361,628
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects response to substance ISO ASAH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Etoposide results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:12663670 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Atf4 activating transcription factor 4 decreases expression EXP Etoposide results in decreased expression of ATF4 mRNA CTD PMID:25270620 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
increases phosphorylation
EXP
ISO
Etoposide results in increased phosphorylation of and results in increased activity of ATM protein
Etoposide results in increased phosphorylation of ATM protein
Etoposide results in increased phosphorylation of and affects the localization of ATM protein; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of and affects the localization of ATM protein]
CTD PMID:22242153 PMID:26259609 PMID:37451322 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Atp13a4 ATPase type 13A4 decreases expression EXP Etoposide results in decreased expression of ATP13A4 mRNA CTD PMID:25270620 NCBI chr16:29,208,685...29,363,682
Ensembl chr16:29,214,671...29,363,682
JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide affects response to substance ISO ATP1A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
JBrowse link
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide decreases expression ISO Etoposide results in decreased expression of ATP1A2 mRNA CTD PMID:29397400 NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
JBrowse link
G Atp1b4 ATPase Na+/K+ transporting, beta 4 polypeptide increases expression ISO Etoposide results in increased expression of ATP1B4 mRNA CTD PMID:29397400 NCBI chr  X:37,404,999...37,425,661
Ensembl chr  X:37,405,061...37,425,646
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr 5:108,581,112...108,582,265
Ensembl chr 5:108,581,110...108,582,314
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression EXP Etoposide results in decreased expression of ATP5PO protein CTD PMID:29733421 NCBI chr16:91,722,111...91,728,518
Ensembl chr16:91,722,102...91,728,575
Ensembl chr16:91,722,102...91,728,575
JBrowse link
G Atp6v0a4 ATPase, H+ transporting, lysosomal V0 subunit A4 affects response to substance ISO ATP6V0A4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:38,025,418...38,101,521
Ensembl chr 6:38,025,418...38,101,521
JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A decreases expression
multiple interactions
EXP Etoposide results in decreased expression of ATP6V1A protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
CTD PMID:29733421 NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide decreases response to substance ISO ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Atr ataxia telangiectasia and Rad3 related increases phosphorylation EXP Etoposide results in increased phosphorylation of ATR protein CTD PMID:22242153 NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Etoposide results in decreased expression of ATXN1 mRNA CTD PMID:24211769 NCBI chr13:45,703,231...46,118,467
Ensembl chr13:45,703,231...46,118,484
JBrowse link
G Aurka aurora kinase A decreases expression EXP Etoposide results in decreased expression of AURKA mRNA CTD PMID:25270620 NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
JBrowse link
G Avpi1 arginine vasopressin-induced 1 affects response to substance ISO AVPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:42,111,714...42,117,432
Ensembl chr19:42,111,712...42,117,498
JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases expression ISO Etoposide results in increased expression of AVPR1A mRNA CTD PMID:29397400 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357
JBrowse link
G Axl AXL receptor tyrosine kinase increases expression ISO Etoposide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G Bace2 beta-site APP-cleaving enzyme 2 affects response to substance ISO BACE2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:97,157,928...97,244,136
Ensembl chr16:97,157,942...97,244,136
JBrowse link
G Bag2 BCL2-associated athanogene 2 affects response to substance ISO BAG2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:33,784,565...33,796,831
Ensembl chr 1:33,784,565...33,796,876
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases response to substance
affects response to substance
multiple interactions
affects expression
ISO
EXP
Etoposide results in increased activity of BAK1 protein
BAK1 protein results in increased susceptibility to Etoposide
BAK1 protein affects the susceptibility to Etoposide
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
Etoposide affects the expression of BAK1 protein
CTD PMID:15215046 PMID:16077961 PMID:17688235 PMID:21745461 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects response to substance ISO BAMBI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression
decreases folding
affects response to substance
ISO
EXP
[ABT-737 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [Cisplatin co-treated with Etoposide] affects the localization of BAX protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [trigonelline co-treated with Etoposide] results in increased expression of BAX protein; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]; Etoposide results in increased activity of and affects the localization of BAX protein; Etoposide results in increased cleavage of and results in increased expression of BAX protein; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] affects the localization of BAX protein]; nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein]
Etoposide results in increased expression of BAX mRNA; Etoposide results in increased expression of BAX protein
BAX protein affects the susceptibility to Etoposide
CTD PMID:9815696 PMID:10620629 PMID:15131059 PMID:16077961 PMID:16120219 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbc3 BCL2 binding component 3 increases expression
multiple interactions
affects response to substance
ISO
EXP
Etoposide results in increased expression of BBC3 mRNA; Etoposide results in increased expression of BBC3 protein
entinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]; Etoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]
BBC3 protein affects the susceptibility to Etoposide
CTD PMID:20477944 PMID:21801448 PMID:25699604 PMID:37956312 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
ISO
EXP
[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [Etoposide co-treated with Ciprofloxacin] results in decreased expression of BCL2 protein; [trigonelline co-treated with Etoposide] results in decreased expression of BCL2 protein; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of BCL2 mRNA; Etoposide results in decreased expression of BCL2 protein
[G(M3) Ganglioside results in increased expression of BCL2 protein] which results in decreased susceptibility to Etoposide; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]
CTD PMID:8840993 PMID:9815696 PMID:12063570 PMID:15917659 PMID:16571667 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions
affects expression
decreases response to substance
ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]
Etoposide affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Etoposide
CTD PMID:8840993 PMID:10620629 PMID:11468182 PMID:15215046 PMID:15917659 More... NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l2 BCL2-like 2 decreases response to substance ISO BCL2L2 results in decreased susceptibility to Etoposide CTD PMID:14973057 NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691
JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624
JBrowse link
G Bdnf brain derived neurotrophic factor increases expression
multiple interactions
ISO Etoposide results in increased expression of BDNF mRNA
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]
CTD PMID:20573984 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression
increases cleavage
ISO CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA] CTD PMID:19426747 PMID:21801448 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Bik BCL2-interacting killer increases response to substance ISO BIK protein results in increased susceptibility to Etoposide CTD PMID:16007125 NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835
JBrowse link
G Bin1 bridging integrator 1 increases response to substance ISO BIN1 protein results in increased susceptibility to Etoposide CTD PMID:21447800 NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790
JBrowse link
G Bin3 bridging integrator 3 affects response to substance ISO BIN3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:70,337,538...70,375,413
Ensembl chr14:70,337,554...70,375,655
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance
decreases response to substance
increases expression
ISO BIRC2 protein affects the susceptibility to Etoposide
BIRC2 protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of BIRC2 mRNA
CTD PMID:10815900 PMID:14970392 PMID:15050749 PMID:16217747 NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases response to substance
decreases expression
multiple interactions
ISO BIRC3 protein results in decreased susceptibility to Etoposide
Etoposide results in decreased expression of BIRC3 mRNA
[Etoposide co-treated with KN 62] results in decreased expression of BIRC3 protein
CTD PMID:14666661 PMID:15050749 PMID:16120219 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases response to substance
increases expression
ISO [FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; BIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Estradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]
BIRC5 protein results in decreased susceptibility to Etoposide
CTD PMID:15917659 PMID:16322251 PMID:16364925 PMID:16382892 PMID:19211844 More... NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Etoposide CTD PMID:17437058 NCBI chr 2:180,570,402...180,575,803
Ensembl chr 2:180,570,816...180,575,803
JBrowse link
G Blm Bloom syndrome, RecQ like helicase decreases expression ISO Etoposide results in decreased expression of BLM mRNA CTD PMID:24211769 NCBI chr 7:80,104,839...80,184,896
Ensembl chr 7:80,104,481...80,184,867
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Brca1 breast cancer 1, early onset multiple interactions
increases expression
decreases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]; pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of BRCA1 protein]
Etoposide results in increased expression of BRCA1 protein
Etoposide results in decreased expression of BRCA1 mRNA
CTD PMID:15607317 PMID:16417649 PMID:26259609 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression EXP Etoposide results in increased expression of BSCL2 mRNA CTD PMID:22003191 PMID:25270620 NCBI chr19:8,814,831...8,826,047
Ensembl chr19:8,814,831...8,826,047
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions
increases expression
EXP
ISO
TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]
Etoposide results in increased expression of BTG2 mRNA; Etoposide results in increased expression of BTG2 protein
CTD PMID:21382384 PMID:22003191 PMID:24211769 PMID:27358234 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
JBrowse link
G Btg3 BTG anti-proliferation factor 3 decreases expression ISO Etoposide results in decreased expression of BTG3 mRNA CTD PMID:24211769 NCBI chr16:78,156,748...78,174,069
Ensembl chr16:78,129,525...78,174,080
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase decreases expression ISO Etoposide results in decreased expression of BUB1 mRNA CTD PMID:16120219 NCBI chr 2:127,642,117...127,673,790
Ensembl chr 2:127,643,036...127,673,785
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase decreases expression ISO Etoposide results in decreased expression of BUB1B mRNA CTD PMID:16120219 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072
JBrowse link
G C1qbp complement component 1, q subcomponent binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Etoposide CTD PMID:25354864 NCBI chr11:70,868,672...70,873,852
Ensembl chr11:70,868,662...70,873,852
JBrowse link
G Cab39 calcium binding protein 39 decreases expression ISO Etoposide results in decreased expression of CAB39 mRNA CTD PMID:17374387 NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297
JBrowse link
G Cadps2 Ca2+-dependent activator protein for secretion 2 affects response to substance ISO CADPS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:23,262,765...23,840,662
Ensembl chr 6:23,262,772...23,839,420
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions
decreases response to substance
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CALCA protein results in decreased susceptibility to Etoposide] CTD PMID:16222118 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Calm1 calmodulin 1 increases expression ISO Etoposide results in increased expression of CALM1 mRNA CTD PMID:29397400 NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073
JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of CARD10 mRNA] CTD PMID:19426747 NCBI chr15:78,659,323...78,687,261
Ensembl chr15:78,659,338...78,687,242
JBrowse link
G Casp2 caspase 2 increases expression
increases splicing
ISO Etoposide results in increased expression of CASP2 mRNA alternative form
Etoposide results in increased splicing of CASP2 mRNA
CTD PMID:14757846 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp3 caspase 3 affects expression
increases cleavage
multiple interactions
increases activity
increases expression
ISO
EXP
Etoposide affects the expression of CASP3 protein
Etoposide results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [Etoposide co-treated with Mifepristone] results in increased activity of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; [trigonelline co-treated with Etoposide] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; Dehydroascorbic Acid promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Silver results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased expression of CASP3 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
Etoposide results in increased expression of CASP3 protein; Etoposide results in increased expression of CASP3 protein modified form
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Metoclopramide inhibits the reaction [Etoposide results in increased activity of CASP3 protein]
CTD PMID:8840993 PMID:10759716 PMID:12871656 PMID:15215046 PMID:15924153 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO
EXP
[STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
CTD PMID:18056177 PMID:18649362 PMID:20299546 PMID:21801448 PMID:22275372 More... NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance
increases cleavage
increases activity
decreases response to substance
ISO 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; acetyl-leucyl-glutamyl-histidyl-aspartal inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP8 protein; Etoposide results in increased expression of and results in increased cleavage of CASP8 protein; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]
CASP8 protein results in increased susceptibility to Etoposide
CTD PMID:15475000 PMID:21745461 PMID:21801448 PMID:22010212 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
affects expression
ISO [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Etoposide results in increased cleavage of and results in increased activity of CASP9 protein; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; wortmannin promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
Etoposide affects the expression of CASP9 protein
CTD PMID:12925536 PMID:15215046 PMID:16364925 PMID:16799960 PMID:17935137 More... NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Casq2 calsequestrin 2 decreases expression ISO Etoposide results in decreased expression of CASQ2 mRNA CTD PMID:29397400 NCBI chr 3:101,993,731...102,053,830
Ensembl chr 3:101,993,731...102,053,830
JBrowse link
G Cast calpastatin multiple interactions ISO CAST inhibits the reaction [Etoposide results in increased degradation of AR protein] CTD PMID:18726991 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929
JBrowse link
G Cat catalase increases response to substance
multiple interactions
increases activity
ISO CAT results in increased susceptibility to Etoposide
EPO protein inhibits the reaction [Etoposide results in increased activity of CAT protein]
CTD PMID:21689642 PMID:25451571 PMID:29069929 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccdc51 coiled-coil domain containing 51 decreases expression ISO Etoposide results in decreased expression of CCDC51 mRNA CTD PMID:24211769 NCBI chr 9:108,911,564...108,922,431
Ensembl chr 9:108,911,561...108,921,557
JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases response to substance
decreases response to substance
ISO CCDC6 results in increased susceptibility to Etoposide
CCDC6 results in decreased susceptibility to Etoposide
CTD PMID:22363533 PMID:22655027 NCBI chr10:69,932,709...70,029,030
Ensembl chr10:69,932,951...70,029,030
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Etoposide results in increased expression of CCL3 protein CTD PMID:10540334 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO Etoposide affects the expression of and affects the localization of CCNA2 protein
Etoposide results in decreased expression of CCNA2 mRNA; Etoposide results in decreased expression of CCNA2 protein
CTD PMID:16120219 PMID:17390037 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Etoposide results in decreased expression of CCNB1 mRNA; Etoposide results in decreased expression of CCNB1 protein CTD PMID:16120219 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Etoposide results in increased expression of CCND1 mRNA CTD PMID:16120219 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccng1 cyclin G1 increases expression EXP Etoposide results in increased expression of CCNG1 mRNA CTD PMID:25270620 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Etoposide results in increased expression of CCNG2 mRNA CTD PMID:18754885 NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Etoposide results in increased expression of CCS mRNA CTD PMID:21527772 NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr16:87,280,213...87,292,757
Ensembl chr16:87,280,214...87,292,761
JBrowse link
G Cd274 CD274 antigen increases expression ISO Etoposide results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd40lg CD40 ligand multiple interactions
decreases response to substance
ISO CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]
CD40LG protein results in decreased susceptibility to Etoposide
CTD PMID:16545138 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd44 CD44 antigen affects response to substance
multiple interactions
ISO CD44 protein affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]
CTD PMID:15215046 PMID:19047049 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement affects response to substance ISO CD55 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481
JBrowse link
G Cd59b CD59b antigen multiple interactions ISO [Cisplatin co-treated with Etoposide] results in decreased expression of CD59 protein CTD PMID:21826740 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,896,142...103,921,534
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Etoposide results in decreased expression of CDC25A mRNA CTD PMID:24211769 NCBI chr 9:109,704,545...109,722,963
Ensembl chr 9:109,704,647...109,722,963
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Etoposide results in decreased expression of CDC25C mRNA CTD PMID:16120219 NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586
JBrowse link
G Cdc42bpg CDC42 binding protein kinase gamma increases expression EXP Etoposide results in increased expression of CDC42BPG mRNA CTD PMID:25270620 NCBI chr19:6,356,465...6,375,682
Ensembl chr19:6,356,486...6,375,682
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Etoposide results in decreased expression of CDC45 mRNA CTD PMID:16120219 NCBI chr16:18,599,202...18,632,371
Ensembl chr16:18,599,197...18,630,737
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Etoposide results in decreased expression of CDC6 mRNA CTD PMID:16120219 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression
affects response to substance
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein]
CDK2 protein affects the susceptibility to Etoposide
CTD PMID:16217747 PMID:16417649 PMID:20149834 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; entinostat promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [entinostat results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of CDKN1A protein]; KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of CDKN1A protein]
Etoposide results in increased expression of CDKN1A mRNA; Etoposide results in increased expression of CDKN1A protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; Etoposide promotes the reaction [Niacin deficiency results in increased expression of CDKN1A protein]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]
CTD PMID:14601052 PMID:16120219 PMID:16882877 PMID:17516866 PMID:21212465 More... NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression
multiple interactions
ISO Etoposide results in increased expression of CDKN1B protein
wortmannin promotes the reaction [Etoposide results in increased expression of CDKN1B protein]
CTD PMID:17935137 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression
multiple interactions
ISO
EXP
Etoposide results in increased expression of CDKN2A mRNA
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]
CTD PMID:21526190 PMID:23690541 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Cdkn3 cyclin dependent kinase inhibitor 3 decreases expression ISO Etoposide results in decreased expression of CDKN3 mRNA CTD PMID:16120219 NCBI chr14:46,997,912...47,008,987
Ensembl chr14:46,997,998...47,009,126
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Etoposide results in increased expression of CEACAM1 mRNA CTD PMID:17374387 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
increases degradation
ISO Etoposide results in decreased expression of CEBPA mRNA; Etoposide results in decreased expression of CEBPA protein
Etoposide results in increased degradation of CEBPA protein
CTD PMID:19662097 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cebpz CCAAT/enhancer binding protein zeta decreases expression ISO Etoposide results in decreased expression of CEBPZ mRNA CTD PMID:17374387 NCBI chr17:79,226,432...79,244,499
Ensembl chr17:79,226,435...79,244,495
JBrowse link
G Cel carboxyl ester lipase increases expression ISO Etoposide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415
JBrowse link
G Cenpf centromere protein F decreases expression ISO Etoposide results in decreased expression of CENPF mRNA CTD PMID:16120219 NCBI chr 1:189,372,803...189,420,302
Ensembl chr 1:189,372,803...189,420,283
JBrowse link
G Cercam cerebral endothelial cell adhesion molecule increases expression EXP Etoposide results in increased expression of CERCAM mRNA CTD PMID:25270620 NCBI chr 2:29,735,442...29,772,857
Ensembl chr 2:29,759,176...29,772,852
JBrowse link
G Ces1d carboxylesterase 1D increases expression EXP Etoposide results in increased expression of CES1D mRNA CTD PMID:25270620 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2a carboxylesterase 2A increases expression EXP Etoposide results in increased expression of CES2A mRNA CTD PMID:25270620 NCBI chr 8:105,460,635...105,468,266
Ensembl chr 8:105,460,635...105,468,266
JBrowse link
G Ces2e carboxylesterase 2E increases expression EXP Etoposide results in increased expression of CES2E mRNA CTD PMID:25270620 NCBI chr 8:105,652,892...105,661,304
Ensembl chr 8:105,652,892...105,661,304
JBrowse link
G Ces2g carboxylesterase 2G increases expression EXP Etoposide results in increased expression of CES2G mRNA CTD PMID:25270620 NCBI chr 8:105,688,350...105,696,169
Ensembl chr 8:105,688,350...105,696,169
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Etoposide results in increased expression of CFLAR protein CTD PMID:14601052 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP Etoposide results in increased expression of CGREF1 mRNA CTD PMID:25270620 NCBI chr 5:31,090,487...31,102,771
Ensembl chr 5:31,090,487...31,102,935
JBrowse link
G Chac1 ChaC, cation transport regulator 1 decreases expression EXP Etoposide results in decreased expression of CHAC1 mRNA CTD PMID:25270620 NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
JBrowse link
G Chaf1a chromatin assembly factor 1, subunit A decreases expression ISO Etoposide results in decreased expression of CHAF1A mRNA CTD PMID:24211769 NCBI chr17:56,347,404...56,375,027
Ensembl chr17:56,347,439...56,379,289
JBrowse link
G Chek1 checkpoint kinase 1 affects response to substance
multiple interactions
ISO CHEK1 protein affects the susceptibility to Etoposide
TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]
CTD PMID:18698031 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions
EXP
ISO
Etoposide results in increased phosphorylation of CHEK2 protein
4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]
CTD PMID:21186793 PMID:22242153 PMID:26259609 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Chi3l1 chitinase 3 like 1 decreases response to substance ISO CHI3L1 results in decreased susceptibility to Etoposide CTD PMID:20506295 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase decreases expression ISO Etoposide results in decreased expression of CHUK protein CTD PMID:30177839 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases response to substance ISO CIAPIN1 protein results in decreased susceptibility to Etoposide CTD PMID:18389626 NCBI chr 8:95,546,446...95,565,454
Ensembl chr 8:95,546,432...95,564,986
JBrowse link
G Ckm creatine kinase, muscle decreases expression ISO Etoposide results in decreased expression of CKM mRNA CTD PMID:29397400 NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1, ubiquitous affects response to substance ISO CKMT1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:121,188,257...121,194,218
Ensembl chr 2:121,188,195...121,194,218
JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO Etoposide results in decreased expression of COA7 mRNA CTD PMID:24211769 NCBI chr 4:108,185,349...108,197,915
Ensembl chr 4:108,185,337...108,198,741
JBrowse link
G Cobl cordon-bleu WH2 repeat decreases expression EXP Etoposide results in decreased expression of COBL mRNA CTD PMID:25270620 NCBI chr11:12,186,676...12,415,022
Ensembl chr11:12,186,608...12,414,960
JBrowse link
G Col15a1 collagen, type XV, alpha 1 affects response to substance ISO COL15A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:47,207,744...47,313,165
Ensembl chr 4:47,208,161...47,313,167
JBrowse link
G Col4a1 collagen, type IV, alpha 1 decreases expression EXP Etoposide results in decreased expression of COL4A1 mRNA CTD PMID:25270620 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
JBrowse link
G Col9a3 collagen, type IX, alpha 3 affects response to substance ISO COL9A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:180,239,895...180,263,985
Ensembl chr 2:180,239,583...180,263,982
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO Etoposide results in decreased expression of COX6A2 mRNA CTD PMID:29397400 NCBI chr 7:127,804,607...127,805,538
Ensembl chr 7:127,804,607...127,805,559
JBrowse link
G Cps1 carbamoyl-phosphate synthetase 1 affects response to substance ISO CPS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Etoposide results in decreased expression of CPT2 mRNA CTD PMID:24211769 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
JBrowse link
G Crabp2 cellular retinoic acid binding protein II increases expression ISO Etoposide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 3:87,856,000...87,860,679
Ensembl chr 3:87,855,973...87,860,683
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP
ISO
Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein; HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein] CTD PMID:20573984 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crem cAMP responsive element modulator affects response to substance ISO CREM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Crip2 cysteine rich protein 2 increases expression EXP Etoposide results in increased expression of CRIP2 mRNA CTD PMID:25270620 NCBI chr12:113,103,856...113,109,126
Ensembl chr12:113,103,856...113,109,126
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 affects response to substance ISO CSGALNACT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:68,809,433...69,188,270
Ensembl chr 8:68,809,433...69,187,798
JBrowse link
G Cth cystathionine gamma lyase affects response to substance ISO CTH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Etoposide results in decreased expression of CXCL12 mRNA; Etoposide results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression
multiple interactions
ISO Etoposide results in increased expression of CXCL8 mRNA; Etoposide results in increased expression of CXCL8 protein
SB 203580 inhibits the reaction [Etoposide results in increased expression of CXCL8 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Etoposide results in increased expression of CXCL8 protein]
CTD PMID:10540334 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Etoposide affects the localization of CYCS protein CTD PMID:10759716 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]
Etoposide results in increased expression of CYP1A1 mRNA; Etoposide results in increased expression of CYP1A1 protein
CTD PMID:29471073 PMID:31542801 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Etoposide results in increased expression of CYP1A2 mRNA CTD PMID:31542801 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases response to substance ISO CYP26A1 protein results in decreased susceptibility to Etoposide CTD PMID:15703382 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Etoposide results in increased expression of CYP27B1 mRNA CTD PMID:17716971 NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases expression EXP Etoposide results in increased expression of CYP2C29 mRNA CTD PMID:25270620 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 increases expression EXP Etoposide results in increased expression of CYP2C55 mRNA CTD PMID:25270620 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression EXP Etoposide results in decreased expression of CYP2S1 mRNA CTD PMID:25270620 NCBI chr 7:25,501,894...25,515,950
Ensembl chr 7:25,501,900...25,516,338
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases methylation
affects response to substance
ISO CYP3A5 protein results in decreased methylation of Etoposide
CYP3A5 gene polymorphism affects the susceptibility to Etoposide
CTD PMID:8114683 PMID:12969965 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 increases expression EXP Etoposide results in increased expression of CYP3A44 mRNA CTD PMID:25270620 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684
JBrowse link
G Cyren cell cycle regulator of NHEJ affects localization ISO Etoposide affects the localization of CYREN protein alternative form CTD PMID:24610814 NCBI chr 6:34,848,706...34,855,024
Ensembl chr 6:34,848,706...34,854,995
JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein affects response to substance ISO DAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:6,329,269...6,470,196
Ensembl chr15:6,329,269...6,470,193
JBrowse link
G Dapk1 death associated protein kinase 1 increases expression
multiple interactions
ISO Etoposide results in increased expression of DAPK1 protein; Etoposide results in increased expression of DAPK1 protein modified form
DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein]
CTD PMID:30177839 NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression EXP Etoposide results in decreased expression of DBF4 mRNA CTD PMID:25270620 NCBI chr 5:8,446,969...8,472,789
Ensembl chr 5:8,446,973...8,472,716
JBrowse link
G Dbn1 drebrin 1 affects response to substance ISO DBN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:55,621,241...55,635,874
Ensembl chr13:55,621,242...55,635,924
JBrowse link
G Dcaf4 DDB1 and CUL4 associated factor 4 increases expression EXP Etoposide results in increased expression of DCAF4 mRNA CTD PMID:25270620 NCBI chr12:83,567,145...83,588,768
Ensembl chr12:83,567,240...83,588,694
JBrowse link
G Dct dopachrome tautomerase affects response to substance ISO DCT protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects response to substance ISO DDIT4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 increases expression EXP Etoposide results in increased expression of DDR1 mRNA CTD PMID:25270620 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Des desmin decreases expression ISO Etoposide results in decreased expression of DES mRNA CTD PMID:29397400 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance ISO DKK3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:111,715,226...111,758,689
Ensembl chr 7:111,715,224...111,758,264
JBrowse link
G Dmd dystrophin, muscular dystrophy affects response to substance
decreases expression
ISO DMD protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of DMD mRNA
CTD PMID:16217747 PMID:29397400 NCBI chr  X:81,858,244...84,248,656
Ensembl chr  X:81,992,476...84,249,747
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 decreases expression EXP Etoposide results in decreased expression of DMRT1 mRNA CTD PMID:25270620 NCBI chr19:25,483,070...25,581,692
Ensembl chr19:25,482,982...25,581,693
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases response to substance ISO DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dnmt3b DNA methyltransferase 3B decreases response to substance ISO DNMT3B protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions ISO Etoposide promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 2:25,242,302...25,246,365
Ensembl chr 2:25,242,288...25,246,371
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression EXP Etoposide results in decreased expression of DPYSL2 protein CTD PMID:29733421 NCBI chr14:67,040,313...67,148,490
Ensembl chr14:67,040,313...67,106,137
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Etoposide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 7:138,665,917...138,681,711
Ensembl chr 7:138,665,917...138,682,620
JBrowse link
G Dusp2 dual specificity phosphatase 2 affects response to substance ISO DUSP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
JBrowse link
G Dusp4 dual specificity phosphatase 4 affects response to substance
increases expression
ISO DUSP4 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of DUSP4 mRNA
CTD PMID:16217747 PMID:29397400 NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednrb endothelin receptor type B decreases expression EXP Etoposide results in decreased expression of EDNRB mRNA CTD PMID:25270620 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838
JBrowse link
G Efs embryonal Fyn-associated substrate increases expression EXP Etoposide results in increased expression of EFS mRNA CTD PMID:25270620 NCBI chr14:55,154,087...55,164,222
Ensembl chr14:55,153,992...55,163,583
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide CTD PMID:16969495 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfl8 EGF-like domain 8 affects response to substance ISO EGFL8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:34,832,174...34,835,536
Ensembl chr17:34,832,323...34,834,945
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Etoposide results in decreased expression of EGFR mRNA; Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Ei24 etoposide induced 2.4 mRNA increases expression ISO Etoposide results in increased expression of EI24 mRNA CTD PMID:17374387 NCBI chr 9:36,690,449...36,708,630
Ensembl chr 9:36,690,455...36,708,689
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit 2 beta decreases expression EXP Etoposide results in decreased expression of EIF2S2 mRNA CTD PMID:25270620 NCBI chr 2:154,713,330...154,734,826
Ensembl chr 2:154,713,330...154,734,855
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases response to substance ISO
EXP
EIF3A results in increased susceptibility to Etoposide CTD PMID:21610145 NCBI chr19:60,749,554...60,779,131
Ensembl chr19:60,749,555...60,779,096
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Etoposide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171
JBrowse link
G Emp2 epithelial membrane protein 2 affects response to substance ISO EMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:10,099,613...10,131,832
Ensembl chr16:10,099,613...10,131,832
JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Etoposide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 7:45,567,447...45,570,850
Ensembl chr 7:45,567,447...45,570,828
JBrowse link
G En2 engrailed 2 affects response to substance ISO EN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:28,370,694...28,377,195
Ensembl chr 5:28,370,692...28,377,164
JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression EXP Etoposide results in decreased expression of ENO1 protein CTD PMID:29733421 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Etoposide results in decreased expression of ENTPD2 mRNA CTD PMID:25270620 NCBI chr 2:25,285,886...25,291,335
Ensembl chr 2:25,285,886...25,291,333
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1 like 3 affects response to substance ISO EPB41L3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:69,382,642...69,596,986
Ensembl chr17:69,382,678...69,596,984
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression EXP Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384 PMID:25270620 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Epm2aip1 EPM2A interacting protein 1 increases expression ISO Etoposide results in increased expression of EPM2AIP1 mRNA CTD PMID:17374387 NCBI chr 9:111,100,913...111,108,161
Ensembl chr 9:111,100,997...111,108,161
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [Etoposide results in increased activity of CAT protein]; EPO protein results in increased susceptibility to [Organoplatinum Compounds co-treated with Etoposide] CTD PMID:18403296 PMID:29069929 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
decreases response to substance
affects response to substance
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Etoposide]
Etoposide results in decreased expression of ERBB2 mRNA
ERBB2 protein results in decreased susceptibility to Etoposide; ERBB2 results in decreased susceptibility to Etoposide
ERBB2 protein affects the susceptibility to Etoposide
CTD PMID:10327070 PMID:15228094 PMID:21712253 PMID:25866362 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 affects response to substance
decreases expression
ISO ERBB3 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of ERBB3 mRNA
CTD PMID:15228094 PMID:16217747 PMID:29397400 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO Etoposide results in decreased expression of ERBB4 mRNA CTD PMID:15228094 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Ereg epiregulin increases expression ISO Etoposide results in increased expression of EREG mRNA CTD PMID:15228094 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Etoposide inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) increases response to substance
multiple interactions
ISO ESR2 protein results in increased susceptibility to Etoposide
TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]
CTD PMID:20623183 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 affects response to substance ISO ESRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:11,331,933...11,386,783
Ensembl chr 4:11,331,933...11,386,783
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO Etoposide inhibits the reaction [XCT790 results in decreased activity of ESRRA protein]; Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain increases expression
multiple interactions
ISO Etoposide results in increased expression of ETS1 protein
DAPK1 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; ETS1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]
CTD PMID:30177839 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
JBrowse link
G Etv6 ets variant 6 increases response to substance
increases mutagenesis
ISO ETV6 gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of ETV6 gene
CTD PMID:15217836 PMID:28624474 NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121
JBrowse link
G Exoc4 exocyst complex component 4 increases expression EXP Etoposide results in increased expression of EXOC4 mRNA CTD PMID:25270620 NCBI chr 6:33,226,025...33,950,914
Ensembl chr 6:33,226,020...33,950,914
JBrowse link
G F11r F11 receptor increases expression ISO Etoposide results in increased expression of F11R mRNA CTD PMID:29397400 NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171
JBrowse link
G F2r coagulation factor II thrombin receptor affects response to substance ISO F2R protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G F3 coagulation factor III increases expression ISO Etoposide results in increased expression of F3 mRNA CTD PMID:12542493 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Fads3 fatty acid desaturase 3 increases expression ISO Etoposide results in increased expression of FADS3 mRNA CTD PMID:21527772 NCBI chr19:10,018,189...10,037,477
Ensembl chr19:10,018,933...10,037,474
JBrowse link
G Fam171a1 family with sequence similarity 171, member A1 affects response to substance ISO FAM171A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:3,115,261...3,228,843
Ensembl chr 2:3,115,261...3,228,843
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
ISO
EXP
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]; Etoposide results in increased expression of and affects the localization of FAS protein; Lithium inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]
Etoposide results in increased expression of FAS mRNA
Etoposide results in increased expression of FAS mRNA; Etoposide results in increased expression of FAS protein
CTD PMID:12513834 PMID:15475000 PMID:16192531 PMID:29397400 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
increases expression
increases activity
ISO
EXP
[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; Nitric Oxide inhibits the reaction [Etoposide results in increased activity of FASLG promoter]
Etoposide results in increased expression of FASL mRNA
CTD PMID:10811113 PMID:12513834 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase increases expression ISO Etoposide results in increased expression of FASN mRNA CTD PMID:17089011 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fbl fibrillarin affects localization ISO Etoposide analog affects the localization of FBL protein CTD PMID:10942594 NCBI chr 7:27,868,293...27,878,701
Ensembl chr 7:27,869,135...27,878,694
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects response to substance ISO FDFT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
JBrowse link
G Fdxr ferredoxin reductase increases expression ISO Etoposide results in increased expression of FDXR mRNA CTD PMID:17374387 NCBI chr11:115,158,850...115,167,925
Ensembl chr11:115,158,850...115,167,876
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fhl1 four and a half LIM domains 1 affects response to substance ISO FHL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706
JBrowse link
G Fhl2 four and a half LIM domains 2 decreases expression ISO Etoposide results in decreased expression of FHL2 mRNA CTD PMID:29397400 NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144
JBrowse link
G Flnc filamin C, gamma increases expression ISO Etoposide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 6:29,433,150...29,461,888
Ensembl chr 6:29,433,255...29,461,882
JBrowse link
G Fos FBJ osteosarcoma oncogene decreases response to substance
increases expression
multiple interactions
ISO FOS protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of FOS
[Etoposide co-treated with Cyclic AMP] results in increased expression of FOS mRNA; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]
CTD PMID:10711420 PMID:18314485 PMID:23824011 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosl1 fos-like antigen 1 increases expression EXP Etoposide results in increased expression of FOSL1 mRNA CTD PMID:25270620 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Foxf2 forkhead box F2 affects response to substance ISO FOXF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:31,809,686...31,815,390
Ensembl chr13:31,809,799...31,815,386
JBrowse link
G Foxj2 forkhead box J2 decreases expression ISO Etoposide results in decreased expression of FOXJ2 mRNA CTD PMID:24211769 NCBI chr 6:122,797,143...122,822,325
Ensembl chr 6:122,796,873...122,822,325
JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation
multiple interactions
ISO Etoposide results in increased phosphorylation of FOXO1 protein
wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO1 protein]
CTD PMID:17935137 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Foxo3 forkhead box O3 increases phosphorylation
increases response to substance
multiple interactions
ISO Etoposide results in increased phosphorylation of FOXO3 protein
FOXO3 protein results in increased susceptibility to Etoposide
[FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO3 protein]
CTD PMID:17935137 PMID:19211844 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions
increases expression
EXP HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA] CTD PMID:20980392 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G Ftl1 ferritin light polypeptide 1 increases expression
multiple interactions
ISO Etoposide results in increased expression of FTL mRNA; Etoposide results in increased expression of FTL protein
1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in increased expression of FTL protein]; ARNT protein affects the reaction [Etoposide results in increased expression of FTL protein]; Etoposide promotes the reaction [HIF1A protein binds to FTL promoter]; FTL protein affects the reaction [Etoposide results in increased expression of ALDH1A1 protein]; FTL protein affects the reaction [Etoposide results in increased expression of KLF4 protein]; FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein]; HIF1A protein affects the reaction [Etoposide results in increased expression of FTL protein]
CTD PMID:33969609 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
JBrowse link
G Fut8 fucosyltransferase 8 affects response to substance ISO FUT8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:77,284,878...77,522,770
Ensembl chr12:77,284,899...77,523,112
JBrowse link
G Fyn Fyn proto-oncogene affects response to substance
decreases expression
ISO
EXP
FYN protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of FYN mRNA
CTD PMID:16217747 PMID:25270620 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression ISO Etoposide results in decreased expression of FZD1 mRNA CTD PMID:24211769 NCBI chr 5:4,803,839...4,808,216
Ensembl chr 5:4,803,839...4,808,035
JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression EXP Etoposide results in decreased expression of FZD5 mRNA CTD PMID:25270620 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases response to substance
multiple interactions
increases expression
ISO GADD45A protein results in increased susceptibility to Etoposide
IKBKB protein inhibits the reaction [Etoposide results in increased expression of GADD45A protein]
Etoposide results in increased expression of GADD45A mRNA; Etoposide results in increased expression of GADD45A protein
CTD PMID:19003803 PMID:21527772 PMID:29397400 PMID:30177839 PMID:31542801 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Ganab alpha glucosidase 2 alpha neutral subunit multiple interactions
decreases expression
EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein
Etoposide results in decreased expression of GANAB protein
CTD PMID:29733421 NCBI chr19:8,875,440...8,894,098
Ensembl chr19:8,875,435...8,894,036
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Etoposide results in increased expression of GAPDH protein CTD PMID:29733421 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression
ISO Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of GDF15 mRNA; Etoposide results in increased expression of GDF15 protein
CTD PMID:11895857 PMID:16120219 PMID:24211769 PMID:29397400 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases response to substance
EXP GJA1 protein affects the reaction [Simvastatin results in increased susceptibility to Etoposide]; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] CTD PMID:23978459 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression ISO Etoposide results in decreased expression of GJA5 mRNA CTD PMID:29397400 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732
JBrowse link
G Gls2 glutaminase 2 (liver, mitochondrial) increases expression ISO Etoposide results in increased expression of GLS2 mRNA CTD PMID:21527772 PMID:29397400 NCBI chr10:128,030,504...128,045,873
Ensembl chr10:128,030,326...128,045,873
JBrowse link
G Gm20348 predicted gene, 20348 increases expression ISO Etoposide results in increased expression of TP53I3 mRNA CTD PMID:17374387 NCBI chr12:4,860,475...4,867,155
Ensembl chr12:4,860,494...4,867,142
JBrowse link
G Gm40318 predicted gene, 40318 increases response to substance
affects response to substance
ISO S100P protein results in increased susceptibility to Etoposide
S100P protein affects the susceptibility to Etoposide
CTD PMID:16217747 PMID:18636193 NCBI chr 5:36,919,848...36,924,763
Ensembl chr 5:36,919,961...36,924,039
JBrowse link
G Gpihbp1 GPI-anchored HDL-binding protein 1 decreases expression EXP Etoposide results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr15:75,468,479...75,470,062
Ensembl chr15:75,468,477...75,471,330
JBrowse link
G Gpm6b glycoprotein m6b affects response to substance ISO GPM6B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:165,021,911...165,172,028
Ensembl chr  X:165,021,907...165,171,984
JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb increases expression ISO Etoposide results in increased expression of GPNMB mRNA CTD PMID:29397400 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
JBrowse link
G Gpr37 G protein-coupled receptor 37 affects response to substance ISO GPR37 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:25,668,522...25,689,979
Ensembl chr 6:25,665,877...25,690,728
JBrowse link
G Gpsm2 G-protein signalling modulator 2 (AGS3-like, C. elegans) affects response to substance ISO GPSM2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:108,585,954...108,629,637
Ensembl chr 3:108,585,954...108,629,625
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Etoposide results in increased expression of GPX1 mRNA CTD PMID:29397400 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression EXP Etoposide results in increased expression of GPX3 mRNA CTD PMID:25270620 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) increases expression EXP Etoposide results in increased expression of GRIA3 mRNA CTD PMID:25270620 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Etoposide results in decreased expression of GRPEL1 mRNA CTD PMID:24211769 NCBI chr 5:36,622,529...36,631,421
Ensembl chr 5:36,622,342...36,631,424
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
EXP BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of GSK3B protein
CTD PMID:19408126 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm4 glutathione S-transferase, mu 4 affects response to substance ISO GSTM4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions
decreases response to substance
affects response to substance
ISO Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Ethacrynic Acid inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; verlukast inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]
GSTP1 gene polymorphism affects the susceptibility to Etoposide
CTD PMID:10900222 PMID:12969965 PMID:15999103 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 affects expression ISO Etoposide affects the expression of HLA-B mRNA CTD PMID:25811541 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
G H2-Q1 histocompatibility 2, Q region locus 1 affects expression ISO Etoposide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075
JBrowse link
G H2-T23 histocompatibility 2, T region locus 23 affects expression ISO Etoposide affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747
JBrowse link
G H2ax H2A.X variant histone multiple interactions
decreases response to substance
increases expression
increases phosphorylation
ISO
EXP
Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; palbociclib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; pifithrin promotes the reaction [Etoposide results in increased expression of H2AX protein]
H2AX protein results in decreased susceptibility to Etoposide
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide results in increased expression of H2AX protein]; RAD54B protein affects the reaction [Etoposide results in increased expression of H2AX protein]; TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione inhibits the reaction [Etoposide results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Bortezomib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Razoxane inhibits the reaction [Etoposide results in increased expression of H2AX protein]
Etoposide results in increased expression of H2AX protein; Etoposide results in increased expression of H2AX protein modified form
CTD PMID:17875725 PMID:20643100 PMID:20978201 PMID:21555580 PMID:21745461 More... NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Hal histidine ammonia lyase decreases expression EXP Etoposide results in decreased expression of HAL mRNA CTD PMID:25270620 NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions
EXP
ISO
Etoposide results in decreased expression of HAMP mRNA
Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]
CTD PMID:25270620 PMID:25633564 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Etoposide results in increased expression of HBEGF mRNA CTD PMID:15228094 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hbp1 high mobility group box transcription factor 1 decreases expression ISO Etoposide results in decreased expression of HBP1 mRNA CTD PMID:24211769 NCBI chr12:31,976,449...32,000,529
Ensembl chr12:31,976,253...32,000,534
JBrowse link
G Hdac4 histone deacetylase 4 affects response to substance ISO HDAC4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421
JBrowse link
G Heph hephaestin affects response to substance ISO HEPH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:95,499,042...95,618,091
Ensembl chr  X:95,498,965...95,618,091
JBrowse link
G Hic1 hypermethylated in cancer 1 multiple interactions
increases expression
ISO E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr11:75,052,203...75,059,970
Ensembl chr11:75,055,391...75,060,345
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO Etoposide promotes the reaction [HIF1A protein binds to FTL promoter]; HIF1A mutant form inhibits the reaction [Oxygen deficiency results in decreased susceptibility to Etoposide]; HIF1A protein affects the reaction [Etoposide results in increased expression of FTL protein] CTD PMID:23144690 PMID:33969609 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases activity
multiple interactions
decreases response to substance
ISO
EXP
Etoposide results in increased activity of HIPK2 protein
HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein]; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]
HIPK2 results in decreased susceptibility to Etoposide
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]
CTD PMID:20573984 PMID:20980392 NCBI chr 6:38,664,447...38,853,236
Ensembl chr 6:38,671,325...38,853,099
JBrowse link
G Hmces 5-hydroxymethylcytosine (hmC) binding, ES cell specific decreases expression EXP Etoposide results in decreased expression of HMCES mRNA CTD PMID:25270620 NCBI chr 6:87,890,889...87,913,603
Ensembl chr 6:87,890,917...87,913,611
JBrowse link
G Hmg20b high mobility group 20B affects response to substance ISO HMG20B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:81,181,880...81,186,777
Ensembl chr10:81,181,882...81,186,314
JBrowse link
G Hmga2 high mobility group AT-hook 2 affects response to substance ISO HMGA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374
JBrowse link
G Hmgb1 high mobility group box 1 decreases response to substance
increases secretion
ISO HMGB1 protein results in decreased susceptibility to Etoposide
Etoposide results in increased secretion of HMGB1 protein
CTD PMID:27807322 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 decreases expression EXP Etoposide results in decreased expression of HNRNPH2 protein CTD PMID:29733421 NCBI chr  X:133,501,928...133,507,809
Ensembl chr  X:133,501,928...133,507,809
JBrowse link
G Hoxa5 homeobox A5 affects response to substance ISO HOXA5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:52,178,768...52,181,437
Ensembl chr 6:52,178,734...52,181,567
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
JBrowse link
G Hspa2 heat shock protein 2 affects response to substance ISO HSPA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712
JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) increases expression EXP Etoposide results in increased expression of HSPE1 protein CTD PMID:29733421 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 affects response to substance
increases response to substance
multiple interactions
ISO
EXP
HTATIP2 protein affects the susceptibility to Etoposide
HTATIP2 protein results in increased susceptibility to Etoposide
HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]
CTD PMID:16217747 PMID:16799960 NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
JBrowse link
G Htr4 5 hydroxytryptamine (serotonin) receptor 4 affects response to substance ISO HTR4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:62,456,618...62,636,098
Ensembl chr18:62,457,275...62,629,648
JBrowse link
G Ier5 immediate early response 5 increases expression ISO Etoposide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr 1:154,972,113...154,975,382
Ensembl chr 1:154,972,107...154,975,382
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 affects response to substance ISO IFITM1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:140,547,342...140,549,740
Ensembl chr 7:140,547,134...140,549,738
JBrowse link
G Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 increases expression EXP Etoposide results in increased expression of IGDCC4 mRNA CTD PMID:25270620 NCBI chr 9:65,008,246...65,045,225
Ensembl chr 9:65,008,768...65,045,222
JBrowse link
G Igf1r insulin-like growth factor I receptor affects response to substance ISO IGF1R protein affects the susceptibility to Etoposide CTD PMID:15499378 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 affects response to substance ISO IGFBP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888
JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 decreases expression EXP Etoposide results in decreased expression of IGSF11 mRNA CTD PMID:25270620 NCBI chr16:38,712,840...38,847,521
Ensembl chr16:38,713,033...38,847,521
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta affects response to substance
decreases expression
multiple interactions
EXP
ISO
IKBKB protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of IKBKB protein
DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; ETS1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; IKBKB protein inhibits the reaction [Etoposide results in increased expression of GADD45A protein]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein modified form]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein]; TP53 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]
CTD PMID:20159942 PMID:30177839 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il1b interleukin 1 beta increases expression EXP Etoposide results in increased expression of IL1B mRNA CTD PMID:18523641 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 decreases response to substance
multiple interactions
ISO IL4 protein results in decreased susceptibility to Etoposide
[IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide
CTD PMID:10620629 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
EXP
ISO
(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased expression of IL6 mRNA]; (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased secretion of IL6 protein]
Etoposide results in increased expression of IL6 mRNA; Etoposide results in increased expression of IL6 protein
CTD PMID:15135310 PMID:17003255 PMID:18523641 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inka2 inka box actin regulator 2 increases expression EXP Etoposide results in increased expression of INKA2 mRNA CTD PMID:25270620 NCBI chr 3:105,611,915...105,628,158
Ensembl chr 3:105,611,915...105,628,158
JBrowse link
G Insig1 insulin induced gene 1 affects response to substance ISO INSIG1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
JBrowse link
G Ints15 integrator complex subunit 15 decreases expression ISO Etoposide results in decreased expression of INTS15 mRNA CTD PMID:24211769 NCBI chr 5:143,286,827...143,301,147
Ensembl chr 5:143,286,950...143,301,115
JBrowse link
G Ireb2 iron responsive element binding protein 2 multiple interactions
decreases expression
ISO 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in decreased expression of IREB2 protein]
Etoposide results in decreased expression of IREB2 mRNA; Etoposide results in decreased expression of IREB2 protein
CTD PMID:33969609 NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814
JBrowse link
G Irs2 insulin receptor substrate 2 affects response to substance ISO IRS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Irx4 Iroquois homeobox 4 decreases expression ISO Etoposide results in decreased expression of IRX4 mRNA CTD PMID:29397400 NCBI chr13:73,407,708...73,417,741
Ensembl chr13:73,408,598...73,417,727
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Etoposide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253
JBrowse link
G Isg20 interferon-stimulated protein affects response to substance ISO ISG20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 decreases expression ISO Etoposide results in decreased expression of ISG20L2 mRNA CTD PMID:24211769 NCBI chr 3:87,837,602...87,847,994
Ensembl chr 3:87,837,621...87,847,993
JBrowse link
G Itga2b integrin alpha 2b increases expression ISO Etoposide results in increased expression of ITGA2B mRNA CTD PMID:21527772 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itgb3 integrin beta 3 increases response to substance ISO ITGB3 protein results in increased susceptibility to Etoposide CTD PMID:21332719 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 affects response to substance ISO ITPR1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Etoposide co-treated with Cyclic AMP] results in increased expression of JUN mRNA CTD PMID:10711420 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 affects response to substance ISO KCNAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:152,475,201...152,561,991
Ensembl chr 4:152,475,199...152,562,367
JBrowse link
G Kcne3 potassium voltage-gated channel, Isk-related subfamily, gene 3 decreases expression EXP Etoposide results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr 7:99,825,714...99,834,076
Ensembl chr 7:99,825,709...99,834,076
JBrowse link
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 decreases expression ISO Etoposide results in decreased expression of KCNN2 mRNA CTD PMID:29397400 NCBI chr18:45,401,754...45,818,954
Ensembl chr18:45,401,927...45,818,950
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 decreases response to substance
multiple interactions
increases response to substance
ISO KEAP1 protein results in decreased susceptibility to Etoposide
KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]
KEAP1 mRNA results in increased susceptibility to Etoposide
CTD PMID:22684020 PMID:26708503 PMID:27982581 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Kif1a kinesin family member 1A increases expression ISO Etoposide results in increased expression of KIF1A mRNA CTD PMID:21527772 NCBI chr 1:92,943,180...93,029,760
Ensembl chr 1:92,943,186...93,029,673
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Etoposide results in decreased expression of KIF20A mRNA CTD PMID:24211769 NCBI chr18:34,757,677...34,766,330
Ensembl chr18:34,757,666...34,766,330
JBrowse link
G Kif23 kinesin family member 23 decreases expression EXP Etoposide results in decreased expression of KIF23 mRNA CTD PMID:25270620 NCBI chr 9:61,824,559...61,854,078
Ensembl chr 9:61,823,187...61,854,056
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions
EXP Etoposide results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein
CTD PMID:29733421 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) multiple interactions
increases expression
ISO FTL protein affects the reaction [Etoposide results in increased expression of KLF4 protein]
Etoposide results in increased expression of KLF4 mRNA; Etoposide results in increased expression of KLF4 protein
CTD PMID:33969609 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klf5 Kruppel-like transcription factor 5 increases expression ISO Etoposide results in increased expression of KLF5 mRNA CTD PMID:29397400 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Klf6 Kruppel-like transcription factor 6 decreases expression ISO Etoposide results in decreased expression of KLF6 mRNA CTD PMID:24211769 NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
JBrowse link
G Klhl26 kelch-like 26 increases expression EXP Etoposide results in increased expression of KLHL26 mRNA CTD PMID:25270620 NCBI chr 8:70,902,868...70,929,660
Ensembl chr 8:70,902,869...70,929,618
JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A increases response to substance
increases mutagenesis
increases cleavage
ISO KMT2A gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of KMT2A gene
Etoposide results in increased cleavage of KMT2A gene
CTD PMID:14712291 PMID:24086652 PMID:28624474 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
JBrowse link
G Krt19 keratin 19 increases expression ISO Etoposide results in increased expression of KRT19 mRNA CTD PMID:29397400 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
JBrowse link
G Krt80 keratin 80 increases expression ISO Etoposide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr15:101,246,196...101,268,043
Ensembl chr15:101,245,325...101,268,043
JBrowse link
G Kynu kynureninase affects response to substance ISO KYNU protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734
JBrowse link
G Lancl1 LanC (bacterial lantibiotic synthetase component C)-like 1 affects response to substance ISO LANCL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:67,039,676...67,078,049
Ensembl chr 1:67,039,676...67,078,031
JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression EXP Etoposide results in decreased expression of LAP3 mRNA CTD PMID:25270620 NCBI chr 5:45,650,716...45,670,033
Ensembl chr 5:45,650,716...45,670,033
JBrowse link
G Lcn2 lipocalin 2 increases response to substance ISO LCN2 protein results in increased susceptibility to Etoposide CTD PMID:19860839 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Ldb3 LIM domain binding 3 decreases expression ISO Etoposide results in decreased expression of LDB3 mRNA CTD PMID:29397400 NCBI chr14:34,248,656...34,312,276
Ensembl chr14:34,248,560...34,310,639
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 affects response to substance ISO LGALS3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lgals7 lectin, galactose binding, soluble 7 increases expression ISO Etoposide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709
JBrowse link
G Lhx1 LIM homeobox protein 1 multiple interactions
decreases expression
EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA
Etoposide results in decreased expression of LHX1 mRNA
CTD PMID:29733421 NCBI chr11:84,408,801...84,416,360
Ensembl chr11:84,409,110...84,416,361
JBrowse link
G Lhx2 LIM homeobox protein 2 decreases expression ISO Etoposide results in decreased expression of LHX2 mRNA CTD PMID:24211769 NCBI chr 2:38,229,282...38,259,747
Ensembl chr 2:38,229,293...38,259,745
JBrowse link
G Lif leukemia inhibitory factor increases expression ISO Etoposide results in increased expression of LIF mRNA CTD PMID:29397400 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
JBrowse link
G Limch1 LIM and calponin homology domains 1 affects response to substance ISO LIMCH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:66,903,232...67,214,502
Ensembl chr 5:66,903,170...67,214,501
JBrowse link
G Lipa lysosomal acid lipase A affects response to substance ISO LIPA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
JBrowse link
G Lrrc47 leucine rich repeat containing 47 decreases expression ISO Etoposide results in decreased expression of LRRC47 mRNA CTD PMID:24211769 NCBI chr 4:154,096,260...154,105,969
Ensembl chr 4:154,096,188...154,105,970
JBrowse link
G Ltbr lymphotoxin B receptor multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of LTBR mRNA] CTD PMID:19426747 NCBI chr 6:125,283,534...125,291,026
Ensembl chr 6:125,283,534...125,290,848
JBrowse link
G Lxn latexin increases response to substance EXP LXN protein results in increased susceptibility to Etoposide CTD PMID:25341047 NCBI chr 3:67,365,332...67,371,240
Ensembl chr 3:67,365,331...67,371,259
JBrowse link
G Ly6e lymphocyte antigen 6 family member E affects response to substance ISO LY6E protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752
JBrowse link
G Lyz1 lysozyme 1 decreases expression EXP Etoposide results in decreased expression of LYZ1 mRNA CTD PMID:25270620 NCBI chr10:117,123,700...117,128,773
Ensembl chr10:117,123,702...117,128,773
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects response to substance ISO MACF1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:123,243,386...123,581,594
Ensembl chr 4:123,243,426...123,581,331
JBrowse link
G Magea6 MAGE family member A6 affects response to substance ISO MAGEA6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:153,706,891...153,719,070
Ensembl chr  X:153,707,008...153,718,983
JBrowse link
G Man2b1 mannosidase 2, alpha B1 increases expression EXP Etoposide results in increased expression of MAN2B1 mRNA CTD PMID:25270620 NCBI chr 8:85,809,941...85,824,215
Ensembl chr 8:85,809,899...85,824,911
JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 increases expression ISO Etoposide results in increased expression of MAP2K3 mRNA CTD PMID:17374387 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Etoposide results in decreased expression of MAP3K5 mRNA CTD PMID:17374387 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
JBrowse link
G Map7 microtubule-associated protein 7 affects response to substance ISO MAP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:20,024,666...20,157,336
Ensembl chr10:20,024,217...20,157,336
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein] CTD PMID:16014620 PMID:19720055 PMID:26046675 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 increases activity
affects response to substance
multiple interactions
ISO Etoposide results in increased activity of MAPK12 protein
MAPK12 protein affects the susceptibility to Etoposide
[MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide
CTD PMID:21878638 NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein] CTD PMID:16014620 PMID:19720055 PMID:26046675 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 multiple interactions
increases phosphorylation
EXP (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased phosphorylation of MAPKAPK2 protein] CTD PMID:17003255 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Matn2 matrilin 2 affects response to substance ISO MATN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:34,306,827...34,436,388
Ensembl chr15:34,306,823...34,436,419
JBrowse link
G Mbp myelin basic protein affects response to substance ISO MBP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression EXP Etoposide results in increased expression of MCAM mRNA CTD PMID:25270620 NCBI chr 9:44,045,958...44,054,024
Ensembl chr 9:44,045,766...44,054,024
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions
decreases expression
ISO wortmannin promotes the reaction [Etoposide results in decreased expression of MCL1 protein] CTD PMID:17935137 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Etoposide results in decreased expression of MCM10 mRNA CTD PMID:24211769 NCBI chr 2:4,995,535...5,017,602
Ensembl chr 2:4,994,525...5,017,602
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Etoposide results in decreased expression of MCM2 mRNA CTD PMID:16120219 NCBI chr 6:88,860,456...88,875,762
Ensembl chr 6:88,860,456...88,875,762
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Etoposide results in decreased expression of MCM6 mRNA CTD PMID:16120219 NCBI chr 1:128,259,312...128,287,442
Ensembl chr 1:128,259,327...128,287,401
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Etoposide results in decreased expression of MCM7 mRNA CTD PMID:16120219 NCBI chr 5:138,162,845...138,170,675
Ensembl chr 5:138,162,845...138,170,684
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor decreases expression ISO Etoposide results in decreased expression of MCM8 mRNA CTD PMID:16120219 NCBI chr 2:132,658,061...132,686,117
Ensembl chr 2:132,658,061...132,686,117
JBrowse link
G Mdfic MyoD family inhibitor domain containing affects response to substance ISO MDFIC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:15,720,660...15,802,168
Ensembl chr 6:15,720,660...15,802,168
JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein CTD PMID:29733421 NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions
decreases expression
increases phosphorylation
increases expression
decreases response to substance
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of MDM2 protein]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein modified form]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein]; Wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]
Etoposide results in decreased expression of MDM2 protein
Etoposide results in increased expression of MDM2 mRNA; Etoposide results in increased expression of MDM2 protein; Etoposide results in increased expression of MDM2 protein modified form
Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]
MDM2 promoter SNP results in decreased susceptibility to Etoposide
CTD PMID:15459018 PMID:16120219 PMID:17575151 PMID:17935137 PMID:18096571 More... NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Me2 malic enzyme 2, NAD(+)-dependent, mitochondrial decreases expression EXP Etoposide results in decreased expression of ME2 protein CTD PMID:29733421 NCBI chr18:73,898,025...73,949,326
Ensembl chr18:73,902,974...73,948,520
JBrowse link
G Mir135b microRNA 135b increases expression ISO Etoposide results in increased expression of MIR135B mRNA CTD PMID:27570640 NCBI chr 1:132,125,826...132,125,922
Ensembl chr 1:132,125,826...132,125,922
JBrowse link
G Mir139 microRNA 139 increases expression ISO Etoposide results in increased expression of MIR139 mRNA CTD PMID:29397400 NCBI chr 7:101,124,583...101,124,650
Ensembl chr 7:101,124,583...101,124,650
JBrowse link
G Mir182 microRNA 182 increases expression ISO Etoposide results in increased expression of MIR182 mRNA CTD PMID:29397400 NCBI chr 6:30,165,917...30,165,991
Ensembl chr 6:30,165,917...30,165,991
JBrowse link
G Mir196b microRNA 196b increases expression ISO Etoposide results in increased expression of MIR196B mRNA CTD PMID:27570640 NCBI chr 6:52,207,061...52,207,145
Ensembl chr 6:52,207,061...52,207,145
JBrowse link
G Mir34c microRNA 34c increases expression ISO Etoposide results in increased expression of MIR34C mRNA CTD PMID:29397400 NCBI chr 9:51,014,334...51,014,410
Ensembl chr 9:51,014,334...51,014,410
JBrowse link
G Mir654 microRNA 654 increases response to substance ISO MIR654 mRNA results in increased susceptibility to Etoposide CTD PMID:20145152 NCBI chr12:109,689,652...109,689,735
Ensembl chr12:109,689,652...109,689,735
JBrowse link
G Mlana melan-A affects response to substance ISO MLANA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:29,674,956...29,685,847
Ensembl chr19:29,675,224...29,686,034
JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 affects response to substance ISO MLLT11 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:95,125,852...95,139,486
Ensembl chr 3:95,126,446...95,139,482
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) decreases expression
multiple interactions
ISO Etoposide results in decreased expression of MMP1 protein
pifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein]
CTD PMID:18557930 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mocos molybdenum cofactor sulfurase affects response to substance ISO MOCOS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:24,786,538...24,834,634
Ensembl chr18:24,786,748...24,834,632
JBrowse link
G Mpo myeloperoxidase increases metabolic processing ISO MPO protein results in increased metabolism of Etoposide CTD PMID:16841962 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Etoposide results in decreased expression of MPZL1 mRNA CTD PMID:24211769 NCBI chr 1:165,419,745...165,462,144
Ensembl chr 1:165,419,809...165,462,107
JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression
affects expression
ISO Etoposide results in increased expression of MR1 mRNA
Etoposide affects the expression of MR1 mRNA
CTD PMID:21527772 PMID:25811541 NCBI chr 1:155,003,620...155,022,560
Ensembl chr 1:155,003,023...155,022,560
JBrowse link
G Mras muscle and microspikes RAS decreases expression EXP Etoposide results in decreased expression of MRAS mRNA CTD PMID:25270620 NCBI chr 9:99,267,473...99,319,505
Ensembl chr 9:99,267,473...99,319,434
JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression EXP Etoposide results in decreased expression of MRC1 mRNA CTD PMID:25270620 NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868
JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 decreases expression ISO Etoposide results in decreased expression of MRM2 mRNA CTD PMID:24211769 NCBI chr 5:140,313,429...140,317,653
Ensembl chr 5:140,313,429...140,317,653
JBrowse link
G Msc musculin decreases expression EXP Etoposide results in decreased expression of MSC mRNA CTD PMID:25270620 NCBI chr 1:14,823,570...14,826,216
Ensembl chr 1:14,823,570...14,826,216
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO Etoposide results in decreased expression of MSH6 mRNA CTD PMID:24211769 NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
JBrowse link
G mt-Nd4 NADH dehydrogenase 4, mitochondrial increases expression ISO Etoposide results in increased expression of ND4 mRNA CTD PMID:26259609 NCBI chr MT:10,167...11,544
Ensembl chr MT:10,167...11,544
JBrowse link
G Mt2 metallothionein 2 multiple interactions
decreases expression
ISO XAF1 protein affects the reaction [Etoposide results in decreased expression of MT2A protein] CTD PMID:28507149 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase decreases expression EXP Etoposide results in decreased expression of MTHFD2 mRNA CTD PMID:25270620 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of MTOR protein CTD PMID:27769712 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Mtus1 mitochondrial tumor suppressor 1 affects response to substance ISO MTUS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:41,443,949...41,587,318
Ensembl chr 8:41,443,951...41,586,763
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein affects response to substance ISO MXI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:53,298,509...53,361,724
Ensembl chr19:53,298,949...53,364,241
JBrowse link
G Myc myelocytomatosis oncogene decreases expression
increases response to substance
multiple interactions
ISO Etoposide results in decreased expression of MYC; Etoposide results in decreased expression of MYC mRNA
MYC protein results in increased susceptibility to Etoposide
MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
CTD PMID:9454737 PMID:21324178 PMID:21527772 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Mycn v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived multiple interactions
decreases response to substance
ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide
MYCN protein results in decreased susceptibility to Etoposide
CTD PMID:10348353 NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta decreases expression ISO Etoposide results in decreased expression of MYH7 mRNA CTD PMID:29397400 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow decreases expression ISO Etoposide results in decreased expression of MYL2 mRNA CTD PMID:29397400 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535
JBrowse link
G Myl3 myosin, light polypeptide 3 decreases expression ISO Etoposide results in decreased expression of MYL3 mRNA CTD PMID:29397400 NCBI chr 9:110,592,746...110,598,870
Ensembl chr 9:110,570,929...110,598,866
JBrowse link
G Myom2 myomesin 2 decreases expression ISO Etoposide results in decreased expression of MYOM2 mRNA CTD PMID:29397400 NCBI chr 8:15,107,653...15,183,410
Ensembl chr 8:15,107,653...15,183,541
JBrowse link
G Myot myotilin increases expression ISO Etoposide results in increased expression of MYOT mRNA CTD PMID:29397400 NCBI chr18:44,467,126...44,488,795
Ensembl chr18:44,467,141...44,488,791
JBrowse link
G Myt1 myelin transcription factor 1 decreases expression ISO Etoposide results in decreased expression of MYT1 mRNA CTD PMID:16120219 NCBI chr 2:181,405,099...181,469,579
Ensembl chr 2:181,405,125...181,469,590
JBrowse link
G Nabp2 nucleic acid binding protein 2 multiple interactions
increases acetylation
ISO 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Etoposide results in increased acetylation of NABP2 protein] CTD PMID:26170237 NCBI chr10:128,237,263...128,247,426
Ensembl chr10:128,237,264...128,247,361
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects response to substance ISO NAP1L1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:111,308,754...111,334,011
Ensembl chr10:111,309,084...111,334,011
JBrowse link
G Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 decreases expression ISO Etoposide results in decreased expression of NCK2 mRNA CTD PMID:17374387 NCBI chr 1:43,484,643...43,609,678
Ensembl chr 1:43,483,739...43,609,675
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression EXP Etoposide results in decreased expression of NECTIN2 mRNA CTD PMID:25270620 NCBI chr 7:19,450,569...19,483,498
Ensembl chr 7:19,450,569...19,484,408
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 affects response to substance ISO NEDD9 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838
JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 decreases expression ISO Etoposide results in decreased expression of NEK2 mRNA CTD PMID:16120219 NCBI chr 1:191,553,622...191,565,161
Ensembl chr 1:191,553,556...191,565,162
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases response to substance
multiple interactions
ISO NFE2L2 mRNA results in decreased susceptibility to Etoposide; NFE2L2 protein results in decreased susceptibility to Etoposide
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; trigonelline inhibits the reaction [NFE2L2 protein results in decreased susceptibility to Etoposide]
CTD PMID:26708503 PMID:27982581 PMID:33148531 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO NFKB1 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; NFKB1 protein affects the reaction [Etoposide results in increased phosphorylation of AKT1 protein] CTD PMID:23396362 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
increases degradation
ISO wortmannin inhibits the reaction [Etoposide results in increased degradation of NFKBIA protein] CTD PMID:12637521 PMID:17935137 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression EXP Etoposide results in increased expression of NHERF1 mRNA CTD PMID:25270620 NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
JBrowse link
G Niban1 niban apoptosis regulator 1 affects response to substance ISO NIBAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:151,447,215...151,597,690
Ensembl chr 1:151,446,937...151,597,690
JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr16:56,977,028...56,987,695
Ensembl chr16:56,977,028...56,987,704
JBrowse link
G Nmt2 N-myristoyltransferase 2 affects response to substance ISO NMT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:3,285,249...3,329,914
Ensembl chr 2:3,285,249...3,329,914
JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression ISO Etoposide results in increased expression of NOS2 mRNA
Etoposide results in increased expression of NOS2 protein
CTD PMID:15135310 PMID:26259609 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Npas1 neuronal PAS domain protein 1 increases expression ISO Etoposide results in increased expression of NPAS1 mRNA CTD PMID:21527772 NCBI chr 7:16,189,643...16,210,741
Ensembl chr 7:16,189,646...16,211,653
JBrowse link
G Npnt nephronectin increases expression EXP Etoposide results in increased expression of NPNT mRNA CTD PMID:25270620 NCBI chr 3:132,587,506...132,656,052
Ensembl chr 3:132,587,506...132,656,052
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 affects response to substance
increases expression
multiple interactions
ISO
EXP
NQO1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NQO1 mRNA
HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]
CTD PMID:16217747 PMID:20980392 PMID:29397400 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression EXP Etoposide results in decreased expression of NR0B1 mRNA CTD PMID:25270620 NCBI chr  X:85,235,381...85,239,553
Ensembl chr  X:85,235,370...85,239,553
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 affects localization
affects response to substance
multiple interactions
ISO Etoposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Etoposide
Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]
CTD PMID:25914138 NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
affects response to substance
increases expression
ISO Etoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Etoposide results in increased expression of and affects the localization of NR1H3 protein; NR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]
NR1H3 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NR1H3 mRNA
CTD PMID:25914138 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
multiple interactions
increases activity
ISO NR1I2 protein affects the susceptibility to Etoposide
[Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:17279585 PMID:25455453 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Etoposide inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] CTD PMID:30818834 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nrap nebulin-related anchoring protein decreases expression ISO Etoposide results in decreased expression of NRAP mRNA CTD PMID:29397400 NCBI chr19:56,308,473...56,378,466
Ensembl chr19:56,308,467...56,378,469
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Etoposide results in increased expression of NRG1 mRNA CTD PMID:29397400 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 affects response to substance
decreases expression
ISO NRIP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NRIP1 mRNA; Etoposide results in decreased expression of NRIP1 protein
CTD PMID:16217747 PMID:25914138 NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 affects response to substance
decreases expression
ISO
EXP
NUPR1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NUPR1 mRNA
CTD PMID:16217747 PMID:25270620 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Oca2 oculocutaneous albinism II affects response to substance ISO OCA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:55,889,341...56,186,266
Ensembl chr 7:55,889,508...56,186,266
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 decreases expression
multiple interactions
EXP Etoposide results in decreased expression of OGG1 mRNA
wogonin inhibits the reaction [Etoposide results in decreased expression of OGG1 mRNA]
CTD PMID:23872129 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 increases expression EXP Etoposide results in increased expression of P2RX7 mRNA CTD PMID:25270620 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 decreases expression EXP Etoposide results in decreased expression of PABPC1 protein CTD PMID:29733421 NCBI chr15:36,595,902...36,609,825
Ensembl chr15:36,595,905...36,609,912
JBrowse link
G Palb2 partner and localizer of BRCA2 decreases expression ISO Etoposide results in decreased expression of PALB2 mRNA CTD PMID:24211769 NCBI chr 7:121,706,485...121,732,203
Ensembl chr 7:121,706,485...121,732,208
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression EXP Etoposide results in increased expression of PAPSS2 mRNA CTD PMID:25270620 NCBI chr19:32,573,072...32,644,587
Ensembl chr19:32,573,190...32,644,587
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage
multiple interactions
increases degradation
ISO Etoposide results in increased cleavage of PARP1 protein
3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [trigonelline co-treated with Etoposide] results in increased cleavage of PARP1 protein; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]; Nicotine inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; XAF1 protein affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
Niacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
CTD PMID:8840993 PMID:9454737 PMID:12690110 PMID:16014620 PMID:16545138 More... NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pbk PDZ binding kinase affects response to substance ISO PBK protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:66,043,337...66,055,271
Ensembl chr14:66,043,286...66,055,271
JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr15:102,378,974...102,408,503
Ensembl chr15:102,378,974...102,408,496
JBrowse link
G Pcbp4 poly(rC) binding protein 4 decreases expression EXP Etoposide results in decreased expression of PCBP4 mRNA CTD PMID:25270620 NCBI chr 9:106,330,181...106,341,211
Ensembl chr 9:106,330,490...106,341,211
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression EXP Etoposide results in decreased expression of PCK2 mRNA CTD PMID:25270620 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699
JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated decreases expression EXP Etoposide results in decreased expression of PDE2A mRNA CTD PMID:25270620 NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026
JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific affects response to substance ISO PDE4B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456
JBrowse link
G Pdgfc platelet-derived growth factor, C polypeptide affects response to substance ISO PDGFC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:80,943,723...81,121,347
Ensembl chr 3:80,943,723...81,121,347
JBrowse link
G Pdia3 protein disulfide isomerase associated 3 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 decreases expression ISO Etoposide results in decreased expression of PDK1 mRNA CTD PMID:29397400 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 increases expression ISO Etoposide results in increased expression of PDK4 mRNA CTD PMID:29397400 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link
G Pdlim3 PDZ and LIM domain 3 increases expression ISO Etoposide results in increased expression of PDLIM3 mRNA CTD PMID:29397400 NCBI chr 8:46,338,524...46,372,672
Ensembl chr 8:46,338,498...46,372,585
JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor decreases expression ISO Etoposide results in decreased expression of PELO mRNA CTD PMID:24211769 NCBI chr13:115,224,891...115,226,694
Ensembl chr13:115,224,891...115,226,722
JBrowse link
G Perp PERP, TP53 apoptosis effector increases expression EXP Etoposide results in increased expression of PERP mRNA CTD PMID:21382384 PMID:25270620 NCBI chr10:18,720,819...18,732,821
Ensembl chr10:18,720,768...18,732,821
JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase affects response to substance ISO PHGDH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
JBrowse link
G Phlda3 pleckstrin homology like domain, family A, member 3 increases expression EXP Etoposide results in increased expression of PHLDA3 mRNA CTD PMID:25270620 NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A multiple interactions ISO [Cisplatin co-treated with Etoposide] results in increased mutagenesis of PIGA CTD PMID:21826740 NCBI chr  X:163,202,814...163,216,912
Ensembl chr  X:163,202,783...163,216,912
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase, type 1 beta affects response to substance ISO PIP5K1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:24,272,158...24,533,236
Ensembl chr19:24,272,158...24,533,236
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Etoposide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plk1 polo like kinase 1 decreases expression EXP Etoposide results in decreased expression of PLK1 mRNA CTD PMID:25270620 NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096
JBrowse link
G Plk2 polo like kinase 2 increases expression ISO Etoposide results in increased expression of PLK2 mRNA CTD PMID:21527772 NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378
JBrowse link
G Plk3 polo like kinase 3 increases expression ISO Etoposide results in increased expression of PLK3 mRNA CTD PMID:17374387 NCBI chr 4:116,985,852...116,991,244
Ensembl chr 4:116,985,852...116,991,160
JBrowse link
G Plp1 proteolipid protein (myelin) 1 affects response to substance ISO PLP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:135,720,897...135,739,331
Ensembl chr  X:135,723,420...135,740,482
JBrowse link
G Plpp2 phospholipid phosphatase 2 decreases expression EXP Etoposide results in decreased expression of PLPP2 mRNA CTD PMID:25270620 NCBI chr10:79,362,258...79,369,621
Ensembl chr10:79,362,264...79,369,630
JBrowse link
G Pm20d1 peptidase M20 domain containing 1 increases expression EXP Etoposide results in increased expression of PM20D1 mRNA CTD PMID:25270620 NCBI chr 1:131,725,122...131,749,210
Ensembl chr 1:131,725,119...131,749,211
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Etoposide results in increased expression of PMAIP1 mRNA CTD PMID:21801448 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pmel premelanosome protein affects response to substance ISO PMEL protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:128,531,757...128,555,993
Ensembl chr10:128,540,064...128,556,107
JBrowse link
G Pmp2 peripheral myelin protein 2 affects response to substance ISO PMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:10,244,911...10,248,945
Ensembl chr 3:10,244,911...10,248,989
JBrowse link
G Pmp22 peripheral myelin protein 22 affects response to substance ISO PMP22 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
JBrowse link
G Polq polymerase (DNA directed), theta decreases response to substance EXP POLQ results in decreased susceptibility to Etoposide CTD PMID:21883722 NCBI chr16:36,832,104...36,922,321
Ensembl chr16:36,832,148...36,915,779
JBrowse link
G Polr1h RNA polymerase I subunit H decreases response to substance
multiple interactions
ISO POLR1H protein results in decreased susceptibility to Etoposide
Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Etoposide]
CTD PMID:14726695 NCBI chr17:37,265,250...37,269,417
Ensembl chr17:37,265,248...37,269,451
JBrowse link
G Postn periostin, osteoblast specific factor increases expression ISO Etoposide results in increased expression of POSTN mRNA CTD PMID:29397400 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 increases expression ISO Etoposide results in increased expression of POU5F1 mRNA; Etoposide results in increased expression of POU5F1 protein CTD PMID:33969609 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression
multiple interactions
ISO Etoposide results in increased expression of PPARGC1A mRNA
Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein]
CTD PMID:26259609 PMID:30818834 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta increases expression ISO Etoposide results in increased expression of PPARGC1B mRNA CTD PMID:26259609 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
JBrowse link
G Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform increases expression ISO Etoposide results in increased expression of PPM1D protein CTD PMID:25078064 NCBI chr11:85,202,080...85,237,897
Ensembl chr11:85,202,070...85,237,892
JBrowse link
G Ppp1r13l protein phosphatase 1, regulatory subunit 13 like decreases response to substance
multiple interactions
increases expression
ISO PPP1R13L results in decreased susceptibility to Etoposide
Etoposide results in increased expression of and results in increased localization of PPP1R13L protein
Etoposide results in increased expression of PPP1R13L mRNA
CTD PMID:17570360 PMID:19299014 NCBI chr 7:19,093,639...19,112,465
Ensembl chr 7:19,093,674...19,112,458
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Etoposide results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 7:79,944,224...79,966,007
Ensembl chr 7:79,944,198...79,966,007
JBrowse link
G Prdx1 peroxiredoxin 1 decreases expression EXP Etoposide results in decreased expression of PRDX1 protein CTD PMID:29733421 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit increases expression ISO Etoposide results in increased expression of PRKAB1 mRNA CTD PMID:24211769 NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Etoposide results in increased cleavage of and results in increased activity of PRKCD protein CTD PMID:19662097 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Prkcz protein kinase C, zeta increases response to substance ISO PRKCZ protein results in increased susceptibility to Etoposide CTD PMID:21863889 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818
JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide increases phosphorylation
multiple interactions
ISO Etoposide results in increased phosphorylation of PRKDC protein
PRKDC protein promotes the reaction [Etoposide results in increased phosphorylation of SP1 protein]
CTD PMID:17441964 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
JBrowse link
G Prkx protein kinase, X-linked increases expression ISO Etoposide results in increased expression of PRKX mRNA CTD PMID:29397400 NCBI chr  X:76,804,578...76,839,545
Ensembl chr  X:76,805,017...76,839,884
JBrowse link
G Prnp prion protein decreases response to substance ISO PRNP protein results in decreased susceptibility to Etoposide CTD PMID:15386405 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349
JBrowse link
G Procr protein C receptor, endothelial increases expression ISO Etoposide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391
JBrowse link
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 7:140,462,307...140,478,555
Ensembl chr 7:140,461,881...140,478,556
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
increases response to substance
ISO PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Etoposide] CTD PMID:16807353 PMID:17935137 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Etoposide results in increased expression of PTGS2 protein
PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]
CTD PMID:24184161 PMID:26259609 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pus3 pseudouridine synthase 3 decreases expression ISO Etoposide results in decreased expression of PUS3 mRNA CTD PMID:24211769 NCBI chr 9:35,469,856...35,478,697
Ensembl chr 9:35,469,891...35,478,697
JBrowse link
G Pygm muscle glycogen phosphorylase decreases expression ISO Etoposide results in decreased expression of PYGM mRNA CTD PMID:29397400 NCBI chr19:6,434,438...6,448,494
Ensembl chr19:6,434,429...6,448,489
JBrowse link
G Rab17 RAB17, member RAS oncogene family affects response to substance ISO RAB17 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:90,885,855...90,897,395
Ensembl chr 1:90,885,855...90,897,383
JBrowse link
G Rab20 RAB20, member RAS oncogene family affects response to substance ISO RAB20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:11,503,390...11,528,640
Ensembl chr 8:11,503,518...11,528,710
JBrowse link
G Rad51 RAD51 recombinase affects localization ISO Etoposide affects the localization of RAD51 protein CTD PMID:9885240 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein multiple interactions
increases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]
Etoposide results in increased expression of RAD52 mRNA; Etoposide results in increased expression of RAD52 protein
CTD PMID:16417649 PMID:19799994 NCBI chr 6:119,878,781...119,899,789
Ensembl chr 6:119,879,659...119,899,789
JBrowse link
G Rad54b RAD54 homolog B (S. cerevisiae) multiple interactions EXP RAD54B protein affects the reaction [Etoposide results in increased expression of H2AX protein] CTD PMID:33823233 NCBI chr 4:11,558,930...11,615,806
Ensembl chr 4:11,558,922...11,615,805
JBrowse link
G Rad54l RAD54 like (S. cerevisiae) increases expression
multiple interactions
ISO Etoposide results in increased expression of RAD54L protein
BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]
CTD PMID:16417649 NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887
JBrowse link
G Rasip1 Ras interacting protein 1 affects response to substance ISO RASIP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:45,276,961...45,288,516
Ensembl chr 7:45,276,912...45,288,517
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 multiple interactions
increases response to substance
ISO [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; ABT-737 promotes the reaction [RASSF1 results in increased susceptibility to Etoposide] CTD PMID:21880625 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects response to substance
decreases phosphorylation
multiple interactions
ISO RB1 protein affects the susceptibility to Etoposide
Etoposide results in decreased phosphorylation of RB1 protein
[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein]
CTD PMID:9454737 PMID:17640669 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rbm17 RNA binding motif protein 17 decreases response to substance ISO RBM17 protein results in decreased susceptibility to Etoposide CTD PMID:16061639 NCBI chr 2:11,590,250...11,608,061
Ensembl chr 2:11,590,248...11,608,964
JBrowse link
G Rbm34 RNA binding motif protein 34 decreases expression ISO Etoposide results in decreased expression of RBM34 mRNA CTD PMID:24211769 NCBI chr 8:127,673,922...127,697,799
Ensembl chr 8:127,673,922...127,697,821
JBrowse link
G Rcan1 regulator of calcineurin 1 affects response to substance ISO RCAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Retsat retinol saturase (all trans retinol 13,14 reductase) increases expression ISO Etoposide results in increased expression of RETSAT mRNA CTD PMID:21527772 NCBI chr 6:72,575,585...72,584,471
Ensembl chr 6:72,575,458...72,585,408
JBrowse link
G Rfc1 replication factor C (activator 1) 1 decreases expression ISO Etoposide results in decreased expression of RFC1 mRNA CTD PMID:24211769 NCBI chr 5:65,419,195...65,492,988
Ensembl chr 5:65,419,193...65,493,013
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO Etoposide results in increased expression of RGCC mRNA CTD PMID:29397400 NCBI chr14:79,526,190...79,539,075
Ensembl chr14:79,526,196...79,539,085
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of RIPK2 mRNA] CTD PMID:19426747 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO Etoposide results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr16:94,129,281...94,137,794
Ensembl chr16:94,129,279...94,137,794
JBrowse link
G Rnf113a1 ring finger protein 113A1 decreases expression ISO Etoposide results in decreased expression of RNF113A mRNA CTD PMID:24211769 NCBI chr  X:36,454,875...36,456,120
Ensembl chr  X:36,454,898...36,456,120
JBrowse link
G Robo1 roundabout guidance receptor 1 affects response to substance ISO ROBO1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:71,824,406...72,844,379
Ensembl chr16:72,105,194...72,842,983
JBrowse link
G Robo3 roundabout guidance receptor 3 increases expression ISO Etoposide results in increased expression of ROBO3 mRNA CTD PMID:21527772 NCBI chr 9:37,327,341...37,344,730
Ensembl chr 9:37,326,965...37,344,542
JBrowse link
G Ropn1 ropporin, rhophilin associated protein 1 affects response to substance ISO ROPN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:34,470,271...34,498,980
Ensembl chr16:34,470,291...34,498,988
JBrowse link
G Rpl6 ribosomal protein L6 decreases response to substance ISO RPL6 protein results in decreased susceptibility to Etoposide CTD PMID:15846068 NCBI chr 5:121,342,564...121,347,304
Ensembl chr 5:121,342,544...121,347,304
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Etoposide results in increased expression of RPS27L protein CTD PMID:18056458 NCBI chr 9:66,851,906...66,856,804
Ensembl chr 9:66,853,368...66,856,798
JBrowse link
G Rps6 ribosomal protein S6 increases phosphorylation ISO Etoposide results in increased phosphorylation of RPS6 protein CTD PMID:23396362 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649
JBrowse link
G Rras related RAS viral (r-ras) oncogene increases expression ISO Etoposide results in increased expression of RRAS mRNA CTD PMID:21527772 NCBI chr 7:44,665,686...44,671,070
Ensembl chr 7:44,667,385...44,671,071
JBrowse link
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) increases expression ISO Etoposide results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr15:37,924,196...37,961,562
Ensembl chr15:37,924,196...37,961,562
JBrowse link
G Rtkn rhotekin increases expression EXP Etoposide results in increased expression of RTKN mRNA CTD PMID:25270620 NCBI chr 6:83,112,485...83,129,560
Ensembl chr 6:83,112,444...83,129,560
JBrowse link
G Runx1 runt related transcription factor 1 increases response to substance
increases mutagenesis
ISO RUNX1 gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of RUNX1 gene
CTD PMID:15217836 PMID:28624474 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Runx3 runt related transcription factor 3 increases response to substance ISO RUNX3 protein results in increased susceptibility to Etoposide CTD PMID:15756676 NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]] CTD PMID:25914138 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac decreases expression ISO Etoposide results in decreased expression of RYR2 mRNA CTD PMID:29397400 NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831
JBrowse link
G Scn3b sodium channel, voltage-gated, type III, beta increases expression EXP Etoposide results in increased expression of SCN3B mRNA CTD PMID:25270620 NCBI chr 9:40,180,512...40,202,914
Ensembl chr 9:40,180,513...40,202,914
JBrowse link
G Scn4b sodium channel, type IV, beta increases expression ISO Etoposide results in increased expression of SCN4B mRNA CTD PMID:29397400 NCBI chr 9:45,049,922...45,065,453
Ensembl chr 9:45,049,693...45,065,450
JBrowse link
G Sdc1 syndecan 1 increases expression ISO Etoposide results in increased expression of SDC1 mRNA CTD PMID:17374387 NCBI chr12:8,821,396...8,843,716
Ensembl chr12:8,821,323...8,843,715
JBrowse link
G Sdhaf1 succinate dehydrogenase complex assembly factor 1 decreases expression ISO Etoposide results in decreased expression of SDHAF1 mRNA CTD PMID:24211769 NCBI chr 7:30,020,834...30,021,800
Ensembl chr 7:30,020,831...30,023,320
JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 increases expression EXP Etoposide results in increased expression of SERPINE2 mRNA CTD PMID:25270620 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897
JBrowse link
G Sesn1 sestrin 1 increases expression ISO Etoposide results in increased expression of SESN1 mRNA CTD PMID:24211769 NCBI chr10:41,686,570...41,784,432
Ensembl chr10:41,685,931...41,784,420
JBrowse link
G Sfn stratifin increases expression ISO Etoposide results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Slbp stem-loop binding protein decreases expression ISO Etoposide results in decreased expression of SLBP mRNA CTD PMID:24211769 NCBI chr 5:33,797,399...33,809,918
Ensembl chr 5:33,792,296...33,809,918
JBrowse link
G Slc16a6 solute carrier family 16 (monocarboxylic acid transporters), member 6 affects response to substance ISO SLC16A6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:109,341,681...109,366,428
Ensembl chr11:109,341,681...109,364,424
JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 decreases expression ISO Etoposide results in decreased expression of SLC1A5 mRNA CTD PMID:24211769 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199
JBrowse link
G Slc22a18 solute carrier family 22 (organic cation transporter), member 18 affects response to substance ISO SLC22A18 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:143,027,502...143,053,071
Ensembl chr 7:143,027,473...143,053,071
JBrowse link
G Slc27a3 solute carrier family 27 (fatty acid transporter), member 3 affects response to substance ISO SLC27A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:90,292,540...90,298,693
Ensembl chr 3:90,292,546...90,297,245
JBrowse link
G Slc2a6 solute carrier family 2 (facilitated glucose transporter), member 6 increases expression ISO Etoposide results in increased expression of SLC2A6 mRNA CTD PMID:21527772 NCBI chr 2:26,911,375...26,918,011
Ensembl chr 2:26,911,375...26,918,010
JBrowse link
G Slc35f2 solute carrier family 35, member F2 decreases expression EXP Etoposide results in decreased expression of SLC35F2 mRNA CTD PMID:25270620 NCBI chr 9:53,678,733...53,725,445
Ensembl chr 9:53,678,822...53,725,438
JBrowse link
G Slc45a3 solute carrier family 45, member 3 multiple interactions ISO Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of SLC45A3 mRNA] CTD PMID:20601956 NCBI chr 1:131,890,653...131,910,710
Ensembl chr 1:131,890,705...131,910,707
JBrowse link
G Slc4a11 solute carrier family 4, sodium bicarbonate transporter-like, member 11 increases expression EXP Etoposide results in increased expression of SLC4A11 mRNA CTD PMID:25270620 NCBI chr 2:130,526,027...130,539,439
Ensembl chr 2:130,526,033...130,539,439
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 affects response to substance ISO SLC7A11 protein affects the susceptibility to Etoposide CTD PMID:31226288 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 decreases expression EXP Etoposide results in decreased expression of SLC7A3 mRNA CTD PMID:25270620 NCBI chr  X:100,122,752...100,134,058
Ensembl chr  X:100,122,816...100,129,626
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 affects response to substance ISO SLC7A5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 decreases expression ISO Etoposide results in decreased expression of SLC8A1 mRNA CTD PMID:29397400 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Etoposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Etoposide results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A affects response to substance ISO SMPDL3A protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:57,670,640...57,687,926
Ensembl chr10:57,670,431...57,687,926
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
decreases response to substance
ISO Etoposide results in increased expression of SOD2 protein
SOD2 protein results in decreased susceptibility to Etoposide
CTD PMID:10759716 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sohlh1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 decreases expression EXP Etoposide results in decreased expression of SOHLH1 mRNA CTD PMID:29733421 NCBI chr 2:25,733,007...25,737,347
Ensembl chr 2:25,733,007...25,737,260
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 affects response to substance ISO SORBS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:40,280,484...40,502,399
Ensembl chr19:40,283,197...40,502,223
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 affects response to substance ISO SORBS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:45,960,470...46,280,943
Ensembl chr 8:45,960,825...46,280,943
JBrowse link
G Sort1 sortilin 1 affects response to substance ISO SORT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
JBrowse link
G Sox10 SRY (sex determining region Y)-box 10 affects response to substance ISO SOX10 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:79,039,113...79,048,690
Ensembl chr15:79,039,108...79,049,440
JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 multiple interactions ISO FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein] CTD PMID:33969609 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610
JBrowse link
G Sp1 trans-acting transcription factor 1 increases phosphorylation
increases expression
increases activity
multiple interactions
ISO Etoposide results in increased phosphorylation of SP1 protein
Etoposide results in increased expression of SP1 mRNA
Etoposide results in increased activity of SP1 protein
cordycepin inhibits the reaction [Etoposide results in increased activity of SP1 protein]; cordycepin inhibits the reaction [Etoposide results in increased expression of SP1 mRNA]
PRKDC protein promotes the reaction [Etoposide results in increased phosphorylation of SP1 protein]; wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of SP1 protein]
CTD PMID:17441964 PMID:23690541 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO Etoposide results in increased expression of SPATA18 mRNA CTD PMID:21527772 PMID:29397400 NCBI chr 5:73,808,723...73,836,927
Ensembl chr 5:73,808,722...73,836,855
JBrowse link
G Spp1 secreted phosphoprotein 1 affects response to substance
decreases expression
ISO
EXP
SPP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of SPP1 mRNA
CTD PMID:16217747 PMID:25270620 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A affects response to substance ISO SPTSSA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:54,692,159...54,703,357
Ensembl chr12:54,692,177...54,703,358
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression
multiple interactions
EXP
ISO
Etoposide results in increased expression of SRXN1 mRNA; Etoposide results in increased expression of SRXN1 protein
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; TP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]
CTD PMID:22003191 PMID:27358234 PMID:27982581 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases response to substance EXP ST3GAL5 protein results in decreased susceptibility to Etoposide CTD PMID:16571667 NCBI chr 6:72,074,555...72,131,555
Ensembl chr 6:72,074,576...72,131,555
JBrowse link
G St6galnac2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 affects response to substance ISO ST6GALNAC2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:116,567,529...116,586,608
Ensembl chr11:116,566,129...116,585,694
Ensembl chr11:116,566,129...116,585,694
JBrowse link
G St7 suppression of tumorigenicity 7 affects response to substance ISO ST7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:17,693,579...17,943,022
Ensembl chr 6:17,692,932...17,943,024
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide CTD PMID:18649362 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Stc1 stanniocalcin 1 increases expression ISO Etoposide results in increased expression of STC1 mRNA CTD PMID:29397400 NCBI chr14:69,266,738...69,278,850
Ensembl chr14:69,266,687...69,279,253
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression EXP Etoposide results in increased expression of STIP1 protein CTD PMID:29733421 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335
JBrowse link
G Stmn1 stathmin 1 affects response to substance ISO STMN1 affects the susceptibility to Etoposide CTD PMID:17172428 NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154
JBrowse link
G Stmn2 stathmin-like 2 decreases expression EXP Etoposide results in decreased expression of STMN2 mRNA CTD PMID:25270620 NCBI chr 3:8,574,587...8,626,664
Ensembl chr 3:8,574,420...8,626,666
JBrowse link
G Stom stomatin increases expression ISO Etoposide results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 2:35,204,002...35,227,021
Ensembl chr 2:35,203,998...35,226,988
JBrowse link
G Synb syncytin b affects response to substance ISO ERVFRD-1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:69,527,827...69,549,857
Ensembl chr14:69,526,793...69,531,748
JBrowse link
G Sytl1 synaptotagmin-like 1 increases expression EXP Etoposide results in increased expression of SYTL1 mRNA CTD PMID:25270620 NCBI chr 4:132,980,401...132,990,398
Ensembl chr 4:132,980,401...132,990,424
JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) increases expression ISO Etoposide results in increased expression of TAP1 mRNA CTD PMID:17374387 PMID:21527772 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
JBrowse link
G Tax1bp3 Tax1 (human T cell leukemia virus type I) binding protein 3 increases expression ISO Etoposide results in increased expression of TAX1BP3 mRNA CTD PMID:17374387 NCBI chr11:73,067,909...73,072,872
Ensembl chr11:73,067,909...73,073,988
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 increases expression EXP Etoposide results in increased expression of TBC1D8 mRNA CTD PMID:25270620 NCBI chr 1:39,410,576...39,517,860
Ensembl chr 1:39,410,573...39,517,836
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked decreases expression EXP Etoposide results in decreased expression of TBL1X mRNA CTD PMID:25270620 NCBI chr  X:76,553,053...76,706,591
Ensembl chr  X:76,554,619...76,706,589
JBrowse link
G Tbpl1 TATA box binding protein-like 1 affects localization EXP Etoposide affects the localization of TBPL1 protein CTD PMID:17085973 NCBI chr10:22,579,776...22,607,882
Ensembl chr10:22,579,778...22,607,837
JBrowse link
G Tcap titin-cap decreases expression ISO Etoposide results in decreased expression of TCAP mRNA CTD PMID:29397400 NCBI chr11:98,274,637...98,275,779
Ensembl chr11:98,274,637...98,275,779
JBrowse link
G Tcfl5 transcription factor-like 5 (basic helix-loop-helix) affects response to substance ISO TCFL5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:180,263,749...180,284,540
Ensembl chr 2:180,263,749...180,284,501
JBrowse link
G Tcp1 t-complex protein 1 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr17:13,135,216...13,143,954
Ensembl chr17:13,134,588...13,143,954
JBrowse link
G Tdrd3 tudor domain containing 3 affects response to substance ISO TDRD3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:87,647,598...87,782,944
Ensembl chr14:87,654,075...87,782,940
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A affects response to substance ISO TENT5A protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:85,202,492...85,209,203
Ensembl chr 9:85,202,492...85,209,401
JBrowse link
G Tex264 testis expressed gene 264 ER-phagy receptor decreases expression EXP Etoposide results in decreased expression of TEX264 mRNA CTD PMID:25270620 NCBI chr 9:106,535,945...106,563,151
Ensembl chr 9:106,535,945...106,563,126
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression ISO Etoposide results in increased expression of TFAM mRNA CTD PMID:26259609 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
JBrowse link
G Tfap2a transcription factor AP-2, alpha affects response to substance
increases response to substance
ISO TFAP2A protein affects the susceptibility to Etoposide
TFAP2A protein results in increased susceptibility to Etoposide
CTD PMID:16204029 PMID:16217747 NCBI chr13:40,867,278...40,891,715
Ensembl chr13:40,868,778...40,891,852
JBrowse link
G Tfec transcription factor EC decreases expression ISO Etoposide results in decreased expression of TFEC mRNA CTD PMID:24211769 NCBI chr 6:16,830,926...16,898,463
Ensembl chr 6:16,833,372...16,898,440
JBrowse link
G Tff3 trefoil factor 3, intestinal affects response to substance ISO TFF3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:31,344,280...31,348,585
Ensembl chr17:31,344,280...31,348,620
JBrowse link
G Tfpi tissue factor pathway inhibitor affects response to substance ISO TFPI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance ISO TFPI2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO Etoposide results in decreased expression of TFRC mRNA; Etoposide results in decreased expression of TFRC protein
1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in decreased expression of TFRC protein]
CTD PMID:33969609 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
JBrowse link
G Tgds TDP-glucose 4,6-dehydratase affects response to substance ISO TGDS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:118,349,323...118,370,177
Ensembl chr14:118,349,323...118,370,167
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Etoposide results in increased expression of TGFA mRNA CTD PMID:15228094 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 decreases expression EXP Etoposide results in decreased expression of TGIF2 mRNA CTD PMID:25270620 NCBI chr 2:156,681,737...156,697,490
Ensembl chr 2:156,681,927...156,697,490
JBrowse link
G Thbs4 thrombospondin 4 increases expression ISO Etoposide results in increased expression of THBS4 mRNA CTD PMID:29397400 NCBI chr13:92,888,094...92,931,326
Ensembl chr13:92,888,098...92,931,326
JBrowse link
G Tipin timeless interacting protein decreases expression ISO Etoposide results in decreased expression of TIPIN mRNA CTD PMID:24211769 NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706
JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 increases expression EXP Etoposide results in increased expression of TM7SF3 mRNA CTD PMID:25270620 NCBI chr 6:146,503,774...146,536,103
Ensembl chr 6:146,503,850...146,544,322
JBrowse link
G Tmbim4 transmembrane BAX inhibitor motif containing 4 increases expression EXP Etoposide results in increased expression of TMBIM4 mRNA CTD PMID:25270620 NCBI chr10:120,044,731...120,060,802
Ensembl chr10:120,037,495...120,060,822
JBrowse link
G Tmc6 transmembrane channel-like gene family 6 affects response to substance ISO TMC6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:117,656,811...117,673,019
Ensembl chr11:117,656,814...117,673,024
JBrowse link
G Tmem185b transmembrane protein 185B decreases expression ISO Etoposide results in decreased expression of TMEM185B mRNA CTD PMID:24211769 NCBI chr 1:119,453,884...119,456,713
Ensembl chr 1:119,453,890...119,456,713
JBrowse link
G Tmem204 transmembrane protein 204 decreases expression EXP Etoposide results in decreased expression of TMEM204 mRNA CTD PMID:25270620 NCBI chr17:25,276,676...25,300,088
Ensembl chr17:25,276,676...25,302,565
JBrowse link
G Tmem47 transmembrane protein 47 affects response to substance ISO TMEM47 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:80,114,250...80,141,481
Ensembl chr  X:80,114,304...80,141,478
JBrowse link
G Tmem97 transmembrane protein 97 affects response to substance ISO TMEM97 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:78,432,643...78,441,561
Ensembl chr11:78,432,643...78,441,603
JBrowse link
G Tmsb4x thymosin, beta 4, X chromosome multiple interactions
decreases response to substance
ISO TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]
TMSB4X protein results in decreased susceptibility to Etoposide
CTD PMID:16364925 NCBI chr  X:165,990,089...165,996,475
Ensembl chr  X:165,990,089...165,992,311
JBrowse link
G Tnf tumor necrosis factor increases expression EXP
ISO
Etoposide results in increased expression of TNF mRNA CTD PMID:15135310 PMID:18523641 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) increases expression EXP Etoposide results in increased expression of TNFRSF11B mRNA CTD PMID:11459812 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of TNFRSF12A mRNA] CTD PMID:19426747 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) increases expression ISO Etoposide results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a affects response to substance EXP TNFRSF1A protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 decreases expression EXP Etoposide results in decreased expression of TNFSF11 mRNA CTD PMID:11459812 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 increases expression ISO Etoposide results in increased expression of TNFSF9 mRNA CTD PMID:17374387 NCBI chr17:57,412,113...57,414,757
Ensembl chr17:57,412,325...57,414,757
JBrowse link
G Tnks tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase affects response to substance ISO TNKS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:35,296,333...35,432,844
Ensembl chr 8:35,293,614...35,432,844
JBrowse link
G Top2a topoisomerase (DNA) II alpha affects binding
decreases activity
multiple interactions
affects activity
decreases expression
increases response to substance
affects response to substance
decreases response to substance
ISO
EXP
Etoposide binds to TOP2A protein
Etoposide analog results in decreased activity of TOP2A protein; Etoposide metabolite results in decreased activity of TOP2A protein; Etoposide results in decreased activity of TOP2A protein
[Ciprofloxacin binds to TOP2A protein] inhibits the reaction [Etoposide binds to TOP2A protein]; [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide; [MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; delphinidin results in decreased susceptibility to [Etoposide affects the activity of TOP2A protein]; Etoposide metabolite inhibits the reaction [TOP2A protein binds to Nucleic Acids, Nucleotides, and Nucleosides]; Etoposide metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; TOP2A results in decreased susceptibility to [Carboplatin co-treated with Etoposide co-treated with Ifosfamide]; TOP2A results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of TOP2A protein
TOP2A protein results in increased susceptibility to Etoposide
TOP2A protein modified form affects the susceptibility to Etoposide
TOP2A gene mutant form results in decreased susceptibility to Etoposide; TOP2A protein mutant form results in decreased susceptibility to Etoposide
CTD PMID:10856430 PMID:11325482 PMID:11470519 PMID:11531262 PMID:11676865 More... NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
G Top2b topoisomerase (DNA) II beta multiple interactions
decreases activity
affects response to substance
decreases response to substance
decreases expression
increases response to substance
EXP
ISO
TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
Etoposide results in decreased activity of TOP2B protein
TOP2B protein affects the susceptibility to Etoposide
TOP2B protein mutant form results in decreased susceptibility to Etoposide
Etoposide results in decreased expression of TOP2B protein
TOP2B protein mutant form results in increased susceptibility to Etoposide
CTD PMID:10856430 PMID:15322234 PMID:16239602 PMID:17875725 PMID:26198043 More... NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584
JBrowse link
G Top3a topoisomerase (DNA) III alpha decreases expression ISO Etoposide results in decreased expression of TOP3A mRNA CTD PMID:24211769 NCBI chr11:60,629,014...60,668,099
Ensembl chr11:60,630,884...60,668,191
JBrowse link
G Tor1a torsin family 1, member A (torsin A) decreases expression ISO Etoposide results in decreased expression of TOR1A mRNA CTD PMID:24211769 NCBI chr 2:30,850,573...30,857,930
Ensembl chr 2:30,850,639...30,857,945
JBrowse link
G Tpi1 triosephosphate isomerase 1 multiple interactions
increases phosphorylation
ISO CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein] CTD PMID:20149834 NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259
JBrowse link
G Tpp2 tripeptidyl peptidase II multiple interactions
affects localization
ISO
EXP
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide affects the localization of TPP2 protein]; SB 203580 inhibits the reaction [Etoposide affects the localization of TPP2 protein]; U 0126 inhibits the reaction [Etoposide affects the localization of TPP2 protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide affects the localization of TPP2 protein]; Sirolimus promotes the reaction [Etoposide affects the localization of TPP2 protein]; U 0126 inhibits the reaction [Etoposide affects the localization of TPP2 protein]; wortmannin promotes the reaction [Etoposide affects the localization of TPP2 protein]
CTD PMID:20643100 NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression
multiple interactions
ISO
EXP
Etoposide results in increased expression of TPT1 mRNA
TRP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 protein]
Etoposide results in increased expression of TPT1 mRNA; Etoposide results in increased expression of TPT1 protein
TP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]
CTD PMID:24067374 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965
JBrowse link
G Traf2 TNF receptor-associated factor 2 affects response to substance EXP TRAF2 protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952
JBrowse link
G Traj18 T cell receptor alpha joining 18 increases expression EXP Etoposide results in increased expression of STK17A mRNA CTD PMID:21489989 NCBI chr14:54,438,234...54,438,299
Ensembl chr14:54,438,234...54,438,299
JBrowse link
G Trib2 tribbles pseudokinase 2 affects response to substance ISO TRIB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:15,841,726...15,866,963
Ensembl chr12:15,841,728...15,866,923
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression EXP Etoposide results in decreased expression of TRIB3 mRNA CTD PMID:25270620 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trim2 tripartite motif-containing 2 affects response to substance
decreases expression
ISO
EXP
TRIM2 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of TRIM2 mRNA
CTD PMID:16217747 PMID:25270620 NCBI chr 3:84,067,746...84,215,659
Ensembl chr 3:84,067,746...84,214,184
JBrowse link
G Trim38 tripartite motif-containing 38 decreases expression ISO Etoposide results in decreased expression of TRIM38 mRNA CTD PMID:24211769 NCBI chr13:23,962,483...23,975,721
Ensembl chr13:23,953,896...23,975,511
JBrowse link
G Trp53 transformation related protein 53 increases acetylation
affects activity
increases expression
multiple interactions
increases activity
increases phosphorylation
affects response to substance
increases response to substance
ISO
EXP
Etoposide results in increased acetylation of TP53 protein; Etoposide results in increased acetylation of TP53 protein mutant form
Etoposide affects the activity of TP53 protein; Etoposide metabolite affects the activity of TP53 protein
Etoposide results in increased expression of TRP53 protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]; Etoposide results in increased phosphorylation of and results in increased activity of TRP53 protein; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 protein]; TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
Etoposide results in increased activity of TP53 protein
Etoposide results in increased phosphorylation of TP53 protein
TRP53 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of TP53 protein
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of TP53 protein
2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein; [Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; [TP53 protein results in increased susceptibility to Etoposide] which results in decreased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of TP53 protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein]; entinostat promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]; Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]; Etoposide promotes the reaction [entinostat results in increased expression of TP53 protein]; Etoposide promotes the reaction [TP53 protein binds to TNFRSF10B promoter]; Etoposide promotes the reaction [TP53 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol]; Etoposide promotes the reaction [trichostatin A results in increased expression of TP53 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of TP53 protein]; Etoposide results in increased expression of and results in increased acetylation of TP53 protein; Etoposide results in increased phosphorylation of and affects the localization of TP53 protein; Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; NFKB1 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Etoposide results in increased activity of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased acetylation of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]
cordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]; Etoposide promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]; Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein; Niacin deficiency inhibits the reaction [Etoposide results in increased expression of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein]
TP53 protein results in increased susceptibility to Etoposide; TP53 results in increased susceptibility to Etoposide
CTD PMID:9815696 PMID:11895857 PMID:12082016 PMID:15131059 PMID:15459018 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 increases expression
multiple interactions
ISO Etoposide results in increased expression of TP53BP1 protein
pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of TP53BP1 protein]
CTD PMID:26259609 PMID:27358234 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888
JBrowse link
G Trp73 transformation related protein 73 multiple interactions
increases expression
ISO [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]; TP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]
Etoposide results in increased expression of TP73 mRNA; Etoposide results in increased expression of TP73 protein
CTD PMID:17716971 PMID:21801448 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases expression ISO Etoposide results in increased expression of TRPV1 mRNA CTD PMID:29397400 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO Etoposide results in decreased expression of TTK mRNA CTD PMID:16120219 NCBI chr 9:83,716,704...83,754,442
Ensembl chr 9:83,716,742...83,754,442
JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO Etoposide results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 1:75,190,867...75,197,905
Ensembl chr 1:75,190,872...75,196,509
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial decreases expression EXP Etoposide results in decreased expression of TUFM protein CTD PMID:29733421 NCBI chr 7:126,086,445...126,089,903
Ensembl chr 7:126,086,533...126,089,903
JBrowse link
G Txn2 thioredoxin 2 decreases response to substance ISO TXN2 protein results in decreased susceptibility to Etoposide CTD PMID:12080052 NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Etoposide results in increased expression of TXNIP protein CTD PMID:18270325 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
JBrowse link
G Txnl1 thioredoxin-like 1 decreases expression EXP Etoposide results in decreased expression of TXNL1 protein CTD PMID:29733421 NCBI chr18:63,795,872...63,825,535
Ensembl chr18:63,794,165...63,841,872
JBrowse link
G Tyms thymidylate synthase affects response to substance ISO TYMS gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
JBrowse link
G Tyrp1 tyrosinase-related protein 1 affects response to substance ISO TYRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:80,752,360...80,769,973
Ensembl chr 4:80,752,360...80,769,956
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression
multiple interactions
ISO Etoposide results in decreased expression of UBE2C mRNA; Etoposide results in decreased expression of UBE2C protein
[Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]
CTD PMID:17374387 PMID:27129209 NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742
JBrowse link
G Ubl3 ubiquitin-like 3 affects response to substance ISO UBL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:148,441,441...148,489,689
Ensembl chr 5:148,441,445...148,489,599
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) decreases expression ISO Etoposide results in decreased expression of UCP2 mRNA CTD PMID:29397400 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 affects response to substance
increases glucuronidation
ISO UGT1A1 gene polymorphism affects the susceptibility to Etoposide
UGT1A1 protein results in increased glucuronidation of Etoposide
CTD PMID:12969965 PMID:17151191 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Etoposide CTD PMID:17151191 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Unc5c unc-5 netrin receptor C increases response to substance ISO UNC5C results in increased susceptibility to Etoposide CTD PMID:21600761 NCBI chr 3:141,171,360...141,540,685
Ensembl chr 3:141,170,977...141,540,685
JBrowse link
G Upp2 uridine phosphorylase 2 increases expression EXP Etoposide results in increased expression of UPP2 mRNA CTD PMID:25270620 NCBI chr 2:58,456,329...58,685,858
Ensembl chr 2:58,457,310...58,682,983
JBrowse link
G Utp3 UTP3 small subunit processome component decreases expression ISO Etoposide results in decreased expression of UTP3 mRNA CTD PMID:24211769 NCBI chr 5:88,702,321...88,703,949
Ensembl chr 5:88,702,321...88,703,949
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases response to substance
ISO [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide
VCAM1 protein results in decreased susceptibility to Etoposide
CTD PMID:10620629 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vcan versican affects response to substance ISO VCAN protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:89,803,429...89,891,146
Ensembl chr13:89,803,431...89,890,628
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO Etoposide promotes the reaction [VDAC1 protein binds to VDAC1 protein] CTD PMID:20937774 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor multiple interactions
affects response to substance
increases expression
ISO [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; TP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]
VDR gene polymorphism affects the susceptibility to Etoposide; VDR intron polymorphism affects the susceptibility to Etoposide
CTD PMID:12969965 PMID:15713801 PMID:17716971 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Vegfa vascular endothelial growth factor A decreases response to substance ISO VEGFA mRNA results in decreased susceptibility to Etoposide CTD PMID:18494554 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions
decreases response to substance
ISO EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]; PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 increases expression EXP Etoposide results in increased expression of VKORC1 mRNA CTD PMID:25270620 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
G Wif1 Wnt inhibitory factor 1 increases response to substance ISO WIF1 protein results in increased susceptibility to Etoposide CTD PMID:15389810 NCBI chr10:120,869,909...120,936,547
Ensembl chr10:120,869,865...120,936,555
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 affects response to substance ISO WIPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793
JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A increases response to substance ISO WNT3A protein results in increased susceptibility to Etoposide CTD PMID:19864107 NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578
JBrowse link
G Wrn Werner syndrome RecQ like helicase increases response to substance ISO WRN gene mutant form results in increased susceptibility to Etoposide CTD PMID:10725663 NCBI chr 8:33,724,400...33,875,591
Ensembl chr 8:33,724,412...33,875,555
JBrowse link
G Xaf1 XIAP associated factor 1 increases response to substance
increases expression
multiple interactions
ISO XAF1 protein results in increased susceptibility to Etoposide
Etoposide results in increased expression of XAF1 mRNA; Etoposide results in increased expression of XAF1 protein
XAF1 protein affects the reaction [Etoposide results in decreased expression of MT2A protein]; XAF1 protein affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
CTD PMID:15843754 PMID:17570219 PMID:28507149 NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559
JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 multiple interactions
affects response to substance
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]
XRCC1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of XRCC1 mRNA; Etoposide results in increased expression of XRCC1 protein
CTD PMID:26046675 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865
JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 multiple interactions
increases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein] CTD PMID:16417649 NCBI chr 5:25,894,812...25,910,795
Ensembl chr 5:25,894,810...25,910,823
JBrowse link
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 multiple interactions
increases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein] CTD PMID:16417649 NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307
JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 multiple interactions
decreases response to substance
increases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]
XRCC4 results in decreased susceptibility to Etoposide
CTD PMID:16417649 PMID:21785230 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727
JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Etoposide CTD PMID:12384553 NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111
JBrowse link
G Zbtb24 zinc finger and BTB domain containing 24 decreases expression ISO Etoposide results in decreased expression of ZBTB24 mRNA CTD PMID:24211769 NCBI chr10:41,326,354...41,341,578
Ensembl chr10:41,326,379...41,341,570
JBrowse link
G Zfp202 zinc finger protein 202 decreases expression ISO Etoposide results in decreased expression of ZNF202 mRNA CTD PMID:24211769 NCBI chr 9:40,103,612...40,124,900
Ensembl chr 9:40,103,612...40,124,900
JBrowse link
G Zfp365 zinc finger protein 365 increases expression EXP Etoposide results in increased expression of ZFP365 mRNA CTD PMID:25270620 NCBI chr10:67,721,935...67,748,492
Ensembl chr10:67,721,933...67,748,492
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 decreases expression ISO Etoposide results in decreased expression of ZFP36L1 mRNA CTD PMID:24211769 NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787
JBrowse link
G Zfp637 zinc finger protein 637 affects response to substance ISO ZNF32 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:117,818,165...117,822,917
Ensembl chr 6:117,818,141...117,822,917
JBrowse link
G Zfp750 zinc finger protein 750 increases expression EXP Etoposide results in increased expression of ZFP750 mRNA CTD PMID:25270620 NCBI chr11:121,401,802...121,410,168
Ensembl chr11:121,401,804...121,410,159
JBrowse link
G Zfp94 zinc finger protein 94 decreases expression ISO Etoposide results in decreased expression of ZNF45 mRNA CTD PMID:24211769 NCBI chr 7:24,001,129...24,016,091
Ensembl chr 7:24,001,129...24,016,091
JBrowse link
G Zmat3 zinc finger matrin type 3 increases expression ISO Etoposide results in increased expression of ZMAT3 mRNA CTD PMID:29397400 NCBI chr 3:32,388,941...32,419,814
Ensembl chr 3:32,388,941...32,420,163
JBrowse link
genistein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions
ISO genistin results in increased expression of ACHE mRNA
genistin results in increased expression of and results in increased activity of ACHE protein
CTD PMID:27019979 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 6:72,183,158...72,212,765
Ensembl chr 6:72,183,161...72,212,561
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 7:127,503,245...127,508,836
Ensembl chr 7:127,503,254...127,509,393
JBrowse link
G Bpgm 2,3-bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 7:13,119,885...13,142,812
Ensembl chr 7:13,132,057...13,142,812
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr 1:160,029,171...160,040,391
Ensembl chr 1:160,029,937...160,040,445
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr16:44,586,141...44,615,341
Ensembl chr16:44,586,099...44,615,341
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP genistin inhibits the reaction [Lipopolysaccharides results in increased activity of CEBPB protein] CTD PMID:15832817 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr 5:123,390,196...123,465,547
Ensembl chr 5:123,390,165...123,465,547
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 2:70,948,398...70,973,270
Ensembl chr 2:70,948,267...70,973,270
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 3:106,389,745...106,410,346
Ensembl chr 3:106,389,721...106,410,346
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
JBrowse link
G Dpp9 dipeptidylpeptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr17:56,493,674...56,525,927
Ensembl chr17:56,493,807...56,525,905
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 7:133,239,422...133,274,710
Ensembl chr 7:133,239,272...133,274,700
JBrowse link
G Efhd1 EF hand domain containing 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 1:87,192,075...87,238,563
Ensembl chr 1:87,192,085...87,238,561
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr11:102,327,807...102,338,551
Ensembl chr11:102,327,807...102,338,508
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 2:172,187,444...172,197,669
Ensembl chr 2:172,187,485...172,197,669
JBrowse link
G Fam241b family with sequence similarity 241, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr10:61,943,435...61,946,829
Ensembl chr10:61,943,434...61,979,699
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr10:93,871,862...93,981,201
Ensembl chr10:93,871,863...93,981,201
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases expression ISO genistin analog results in increased expression of G6PD mRNA CTD PMID:16719502 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr14:31,750,739...31,784,161
Ensembl chr14:31,750,946...31,784,154
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 3:146,205,591...146,211,298
Ensembl chr 3:146,205,562...146,211,327
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 7:27,222,686...27,230,605
Ensembl chr 7:27,222,692...27,230,600
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr 1:150,438,251...150,869,568
Ensembl chr 1:150,438,275...150,869,186
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Il6ra interleukin 6 receptor, alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 3:87,837,602...87,847,994
Ensembl chr 3:87,837,621...87,847,993
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535
JBrowse link
G Kitl kit ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 2:118,644,470...118,667,691
Ensembl chr 2:118,644,484...118,684,438
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 4:134,468,865...134,495,342
Ensembl chr 4:134,468,865...134,495,335
JBrowse link
G Lmod1 leiomodin 1 (smooth muscle) multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr 1:135,252,551...135,295,803
Ensembl chr 1:135,252,545...135,295,803
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889
JBrowse link
G Ltf lactotransferrin increases expression EXP genistin results in increased expression of LTF mRNA CTD PMID:20049207 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 5:31,771,295...31,779,988
Ensembl chr 5:31,754,279...31,821,728
JBrowse link
G Mt1 metallothionein 1 increases expression ISO genistin analog results in increased expression of MT1X mRNA CTD PMID:16719502 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mt2 metallothionein 2 increases expression ISO genistin analog results in increased expression of MT2A mRNA CTD PMID:16719502 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 3:96,069,287...96,079,034
Ensembl chr 3:96,069,321...96,079,034
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr19:37,887,484...38,032,025
Ensembl chr19:37,887,484...38,032,025
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP genistin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15832817 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression ISO genistin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr12:103,160,712...103,208,967
Ensembl chr12:103,163,167...103,208,409
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Prpf40a pre-mRNA processing factor 40A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 2:53,024,714...53,081,450
Ensembl chr 2:53,024,716...53,081,714
JBrowse link
G Pspc1 paraspeckle protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr14:56,959,898...57,015,775
Ensembl chr14:56,958,167...57,015,773
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP genistin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 9:110,551,132...110,576,213
Ensembl chr 9:110,551,153...110,576,213
JBrowse link
G Rassf5 Ras association (RalGDS/AF-6) domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr 1:131,104,147...131,172,915
Ensembl chr 1:131,104,147...131,172,995
JBrowse link
G Rgs22 regulator of G-protein signalling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr15:35,960,664...36,140,718
Ensembl chr15:36,009,625...36,140,546
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr13:51,562,654...51,576,833
Ensembl chr13:51,562,675...51,576,833
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr 5:113,955,859...113,970,576
Ensembl chr 5:113,956,597...113,970,705
JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 increases expression ISO genistin analog results in increased expression of SLC30A1 mRNA CTD PMID:16719502 NCBI chr 1:191,638,810...191,645,359
Ensembl chr 1:191,638,879...191,645,359
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 4:59,805,137...59,904,740
Ensembl chr 4:59,805,840...59,904,737
JBrowse link
G Ssc5d scavenger receptor cysteine rich family, 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 7:4,928,820...4,947,827
Ensembl chr 7:4,928,784...4,947,825
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr 5:135,776,074...135,807,277
Ensembl chr 5:135,776,074...135,807,239
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr12:101,611,705...101,685,178
Ensembl chr12:101,611,702...101,684,782
JBrowse link
G Trp53i11 transformation related protein 53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 2:93,017,694...93,032,102
Ensembl chr 2:93,017,893...93,032,104
JBrowse link
G Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 1:9,788,847...9,818,607
Ensembl chr 1:9,788,847...9,818,607
JBrowse link
ginsenoside C-K term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein] CTD PMID:21875580 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of CXCR1 protein] CTD PMID:21875580 NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21875580 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ifng interferon gamma decreases expression EXP ginsenoside M1 results in decreased expression of IFNG mRNA CTD PMID:15914323 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il1b interleukin 1 beta decreases expression EXP ginsenoside M1 results in decreased expression of IL1B mRNA CTD PMID:15914323 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 decreases expression EXP ginsenoside M1 results in decreased expression of IL4 mRNA CTD PMID:15914323 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside M1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Itga4 integrin alpha 4 multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 2:79,084,767...79,163,458
Ensembl chr 2:79,085,770...79,163,467
JBrowse link
G Itgal integrin alpha L multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Itgb2 integrin beta 2 multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases secretion ISO ginsenoside M1 results in decreased secretion of MMP9 protein CTD PMID:21875580 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO ginsenoside M1 results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:15802804 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO ginsenoside M1 results in decreased expression of and results in decreased activity of NOS2 protein CTD PMID:15802804 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 multiple interactions ISO [ginsenoside M1 co-treated with Adenosine Triphosphate] results in increased activity of P2RX4 protein; ginsenoside M1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:30545933 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 decreases response to substance EXP P2RX7 gene mutant form results in decreased susceptibility to ginsenoside M1 CTD PMID:30545933 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP
ISO
ginsenoside M1 results in decreased expression of PTGS2 mRNA
ginsenoside M1 results in decreased expression of PTGS2 protein
CTD PMID:15802804 PMID:15914323 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO ginsenoside M1 results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:15802804 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:21875580 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases response to substance
ISO
EXP
ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of CXCR1 protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]
ginsenoside M1 results in decreased expression of TNF mRNA
ginsenoside M1 results in decreased susceptibility to TNF protein
CTD PMID:15914323 PMID:21875580 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:21875580 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
ginsenoside F1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO ginsenoside F1 inhibits the reaction [Galactose results in increased expression of CXCL8 mRNA]; ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of CXCL8 protein] CTD PMID:29412148 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO ginsenoside F1 inhibits the reaction [Galactose affects the localization of RELA protein] CTD PMID:29412148 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
ginsenoside F2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:24380838 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
ginsenoside Rb1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein]; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein] CTD PMID:19781563 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A multiple interactions ISO ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1A mRNA] CTD PMID:34812491 NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1B2 mRNA] CTD PMID:34812491 NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions
increases expression
ISO ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of BMP2 mRNA]
ginsenoside Rb1 results in increased expression of BMP2 mRNA
CTD PMID:27470910 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805
JBrowse link
G Casp3 caspase 3 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Oxidopamine results in increased activity of CASP3 protein] CTD PMID:19781563 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Clcn7 chloride channel, voltage-sensitive 7 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CLCN7 mRNA] CTD PMID:34812491 NCBI chr17:25,352,353...25,381,077
Ensembl chr17:25,352,365...25,381,078
JBrowse link
G Ctsb cathepsin B multiple interactions ISO ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSB mRNA] CTD PMID:34812491 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
JBrowse link
G Ctsd cathepsin D multiple interactions ISO ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSD mRNA] CTD PMID:34812491 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions EXP ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA] CTD PMID:22386813 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; ginsenoside Rb1 results in increased expression of and results in increased activity of HMOX1 protein; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 mRNA; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 protein
CTD PMID:19781563 PMID:25422538 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression
ISO ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of IGF1 mRNA]
ginsenoside Rb1 results in increased expression of IGF1 mRNA
CTD PMID:27470910 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:17655881 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Itgam integrin alpha M multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] CTD PMID:17655881 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Itgb2 integrin beta 2 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGB2 protein] CTD PMID:17655881 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 increases expression ISO ginsenoside Rb1 results in increased expression of KCNE1 CTD PMID:24615935 NCBI chr16:92,142,889...92,156,356
Ensembl chr16:92,142,870...92,156,356
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 affects activity ISO ginsenoside Rb1 affects the activity of KCNH2 protein CTD PMID:15842772 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of LAMP1 mRNA] CTD PMID:34812491 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP ginsenoside Rb1 results in increased expression of MAP2 mRNA CTD PMID:24599032 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 multiple interactions EXP ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:22386813 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
affects localization
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]; [ginsenoside Rb1 co-treated with ginsenoside 20S-protopanaxatriol] results in increased expression of NFE2L2 protein; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]; ginsenoside Rb1 results in increased activity of and results in increased localization of NFE2L2 protein; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]
ginsenoside Rb1 affects the localization of NFE2L2 protein
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] affects the localization of NFE2L2 protein
ginsenoside Rb1 results in increased expression of NFE2L2 mRNA
CTD PMID:19781563 PMID:22780686 PMID:25422538 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 multiple interactions ISO ginsenoside Rb1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:30545933 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801
JBrowse link
G Pgr progesterone receptor increases expression ISO ginsenoside Rb1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP ginsenoside Rb1 inhibits the reaction [TNFSF11 protein affects the localization of RELA protein] CTD PMID:22386813 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Runx2 runt related transcription factor 2 increases expression
multiple interactions
ISO ginsenoside Rb1 results in increased expression of RUNX2 mRNA
ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of RUNX2 mRNA]
CTD PMID:27470910 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions ISO ginsenoside Rb1 binds to and results in decreased activity of SLCO1B3 protein CTD PMID:25297453 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Sqstm1 sequestosome 1 decreases expression
multiple interactions
ISO ginsenoside Rb1 results in decreased expression of SQSTM1 protein
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased expression of SQSTM1 protein]
CTD PMID:34812491 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Tfeb transcription factor EB multiple interactions ISO [ginsenoside Rb1 co-treated with alpha-Chlorohydrin] affects the localization of TFEB protein; ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of TFEB mRNA] CTD PMID:34812491 NCBI chr17:48,047,962...48,103,341
Ensembl chr17:48,047,955...48,103,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
ISO ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of TGFB1 mRNA]
ginsenoside Rb1 results in increased expression of TGFB1 mRNA
CTD PMID:27470910 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of TNF mRNA] CTD PMID:22386813 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions
decreases response to substance
EXP ginsenoside Rb1 inhibits the reaction [TNFSF11 protein affects the localization of RELA protein]; ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of TNF mRNA]
ginsenoside Rb1 results in decreased susceptibility to TNFSF11 protein
CTD PMID:22386813 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
ginsenoside Rb2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression ISO ginsenoside Rb2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Lpl lipoprotein lipase increases secretion
decreases secretion
EXP ginsenoside Rb2 results in increased secretion of LPL protein
ginsenoside Rb2 results in decreased secretion of LPL protein
CTD PMID:8988629 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
ginsenoside Rc term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions ISO ginsenoside Rc binds to and results in decreased activity of SLCO1B3 protein CTD PMID:25297453 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
ginsenoside Rd term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 multiple interactions EXP ginsenoside Rd results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:24599032 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in decreased expression of BCL2 mRNA]; ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of BAX mRNA]; ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CASP3 protein modified form]; ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CYCS mRNA] CTD PMID:26111763 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of BAX mRNA] CTD PMID:26111763 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in decreased expression of BCL2 mRNA] CTD PMID:26111763 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CASP3 protein modified form] CTD PMID:26111763 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase increases expression ISO ginsenoside Rd results in increased expression of CAT protein CTD PMID:9933756 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
multiple interactions
EXP ginsenoside Rd results in increased expression of CDKN1A mRNA
staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CDKN1A mRNA]
CTD PMID:24599032 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Chat choline acetyltransferase increases expression
multiple interactions
EXP ginsenoside Rd results in increased expression of CHAT mRNA; ginsenoside Rd results in increased expression of CHAT protein
staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CHAT mRNA]; staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CHAT protein]
CTD PMID:24599032 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CYCS mRNA] CTD PMID:26111763 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Lpl lipoprotein lipase decreases secretion EXP ginsenoside Rd results in decreased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP ginsenoside Rd results in increased expression of MAP2 mRNA; ginsenoside Rd results in increased expression of MAP2 protein CTD PMID:24599032 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP ginsenoside Rd results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:24599032 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP ginsenoside Rd results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:24599032 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Ngf nerve growth factor increases expression EXP ginsenoside Rd results in increased expression of NGF mRNA CTD PMID:24599032 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) increases expression EXP ginsenoside Rd results in increased expression of NGFR mRNA; ginsenoside Rd results in increased expression of NGFR protein CTD PMID:24599032 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 multiple interactions ISO ginsenoside Rd promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:30545933 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 decreases response to substance EXP P2RX7 gene mutant form results in decreased susceptibility to ginsenoside Rd CTD PMID:30545933 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 increases expression EXP ginsenoside Rd results in increased expression of SLC18A3 mRNA CTD PMID:24599032 NCBI chr14:32,184,394...32,186,807
Ensembl chr14:32,184,395...32,186,807
JBrowse link
G Slc5a7 solute carrier family 5 (choline transporter), member 7 increases expression EXP ginsenoside Rd results in increased expression of SLC5A7 mRNA CTD PMID:24599032 NCBI chr17:54,580,618...54,606,071
Ensembl chr17:54,580,618...54,606,062
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions ISO ginsenoside Rd binds to and results in decreased activity of SLCO1B3 protein CTD PMID:25297453 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
ginsenoside Re term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 increases transport ISO ABCB11 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases transport ISO ABCC1 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases transport ISO ABCC2 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases transport ISO ABCG2 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
multiple interactions
EXP ginsenoside Re results in increased expression of ADIPOQ mRNA
ginsenoside Re results in increased expression of and results in increased secretion of ADIPOQ protein
CTD PMID:23545455 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions
decreases expression
EXP 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; ginsenoside Re affects the reaction [GPX1 protein affects the expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]
ginsenoside Re results in decreased expression of AIF1 protein
CTD PMID:29467000 PMID:36682417 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
increases phosphorylation
EXP
ISO
ginsenoside Re results in increased phosphorylation of and results in increased activity of AKT1 protein
ginsenoside Re results in increased phosphorylation of AKT1 protein
CTD PMID:17878692 PMID:17885204 PMID:24599032 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Ar androgen receptor multiple interactions ISO ginsenoside Re binds to and affects the activity of AR protein CTD PMID:16985185 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Bax BCL2-associated X protein decreases expression
multiple interactions
EXP
ISO
ginsenoside Re results in decreased expression of BAX mRNA; ginsenoside Re results in decreased expression of BAX protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; Acetylcysteine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; Cyclosporine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]
CTD PMID:12674765 PMID:15621629 PMID:29467000 PMID:37308051 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression
multiple interactions
EXP ginsenoside Re results in increased expression of BCL2 mRNA; ginsenoside Re results in increased expression of BCL2 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2 protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]
CTD PMID:15621629 PMID:29467000 PMID:37308051 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions EXP 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2L1 protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2L1 protein] CTD PMID:37308051 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of CASP3 protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; ginsenoside Re results in decreased cleavage of and results in decreased activity of CASP3 protein; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]] CTD PMID:15621629 PMID:23102375 PMID:25523949 PMID:29467000 PMID:37308051 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase multiple interactions EXP ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]] CTD PMID:24430743 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression EXP ginsenoside Re results in increased expression of CDKN1A mRNA CTD PMID:24599032 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Chat choline acetyltransferase increases expression
multiple interactions
EXP ginsenoside Re results in increased expression of CHAT mRNA; ginsenoside Re results in increased expression of CHAT protein
staurosporine aglycone inhibits the reaction [ginsenoside Re results in increased expression of CHAT mRNA]; staurosporine aglycone inhibits the reaction [ginsenoside Re results in increased expression of CHAT protein]
CTD PMID:24599032 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions EXP ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:17885204 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Cldn1 claudin 1 multiple interactions EXP ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] CTD PMID:22849695 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Crp C-reactive protein, pentraxin-related increases expression ISO ginsenoside Re results in increased expression of CRP protein CTD PMID:16797897 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide multiple interactions EXP ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [Phencyclidine results in increased activity of CYBA protein] CTD PMID:29037473 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 increases expression ISO ginsenoside Re results in increased expression of CYP8B1 mRNA CTD PMID:23835644 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO ginsenoside Re binds to and affects the activity of ESR1 protein CTD PMID:16985185 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression EXP ginsenoside Re results in increased expression of FABP4 mRNA CTD PMID:23545455 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fas Fas cell surface death receptor decreases expression
multiple interactions
ISO
EXP
ginsenoside Re results in decreased expression of FAS mRNA
ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of FAS mRNA]
CTD PMID:21971952 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO ginsenoside Re results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO ginsenoside Re results in decreased expression of G6PC1 mRNA CTD PMID:21971952 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions EXP ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA] CTD PMID:21971952 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP ginsenoside Re affects the reaction [GPX1 protein affects the expression of AIF1 protein]; ginsenoside Re affects the reaction [GPX1 protein affects the expression of and affects the localization of RELA protein]; ginsenoside Re affects the reaction [GPX1 protein affects the expression of PTAFR protein]; ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK1 protein]; ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK3 protein]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]] CTD PMID:29037473 PMID:36682417 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation EXP ginsenoside Re results in increased phosphorylation of GSK3B protein CTD PMID:17885204 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) increases expression EXP ginsenoside Re results in increased expression of HSPD1 protein CTD PMID:23144451 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Ifng interferon gamma decreases expression ISO ginsenoside Re results in decreased expression of IFNG protein CTD PMID:20230918 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions EXP ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:22849695 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; ginsenoside Re metabolite inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] CTD PMID:16557482 PMID:22494059 PMID:22849695 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP ginsenoside Re inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:17885204 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions ISO ginsenoside Re inhibits the reaction [Dietary Fats inhibits the reaction [INS1 protein results in increased localization of SLC2A4 protein]] CTD PMID:22571876 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions EXP ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased degradation of IRAK1 protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRAK1 protein] CTD PMID:22849695 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 multiple interactions EXP ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased degradation of IRAK4 protein] CTD PMID:22849695 NCBI chr15:94,441,495...94,466,198
Ensembl chr15:94,441,524...94,479,696
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 decreases expression ISO ginsenoside Re results in decreased expression of IRGM protein CTD PMID:20230918 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
increases expression
increases phosphorylation
EXP ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of IRS1 protein]
ginsenoside Re results in increased expression of IRS1 mRNA
ginsenoside Re results in increased phosphorylation of IRS1 protein
CTD PMID:17885204 PMID:23545455 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 increases expression ISO ginsenoside Re results in increased expression of KCNE1 CTD PMID:24615935 NCBI chr16:92,142,889...92,156,356
Ensembl chr16:92,142,870...92,156,356
JBrowse link
G Lpl lipoprotein lipase increases secretion EXP ginsenoside Re results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrpprc leucine-rich PPR-motif containing increases expression EXP ginsenoside Re results in increased expression of LRPPRC protein CTD PMID:23144451 NCBI chr17:85,012,675...85,098,214
Ensembl chr17:85,012,675...85,098,217
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP ginsenoside Re results in increased expression of MAP2 mRNA; ginsenoside Re results in increased expression of MAP2 protein CTD PMID:24599032 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
EXP ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK1 protein]; ginsenoside Re results in increased phosphorylation of and results in increased activity of MAPK1 protein
ginsenoside Re results in increased phosphorylation of MAPK1 protein
CTD PMID:24599032 PMID:36682417 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
EXP ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK3 protein]; ginsenoside Re results in increased phosphorylation of and results in increased activity of MAPK3 protein
ginsenoside Re results in increased phosphorylation of MAPK3 protein
CTD PMID:24599032 PMID:36682417 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22849695 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory affects phosphorylation ISO ginsenoside Re affects the phosphorylation of MYL9 protein CTD PMID:24658813 NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578
JBrowse link
G Mylk myosin, light polypeptide kinase affects expression ISO ginsenoside Re affects the expression of MYLK mRNA; ginsenoside Re affects the expression of MYLK protein CTD PMID:24658813 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions EXP ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [Phencyclidine affects the localization of NCF1 protein] CTD PMID:29037473 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP
ISO
ginsenoside Re inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] CTD PMID:17885204 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Ngf nerve growth factor increases expression EXP ginsenoside Re results in increased expression of NGF mRNA CTD PMID:24599032 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) increases expression EXP ginsenoside Re results in increased expression of NGFR mRNA; ginsenoside Re results in increased expression of NGFR protein CTD PMID:24599032 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression
multiple interactions
EXP ginsenoside Re results in decreased expression of NOS2 protein
ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:15621629 PMID:23102375 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions
increases phosphorylation
ISO 2-aminoethoxydiphenyl borate inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]; Mifepristone inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein] CTD PMID:17490654 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO ginsenoside Re results in increased expression of NR0B2 mRNA CTD PMID:21971952 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases activity
ISO [ginsenoside Re results in increased activity of NR3C1 protein] which results in increased abundance of Nitric Oxide CTD PMID:17490654 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Ocln occludin multiple interactions EXP ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein] CTD PMID:22849695 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:25523949 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions
decreases expression
EXP
ISO
ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]
ginsenoside Re results in decreased expression of PCK1 mRNA
CTD PMID:21971952 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pdyn prodynorphin multiple interactions EXP 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of PDYN mRNA]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]] CTD PMID:29467000 NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO ginsenoside Re binds to and affects the activity of PGR protein
ginsenoside Re results in increased expression of PGR protein
CTD PMID:16204943 PMID:16985185 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression EXP ginsenoside Re results in increased expression of PPARG mRNA CTD PMID:23545455 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit increases phosphorylation
multiple interactions
ISO
EXP
ginsenoside Re results in increased phosphorylation of PRKAA1 protein
ginsenoside Re inhibits the reaction [Dietary Fats results in decreased phosphorylation of PRKAA1 protein]
CTD PMID:21971952 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases response to substance
EXP
ISO
3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of and results in increased phosphorylation of PRKCD protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of and results in increased phosphorylation of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]
ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein]
PRKCD results in increased susceptibility to ginsenoside Re
CTD PMID:24430743 PMID:25523949 PMID:37308051 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions
decreases expression
EXP ginsenoside Re affects the reaction [GPX1 protein affects the expression of PTAFR protein]
ginsenoside Re results in decreased expression of PTAFR protein
CTD PMID:36682417 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; ginsenoside Re metabolite inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] CTD PMID:16557482 PMID:23102375 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP ginsenoside Re affects the reaction [GPX1 protein affects the expression of and affects the localization of RELA protein]; ginsenoside Re results in decreased expression of and affects the localization of RELA protein CTD PMID:36682417 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 increases phosphorylation EXP ginsenoside Re results in increased phosphorylation of RPS6KB1 protein CTD PMID:17885204 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions EXP ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of SCD1 mRNA] CTD PMID:21971952 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 decreases expression ISO ginsenoside Re results in decreased expression of SCD mRNA CTD PMID:21971952 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
JBrowse link
G Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 increases expression EXP ginsenoside Re results in increased expression of SLC18A3 mRNA CTD PMID:24599032 NCBI chr14:32,184,394...32,186,807
Ensembl chr14:32,184,395...32,186,807
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 multiple interactions
increases localization
ISO
EXP
ginsenoside Re inhibits the reaction [Dietary Fats inhibits the reaction [INS1 protein results in increased localization of SLC2A4 protein]]
ginsenoside Re results in increased localization of SLC2A4 protein
CTD PMID:17885204 PMID:22571876 PMID:23545455 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
JBrowse link
G Slc5a7 solute carrier family 5 (choline transporter), member 7 increases expression EXP ginsenoside Re results in increased expression of SLC5A7 mRNA CTD PMID:24599032 NCBI chr17:54,580,618...54,606,071
Ensembl chr17:54,580,618...54,606,062
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions ISO SLCO1B3 protein binds to and results in increased transport of ginsenoside Re
SLCO1B2 protein binds to and results in increased transport of ginsenoside Re
CTD PMID:25297453 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP ginsenoside Re inhibits the reaction [TNF protein results in increased expression of SOCS3 mRNA] CTD PMID:17885204 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
decreases activity
EXP ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]
ginsenoside Re results in decreased activity of SOD1 protein
CTD PMID:24430743 PMID:29037473 PMID:36682417 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions EXP ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased activity of SOD2 protein]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]] CTD PMID:29037473 PMID:37308051 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
decreases expression
EXP
ISO
ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]
ginsenoside Re results in decreased expression of SREBF1 mRNA
CTD PMID:21971952 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation ISO ginsenoside Re results in increased phosphorylation of STK11 protein CTD PMID:21971952 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
JBrowse link
G Tac1 tachykinin 1 multiple interactions EXP ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]] CTD PMID:29467000 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 increases phosphorylation EXP ginsenoside Re results in increased phosphorylation of TBC1D4 protein CTD PMID:17885204 NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO ginsenoside Re results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO
EXP
ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]
CTD PMID:25523949 PMID:29467000 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein] CTD PMID:22849695 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP ginsenoside Re inhibits the reaction [Lipopolysaccharides binds to TLR4 protein] CTD PMID:22849695 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; ginsenoside Re inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; ginsenoside Re inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; ginsenoside Re inhibits the reaction [TNF protein results in increased expression of SOCS3 mRNA]; ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein]; ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of IRS1 protein]; ginsenoside Re metabolite inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; ginsenoside Re results in decreased expression of and results in decreased secretion of TNF protein CTD PMID:16557482 PMID:17885204 PMID:22494059 PMID:22849695 PMID:23545455 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
ginsenoside Rf term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A-I multiple interactions
decreases expression
EXP ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 mRNA]; ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 protein]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 mRNA]]
ginsenoside Rf results in decreased expression of APOA1 protein
CTD PMID:16297877 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoc3 apolipoprotein C-III multiple interactions
decreases expression
increases expression
EXP ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 mRNA]; ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 protein]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 mRNA]]; PPARA protein affects the reaction [ginsenoside Rf results in increased expression of APOC3 mRNA]
ginsenoside Rf results in decreased expression of APOC3 protein
CTD PMID:16297877 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 affects activity ISO ginsenoside Rf affects the activity of KCNH2 protein CTD PMID:15842772 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases expression
EXP ginsenoside Rf binds to and results in decreased activity of PPARA protein; ginsenoside Rf inhibits the reaction [pirinixic acid results in increased activity of PPARA protein]; ginsenoside Rf inhibits the reaction [pirinixic acid results in increased expression of PPARA mRNA]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 mRNA]]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 mRNA]]; PPARA protein affects the reaction [ginsenoside Rf results in increased expression of APOC3 mRNA]
ginsenoside Rf results in decreased expression of PPARA mRNA
CTD PMID:16297877 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
ginsenoside Rg1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 increases transport
multiple interactions
ISO
EXP
ABCB11 protein results in increased transport of ginsenoside Rg1
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCB11 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCB11 protein]
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCB11 protein]
CTD PMID:25297453 PMID:29964319 PMID:32198087 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases transport ISO ABCC1 protein results in increased transport of ginsenoside Rg1 CTD PMID:25297453 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases transport
multiple interactions
increases expression
ISO
EXP
ABCC2 protein results in increased transport of ginsenoside Rg1
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]
ginsenoside Rg1 results in increased expression of ABCC2 protein
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein]; Tretinoin inhibits the reaction [ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein]]
CTD PMID:25297453 PMID:29964319 PMID:32198087 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 increases expression
multiple interactions
EXP ginsenoside Rg1 results in increased expression of ABCC3 protein
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC3 protein]; Tretinoin inhibits the reaction [ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC3 protein]]
CTD PMID:29964319 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 increases expression
multiple interactions
EXP ginsenoside Rg1 results in increased expression of ABCC4 protein
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC4 protein]
CTD PMID:29964319 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases transport ISO ABCG2 protein results in increased transport of ginsenoside Rg1 CTD PMID:25297453 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Ache acetylcholinesterase decreases activity EXP ginsenoside Rg1 results in decreased activity of ACHE protein CTD PMID:20564503 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Adam10 a disintegrin and metallopeptidase domain 10 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in decreased expression of ADAM10 mRNA] CTD PMID:22484447 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions EXP
ISO
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in decreased phosphorylation of AKT1 protein]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of AKT1 mRNA]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]
ginsenoside Rg1 inhibits the reaction [Doxorubicin results in increased expression of AKT1 mRNA]
CTD PMID:33331133 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of APAF1 mRNA] CTD PMID:34783124 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in decreased expression of ADAM10 mRNA]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of APP mRNA]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of APP protein alternative form]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of APP protein]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of BACE1 mRNA]; ginsenoside Rg1 results in decreased susceptibility to [APP protein alternative form co-treated with Dexamethasone] CTD PMID:22484447 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of ATF6 protein] CTD PMID:30918470 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions ISO ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of ATM mRNA] CTD PMID:34783124 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of BACE1 mRNA] CTD PMID:22484447 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]; ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]; Mifepristone inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]; SH-6 compound inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]] CTD PMID:17123556 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
EXP
ISO
ginsenoside Rg1 results in increased expression of BAX protein
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]
ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]
CTD PMID:28371286 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
EXP
ISO
ginsenoside Rg1 results in decreased expression of BCL2 protein
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2 protein]
CTD PMID:26593335 PMID:28371286 PMID:34859534 PMID:36811218 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CASP3 mRNA]
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP3 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]
ginsenoside Rg1 results in increased activity of CASP3 protein
CTD PMID:24386346 PMID:28371286 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
EXP
ISO
ginsenoside Rg1 results in increased activity of CASP9 protein
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP9 protein]
ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CASP9 mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP9 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP9 protein]
CTD PMID:28371286 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:29964319 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CCNE1 protein] CTD PMID:15606011 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of CDH1 mRNA]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of CDH1 protein] CTD PMID:33331133 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDK2 protein] CTD PMID:15606011 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions ISO ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDKN1A protein]; ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:15606011 PMID:34783124 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of CREB1 protein] CTD PMID:33331133 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP2B10 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP2B10 protein] CTD PMID:32198087 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:29964319 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of DDIT3 protein] CTD PMID:30918470 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of ERN1 protein] CTD PMID:30918470 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO ginsenoside Rg1 results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in increased expression of FSHB protein] CTD PMID:33331133 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of FSHR protein] CTD PMID:33331133 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
EXP ginsenoside Rg1 results in increased expression of GCLC mRNA
ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]]
CTD PMID:29964319 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression
multiple interactions
EXP ginsenoside Rg1 results in increased expression of GCLM protein
ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein]
CTD PMID:29964319 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of GJA1 mRNA]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of GJA1 protein] CTD PMID:33331133 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in increased expression of GLUD1 protein] CTD PMID:26593335 NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:29964319 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein] CTD PMID:34859534 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of H2AX mRNA] CTD PMID:34783124 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 mRNA; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 protein; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]
ginsenoside Rg1 results in increased expression of HMOX1 mRNA; ginsenoside Rg1 results in increased expression of HMOX1 protein
CTD PMID:25422538 PMID:29964319 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of HSPA5 protein] CTD PMID:30918470 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Ifng interferon gamma multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IFNG protein] CTD PMID:32198087 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of IL1B protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B]
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B protein]
CTD PMID:22214447 PMID:29964319 PMID:32198087 PMID:36811218 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of IL6 protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:17655881 PMID:29964319 PMID:30918470 PMID:36811218 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inha inhibin alpha multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of INHA protein] CTD PMID:33331133 NCBI chr 1:75,483,872...75,487,010
Ensembl chr 1:75,483,721...75,487,010
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 affects activity ISO ginsenoside Rg1 affects the activity of KCNH2 protein CTD PMID:15842772 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] CTD PMID:29964319 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Lhb luteinizing hormone beta multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of LHB protein] CTD PMID:33331133 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Lpl lipoprotein lipase increases secretion EXP ginsenoside Rg1 results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP ginsenoside Rg1 results in increased expression of MAP2 mRNA CTD PMID:24599032 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
affects phosphorylation
EXP PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK1 protein] CTD PMID:22214447 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 affects phosphorylation
multiple interactions
EXP ginsenoside Rg1 affects the phosphorylation of MAPK3 protein
PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK3 protein]
CTD PMID:22214447 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:24386346 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Met met proto-oncogene multiple interactions
increases expression
ISO Mifepristone inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein]; MIR23A mRNA inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein] CTD PMID:26115870 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 mRNA]; ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 protein] CTD PMID:26593335 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
JBrowse link
G Mir23a microRNA 23a decreases expression
multiple interactions
ISO ginsenoside Rg1 results in decreased expression of MIR23A mRNA
Mifepristone inhibits the reaction [ginsenoside Rg1 results in decreased expression of MIR23A mRNA]; MIR23A mRNA inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein]
CTD PMID:26115870 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO ginsenoside Rg1 results in increased expression of MMP2 protein CTD PMID:23738715 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO ginsenoside Rg1 results in increased expression of MMP9 protein CTD PMID:23738715 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO
EXP
ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in decreased activity of [MTOR protein binds to RAPTOR protein]]; ginsenoside Rg1 results in increased activity of [MTOR protein binds to RAPTOR protein]
ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of MTOR protein]
CTD PMID:24386346 PMID:33331133 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
affects localization
increases expression
ISO
EXP
[ginsenoside Rg1 co-treated with ginsenoside 20S-protopanaxatriol] results in increased expression of NFE2L2 protein
ginsenoside Rg1 affects the localization of NFE2L2 protein
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] affects the localization of NFE2L2 protein; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]]; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]]
ginsenoside Rg1 results in increased expression of NFE2L2 mRNA
CTD PMID:22780686 PMID:25422538 PMID:29964319 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha affects phosphorylation
multiple interactions
EXP ginsenoside Rg1 affects the phosphorylation of NFKBIA protein
PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of NFKBIA protein]
CTD PMID:22214447 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2] CTD PMID:22214447 PMID:29964319 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]]; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]] CTD PMID:29964319 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein] CTD PMID:32198087 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Pgr progesterone receptor increases expression ISO ginsenoside Rg1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of PIK3CA mRNA] CTD PMID:33331133 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK1 protein]; PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK3 protein]; PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of NFKBIA protein] CTD PMID:22214447 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions ISO ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of PRKAA1 protein] CTD PMID:24386346 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in increased expression of PTEN protein] CTD PMID:33331133 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2] CTD PMID:22214447 PMID:29964319 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rad51 RAD51 recombinase multiple interactions ISO ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of RAD51 mRNA] CTD PMID:34783124 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
JBrowse link
G Rps6 ribosomal protein S6 increases phosphorylation ISO ginsenoside Rg1 results in increased phosphorylation of RPS6 protein CTD PMID:24386346 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in decreased activity of [MTOR protein binds to RAPTOR protein]]; ginsenoside Rg1 results in increased activity of [MTOR protein binds to RAPTOR protein] CTD PMID:24386346 NCBI chr11:119,493,731...119,790,417
Ensembl chr11:119,493,731...119,790,402
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of SIRT1 protein] CTD PMID:30918470 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein] CTD PMID:32198087 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions ISO SLCO1B2 protein binds to and results in increased transport of ginsenoside Rg1
SLCO1B3 protein binds to and results in increased transport of ginsenoside Rg1
CTD PMID:25297453 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SULT2A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SULT2A1 protein] CTD PMID:32198087 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO ginsenoside Rg1 results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]
CTD PMID:22214447 PMID:29964319 PMID:30918470 PMID:32198087 PMID:36811218 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of TP53 mRNA] CTD PMID:34783124 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein] CTD PMID:32198087 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 multiple interactions ISO ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of XRCC1 mRNA] CTD PMID:34783124 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865
JBrowse link
ginsenoside Rg2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression ISO ginsenoside Rg2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein] CTD PMID:28756148 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of CASP3 protein]]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of and results in increased cleavage of CASP3 protein]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased expression of BAX protein] CTD PMID:28756148 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased expression of BAX protein] CTD PMID:28756148 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein] CTD PMID:28756148 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Becn2 beclin 2 multiple interactions ISO
EXP
ginsenoside Rg2 inhibits the reaction [BECN2 protein binds to GPRASP1 protein] CTD PMID:27305347 NCBI chr 1:175,747,895...175,749,791
Ensembl chr 1:175,747,895...175,749,791
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of CASP3 protein]]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of and results in increased cleavage of CASP3 protein] CTD PMID:28756148 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 multiple interactions ISO [ginsenoside Rg2 results in increased activity of NR0B2 protein] which results in decreased activity of CRTC2 protein CTD PMID:22062806 NCBI chr 3:90,161,475...90,171,432
Ensembl chr 3:90,161,470...90,171,432
JBrowse link
G G6pc3 glucose 6 phosphatase, catalytic, 3 decreases expression
multiple interactions
ISO ginsenoside Rg2 results in decreased expression of G6PC3 mRNA
dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of G6PC3 mRNA]
CTD PMID:22062806 NCBI chr11:102,080,525...102,084,907
Ensembl chr11:102,080,446...102,084,907
JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 multiple interactions ISO
EXP
ginsenoside Rg2 inhibits the reaction [BECN2 protein binds to GPRASP1 protein] CTD PMID:27305347 NCBI chr  X:134,643,441...134,704,217
Ensembl chr  X:134,643,482...134,704,223
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
ISO ginsenoside Rg2 results in increased phosphorylation of GSK3B protein
[[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose; dorsomorphin inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of GSK3B protein]
CTD PMID:22062806 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form
bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]
CTD PMID:27305347 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
increases activity
ISO [[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose; [ginsenoside Rg2 results in increased activity of NR0B2 protein] which results in decreased activity of CRTC2 protein CTD PMID:22062806 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions
decreases expression
ISO dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of PCK1 mRNA] CTD PMID:22062806 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions
decreases expression
ISO dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of PPARGC1A mRNA] CTD PMID:22062806 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression
ISO
EXP
bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein] CTD PMID:27305347 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation
multiple interactions
ISO ginsenoside Rg2 results in increased phosphorylation of STK11 protein
dorsomorphin inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of STK11 protein]
CTD PMID:22062806 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
JBrowse link
glycitin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO glycitin inhibits the reaction [APP protein binds to APP protein] CTD PMID:17323972 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 6:72,183,158...72,212,765
Ensembl chr 6:72,183,161...72,212,561
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 7:127,503,245...127,508,836
Ensembl chr 7:127,503,254...127,509,393
JBrowse link
G Bpgm 2,3-bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 7:13,119,885...13,142,812
Ensembl chr 7:13,132,057...13,142,812
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr 1:160,029,171...160,040,391
Ensembl chr 1:160,029,937...160,040,445
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr16:44,586,141...44,615,341
Ensembl chr16:44,586,099...44,615,341
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr 5:123,390,196...123,465,547
Ensembl chr 5:123,390,165...123,465,547
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 2:70,948,398...70,973,270
Ensembl chr 2:70,948,267...70,973,270
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 3:106,389,745...106,410,346
Ensembl chr 3:106,389,721...106,410,346
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
JBrowse link
G Dpp9 dipeptidylpeptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr17:56,493,674...56,525,927
Ensembl chr17:56,493,807...56,525,905
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 7:133,239,422...133,274,710
Ensembl chr 7:133,239,272...133,274,700
JBrowse link
G Efhd1 EF hand domain containing 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 1:87,192,075...87,238,563
Ensembl chr 1:87,192,085...87,238,561
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr11:102,327,807...102,338,551
Ensembl chr11:102,327,807...102,338,508
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 2:172,187,444...172,197,669
Ensembl chr 2:172,187,485...172,197,669
JBrowse link
G Fam241b family with sequence similarity 241, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr10:61,943,435...61,946,829
Ensembl chr10:61,943,434...61,979,699
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr10:93,871,862...93,981,201
Ensembl chr10:93,871,863...93,981,201
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr14:31,750,739...31,784,161
Ensembl chr14:31,750,946...31,784,154
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 3:146,205,591...146,211,298
Ensembl chr 3:146,205,562...146,211,327
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 7:27,222,686...27,230,605
Ensembl chr 7:27,222,692...27,230,600
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr 1:150,438,251...150,869,568
Ensembl chr 1:150,438,275...150,869,186
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Il6ra interleukin 6 receptor, alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 3:87,837,602...87,847,994
Ensembl chr 3:87,837,621...87,847,993
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535
JBrowse link
G Kitl kit ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 2:118,644,470...118,667,691
Ensembl chr 2:118,644,484...118,684,438
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 4:134,468,865...134,495,342
Ensembl chr 4:134,468,865...134,495,335
JBrowse link
G Lmod1 leiomodin 1 (smooth muscle) multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr 1:135,252,551...135,295,803
Ensembl chr 1:135,252,545...135,295,803
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 5:31,771,295...31,779,988
Ensembl chr 5:31,754,279...31,821,728
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 3:96,069,287...96,079,034
Ensembl chr 3:96,069,321...96,079,034
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr19:37,887,484...38,032,025
Ensembl chr19:37,887,484...38,032,025
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Prpf40a pre-mRNA processing factor 40A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 2:53,024,714...53,081,450
Ensembl chr 2:53,024,716...53,081,714
JBrowse link
G Pspc1 paraspeckle protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr14:56,959,898...57,015,775
Ensembl chr14:56,958,167...57,015,773
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 9:110,551,132...110,576,213
Ensembl chr 9:110,551,153...110,576,213
JBrowse link
G Rassf5 Ras association (RalGDS/AF-6) domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr 1:131,104,147...131,172,915
Ensembl chr 1:131,104,147...131,172,995
JBrowse link
G Rgs22 regulator of G-protein signalling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr15:35,960,664...36,140,718
Ensembl chr15:36,009,625...36,140,546
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr13:51,562,654...51,576,833
Ensembl chr13:51,562,675...51,576,833
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr 5:113,955,859...113,970,576
Ensembl chr 5:113,956,597...113,970,705
JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 4:59,805,137...59,904,740
Ensembl chr 4:59,805,840...59,904,737
JBrowse link
G Ssc5d scavenger receptor cysteine rich family, 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 7:4,928,820...4,947,827
Ensembl chr 7:4,928,784...4,947,825
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr 5:135,776,074...135,807,277
Ensembl chr 5:135,776,074...135,807,239
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr12:101,611,705...101,685,178
Ensembl chr12:101,611,702...101,684,782
JBrowse link
G Trp53i11 transformation related protein 53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 2:93,017,694...93,032,102
Ensembl chr 2:93,017,893...93,032,104
JBrowse link
G Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 1:9,788,847...9,818,607
Ensembl chr 1:9,788,847...9,818,607
JBrowse link
gypenoside LXXV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
EXP gypenoside LXXV results in increased phosphorylation of AKT1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in increased phosphorylation of AKT1 protein]
CTD PMID:35192202 PMID:36325883 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 protein] CTD PMID:35192202 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
EXP gypenoside LXXV results in increased expression of and results in increased secretion of CTGF protein
gypenoside LXXV results in increased expression of CTGF mRNA
CTD PMID:31018484 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL1B protein] CTD PMID:33050067 PMID:35192202 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL6 protein] CTD PMID:35192202 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases phosphorylation
EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in decreased expression of and results in decreased phosphorylation of IRS1 protein]; gypenoside LXXV results in decreased expression of and results in decreased phosphorylation of IRS1 protein
gypenoside LXXV results in decreased phosphorylation of IRS1 protein
CTD PMID:35192202 PMID:36325883 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Lepr leptin receptor multiple interactions EXP gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL1B protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL6 protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of TNF protein] CTD PMID:35192202 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions EXP gypenoside LXXV binds to and affects the localization of NR3C2 protein CTD PMID:31018484 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression
EXP
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in increased expression of PPARG protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV binds to and results in increased activity of PPARG protein]; gypenoside LXXV binds to and results in increased activity of PPARG protein
CTD PMID:35192202 PMID:36325883 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP gypenoside LXXV results in decreased expression of and results in decreased phosphorylation of RELA protein CTD PMID:33050067 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 affects localization
increases expression
multiple interactions
EXP gypenoside LXXV affects the localization of SLC2A4 protein
gypenoside LXXV results in increased expression of SLC2A4 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gypenoside LXXV affects the localization of SLC2A4 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV affects the localization of SLC2A4 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in increased expression of SLC2A4 protein]
CTD PMID:35192202 PMID:36325883 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP gypenoside LXXV results in decreased expression of TGFB1 protein CTD PMID:33050067 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of TNF protein]; gypenoside LXXV inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:33050067 PMID:35192202 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
hydroquinone O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2200002D01Rik RIKEN cDNA 2200002D01 gene decreases expression ISO Arbutin results in decreased expression of C19ORF33 mRNA CTD PMID:17103032 NCBI chr 7:28,946,946...28,947,892
Ensembl chr 7:28,945,986...28,947,891
JBrowse link
G Abca13 ATP-binding cassette, sub-family A member 13 decreases expression ISO Arbutin results in decreased expression of ABCA13 mRNA CTD PMID:17103032 NCBI chr11:9,141,942...9,634,871
Ensembl chr11:9,141,942...9,634,259
JBrowse link
G Acmsd amino carboxymuconate semialdehyde decarboxylase decreases expression ISO Arbutin results in decreased expression of ACMSD mRNA CTD PMID:17103032 NCBI chr 1:127,657,149...127,695,723
Ensembl chr 1:127,657,150...127,695,715
JBrowse link
G Acvrl1 activin A receptor, type II-like 1 decreases expression ISO Arbutin results in decreased expression of ACVRL1 mRNA CTD PMID:17103032 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO Arbutin results in decreased expression of ADAM19 mRNA CTD PMID:17103032 NCBI chr11:45,945,329...46,038,174
Ensembl chr11:45,946,819...46,038,170
JBrowse link
G Adam20 a disintegrin and metallopeptidase domain 20 decreases expression ISO Arbutin results in decreased expression of ADAM20 mRNA CTD PMID:17103032 NCBI chr 8:41,246,310...41,250,379
Ensembl chr 8:41,246,310...41,250,340
JBrowse link
G Adam7 a disintegrin and metallopeptidase domain 7 increases expression ISO Arbutin results in increased expression of ADAM7 mRNA CTD PMID:17103032 NCBI chr14:68,734,785...68,771,138
Ensembl chr14:68,734,785...68,771,190
JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1 motif 3 decreases expression ISO Arbutin results in decreased expression of ADAMTS3 mRNA CTD PMID:17103032 NCBI chr 5:89,821,700...90,031,521
Ensembl chr 5:89,824,946...90,031,193
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9 decreases expression ISO Arbutin results in decreased expression of ADAMTS9 mRNA CTD PMID:17103032 NCBI chr 6:92,749,680...92,921,431
Ensembl chr 6:92,749,680...92,920,473
JBrowse link
G Adrb3 adrenergic receptor, beta 3 decreases expression ISO Arbutin results in decreased expression of ADRB3 mRNA CTD PMID:17103032 NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644
JBrowse link
G Aebp2 AE binding protein 2 increases expression ISO Arbutin results in increased expression of AEBP2 mRNA CTD PMID:17103032 NCBI chr 6:140,567,480...140,624,198
Ensembl chr 6:140,546,644...140,713,010
JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO Arbutin results in decreased expression of AFAP1 mRNA CTD PMID:17103032 NCBI chr 5:36,050,713...36,161,267
Ensembl chr 5:36,050,663...36,161,267
JBrowse link
G Agbl4 ATP/GTP binding protein-like 4 decreases expression ISO Arbutin results in decreased expression of AGBL4 mRNA CTD PMID:17103032 NCBI chr 4:110,254,823...111,521,521
Ensembl chr 4:110,254,858...111,521,521
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Arbutin results in decreased expression of AGPAT3 mRNA CTD PMID:17103032 NCBI chr10:78,105,008...78,188,335
Ensembl chr10:78,105,012...78,188,323
JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO Arbutin results in decreased expression of AHNAK mRNA CTD PMID:17103032 NCBI chr19:8,966,640...9,054,299
Ensembl chr19:8,966,648...9,054,278
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases expression ISO Arbutin results in decreased expression of AKT1 mRNA CTD PMID:17103032 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of Arbutin CTD PMID:8831264 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Amtn amelotin decreases expression ISO Arbutin results in decreased expression of AMTN mRNA CTD PMID:17103032 NCBI chr 5:88,523,967...88,533,775
Ensembl chr 5:88,523,967...88,533,775
JBrowse link
G Ankrd17 ankyrin repeat domain 17 increases expression ISO Arbutin results in increased expression of ANKRD17 mRNA CTD PMID:17103032 NCBI chr 5:90,375,025...90,517,133
Ensembl chr 5:90,375,025...90,514,436
JBrowse link
G Ankrd23 ankyrin repeat domain 23 increases expression ISO Arbutin results in increased expression of ANKRD23 mRNA CTD PMID:17103032 NCBI chr 1:36,569,269...36,578,380
Ensembl chr 1:36,569,269...36,575,964
Ensembl chr 1:36,569,269...36,575,964
JBrowse link
G Ap1s1 adaptor protein complex AP-1, sigma 1 decreases expression ISO Arbutin results in decreased expression of AP1S1 mRNA CTD PMID:17103032 NCBI chr 5:137,063,852...137,074,917
Ensembl chr 5:137,063,847...137,074,989
JBrowse link
G Apom apolipoprotein M increases expression ISO Arbutin results in increased expression of APOM mRNA CTD PMID:17103032 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026
JBrowse link
G Aptx aprataxin decreases expression ISO Arbutin results in decreased expression of APTX mRNA CTD PMID:17103032 NCBI chr 4:40,682,078...40,703,206
Ensembl chr 4:40,682,382...40,703,194
JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 decreases expression ISO Arbutin results in decreased expression of ARFIP2 mRNA CTD PMID:17103032 NCBI chr 7:105,283,408...105,289,623
Ensembl chr 7:105,283,410...105,289,623
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Arbutin results in decreased expression of ARHGEF2 mRNA CTD PMID:17103032 NCBI chr 3:88,500,427...88,556,839
Ensembl chr 3:88,513,273...88,555,359
JBrowse link
G Arl2 ADP-ribosylation factor-like 2 decreases expression ISO Arbutin results in decreased expression of ARL2 mRNA CTD PMID:17103032 NCBI chr19:6,184,419...6,191,167
Ensembl chr19:6,184,404...6,191,578
JBrowse link
G Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 increases expression ISO Arbutin results in increased expression of ARL6IP1 mRNA CTD PMID:17103032 NCBI chr 7:117,718,113...117,728,848
Ensembl chr 7:117,718,114...117,728,885
JBrowse link
G Arx aristaless related homeobox decreases expression ISO Arbutin results in decreased expression of ARX mRNA CTD PMID:17103032 NCBI chr  X:92,330,113...92,341,963
Ensembl chr  X:92,330,051...92,341,963
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain1 increases expression ISO Arbutin results in increased expression of ASAP1 mRNA CTD PMID:17103032 NCBI chr15:63,958,704...64,254,922
Ensembl chr15:63,958,706...64,254,768
JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 decreases expression ISO Arbutin results in decreased expression of ASAP3 mRNA CTD PMID:17103032 NCBI chr 4:135,933,662...135,973,888
Ensembl chr 4:135,933,676...135,972,527
JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO Arbutin results in decreased expression of ATF6B mRNA CTD PMID:17103032 NCBI chr17:34,866,120...34,874,048
Ensembl chr17:34,866,120...34,874,048
JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 decreases expression ISO Arbutin results in decreased expression of B4GALNT4 mRNA CTD PMID:17103032 NCBI chr 7:140,640,891...140,652,313
Ensembl chr 7:140,641,017...140,652,313
JBrowse link
G Bag5 BCL2-associated athanogene 5 decreases expression ISO Arbutin results in decreased expression of BAG5 mRNA CTD PMID:17103032 NCBI chr12:111,675,922...111,679,690
Ensembl chr12:111,675,922...111,679,691
JBrowse link
G Bcas2 BCAS2 pre-mRNA processing factor increases expression ISO Arbutin results in increased expression of BCAS2 mRNA CTD PMID:17103032 NCBI chr 3:103,078,971...103,086,479
Ensembl chr 3:103,078,971...103,086,482
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases expression ISO Arbutin results in decreased expression of BCKDK mRNA CTD PMID:17103032 NCBI chr 7:127,503,245...127,508,836
Ensembl chr 7:127,503,254...127,509,393
JBrowse link
G Bmpr1b bone morphogenetic protein receptor, type 1B decreases expression ISO Arbutin results in decreased expression of BMPR1B mRNA CTD PMID:17103032 NCBI chr 3:141,540,230...141,875,335
Ensembl chr 3:141,542,897...141,875,186
JBrowse link
G Bnip2 BCL2/adenovirus E1B interacting protein 2 increases expression ISO Arbutin results in increased expression of BNIP2 mRNA CTD PMID:17103032 NCBI chr 9:69,896,660...69,918,941
Ensembl chr 9:69,896,748...69,915,599
JBrowse link
G Brsk1 BR serine/threonine kinase 1 decreases expression ISO Arbutin results in decreased expression of BRSK1 mRNA CTD PMID:17103032 NCBI chr 7:4,693,635...4,718,996
Ensembl chr 7:4,693,603...4,718,996
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Arbutin results in decreased expression of BST2 mRNA CTD PMID:17103032 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100
JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide decreases expression ISO Arbutin results in decreased expression of C1QB mRNA CTD PMID:17103032 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
JBrowse link
G Cacng7 calcium channel, voltage-dependent, gamma subunit 7 decreases expression ISO Arbutin results in decreased expression of CACNG7 mRNA CTD PMID:17103032 NCBI chr 7:3,381,341...3,416,737
Ensembl chr 7:3,381,471...3,416,737
JBrowse link
G Capns2 calpain, small subunit 2 increases expression ISO Arbutin results in increased expression of CAPNS2 mRNA CTD PMID:17103032 NCBI chr 8:93,628,023...93,629,037
Ensembl chr 8:93,628,035...93,629,039
JBrowse link
G Casp8 caspase 8 decreases expression ISO Arbutin results in decreased expression of CASP8 mRNA CTD PMID:17103032 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase multiple interactions ISO Arbutin inhibits the reaction [potassium bromate results in decreased activity of CAT protein] CTD PMID:36284482 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbx6 chromobox 6 decreases expression ISO Arbutin results in decreased expression of CBX6 mRNA CTD PMID:17103032 NCBI chr15:79,708,099...79,718,534
Ensembl chr15:79,708,097...79,718,889
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Arbutin results in increased expression of CCAR1 mRNA CTD PMID:17103032 NCBI chr10:62,579,707...62,628,147
Ensembl chr10:62,579,707...62,628,065
JBrowse link
G Ccdc170 coiled-coil domain containing 170 decreases expression ISO Arbutin results in decreased expression of CCDC170 mRNA CTD PMID:17103032 NCBI chr10:4,432,312...4,514,498
Ensembl chr10:4,432,502...4,512,231
JBrowse link
G Ccdc28b coiled coil domain containing 28B decreases expression ISO Arbutin results in decreased expression of CCDC28B mRNA CTD PMID:17103032 NCBI chr 4:129,513,067...129,517,820
Ensembl chr 4:129,513,067...129,517,740
JBrowse link
G Ccnyl1 cyclin Y-like 1 increases expression ISO Arbutin results in increased expression of CCNYL1 mRNA CTD PMID:17103032 NCBI chr 1:64,729,963...64,764,805
Ensembl chr 1:64,729,614...64,764,803
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression ISO Arbutin results in increased expression of CCT8 mRNA CTD PMID:17103032 NCBI chr16:87,280,213...87,292,757
Ensembl chr16:87,280,214...87,292,761
JBrowse link
G Cd151 CD151 antigen decreases expression ISO Arbutin results in decreased expression of CD151 mRNA CTD PMID:17103032 NCBI chr 7:141,047,275...141,051,394
Ensembl chr 7:141,047,305...141,051,386
JBrowse link
G Cd160 CD160 antigen decreases expression ISO Arbutin results in decreased expression of CD160 mRNA CTD PMID:17103032 NCBI chr 3:96,706,079...96,736,667
Ensembl chr 3:96,706,079...96,736,667
JBrowse link
G Cd2bp2 CD2 cytoplasmic tail binding protein 2 decreases expression ISO Arbutin results in decreased expression of CD2BP2 mRNA CTD PMID:17103032 NCBI chr 7:126,790,832...126,795,249
Ensembl chr 7:126,790,832...126,795,222
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide decreases expression ISO Arbutin results in decreased expression of CD3G mRNA CTD PMID:17103032 NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
JBrowse link
G Cdin1 CDAN1 interacting nuclease 1 increases expression ISO Arbutin results in increased expression of CDIN1 mRNA CTD PMID:17103032 NCBI chr 2:115,411,388...115,609,263
Ensembl chr 2:115,412,197...115,609,249
JBrowse link
G Cdk16 cyclin dependent kinase 16 decreases expression ISO Arbutin results in decreased expression of CDK16 mRNA CTD PMID:17103032 NCBI chr  X:20,554,210...20,566,119
Ensembl chr  X:20,554,193...20,566,119
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO Arbutin results in decreased expression of CEACAM1 mRNA CTD PMID:17103032 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028
JBrowse link
G Cfap161 cilia and flagella associated protein 161 decreases expression ISO Arbutin results in decreased expression of CFAP161 mRNA CTD PMID:17103032 NCBI chr 7:83,424,820...83,447,528
Ensembl chr 7:83,423,309...83,444,088
JBrowse link
G Cfap70 cilia and flagella associated protein 70 decreases expression ISO Arbutin results in decreased expression of CFAP70 mRNA CTD PMID:17103032 NCBI chr14:20,444,258...20,502,332
Ensembl chr14:20,444,261...20,502,294
JBrowse link
G Clec4b1 C-type lectin domain family 4, member b1 decreases expression ISO Arbutin results in decreased expression of CLEC4C mRNA CTD PMID:17103032 NCBI chr 6:123,026,921...123,048,514
Ensembl chr 6:123,026,921...123,048,514
JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO Arbutin results in decreased expression of CNKSR2 mRNA CTD PMID:17103032 NCBI chr  X:156,604,426...156,827,454
Ensembl chr  X:156,604,432...156,826,290
JBrowse link
G Col17a1 collagen, type XVII, alpha 1 decreases expression ISO Arbutin results in decreased expression of COL17A1 mRNA CTD PMID:17103032 NCBI chr19:47,634,783...47,680,460
Ensembl chr19:47,634,783...47,680,533
JBrowse link
G Cpb1 carboxypeptidase B1 decreases expression ISO Arbutin results in decreased expression of CPB1 mRNA CTD PMID:17103032 NCBI chr 3:20,303,643...20,339,681
Ensembl chr 3:20,302,428...20,329,897
JBrowse link
G Cpe carboxypeptidase E increases expression ISO Arbutin results in increased expression of CPE mRNA CTD PMID:17103032 NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088
JBrowse link
G Cpne5 copine V increases expression ISO Arbutin results in increased expression of CPNE5 mRNA CTD PMID:17103032 NCBI chr17:29,375,495...29,456,764
Ensembl chr17:29,374,530...29,457,141
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Arbutin results in decreased expression of CYP17A1 mRNA; Arbutin results in decreased expression of CYP17A1 protein CTD PMID:37783241 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 increases expression ISO Arbutin results in increased expression of CYP2U1 mRNA CTD PMID:17103032 NCBI chr 3:131,084,140...131,097,806
Ensembl chr 3:131,082,090...131,096,876
JBrowse link
G Cyrib CYFIP related Rac1 interactor B increases expression ISO Arbutin results in increased expression of CYRIB mRNA CTD PMID:17103032 NCBI chr15:63,800,943...63,932,627
Ensembl chr15:63,800,946...63,932,327
JBrowse link
G Ddx46 DEAD box helicase 46 increases expression ISO Arbutin results in increased expression of DDX46 mRNA CTD PMID:17103032 NCBI chr13:55,782,790...55,829,080
Ensembl chr13:55,782,841...55,829,069
JBrowse link
G Diaph2 diaphanous related formin 2 decreases expression ISO Arbutin results in decreased expression of DIAPH2 mRNA CTD PMID:17103032 NCBI chr  X:128,650,409...129,366,583
Ensembl chr  X:128,650,491...129,366,583
JBrowse link
G Dlgap4 DLG associated protein 4 increases expression ISO Arbutin results in increased expression of DLGAP4 mRNA CTD PMID:17103032 NCBI chr 2:156,455,431...156,606,283
Ensembl chr 2:156,455,625...156,606,283
JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO Arbutin results in decreased expression of DLX1 mRNA CTD PMID:17103032 NCBI chr 2:71,358,457...71,364,325
Ensembl chr 2:71,358,457...71,364,325
JBrowse link
G Dmxl1 Dmx-like 1 decreases expression ISO Arbutin results in decreased expression of DMXL1 mRNA CTD PMID:17103032 NCBI chr18:49,965,657...50,098,540
Ensembl chr18:49,965,737...50,098,540
JBrowse link
G Dnah7b dynein, axonemal, heavy chain 7B decreases expression ISO Arbutin results in decreased expression of DNAH7 mRNA CTD PMID:17103032 NCBI chr 1:46,105,232...46,412,711
Ensembl chr 1:46,105,475...46,412,710
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 decreases expression ISO Arbutin results in decreased expression of DNAI3 mRNA CTD PMID:17103032 NCBI chr 3:145,746,281...145,813,855
Ensembl chr 3:145,746,281...145,813,885
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Arbutin results in increased expression of DNAJB9 mRNA CTD PMID:17103032 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
JBrowse link
G Dpp7 dipeptidylpeptidase 7 decreases expression ISO Arbutin results in decreased expression of DPP7 mRNA CTD PMID:17103032 NCBI chr 2:25,242,302...25,246,365
Ensembl chr 2:25,242,288...25,246,371
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Arbutin results in decreased expression of DPYSL2 mRNA CTD PMID:17103032 NCBI chr14:67,040,313...67,148,490
Ensembl chr14:67,040,313...67,106,137
JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression ISO Arbutin results in increased expression of ECE1 mRNA CTD PMID:17103032 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Arbutin results in increased expression of EEPD1 mRNA CTD PMID:17103032 NCBI chr 9:25,392,809...25,515,406
Ensembl chr 9:25,392,843...25,515,406
JBrowse link
G Efhc2 EF-hand domain (C-terminal) containing 2 decreases expression ISO Arbutin results in decreased expression of EFHC2 mRNA CTD PMID:17103032 NCBI chr  X:16,998,288...17,186,291
Ensembl chr  X:16,998,288...17,185,607
JBrowse link
G Efl1 elongation factor like GTPase 1 increases expression ISO Arbutin results in increased expression of EFL1 mRNA CTD PMID:17103032 NCBI chr 7:82,297,811...82,427,060
Ensembl chr 7:82,297,822...82,427,060
JBrowse link
G Efna3 ephrin A3 decreases expression ISO Arbutin results in decreased expression of EFNA3 mRNA CTD PMID:17103032 NCBI chr 3:89,221,200...89,231,359
Ensembl chr 3:89,221,206...89,230,272
JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO Arbutin results in decreased expression of EFS mRNA CTD PMID:17103032 NCBI chr14:55,154,087...55,164,222
Ensembl chr14:55,153,992...55,163,583
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 increases expression ISO Arbutin results in increased expression of EID1 mRNA CTD PMID:17103032 NCBI chr 2:125,515,020...125,517,563
Ensembl chr 2:125,515,015...125,516,705
JBrowse link
G Elane elastase, neutrophil expressed decreases expression ISO Arbutin results in decreased expression of ELANE mRNA CTD PMID:17103032 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049
JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Arbutin results in decreased expression of EMX2 mRNA CTD PMID:17103032 NCBI chr19:59,447,122...59,453,789
Ensembl chr19:59,446,804...59,453,789
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression ISO Arbutin results in decreased expression of ENPP1 mRNA CTD PMID:17103032 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO Arbutin results in increased expression of EPS8 mRNA CTD PMID:17103032 NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
JBrowse link
G Epx eosinophil peroxidase increases expression ISO Arbutin results in increased expression of EPX mRNA CTD PMID:17103032 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression ISO Arbutin results in increased expression of ERC1 mRNA CTD PMID:17103032 NCBI chr 6:119,547,757...119,830,985
Ensembl chr 6:119,547,757...119,825,128
JBrowse link
G Esr2 estrogen receptor 2 (beta) increases expression ISO
EXP
Arbutin results in increased expression of ESR2 protein CTD PMID:29360751 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Evi2b ecotropic viral integration site 2b decreases expression ISO Arbutin results in decreased expression of EVI2B mRNA CTD PMID:17103032 NCBI chr11:79,404,211...79,414,588
Ensembl chr11:79,405,882...79,414,588
JBrowse link
G Exd1 exonuclease 3'-5' domain containing 1 decreases expression ISO Arbutin results in decreased expression of EXD1 mRNA CTD PMID:17103032 NCBI chr 2:119,346,986...119,378,108
Ensembl chr 2:119,346,986...119,378,108
JBrowse link
G F13b coagulation factor XIII, beta subunit decreases expression ISO Arbutin results in decreased expression of F13B mRNA CTD PMID:17103032 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D decreases expression ISO Arbutin results in decreased expression of FAM3D mRNA CTD PMID:17103032 NCBI chr14:14,091,010...14,120,836
Ensembl chr14:14,091,019...14,120,836
JBrowse link
G Fancd2os Fancd2 opposite strand decreases expression ISO Arbutin results in decreased expression of FANCD2OS mRNA CTD PMID:17103032 NCBI chr 6:113,573,722...113,577,735
Ensembl chr 6:113,573,722...113,577,676
JBrowse link
G Fasl Fas ligand decreases expression ISO Arbutin results in decreased expression of FASLG mRNA CTD PMID:17103032 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fbxo11 F-box protein 11 increases expression ISO Arbutin results in increased expression of FBXO11 mRNA CTD PMID:17103032 NCBI chr17:88,298,287...88,373,473
Ensembl chr17:88,298,287...88,372,719
JBrowse link
G Fbxo16 F-box protein 16 increases expression ISO Arbutin results in increased expression of FBXO16 mRNA CTD PMID:17103032 NCBI chr14:65,504,067...65,561,422
Ensembl chr14:65,504,067...65,561,422
JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Arbutin results in decreased expression of FGF5 mRNA CTD PMID:17103032 NCBI chr 5:98,402,108...98,424,892
Ensembl chr 5:98,402,043...98,424,889
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO Arbutin results in decreased expression of FGFR3 mRNA CTD PMID:17103032 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Fmnl3 formin-like 3 decreases expression ISO Arbutin results in decreased expression of FMNL3 mRNA CTD PMID:17103032 NCBI chr15:99,215,091...99,268,375
Ensembl chr15:99,215,106...99,268,363
JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase decreases expression ISO Arbutin results in decreased expression of FPGT mRNA CTD PMID:17103032 NCBI chr 3:154,790,552...154,799,024
Ensembl chr 3:154,790,555...154,799,040
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 decreases expression ISO Arbutin results in decreased expression of FRAS1 mRNA CTD PMID:17103032 NCBI chr 5:96,518,622...96,932,592
Ensembl chr 5:96,521,814...96,932,587
JBrowse link
G Frmpd4 FERM and PDZ domain containing 4 decreases expression ISO Arbutin results in decreased expression of FRMPD4 mRNA CTD PMID:17103032 NCBI chr  X:166,254,297...167,360,230
Ensembl chr  X:166,254,305...167,360,227
JBrowse link
G Fshb follicle stimulating hormone beta increases expression EXP Arbutin results in increased expression of FSHB protein CTD PMID:29360751 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Galc galactosylceramidase increases expression ISO Arbutin results in increased expression of GALC mRNA CTD PMID:17103032 NCBI chr12:98,168,543...98,226,565
Ensembl chr12:98,168,553...98,225,718
JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 increases expression ISO Arbutin results in increased expression of GAREM1 mRNA CTD PMID:17103032 NCBI chr18:21,257,916...21,433,196
Ensembl chr18:21,260,258...21,433,195
JBrowse link
G Get3 guided entry of tail-anchored proteins factor 3, ATPase decreases expression ISO Arbutin results in decreased expression of GET3 mRNA CTD PMID:17103032 NCBI chr 8:85,744,558...85,751,916
Ensembl chr 8:85,744,560...85,751,910
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 decreases expression ISO Arbutin results in decreased expression of GIPC1 mRNA CTD PMID:17103032 NCBI chr 8:84,376,037...84,391,418
Ensembl chr 8:84,379,306...84,391,323
JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 decreases expression ISO Arbutin results in decreased expression of GLT8D2 mRNA CTD PMID:17103032 NCBI chr10:82,486,262...82,529,846
Ensembl chr10:82,486,267...82,526,484
JBrowse link
G Gm12695 predicted gene 12695 decreases expression ISO Arbutin results in decreased expression of C1ORF87 mRNA CTD PMID:17103032 NCBI chr 4:96,611,818...96,675,067
Ensembl chr 4:96,611,884...96,673,423
JBrowse link
G Gm3764 predicted gene 3764 decreases expression ISO Arbutin results in decreased expression of MIR9-1HG mRNA CTD PMID:17103032 NCBI chr 3:88,113,980...88,137,266
Ensembl chr 3:88,113,837...88,137,268
JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO Arbutin results in decreased expression of GMPR mRNA CTD PMID:17103032 NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276
JBrowse link
G Gnl2 guanine nucleotide binding protein nucleolar 2 increases expression ISO Arbutin results in increased expression of GNL2 mRNA CTD PMID:17103032 NCBI chr 4:124,920,866...124,949,175
Ensembl chr 4:124,910,378...124,949,173
JBrowse link
G Gpc3 glypican 3 decreases expression ISO Arbutin results in decreased expression of GPC3 mRNA CTD PMID:17103032 NCBI chr  X:51,361,303...51,702,851
Ensembl chr  X:51,361,303...51,702,827
JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial increases expression ISO Arbutin results in increased expression of GPD2 mRNA CTD PMID:17103032 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP
ISO
Arbutin results in increased expression of GPER1 protein CTD PMID:29360751 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555
JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO Arbutin results in decreased expression of GPR155 mRNA CTD PMID:17103032 NCBI chr 2:73,171,850...73,216,842
Ensembl chr 2:73,171,850...73,216,916
JBrowse link
G Gpr26 G protein-coupled receptor 26 decreases expression ISO Arbutin results in decreased expression of GPR26 mRNA CTD PMID:17103032 NCBI chr 7:131,567,891...131,587,362
Ensembl chr 7:131,568,189...131,596,134
JBrowse link
G Gpr55 G protein-coupled receptor 55 decreases expression ISO Arbutin results in decreased expression of GPR55 mRNA CTD PMID:17103032 NCBI chr 1:85,860,927...85,924,781
Ensembl chr 1:85,866,039...85,888,729
JBrowse link
G Gprc5d G protein-coupled receptor, family C, group 5, member D decreases expression ISO Arbutin results in decreased expression of GPRC5D mRNA CTD PMID:17103032 NCBI chr 6:135,082,989...135,095,281
Ensembl chr 6:135,082,989...135,095,281
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of GPT protein] CTD PMID:34346143 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsdma gasdermin A decreases expression ISO Arbutin results in decreased expression of GSDMA mRNA CTD PMID:17103032 NCBI chr11:98,555,163...98,568,534
Ensembl chr11:98,555,177...98,568,534
JBrowse link
G Gucy1a2 guanylate cyclase 1, soluble, alpha 2 decreases expression ISO Arbutin results in decreased expression of GUCY1A2 mRNA CTD PMID:17103032 NCBI chr 9:3,532,349...3,905,791
Ensembl chr 9:3,532,778...3,894,736
JBrowse link
G H1f1 H1.1 linker histone, cluster member increases expression ISO Arbutin results in increased expression of H1-1 mRNA CTD PMID:17103032 NCBI chr13:23,947,651...23,948,395
Ensembl chr13:23,947,649...23,948,389
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 increases expression ISO Arbutin results in increased expression of HAND1 mRNA CTD PMID:17103032 NCBI chr11:57,719,539...57,722,973
Ensembl chr11:57,719,531...57,723,644
JBrowse link
G Hlf hepatic leukemia factor decreases expression ISO Arbutin results in decreased expression of HLF mRNA CTD PMID:17103032 NCBI chr11:90,227,361...90,281,745
Ensembl chr11:90,227,362...90,281,721
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in decreased expression of HMOX1 mRNA] CTD PMID:34346143 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hoxb8 homeobox B8 decreases expression ISO Arbutin results in decreased expression of HOXB8 mRNA CTD PMID:17103032 NCBI chr11:96,170,227...96,176,151
Ensembl chr11:96,172,731...96,176,141
JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 decreases expression ISO Arbutin results in decreased expression of HPS3 mRNA CTD PMID:17103032 NCBI chr 3:20,050,109...20,089,478
Ensembl chr 3:20,050,109...20,089,479
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Arbutin results in decreased expression of HSD3B1 mRNA
Arbutin results in decreased expression of HSD3B1 mRNA; Arbutin results in decreased expression of HSD3B1 protein
CTD PMID:17103032 PMID:37783241 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Htatsf1 HIV TAT specific factor 1 increases expression ISO Arbutin results in increased expression of HTATSF1 mRNA CTD PMID:17103032 NCBI chr  X:56,098,930...56,112,543
Ensembl chr  X:56,098,943...56,112,543
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Arbutin results in decreased expression of IFIT3 mRNA CTD PMID:17103032 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 decreases expression ISO Arbutin results in decreased expression of IGDCC3 mRNA CTD PMID:17103032 NCBI chr 9:65,048,404...65,094,313
Ensembl chr 9:65,048,471...65,093,154
JBrowse link
G Il23a interleukin 23, alpha subunit p19 decreases expression ISO Arbutin results in decreased expression of IL23A mRNA CTD PMID:17103032 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Il3ra interleukin 3 receptor, alpha chain increases expression ISO Arbutin results in increased expression of IL3RA mRNA CTD PMID:17103032 NCBI chr14:8,114,270...8,123,851
Ensembl chr14:8,113,752...8,123,488
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of IL6 protein] CTD PMID:34346143 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer decreases expression ISO Arbutin results in decreased expression of IL6ST mRNA CTD PMID:17103032 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression ISO Arbutin results in decreased expression of INA mRNA CTD PMID:17103032 NCBI chr19:47,003,120...47,013,766
Ensembl chr19:47,003,137...47,013,766
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase, type II increases expression ISO Arbutin results in increased expression of INPP4B mRNA CTD PMID:17103032 NCBI chr 8:82,068,895...82,865,553
Ensembl chr 8:82,069,185...82,854,543
JBrowse link
G Jun jun proto-oncogene decreases expression ISO Arbutin results in decreased expression of JUN mRNA CTD PMID:17103032 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 decreases expression ISO Arbutin results in decreased expression of KCNAB3 mRNA CTD PMID:17103032 NCBI chr11:69,217,084...69,223,867
Ensembl chr11:69,217,084...69,223,868
JBrowse link
G Kctd17 potassium channel tetramerisation domain containing 17 decreases expression ISO Arbutin results in decreased expression of KCTD17 mRNA CTD PMID:17103032 NCBI chr15:78,312,578...78,323,503
Ensembl chr15:78,312,764...78,323,503
JBrowse link
G Kif26b kinesin family member 26B decreases expression ISO Arbutin results in decreased expression of KIF26B mRNA CTD PMID:17103032 NCBI chr 1:178,356,690...178,766,765
Ensembl chr 1:178,356,690...178,766,765
JBrowse link
G Klhl13 kelch-like 13 increases expression ISO Arbutin results in increased expression of KLHL13 mRNA CTD PMID:17103032 NCBI chr  X:23,085,510...23,231,340
Ensembl chr  X:23,085,510...23,231,321
JBrowse link
G Lctl lactase-like decreases expression ISO Arbutin results in decreased expression of LCTL mRNA CTD PMID:17103032 NCBI chr 9:64,024,399...64,045,400
Ensembl chr 9:64,024,429...64,045,400
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression ISO Arbutin results in decreased expression of LHCGR mRNA; Arbutin results in decreased expression of LHCGR protein CTD PMID:37783241 NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418
JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 decreases expression ISO Arbutin results in decreased expression of LRP5 mRNA CTD PMID:17103032 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564
JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 decreases expression ISO Arbutin results in decreased expression of LRP6 mRNA CTD PMID:17103032 NCBI chr 6:134,423,439...134,543,876
Ensembl chr 6:134,423,439...134,543,928
JBrowse link
G Lrrc4 leucine rich repeat containing 4 decreases expression ISO Arbutin results in decreased expression of LRRC4 mRNA CTD PMID:17103032 NCBI chr 6:28,828,125...28,831,746
Ensembl chr 6:28,661,830...28,831,746
JBrowse link
G Lrrtm4 leucine rich repeat transmembrane neuronal 4 decreases expression ISO Arbutin results in decreased expression of LRRTM4 mRNA CTD PMID:17103032 NCBI chr 6:79,995,828...80,787,143
Ensembl chr 6:79,995,860...80,787,124
JBrowse link
G Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) decreases expression ISO Arbutin results in decreased expression of MAFK mRNA CTD PMID:17103032 NCBI chr 5:139,777,291...139,788,409
Ensembl chr 5:139,777,268...139,788,408
JBrowse link
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 decreases expression ISO Arbutin results in decreased expression of MAP4K5 mRNA CTD PMID:17103032 NCBI chr12:69,850,531...69,939,937
Ensembl chr12:69,850,524...69,939,974
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases expression ISO Arbutin results in decreased expression of MAPK8 mRNA CTD PMID:17103032 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor increases expression ISO Arbutin results in increased expression of MCM8 mRNA CTD PMID:17103032 NCBI chr 2:132,658,061...132,686,117
Ensembl chr 2:132,658,061...132,686,117
JBrowse link
G Mdfi MyoD family inhibitor decreases expression ISO Arbutin results in decreased expression of MDFI mRNA CTD PMID:17103032 NCBI chr17:48,126,253...48,145,616
Ensembl chr17:48,126,253...48,145,616
JBrowse link
G Mfap4 microfibrillar-associated protein 4 decreases expression ISO Arbutin results in decreased expression of MFAP4 mRNA CTD PMID:17103032 NCBI chr11:61,376,257...61,379,536
Ensembl chr11:61,376,257...61,379,726
JBrowse link
G Midn midnolin decreases expression ISO Arbutin results in decreased expression of MIDN mRNA CTD PMID:17103032 NCBI chr10:79,984,106...79,994,202
Ensembl chr10:79,984,106...79,994,202
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 increases expression ISO Arbutin results in increased expression of MKI67 mRNA CTD PMID:17103032 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mmgt1 membrane magnesium transporter 1 increases expression ISO Arbutin results in increased expression of MMGT1 mRNA CTD PMID:17103032 NCBI chr  X:55,630,872...55,643,304
Ensembl chr  X:55,630,872...55,643,429
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like decreases expression ISO Arbutin results in decreased expression of MTHFD1L mRNA CTD PMID:17103032 NCBI chr10:3,918,282...4,117,081
Ensembl chr10:3,923,118...4,117,081
JBrowse link
G Mvd mevalonate (diphospho) decarboxylase decreases expression ISO Arbutin results in decreased expression of MVD mRNA CTD PMID:17103032 NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161
JBrowse link
G Myo3b myosin IIIB decreases expression ISO Arbutin results in decreased expression of MYO3B mRNA CTD PMID:17103032 NCBI chr 2:69,869,464...70,259,542
Ensembl chr 2:69,869,470...70,259,542
JBrowse link
G Ncald neurocalcin delta decreases expression ISO Arbutin results in decreased expression of NCALD mRNA CTD PMID:17103032 NCBI chr15:37,366,419...37,792,816
Ensembl chr15:37,366,419...37,792,814
JBrowse link
G Negr1 neuronal growth regulator 1 decreases expression ISO Arbutin results in decreased expression of NEGR1 mRNA CTD PMID:17103032 NCBI chr 3:156,266,082...157,022,101
Ensembl chr 3:156,267,431...157,022,082
JBrowse link
G Neu4 sialidase 4 increases expression ISO Arbutin results in increased expression of NEU4 mRNA CTD PMID:17103032 NCBI chr 1:93,948,215...93,956,056
Ensembl chr 1:93,948,173...93,956,056
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in decreased expression of NFE2L2 mRNA] CTD PMID:34346143 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nkd1 naked cuticle 1 decreases expression ISO Arbutin results in decreased expression of NKD1 mRNA CTD PMID:17103032 NCBI chr 8:89,247,961...89,321,515
Ensembl chr 8:89,247,982...89,321,512
JBrowse link
G Nmi N-myc (and STAT) interactor increases expression ISO Arbutin results in increased expression of NMI mRNA CTD PMID:17103032 NCBI chr 2:51,838,517...51,863,241
Ensembl chr 2:51,838,499...51,863,506
JBrowse link
G Noxred1 NADP+ dependent oxidoreductase domain containing 1 decreases expression ISO Arbutin results in decreased expression of NOXRED1 mRNA CTD PMID:17103032 NCBI chr12:87,267,897...87,285,375
Ensembl chr12:87,267,814...87,285,506
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of NQO1 mRNA] CTD PMID:34346143 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression ISO Arbutin results in increased expression of NR2F1 mRNA CTD PMID:17103032 NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876
JBrowse link
G Nrp2 neuropilin 2 increases expression ISO Arbutin results in increased expression of NRP2 mRNA CTD PMID:17103032 NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854
JBrowse link
G Ntf5 neurotrophin 5 decreases expression ISO Arbutin results in decreased expression of NTF4 mRNA CTD PMID:17103032 NCBI chr 7:45,063,119...45,066,603
Ensembl chr 7:45,063,119...45,066,603
JBrowse link
G Olfml1 olfactomedin-like 1 decreases expression ISO Arbutin results in decreased expression of OLFML1 mRNA CTD PMID:17103032 NCBI chr 7:107,166,640...107,190,572
Ensembl chr 7:107,166,653...107,190,301
JBrowse link
G Osbp2 oxysterol binding protein 2 decreases expression ISO Arbutin results in decreased expression of OSBP2 mRNA CTD PMID:17103032 NCBI chr11:3,653,731...3,814,000
Ensembl chr11:3,653,731...3,813,903
JBrowse link
G Osbpl11 oxysterol binding protein-like 11 increases expression ISO Arbutin results in increased expression of OSBPL11 mRNA CTD PMID:17103032 NCBI chr16:33,005,441...33,063,682
Ensembl chr16:33,005,441...33,063,682
JBrowse link
G Otx1 orthodenticle homeobox 1 decreases expression ISO Arbutin results in decreased expression of OTX1 mRNA CTD PMID:17103032 NCBI chr11:21,944,764...21,954,044
Ensembl chr11:21,944,764...21,952,897
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 decreases expression ISO Arbutin results in decreased expression of PACSIN2 mRNA CTD PMID:17103032 NCBI chr15:83,259,812...83,348,800
Ensembl chr15:83,259,808...83,348,807
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase increases expression ISO Arbutin results in increased expression of PARG mRNA CTD PMID:17103032 NCBI chr14:31,923,900...32,020,671
Ensembl chr14:31,923,906...32,019,507
JBrowse link
G Pcgf6 polycomb group ring finger 6 increases expression ISO Arbutin results in increased expression of PCGF6 mRNA CTD PMID:17103032 NCBI chr19:47,022,056...47,039,379
Ensembl chr19:47,022,056...47,039,345
JBrowse link
G Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 increases expression ISO Arbutin results in increased expression of PCMTD2 mRNA CTD PMID:17103032 NCBI chr 2:181,471,952...181,499,253
Ensembl chr 2:181,479,647...181,499,254
JBrowse link
G Pcnx2 pecanex homolog 2 decreases expression ISO Arbutin results in decreased expression of PCNX2 mRNA CTD PMID:17103032 NCBI chr 8:126,478,243...126,625,056
Ensembl chr 8:126,478,247...126,625,056
JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO Arbutin results in decreased expression of PDZK1 mRNA CTD PMID:17103032 NCBI chr 3:96,736,772...96,778,242
Ensembl chr 3:96,736,600...96,778,242
JBrowse link
G Perm1 PPARGC1 and ESRR induced regulator, muscle 1 decreases expression ISO Arbutin results in decreased expression of PERM1 mRNA CTD PMID:17103032 NCBI chr 4:156,287,724...156,305,766
Ensembl chr 4:156,300,325...156,305,764
JBrowse link
G Pf4 platelet factor 4 decreases expression ISO Arbutin results in decreased expression of PF4 mRNA CTD PMID:17103032 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
JBrowse link
G Pgm2 phosphoglucomutase 2 increases expression ISO Arbutin results in increased expression of PGM2 mRNA CTD PMID:17103032 NCBI chr 5:64,250,258...64,285,698
Ensembl chr 5:64,250,293...64,285,694
JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q decreases expression ISO Arbutin results in decreased expression of PIGQ mRNA CTD PMID:17103032 NCBI chr17:26,145,398...26,161,855
Ensembl chr17:26,145,395...26,163,910
JBrowse link
G Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 decreases expression ISO Arbutin results in decreased expression of PIN1 mRNA CTD PMID:17103032 NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880
JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Arbutin results in increased expression of PITPNB mRNA CTD PMID:17103032 NCBI chr 5:111,478,563...111,536,225
Ensembl chr 5:111,478,629...111,536,225
JBrowse link
G Pkhd1 polycystic kidney and hepatic disease 1 decreases expression ISO Arbutin results in decreased expression of PKHD1 mRNA CTD PMID:17103032 NCBI chr 1:20,128,003...20,688,306
Ensembl chr 1:20,128,003...20,688,288
JBrowse link
G Poglut2 protein O-glucosyltransferase 2 increases expression ISO Arbutin results in increased expression of POGLUT2 mRNA CTD PMID:17103032 NCBI chr 1:44,143,060...44,158,844
Ensembl chr 1:44,145,706...44,157,968
JBrowse link
G Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) increases expression ISO Arbutin results in increased expression of POLE2 mRNA CTD PMID:17103032 NCBI chr12:69,248,547...69,274,979
Ensembl chr12:69,248,547...69,274,969
JBrowse link
G Pphln1 periphilin 1 increases expression ISO Arbutin results in increased expression of PPHLN1 mRNA CTD PMID:17103032 NCBI chr15:93,296,243...93,389,794
Ensembl chr15:93,296,231...93,389,391
JBrowse link
G Prg2 proteoglycan 2, bone marrow decreases expression ISO Arbutin results in decreased expression of PRG2 mRNA CTD PMID:17103032 NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976
JBrowse link
G Prkx protein kinase, X-linked decreases expression ISO Arbutin results in decreased expression of PRKX mRNA CTD PMID:17103032 NCBI chr  X:76,804,578...76,839,545
Ensembl chr  X:76,805,017...76,839,884
JBrowse link
G Prmt2 protein arginine N-methyltransferase 2 decreases expression ISO Arbutin results in decreased expression of PRMT2 mRNA CTD PMID:17103032 NCBI chr10:76,043,060...76,073,699
Ensembl chr10:76,043,056...76,073,699
JBrowse link
G Prr18 proline rich 18 decreases expression ISO Arbutin results in decreased expression of PRR18 mRNA CTD PMID:17103032 NCBI chr17:8,546,378...8,562,945
Ensembl chr17:8,556,291...8,562,945
JBrowse link
G Prrx1 paired related homeobox 1 decreases expression ISO Arbutin results in decreased expression of PRRX1 mRNA CTD PMID:17103032 NCBI chr 1:163,072,688...163,142,714
Ensembl chr 1:163,072,688...163,141,279
JBrowse link
G Prss2 serine protease 2 decreases expression ISO Arbutin results in decreased expression of PRSS2 mRNA CTD PMID:17103032 NCBI chr 6:41,498,710...41,502,013
Ensembl chr 6:41,498,721...41,502,013
JBrowse link
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 decreases expression ISO Arbutin results in decreased expression of PSMD13 mRNA CTD PMID:17103032 NCBI chr 7:140,462,307...140,478,555
Ensembl chr 7:140,461,881...140,478,556
JBrowse link
G Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 decreases expression ISO Arbutin results in decreased expression of PSMD3 mRNA CTD PMID:17103032 NCBI chr11:98,573,380...98,586,804
Ensembl chr11:98,573,380...98,586,805
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein subunit 1 increases expression ISO Arbutin results in increased expression of RAB3GAP1 mRNA CTD PMID:17103032 NCBI chr 1:127,796,492...127,871,612
Ensembl chr 1:127,796,510...127,871,605
JBrowse link
G Rab6b RAB6B, member RAS oncogene family decreases expression ISO Arbutin results in decreased expression of RAB6B mRNA CTD PMID:17103032 NCBI chr 9:102,988,866...103,062,475
Ensembl chr 9:102,988,986...103,062,475
JBrowse link
G Rasgef1b RasGEF domain family, member 1B decreases expression ISO Arbutin results in decreased expression of RASGEF1B mRNA CTD PMID:17103032 NCBI chr 5:99,365,279...99,400,786
Ensembl chr 5:99,365,285...99,876,924
JBrowse link
G Rnf208 ring finger protein 208 decreases expression ISO Arbutin results in decreased expression of RNF208 mRNA CTD PMID:17103032 NCBI chr 2:25,132,941...25,134,273
Ensembl chr 2:25,132,941...25,134,274
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase polypeptide 3 increases expression ISO Arbutin results in increased expression of RPS6KA3 mRNA CTD PMID:17103032 NCBI chr  X:158,038,652...158,151,240
Ensembl chr  X:157,993,303...158,151,240
JBrowse link
G Rsbn1 rosbin, round spermatid basic protein 1 decreases expression ISO Arbutin results in decreased expression of RSBN1 mRNA CTD PMID:17103032 NCBI chr 3:103,821,412...103,873,952
Ensembl chr 3:103,821,436...103,873,952
JBrowse link
G Saa4 serum amyloid A 4 decreases expression ISO Arbutin results in decreased expression of SAA4 mRNA CTD PMID:17103032 NCBI chr 7:46,377,416...46,382,027
Ensembl chr 7:46,377,422...46,382,027
JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) increases expression ISO Arbutin results in increased expression of SCCPDH mRNA CTD PMID:17103032 NCBI chr 1:179,495,796...179,514,754
Ensembl chr 1:179,495,775...179,514,754
JBrowse link
G Scn1b sodium channel, voltage-gated, type I, beta increases expression ISO Arbutin results in increased expression of SCN1B mRNA CTD PMID:17103032 NCBI chr 7:30,815,949...30,826,436
Ensembl chr 7:30,815,949...30,826,428
JBrowse link
G Sdc4 syndecan 4 decreases expression ISO Arbutin results in decreased expression of SDC4 mRNA CTD PMID:17103032 NCBI chr 2:164,266,167...164,285,512
Ensembl chr 2:164,266,167...164,285,807
JBrowse link
G Semg1 semenogelin 1 decreases expression ISO Arbutin results in decreased expression of SEMG1 mRNA CTD PMID:17103032 NCBI chr 2:164,077,849...164,080,261
Ensembl chr 2:164,077,849...164,080,386
JBrowse link
G Serpina5 serine (or cysteine) peptidase inhibitor, clade A, member 5 decreases expression ISO Arbutin results in decreased expression of SERPINA5 mRNA CTD PMID:17103032 NCBI chr12:104,065,572...104,072,397
Ensembl chr12:104,067,372...104,072,396
JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 decreases expression ISO Arbutin results in decreased expression of SERPIND1 mRNA CTD PMID:17103032 NCBI chr16:17,149,235...17,161,438
Ensembl chr16:17,149,235...17,161,439
JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 increases expression ISO Arbutin results in increased expression of SF3B1 mRNA CTD PMID:17103032 NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640
JBrowse link
G Sfrp5 secreted frizzled-related sequence protein 5 decreases expression ISO Arbutin results in decreased expression of SFRP5 mRNA CTD PMID:17103032 NCBI chr19:42,186,410...42,190,691
Ensembl chr19:42,186,410...42,190,691
JBrowse link
G Sfxn2 sideroflexin 2 decreases expression ISO Arbutin results in decreased expression of SFXN2 mRNA CTD PMID:17103032 NCBI chr19:46,561,798...46,585,340
Ensembl chr19:46,561,804...46,586,505
JBrowse link
G Sh3gl2 SH3-domain GRB2-like 2 decreases expression ISO Arbutin results in decreased expression of SH3GL2 mRNA CTD PMID:17103032 NCBI chr 4:85,123,663...85,307,617
Ensembl chr 4:85,123,363...85,557,432
JBrowse link
G Sin3b transcriptional regulator, SIN3B (yeast) decreases expression ISO Arbutin results in decreased expression of SIN3B mRNA CTD PMID:17103032 NCBI chr 8:73,449,898...73,484,831
Ensembl chr 8:73,449,913...73,484,829
JBrowse link
G Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 decreases expression ISO Arbutin results in decreased expression of SLC13A2 mRNA CTD PMID:17103032 NCBI chr11:78,288,102...78,313,107
Ensembl chr11:78,287,913...78,313,043
JBrowse link
G Slc15a3 solute carrier family 15, member 3 decreases expression ISO Arbutin results in decreased expression of SLC15A3 mRNA CTD PMID:17103032 NCBI chr19:10,819,908...10,835,279
Ensembl chr19:10,817,091...10,836,726
JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 decreases expression ISO Arbutin results in decreased expression of SLC18A2 mRNA CTD PMID:17103032 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444
JBrowse link
G Slc23a3 solute carrier family 23 (nucleobase transporters), member 3 increases expression ISO Arbutin results in increased expression of SLC23A3 mRNA CTD PMID:17103032 NCBI chr 1:75,102,185...75,112,113
Ensembl chr 1:75,102,185...75,110,534
JBrowse link
G Slc25a2 solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2 decreases expression ISO Arbutin results in decreased expression of SLC25A2 mRNA CTD PMID:17103032 NCBI chr18:37,770,431...37,771,776
Ensembl chr18:37,770,431...37,771,776
JBrowse link
G Slc27a4 solute carrier family 27 (fatty acid transporter), member 4 decreases expression ISO Arbutin results in decreased expression of SLC27A4 mRNA CTD PMID:17103032 NCBI chr 2:29,692,646...29,707,534
Ensembl chr 2:29,692,646...29,707,534
JBrowse link
G Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 decreases expression ISO Arbutin results in decreased expression of SLC7A3 mRNA CTD PMID:17103032 NCBI chr  X:100,122,752...100,134,058
Ensembl chr  X:100,122,816...100,129,626
JBrowse link
G Slco5a1 solute carrier organic anion transporter family, member 5A1 decreases expression ISO Arbutin results in decreased expression of SLCO5A1 mRNA CTD PMID:17103032 NCBI chr 1:12,936,773...13,063,043
Ensembl chr 1:12,936,773...13,062,874
JBrowse link
G Snip1 Smad nuclear interacting protein 1 decreases expression ISO Arbutin results in decreased expression of SNIP1 mRNA CTD PMID:17103032 NCBI chr 4:124,960,465...124,967,836
Ensembl chr 4:124,960,465...124,967,835
JBrowse link
G Socs4 suppressor of cytokine signaling 4 decreases expression ISO Arbutin results in decreased expression of SOCS4 mRNA CTD PMID:17103032 NCBI chr14:47,514,377...47,533,559
Ensembl chr14:47,514,388...47,533,559
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO Arbutin inhibits the reaction [potassium bromate results in decreased activity of SOD1 protein] CTD PMID:36284482 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Spata13 spermatogenesis associated 13 increases expression ISO Arbutin results in increased expression of SPATA13 mRNA CTD PMID:17103032 NCBI chr14:60,722,617...61,002,005
Ensembl chr14:60,871,450...61,002,005
JBrowse link
G Spata20 spermatogenesis associated 20 decreases expression ISO Arbutin results in decreased expression of SPATA20 mRNA CTD PMID:17103032 NCBI chr11:94,369,730...94,376,136
Ensembl chr11:94,369,730...94,377,005
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 increases expression ISO Arbutin results in increased expression of SPTLC1 mRNA CTD PMID:17103032 NCBI chr13:53,486,784...53,531,401
Ensembl chr13:53,486,784...53,531,433
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity
decreases expression
ISO Arbutin results in decreased activity of SRD5A1 protein
Arbutin results in decreased expression of SRD5A1 mRNA; Arbutin results in decreased expression of SRD5A1 protein
CTD PMID:37783241 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
JBrowse link
G Stard8 StAR related lipid transfer domain containing 8 decreases expression ISO Arbutin results in decreased expression of STARD8 mRNA CTD PMID:17103032 NCBI chr  X:98,046,539...98,118,334
Ensembl chr  X:98,046,854...98,118,334
JBrowse link
G Syde1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) decreases expression ISO Arbutin results in decreased expression of SYDE1 mRNA CTD PMID:17103032 NCBI chr10:78,420,336...78,427,798
Ensembl chr10:78,420,337...78,427,798
JBrowse link
G Sympk symplekin decreases expression ISO Arbutin results in decreased expression of SYMPK mRNA CTD PMID:17103032 NCBI chr 7:18,758,321...18,788,542
Ensembl chr 7:18,758,302...18,788,543
JBrowse link
G Tal1 T cell acute lymphocytic leukemia 1 decreases expression ISO Arbutin results in decreased expression of TAL1 mRNA CTD PMID:17103032 NCBI chr 4:114,913,623...114,928,952
Ensembl chr 4:114,913,623...114,928,952
JBrowse link
G Tardbp TAR DNA binding protein increases expression ISO Arbutin results in increased expression of TARDBP mRNA CTD PMID:17103032 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476
JBrowse link
G Tcf12 transcription factor 12 increases expression ISO Arbutin results in increased expression of TCF12 mRNA CTD PMID:17103032 NCBI chr 9:71,751,534...72,019,611
Ensembl chr 9:71,749,970...72,019,153
JBrowse link
G Tes testin LIM domain protein increases expression ISO Arbutin results in increased expression of TES mRNA CTD PMID:17103032 NCBI chr 6:17,065,148...17,105,824
Ensembl chr 6:17,065,148...17,105,827
JBrowse link
G Tex13b testis expressed 13B decreases expression ISO Arbutin results in decreased expression of TEX13B mRNA CTD PMID:17103032 NCBI chr  X:139,709,056...139,714,182
Ensembl chr  X:139,709,056...139,714,182
JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression ISO Arbutin results in decreased expression of TGFB3 mRNA CTD PMID:17103032 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815
JBrowse link
G Tll1 tolloid-like decreases expression ISO Arbutin results in decreased expression of TLL1 mRNA CTD PMID:17103032 NCBI chr 8:64,466,132...64,659,043
Ensembl chr 8:64,467,965...64,659,305
JBrowse link
G Tmem59l transmembrane protein 59-like decreases expression ISO Arbutin results in decreased expression of TMEM59L mRNA CTD PMID:17103032 NCBI chr 8:70,936,505...70,939,998
Ensembl chr 8:70,936,517...70,940,008
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:34346143 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tor4a torsin family 4, member A decreases expression ISO Arbutin results in decreased expression of TOR4A mRNA CTD PMID:17103032 NCBI chr 2:25,082,732...25,086,825
Ensembl chr 2:25,082,978...25,086,898
JBrowse link
G Tram2 translocating chain-associating membrane protein 2 decreases expression ISO Arbutin results in decreased expression of TRAM2 mRNA CTD PMID:17103032 NCBI chr 1:21,071,621...21,149,449
Ensembl chr 1:21,066,523...21,149,453
JBrowse link
G Treh trehalase (brush-border membrane glycoprotein) decreases expression ISO Arbutin results in decreased expression of TREH mRNA CTD PMID:17103032 NCBI chr 9:44,584,530...44,597,602
Ensembl chr 9:44,584,530...44,597,602
JBrowse link
G Tsc1 TSC complex subunit 1 increases expression ISO Arbutin results in increased expression of TSC1 mRNA CTD PMID:17103032 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Tsc22d2 TSC22 domain family, member 2 decreases expression ISO Arbutin results in decreased expression of TSC22D2 mRNA CTD PMID:17103032 NCBI chr 3:58,322,123...58,374,208
Ensembl chr 3:58,322,136...58,374,204
JBrowse link
G Tshz2 teashirt zinc finger family member 2 decreases expression ISO Arbutin results in decreased expression of TSHZ2 mRNA CTD PMID:17103032 NCBI chr 2:169,474,430...169,914,671
Ensembl chr 2:169,474,933...169,913,736
JBrowse link
G Tspoap1 TSPO associated protein 1 decreases expression ISO Arbutin results in decreased expression of TSPOAP1 mRNA CTD PMID:17103032 NCBI chr11:87,649,022...87,676,754
Ensembl chr11:87,651,367...87,676,754
JBrowse link
G Ttc22 tetratricopeptide repeat domain 22 decreases expression ISO Arbutin results in decreased expression of TTC22 mRNA CTD PMID:17103032 NCBI chr 4:106,479,646...106,497,393
Ensembl chr 4:106,479,629...106,497,386
JBrowse link
G Tulp3 TUB like protein 3 decreases expression ISO Arbutin results in decreased expression of TULP3 mRNA CTD PMID:17103032 NCBI chr 6:128,298,103...128,332,833
Ensembl chr 6:128,298,124...128,332,814
JBrowse link
G Tyr tyrosinase decreases expression
decreases activity
EXP Arbutin results in decreased expression of TYR mRNA
Arbutin results in decreased activity of TYR protein
CTD PMID:21071833 PMID:22705713 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
G Ube2d4 ubiquitin-conjugating enzyme E2D 4 decreases expression ISO Arbutin results in decreased expression of UBE2D4 mRNA CTD PMID:17103032 Ensembl chr15:58,718,439...58,719,170 JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M decreases expression ISO Arbutin results in decreased expression of UBE2M mRNA CTD PMID:17103032 NCBI chr 7:12,769,047...12,772,202
Ensembl chr 7:12,769,047...12,772,202
JBrowse link
G Ubqln1 ubiquilin 1 increases expression ISO Arbutin results in increased expression of UBQLN1 mRNA CTD PMID:17103032 NCBI chr13:58,323,970...58,363,467
Ensembl chr13:58,323,970...58,363,467
JBrowse link
G Usp44 ubiquitin specific peptidase 44 decreases expression ISO Arbutin results in decreased expression of USP44 mRNA CTD PMID:17103032 NCBI chr10:93,655,831...93,696,792
Ensembl chr10:93,667,417...93,693,950
JBrowse link
G Utp11 UTP11 small subunit processome component increases expression ISO Arbutin results in increased expression of UTP11 mRNA CTD PMID:17103032 NCBI chr 4:124,571,173...124,587,395
Ensembl chr 4:124,571,953...124,587,393
JBrowse link
G Vps13b vacuolar protein sorting 13B decreases expression ISO Arbutin results in decreased expression of VPS13B mRNA CTD PMID:17103032 NCBI chr15:35,371,264...35,931,375
Ensembl chr15:35,371,306...35,931,375
JBrowse link
G Vps39 VPS39 HOPS complex subunit increases expression ISO Arbutin results in increased expression of VPS39 mRNA CTD PMID:17103032 NCBI chr 2:120,146,942...120,183,618
Ensembl chr 2:120,146,942...120,183,618
JBrowse link
G Vwa3a von Willebrand factor A domain containing 3A decreases expression ISO Arbutin results in decreased expression of VWA3A mRNA CTD PMID:17103032 NCBI chr 7:120,336,554...120,404,769
Ensembl chr 7:120,338,541...120,404,965
JBrowse link
G Wnt10a wingless-type MMTV integration site family, member 10A decreases expression ISO Arbutin results in decreased expression of WNT10A mRNA CTD PMID:17103032 NCBI chr 1:74,831,178...74,843,335
Ensembl chr 1:74,830,675...74,843,338
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 increases expression ISO Arbutin results in increased expression of ZBTB20 mRNA CTD PMID:17103032 NCBI chr16:42,728,008...43,462,981
Ensembl chr16:42,696,244...43,462,965
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B decreases expression ISO Arbutin results in decreased expression of ZBTB7B mRNA CTD PMID:17103032 NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083
JBrowse link
G Zdhhc2 zinc finger, DHHC domain containing 2 decreases expression ISO Arbutin results in decreased expression of ZDHHC2 mRNA CTD PMID:17103032 NCBI chr 8:40,876,526...40,946,178
Ensembl chr 8:40,876,856...40,963,309
JBrowse link
G Zfp354b zinc finger protein 354B decreases expression ISO Arbutin results in decreased expression of ZNF354B mRNA CTD PMID:17103032 NCBI chr11:50,812,613...50,822,486
Ensembl chr11:50,812,650...50,822,460
JBrowse link
G Zfp414 zinc finger protein 414 decreases expression ISO Arbutin results in decreased expression of ZNF414 mRNA CTD PMID:17103032 NCBI chr17:33,848,066...33,850,690
Ensembl chr17:33,848,064...33,850,753
JBrowse link
G Zfp870 zinc finger protein 870 increases expression ISO Arbutin results in increased expression of ZNF670 mRNA CTD PMID:17103032 NCBI chr17:33,098,193...33,110,621
Ensembl chr17:33,098,193...33,110,616
JBrowse link
G Zkscan16 zinc finger with KRAB and SCAN domains 16 decreases expression ISO Arbutin results in decreased expression of ZNF483 mRNA CTD PMID:17103032 NCBI chr 4:58,943,568...58,962,624
Ensembl chr 4:58,943,628...58,958,355
JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 decreases expression ISO Arbutin results in decreased expression of ZKSCAN7 mRNA CTD PMID:17103032 NCBI chr 9:122,715,883...122,727,684
Ensembl chr 9:122,714,750...122,727,683
JBrowse link
G Zp2 zona pellucida glycoprotein 2 decreases expression ISO Arbutin results in decreased expression of ZP2 mRNA CTD PMID:17103032 NCBI chr 7:119,725,985...119,744,514
Ensembl chr 7:119,725,995...119,744,514
JBrowse link
kaempferol 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein] CTD PMID:35537655 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Cat catalase multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein] CTD PMID:35537655 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] CTD PMID:22210036 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA] CTD PMID:22210036 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein] CTD PMID:35537655 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Il10 interleukin 10 multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein] CTD PMID:35537655 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP astragalin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:22210036 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:22210036 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch1 notch 1 multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] CTD PMID:35537655 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:22210036 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein] CTD PMID:35537655 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:22210036 PMID:35537655 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
liquiritin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions EXP [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 mRNA CTD PMID:36008890 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions EXP [liquiritin co-treated with 1-Naphthylisothiocyanate] results in decreased expression of ABCC2 mRNA CTD PMID:36008890 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions EXP [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC3 mRNA CTD PMID:36008890 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions EXP [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC4 mRNA CTD PMID:36008890 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP
ISO
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of CCL2 mRNA]
liquiritin inhibits the reaction [Monocrotaline results in increased expression of CCL2 mRNA]
CTD PMID:31589899 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein CTD PMID:21800547 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLC mRNA]
liquiritin results in increased expression of GCLC protein
CTD PMID:29908794 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions
increases expression
ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA]
liquiritin results in increased expression of GCLM protein
CTD PMID:29908794 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO
EXP
liquiritin inhibits the reaction [Monocrotaline results in increased activity of GPT protein]
liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of GPT protein]
CTD PMID:31589899 PMID:36008890 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsr glutathione reductase multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GSR mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GSR protein] CTD PMID:29908794 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP
liquiritin inhibits the reaction [Monocrotaline results in increased expression of HMOX1 mRNA]
[liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of HMOX1 mRNA; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of HMOX1 protein]
CTD PMID:29908794 PMID:36008890 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions EXP
ISO
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of CCL2 mRNA]; liquiritin inhibits the reaction [HSPD1 protein results in increased expression of IL6 mRNA]; liquiritin inhibits the reaction [HSPD1 protein results in increased expression of NOS2 mRNA]; liquiritin inhibits the reaction [HSPD1 protein results in increased expression of RELA protein]
liquiritin inhibits the reaction [Monocrotaline affects the expression of HSPD1 protein]
CTD PMID:31589899 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B protein] CTD PMID:36008890 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of IL6 mRNA]
liquiritin inhibits the reaction [Monocrotaline results in increased expression of IL6 mRNA]
CTD PMID:31589899 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions EXP liquiritin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of KEAP1 protein] CTD PMID:36008890 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of MMP9 protein] CTD PMID:29908794 PMID:31589899 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased activity of MPO protein] CTD PMID:31589899 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
decreases response to substance
ISO
EXP
liquiritin inhibits the reaction [Monocrotaline results in decreased expression of NFE2L2 mRNA]
liquiritin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of NFE2L2 protein]
NFE2L2 gene mutant form results in decreased susceptibility to liquiritin
CTD PMID:29908794 PMID:36008890 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO
EXP
liquiritin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of NOS2 mRNA]
CTD PMID:31589899 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO
EXP
liquiritin inhibits the reaction [Monocrotaline results in decreased expression of NQO1 mRNA]
[liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of NQO1 mRNA
CTD PMID:29908794 PMID:36008890 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein] CTD PMID:36008890 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP
ISO
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of RELA protein]
liquiritin inhibits the reaction [Monocrotaline results in increased expression of RELA protein]
CTD PMID:31589899 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SIRT1 mRNA]; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SIRT1 protein] CTD PMID:36008890 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 multiple interactions EXP liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA] CTD PMID:36008890 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of SQSTM1 protein] CTD PMID:29908794 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of TLR4 protein] CTD PMID:31589899 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein] CTD PMID:36008890 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Txn2 thioredoxin 2 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXN2 mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXN2 protein] CTD PMID:29908794 NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXNRD2 mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXNRD2 protein] CTD PMID:29908794 NCBI chr16:18,245,167...18,297,823
Ensembl chr16:18,245,134...18,297,823
JBrowse link
loganin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP loganin results in decreased activity of ACHE protein CTD PMID:19666019 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] CTD PMID:35279615 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression EXP loganin results in increased expression of BCL2 mRNA CTD PMID:20966881 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp1 caspase 1 multiple interactions ISO
EXP
loganin inhibits the reaction [Glucose results in increased expression of CASP1 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of CASP1 protein]
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]
CTD PMID:37473909 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 decreases expression EXP loganin results in decreased expression of CASP3 mRNA CTD PMID:20966881 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 decreases expression EXP loganin results in decreased expression of CASP9 mRNA CTD PMID:20966881 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression EXP loganin affects the expression of CCL2 protein CTD PMID:21864639 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide affects expression EXP loganin affects the expression of CYBA protein CTD PMID:21864639 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO
EXP
loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [Glucose results in increased expression of GSDMD protein]
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]
CTD PMID:37473909 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Hmox1 heme oxygenase 1 affects expression EXP loganin affects the expression of HMOX1 protein CTD PMID:21864639 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il18 interleukin 18 multiple interactions ISO
EXP
loganin inhibits the reaction [Glucose results in increased expression of IL18 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of IL18 protein]
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA]
CTD PMID:37473909 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
loganin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; loganin inhibits the reaction [Glucose results in increased expression of IL1B protein]
CTD PMID:35279615 PMID:37473909 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:35279615 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Lep leptin affects expression EXP loganin affects the expression of LEP protein CTD PMID:21864639 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects expression EXP loganin affects the expression of NFE2L2 protein CTD PMID:21864639 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP
ISO
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein]
loganin inhibits the reaction [Glucose results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of NLRP3 protein]
CTD PMID:37473909 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible affects expression EXP loganin affects the expression of NOS2 protein CTD PMID:21864639 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nox4 NADPH oxidase 4 affects expression EXP loganin affects the expression of NOX4 protein CTD PMID:21864639 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression EXP loganin affects the expression of PTGS2 protein CTD PMID:21864639 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) affects expression
multiple interactions
EXP
ISO
loganin affects the expression of RELA protein
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of RELA protein]
CTD PMID:21864639 PMID:35279615 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein]
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein]
CTD PMID:35279615 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA] CTD PMID:35279615 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:35279615 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 decreases expression EXP loganin results in decreased expression of TNFSF11 mRNA CTD PMID:20966881 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
luteolin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
decreases phosphorylation
ISO [luteolin-7-glucoside co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein
luteolin-7-glucoside results in decreased phosphorylation of AKT1 protein
CTD PMID:31157476 PMID:34165247 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Bax BCL2-associated X protein increases expression ISO luteolin-7-glucoside results in increased expression of BAX protein CTD PMID:34165247 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
ISO luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
luteolin-7-glucoside results in decreased expression of BCL2 protein
CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO luteolin-7-glucoside results in decreased expression of BCL2L1 protein CTD PMID:34165247 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO luteolin-7-glucoside results in increased expression of BID protein alternative form CTD PMID:34165247 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of CASP3 protein]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein] CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 increases cleavage ISO luteolin-7-glucoside results in increased cleavage of CASP8 protein CTD PMID:34165247 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 increases cleavage ISO luteolin-7-glucoside results in increased cleavage of CASP9 protein CTD PMID:34165247 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31157476 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO luteolin-7-glucoside results in decreased expression of CCNA2 protein CTD PMID:34165247 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO luteolin-7-glucoside results in decreased expression of CCNB1 protein CTD PMID:34165247 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases phosphorylation ISO luteolin-7-glucoside results in decreased phosphorylation of CDK1 protein CTD PMID:34165247 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO luteolin-7-glucoside results in decreased expression of CDK2 protein CTD PMID:34165247 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO luteolin-7-glucoside results in increased expression of CDKN1A protein CTD PMID:34165247 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
increases activity
ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]
luteolin-7-glucoside results in increased activity of ESR1 protein
CTD PMID:31381935 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions
increases activity
ISO 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]
luteolin-7-glucoside results in increased activity of ESR2 protein
CTD PMID:31381935 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO luteolin-7-glucoside results in increased expression of FAS protein CTD PMID:34165247 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein] CTD PMID:31381935 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Il6 interleukin 6 multiple interactions EXP luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein] CTD PMID:11123379 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]
luteolin-7-glucoside results in decreased phosphorylation of MAPK1 protein
CTD PMID:31381935 PMID:34165247 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]
luteolin-7-glucoside results in decreased phosphorylation of MAPK3 protein
CTD PMID:31381935 PMID:34165247 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage
multiple interactions
ISO luteolin-7-glucoside results in increased cleavage of PARP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; SB 203580 promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; U 0126 inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]
CTD PMID:34165247 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 increases expression ISO luteolin-7-glucoside results in increased expression of RIPK1 protein CTD PMID:34165247 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein] CTD PMID:31381935 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein] CTD PMID:11123379 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression ISO luteolin-7-glucoside results in increased expression of TNFRSF1A protein CTD PMID:34165247 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp3 aquaporin 3 multiple interactions ISO [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific decreases activity ISO malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD PMID:23731018 PMID:30611791 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
monotropein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of kappaB kinase beta multiple interactions EXP monotropein inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:23261679 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:23261679 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP monotropein inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:23261679 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP monotropein inhibits the reaction [Dextran Sulfate affects the localization of NFKB1 protein]; monotropein inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] CTD PMID:23261679 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
decreases degradation
EXP monotropein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
monotropein results in decreased degradation of NFKBIA protein
CTD PMID:23261679 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP monotropein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23261679 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP monotropein inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:23261679 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP monotropein inhibits the reaction [Dextran Sulfate affects the localization of RELA protein]; monotropein inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:23261679 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:23261679 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
neomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCA1 mRNA CTD PMID:36464106 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of ABCB11 mRNA; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB11 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB1A mRNA CTD PMID:36464106 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of ABCC3 mRNA; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA CTD PMID:36464106 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA CTD PMID:36464106 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole co-treated with elemicin] results in increased expression of ACACA mRNA CTD PMID:34979169 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2 protein CTD PMID:30545405 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACE2 protein CTD PMID:30545405 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Ada adenosine deaminase decreases activity
multiple interactions
EXP Neomycin results in decreased activity of ADA protein
Tetrachlorodibenzodioxin inhibits the reaction [Neomycin results in decreased activity of ADA protein]
CTD PMID:7853360 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole co-treated with elemicin] results in increased expression of ADIPOQ mRNA CTD PMID:34979169 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Ahsg alpha-2-HS-glycoprotein multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of AHSG protein CTD PMID:30545405 NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199
JBrowse link
G Aldob aldolase B, fructose-bisphosphate multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOB protein CTD PMID:30545405 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions
increases expression
EXP peoniflorin inhibits the reaction [Neomycin results in increased expression of APAF1 mRNA] CTD PMID:29292089 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Arg2 arginase type II multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ARPC3 protein CTD PMID:30545405 NCBI chr 5:122,529,941...122,544,244
Ensembl chr 5:122,529,941...122,552,247
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ASAH1 protein CTD PMID:30545405 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP1A1 protein CTD PMID:30545405 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein CTD PMID:30545405 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5MF protein CTD PMID:30545405 NCBI chr 5:145,120,514...145,128,351
Ensembl chr 5:145,120,508...145,128,872
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5PD protein CTD PMID:30545405 NCBI chr11:115,306,517...115,310,775
Ensembl chr11:115,306,515...115,310,788
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5PF protein CTD PMID:30545405 NCBI chr16:84,624,754...84,632,495
Ensembl chr16:84,624,754...84,632,513
JBrowse link
G B3galt5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of B3GALT5 protein CTD PMID:30545405 NCBI chr16:96,037,001...96,121,059
Ensembl chr16:96,037,001...96,121,059
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
EXP Neomycin results in increased expression of BAX mRNA
peoniflorin inhibits the reaction [Neomycin results in increased expression of BAX mRNA]
CTD PMID:29292089 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcat1 branched chain aminotransferase 1, cytosolic decreases expression EXP Neomycin results in decreased expression of BCAT1 mRNA CTD PMID:30626089 NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
EXP peoniflorin inhibits the reaction [Neomycin results in decreased expression of BCL2 mRNA]; peoniflorin inhibits the reaction [Neomycin results in decreased expression of BCL2 protein]
Neomycin results in decreased expression of BCL2 mRNA; Neomycin results in decreased expression of BCL2 protein
CTD PMID:29292089 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
affects cleavage
EXP BIX 01294 affects the reaction [Neomycin affects the cleavage of CASP3 protein]; peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP3 mRNA]; peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP3 protein modified form]
Neomycin results in increased expression of CASP3 mRNA; Neomycin results in increased expression of CASP3 protein modified form
CTD PMID:23429292 PMID:29292089 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP9 mRNA]; peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP9 protein modified form]
Neomycin results in increased expression of CASP9 mRNA; Neomycin results in increased expression of CASP9 protein modified form
CTD PMID:29292089 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Casr calcium-sensing receptor multiple interactions ISO CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Neomycin binds to and results in increased activity of CASR protein
[Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; Neomycin binds to and results in increased activity of CASR protein
CTD PMID:10231437 PMID:17537980 NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
JBrowse link
G Ccng2 cyclin G2 increases expression EXP Neomycin results in increased expression of CCNG2 mRNA CTD PMID:30626089 NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
JBrowse link
G Cd86 CD86 antigen increases expression ISO Neomycin results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdh1 cadherin 1 decreases expression EXP Neomycin results in decreased expression of CDH1 protein CTD PMID:15953529 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Clca4a chloride channel accessory 4A multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLCA4 protein CTD PMID:30545405 NCBI chr 3:144,658,247...144,680,806
Ensembl chr 3:144,658,241...144,680,806
JBrowse link
G Cldn5 claudin 5 multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein] CTD PMID:35390362 NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012
JBrowse link
G Cldn7 claudin 7 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLDN7 protein CTD PMID:30545405 NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CMBL protein CTD PMID:30545405 NCBI chr15:31,565,314...31,590,266
Ensembl chr15:31,565,535...31,590,265
JBrowse link
G Cndp2 CNDP dipeptidase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CNDP2 protein CTD PMID:30545405 NCBI chr18:84,685,590...84,703,827
Ensembl chr18:84,685,590...84,703,827
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX5A protein CTD PMID:30545405 NCBI chr 9:57,423,012...57,439,710
Ensembl chr 9:57,428,557...57,439,709
JBrowse link
G Cox6b1 cytochrome c oxidase, subunit 6B1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX6B1 protein CTD PMID:30545405 NCBI chr 7:30,316,396...30,325,539
Ensembl chr 7:30,316,286...30,325,576
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX7A2 protein CTD PMID:30545405 NCBI chr 9:79,662,523...79,667,135
Ensembl chr 9:79,662,643...79,667,160
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions EXP [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of CSF2 protein CTD PMID:31442584 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Cth cystathionine gamma lyase multiple interactions
decreases expression
EXP Plant Oils inhibits the reaction [Neomycin results in decreased expression of CTH mRNA] CTD PMID:30626089 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctsa cathepsin A multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CTSA protein CTD PMID:30545405 NCBI chr 2:164,674,792...164,682,952
Ensembl chr 2:164,674,793...164,682,952
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of CXCL9 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of CXCL9 mRNA]] CTD PMID:32068018 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA CTD PMID:36464106 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA CTD PMID:36464106 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7B1 mRNA CTD PMID:36464106 NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in decreased expression of CYP8B1 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EPCAM protein CTD PMID:30545405 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
JBrowse link
G Etfa electron transferring flavoprotein, alpha polypeptide multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ETFA protein CTD PMID:30545405 NCBI chr 9:55,361,720...55,419,528
Ensembl chr 9:55,361,792...55,419,527
JBrowse link
G Ezr ezrin multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EZR protein CTD PMID:30545405 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G Fasn fatty acid synthase multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [elemicin results in increased expression of FASN mRNA] CTD PMID:34979169 PMID:36464106 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fgf15 fibroblast growth factor 15 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of FGF15 mRNA CTD PMID:24657338 NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases expression
EXP Plant Oils inhibits the reaction [Neomycin results in increased expression of FOXO1 mRNA] CTD PMID:30626089 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma increases expression
multiple interactions
EXP Neomycin results in increased expression of GADD45G mRNA
Plant Oils inhibits the reaction [Neomycin results in increased expression of GADD45G mRNA]
CTD PMID:30626089 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gfpt2 glutamine fructose-6-phosphate transaminase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GFPT2 protein CTD PMID:30545405 NCBI chr11:49,684,981...49,729,448
Ensembl chr11:49,685,005...49,729,440
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GIPC2 protein CTD PMID:30545405 NCBI chr 3:151,799,476...151,871,537
Ensembl chr 3:151,799,170...151,871,867
JBrowse link
G Gng12 guanine nucleotide binding protein (G protein), gamma 12 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GNG12 protein CTD PMID:30545405 NCBI chr 6:66,873,381...66,998,345
Ensembl chr 6:66,873,381...66,998,334
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [elemicin results in increased activity of GPT protein] CTD PMID:34979169 PMID:36464106 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 decreases expression EXP Neomycin results in decreased expression of GPT2 mRNA CTD PMID:30626089 NCBI chr 8:86,219,090...86,255,531
Ensembl chr 8:86,219,205...86,254,189
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GPX1 protein CTD PMID:30545405 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTM2 mRNA CTD PMID:30545405 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G H2-DMb1 histocompatibility 2, class II, locus Mb1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RT1-DMB protein CTD PMID:30545405 NCBI chr17:34,372,165...34,379,203
Ensembl chr17:34,372,046...34,379,204
JBrowse link
G Hexb hexosaminidase B multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of HEXB protein CTD PMID:30545405 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA CTD PMID:36464106 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of HMOX1 protein] CTD PMID:36535435 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HNRNPH2 protein CTD PMID:30545405 NCBI chr  X:133,501,928...133,507,809
Ensembl chr  X:133,501,928...133,507,809
JBrowse link
G Hp haptoglobin multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HP protein CTD PMID:30545405 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions ISO Neomycin inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein] CTD PMID:16178011 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Htr4 5 hydroxytryptamine (serotonin) receptor 4 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide results in increased expression of HTR4 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in increased expression of HTR4 mRNA CTD PMID:36535435 NCBI chr18:62,456,618...62,636,098
Ensembl chr18:62,457,275...62,629,648
JBrowse link
G Il18 interleukin 18 multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of IL1B protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of IL1B protein]] CTD PMID:32068018 PMID:35390362 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein] CTD PMID:31442584 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inhba inhibin beta-A increases expression EXP Neomycin results in increased expression of INHBA mRNA CTD PMID:30626089 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
JBrowse link
G Ins2 insulin II multiple interactions ISO Neomycin inhibits the reaction [INS protein results in increased uptake of cobaltous chloride] CTD PMID:14622148 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Irs2 insulin receptor substrate 2 increases expression EXP Neomycin results in increased expression of IRS2 mRNA CTD PMID:30626089 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO 3,9-bis((ethylthio)methyl)-K-252a inhibits the reaction [Neomycin results in increased expression of JUN protein modified form] CTD PMID:10627579 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) increases expression EXP Neomycin results in increased expression of KLF2 mRNA CTD PMID:30626089 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Kng2 kininogen 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAP1 protein CTD PMID:30545405 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Krt16 keratin 16 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of KRT16 protein CTD PMID:30545405 NCBI chr11:100,136,917...100,139,728
Ensembl chr11:100,136,917...100,139,728
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole co-treated with elemicin] results in increased expression of LEP mRNA CTD PMID:34979169 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lpin1 lipin 1 multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA CTD PMID:36464106 NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
JBrowse link
G Lyz2 lysozyme 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of LYZ2 protein CTD PMID:30545405 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein
Neomycin results in increased expression of MAPK1 protein modified form
peoniflorin inhibits the reaction [Neomycin results in increased expression of MAPK1 protein modified form]
CTD PMID:17537980 PMID:29292089 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAPK3 protein
peoniflorin inhibits the reaction [Neomycin results in increased expression of MAPK3 protein modified form]
CTD PMID:17537980 PMID:29292089 PMID:30545405 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mlxip MLX interacting protein multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [elemicin results in increased expression of MLXIP mRNA] CTD PMID:34979169 NCBI chr 5:123,532,438...123,595,998
Ensembl chr 5:123,532,861...123,595,995
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase decreases expression
multiple interactions
EXP Neomycin results in decreased expression of MTHFD2 mRNA
Plant Oils inhibits the reaction [Neomycin results in decreased expression of MTHFD2 mRNA]
CTD PMID:30626089 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein] CTD PMID:35390362 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Myh14 myosin, heavy polypeptide 14 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MYH14 protein CTD PMID:30545405 NCBI chr 7:44,255,227...44,320,296
Ensembl chr 7:44,255,227...44,320,267
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFA13 protein CTD PMID:30545405 NCBI chr 8:70,346,813...70,355,208
Ensembl chr 8:70,346,830...70,355,208
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFAB1 protein CTD PMID:30545405 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109
JBrowse link
G Nog noggin increases expression EXP Neomycin results in increased expression of NOG mRNA CTD PMID:30626089 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of NOS2 mRNA]] CTD PMID:32068018 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of NPC1L1 mRNA CTD PMID:24657338 NCBI chr11:6,161,011...6,180,245
Ensembl chr11:6,161,013...6,180,143
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of NPC2 protein CTD PMID:30545405 NCBI chr12:84,801,333...84,819,886
Ensembl chr12:84,801,336...84,819,926
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of NR5A2 mRNA CTD PMID:24657338 NCBI chr 1:136,770,300...136,888,186
Ensembl chr 1:136,770,309...136,888,186
JBrowse link
G Ocln occludin multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein] CTD PMID:35390362 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Pdxk pyridoxal (pyridoxine, vitamin B6) kinase multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PDXK protein CTD PMID:30545405 NCBI chr10:78,272,581...78,300,782
Ensembl chr10:78,272,578...78,300,809
JBrowse link
G Pfn1 profilin 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PFN1 protein CTD PMID:30545405 NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein CTD PMID:30545405 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
JBrowse link
G Pmm2 phosphomannomutase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PMM2 protein CTD PMID:30545405 NCBI chr16:8,455,467...8,475,472
Ensembl chr16:8,455,538...8,480,331
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CA protein CTD PMID:30545405 NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CB protein CTD PMID:30545405 NCBI chr 5:32,616,192...32,651,057
Ensembl chr 5:32,616,187...32,674,777
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CC protein CTD PMID:30545405 NCBI chr 5:122,296,338...122,313,336
Ensembl chr 5:122,296,341...122,313,336
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions
decreases expression
EXP Plant Oils inhibits the reaction [Neomycin results in decreased expression of PSAT1 mRNA] CTD PMID:30626089 NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
JBrowse link
G Psma3 proteasome subunit alpha 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein CTD PMID:30545405 NCBI chr12:71,016,082...71,042,651
Ensembl chr12:71,021,395...71,043,121
JBrowse link
G Psph phosphoserine phosphatase decreases expression
multiple interactions
EXP Neomycin results in decreased expression of PSPH mRNA
Plant Oils inhibits the reaction [Neomycin results in decreased expression of PSPH mRNA]
CTD PMID:30626089 NCBI chr 5:129,842,622...129,864,318
Ensembl chr 5:129,842,622...129,864,513
JBrowse link
G Ralb v-ral simian leukemia viral oncogene B multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RALB protein CTD PMID:30545405 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524
JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA protein] CTD PMID:35390362 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rida reactive intermediate imine deaminase A homolog multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RIDA protein CTD PMID:30545405 NCBI chr15:34,484,168...34,495,392
Ensembl chr15:34,484,167...34,495,401
JBrowse link
G Rpl30 ribosomal protein L30 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPL30 protein CTD PMID:30545405 NCBI chr15:34,440,649...34,443,405
Ensembl chr15:34,440,651...34,443,786
JBrowse link
G Rpn2 ribophorin II multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPN2 protein CTD PMID:30545405 NCBI chr 2:157,121,018...157,168,238
Ensembl chr 2:157,120,937...157,168,239
JBrowse link
G Rps23 ribosomal protein S23 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS23 protein CTD PMID:30545405 NCBI chr13:91,071,241...91,072,851
Ensembl chr13:91,071,077...91,073,069
JBrowse link
G Rps27l ribosomal protein S27-like multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS27L protein CTD PMID:30545405 NCBI chr 9:66,851,906...66,856,804
Ensembl chr 9:66,853,368...66,856,798
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 affects phosphorylation EXP Neomycin affects the phosphorylation of RPS6KB1 protein CTD PMID:16537399 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G S100a10 S100 calcium binding protein A10 (calpactin) multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A10 protein CTD PMID:30545405 NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A11 protein CTD PMID:30545405 NCBI chr 3:93,427,803...93,433,595
Ensembl chr 3:93,427,795...93,433,594
JBrowse link
G Scarb2 scavenger receptor class B, member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of SCARB2 protein CTD PMID:30545405 NCBI chr 5:92,589,170...92,653,516
Ensembl chr 5:92,589,173...92,654,692
JBrowse link
G Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SERPINB6 protein CTD PMID:30545405 NCBI chr13:34,101,901...34,186,777
Ensembl chr13:34,101,901...34,186,777
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) decreases expression
multiple interactions
EXP
ISO
Neomycin results in decreased expression of SHMT2 mRNA
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SHMT2 protein
CTD PMID:30545405 PMID:30626089 NCBI chr10:127,352,992...127,358,313
Ensembl chr10:127,352,992...127,358,313
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of SLC10A1 mRNA CTD PMID:24657338 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SLC22A7 mRNA CTD PMID:36464106 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link
G Slc3a1 solute carrier family 3, member 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SLC3A1 protein CTD PMID:30545405 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
JBrowse link
G Slc51b solute carrier family 51, beta subunit multiple interactions EXP [Cephalothin co-treated with Neomycin] results in decreased expression of SLC51B mRNA CTD PMID:24657338 NCBI chr 9:65,320,035...65,330,055
Ensembl chr 9:65,319,996...65,330,237
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of SLCO1B2 mRNA CTD PMID:24657338 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Smad6 SMAD family member 6 increases expression EXP Neomycin results in increased expression of SMAD6 mRNA CTD PMID:30626089 NCBI chr 9:63,860,358...63,929,374
Ensembl chr 9:63,860,358...63,929,341
JBrowse link
G Smad9 SMAD family member 9 increases expression EXP Neomycin results in increased expression of SMAD9 mRNA CTD PMID:30626089 NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2, neutral multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SMPD2 protein CTD PMID:30545405 NCBI chr10:41,363,168...41,366,410
Ensembl chr10:41,361,638...41,366,365
JBrowse link
G Sqle squalene epoxidase multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SQLE mRNA CTD PMID:36464106 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of SQSTM1 protein] CTD PMID:36535435 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF2 mRNA CTD PMID:36464106 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Sst somatostatin multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide results in increased expression of SST mRNA]; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in increased expression of SST mRNA CTD PMID:36535435 NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
JBrowse link
G Sstr2 somatostatin receptor 2 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide results in increased expression of SSTR2 mRNA] CTD PMID:36535435 NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TARS1 protein CTD PMID:30545405 NCBI chr15:11,383,749...11,399,744
Ensembl chr15:11,382,387...11,399,751
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions
increases expression
EXP Plant Oils inhibits the reaction [Neomycin results in increased expression of TGFB2 mRNA] CTD PMID:30626089 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein] CTD PMID:35390362 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]; TLR4 gene mutant form results in decreased susceptibility to [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] CTD PMID:35390362 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TM9SF2 protein CTD PMID:30545405 NCBI chr14:122,342,290...122,397,015
Ensembl chr14:122,344,450...122,397,016
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TMED10 protein CTD PMID:30545405 NCBI chr12:85,387,388...85,421,491
Ensembl chr12:85,387,388...85,421,621
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of TNF protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of TNF protein]]; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein] CTD PMID:31442584 PMID:32068018 PMID:35390362 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Traf6 TNF receptor-associated factor 6 multiple interactions EXP [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein] CTD PMID:35390362 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014
JBrowse link
G Tubal3 tubulin, alpha-like 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TUBAL3 protein CTD PMID:30545405 NCBI chr13:3,974,695...3,985,277
Ensembl chr13:3,968,274...3,985,277
JBrowse link
G Twf1 twinfilin actin binding protein 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TWF1 protein CTD PMID:30545405 NCBI chr15:94,475,829...94,487,727
Ensembl chr15:94,475,832...94,487,770
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of TXN1 protein] CTD PMID:36535435 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txndc5 thioredoxin domain containing 5 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TXNDC5 protein CTD PMID:30545405 NCBI chr13:38,684,242...38,712,800
Ensembl chr13:38,684,055...38,712,800
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRC1 protein CTD PMID:30545405 NCBI chr 9:108,765,716...108,778,709
Ensembl chr 9:108,765,701...108,778,691
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRFS1 protein CTD PMID:30545405 NCBI chr13:30,724,295...30,729,299
Ensembl chr13:30,724,291...30,729,345
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRH protein CTD PMID:30545405 NCBI chr 4:115,924,162...115,932,267
Ensembl chr 4:115,924,162...115,932,268
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor multiple interactions EXP [Cephalothin co-treated with Neomycin] results in increased expression of VDR mRNA CTD PMID:24657338 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
notoginsenoside R1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 increases transport ISO ABCB11 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
increases expression
ISO
EXP
NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]
notoginsenoside R1 results in increased expression of ABCB1A mRNA
CTD PMID:25472953 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases transport ISO ABCC1 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases transport ISO ABCC2 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases transport ISO ABCG2 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
EXP notoginsenoside R1 results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of AKT1 protein]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased phosphorylation of AKT1 protein]
CTD PMID:33689844 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Apoe apolipoprotein E multiple interactions EXP notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in decreased abundance of Glutathione]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in decreased expression of MIR20A mRNA]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased abundance of Cholesterol]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased abundance of Triglycerides]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IFNG protein]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL2 protein]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR126A mRNA]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR21A mRNA]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of TNF protein] CTD PMID:24933211 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP
ISO
notoginsenoside R1 inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of APP protein modified form]
notoginsenoside R1 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased cleavage of CASP3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK9 protein]
CTD PMID:24975829 PMID:25714973 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; Cyclosporine inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; notoginsenoside R1 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]
notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased expression of BAX protein]
CTD PMID:19224577 PMID:24975829 PMID:25305180 PMID:33689844 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
increases expression
EXP
ISO
notoginsenoside R1 inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]
notoginsenoside R1 results in increased expression of BCL2
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein]
CTD PMID:19224577 PMID:20023602 PMID:23170834 PMID:24975829 PMID:25305180 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bglap bone gamma carboxyglutamate protein multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of BGLAP mRNA] CTD PMID:26362186 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of BID protein modified form] CTD PMID:23170834 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]]; Cyclosporine inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein modified form]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased cleavage of CASP3 protein]; notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]
CTD PMID:23170834 PMID:24437944 PMID:24720662 PMID:24975829 PMID:25305180 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP8 protein] CTD PMID:23170834 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP9 protein] CTD PMID:23170834 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:25503068 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:23170834 PMID:25472953 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Chat choline acetyltransferase increases expression EXP notoginsenoside R1 results in increased expression of CHAT CTD PMID:25714973 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions EXP notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of CHUK protein modified form] CTD PMID:25472953 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO notoginsenoside R1 results in decreased activity of CYP1A2 protein CTD PMID:25834921 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 increases expression EXP notoginsenoside R1 results in increased expression of CYP3A11 mRNA CTD PMID:25472953 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
increases expression
ISO
EXP
notoginsenoside R1 results in increased phosphorylation of and results in increased activity of ESR1 protein
notoginsenoside R1 results in increased expression of ESR1; notoginsenoside R1 results in increased expression of ESR1 mRNA; notoginsenoside R1 results in increased expression of ESR1 protein
[1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole results in decreased activity of ESR1 protein] which results in decreased susceptibility to notoginsenoside R1; [notoginsenoside R1 co-treated with Lipopolysaccharides] results in increased expression of ESR1 protein; fulvestrant inhibits the reaction [[notoginsenoside R1 co-treated with Lipopolysaccharides] results in increased expression of ESR1 protein]
CTD PMID:23170834 PMID:24720662 PMID:25738436 PMID:26362186 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) increases expression ISO notoginsenoside R1 results in increased expression of ESR2 CTD PMID:24720662 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G F3 coagulation factor III multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of F3 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] CTD PMID:9102164 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of FAS mRNA] CTD PMID:23170834 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased secretion of FN1 protein]; notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased expression of FN1 mRNA]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of FN1 mRNA] CTD PMID:16632126 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide results in increased expression of GCLC protein] CTD PMID:24437944 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) multiple interactions ISO [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to notoginsenoside R1 CTD PMID:19224577 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions ISO [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to notoginsenoside R1 CTD PMID:19224577 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression
EXP
ISO
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]; wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]
notoginsenoside R1 results in increased expression of GSK3B protein modified form
CTD PMID:23170834 PMID:24720662 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 mRNA; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 protein
notoginsenoside R1 results in increased expression of HMOX1; notoginsenoside R1 results in increased expression of HMOX1 protein
Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]
CTD PMID:24437944 PMID:24720662 PMID:25422538 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] CTD PMID:23170834 PMID:25472953 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ide insulin degrading enzyme multiple interactions
increases expression
EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [notoginsenoside R1 results in increased expression of IDE] CTD PMID:25714973 NCBI chr19:37,246,140...37,341,664
Ensembl chr19:37,246,142...37,340,010
JBrowse link
G Ifng interferon gamma multiple interactions EXP notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IFNG protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein] CTD PMID:23170834 PMID:24933211 PMID:25472953 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions EXP notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IKBKB protein modified form] CTD PMID:25472953 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il10 interleukin 10 multiple interactions EXP notoginsenoside R1 promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein] CTD PMID:23170834 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il15 interleukin 15 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL15 mRNA] CTD PMID:25472953 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1A mRNA] CTD PMID:25472953 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:23170834 PMID:25472953 PMID:25738436 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 multiple interactions EXP notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL2 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL2 mRNA] CTD PMID:24933211 PMID:25472953 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:17655881 PMID:23170834 PMID:24933211 PMID:25472953 PMID:25738436 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ilk integrin linked kinase multiple interactions ISO notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] CTD PMID:25503068 NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132
JBrowse link
G Itga3 integrin alpha 3 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGA3 protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein] CTD PMID:25503068 NCBI chr11:94,935,301...94,967,637
Ensembl chr11:94,935,300...94,967,627
JBrowse link
G Itgam integrin alpha M multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] CTD PMID:17655881 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions EXP notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGB1 protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein] CTD PMID:25503068 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Itgb2 integrin beta 2 decreases expression
multiple interactions
EXP
ISO
notoginsenoside R1 results in decreased expression of ITGB2 protein
notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGB2 protein]
CTD PMID:17655881 PMID:18176958 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]
fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK1 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK1 protein]
CTD PMID:16458614 PMID:16632126 PMID:24437944 PMID:24975829 PMID:25004876 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK3 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK3 protein]
notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:16458614 PMID:16632126 PMID:24437944 PMID:24975829 PMID:25004876 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein] CTD PMID:24975829 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK9 protein] CTD PMID:24975829 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mir126a microRNA 126a multiple interactions EXP notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR126A mRNA] CTD PMID:24933211 NCBI chr 2:26,481,369...26,481,441
Ensembl chr 2:26,481,369...26,481,441
JBrowse link
G Mir20a microRNA 20a multiple interactions EXP notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in decreased expression of MIR20A mRNA] CTD PMID:24933211 NCBI chr14:115,281,589...115,281,695
Ensembl chr14:115,281,589...115,281,695
JBrowse link
G Mir21a microRNA 21a multiple interactions EXP notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR21A mRNA] CTD PMID:24933211 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases expression
EXP
ISO
notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
notoginsenoside R1 results in decreased expression of MPO protein
CTD PMID:20023602 PMID:25472953 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
multiple interactions
EXP
ISO
notoginsenoside R1 affects the localization of NFE2L2 protein
NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased expression of and affects the localization of NFE2L2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 results in increased expression of and affects the localization of NFE2L2 protein]; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] affects the localization of NFE2L2 protein; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased expression of and affects the localization of NFE2L2 protein]; notoginsenoside R1 results in increased expression of and affects the localization of NFE2L2 protein
CTD PMID:24437944 PMID:24720662 PMID:25422538 PMID:33689844 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO
EXP
notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; notoginsenoside R1 promotes the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]; wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]]
CTD PMID:9102164 PMID:23170834 PMID:25472953 PMID:25738436 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP
ISO
notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
[notoginsenoside R1 results in increased phosphorylation of and results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide; notoginsenoside R1 results in increased phosphorylation of and results in increased activity of NOS2 protein
CTD PMID:23170834 PMID:25472953 PMID:26045775 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NOS3 protein] CTD PMID:23170834 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide results in increased expression of NQO1 protein] CTD PMID:24437944 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
increases response to substance
ISO
EXP
notoginsenoside R1 binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of UGT1A1 mRNA]
notoginsenoside R1 results in increased activity of NR1I2 protein
NR1I2 protein results in increased susceptibility to notoginsenoside R1
CTD PMID:25472953 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein modified form] CTD PMID:23170834 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Plat plasminogen activator, tissue increases expression
multiple interactions
ISO notoginsenoside R1 results in increased expression of PLAT mRNA; notoginsenoside R1 results in increased expression of PLAT protein
notoginsenoside R1 results in increased expression of [PLAT protein binds to SERPINE1 protein]
CTD PMID:8018658 PMID:9220151 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO notoginsenoside R1 results in increased expression of PLAU mRNA; notoginsenoside R1 results in increased expression of PLAU protein CTD PMID:9220151 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression
EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [notoginsenoside R1 results in increased expression of PPARG] CTD PMID:25714973 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein] CTD PMID:25305180 NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336
JBrowse link
G Psen1 presenilin 1 multiple interactions EXP notoginsenoside R1 inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of APP protein modified form] CTD PMID:25714973 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:25472953 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP
ISO
notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein modified form]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein modified form]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of RELA protein]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of RELA protein]
CTD PMID:23170834 PMID:25472953 PMID:25738436 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of ROCK1 protein] CTD PMID:25305180 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045
JBrowse link
G Runx2 runt related transcription factor 2 increases expression
multiple interactions
ISO notoginsenoside R1 results in increased expression of RUNX2 mRNA
fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of RUNX2 mRNA]
CTD PMID:26362186 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sele selectin, endothelial cell decreases expression EXP notoginsenoside R1 results in decreased expression of SELE protein CTD PMID:18176958 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions
decreases activity
ISO
EXP
notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of SERPINE1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; notoginsenoside R1 results in increased expression of [PLAT protein binds to SERPINE1 protein]
notoginsenoside R1 results in decreased activity of SERPINE1 protein
CTD PMID:8018658 PMID:9102164 PMID:16458614 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions ISO SLCO1B2 protein binds to and results in increased transport of notoginsenoside R1
SLCO1B3 protein binds to and results in increased transport of notoginsenoside R1
CTD PMID:25297453 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Sp7 Sp7 transcription factor 7 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of SP7 mRNA] CTD PMID:26362186 NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of SPARC mRNA] CTD PMID:26362186 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
JBrowse link
G Sqstm1 sequestosome 1 affects localization
multiple interactions
EXP notoginsenoside R1 affects the localization of SQSTM1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 affects the localization of SQSTM1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate affects the localization of SQSTM1 protein]]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate affects the localization of SQSTM1 protein]
CTD PMID:33689844 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of SERPINE1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
notoginsenoside R1 results in decreased expression of TNF
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
CTD PMID:9102164 PMID:16458614 PMID:16632126 PMID:20023602 PMID:23170834 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A mRNA] CTD PMID:23170834 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TRP53 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TRP53 protein] CTD PMID:23170834 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases expression
multiple interactions
ISO
EXP
notoginsenoside R1 results in increased expression of UGT1A1 mRNA
NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of UGT1A1 mRNA]
CTD PMID:25472953 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein] CTD PMID:23170834 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
oleuropein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased activity of ACE protein] CTD PMID:26056852 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in increased expression of ACTA2 protein] CTD PMID:36774383 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in decreased secretion of ADIPOQ protein] CTD PMID:27019295 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in decreased phosphorylation of AKT1 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein] CTD PMID:34126350 PMID:36774383 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO
EXP
oleuropein inhibits the reaction [Acrolein results in increased expression of BAX mRNA]; oleuropein inhibits the reaction [Acrolein results in increased expression of BAX protein]
oleuropein inhibits the reaction [Rotenone results in increased expression of BAX protein]
CTD PMID:29414845 PMID:36774383 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO
EXP
oleuropein inhibits the reaction [Acrolein results in decreased expression of BCL2 mRNA]; oleuropein inhibits the reaction [Acrolein results in decreased expression of BCL2 protein]; oleuropein inhibits the reaction [decamethrin results in decreased expression of BCL2 protein]
oleuropein affects the reaction [Rotenone results in decreased expression of BCL2 protein]
CTD PMID:28595958 PMID:29414845 PMID:36774383 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions EXP oleuropein affects the reaction [Rotenone results in decreased expression of BDNF protein] CTD PMID:36774383 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Casp3 caspase 3 multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in increased cleavage of CASP3 protein] CTD PMID:36774383 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase increases activity
multiple interactions
ISO
EXP
oleuropein results in increased activity of CAT protein
oleuropein inhibits the reaction [Rotenone results in decreased activity of CAT protein]
oleuropein inhibits the reaction [decamethrin results in decreased activity of CAT protein]
CTD PMID:18823963 PMID:28595958 PMID:36774383 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in decreased phosphorylation of CREB1 protein] CTD PMID:36774383 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP oleuropein inhibits the reaction [TNF protein results in increased export of CSF1R protein] CTD PMID:34126350 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO oleuropein results in decreased activity of CYP19A1 protein CTD PMID:17910019 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO oleuropein inhibits the reaction [Acrolein results in increased expression of DDIT3 protein] CTD PMID:29414845 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of FASN protein] CTD PMID:27019295 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased activity of GPT protein]; oleuropein inhibits the reaction [decamethrin results in increased expression of GPT protein]; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein] CTD PMID:26056852 PMID:27019295 PMID:28595958 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:36774383 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO oleuropein inhibits the reaction [Acrolein results in increased expression of HSPA5 protein] CTD PMID:29414845 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] CTD PMID:12615669 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il6 interleukin 6 multiple interactions EXP oleuropein inhibits the reaction [TNF protein results in increased export of IL6 protein] CTD PMID:34126350 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein] CTD PMID:26056852 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:34126350 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:34126350 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein] CTD PMID:22595400 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO oleuropein inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein] CTD PMID:17223128 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of NTRK2 protein] CTD PMID:36774383 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
JBrowse link
G Pnlip pancreatic lipase multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased activity of PNLIP protein] CTD PMID:26056852 NCBI chr19:58,658,797...58,670,231
Ensembl chr19:58,640,930...58,670,220
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of PPARG protein] CTD PMID:27019295 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO oleuropein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]
oleuropein inhibits the reaction [decamethrin results in increased expression of PTGS2 protein]
CTD PMID:22595400 PMID:28595958 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein] CTD PMID:22595400 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein] CTD PMID:12615669 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of SREBF1 protein] CTD PMID:27019295 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP oleuropein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:36774383 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
oleuropein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
oleuropein inhibits the reaction [TNF protein results in increased export of CSF1R protein]; oleuropein inhibits the reaction [TNF protein results in increased export of IL6 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:12615669 PMID:34126350 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnnt1 troponin T1, skeletal, slow multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of TNNT1 protein] CTD PMID:26056852 NCBI chr 7:4,507,568...4,518,974
Ensembl chr 7:4,507,569...4,519,381
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO oleuropein inhibits the reaction [decamethrin results in increased expression of TP53 protein] CTD PMID:28595958 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]; oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:12615669 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
pelargonidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
pelargonidin 3-O-beta-D-glucoside chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
petunidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp3 aquaporin 3 multiple interactions ISO [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
phlorizin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase decreases expression EXP Phlorhizin results in decreased expression of ABAT mRNA CTD PMID:22538082 NCBI chr16:8,331,293...8,439,432
Ensembl chr16:8,331,293...8,439,432
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression EXP Phlorhizin results in increased expression of ACAA1 mRNA CTD PMID:22538082 NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression EXP Phlorhizin results in decreased expression of ACAA2 mRNA CTD PMID:22538082 NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279
JBrowse link
G Acad8 acyl-Coenzyme A dehydrogenase family, member 8 decreases expression EXP Phlorhizin results in decreased expression of ACAD8 mRNA CTD PMID:22538082 NCBI chr 9:26,885,434...26,910,872
Ensembl chr 9:26,885,431...26,910,862
JBrowse link
G Acad9 acyl-Coenzyme A dehydrogenase family, member 9 decreases expression EXP Phlorhizin results in decreased expression of ACAD9 mRNA CTD PMID:22538082 NCBI chr 3:36,120,128...36,147,006
Ensembl chr 3:36,120,128...36,147,002
JBrowse link
G Acadl acyl-Coenzyme A dehydrogenase, long-chain decreases expression EXP Phlorhizin results in decreased expression of ACADL mRNA CTD PMID:22538082 NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain decreases expression EXP Phlorhizin results in decreased expression of ACADM mRNA CTD PMID:22538082 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 decreases expression EXP Phlorhizin results in decreased expression of ACAT1 mRNA CTD PMID:22538082 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
JBrowse link
G Aco1 aconitase 1 decreases expression EXP Phlorhizin results in decreased expression of ACO1 mRNA CTD PMID:22538082 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl decreases expression EXP Phlorhizin results in decreased expression of ACOX1 mRNA CTD PMID:22538082 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acox2 acyl-Coenzyme A oxidase 2, branched chain decreases expression EXP Phlorhizin results in decreased expression of ACOX2 mRNA CTD PMID:22538082 NCBI chr14:14,210,406...14,244,262
Ensembl chr14:14,210,420...14,244,262
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP Phlorhizin results in decreased expression of ACSL1 mRNA CTD PMID:22538082 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
JBrowse link
G Actb actin, beta increases expression EXP Phlorhizin results in increased expression of ACTB mRNA CTD PMID:22538082 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression EXP Phlorhizin results in decreased expression of ADH5 mRNA CTD PMID:22538082 NCBI chr 3:138,142,961...138,161,260
Ensembl chr 3:138,148,854...138,161,260
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP Phlorhizin results in decreased expression of ADHFE1 mRNA CTD PMID:22538082 NCBI chr 1:9,618,173...9,648,195
Ensembl chr 1:9,618,173...9,650,898
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA CTD PMID:32408695 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 decreases expression EXP Phlorhizin results in decreased expression of AKR1A1 mRNA CTD PMID:22538082 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
JBrowse link
G Akr7a5 aldo-keto reductase family 7, member A5 increases expression EXP Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737
JBrowse link
G Alb albumin multiple interactions ISO Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein] CTD PMID:16313995 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 decreases expression EXP Phlorhizin results in decreased expression of ALDH1A7 mRNA CTD PMID:22538082 NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial decreases expression
increases expression
EXP Phlorhizin results in decreased expression of ALDH2 mRNA
Phlorhizin results in increased expression of ALDH2 mRNA
CTD PMID:22538082 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 decreases expression EXP Phlorhizin results in decreased expression of ALDH3A2 mRNA CTD PMID:22538082 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression EXP Phlorhizin results in decreased expression of ALDH4A1 mRNA CTD PMID:22538082 NCBI chr 4:139,348,404...139,377,002
Ensembl chr 4:139,350,177...139,377,001
JBrowse link
G Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 decreases expression EXP Phlorhizin results in decreased expression of ALDH6A1 mRNA CTD PMID:22538082 NCBI chr12:84,477,491...84,497,798
Ensembl chr12:84,477,491...84,497,778
JBrowse link
G Aldh7a1 aldehyde dehydrogenase family 7, member A1 decreases expression EXP Phlorhizin results in decreased expression of ALDH7A1 mRNA CTD PMID:22538082 NCBI chr18:56,657,794...56,706,112
Ensembl chr18:56,642,759...56,706,023
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 decreases expression EXP Phlorhizin results in decreased expression of ANAPC2 mRNA CTD PMID:22538082 NCBI chr 2:25,162,469...25,175,928
Ensembl chr 2:25,162,490...25,175,927
JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 decreases expression EXP Phlorhizin results in decreased expression of ANAPC5 mRNA CTD PMID:22538082 NCBI chr 5:122,925,522...122,960,402
Ensembl chr 5:122,925,522...122,959,402
JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression EXP Phlorhizin results in decreased expression of AOX1 mRNA CTD PMID:22538082 NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572
JBrowse link
G Aox3 aldehyde oxidase 3 decreases expression EXP Phlorhizin results in decreased expression of AOX3 mRNA CTD PMID:22538082 NCBI chr 1:58,152,294...58,241,380
Ensembl chr 1:58,152,289...58,239,857
JBrowse link
G Aph1b aph1 homolog B, gamma secretase subunit increases expression EXP Phlorhizin results in increased expression of APH1B mRNA CTD PMID:22538082 NCBI chr 9:66,682,484...66,704,671
Ensembl chr 9:66,682,484...66,702,772
JBrowse link
G App amyloid beta precursor protein decreases expression EXP Phlorhizin results in decreased expression of APP mRNA CTD PMID:22538082 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Atf3 activating transcription factor 3 decreases expression EXP Phlorhizin results in decreased expression of ATF3 mRNA CTD PMID:16123366 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 increases expression EXP Phlorhizin results in increased expression of ATP2A2 mRNA CTD PMID:16123366 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression EXP Phlorhizin results in decreased expression of ATP5F1A mRNA CTD PMID:22538082 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma increases expression EXP Phlorhizin results in increased expression of ATP5F1C mRNA CTD PMID:22538082 NCBI chr 2:10,060,841...10,085,321
Ensembl chr 2:10,060,827...10,085,321
JBrowse link
G Auh AU RNA binding protein/enoyl-coenzyme A hydratase decreases expression EXP Phlorhizin results in decreased expression of AUH mRNA CTD PMID:22538082 NCBI chr13:52,989,155...53,083,742
Ensembl chr13:52,989,155...53,083,717
JBrowse link
G B2m beta-2 microglobulin increases expression EXP Phlorhizin results in increased expression of B2M mRNA CTD PMID:22538082 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein] CTD PMID:32408695 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bag1 BCL2-associated athanogene 1 decreases expression EXP Phlorhizin results in decreased expression of BAG1 mRNA CTD PMID:22538082 NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294
JBrowse link
G Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide decreases expression EXP Phlorhizin results in decreased expression of BCKDHB mRNA CTD PMID:22538082 NCBI chr 9:83,807,190...84,006,293
Ensembl chr 9:83,807,198...84,006,293
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions EXP [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein] CTD PMID:32408695 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases expression EXP Phlorhizin results in increased expression of BIRC6 mRNA CTD PMID:22538082 NCBI chr17:74,835,247...75,010,351
Ensembl chr17:74,835,290...75,010,351
JBrowse link
G Cat catalase increases expression EXP Phlorhizin results in increased expression of CAT mRNA CTD PMID:22538082 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA CTD PMID:32408695 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression EXP Phlorhizin results in decreased expression of CCT7 mRNA CTD PMID:22538082 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] CTD PMID:18715473 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Clybl citrate lyase beta like decreases expression EXP Phlorhizin results in decreased expression of CLYBL mRNA CTD PMID:22538082 NCBI chr14:122,408,289...122,639,646
Ensembl chr14:122,419,116...122,639,646
JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 decreases expression EXP Phlorhizin results in decreased expression of COX15 mRNA CTD PMID:22538082 NCBI chr19:43,721,693...43,741,439
Ensembl chr19:43,721,693...43,741,439
JBrowse link
G Cox17 cytochrome c oxidase assembly protein 17, copper chaperone decreases expression EXP Phlorhizin results in decreased expression of COX17 mRNA CTD PMID:22538082 NCBI chr16:38,167,332...38,173,125
Ensembl chr16:38,167,353...38,182,659
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C increases expression EXP Phlorhizin results in increased expression of COX7C mRNA CTD PMID:22538082 NCBI chr13:86,192,917...86,194,914
Ensembl chr13:86,192,935...86,195,023
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A decreases expression EXP Phlorhizin results in decreased expression of COX8A mRNA CTD PMID:22538082 NCBI chr19:7,192,523...7,194,981
Ensembl chr19:7,192,518...7,194,981
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver decreases expression EXP Phlorhizin results in decreased expression of CPT1A mRNA CTD PMID:16123366 PMID:22538082 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression EXP Phlorhizin results in decreased expression of CPT2 mRNA CTD PMID:22538082 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
JBrowse link
G Crebbp CREB binding protein decreases expression EXP Phlorhizin results in decreased expression of CREBBP mRNA CTD PMID:22538082 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
JBrowse link
G Cs citrate synthase decreases expression EXP Phlorhizin results in decreased expression of CS mRNA CTD PMID:22538082 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348
JBrowse link
G Cul1 cullin 1 decreases expression EXP Phlorhizin results in decreased expression of CUL1 mRNA CTD PMID:22538082 NCBI chr 6:47,430,516...47,503,078
Ensembl chr 6:47,430,332...47,503,073
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP Phlorhizin results in decreased expression of CYB5R3 mRNA CTD PMID:22538082 NCBI chr15:83,037,696...83,060,641
Ensembl chr15:83,037,695...83,056,793
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP Phlorhizin results in decreased expression of CYP1A2 mRNA CTD PMID:22538082 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases expression EXP Phlorhizin results in decreased expression of CYP2B6 mRNA CTD PMID:22538082 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2d13 cytochrome P450, family 2, subfamily d, polypeptide 13 decreases expression EXP Phlorhizin results in decreased expression of CYP2D13 mRNA CTD PMID:22538082 NCBI chr15:82,520,951...82,526,246
Ensembl chr15:82,520,388...82,526,247
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases expression EXP Phlorhizin results in increased expression of CYP2D6 mRNA CTD PMID:22538082 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2j5 cytochrome P450, family 2, subfamily j, polypeptide 5 decreases expression EXP Phlorhizin results in decreased expression of CYP2J5 mRNA CTD PMID:22538082 NCBI chr 4:96,517,010...96,552,391
Ensembl chr 4:96,517,010...96,552,391
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases expression
increases expression
EXP Phlorhizin results in decreased expression of CYP3A7 mRNA
Phlorhizin results in increased expression of CYP3A7 mRNA
CTD PMID:22538082 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 increases expression EXP Phlorhizin results in increased expression of CYP4A11 mRNA CTD PMID:22538082 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 decreases expression EXP Phlorhizin results in decreased expression of CYP4F12 mRNA CTD PMID:22538082 NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 decreases expression EXP Phlorhizin results in decreased expression of DHRS4 mRNA CTD PMID:22538082 NCBI chr14:55,715,880...55,727,797
Ensembl chr14:55,716,215...55,727,797
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP Phlorhizin results in decreased expression of DLD mRNA CTD PMID:22538082 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 decreases expression EXP Phlorhizin results in decreased expression of DNAJA2 mRNA CTD PMID:22538082 NCBI chr 8:86,264,262...86,281,990
Ensembl chr 8:86,264,262...86,281,973
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression EXP Phlorhizin results in decreased expression of DNAJA3 mRNA CTD PMID:22538082 NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
increases expression
EXP Phlorhizin results in decreased expression of DNAJB1 mRNA
Phlorhizin results in increased expression of DNAJB1 mRNA
CTD PMID:22538082 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression EXP Phlorhizin results in decreased expression of DNAJB4 mRNA CTD PMID:22538082 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression EXP Phlorhizin results in increased expression of DNAJB6 mRNA CTD PMID:22538082 NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 decreases expression EXP Phlorhizin results in decreased expression of DNAJC1 mRNA CTD PMID:22538082 NCBI chr 2:18,210,445...18,402,025
Ensembl chr 2:18,200,465...18,397,641
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression EXP Phlorhizin results in decreased expression of DNAJC13 mRNA CTD PMID:22538082 NCBI chr 9:104,028,796...104,140,807
Ensembl chr 9:104,028,481...104,140,129
JBrowse link
G Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 increases expression EXP Phlorhizin results in increased expression of DNAJC14 mRNA CTD PMID:22538082 NCBI chr10:128,641,423...128,655,317
Ensembl chr10:128,639,931...128,655,315
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression EXP Phlorhizin results in decreased expression of DNAJC19 mRNA CTD PMID:22538082 NCBI chr 3:34,111,429...34,135,503
Ensembl chr 3:34,110,169...34,135,470
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression EXP Phlorhizin results in decreased expression of DNAJC3 mRNA CTD PMID:22538082 NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 increases expression EXP Phlorhizin results in increased expression of DNAJC4 mRNA CTD PMID:22538082 NCBI chr19:6,965,279...6,969,954
Ensembl chr19:6,965,279...6,969,940
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression EXP Phlorhizin results in decreased expression of DNAJC5 mRNA CTD PMID:22538082 NCBI chr 2:181,162,141...181,194,679
Ensembl chr 2:181,162,278...181,196,926
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial decreases expression EXP Phlorhizin results in decreased expression of ECHS1 mRNA CTD PMID:22538082 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
JBrowse link
G Ep300 E1A binding protein p300 decreases expression EXP Phlorhizin results in decreased expression of EP300 mRNA CTD PMID:22538082 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal decreases expression EXP Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Phlorhizin results in decreased expression of FAS mRNA CTD PMID:16123366 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 decreases expression EXP Phlorhizin results in decreased expression of FBXW7 mRNA CTD PMID:22538082 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505
JBrowse link
G Fh1 fumarate hydratase 1 decreases expression EXP Phlorhizin results in decreased expression of FH mRNA CTD PMID:22538082 NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Phlorhizin results in increased expression of FIS1 mRNA CTD PMID:22538082 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Fkbp5 FK506 binding protein 5 decreases expression EXP Phlorhizin results in decreased expression of FKBP5 mRNA CTD PMID:22538082 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Fmo1 flavin containing monooxygenase 1 decreases expression EXP Phlorhizin results in decreased expression of FMO1 mRNA CTD PMID:22538082 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA] CTD PMID:12446591 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP Phlorhizin results in decreased expression of GCLC mRNA CTD PMID:22538082 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit decreases expression EXP Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Glrx2 glutaredoxin 2 decreases expression EXP Phlorhizin results in decreased expression of GLRX2 mRNA CTD PMID:22538082 NCBI chr 1:143,614,787...143,625,416
Ensembl chr 1:143,592,076...143,625,414
JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial increases expression
decreases expression
EXP Phlorhizin results in increased expression of GPD2 mRNA
Phlorhizin results in decreased expression of GPD2 mRNA
CTD PMID:16123366 PMID:22538082 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP Phlorhizin results in decreased expression of GPX1 mRNA CTD PMID:16123366 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression EXP Phlorhizin results in increased expression of GPX7 mRNA CTD PMID:22538082 NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) decreases expression EXP Phlorhizin results in decreased expression of GSTA5 mRNA CTD PMID:22538082 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression EXP Phlorhizin results in decreased expression of GSTK1 mRNA CTD PMID:22538082 NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases expression EXP Phlorhizin results in decreased expression of GSTM1 mRNA CTD PMID:22538082 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 increases expression
decreases expression
EXP Phlorhizin results in increased expression of GSTM2 mRNA; Phlorhizin results in increased expression of GSTM5 mRNA
Phlorhizin results in decreased expression of GSTM5 mRNA
CTD PMID:22538082 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstm4 glutathione S-transferase, mu 4 increases expression EXP Phlorhizin results in increased expression of GSTM4 mRNA CTD PMID:22538082 NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression EXP Phlorhizin results in increased expression of GSTP1 mRNA CTD PMID:22538082 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 decreases expression
increases expression
EXP Phlorhizin results in decreased expression of GSTT1 mRNA
Phlorhizin results in increased expression of GSTT1 mRNA
CTD PMID:22538082 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression EXP Phlorhizin results in decreased expression of GSTT2B mRNA CTD PMID:22538082 NCBI chr10:75,667,676...75,673,253
Ensembl chr10:75,666,948...75,673,258
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression EXP Phlorhizin results in decreased expression of HACD3 mRNA CTD PMID:22538082 NCBI chr 9:64,894,265...64,929,014
Ensembl chr 9:64,894,265...64,928,975
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP Phlorhizin results in increased expression of HADHB mRNA CTD PMID:22538082 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 decreases expression EXP Phlorhizin results in decreased expression of HERPUD1 mRNA CTD PMID:22538082 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase decreases expression EXP Phlorhizin results in decreased expression of HIBADH mRNA CTD PMID:22538082 NCBI chr 6:52,523,215...52,617,285
Ensembl chr 6:52,523,213...52,617,374
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 decreases expression EXP Phlorhizin results in decreased expression of HMGCS1 mRNA CTD PMID:22538082 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP Phlorhizin results in decreased expression of HMOX1 mRNA CTD PMID:16123366 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases expression EXP Phlorhizin results in increased expression of HRAS mRNA CTD PMID:22538082 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression EXP Phlorhizin results in decreased expression of HSD17B10 mRNA CTD PMID:22538082 NCBI chr  X:150,784,892...150,787,438
Ensembl chr  X:150,784,841...150,787,438
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression EXP Phlorhizin results in decreased expression of HSD17B4 mRNA CTD PMID:22538082 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 decreases expression EXP Phlorhizin results in decreased expression of HSP90AA1 mRNA CTD PMID:22538082 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 decreases expression EXP Phlorhizin results in decreased expression of HSP90AB1 mRNA CTD PMID:22538082 NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
JBrowse link
G Hspa13 heat shock protein 70 family, member 13 decreases expression EXP Phlorhizin results in decreased expression of HSPA13 mRNA CTD PMID:22538082 NCBI chr16:75,552,078...75,564,575
Ensembl chr16:75,542,319...75,563,992
JBrowse link
G Hspa5 heat shock protein 5 increases expression EXP Phlorhizin results in increased expression of HSPA5 mRNA CTD PMID:22538082 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 increases expression EXP Phlorhizin results in increased expression of HSPA8 mRNA CTD PMID:22538082 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspa9 heat shock protein 9 decreases expression EXP Phlorhizin results in decreased expression of HSPA9 mRNA CTD PMID:22538082 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
JBrowse link
G Hspb1 heat shock protein 1 increases expression EXP Phlorhizin results in increased expression of HSPB1 mRNA CTD PMID:22538082 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hspb8 heat shock protein 8 decreases expression EXP Phlorhizin results in decreased expression of HSPB8 mRNA CTD PMID:22538082 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) decreases expression EXP Phlorhizin results in decreased expression of HSPD1 mRNA CTD PMID:22538082 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) decreases expression EXP Phlorhizin results in decreased expression of HSPE1 mRNA CTD PMID:22538082 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression EXP Phlorhizin results in decreased expression of HTRA2 mRNA CTD PMID:22538082 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression EXP Phlorhizin results in decreased expression of ID1 mRNA CTD PMID:16123366 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial increases expression EXP Phlorhizin results in increased expression of IDH2 mRNA CTD PMID:22538082 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Idh3a isocitrate dehydrogenase 3 (NAD+) alpha decreases expression EXP Phlorhizin results in decreased expression of IDH3A mRNA CTD PMID:22538082 NCBI chr 9:54,493,795...54,511,946
Ensembl chr 9:54,493,618...54,511,945
JBrowse link
G Idh3b isocitrate dehydrogenase 3 (NAD+) beta decreases expression EXP Phlorhizin results in decreased expression of IDH3B mRNA CTD PMID:22538082 NCBI chr 2:130,121,229...130,126,371
Ensembl chr 2:130,121,229...130,126,467
JBrowse link
G Idh3g isocitrate dehydrogenase 3 (NAD+), gamma decreases expression EXP Phlorhizin results in decreased expression of IDH3G mRNA CTD PMID:22538082 NCBI chr  X:72,822,569...72,830,471
Ensembl chr  X:72,822,569...72,830,503
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL1B mRNA CTD PMID:32408695 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA CTD PMID:32408695 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ivd isovaleryl coenzyme A dehydrogenase decreases expression EXP Phlorhizin results in decreased expression of IVD mRNA CTD PMID:22538082 NCBI chr 2:118,692,475...118,713,388
Ensembl chr 2:118,692,435...118,713,390
JBrowse link
G Junb jun B proto-oncogene decreases expression EXP Phlorhizin results in decreased expression of JUNB mRNA CTD PMID:22538082 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Jund jun D proto-oncogene increases expression EXP Phlorhizin results in increased expression of JUND mRNA CTD PMID:22538082 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 increases expression EXP Phlorhizin results in increased expression of KCNJ11 mRNA CTD PMID:16123366 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 increases expression EXP Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog decreases expression EXP Phlorhizin results in decreased expression of KRAS mRNA CTD PMID:22538082 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Lep leptin multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA]; [2,2-bis(4-glycidyloxyphenyl)propane co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of LEP mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA CTD PMID:32408695 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Maf MAF bZIP transcription factor decreases expression EXP Phlorhizin results in decreased expression of MAF mRNA CTD PMID:22538082 NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533
JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) decreases expression EXP Phlorhizin results in decreased expression of MAFG mRNA CTD PMID:22538082 NCBI chr11:120,515,943...120,525,771
Ensembl chr11:120,515,943...120,524,426
JBrowse link
G Maob monoamine oxidase B decreases expression EXP Phlorhizin results in decreased expression of MAOB mRNA CTD PMID:22538082 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 increases expression EXP Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases expression EXP Phlorhizin results in increased expression of MAP2K6 mRNA CTD PMID:22538082 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 increases expression EXP Phlorhizin results in increased expression of MAP2K7 mRNA CTD PMID:22538082 NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 decreases expression EXP Phlorhizin results in decreased expression of MAP3K7 mRNA CTD PMID:22538082 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases expression EXP Phlorhizin results in increased expression of MAPK3 mRNA CTD PMID:22538082 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression EXP Phlorhizin results in decreased expression of MAPK9 mRNA CTD PMID:22538082 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) decreases expression EXP Phlorhizin results in decreased expression of MCCC2 mRNA CTD PMID:22538082 NCBI chr13:100,085,040...100,152,147
Ensembl chr13:100,085,038...100,152,147
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression EXP Phlorhizin results in decreased expression of MDM2 mRNA CTD PMID:22538082 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Med20 mediator complex subunit 20 decreases expression EXP Phlorhizin results in decreased expression of MED20 mRNA CTD PMID:22538082 NCBI chr17:47,922,510...47,935,176
Ensembl chr17:47,922,507...47,935,343
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression EXP Phlorhizin results in increased expression of MGST1 mRNA CTD PMID:22538082 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753
JBrowse link
G Mmut methylmalonyl-Coenzyme A mutase decreases expression EXP Phlorhizin results in decreased expression of MMUT mRNA CTD PMID:22538082 NCBI chr17:41,245,576...41,272,880
Ensembl chr17:41,245,576...41,272,879
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory decreases phosphorylation ISO Phlorhizin results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578
JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 increases expression EXP Phlorhizin results in increased expression of NDUFA12 mRNA CTD PMID:22538082 NCBI chr10:94,034,897...94,057,302
Ensembl chr10:94,034,582...94,057,305
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 increases expression EXP Phlorhizin results in increased expression of NDUFA2 mRNA CTD PMID:22538082 NCBI chr18:36,875,385...36,877,640
Ensembl chr18:36,875,385...36,877,610
JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression EXP Phlorhizin results in decreased expression of NDUFA3 mRNA CTD PMID:22538082 NCBI chr 7:3,620,372...3,623,162
Ensembl chr 7:3,620,372...3,623,326
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression EXP Phlorhizin results in increased expression of NDUFA7 mRNA CTD PMID:22538082 NCBI chr17:34,043,546...34,057,290
Ensembl chr17:34,043,546...34,057,291
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression EXP Phlorhizin results in increased expression of NDUFAB1 mRNA CTD PMID:22538082 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression EXP Phlorhizin results in decreased expression of NDUFAF1 mRNA CTD PMID:22538082 NCBI chr 2:119,485,927...119,493,302
Ensembl chr 2:119,485,927...119,493,308
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression EXP Phlorhizin results in decreased expression of NDUFB6 mRNA CTD PMID:22538082 NCBI chr 4:40,270,591...40,279,421
Ensembl chr 4:40,270,591...40,279,421
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression EXP Phlorhizin results in decreased expression of NDUFS1 mRNA CTD PMID:22538082 NCBI chr 1:63,182,751...63,215,981
Ensembl chr 1:63,182,755...63,215,992
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 decreases expression EXP Phlorhizin results in decreased expression of NDUFS4 mRNA CTD PMID:22538082 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 decreases expression EXP Phlorhizin results in decreased expression of NDUFS5 mRNA CTD PMID:22538082 NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 increases expression EXP Phlorhizin results in increased expression of NDUFS8 mRNA CTD PMID:22538082 NCBI chr19:3,958,863...3,962,774
Ensembl chr19:3,958,863...3,962,774
JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 decreases expression EXP Phlorhizin results in decreased expression of NEDD4 mRNA CTD PMID:22538082 NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134
JBrowse link
G Neurod1 neurogenic differentiation 1 increases expression EXP Phlorhizin results in increased expression of NEUROD1 mRNA CTD PMID:16123366 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression EXP Phlorhizin results in decreased expression of NFE2L2 mRNA CTD PMID:22538082 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP [Phlorhizin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane co-treated with cobaltous chloride] affects the expression of NFKB1 mRNA CTD PMID:32408695 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nkx6-1 NK6 homeobox 1 increases expression EXP Phlorhizin results in increased expression of NKX6-1 mRNA CTD PMID:16123366 NCBI chr 5:101,807,050...101,812,577
Ensembl chr 5:101,806,005...101,812,862
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions
decreases expression
ISO Phlorhizin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]
Phlorhizin results in decreased expression of NOS3 mRNA
CTD PMID:20021702 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nras neuroblastoma ras oncogene decreases expression EXP Phlorhizin results in decreased expression of NRAS mRNA CTD PMID:22538082 NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230
JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) decreases expression EXP Phlorhizin results in decreased expression of OGDH mRNA CTD PMID:22538082 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 increases expression EXP Phlorhizin results in increased expression of PARK7 mRNA CTD PMID:22538082 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pcca propionyl-Coenzyme A carboxylase, alpha polypeptide decreases expression EXP Phlorhizin results in decreased expression of PCCA mRNA CTD PMID:22538082 NCBI chr14:122,721,822...123,127,372
Ensembl chr14:122,771,736...123,128,512
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic decreases expression EXP Phlorhizin results in decreased expression of PCK1 mRNA CTD PMID:22538082 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pcx pyruvate carboxylase increases expression
decreases expression
EXP Phlorhizin results in increased expression of PCX mRNA
Phlorhizin results in decreased expression of PC mRNA
CTD PMID:16123366 PMID:22538082 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase increases expression
decreases expression
EXP Phlorhizin results in increased expression of PECR mRNA
Phlorhizin results in decreased expression of PECR mRNA
CTD PMID:22538082 NCBI chr 1:72,298,331...72,323,480
Ensembl chr 1:72,298,326...72,323,473
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha decreases expression EXP Phlorhizin results in decreased expression of PIK3C2A mRNA CTD PMID:22538082 NCBI chr 7:115,936,500...116,042,693
Ensembl chr 7:115,936,500...116,042,684
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 decreases expression EXP Phlorhizin results in decreased expression of PIK3C3 mRNA CTD PMID:22538082 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179
JBrowse link
G Pink1 PTEN induced putative kinase 1 increases expression EXP Phlorhizin results in increased expression of PINK1 mRNA CTD PMID:22538082 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP Phlorhizin results in increased expression of PRDX1 mRNA CTD PMID:22538082 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression EXP Phlorhizin results in decreased expression of PRDX5 mRNA CTD PMID:22538082 NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474
JBrowse link
G Prkch protein kinase C, eta increases expression EXP Phlorhizin results in increased expression of PRKCH mRNA CTD PMID:22538082 NCBI chr12:73,631,570...73,824,959
Ensembl chr12:73,631,570...73,824,959
JBrowse link
G Prkci protein kinase C, iota decreases expression EXP Phlorhizin results in decreased expression of PRKCI mRNA CTD PMID:22538082 NCBI chr 3:31,049,893...31,106,889
Ensembl chr 3:31,049,896...31,107,108
JBrowse link
G Prkd3 protein kinase D3 decreases expression EXP Phlorhizin results in decreased expression of PRKD3 mRNA CTD PMID:22538082 NCBI chr17:79,256,834...79,328,245
Ensembl chr17:79,256,834...79,328,245
JBrowse link
G Psma4 proteasome subunit alpha 4 decreases expression EXP Phlorhizin results in decreased expression of PSMA4 mRNA CTD PMID:22538082 NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314
JBrowse link
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 increases expression EXP Phlorhizin results in increased expression of PSMB1 mRNA CTD PMID:22538082 NCBI chr17:15,695,983...15,718,538
Ensembl chr17:15,695,283...15,720,013
JBrowse link
G Psmb2 proteasome (prosome, macropain) subunit, beta type 2 decreases expression EXP Phlorhizin results in decreased expression of PSMB2 mRNA CTD PMID:22538082 NCBI chr 4:126,571,460...126,603,503
Ensembl chr 4:126,571,423...126,603,507
JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 decreases expression EXP Phlorhizin results in decreased expression of PSMC1 mRNA CTD PMID:22538082 NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664
JBrowse link
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 increases expression
decreases expression
EXP Phlorhizin results in increased expression of PSMC4 mRNA
Phlorhizin results in decreased expression of PSMC4 mRNA
CTD PMID:22538082 NCBI chr 7:27,741,127...27,749,517
Ensembl chr 7:27,741,132...27,749,526
JBrowse link
G Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 decreases expression EXP Phlorhizin results in decreased expression of PSMC6 mRNA CTD PMID:22538082 NCBI chr14:45,567,285...45,587,150
Ensembl chr14:45,567,245...45,587,162
JBrowse link
G Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 decreases expression EXP Phlorhizin results in decreased expression of PSMD10 mRNA CTD PMID:22538082 NCBI chr  X:139,849,174...139,857,460
Ensembl chr  X:139,849,178...139,857,477
JBrowse link
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 decreases expression EXP Phlorhizin results in decreased expression of PSMD12 mRNA CTD PMID:22538082 NCBI chr11:107,370,354...107,388,862
Ensembl chr11:107,370,310...107,395,188
JBrowse link
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 decreases expression EXP Phlorhizin results in decreased expression of PSMD14 mRNA CTD PMID:22538082 NCBI chr 2:61,542,038...61,630,720
Ensembl chr 2:61,542,038...61,630,720
JBrowse link
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 decreases expression EXP Phlorhizin results in decreased expression of PSMD4 mRNA CTD PMID:22538082 NCBI chr 3:94,939,999...94,949,880
Ensembl chr 3:94,940,005...94,949,925
JBrowse link
G Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 increases expression EXP Phlorhizin results in increased expression of PSMD6 mRNA CTD PMID:22538082 NCBI chr14:8,348,818...8,357,578
Ensembl chr14:8,348,779...8,357,589
JBrowse link
G Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 decreases expression EXP Phlorhizin results in decreased expression of PSMD7 mRNA CTD PMID:22538082 NCBI chr 8:108,307,012...108,315,114
Ensembl chr 8:108,307,013...108,315,096
JBrowse link
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 decreases expression EXP Phlorhizin results in decreased expression of PSMD9 mRNA CTD PMID:22538082 NCBI chr 5:123,366,253...123,388,189
Ensembl chr 5:123,307,476...123,388,194
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 decreases expression EXP Phlorhizin results in decreased expression of RAF1 mRNA CTD PMID:22538082 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
JBrowse link
G Rdh14 retinol dehydrogenase 14 (all-trans and 9-cis) increases expression EXP Phlorhizin results in increased expression of RDH14 mRNA CTD PMID:22538082 NCBI chr12:10,440,752...10,445,562
Ensembl chr12:10,440,772...10,445,562
JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) decreases expression EXP Phlorhizin results in decreased expression of S100A6 mRNA CTD PMID:16123366 NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488
JBrowse link
G Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) decreases expression EXP Phlorhizin results in decreased expression of SDHA mRNA CTD PMID:22538082 NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399
JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) increases expression EXP Phlorhizin results in increased expression of SDHB mRNA CTD PMID:22538082 NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
JBrowse link
G Sds serine dehydratase decreases expression EXP Phlorhizin results in decreased expression of SDS mRNA CTD PMID:22538082 NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 increases expression EXP Phlorhizin results in increased expression of SLC2A2 mRNA CTD PMID:16123366 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Slc35a2 solute carrier family 35 (UDP-galactose transporter), member A2 increases expression EXP Phlorhizin results in increased expression of SLC35A2 mRNA CTD PMID:22538082 NCBI chr  X:7,750,189...7,760,699
Ensembl chr  X:7,750,267...7,760,731
JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 multiple interactions
decreases activity
affects binding
ISO
EXP
Phlorhizin inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside]; Phlorhizin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose
SLC5A1 protein binds to Phlorhizin
CTD PMID:12663055 PMID:12927799 PMID:16300400 PMID:17288452 PMID:17983207 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214
JBrowse link
G Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 decreases activity ISO Phlorhizin results in decreased activity of SLC5A2 protein CTD PMID:21128592 NCBI chr 7:127,864,855...127,871,602
Ensembl chr 7:127,864,829...127,871,602
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression EXP Phlorhizin results in increased expression of SOD1 mRNA CTD PMID:22538082 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression EXP Phlorhizin results in decreased expression of SOD2 mRNA CTD PMID:22538082 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression EXP Phlorhizin results in decreased expression of STIP1 mRNA CTD PMID:22538082 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335
JBrowse link
G Sucla2 succinate-Coenzyme A ligase, ADP-forming, beta subunit decreases expression EXP Phlorhizin results in decreased expression of SUCLA2 mRNA CTD PMID:22538082 NCBI chr14:73,790,226...73,833,584
Ensembl chr14:73,762,759...73,833,582
JBrowse link
G Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit decreases expression EXP Phlorhizin results in decreased expression of SUCLG2 mRNA CTD PMID:22538082 NCBI chr 6:95,449,992...95,695,799
Ensembl chr 6:95,449,990...95,695,781
JBrowse link
G Sugt1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) decreases expression EXP Phlorhizin results in decreased expression of SUGT1 mRNA CTD PMID:22538082 NCBI chr14:79,825,100...79,868,237
Ensembl chr14:79,825,131...79,872,636
JBrowse link
G Txn1 thioredoxin 1 decreases expression
increases expression
EXP Phlorhizin results in decreased expression of TXN mRNA
Phlorhizin results in increased expression of TXN mRNA
CTD PMID:22538082 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txn2 thioredoxin 2 increases expression EXP Phlorhizin results in increased expression of TXN2 mRNA CTD PMID:22538082 NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
JBrowse link
G Ubb ubiquitin B increases expression EXP Phlorhizin results in increased expression of UBB mRNA CTD PMID:22538082 NCBI chr11:62,442,329...62,444,037
Ensembl chr11:62,441,997...62,444,039
JBrowse link
G Ubc ubiquitin C decreases expression EXP Phlorhizin results in decreased expression of UBC mRNA CTD PMID:22538082 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B decreases expression EXP Phlorhizin results in decreased expression of UBE2B mRNA CTD PMID:22538082 NCBI chr11:51,875,965...51,894,972
Ensembl chr11:51,876,324...51,891,589
JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression EXP Phlorhizin results in decreased expression of UBE2F mRNA CTD PMID:22538082 NCBI chr 1:91,177,412...91,214,243
Ensembl chr 1:91,178,026...91,218,059
JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H decreases expression EXP Phlorhizin results in decreased expression of UBE2H mRNA CTD PMID:22538082 NCBI chr 6:30,211,288...30,304,538
Ensembl chr 6:30,211,288...30,304,538
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I decreases expression EXP Phlorhizin results in decreased expression of UBE2I mRNA CTD PMID:22538082 NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 decreases expression EXP Phlorhizin results in decreased expression of UBE2L3 mRNA CTD PMID:22538082 NCBI chr16:16,969,879...17,019,363
Ensembl chr16:16,969,877...17,020,513
JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M increases expression EXP Phlorhizin results in increased expression of UBE2M mRNA CTD PMID:22538082 NCBI chr 7:12,769,047...12,772,202
Ensembl chr 7:12,769,047...12,772,202
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression EXP Phlorhizin results in decreased expression of UBE2N mRNA CTD PMID:22538082 NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519
JBrowse link
G Ube2q1 ubiquitin-conjugating enzyme E2Q family member 1 increases expression EXP Phlorhizin results in increased expression of UBE2Q1 mRNA CTD PMID:22538082 NCBI chr 3:89,680,905...89,691,304
Ensembl chr 3:89,680,923...89,691,307
JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 decreases expression EXP Phlorhizin results in decreased expression of UBE2R2 mRNA CTD PMID:22538082 NCBI chr 4:41,136,021...41,193,370
Ensembl chr 4:41,135,743...41,193,380
JBrowse link
G Ube2v2 ubiquitin-conjugating enzyme E2 variant 2 decreases expression EXP Phlorhizin results in decreased expression of UBE2V2 mRNA CTD PMID:22538082 NCBI chr16:15,368,850...15,412,382
Ensembl chr16:15,369,941...15,413,637
JBrowse link
G Ube4a ubiquitination factor E4A increases expression EXP Phlorhizin results in increased expression of UBE4A mRNA CTD PMID:22538082 NCBI chr 9:44,834,425...44,877,021
Ensembl chr 9:44,834,425...44,876,898
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression EXP Phlorhizin results in increased expression of UBR2 mRNA CTD PMID:22538082 NCBI chr17:47,239,217...47,321,812
Ensembl chr17:47,239,221...47,321,482
JBrowse link
G Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) decreases expression EXP Phlorhizin results in decreased expression of UCHL3 mRNA CTD PMID:22538082 NCBI chr14:101,891,387...101,933,561
Ensembl chr14:101,891,403...101,933,561
JBrowse link
G Uchl5 ubiquitin carboxyl-terminal esterase L5 decreases expression EXP Phlorhizin results in decreased expression of UCHL5 mRNA CTD PMID:22538082 NCBI chr 1:143,652,993...143,683,204
Ensembl chr 1:143,653,010...143,683,204
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 decreases activity ISO Phlorhizin results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 decreases activity ISO Phlorhizin results in decreased activity of UGT1A10 protein CTD PMID:35868516 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO Phlorhizin results in decreased activity of UGT1A3 protein CTD PMID:35868516 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 decreases activity ISO Phlorhizin results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO Phlorhizin results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 decreases activity ISO Phlorhizin results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 decreases expression EXP Phlorhizin results in decreased expression of UQCRC2 mRNA CTD PMID:22538082 NCBI chr 7:120,234,412...120,258,746
Ensembl chr 7:120,234,399...120,258,747
JBrowse link
G Usp1 ubiquitin specific peptidase 1 increases expression EXP Phlorhizin results in increased expression of USP1 mRNA CTD PMID:22538082 NCBI chr 4:98,812,047...98,823,780
Ensembl chr 4:98,812,047...98,823,780
JBrowse link
G Usp14 ubiquitin specific peptidase 14 decreases expression EXP Phlorhizin results in decreased expression of USP14 mRNA CTD PMID:22538082 NCBI chr18:9,993,615...10,030,149
Ensembl chr18:9,993,066...10,045,119
JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression EXP Phlorhizin results in increased expression of USP19 mRNA CTD PMID:22538082 NCBI chr 9:108,367,806...108,379,536
Ensembl chr 9:108,367,801...108,379,536
JBrowse link
G Usp24 ubiquitin specific peptidase 24 decreases expression EXP Phlorhizin results in decreased expression of USP24 mRNA CTD PMID:22538082 NCBI chr 4:106,173,179...106,303,798
Ensembl chr 4:106,173,417...106,298,519
JBrowse link
G Usp33 ubiquitin specific peptidase 33 decreases expression EXP Phlorhizin results in decreased expression of USP33 mRNA CTD PMID:22538082 NCBI chr 3:152,051,797...152,099,254
Ensembl chr 3:152,052,115...152,099,254
JBrowse link
G Usp4 ubiquitin specific peptidase 4 (proto-oncogene) increases expression EXP Phlorhizin results in increased expression of USP4 mRNA CTD PMID:22538082 NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744
JBrowse link
G Usp45 ubiquitin specific petidase 45 decreases expression EXP Phlorhizin results in decreased expression of USP45 mRNA CTD PMID:22538082 NCBI chr 4:21,767,161...21,837,872
Ensembl chr 4:21,767,156...21,837,872
JBrowse link
G Usp46 ubiquitin specific peptidase 46 decreases expression EXP Phlorhizin results in decreased expression of USP46 mRNA CTD PMID:22538082 NCBI chr 5:74,159,387...74,229,070
Ensembl chr 5:74,159,114...74,229,092
JBrowse link
G Usp7 ubiquitin specific peptidase 7 decreases expression EXP Phlorhizin results in decreased expression of USP7 mRNA CTD PMID:22538082 NCBI chr16:8,506,586...8,574,931
Ensembl chr16:8,507,459...8,610,172
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X chromosome decreases expression EXP Phlorhizin results in decreased expression of USP9X mRNA CTD PMID:22538082 NCBI chr  X:12,937,221...13,039,567
Ensembl chr  X:12,937,737...13,039,567
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] results in increased expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of VEGFA mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] results in increased expression of VEGFA mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of VEGFA mRNA CTD PMID:32408695 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression EXP Phlorhizin results in decreased expression of XIAP mRNA CTD PMID:22538082 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
phlorizin chalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO isosalipurposide results in increased expression of HMOX1 protein CTD PMID:26028482 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO MAPK1 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein] CTD PMID:26028482 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO MAPK3 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein] CTD PMID:26028482 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
multiple interactions
ISO isosalipurposide affects the localization of NFE2L2 protein
MAPK1 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein]; MAPK3 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein]
CTD PMID:26028482 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
picrocrocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity
ISO 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [picrocrocin results in increased activity of TRPA1 protein] CTD PMID:30636360 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
JBrowse link
quercetin 3-O-beta-D-glucofuranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-Coenzyme A acetyltransferase 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Apoa1 apolipoprotein A-I increases secretion ISO isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atxn2 ataxin 2 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr 5:121,849,794...121,954,372
Ensembl chr 5:121,849,400...121,954,556
JBrowse link
G Atxn3 ataxin 3 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr12:101,885,160...101,928,139
Ensembl chr12:101,885,160...101,924,505
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 affects expression ISO isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 decreases expression ISO isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO isoquercitrin results in increased expression of CXCL8 mRNA CTD PMID:30597948 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
isoquercitrin results in decreased activity of CYP1A1 protein
CTD PMID:16271822 PMID:20033131 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
JBrowse link
G Cyp51 cytochrome P450, family 51 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Egf epidermal growth factor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
JBrowse link
G Fdps farnesyl diphosphate synthetase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions ISO [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Ibsp integrin binding sialoprotein increases expression ISO isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr 5:104,447,153...104,459,338
Ensembl chr 5:104,447,037...104,459,335
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein] CTD PMID:30817903 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
JBrowse link
G Jak2 Janus kinase 2 increases expression ISO isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Lct lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr 1:128,212,493...128,256,055
Ensembl chr 1:128,212,493...128,256,055
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 affects expression ISO isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
JBrowse link
G Nsf N-ethylmaleimide sensitive fusion protein multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr11:103,712,608...103,844,882
Ensembl chr11:103,712,608...103,844,882
JBrowse link
G Nsg1 neuron specific gene family member 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 5:38,294,537...38,317,087
Ensembl chr 5:38,294,536...38,317,251
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression ISO isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Ppid peptidylprolyl isomerase D (cyclophilin D) multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 3:79,498,644...79,511,117
Ensembl chr 3:79,498,649...79,510,957
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B increases expression ISO isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
JBrowse link
G Runx2 runt related transcription factor 2 increases expression ISO isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sc5d sterol-C5-desaturase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 multiple interactions ISO isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214
JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression ISO isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Tyk2 tyrosine kinase 2 affects expression ISO isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
JBrowse link
quercetin 3-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-Coenzyme A acetyltransferase 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Apoa1 apolipoprotein A-I increases secretion ISO isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atxn2 ataxin 2 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr 5:121,849,794...121,954,372
Ensembl chr 5:121,849,400...121,954,556
JBrowse link
G Atxn3 ataxin 3 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr12:101,885,160...101,928,139
Ensembl chr12:101,885,160...101,924,505
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 affects expression ISO isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 decreases expression ISO isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO isoquercitrin results in increased expression of CXCL8 mRNA CTD PMID:30597948 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO isoquercitrin results in decreased activity of CYP1A1 protein
[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
CTD PMID:16271822 PMID:20033131 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
JBrowse link
G Cyp51 cytochrome P450, family 51 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Egf epidermal growth factor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
JBrowse link
G Fdps farnesyl diphosphate synthetase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions ISO [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Ibsp integrin binding sialoprotein increases expression ISO isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr 5:104,447,153...104,459,338
Ensembl chr 5:104,447,037...104,459,335
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein] CTD PMID:30817903 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
JBrowse link
G Jak2 Janus kinase 2 increases expression ISO isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Lct lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr 1:128,212,493...128,256,055
Ensembl chr 1:128,212,493...128,256,055
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 affects expression ISO isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
JBrowse link
G Nsf N-ethylmaleimide sensitive fusion protein multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr11:103,712,608...103,844,882
Ensembl chr11:103,712,608...103,844,882
JBrowse link
G Nsg1 neuron specific gene family member 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 5:38,294,537...38,317,087
Ensembl chr 5:38,294,536...38,317,251
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression ISO isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Ppid peptidylprolyl isomerase D (cyclophilin D) multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 3:79,498,644...79,511,117
Ensembl chr 3:79,498,649...79,510,957
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B increases expression ISO isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
JBrowse link
G Runx2 runt related transcription factor 2 increases expression ISO isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sc5d sterol-C5-desaturase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 multiple interactions ISO isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214
JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression ISO isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Tyk2 tyrosine kinase 2 affects expression ISO isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
JBrowse link
quercetin 4'-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:32602595 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Ap5m1 adaptor-related protein complex 5, mu 1 subunit decreases expression ISO spiraeoside results in decreased expression of AP5M1 protein CTD PMID:34116102 NCBI chr14:49,303,869...49,331,681
Ensembl chr14:49,303,554...49,331,691
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein] CTD PMID:32602595 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
spiraeoside results in decreased expression of BCL2 protein
CTD PMID:32602595 PMID:34116102 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO spiraeoside results in decreased expression of BID protein CTD PMID:34116102 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Casp3 caspase 3 decreases expression ISO spiraeoside results in decreased expression of CASP3 protein CTD PMID:34116102 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 decreases expression ISO spiraeoside results in decreased expression of CASP9 protein CTD PMID:34116102 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] CTD PMID:32602595 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO spiraeoside results in decreased expression of CDK2 protein CTD PMID:34116102 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cryz crystallin, zeta increases activity EXP spiraeoside results in increased activity of CRYZ protein CTD PMID:8968052 NCBI chr 3:154,302,348...154,328,819
Ensembl chr 3:154,302,348...154,328,819
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein] CTD PMID:32602595 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Lct lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside CTD PMID:12663055 NCBI chr 1:128,212,493...128,256,055
Ensembl chr 1:128,212,493...128,256,055
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein] CTD PMID:32602595 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Plcg2 phospholipase C, gamma 2 decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of PLCG2 protein CTD PMID:15613018 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881
JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 multiple interactions ISO [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
CTD PMID:12663055 PMID:17495124 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214
JBrowse link
G Syk spleen tyrosine kinase decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of SYK protein CTD PMID:15613018 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
rebaudioside A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression ISO rebaudioside A results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:30883860 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO rebaudioside A results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO rebaudioside A results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Bax BCL2-associated X protein decreases expression ISO rebaudioside A results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases expression ISO rebaudioside A results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Cat catalase multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cav1 caveolin 1, caveolae protein decreases expression ISO rebaudioside A results in decreased expression of CAV1 mRNA CTD PMID:31655124 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO rebaudioside A results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO rebaudioside A results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
JBrowse link
G Edn1 endothelin 1 decreases expression ISO rebaudioside A results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednra endothelin receptor type A increases expression ISO rebaudioside A results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G F2r coagulation factor II thrombin receptor decreases expression ISO rebaudioside A results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G Fasl Fas ligand increases expression ISO rebaudioside A results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO rebaudioside A results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 decreases expression ISO rebaudioside A results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Il10 interleukin 10 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL10 protein] CTD PMID:30883860 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il6 interleukin 6 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL6 protein] CTD PMID:30883860 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Insr insulin receptor multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Itgav integrin alpha V decreases expression ISO rebaudioside A results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO rebaudioside A results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lipc lipase, hepatic multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein] CTD PMID:30883860 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP2 protein] CTD PMID:30883860 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
ISO rebaudioside A results in increased expression of MMP9 mRNA
rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP9 protein]
CTD PMID:30883860 PMID:31655124 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 protein] CTD PMID:30883860 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pf4 platelet factor 4 increases expression ISO rebaudioside A results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO rebaudioside A results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of RELA protein] CTD PMID:30883860 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Sele selectin, endothelial cell decreases expression ISO rebaudioside A results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Smad7 SMAD family member 7 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] CTD PMID:30883860 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions EXP rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] CTD PMID:30883860 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TNF protein] CTD PMID:30883860 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 decreases expression ISO rebaudioside A results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
salicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of salicin CTD PMID:8831264 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Tas2r118 taste receptor, type 2, member 118 multiple interactions
increases activity
ISO 4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein] CTD PMID:21629661 NCBI chr 6:23,969,160...23,970,059
Ensembl chr 6:23,969,160...23,970,059
JBrowse link
scopolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ide insulin degrading enzyme multiple interactions ISO scopolin binds to and affects the activity of IDE protein CTD PMID:23146021 NCBI chr19:37,246,140...37,341,664
Ensembl chr19:37,246,142...37,340,010
JBrowse link
G Urod uroporphyrinogen decarboxylase multiple interactions ISO scopolin binds to and affects the activity of UROD protein CTD PMID:23209648 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610
JBrowse link
stevioside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression ISO stevioside results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein] CTD PMID:20871768 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases secretion ISO stevioside results in decreased secretion of ACP5 protein CTD PMID:21089163 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO stevioside results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO stevioside results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Bax BCL2-associated X protein decreases expression ISO stevioside results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases expression ISO stevioside results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Cat catalase multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO stevioside results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO stevioside results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO stevioside results in increased expression of CYP1A1 mRNA CTD PMID:28887089 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO stevioside results in increased expression of CYP1A2 mRNA; stevioside results in increased expression of CYP1A2 protein CTD PMID:28887089 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO stevioside results in increased expression of CYP1B1 mRNA CTD PMID:28887089 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases expression ISO stevioside results in decreased expression of CYP2C9 mRNA CTD PMID:28887089 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
JBrowse link
G Edn1 endothelin 1 decreases expression ISO stevioside results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednra endothelin receptor type A increases expression ISO stevioside results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G F2r coagulation factor II thrombin receptor decreases expression ISO stevioside results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G Fasl Fas ligand increases expression ISO stevioside results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO stevioside results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 decreases expression ISO stevioside results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Insr insulin receptor multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Itgav integrin alpha V decreases expression ISO stevioside results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO stevioside results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lipc lipase, hepatic multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO stevioside results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pf4 platelet factor 4 increases expression ISO stevioside results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
JBrowse link
G Plin2 perilipin 2 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] CTD PMID:25554529 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO stevioside results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Sele selectin, endothelial cell decreases expression ISO stevioside results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions EXP stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 decreases expression ISO stevioside results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
syringin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein increases expression ISO syringin results in increased expression of BAX protein CTD PMID:35580997 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO syringin results in decreased expression of BCL2 protein CTD PMID:35580997 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO syringin results in decreased expression of BIRC5 protein CTD PMID:35580997 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein] CTD PMID:33146439 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO syringin results in increased expression of CCND1 protein CTD PMID:35580997 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cdh1 cadherin 1 increases expression ISO syringin results in increased expression of CDH1 protein CTD PMID:35580997 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Ifng interferon gamma multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein] CTD PMID:33146439 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il13 interleukin 13 multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:33146439 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il4 interleukin 4 multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:33146439 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:33146439 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein] CTD PMID:33146439 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein] CTD PMID:33146439 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein] CTD PMID:33146439 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases phosphorylation ISO syringin results in increased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein] CTD PMID:33146439 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO syringin results in decreased expression of SQSTM1 protein CTD PMID:35580997 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein] CTD PMID:33146439 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO syringin results in increased expression of TP53 protein CTD PMID:35580997 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
tannic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO Tannic Acid inhibits the reaction [aluminum acetate results in decreased activity of ACHE protein]; Tannic Acid inhibits the reaction [lead acetate results in decreased activity of ACHE protein] CTD PMID:25496357 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 mRNA] CTD PMID:35987278 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP9 mRNA] CTD PMID:35987278 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in decreased activity of CAT protein] CTD PMID:35987278 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of FOXO1 mRNA] CTD PMID:35987278 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 mRNA] CTD PMID:35987278 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in decreased expression of GPX1 mRNA] CTD PMID:35987278 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) multiple interactions ISO Tannic Acid inhibits the reaction [aluminum acetate results in decreased expression of GRIN2A protein] CTD PMID:25496357 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions ISO Tannic Acid inhibits the reaction [aluminum acetate results in decreased expression of GRIN2B protein] CTD PMID:25496357 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in decreased expression of GSTA5 mRNA] CTD PMID:35987278 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA] CTD PMID:35987278 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA] CTD PMID:35987278 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of LCN2 mRNA] CTD PMID:35987278 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of PTGS2 mRNA] CTD PMID:35987278 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in decreased activity of SOD1 protein]; Tannic Acid inhibits the reaction [Doxorubicin results in decreased expression of SOD1 mRNA] CTD PMID:35987278 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA] CTD PMID:35987278 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Top2b topoisomerase (DNA) II beta multiple interactions ISO Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of TOP2B mRNA] CTD PMID:35987278 NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584
JBrowse link
tectoridin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-Coenzyme A dehydrogenase, medium chain multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:20637825 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:20637825 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:20637825 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of CYP4A10 mRNA] CTD PMID:20637825 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of CYP4A14 mRNA] CTD PMID:20637825 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:20637825 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:20637825 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions EXP [Xiao-Ke-An results in increased abundance of tectoridin] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:20637825 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA] CTD PMID:20637825 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
teniposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C member 1 decreases response to substance EXP ABCC1 results in decreased susceptibility to Teniposide CTD PMID:8968083 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Ar androgen receptor multiple interactions ISO Teniposide binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO Teniposide results in increased expression of CDKN1A mRNA; Teniposide results in increased expression of CDKN1A protein CTD PMID:25914138 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases methylation ISO CYP3A5 protein results in decreased methylation of Teniposide CTD PMID:8114683 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Teniposide binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO Teniposide binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases response to substance ISO FGF2 protein results in decreased susceptibility to Teniposide CTD PMID:20221717 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO Teniposide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Mir135b microRNA 135b decreases response to substance ISO MIR135B mRNA results in decreased susceptibility to Teniposide CTD PMID:27570640 NCBI chr 1:132,125,826...132,125,922
Ensembl chr 1:132,125,826...132,125,922
JBrowse link
G Mir196b microRNA 196b decreases response to substance ISO MIR196B mRNA results in decreased susceptibility to Teniposide CTD PMID:27570640 NCBI chr 6:52,207,061...52,207,145
Ensembl chr 6:52,207,061...52,207,145
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression
multiple interactions
EXP Teniposide results in decreased expression of MTTP mRNA
Teniposide promotes the reaction [CETP protein results in decreased expression of MTTP mRNA]
CTD PMID:25914138 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO Teniposide results in decreased expression of MYC mRNA; Teniposide results in decreased expression of MYC protein CTD PMID:11585056 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions
affects localization
affects response to substance
ISO NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]
Teniposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Teniposide
CTD PMID:25914138 NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression
affects response to substance
ISO NR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Teniposide results in increased expression of and affects the localization of NR1H3 protein
Teniposide results in increased expression of NR1H3 mRNA
NR1H3 protein affects the susceptibility to Teniposide
CTD PMID:25914138 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 decreases expression ISO Teniposide results in decreased expression of NRIP1 mRNA; Teniposide results in decreased expression of NRIP1 protein CTD PMID:25914138 NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 decreases expression ISO Teniposide results in decreased expression of ODC1 protein CTD PMID:11585056 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Teniposide binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]] CTD PMID:25914138 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Teniposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Teniposide binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Teniposide binds to and results in decreased activity of THRB protein CTD PMID:25752796 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Top2a topoisomerase (DNA) II alpha multiple interactions ISO TOP2A results in decreased susceptibility to [Cisplatin co-treated with Teniposide] CTD PMID:11325482 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
trans-piceid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 affects export ISO ABCC2 protein affects the export of polydatin CTD PMID:15686436 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Agt angiotensinogen multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB protein]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of MYH7 mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 protein]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein] CTD PMID:25488910 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Ahr aryl-hydrocarbon receptor decreases localization
multiple interactions
ISO polydatin results in decreased localization of AHR protein
polydatin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]
CTD PMID:21756928 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases localization ISO polydatin results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO polydatin inhibits the reaction [Rotenone results in decreased expression of ATG5 protein] CTD PMID:31926197 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions EXP
ISO
cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]
polydatin inhibits the reaction [Dopamine results in decreased expression of BCL2 protein]
CTD PMID:27481074 PMID:28980048 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cat catalase multiple interactions EXP
ISO
cyclopamine inhibits the reaction [polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]
polydatin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]
CTD PMID:27481074 PMID:29130132 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
decreases expression
ISO polydatin inhibits the reaction [leptomycin B results in increased secretion of CCL2 protein]; polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]; polydatin inhibits the reaction [PD168393 results in increased expression of CCL2 mRNA]
polydatin results in decreased secretion of CCL2 protein
polydatin results in decreased expression of CCL2 mRNA
CTD PMID:21756928 PMID:21967610 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA] CTD PMID:27481074 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd2 cyclin D2 multiple interactions EXP cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA] CTD PMID:27481074 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
decreases secretion
decreases expression
ISO [polydatin co-treated with TGFA protein] results in increased expression of CXCL10 mRNA; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin inhibits the reaction [PD168393 results in increased expression of CXCL10 mRNA]
polydatin results in decreased secretion of CXCL10 protein
polydatin results in decreased expression of CXCL10 mRNA
CTD PMID:21756928 PMID:21967610 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases secretion
decreases expression
ISO [polydatin co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 mRNA]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
polydatin results in increased secretion of CXCL8 protein
polydatin results in decreased expression of CXCL8 mRNA
CTD PMID:21756928 PMID:21967610 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cybb cytochrome b-245, beta polypeptide multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB protein] CTD PMID:25488910 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO polydatin results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions EXP ESR2 gene mutant form inhibits the reaction [polydatin results in increased expression of SOD2 protein] CTD PMID:24361291 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO polydatin results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gli1 GLI-Kruppel family member GLI1 multiple interactions EXP cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein] CTD PMID:27481074 NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843
JBrowse link
G Hlcs holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) decreases activity ISO polydatin results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr16:93,930,054...94,116,098
Ensembl chr16:93,929,741...94,114,430
JBrowse link
G Ifng interferon gamma multiple interactions ISO polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B mRNA] CTD PMID:29130132 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 multiple interactions ISO polydatin inhibits the reaction [OVAL protein results in increased secretion of IL4 protein] CTD PMID:23840142 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
polydatin results in decreased expression of IL6 mRNA
CTD PMID:21756928 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO
EXP
polydatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein]
polydatin inhibits the reaction [TSHR protein results in increased expression of KEAP1 protein]
CTD PMID:31705858 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Lct lactase increases hydrolysis ISO LCT protein results in increased hydrolysis of polydatin analog CTD PMID:17009167 NCBI chr 1:128,212,493...128,256,055
Ensembl chr 1:128,212,493...128,256,055
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
ISO polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [polydatin results in increased phosphorylation of MAPK1 protein]
polydatin results in decreased phosphorylation of MAPK1 protein
CTD PMID:21756928 PMID:28980048 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation
ISO polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [polydatin results in increased phosphorylation of MAPK3 protein]
polydatin results in decreased phosphorylation of MAPK3 protein
CTD PMID:21756928 PMID:28980048 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions
increases phosphorylation
ISO XMD 8-92 inhibits the reaction [polydatin results in increased phosphorylation of MAPK7 protein] CTD PMID:28980048 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO polydatin inhibits the reaction [Rotenone results in increased expression of MFN2 protein] CTD PMID:31926197 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO polydatin inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein] CTD PMID:31926197 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of MYH7 mRNA] CTD PMID:25488910 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO
EXP
[polydatin co-treated with Hydrogen Peroxide] results in increased expression of NFE2L2 protein; NFE2L2 protein affects the reaction [[polydatin co-treated with Hydrogen Peroxide] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [polydatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]]
polydatin inhibits the reaction [TSHR protein results in decreased expression of NFE2L2 protein]
CTD PMID:31705858 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 protein] CTD PMID:25488910 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
JBrowse link
G Nppa natriuretic peptide type A multiple interactions ISO polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased expression of NPPA protein]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; polydatin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein] CTD PMID:25449040 PMID:25488910 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO
EXP
NFE2L2 protein affects the reaction [polydatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]]; polydatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]
polydatin inhibits the reaction [TSHR protein results in decreased expression of NQO1 protein]
CTD PMID:31705858 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 affects response to substance EXP ORAI1 protein affects the susceptibility to polydatin CTD PMID:22959927 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 multiple interactions ISO [PRKN protein affects the susceptibility to polydatin] which results in increased expression of PARK7 protein; polydatin inhibits the reaction [Rotenone results in increased expression of PARK7 protein] CTD PMID:31926197 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific decreases activity ISO polydatin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta decreases expression ISO polydatin results in decreased expression of PPARGC1B protein CTD PMID:31926197 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A protein]; polydatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein] CTD PMID:25449040 NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase affects response to substance
multiple interactions
ISO PRKN protein affects the susceptibility to polydatin
[PRKN protein affects the susceptibility to polydatin] which results in increased expression of PARK7 protein
CTD PMID:31926197 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity EXP polydatin results in decreased activity of PTGS1 protein CTD PMID:11962253 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
ISO
EXP
[polydatin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA
polydatin results in decreased activity of PTGS2 protein
CTD PMID:11962253 PMID:21756928 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA mRNA]
CTD PMID:21756928 PMID:29130132 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO polydatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein] CTD PMID:25449040 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Shh sonic hedgehog multiple interactions EXP polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of and results in increased secretion of SHH protein] CTD PMID:27481074 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO polydatin inhibits the reaction [Rotenone results in decreased expression of SIRT1 protein] CTD PMID:31926197 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein] CTD PMID:22865646 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein] CTD PMID:22865646 NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062
JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:22865646 NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916
JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein] CTD PMID:22865646 NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] CTD PMID:22865646 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
JBrowse link
G Slc2a9 solute carrier family 2 (facilitated glucose transporter), member 9 multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein] CTD PMID:22865646 NCBI chr 5:38,506,616...38,660,488
Ensembl chr 5:38,506,616...38,660,486
JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 affects uptake ISO SLC5A1 protein affects the uptake of polydatin CTD PMID:15686436 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions
increases expression
ISO
EXP
polydatin results in increased expression of and results in increased activity of SOD2 protein
polydatin results in increased expression of SOD2 protein
ESR2 gene mutant form inhibits the reaction [polydatin results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [polydatin results in increased expression of SOD2 protein]
CTD PMID:24361291 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO polydatin promotes the reaction [Rotenone results in decreased expression of SQSTM1 protein] CTD PMID:31926197 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO [polydatin co-treated with TGFA protein] results in increased expression of CXCL10 mRNA; [polydatin co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21756928 PMID:21967610 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein] CTD PMID:25488910 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]
polydatin results in decreased expression of TNF mRNA
CTD PMID:21756928 PMID:29130132 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA] CTD PMID:29130132 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tshr thyroid stimulating hormone receptor multiple interactions EXP polydatin inhibits the reaction [TSHR protein results in decreased expression of NFE2L2 protein]; polydatin inhibits the reaction [TSHR protein results in decreased expression of NQO1 protein]; polydatin inhibits the reaction [TSHR protein results in increased expression of KEAP1 protein] CTD PMID:31705858 NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
JBrowse link
G Tug1 taurine upregulated gene 1 decreases expression ISO polydatin results in decreased expression of TUG1 mRNA CTD PMID:30974157 NCBI chr11:3,589,313...3,599,021
Ensembl chr11:3,589,785...3,599,673
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases hydrolysis ISO UGT1A1 protein results in increased hydrolysis of polydatin metabolite CTD PMID:17009167 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ulk1 unc-51 like kinase 1 multiple interactions ISO polydatin inhibits the reaction [Rotenone results in increased phosphorylation of ULK1 protein] CTD PMID:31926197 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963
JBrowse link
G Umod uromodulin multiple interactions EXP polydatin inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein] CTD PMID:22865646 NCBI chr 7:119,061,931...119,078,485
Ensembl chr 7:119,061,934...119,078,505
JBrowse link
trans-rhaponticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32662907 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] CTD PMID:32662907 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il10 interleukin 10 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] CTD PMID:32662907 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Ins1 insulin I multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:32662907 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] CTD PMID:32662907 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] CTD PMID:32662907 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] CTD PMID:32662907 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] CTD PMID:32662907 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:32662907 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
trilobatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein] CTD PMID:30104959 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:30104959 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cat catalase multiple interactions EXP NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein] CTD PMID:32663520 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein] CTD PMID:30104959 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein] CTD PMID:30104959 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein] CTD PMID:30104959 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP
ISO
trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 protein]
trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]
CTD PMID:30104959 PMID:32663520 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein] CTD PMID:30104959 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:25053100 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:25053100 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP6 mRNA] CTD PMID:30104959 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COX1 mRNA] CTD PMID:30104959 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G mt-Cytb cytochrome b, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CYTB mRNA] CTD PMID:30104959 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288
JBrowse link
G mt-Nd2 NADH dehydrogenase 2, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND2 mRNA] CTD PMID:30104959 NCBI chr MT:3,914...4,951
Ensembl chr MT:3,914...4,951
JBrowse link
G mt-Nd5 NADH dehydrogenase 5, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND5 mRNA] CTD PMID:30104959 NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO
EXP
trilobatin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]
NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin promotes the reaction [Isoflurane results in increased expression of NFE2L2 protein]
CTD PMID:30104959 PMID:32663520 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:25053100 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP
ISO
trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 protein]
trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]
CTD PMID:30104959 PMID:32663520 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] CTD PMID:30104959 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:25053100 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein] CTD PMID:30104959 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in increased acetylation of SOD2 protein] CTD PMID:30104959 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:25053100 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein] CTD PMID:30104959 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22188
    chemical entity 22187
      atom 22180
        nonmetal atom 22063
          oxygen atom 21414
            oxygen molecular entity 21414
              organooxygen compound 20809
                carbohydrates and carbohydrate derivatives 16038
                  carbohydrate derivative 14786
                    glycosyl compound 13160
                      glycoside 11876
                        hexoside 1595
                          glucoside 1581
                            2-trans-abscisic acid D-glucosyl ester + 0
                            D-glucoside + 1581
                            L-glucoside + 0
                            alpha-glucoside + 168
                            beta-D-glucosyl-(1->2)-D-glucoside 0
                            beta-glucoside + 1478
                            loganic acid 0
                            methyl glucoside + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    p-block element atom 22114
                      carbon group element atom 21915
                        carbon atom 21840
                          organic molecular entity 21840
                            heteroorganic entity 21489
                              organochalcogen compound 20972
                                organooxygen compound 20809
                                  carbohydrates and carbohydrate derivatives 16038
                                    carbohydrate 16038
                                      carbohydrate derivative 14786
                                        glycosyl compound 13160
                                          glycoside 11876
                                            hexoside 1595
                                              glucoside 1581
                                                2-trans-abscisic acid D-glucosyl ester + 0
                                                D-glucoside + 1581
                                                L-glucoside + 0
                                                alpha-glucoside + 168
                                                beta-D-glucosyl-(1->2)-D-glucoside 0
                                                beta-glucoside + 1478
                                                loganic acid 0
                                                methyl glucoside + 0
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