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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glucoside
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Accession:CHEBI:24278 term browser browse the term
Synonyms:related_synonym: glucosides


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(+)-syringaresinol beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] CTD PMID:31077737 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein CTD PMID:31077737 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cat catalase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:31077737 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] CTD PMID:31077737 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Il10 interleukin 10 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:31077737 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] CTD PMID:31077737 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] CTD PMID:31077737 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:31077737 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein CTD PMID:31077737 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] CTD PMID:31077737 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] CTD PMID:31077737 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
(20S)-ginsenoside Rh1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO ginsenoside Rh1 results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21875580 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] CTD PMID:16557482 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases expression ISO ginsenoside Rh1 results in decreased expression of IL4 CTD PMID:22855946 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itga4 integrin subunit alpha 4 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases activity ISO ginsenoside Rh1 results in decreased activity of JUN protein CTD PMID:22855946 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lpl lipoprotein lipase increases secretion ISO ginsenoside Rh1 results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Pgr progesterone receptor increases expression ISO ginsenoside Rh1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] CTD PMID:16557482 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Sele selectin E multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:21875580 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO ginsenoside Rh1 results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases response to substance
ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]
ginsenoside Rh1 results in decreased expression of TNF
ginsenoside Rh1 results in decreased susceptibility to TNF protein
CTD PMID:16557482, PMID:21875580, PMID:22855946 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:21875580 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
(20S)-ginsenoside Rh2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO ginsenoside Rh2 results in increased expression of BAX protein CTD PMID:26482938 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO ginsenoside Rh2 results in decreased expression of BCL2 protein CTD PMID:26482938 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases cleavage ISO ginsenoside Rh2 results in increased cleavage of CASP3 protein CTD PMID:26482938 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO ginsenoside Rh2 results in decreased expression of CCND1 protein CTD PMID:26482938 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC1 protein CTD PMID:26482938 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC2 protein CTD PMID:26482938 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac6 histone deacetylase 6 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC6 protein CTD PMID:26482938 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rh2 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO ginsenoside Rh2 results in decreased phosphorylation of MAPK1 protein CTD PMID:26482938 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO ginsenoside Rh2 results in decreased phosphorylation of MAPK3 protein CTD PMID:26482938 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ACACA mRNA] CTD PMID:30721698 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 protein]
CTD PMID:16253226, PMID:30721698 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA protein] CTD PMID:30721698 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FAS mRNA] CTD PMID:30721698 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:16253226 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of IL6 protein] CTD PMID:30721698 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ACACA mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FAS mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK9 protein] CTD PMID:30721698 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:30721698 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:30721698 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK9 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein] CTD PMID:30721698 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG protein] CTD PMID:30721698 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased localization of RELA protein] CTD PMID:16253226 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 protein] CTD PMID:30721698 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 protein] CTD PMID:30721698 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased localization of RELA protein]
beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of IL6 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein]
CTD PMID:16253226, PMID:30721698 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:16253226 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
4-methylumbelliferyl beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gaa glucosidase, alpha, acid multiple interactions
increases metabolic processing
ISO GAA gene SNP inhibits the reaction [GAA protein results in increased metabolism of 4-methylumbelliferyl glucoside] CTD PMID:21963784 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
albiflorin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects expression EXP albiflorin affects the expression of DRD2 CTD PMID:26475043 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A affects expression EXP albiflorin affects the expression of HTR1A CTD PMID:26475043 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects expression EXP albiflorin affects the expression of HTR2A CTD PMID:26475043 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects expression EXP albiflorin affects the expression of SLC6A3 CTD PMID:26475043 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Th tyrosine hydroxylase affects expression EXP albiflorin affects the expression of TH CTD PMID:26475043 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
amikacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression EXP Amikacin results in decreased expression of ABCC3 mRNA CTD PMID:27765674 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression EXP Amikacin results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Casr calcium-sensing receptor increases activity ISO Amikacin results in increased activity of CASR protein CTD PMID:19884751 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cat catalase decreases activity
multiple interactions
ISO Amikacin results in decreased activity of CAT protein
cefepime inhibits the reaction [Amikacin results in decreased activity of CAT protein]
CTD PMID:18781908, PMID:23416261 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Amikacin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Tyr tyrosinase decreases activity ISO Amikacin results in decreased activity of TYR protein CTD PMID:23416261 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
asperuloside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO asperuloside inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:16508180 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
calycosin-7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin increases expression ISO calycosin-7-O-beta-D-glucoside results in increased expression of EPO mRNA CTD PMID:21309574 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO calycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein
calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA
CTD PMID:21309574 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
cyanidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of and affects the localization of RELA protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:27983965 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO [cyanidin 3-O-glucoside results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:23735880 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of AKT1 protein] CTD PMID:21501596 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression ISO cyanidin 3-O-glucoside results in increased expression of AKT2 mRNA CTD PMID:30597948 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Avp arginine vasopressin multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of AVP mRNA] CTD PMID:31014900 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein]
cyanidin 3-O-glucoside results in increased expression of CASP3 mRNA
CTD PMID:24518827, PMID:30597948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression ISO cyanidin 3-O-glucoside results in increased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of CREM protein] CTD PMID:31014900 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of CYP11A1 protein] CTD PMID:31014900 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO cyanidin 3-O-glucoside results in decreased activity of CYP1A1 protein
cyanidin 3-O-glucoside results in increased expression of CYP1A1 mRNA
[cyanidin 3-O-glucoside results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
CTD PMID:23735880 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased secretion of FSHB protein] CTD PMID:31014900 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of FSHR mRNA] CTD PMID:31014900 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
affects binding
ISO [cyanidin 3-O-glucoside binds to FYN protein] which results in decreased activity of FYN protein; cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased activity of FYN protein] CTD PMID:21501596 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA CTD PMID:27818126 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of GNRH1 mRNA] CTD PMID:31014900 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
cyanidin 3-O-glucoside results in decreased expression of HIF1A protein
CTD PMID:24518827 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO cyanidin 3-O-glucoside results in increased expression of HMOX1 mRNA
[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein]
CTD PMID:24518827, PMID:26422990, PMID:27793764, PMID:27818126, PMID:27983965 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27793764 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of KISS1 mRNA] CTD PMID:31014900 NCBI chr13:50,529,506...50,537,603
Ensembl chr13:50,529,510...50,535,389
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO [cyanidin 3-O-glucoside co-treated with Cadmium Chloride] results in increased secretion of LHB protein CTD PMID:31014900 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAP2K4 protein] CTD PMID:21501596 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK1 protein] CTD PMID:21501596 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK3 protein] CTD PMID:21501596 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of MMP2 protein] CTD PMID:24518827 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
multiple interactions
EXP
ISO
cyanidin 3-O-glucoside results in increased activity of NFE2L2 protein
[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein
CTD PMID:27166148, PMID:27818126 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of NFKBIA protein modified form] CTD PMID:27793764, PMID:27983965 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:27983965 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO cyanidin 3-O-glucoside results in increased expression of NQO1 mRNA CTD PMID:26422990, PMID:27793764 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression ISO cyanidin 3-O-glucoside results in increased expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO cyanidin 3-O-glucoside results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of PRKACA protein] CTD PMID:31014900 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 mRNA]; cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 protein]
cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
CTD PMID:21501596, PMID:27793764 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO cyanidin 3-O-glucoside affects the localization of and results in decreased activity of RELA protein; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of and affects the localization of RELA protein]; cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein] CTD PMID:26422990, PMID:27983965 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sele selectin E multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:26422990, PMID:30611791 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of STAR protein] CTD PMID:31014900 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO cyanidin 3-O-glucoside results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in decreased abundance of Antioxidants]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in decreased abundance of Glutathione]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased abundance of Thromboxane B2]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of NFKBIA protein modified form]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27793764, PMID:27818126, PMID:30611791 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA] CTD PMID:26422990 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
daidzein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions
EXP daidzin results in increased expression of ACHE mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of ACHE mRNA]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of and results in increased activity of ACHE protein]; daidzin results in increased expression of and results in increased activity of ACHE protein
CTD PMID:31034797 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]; daidzin inhibits the reaction [ALDH2 protein results in increased oxidation of propionaldehyde] CTD PMID:21349255 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of BDNF protein] CTD PMID:32450180 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:75,693,216...75,706,069
Ensembl chr 1:75,693,232...75,706,069
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668
JBrowse link
G Cat catalase multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased activity of CAT protein] CTD PMID:32450180 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:60,848,161...60,882,470
Ensembl chr11:60,848,131...60,882,379
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,708,915...38,781,598
Ensembl chr12:38,709,595...38,782,010
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:209,097,894...209,116,978
Ensembl chr 2:209,097,927...209,116,965
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:10,846,493...10,882,560
Ensembl chr 9:10,846,596...10,882,649
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:205,706,023...205,743,676
Ensembl chr 1:205,706,468...205,743,653
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:90,383,111...90,393,476
Ensembl chr10:90,383,813...90,393,317
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:62,845,054...62,860,361
Ensembl chr 4:62,844,971...62,860,446
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:31,734,297...31,736,115
Ensembl chr20:31,734,183...31,736,212
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:84,328,114...84,338,486
Ensembl chr 1:84,328,114...84,338,483
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of HMOX1 protein] CTD PMID:32450180 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:187,302,192...187,311,677
Ensembl chr 2:187,302,192...187,311,676
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:152,892,388...152,972,196
Ensembl chr 4:152,892,388...152,972,201
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:198,301,666...198,311,787
Ensembl chr 2:198,303,168...198,311,785
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:256,585,410...256,734,727
Ensembl chr 1:256,585,410...256,734,730
JBrowse link
G Nefh neurofilament heavy increases expression EXP daidzin results in increased expression of NEFH mRNA; daidzin results in increased expression of NEFH protein CTD PMID:31034797 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light increases expression EXP daidzin results in increased expression of NEFL mRNA; daidzin results in increased expression of NEFL protein CTD PMID:31034797 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Pgr progesterone receptor increases expression ISO daidzin results in increased expression of PGR protein CTD PMID:17142977 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression
multiple interactions
EXP daidzin results in increased expression of PRIMA1 mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of PRIMA1 mRNA]
CTD PMID:31034797 NCBI chr 6:127,075,954...127,127,985
Ensembl chr 6:127,075,954...127,127,413
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:38,680,583...38,741,570
Ensembl chr 3:38,682,146...38,741,113
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:74,783,009...74,902,049
Ensembl chr 7:74,783,019...74,901,997
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:98,512,663...98,521,736
Ensembl chr 1:98,512,625...98,521,706
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:77,052,445...77,161,964
Ensembl chr 5:77,052,484...77,157,915
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:72,443,750...72,462,293
Ensembl chr 1:72,443,758...72,461,547
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:125,437,767...125,601,408
Ensembl chr 6:125,437,775...125,590,049
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 3:82,081,838...82,097,064
Ensembl chr 3:82,081,906...82,097,056
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,231,180...9,257,821
Ensembl chr 5:9,230,984...9,257,934
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in increased expression of VEGFA protein] CTD PMID:32450180 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
etoposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
multiple interactions
increases expression
ISO ABCB1 exon polymorphism affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide
Etoposide results in increased expression of ABCB1 mRNA; Etoposide results in increased expression of ABCB1 protein
CTD PMID:12969965, PMID:15239124, PMID:19047049, PMID:19562670, PMID:27570640, PMID:27840903 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance
multiple interactions
decreases uptake
increases expression
ISO ABCC1 protein affects the susceptibility to Etoposide
ABCC1 protein results in decreased susceptibility to Etoposide; ABCC1 results in decreased susceptibility to Etoposide
[GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; hesperetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]
ABCC1 protein results in decreased uptake of Etoposide
Etoposide results in increased expression of ABCC1 mRNA
Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]
CTD PMID:7954421, PMID:8968083, PMID:9334814, PMID:10348353, PMID:10856430, PMID:10900222, PMID:11778547, PMID:15180633, PMID:15460906, PMID:15617835, PMID:15999103, PMID:16156793, PMID:16217747 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
multiple interactions
ISO ABCC2 protein affects the transport of Etoposide
Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]
CTD PMID:15751272, PMID:15849751 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases response to substance ISO ABCC3 protein results in decreased susceptibility to Etoposide CTD PMID:15884115 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide] CTD PMID:21712253 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Etoposide results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Abra actin-binding Rho activating protein increases expression ISO Etoposide results in increased expression of ABRA mRNA CTD PMID:29397400 NCBI chr 7:80,792,615...80,796,683
Ensembl chr 7:80,792,600...80,796,670
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain affects response to substance ISO ACADM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression ISO Etoposide results in increased expression of ACE2 mRNA CTD PMID:29397400 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Aco1 aconitase 1 increases expression ISO Etoposide results in increased expression of ACO1 mRNA CTD PMID:25270620 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 affects response to substance ISO ACSL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression ISO Etoposide results in decreased expression of ACTA1 mRNA CTD PMID:29397400 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Agrn agrin increases expression ISO Etoposide results in increased expression of AGRN mRNA CTD PMID:17374387 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 affects response to substance ISO AHCYL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
JBrowse link
G Ahi1 Abelson helper integration site 1 increases expression ISO Etoposide results in increased expression of AHI1 protein alternative form CTD PMID:19379585 NCBI chr 1:16,478,127...16,601,769
Ensembl chr 1:16,478,127...16,601,769
JBrowse link
G Akap12 A-kinase anchoring protein 12 affects response to substance ISO AKAP12 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases response to substance
increases phosphorylation
multiple interactions
ISO AKT1 protein modified form results in increased susceptibility to Etoposide
Etoposide results in increased phosphorylation of AKT1 protein
Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein; pepstatin inhibits the reaction [AKT1 protein modified form results in increased susceptibility to Etoposide]; PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:17699715, PMID:17935137, PMID:27769712 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Etoposide results in increased expression of ALAS1 mRNA CTD PMID:25270620 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Etoposide CTD PMID:15905174 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C affects response to substance
multiple interactions
ISO ALDOC protein affects the susceptibility to Etoposide
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein
CTD PMID:16217747, PMID:29733421 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alpg alkaline phosphatase, germ cell affects response to substance ISO ALPG protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:94,164,667...94,184,972
Ensembl chr 9:94,178,221...94,181,010
JBrowse link
G Alpp alkaline phosphatase, placental affects response to substance ISO ALPP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Ank1 ankyrin 1 increases expression ISO Etoposide results in increased expression of ANK1 mRNA CTD PMID:29397400 NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Ankrd10 ankyrin repeat domain 10 decreases expression ISO Etoposide results in decreased expression of ANKRD10 mRNA CTD PMID:21527772 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Ankrd27 ankyrin repeat domain 27 decreases expression ISO Etoposide results in decreased expression of ANKRD27 mRNA CTD PMID:25270620 NCBI chr 1:91,857,048...91,958,763
Ensembl chr 1:91,857,057...91,958,763
JBrowse link
G Ankrd28 ankyrin repeat domain 28 affects response to substance ISO ANKRD28 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
JBrowse link
G Anxa4 annexin A4 increases expression ISO Etoposide results in increased expression of ANXA4 mRNA CTD PMID:17374387 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Etoposide results in increased expression of APAF1 mRNA CTD PMID:25270620 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases response to substance ISO APEX1 protein results in decreased susceptibility to Etoposide CTD PMID:20856196 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression ISO Etoposide results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 1:88,897,525...88,908,750
Ensembl chr 1:88,897,532...88,908,750
JBrowse link
G Aqp1 aquaporin 1 decreases expression ISO Etoposide results in decreased expression of AQP1 mRNA CTD PMID:25270620 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ar androgen receptor multiple interactions
increases degradation
ISO calpain inhibitor 2 inhibits the reaction [Etoposide results in increased degradation of AR protein]; CAST inhibits the reaction [Etoposide results in increased degradation of AR protein]; Etoposide inhibits the reaction [Androgens results in increased activity of AR protein]; Etoposide inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18726991, PMID:28377212, PMID:30818834 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Areg amphiregulin increases expression
decreases expression
ISO Etoposide results in increased expression of AREG mRNA; Etoposide results in increased expression of AREG protein
Etoposide results in decreased expression of AREG mRNA
CTD PMID:15228094, PMID:25270620 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg2 arginase 2 decreases expression ISO Etoposide results in decreased expression of ARG2 mRNA CTD PMID:29397400 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Etoposide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases response to substance ISO ARIH1 mutant form results in increased susceptibility to Etoposide CTD PMID:25624349 NCBI chr 8:64,166,359...64,268,555
Ensembl chr 8:64,166,360...64,268,555
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases response to substance
decreases expression
ISO ARL6IP5 protein results in increased susceptibility to Etoposide
Etoposide results in decreased expression of ARL6IP5
CTD PMID:19492242 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arsa arylsulfatase A decreases expression ISO Etoposide results in decreased expression of ARSA mRNA CTD PMID:25270620 NCBI chr 7:130,446,644...130,452,632
Ensembl chr 7:130,446,668...130,451,283
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects response to substance ISO ASAH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Etoposide results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:12663670 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Etoposide results in decreased expression of ATF4 mRNA CTD PMID:25270620 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Etoposide results in increased phosphorylation of and results in increased activity of ATM protein
Etoposide results in increased phosphorylation of and affects the localization of ATM protein; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of and affects the localization of ATM protein]
CTD PMID:22242153, PMID:26259609 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp13a4 ATPase 13A4 decreases expression ISO Etoposide results in decreased expression of ATP13A4 mRNA CTD PMID:25270620 NCBI chr11:74,833,824...74,968,160
Ensembl chr11:74,834,050...74,968,336
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects response to substance ISO ATP1A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO Etoposide results in decreased expression of ATP1A2 mRNA CTD PMID:29397400 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 increases expression ISO Etoposide results in increased expression of ATP1B4 mRNA CTD PMID:29397400 NCBI chr  X:124,631,544...124,652,520
Ensembl chr  X:124,631,881...124,652,975
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Etoposide results in decreased expression of ATP5O protein CTD PMID:29733421 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 affects response to substance ISO ATP6V0A4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:65,736,585...65,821,916
Ensembl chr 4:65,736,585...65,818,521
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Etoposide results in decreased expression of ATP6V1A protein
CTD PMID:29733421 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Atp7a ATPase copper transporting alpha decreases response to substance ISO ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atr ATR serine/threonine kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of ATR protein CTD PMID:22242153 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Etoposide results in decreased expression of ATXN1 mRNA CTD PMID:24211769 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Aurka aurora kinase A decreases expression ISO Etoposide results in decreased expression of AURKA mRNA CTD PMID:25270620 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Avpi1 arginine vasopressin-induced 1 affects response to substance ISO AVPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:261,365,590...261,371,519
Ensembl chr 1:261,365,590...261,371,508
JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases expression ISO Etoposide results in increased expression of AVPR1A mRNA CTD PMID:29397400 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Etoposide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bace2 beta-secretase 2 affects response to substance ISO BACE2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:37,798,397...37,880,624
Ensembl chr11:37,798,370...37,880,821
JBrowse link
G Bag2 BAG cochaperone 2 affects response to substance ISO BAG2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases response to substance
affects response to substance
multiple interactions
affects expression
ISO Etoposide results in increased activity of BAK1 protein
BAK1 protein results in increased susceptibility to Etoposide
BAK1 protein affects the susceptibility to Etoposide
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
Etoposide affects the expression of BAK1 protein
CTD PMID:15215046, PMID:16077961, PMID:17688235, PMID:21745461 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects response to substance ISO BAMBI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases folding
affects response to substance
ISO [ABT-737 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [Cisplatin co-treated with Etoposide] affects the localization of BAX protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]; Etoposide results in increased activity of and affects the localization of BAX protein; Etoposide results in increased cleavage of and results in increased expression of BAX protein; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] affects the localization of BAX protein]; nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein]
Etoposide results in increased expression of BAX mRNA; Etoposide results in increased expression of BAX protein
BAX protein affects the susceptibility to Etoposide
CTD PMID:9815696, PMID:10620629, PMID:15131059, PMID:16077961, PMID:16120219, PMID:18676776, PMID:21527772, PMID:21745461, PMID:21880625, PMID:29397400 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions
affects response to substance
ISO Etoposide results in increased expression of BBC3 mRNA; Etoposide results in increased expression of BBC3 protein
entinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]; Etoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]
BBC3 protein affects the susceptibility to Etoposide
CTD PMID:20477944, PMID:21801448, PMID:25699604 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [Etoposide co-treated with Ciprofloxacin] results in decreased expression of BCL2 protein; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of BCL2 mRNA; Etoposide results in decreased expression of BCL2 protein
[G(M3) Ganglioside results in increased expression of BCL2 protein] which results in decreased susceptibility to Etoposide; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]
CTD PMID:8840993, PMID:9815696, PMID:12063570, PMID:15917659, PMID:16571667, PMID:19408126 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects expression
decreases response to substance
ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]
Etoposide affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Etoposide
CTD PMID:8840993, PMID:10620629, PMID:11468182, PMID:15215046, PMID:15917659, PMID:19047049 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases response to substance ISO BCL2L2 results in decreased susceptibility to Etoposide CTD PMID:14973057 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:56,834,363...56,840,058
Ensembl chr10:56,834,364...56,839,437
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions
ISO Etoposide results in increased expression of BDNF mRNA
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]
CTD PMID:20573984 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression
increases cleavage
ISO CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA] CTD PMID:19426747, PMID:21801448 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bik BCL2-interacting killer increases response to substance ISO BIK protein results in increased susceptibility to Etoposide CTD PMID:16007125 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Bin1 bridging integrator 1 increases response to substance ISO BIN1 protein results in increased susceptibility to Etoposide CTD PMID:21447800 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Bin3 bridging integrator 3 affects response to substance ISO BIN3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:51,799,339...51,818,697
Ensembl chr15:51,779,839...51,818,699
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance
decreases response to substance
increases expression
ISO BIRC2 protein affects the susceptibility to Etoposide
BIRC2 protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of BIRC2 mRNA
CTD PMID:10815900, PMID:14970392, PMID:15050749, PMID:16217747 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases response to substance
decreases expression
multiple interactions
ISO BIRC3 protein results in decreased susceptibility to Etoposide
Etoposide results in decreased expression of BIRC3 mRNA
[Etoposide co-treated with KN 62] results in decreased expression of BIRC3 protein
CTD PMID:14666661, PMID:15050749, PMID:16120219 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases response to substance
increases expression
ISO [FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; BIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Estradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]
BIRC5 protein results in decreased susceptibility to Etoposide
CTD PMID:15917659, PMID:16322251, PMID:16364925, PMID:16382892, PMID:19211844, PMID:19426747 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Etoposide CTD PMID:17437058 NCBI chr 3:176,438,335...176,443,864
Ensembl chr 3:176,439,199...176,443,195
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Etoposide results in decreased expression of BLM mRNA CTD PMID:24211769 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions
increases expression
decreases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]; pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of BRCA1 protein]
Etoposide results in increased expression of BRCA1 protein
Etoposide results in decreased expression of BRCA1 mRNA
CTD PMID:15607317, PMID:16417649, PMID:26259609 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Etoposide results in increased expression of BSCL2 mRNA CTD PMID:22003191, PMID:25270620 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions
increases expression
ISO TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]
Etoposide results in increased expression of BTG2 mRNA; Etoposide results in increased expression of BTG2 protein
CTD PMID:21382384, PMID:22003191, PMID:24211769, PMID:27358234 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btg3 BTG anti-proliferation factor 3 decreases expression ISO Etoposide results in decreased expression of BTG3 mRNA CTD PMID:24211769 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Etoposide results in decreased expression of BUB1 mRNA CTD PMID:16120219 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Etoposide results in decreased expression of BUB1B mRNA CTD PMID:16120219 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Etoposide CTD PMID:25354864 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G Cab39 calcium binding protein 39 decreases expression ISO Etoposide results in decreased expression of CAB39 mRNA CTD PMID:17374387 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects response to substance ISO CADPS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:50,326,447...50,861,161
Ensembl chr 4:50,326,442...50,860,756
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
decreases response to substance
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CALCA protein results in decreased susceptibility to Etoposide] CTD PMID:16222118 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm1 calmodulin 1 increases expression ISO Etoposide results in increased expression of CALM1 mRNA CTD PMID:29397400 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of CARD10 mRNA] CTD PMID:19426747 NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
JBrowse link
G Casp2 caspase 2 increases expression
increases splicing
ISO Etoposide results in increased expression of CASP2 mRNA alternative form
Etoposide results in increased splicing of CASP2 mRNA
CTD PMID:14757846 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 affects expression
increases cleavage
multiple interactions
increases activity
increases expression
ISO
EXP
Etoposide affects the expression of CASP3 protein
Etoposide results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [Etoposide co-treated with Mifepristone] results in increased activity of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; Dehydroascorbic Acid promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Silver results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased expression of CASP3 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Metoclopramide inhibits the reaction [Etoposide results in increased activity of CASP3 protein]
CTD PMID:8840993, PMID:10759716, PMID:12871656, PMID:15215046, PMID:15924153, PMID:16014620, PMID:16192531, PMID:16364925, PMID:16545138, PMID:16844113, PMID:16951922, PMID:17516866, PMID:17935137, PMID:18056177, PMID:18649362, PMID:19047049, PMID:19408126, PMID:19662097, PMID:19760634, PMID:20299546, PMID:20573984, PMID:21617849, PMID:21745461, PMID:21745629, PMID:21801448, PMID:21880625, PMID:22275372, PMID:22302033, PMID:23144690, PMID:25447644, PMID:26259609, PMID:29027213, PMID:30217652, PMID:30890322 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
CTD PMID:18056177, PMID:18649362, PMID:20299546, PMID:21801448, PMID:22275372, PMID:22302033, PMID:26259609 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance
increases cleavage
increases activity
decreases response to substance
ISO 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; acetyl-leucyl-glutamyl-histidyl-aspartal inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP8 protein; Etoposide results in increased expression of and results in increased cleavage of CASP8 protein; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]
CASP8 protein results in increased susceptibility to Etoposide
CTD PMID:15475000, PMID:21745461, PMID:21801448, PMID:22010212 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
affects expression
ISO [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Etoposide results in increased cleavage of and results in increased activity of CASP9 protein; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
Etoposide affects the expression of CASP9 protein
CTD PMID:12925536, PMID:15215046, PMID:16364925, PMID:16799960, PMID:17935137, PMID:18056177, PMID:18676776, PMID:21324178, PMID:21745461, PMID:21801448 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casq2 calsequestrin 2 decreases expression ISO Etoposide results in decreased expression of CASQ2 mRNA CTD PMID:29397400 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Cast calpastatin multiple interactions ISO CAST inhibits the reaction [Etoposide results in increased degradation of AR protein] CTD PMID:18726991 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase increases response to substance
increases activity
ISO CAT results in increased susceptibility to Etoposide
Etoposide results in increased activity of CAT protein
CTD PMID:21689642, PMID:25451571 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc51 coiled-coil domain containing 51 decreases expression ISO Etoposide results in decreased expression of CCDC51 mRNA CTD PMID:24211769 NCBI chr 8:117,812,091...117,830,848
Ensembl chr 8:117,812,099...117,830,868
JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases response to substance
decreases response to substance
ISO CCDC6 results in increased susceptibility to Etoposide
CCDC6 results in decreased susceptibility to Etoposide
CTD PMID:22363533, PMID:22655027 NCBI chr20:19,729,005...19,825,219
Ensembl chr20:19,732,894...19,825,150
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Etoposide results in increased expression of CCL3 protein CTD PMID:10540334 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO Etoposide affects the expression of and affects the localization of CCNA2 protein
Etoposide results in decreased expression of CCNA2 mRNA; Etoposide results in decreased expression of CCNA2 protein
CTD PMID:16120219, PMID:17390037 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Etoposide results in decreased expression of CCNB1 mRNA; Etoposide results in decreased expression of CCNB1 protein CTD PMID:16120219 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Etoposide results in increased expression of CCND1 mRNA CTD PMID:16120219 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccng1 cyclin G1 increases expression ISO Etoposide results in increased expression of CCNG1 mRNA CTD PMID:25270620 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Etoposide results in increased expression of CCNG2 mRNA CTD PMID:18754885 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Etoposide results in increased expression of CCS mRNA CTD PMID:21527772 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd274 CD274 molecule increases expression ISO Etoposide results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd40lg CD40 ligand multiple interactions
decreases response to substance
ISO CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]
CD40LG protein results in decreased susceptibility to Etoposide
CTD PMID:16545138 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd44 CD44 molecule (Indian blood group) affects response to substance
multiple interactions
ISO CD44 protein affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]
CTD PMID:15215046, PMID:19047049 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) affects response to substance ISO CD55 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd59 CD59 molecule multiple interactions ISO [Cisplatin co-treated with Etoposide] results in decreased expression of CD59 protein CTD PMID:21826740 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Etoposide results in decreased expression of CDC25A mRNA CTD PMID:24211769 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Etoposide results in decreased expression of CDC25C mRNA CTD PMID:16120219 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc42bpg CDC42 binding protein kinase gamma increases expression ISO Etoposide results in increased expression of CDC42BPG mRNA CTD PMID:25270620 NCBI chr 1:221,673,334...221,693,518
Ensembl chr 1:221,673,590...221,693,518
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Etoposide results in decreased expression of CDC45 mRNA CTD PMID:16120219 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Etoposide results in decreased expression of CDC6 mRNA CTD PMID:16120219 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression
affects response to substance
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein]
CDK2 protein affects the susceptibility to Etoposide
CTD PMID:16217747, PMID:16417649, PMID:20149834 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; entinostat promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [entinostat results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of CDKN1A protein]; KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of CDKN1A protein]
Etoposide results in increased expression of CDKN1A mRNA; Etoposide results in increased expression of CDKN1A protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; Etoposide promotes the reaction [Niacin deficiency results in increased expression of CDKN1A protein]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]
CTD PMID:14601052, PMID:16120219, PMID:16882877, PMID:17516866, PMID:21212465, PMID:21526190, PMID:21527772, PMID:21617849, PMID:21801448, PMID:21880625, PMID:23690541, PMID:24067374, PMID:24211769, PMID:25078064, PMID:25699604, PMID:25914138, PMID:26055805, PMID:27129209, PMID:27358234, PMID:27982581, PMID:29471073 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO Etoposide results in increased expression of CDKN1B protein
wortmannin promotes the reaction [Etoposide results in increased expression of CDKN1B protein]
CTD PMID:17935137 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
EXP
ISO
Etoposide results in increased expression of CDKN2A mRNA
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]
CTD PMID:21526190, PMID:23690541 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Etoposide results in decreased expression of CDKN3 mRNA CTD PMID:16120219 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Etoposide results in increased expression of CEACAM1 mRNA CTD PMID:17374387 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
increases degradation
ISO Etoposide results in decreased expression of CEBPA mRNA; Etoposide results in decreased expression of CEBPA protein
Etoposide results in increased degradation of CEBPA protein
CTD PMID:19662097 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpz CCAAT/enhancer binding protein zeta decreases expression ISO Etoposide results in decreased expression of CEBPZ mRNA CTD PMID:17374387 NCBI chr 6:1,516,804...1,534,488
Ensembl chr 6:1,516,804...1,534,488
JBrowse link
G Cel carboxyl ester lipase increases expression ISO Etoposide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cenpf centromere protein F decreases expression ISO Etoposide results in decreased expression of CENPF mRNA CTD PMID:16120219 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cercam cerebral endothelial cell adhesion molecule increases expression ISO Etoposide results in increased expression of CERCAM mRNA CTD PMID:25270620 NCBI chr 3:8,421,116...8,444,743
Ensembl chr 3:8,430,829...8,444,851
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Etoposide results in increased expression of CES1D mRNA CTD PMID:25270620 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Etoposide results in increased expression of CFLAR protein CTD PMID:14601052 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression ISO Etoposide results in increased expression of CGREF1 mRNA CTD PMID:25270620 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO Etoposide results in decreased expression of CHAC1 mRNA CTD PMID:25270620 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO Etoposide results in decreased expression of CHAF1A mRNA CTD PMID:24211769 NCBI chr 9:11,000,869...11,027,631
Ensembl chr 9:11,001,129...11,027,506
JBrowse link
G Chek1 checkpoint kinase 1 affects response to substance
multiple interactions
ISO CHEK1 protein affects the susceptibility to Etoposide
TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]
CTD PMID:18698031 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions
ISO Etoposide results in increased phosphorylation of CHEK2 protein
4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]
CTD PMID:21186793, PMID:22242153, PMID:26259609 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chi3l1 chitinase 3 like 1 decreases response to substance ISO CHI3L1 results in decreased susceptibility to Etoposide CTD PMID:20506295 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases response to substance ISO CIAPIN1 protein results in decreased susceptibility to Etoposide CTD PMID:18389626 NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
JBrowse link
G Ckm creatine kinase, M-type decreases expression ISO Etoposide results in decreased expression of CKM mRNA CTD PMID:29397400 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 affects response to substance ISO CKMT1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO Etoposide results in decreased expression of COA7 mRNA CTD PMID:24211769 NCBI chr 5:127,925,726...127,936,516
Ensembl chr 5:127,925,726...127,936,509
JBrowse link
G Cobl cordon-bleu WH2 repeat protein decreases expression ISO Etoposide results in decreased expression of COBL mRNA CTD PMID:25270620 NCBI chr14:92,341,949...92,497,169
Ensembl chr14:92,342,957...92,577,936
JBrowse link
G Col15a1 collagen type XV alpha 1 chain affects response to substance ISO COL15A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:62,840,360...62,950,240 JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO Etoposide results in decreased expression of COL4A1 mRNA CTD PMID:25270620 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col9a3 collagen type IX alpha 3 chain affects response to substance ISO COL9A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:176,102,287...176,124,839
Ensembl chr 3:176,102,351...176,124,306
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO Etoposide results in decreased expression of COX6A2 mRNA CTD PMID:29397400 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 affects response to substance ISO CPS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Etoposide results in decreased expression of CPT2 mRNA CTD PMID:24211769 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO Etoposide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein; HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein] CTD PMID:20573984 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator affects response to substance ISO CREM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crip2 cysteine-rich protein 2 increases expression ISO Etoposide results in increased expression of CRIP2 mRNA CTD PMID:25270620 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 affects response to substance ISO CSGALNACT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link
G Cth cystathionine gamma-lyase affects response to substance ISO CTH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Etoposide results in decreased expression of CXCL12 mRNA; Etoposide results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Etoposide affects the localization of CYCS protein CTD PMID:10759716 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO Etoposide results in increased expression of CYP1A1 mRNA; Etoposide results in increased expression of CYP1A1 protein
Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]
CTD PMID:29471073, PMID:31542801 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Etoposide results in increased expression of CYP1A2 mRNA CTD PMID:31542801 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases response to substance ISO CYP26A1 protein results in decreased susceptibility to Etoposide CTD PMID:15703382 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Etoposide results in increased expression of CYP27B1 mRNA CTD PMID:17716971 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression ISO Etoposide results in increased expression of CYP2C55 mRNA CTD PMID:25270620 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO Etoposide results in increased expression of CYP2C29 mRNA CTD PMID:25270620 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression ISO Etoposide results in decreased expression of CYP2S1 mRNA CTD PMID:25270620 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects response to substance
decreases methylation
ISO CYP3A5 gene polymorphism affects the susceptibility to Etoposide
CYP3A5 protein results in decreased methylation of Etoposide
CTD PMID:8114683, PMID:12969965 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyren cell cycle regulator of NHEJ affects localization ISO Etoposide affects the localization of CYREN protein alternative form CTD PMID:24610814 NCBI chr 4:62,391,770...62,397,162
Ensembl chr 4:62,391,770...62,396,035
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO Etoposide results in decreased expression of DBF4 mRNA CTD PMID:25270620 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Dbn1 drebrin 1 affects response to substance ISO DBN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dcaf4 DDB1 and CUL4 associated factor 4 increases expression ISO Etoposide results in increased expression of DCAF4 mRNA CTD PMID:25270620 NCBI chr 6:107,001,763...107,027,466
Ensembl chr 6:107,001,763...107,027,456
JBrowse link
G Dct dopachrome tautomerase affects response to substance ISO DCT protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects response to substance ISO DDIT4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Etoposide results in increased expression of DDR1 mRNA CTD PMID:25270620 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Des desmin decreases expression ISO Etoposide results in decreased expression of DES mRNA CTD PMID:29397400 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance ISO DKK3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Dmd dystrophin affects response to substance
decreases expression
ISO DMD protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of DMD mRNA
CTD PMID:16217747, PMID:29397400 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 decreases expression ISO Etoposide results in decreased expression of DMRT1 mRNA CTD PMID:25270620 NCBI chr 1:243,477,403...243,582,629
Ensembl chr 1:243,477,493...243,582,629
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases response to substance EXP
ISO
DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases response to substance ISO DNMT3B protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions ISO Etoposide promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Etoposide results in decreased expression of DPYSL2 protein CTD PMID:29733421 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Etoposide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 1:211,423,022...211,438,533
Ensembl chr 1:211,423,022...211,438,531
JBrowse link
G Dusp2 dual specificity phosphatase 2 affects response to substance ISO DUSP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Dusp4 dual specificity phosphatase 4 affects response to substance
increases expression
ISO DUSP4 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of DUSP4 mRNA
CTD PMID:16217747, PMID:29397400 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednrb endothelin receptor type B decreases expression ISO Etoposide results in decreased expression of EDNRB mRNA CTD PMID:25270620 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Efs embryonal Fyn-associated substrate increases expression ISO Etoposide results in increased expression of EFS mRNA CTD PMID:25270620 NCBI chr15:33,579,952...33,590,217
Ensembl chr15:33,578,381...33,589,522
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide CTD PMID:16969495 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfl8 EGF-like-domain, multiple 8 affects response to substance ISO EGFL8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:4,378,205...4,380,959
Ensembl chr20:4,378,206...4,380,600
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Etoposide results in decreased expression of EGFR mRNA; Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein increases expression ISO Etoposide results in increased expression of EI24 mRNA CTD PMID:17374387 NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO Etoposide results in decreased expression of EIF2S2 mRNA CTD PMID:25270620 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases response to substance ISO EIF3A results in increased susceptibility to Etoposide CTD PMID:21610145 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Etoposide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Emp2 epithelial membrane protein 2 affects response to substance ISO EMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Etoposide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G En2 engrailed homeobox 2 affects response to substance ISO EN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:438,668...444,508
Ensembl chr 4:438,668...444,501
JBrowse link
G Eno1 enolase 1 decreases expression ISO Etoposide results in decreased expression of ENO1 protein CTD PMID:29733421 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression ISO Etoposide results in decreased expression of ENTPD2 mRNA CTD PMID:25270620 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 affects response to substance ISO EPB41L3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384, PMID:25270620 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Epm2aip1 EPM2A interacting protein 1 increases expression ISO Etoposide results in increased expression of EPM2AIP1 mRNA CTD PMID:17374387 NCBI chr 8:119,524,039...119,531,387
Ensembl chr 8:119,524,039...119,531,387
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein results in increased susceptibility to [Organoplatinum Compounds co-treated with Etoposide] CTD PMID:18403296 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
decreases response to substance
affects response to substance
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Etoposide]
Etoposide results in decreased expression of ERBB2 mRNA
ERBB2 protein results in decreased susceptibility to Etoposide; ERBB2 results in decreased susceptibility to Etoposide
ERBB2 protein affects the susceptibility to Etoposide
CTD PMID:10327070, PMID:15228094, PMID:21712253, PMID:25866362 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 affects response to substance
decreases expression
ISO ERBB3 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of ERBB3 mRNA
CTD PMID:15228094, PMID:16217747, PMID:29397400 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO Etoposide results in decreased expression of ERBB4 mRNA CTD PMID:15228094 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Ereg epiregulin increases expression ISO Etoposide results in increased expression of EREG mRNA CTD PMID:15228094 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope affects response to substance ISO ERVFRD-1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Etoposide inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases response to substance
multiple interactions
ISO ESR2 protein results in increased susceptibility to Etoposide
TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]
CTD PMID:20623183 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 affects response to substance ISO ESRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:24,576,988...24,631,758
Ensembl chr 5:24,576,991...24,631,698
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO Etoposide inhibits the reaction [XCT790 results in decreased activity of ESRRA protein]; Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Etv6 ETS variant transcription factor 6 increases response to substance
increases mutagenesis
ISO ETV6 gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of ETV6 gene
CTD PMID:15217836, PMID:28624474 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO Etoposide results in increased expression of EXOC4 mRNA CTD PMID:25270620 NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994
JBrowse link
G F11r F11 receptor increases expression ISO Etoposide results in increased expression of F11R mRNA CTD PMID:29397400 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F2r coagulation factor II (thrombin) receptor affects response to substance ISO F2R protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Etoposide results in increased expression of F3 mRNA CTD PMID:12542493 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fads3 fatty acid desaturase 3 increases expression ISO Etoposide results in increased expression of FADS3 mRNA CTD PMID:21527772 NCBI chr 1:226,091,774...226,108,332
Ensembl chr 1:226,091,774...226,108,332
JBrowse link
G Fam171a1 family with sequence similarity 171, member A1 affects response to substance ISO FAM171A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:79,030,150...79,149,480
Ensembl chr17:79,031,423...79,085,076
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
ISO 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]; Etoposide results in increased expression of and affects the localization of FAS protein; Lithium inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]
Etoposide results in increased expression of FAS mRNA
Etoposide results in increased expression of FAS mRNA; Etoposide results in increased expression of FAS protein
CTD PMID:12513834, PMID:15475000, PMID:16192531, PMID:29397400 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
increases activity
ISO [linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; Nitric Oxide inhibits the reaction [Etoposide results in increased activity of FASLG promoter]
Etoposide results in increased expression of FASL mRNA
CTD PMID:10811113, PMID:12513834 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase increases expression ISO Etoposide results in increased expression of FASN mRNA CTD PMID:17089011 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbl fibrillarin affects localization ISO Etoposide analog affects the localization of FBL protein CTD PMID:10942594 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects response to substance ISO FDFT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdxr ferredoxin reductase increases expression ISO Etoposide results in increased expression of FDXR mRNA CTD PMID:17374387 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fhl1 four and a half LIM domains 1 affects response to substance ISO FHL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fhl2 four and a half LIM domains 2 decreases expression ISO Etoposide results in decreased expression of FHL2 mRNA CTD PMID:29397400 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Flnc filamin C increases expression ISO Etoposide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases response to substance
increases expression
multiple interactions
EXP
ISO
FOS protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of FOS
[Etoposide co-treated with Cyclic AMP] results in increased expression of FOS mRNA; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]
CTD PMID:10711420, PMID:18314485, PMID:23824011 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Etoposide results in increased expression of FOSL1 mRNA CTD PMID:25270620 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxf2 forkhead box F2 affects response to substance ISO FOXF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:34,150,417...34,156,450 JBrowse link
G Foxj2 forkhead box J2 decreases expression ISO Etoposide results in decreased expression of FOXJ2 mRNA CTD PMID:24211769 NCBI chr 4:155,653,446...155,679,815
Ensembl chr 4:155,653,718...155,679,793
JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation
multiple interactions
ISO Etoposide results in increased phosphorylation of FOXO1 protein
wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO1 protein]
CTD PMID:17935137 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 increases phosphorylation
increases response to substance
multiple interactions
ISO Etoposide results in increased phosphorylation of FOXO3 protein
FOXO3 protein results in increased susceptibility to Etoposide
[FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; Wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO3 protein]
CTD PMID:17935137, PMID:19211844 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression
ISO HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA] CTD PMID:20980392 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fut8 fucosyltransferase 8 affects response to substance ISO FUT8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase affects response to substance
decreases expression
ISO FYN protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of FYN mRNA
CTD PMID:16217747, PMID:25270620 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression ISO Etoposide results in decreased expression of FZD1 mRNA CTD PMID:24211769 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression ISO Etoposide results in decreased expression of FZD5 mRNA CTD PMID:25270620 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases response to substance
increases expression
ISO GADD45A protein results in increased susceptibility to Etoposide
Etoposide results in increased expression of GADD45A mRNA
CTD PMID:19003803, PMID:21527772, PMID:29397400, PMID:31542801 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein
Etoposide results in decreased expression of GANAB protein
CTD PMID:29733421 NCBI chr 1:225,096,558...225,116,384
Ensembl chr 1:225,096,598...225,116,378
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Etoposide results in increased expression of GAPDH protein CTD PMID:29733421 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression
ISO Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of GDF15 mRNA; Etoposide results in increased expression of GDF15 protein
CTD PMID:11895857, PMID:16120219, PMID:24211769, PMID:29397400 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases response to substance
ISO GJA1 protein affects the reaction [Simvastatin results in increased susceptibility to Etoposide]; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] CTD PMID:23978459 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression ISO Etoposide results in decreased expression of GJA5 mRNA CTD PMID:29397400 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gls2 glutaminase 2 increases expression ISO Etoposide results in increased expression of GLS2 mRNA CTD PMID:21527772, PMID:29397400 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO Etoposide results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr 7:116,632,496...116,635,543
Ensembl chr 7:116,632,506...116,634,293
JBrowse link
G Gpm6b glycoprotein m6b affects response to substance ISO GPM6B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Etoposide results in increased expression of GPNMB mRNA CTD PMID:29397400 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr37 G protein-coupled receptor 37 affects response to substance ISO GPR37 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Gpsm2 G-protein signaling modulator 2 affects response to substance ISO GPSM2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:211,480,120...211,528,096
Ensembl chr 2:211,480,400...211,527,919
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Etoposide results in increased expression of GPX1 mRNA CTD PMID:29397400 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Etoposide results in increased expression of GPX3 mRNA CTD PMID:25270620 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression ISO Etoposide results in increased expression of GRIA3 mRNA CTD PMID:25270620 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Etoposide results in decreased expression of GRPEL1 mRNA CTD PMID:24211769 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
ISO BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of GSK3B protein
CTD PMID:19408126 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm4 glutathione S-transferase mu 4 affects response to substance ISO GSTM4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
affects response to substance
ISO Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Ethacrynic Acid inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; verlukast inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]
GSTP1 gene polymorphism affects the susceptibility to Etoposide
CTD PMID:10900222, PMID:12969965, PMID:15999103 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 affects response to substance ISO GSTT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
decreases response to substance
increases phosphorylation
ISO
EXP
Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; palbociclib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; pifithrin promotes the reaction [Etoposide results in increased expression of H2AX protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide results in increased expression of H2AX protein]; TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione inhibits the reaction [Etoposide results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Bortezomib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Razoxane inhibits the reaction [Etoposide results in increased expression of H2AX protein]
H2AX protein results in decreased susceptibility to Etoposide
CTD PMID:17875725, PMID:20643100, PMID:20978201, PMID:21555580, PMID:21745461, PMID:22302033, PMID:25078064, PMID:26259609, PMID:32482060 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hal histidine ammonia lyase decreases expression ISO Etoposide results in decreased expression of HAL mRNA CTD PMID:25270620 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions
ISO Etoposide results in decreased expression of HAMP mRNA
Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]
CTD PMID:25270620, PMID:25633564 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Etoposide results in increased expression of HBEGF mRNA CTD PMID:15228094 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hbp1 HMG-box transcription factor 1 decreases expression ISO Etoposide results in decreased expression of HBP1 mRNA CTD PMID:24211769 NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625
JBrowse link
G Hdac4 histone deacetylase 4 affects response to substance ISO HDAC4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Heph hephaestin affects response to substance ISO HEPH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 multiple interactions
increases expression
ISO E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr10:62,007,150...62,010,774
Ensembl chr10:62,007,150...62,009,582
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO HIF1A mutant form inhibits the reaction [Oxygen deficiency results in decreased susceptibility to Etoposide] CTD PMID:23144690 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases activity
multiple interactions
decreases response to substance
ISO Etoposide results in increased activity of HIPK2 protein
HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein]; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]
HIPK2 results in decreased susceptibility to Etoposide
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]
CTD PMID:20573984, PMID:20980392 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific decreases expression ISO Etoposide results in decreased expression of HMCES mRNA CTD PMID:25270620 NCBI chr 4:119,841,088...119,864,115
Ensembl chr 4:119,815,139...119,864,114
JBrowse link
G Hmg20b high mobility group 20 B affects response to substance ISO HMG20B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:11,238,594...11,243,312
Ensembl chr 7:11,238,630...11,243,310
JBrowse link
G Hmga2 high mobility group AT-hook 2 affects response to substance ISO HMGA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmgb1 high mobility group box 1 increases secretion
decreases response to substance
ISO Etoposide results in increased secretion of HMGB1 protein
HMGB1 protein results in decreased susceptibility to Etoposide
CTD PMID:27807322 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 decreases expression ISO Etoposide results in decreased expression of HNRNPH2 protein CTD PMID:29733421 NCBI chr  X:105,417,603...105,423,531
Ensembl chr  X:105,419,285...105,422,861
JBrowse link
G Hoxa5 homeo box A5 affects response to substance ISO HOXA5 protein affects the susceptibility to Etoposide CTD PMID:16217747
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects response to substance ISO HSPA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Etoposide results in increased expression of HSPE1 protein CTD PMID:29733421 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 affects response to substance
increases response to substance
multiple interactions
ISO HTATIP2 protein affects the susceptibility to Etoposide
HTATIP2 protein results in increased susceptibility to Etoposide
HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]
CTD PMID:16217747, PMID:16799960 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 affects response to substance ISO HTR4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Ier5 immediate early response 5 increases expression ISO Etoposide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 increases expression ISO Etoposide results in increased expression of IGDCC4 mRNA CTD PMID:25270620 NCBI chr 8:70,591,561...70,627,329
Ensembl chr 8:70,603,249...70,624,925
JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects response to substance ISO IGF1R protein affects the susceptibility to Etoposide CTD PMID:15499378 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 affects response to substance ISO IGFBP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 decreases expression ISO Etoposide results in decreased expression of IGSF11 mRNA CTD PMID:25270620 NCBI chr11:64,286,691...64,421,248
Ensembl chr11:64,286,694...64,421,248
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects response to substance ISO IKBKB protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Etoposide results in increased expression of IL1B mRNA CTD PMID:18523641 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases response to substance
multiple interactions
ISO IL4 protein results in decreased susceptibility to Etoposide
[IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide
CTD PMID:10620629 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
ISO
EXP
(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased expression of IL6 mRNA]; (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased secretion of IL6 protein]
Etoposide results in increased expression of IL6 mRNA; Etoposide results in increased expression of IL6 protein
CTD PMID:15135310, PMID:17003255, PMID:18523641 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Etoposide results in increased expression of INKA2 mRNA CTD PMID:25270620 NCBI chr 2:208,170,652...208,187,088
Ensembl chr 2:208,170,652...208,185,965
JBrowse link
G Insig1 insulin induced gene 1 affects response to substance ISO INSIG1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Irs2 insulin receptor substrate 2 affects response to substance ISO IRS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO Etoposide results in decreased expression of IRX4 mRNA CTD PMID:29397400 NCBI chr 1:32,634,774...32,645,151
Ensembl chr 1:32,634,796...32,643,771
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Etoposide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 affects response to substance ISO ISG20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 decreases expression ISO Etoposide results in decreased expression of ISG20L2 mRNA CTD PMID:24211769 NCBI chr 2:187,302,192...187,311,677
Ensembl chr 2:187,302,192...187,311,676
JBrowse link
G Itga2b integrin subunit alpha 2b increases expression ISO Etoposide results in increased expression of ITGA2B mRNA CTD PMID:21527772 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itgb3 integrin subunit beta 3 increases response to substance ISO ITGB3 protein results in increased susceptibility to Etoposide CTD PMID:21332719 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 affects response to substance ISO ITPR1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Etoposide co-treated with Cyclic AMP] results in increased expression of JUN mRNA CTD PMID:10711420 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects response to substance ISO KCNAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:169,570,327...169,658,875
Ensembl chr 5:169,572,517...169,658,875
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 decreases expression ISO Etoposide results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases expression ISO Etoposide results in decreased expression of KCNN2 mRNA CTD PMID:29397400 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases response to substance
multiple interactions
increases response to substance
ISO KEAP1 protein results in decreased susceptibility to Etoposide
KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]
KEAP1 mRNA results in increased susceptibility to Etoposide
CTD PMID:22684020, PMID:26708503, PMID:27982581 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif1a kinesin family member 1A increases expression ISO Etoposide results in increased expression of KIF1A mRNA CTD PMID:21527772 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Etoposide results in decreased expression of KIF20A mRNA CTD PMID:24211769 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Etoposide results in decreased expression of KIF23 mRNA CTD PMID:25270620 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions
increases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein
Etoposide results in increased expression of KIT protein
CTD PMID:29733421 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO Etoposide results in increased expression of KLF5 mRNA CTD PMID:29397400 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Klf6 Kruppel-like factor 6 decreases expression ISO Etoposide results in decreased expression of KLF6 mRNA CTD PMID:24211769 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Klhl26 kelch-like family member 26 increases expression ISO Etoposide results in increased expression of KLHL26 mRNA CTD PMID:25270620 NCBI chr16:20,704,807...20,729,882
Ensembl chr16:20,704,807...20,729,882
JBrowse link
G Kmt2a lysine methyltransferase 2A increases response to substance
increases mutagenesis
increases cleavage
ISO KMT2A gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of KMT2A gene
Etoposide results in increased cleavage of KMT2A gene
CTD PMID:14712291, PMID:24086652, PMID:28624474 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Krt19 keratin 19 increases expression ISO Etoposide results in increased expression of KRT19 mRNA CTD PMID:29397400 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt80 keratin 80 increases expression ISO Etoposide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr 7:142,995,715...143,015,932
Ensembl chr 7:142,994,119...143,016,040
JBrowse link
G Kynu kynureninase affects response to substance ISO KYNU protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lancl1 LanC like 1 affects response to substance ISO LANCL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:74,018,192...74,048,098
Ensembl chr 9:74,014,656...74,048,244
JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression ISO Etoposide results in decreased expression of LAP3 mRNA CTD PMID:25270620 NCBI chr14:70,102,813...70,121,797
Ensembl chr14:70,102,814...70,121,797
JBrowse link
G Lcn2 lipocalin 2 increases response to substance EXP LCN2 protein results in increased susceptibility to Etoposide CTD PMID:19860839 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldb3 LIM domain binding 3 decreases expression ISO Etoposide results in decreased expression of LDB3 mRNA CTD PMID:29397400 NCBI chr16:10,878,348...10,943,016
Ensembl chr16:10,878,334...10,941,501
JBrowse link
G Lgals3 galectin 3 affects response to substance ISO LGALS3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals7 galectin 7 increases expression ISO Etoposide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 1:87,044,823...87,047,223
Ensembl chr 1:87,045,335...87,047,223
JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA
Etoposide results in decreased expression of LHX1 mRNA
CTD PMID:29733421 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Lhx2 LIM homeobox 2 decreases expression ISO Etoposide results in decreased expression of LHX2 mRNA CTD PMID:24211769 NCBI chr 3:22,628,674...22,658,447
Ensembl chr 3:22,640,545...22,658,446
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Etoposide results in increased expression of LIF mRNA CTD PMID:29397400 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Limch1 LIM and calponin homology domains 1 affects response to substance ISO LIMCH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G Lipa lipase A, lysosomal acid type affects response to substance ISO LIPA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects expression ISO Etoposide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC100911804 apolipoprotein L3-like increases expression ISO Etoposide results in increased expression of APOL8 mRNA CTD PMID:25270620 NCBI chr 7:118,979,230...118,986,699
Ensembl chr 7:118,979,608...118,983,984
JBrowse link
G LOC102548695 zinc finger protein 45-like decreases expression ISO Etoposide results in decreased expression of ZNF45 mRNA CTD PMID:24211769 NCBI chr 1:81,158,743...81,173,245
Ensembl chr 1:81,159,107...81,163,689
JBrowse link
G LOC498368 similar to RIKEN cDNA 0610040J01 affects response to substance ISO C4ORF19 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:46,050,752...46,134,770
Ensembl chr14:46,050,750...46,054,022
JBrowse link
G LOC683674 similar to Protein C7orf26 homolog decreases expression ISO Etoposide results in decreased expression of C7ORF26 mRNA CTD PMID:24211769 NCBI chr12:13,299,651...13,313,733
Ensembl chr12:13,299,859...13,313,358
JBrowse link
G Lrrc47 leucine rich repeat containing 47 decreases expression ISO Etoposide results in decreased expression of LRRC47 mRNA CTD PMID:24211769 NCBI chr 5:171,297,850...171,307,682
Ensembl chr 5:171,297,850...171,307,682
JBrowse link
G Ltbr lymphotoxin beta receptor multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of LTBR mRNA] CTD PMID:19426747 NCBI chr 4:157,822,838...157,829,291
Ensembl chr 4:157,822,840...157,829,241
JBrowse link
G Lxn latexin increases response to substance ISO LXN protein results in increased susceptibility to Etoposide CTD PMID:25341047 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Ly6e lymphocyte antigen 6 family member E affects response to substance ISO LY6E protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects response to substance ISO MACF1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:141,039,455...141,363,524
Ensembl chr 5:141,039,468...141,363,524
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 increases expression ISO Etoposide results in increased expression of MAN2B1 mRNA CTD PMID:25270620 NCBI chr19:26,196,797...26,216,981
Ensembl chr19:26,196,837...26,216,267
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO Etoposide results in increased expression of MAP2K3 mRNA CTD PMID:17374387 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Etoposide results in decreased expression of MAP3K5 mRNA CTD PMID:17374387 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map7 microtubule-associated protein 7 affects response to substance ISO MAP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:15,620,665...15,748,203
Ensembl chr 1:15,620,653...15,748,203
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein] CTD PMID:16014620, PMID:19720055, PMID:26046675 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 increases activity
affects response to substance
multiple interactions
ISO Etoposide results in increased activity of MAPK12 protein
MAPK12 protein affects the susceptibility to Etoposide
[MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide
CTD PMID:21878638 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein] CTD PMID:16014620, PMID:19720055, PMID:26046675 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions
increases phosphorylation
ISO (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased phosphorylation of MAPKAPK2 protein] CTD PMID:17003255 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Matn2 matrilin 2 affects response to substance ISO MATN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:72,985,832...73,210,093
Ensembl chr 7:72,985,495...73,207,695
JBrowse link
G Mbp myelin basic protein affects response to substance ISO MBP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Etoposide results in increased expression of MCAM mRNA CTD PMID:25270620 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
decreases expression
ISO wortmannin promotes the reaction [Etoposide results in decreased expression of MCL1 protein] CTD PMID:17935137 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Etoposide results in decreased expression of MCM10 mRNA CTD PMID:24211769 NCBI chr17:77,224,218...77,245,486
Ensembl chr17:77,224,112...77,246,478
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Etoposide results in decreased expression of MCM2 mRNA CTD PMID:16120219 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Etoposide results in decreased expression of MCM6 mRNA CTD PMID:16120219 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Etoposide results in decreased expression of MCM7 mRNA CTD PMID:16120219 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor decreases expression ISO Etoposide results in decreased expression of MCM8 mRNA CTD PMID:16120219 NCBI chr 3:125,470,499...125,500,795
Ensembl chr 3:125,470,551...125,500,795
JBrowse link
G Mdfic MyoD family inhibitor domain containing affects response to substance ISO MDFIC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:42,202,546...42,282,499
Ensembl chr 4:42,202,838...42,282,496
JBrowse link
G Mdh2 malate dehydrogenase 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein CTD PMID:29733421 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
decreases expression
increases phosphorylation
increases expression
decreases response to substance
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of MDM2 protein]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]
Etoposide results in decreased expression of MDM2 protein
Etoposide results in increased expression of MDM2 mRNA; Etoposide results in increased expression of MDM2 protein
Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]
MDM2 promoter SNP results in decreased susceptibility to Etoposide
CTD PMID:15459018, PMID:16120219, PMID:17575151, PMID:17935137, PMID:18096571, PMID:25078064, PMID:25744307, PMID:26259609, PMID:31542801 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me2 malic enzyme 2 decreases expression ISO Etoposide results in decreased expression of ME2 protein CTD PMID:29733421 NCBI chr18:69,737,515...69,784,099
Ensembl chr18:69,738,686...69,784,099
JBrowse link
G Mir135b microRNA 135b increases expression ISO Etoposide results in increased expression of MIR135B mRNA CTD PMID:27570640 NCBI chr13:48,976,986...48,977,082
Ensembl chr13:48,976,986...48,977,082
JBrowse link
G Mir139 microRNA 139 increases expression ISO Etoposide results in increased expression of MIR139 mRNA CTD PMID:29397400 NCBI chr 1:166,589,545...166,589,612
Ensembl chr 1:166,589,545...166,589,612
JBrowse link
G Mir196b microRNA 196b increases expression ISO Etoposide results in increased expression of MIR196B mRNA CTD PMID:27570640 NCBI chr 4:82,199,056...82,199,140
Ensembl chr 4:82,199,056...82,199,140
JBrowse link
G Mir34c microRNA 34c increases expression ISO Etoposide results in increased expression of MIR34C mRNA CTD PMID:29397400 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mlana melan-A affects response to substance ISO MLANA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:247,869,756...247,883,558
Ensembl chr 1:247,869,756...247,884,442
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor affects response to substance ISO MLLT11 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression
multiple interactions
ISO Etoposide results in decreased expression of MMP1 protein
pifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein]
CTD PMID:18557930 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mocos molybdenum cofactor sulfurase affects response to substance ISO MOCOS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Mpo myeloperoxidase increases metabolic processing ISO MPO protein results in increased metabolism of Etoposide CTD PMID:16841962 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Etoposide results in decreased expression of MPZL1 mRNA CTD PMID:24211769 NCBI chr13:83,805,244...83,842,074
Ensembl chr13:83,805,244...83,842,051
JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression
affects expression
ISO Etoposide results in increased expression of MR1 mRNA
Etoposide affects the expression of MR1 mRNA
CTD PMID:21527772, PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Mras muscle RAS oncogene homolog decreases expression ISO Etoposide results in decreased expression of MRAS mRNA CTD PMID:25270620 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression ISO Etoposide results in decreased expression of MRC1 mRNA CTD PMID:25270620 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 decreases expression ISO Etoposide results in decreased expression of MRM2 mRNA CTD PMID:24211769 NCBI chr12:16,398,749...16,403,656
Ensembl chr12:16,398,749...16,403,656
JBrowse link
G Msc musculin decreases expression ISO Etoposide results in decreased expression of MSC mRNA CTD PMID:25270620 NCBI chr 5:3,954,902...3,956,974
Ensembl chr 5:3,955,227...3,956,572
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO Etoposide results in decreased expression of MSH6 mRNA CTD PMID:24211769 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 increases expression ISO Etoposide results in increased expression of ND4 mRNA CTD PMID:26259609 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Etoposide results in decreased expression of MTHFD2 mRNA CTD PMID:25270620 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of MTOR protein CTD PMID:27769712 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 affects response to substance ISO MTUS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:54,240,892...54,386,131
Ensembl chr16:54,291,251...54,386,129
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein affects response to substance ISO MXI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases response to substance
multiple interactions
ISO Etoposide results in decreased expression of MYC; Etoposide results in decreased expression of MYC mRNA
MYC protein results in increased susceptibility to Etoposide
MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
CTD PMID:9454737, PMID:21324178, PMID:21527772 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance
ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide
MYCN protein results in decreased susceptibility to Etoposide
CTD PMID:10348353 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO Etoposide results in decreased expression of MYH7 mRNA CTD PMID:29397400 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myl2 myosin light chain 2 decreases expression ISO Etoposide results in decreased expression of MYL2 mRNA CTD PMID:29397400 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myl3 myosin light chain 3 decreases expression ISO Etoposide results in decreased expression of MYL3 mRNA CTD PMID:29397400 NCBI chr 8:119,030,852...119,036,996
Ensembl chr 8:119,030,875...119,036,996
JBrowse link
G Myom2 myomesin 2 decreases expression ISO Etoposide results in decreased expression of MYOM2 mRNA CTD PMID:29397400 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Myot myotilin increases expression ISO Etoposide results in increased expression of MYOT mRNA CTD PMID:29397400 NCBI chr18:35,573,978...35,593,541
Ensembl chr18:35,574,002...35,593,541
JBrowse link
G Myt1 myelin transcription factor 1 decreases expression ISO Etoposide results in decreased expression of MYT1 mRNA CTD PMID:16120219 NCBI chr 3:177,281,365...177,341,550
Ensembl chr 3:177,310,753...177,341,547
JBrowse link
G Nabp2 nucleic acid binding protein 2 multiple interactions
increases acetylation
ISO C646 compound inhibits the reaction [Etoposide results in increased acetylation of NABP2 protein] CTD PMID:26170237 NCBI chr 7:2,820,006...2,825,627
Ensembl chr 7:2,820,007...2,825,608
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects response to substance ISO NAP1L1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nck2 NCK adaptor protein 2 decreases expression ISO Etoposide results in decreased expression of NCK2 mRNA CTD PMID:17374387 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Etoposide results in decreased expression of NECTIN2 mRNA CTD PMID:25270620 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 affects response to substance ISO NEDD9 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO Etoposide results in decreased expression of NEK2 mRNA CTD PMID:16120219 NCBI chr13:110,511,546...110,524,750
Ensembl chr13:110,511,668...110,522,769
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases response to substance
multiple interactions
ISO NFE2L2 mRNA results in decreased susceptibility to Etoposide
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]
CTD PMID:26708503, PMID:27982581 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases degradation
ISO wortmannin inhibits the reaction [Etoposide results in increased degradation of NFKBIA protein] CTD PMID:12637521, PMID:17935137 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Niban1 niban apoptosis regulator 1 affects response to substance ISO NIBAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
G Nmt2 N-myristoyltransferase 2 affects response to substance ISO NMT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:78,919,235...78,966,013
Ensembl chr17:78,921,793...78,962,476
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP
ISO
Etoposide results in increased expression of NOS2 mRNA
Etoposide results in increased expression of NOS2 protein
CTD PMID:15135310, PMID:26259609 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npas1 neuronal PAS domain protein 1 increases expression ISO Etoposide results in increased expression of NPAS1 mRNA CTD PMID:21527772 NCBI chr 1:78,420,646...78,441,841
Ensembl chr 1:78,420,652...78,440,738
JBrowse link
G Npnt nephronectin increases expression ISO Etoposide results in increased expression of NPNT mRNA CTD PMID:25270620 NCBI chr 2:238,001,767...238,068,886
Ensembl chr 2:238,002,990...238,068,694
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects response to substance
increases expression
multiple interactions
ISO NQO1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NQO1 mRNA
HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]
CTD PMID:16217747, PMID:20980392, PMID:29397400 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression ISO Etoposide results in decreased expression of NR0B1 mRNA CTD PMID:25270620 NCBI chr  X:54,734,385...54,738,513
Ensembl chr  X:54,734,385...54,738,513
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 affects localization
affects response to substance
multiple interactions
ISO Etoposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Etoposide
Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]
CTD PMID:25914138 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
affects response to substance
increases expression
ISO Etoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Etoposide results in increased expression of and affects the localization of NR1H3 protein; NR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]
NR1H3 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NR1H3 mRNA
CTD PMID:25914138 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
multiple interactions
increases activity
ISO NR1I2 protein affects the susceptibility to Etoposide
[Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:17279585, PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Etoposide inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] CTD PMID:30818834 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrap nebulin-related anchoring protein decreases expression ISO Etoposide results in decreased expression of NRAP mRNA CTD PMID:29397400 NCBI chr 1:277,104,519...277,181,397
Ensembl chr 1:277,104,514...277,181,414
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Etoposide results in increased expression of NRG1 mRNA CTD PMID:29397400 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 affects response to substance
decreases expression
ISO NRIP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NRIP1 mRNA; Etoposide results in decreased expression of NRIP1 protein
CTD PMID:16217747, PMID:25914138 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator affects response to substance
decreases expression
ISO NUPR1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NUPR1 mRNA
CTD PMID:16217747, PMID:25270620 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein affects response to substance ISO OCA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:114,661,970...114,987,433
Ensembl chr 1:114,679,537...114,987,433
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression
multiple interactions
ISO Etoposide results in decreased expression of OGG1 mRNA
wogonin inhibits the reaction [Etoposide results in decreased expression of OGG1 mRNA]
CTD PMID:23872129 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO Etoposide results in increased expression of P2RX7 mRNA CTD PMID:25270620 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 decreases expression ISO Etoposide results in decreased expression of PABPC1 protein CTD PMID:29733421 NCBI chr 7:75,409,581...75,421,874
Ensembl chr 7:75,409,581...75,422,268
JBrowse link
G Palb2 partner and localizer of BRCA2 decreases expression ISO Etoposide results in decreased expression of PALB2 mRNA CTD PMID:24211769 NCBI chr 1:192,064,586...192,088,547
Ensembl chr 1:192,064,589...192,088,520
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression ISO Etoposide results in increased expression of PAPSS2 mRNA CTD PMID:25270620 NCBI chr 1:251,145,264...251,230,716
Ensembl chr 1:251,145,253...251,230,715
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases degradation
EXP
ISO
Etoposide results in increased cleavage of PARP1 protein
3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]; Nicotine inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]
Niacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
CTD PMID:8840993, PMID:9454737, PMID:12690110, PMID:16014620, PMID:16545138, PMID:16799960, PMID:16807353, PMID:16844113, PMID:17516866, PMID:17935137, PMID:20457658, PMID:21801448, PMID:25447644, PMID:26259609, PMID:30890322 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pbk PDZ binding kinase affects response to substance ISO PBK protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr 7:144,077,901...144,103,723
Ensembl chr 7:144,078,496...144,101,893
JBrowse link
G Pcbp4 poly(rC) binding protein 4 decreases expression ISO Etoposide results in decreased expression of PCBP4 mRNA CTD PMID:25270620 NCBI chr 8:115,154,848...115,165,706
Ensembl chr 8:115,155,470...115,165,706
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression ISO Etoposide results in decreased expression of PCK2 mRNA CTD PMID:25270620 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pde2a phosphodiesterase 2A decreases expression ISO Etoposide results in decreased expression of PDE2A mRNA CTD PMID:25270620 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158
JBrowse link
G Pde4b phosphodiesterase 4B affects response to substance ISO PDE4B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdgfc platelet derived growth factor C affects response to substance ISO PDGFC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:179,952,227...180,126,897
Ensembl chr 2:179,952,227...180,128,283
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO Etoposide results in decreased expression of PDK1 mRNA CTD PMID:29397400 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Etoposide results in increased expression of PDK4 mRNA CTD PMID:29397400 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdlim3 PDZ and LIM domain 3 increases expression ISO Etoposide results in increased expression of PDLIM3 mRNA CTD PMID:29397400 NCBI chr16:49,543,140...49,574,362
Ensembl chr16:49,543,142...49,574,390
JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor decreases expression ISO Etoposide results in decreased expression of PELO mRNA CTD PMID:24211769 NCBI chr 2:47,266,758...47,268,526
Ensembl chr 2:47,266,738...47,268,625
JBrowse link
G Perp p53 apoptosis effector related to PMP22 increases expression ISO Etoposide results in increased expression of PERP mRNA CTD PMID:21382384, PMID:25270620 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846
JBrowse link
G Phgdh phosphoglycerate dehydrogenase affects response to substance ISO PHGDH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO Etoposide results in increased expression of PHLDA3 mRNA CTD PMID:25270620 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A multiple interactions ISO [Cisplatin co-treated with Etoposide] results in increased mutagenesis of PIGA CTD PMID:21826740 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta affects response to substance ISO PIP5K1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:242,168,462...242,441,247
Ensembl chr 1:242,168,462...242,441,247
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Etoposide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO Etoposide results in decreased expression of PLK1 mRNA CTD PMID:25270620 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO Etoposide results in increased expression of PLK2 mRNA CTD PMID:21527772 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Etoposide results in increased expression of PLK3 mRNA CTD PMID:17374387 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Plp1 proteolipid protein 1 affects response to substance ISO PLP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348
JBrowse link
G Plpp2 phospholipid phosphatase 2 decreases expression ISO Etoposide results in decreased expression of PLPP2 mRNA CTD PMID:25270620 NCBI chr 7:13,062,168...13,070,281
Ensembl chr 7:13,062,196...13,070,280
JBrowse link
G Pm20d1 peptidase M20 domain containing 1 increases expression ISO Etoposide results in increased expression of PM20D1 mRNA CTD PMID:25270620 NCBI chr13:48,575,094...48,596,515
Ensembl chr13:48,575,091...48,596,515
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Etoposide results in increased expression of PMAIP1 mRNA CTD PMID:21801448 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pmel premelanosome protein affects response to substance ISO PMEL protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:3,133,347...3,143,827
Ensembl chr 7:3,133,506...3,143,911
JBrowse link
G Pmp2 peripheral myelin protein 2 affects response to substance ISO PMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:93,827,504...93,831,419
Ensembl chr 2:93,827,504...93,831,419