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G |
CYP2C18 |
cytochrome P450 2C21 |
increases hydroxylation |
EXP |
CYP2C19 protein results in increased hydroxylation of Diclofenac |
CTD |
PMID:15677349 |
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NCBI chr28:8,727,010...8,750,427
Ensembl chr28:8,727,019...8,750,587
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G |
CYP2C41 |
cytochrome P450 2C41 |
affects metabolic processing |
EXP |
CYP2C9 protein affects the metabolism of Diclofenac |
CTD |
PMID:15801540 |
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
decreases activity |
EXP |
Diclofenac results in decreased activity of PTGS1 protein alternative form |
CTD |
PMID:12242329 |
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NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819
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G |
CPNE6 |
copine 6 |
decreases activity |
EXP |
Flufenamic Acid results in decreased activity of DHRS4 protein |
CTD |
PMID:17827741 |
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NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744
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G |
CDIPT |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
multiple interactions affects activity |
EXP |
[Hexachlorocyclohexane affects the activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate |
CTD |
PMID:2579070 |
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NCBI chr 6:17,910,141...17,914,573
Ensembl chr 6:17,910,192...17,914,653
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G |
SLC47A1 |
solute carrier family 47 member 1 |
decreases activity |
EXP |
hexaconazole results in decreased activity of SLC47A1 protein |
CTD |
PMID:36669674 |
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NCBI chr 5:40,643,420...40,679,130
Ensembl chr 5:40,642,784...40,679,946
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G |
SLC47A2 |
solute carrier family 47 member 2 |
decreases activity |
EXP |
hexaconazole results in decreased activity of SLC47A2 protein |
CTD |
PMID:36669674 |
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NCBI chr 5:40,491,306...40,515,430
Ensembl chr 5:40,491,933...40,540,136
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G |
AHR |
aryl hydrocarbon receptor |
multiple interactions |
EXP |
[iprodione binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein |
CTD |
PMID:24389113 |
|
NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions |
EXP |
[iprodione binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein |
CTD |
PMID:24389113 |
|
NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
affects metabolic processing |
EXP |
CYP2E1 protein affects the metabolism of 2-cresol |
CTD |
PMID:8592870 |
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NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754
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G |
CYP2C41 |
cytochrome P450 2C41 |
affects metabolic processing |
EXP |
CYP2C11 protein affects the metabolism of 4-cresol |
CTD |
PMID:8592870 |
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
affects metabolic processing |
EXP |
CYP2E1 protein affects the metabolism of 4-cresol |
CTD |
PMID:8592870 |
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NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754
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G |
SLC22A2 |
solute carrier family 22 member 2 |
decreases activity |
EXP |
penconazole results in decreased activity of SLC22A2 protein |
CTD |
PMID:36669674 |
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NCBI chr 1:49,327,621...49,348,435
Ensembl chr 1:49,327,296...49,348,435
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G |
SLC22A5 |
solute carrier family 22 member 5 |
decreases activity |
EXP |
penconazole results in decreased activity of SLC22A5 protein |
CTD |
PMID:36669674 |
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NCBI chr11:20,659,023...20,686,359
Ensembl chr11:20,598,888...20,683,087
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G |
SLC47A1 |
solute carrier family 47 member 1 |
decreases activity |
EXP |
penconazole results in decreased activity of SLC47A1 protein |
CTD |
PMID:36669674 |
|
NCBI chr 5:40,643,420...40,679,130
Ensembl chr 5:40,642,784...40,679,946
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G |
SLC47A2 |
solute carrier family 47 member 2 |
decreases activity |
EXP |
penconazole results in decreased activity of SLC47A2 protein |
CTD |
PMID:36669674 |
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NCBI chr 5:40,491,306...40,515,430
Ensembl chr 5:40,491,933...40,540,136
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G |
AHR |
aryl hydrocarbon receptor |
multiple interactions |
EXP |
[2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to prochloraz; [prochloraz binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein; [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to prochloraz |
CTD |
PMID:24389113 |
|
NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions |
EXP |
[prochloraz binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein |
CTD |
PMID:24389113 |
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NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
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G |
ACHE |
acetylcholinesterase |
multiple interactions decreases activity |
EXP |
[Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein] |
CTD |
PMID:16915560 |
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NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Soman results in decreased activity of BCHE protein |
CTD |
PMID:16915560 |
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NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583
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G |
SLC22A2 |
solute carrier family 22 member 2 |
decreases activity |
EXP |
tebuconazole results in decreased activity of SLC22A2 protein |
CTD |
PMID:36669674 |
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NCBI chr 1:49,327,621...49,348,435
Ensembl chr 1:49,327,296...49,348,435
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G |
SLC22A5 |
solute carrier family 22 member 5 |
decreases activity |
EXP |
tebuconazole results in decreased activity of SLC22A5 protein |
CTD |
PMID:36669674 |
|
NCBI chr11:20,659,023...20,686,359
Ensembl chr11:20,598,888...20,683,087
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G |
SLC47A1 |
solute carrier family 47 member 1 |
decreases activity |
EXP |
tebuconazole results in decreased activity of SLC47A1 protein |
CTD |
PMID:36669674 |
|
NCBI chr 5:40,643,420...40,679,130
Ensembl chr 5:40,642,784...40,679,946
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G |
SLC47A2 |
solute carrier family 47 member 2 |
decreases activity |
EXP |
tebuconazole results in decreased activity of SLC47A2 protein |
CTD |
PMID:36669674 |
|
NCBI chr 5:40,491,306...40,515,430
Ensembl chr 5:40,491,933...40,540,136
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G |
SLC22A5 |
solute carrier family 22 member 5 |
decreases activity |
EXP |
triticonazole results in decreased activity of SLC22A5 protein |
CTD |
PMID:36669674 |
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NCBI chr11:20,659,023...20,686,359
Ensembl chr11:20,598,888...20,683,087
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G |
SLC47A1 |
solute carrier family 47 member 1 |
decreases activity |
EXP |
triticonazole results in decreased activity of SLC47A1 protein |
CTD |
PMID:36669674 |
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NCBI chr 5:40,643,420...40,679,130
Ensembl chr 5:40,642,784...40,679,946
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G |
SLC22A5 |
solute carrier family 22 member 5 |
decreases activity |
EXP |
uniconazole results in decreased activity of SLC22A5 protein |
CTD |
PMID:36669674 |
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NCBI chr11:20,659,023...20,686,359
Ensembl chr11:20,598,888...20,683,087
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G |
SLC47A1 |
solute carrier family 47 member 1 |
decreases activity |
EXP |
uniconazole results in decreased activity of SLC47A1 protein |
CTD |
PMID:36669674 |
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NCBI chr 5:40,643,420...40,679,130
Ensembl chr 5:40,642,784...40,679,946
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