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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetophenazine
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Accession:CHEBI:2401 term browser browse the term
Definition:A member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the nitogen atom and an acetyl group at position 2.
Synonyms:exact_synonym: 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone
 related_synonym: Formula=C23H29N3O2S;   InChI=1S/C23H29N3O2S/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27/h2-3,5-8,17,27H,4,9-16H2,1H3;   InChIKey=WNTYBHLDCKXEOT-UHFFFAOYSA-N;   SMILES=CC(=O)c1ccc2Sc3ccccc3N(CCCN3CCN(CCO)CC3)c2c1
 xref: Beilstein:57631;   CAS:2751-68-0;   DrugBank:DB01063;   Drug_Central:59;   HMDB:HMDB0015196;   KEGG:C06807
 xref_mesh: MESH:C100162
 xref: PMID:13904111;   PMID:13986480;   PMID:14020672;   PMID:14211419;   Reaxys:57631;   Wikipedia:Acetophenazine



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acetophenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO acetophenazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        inhibitor 18575
          ferroptosis inhibitor 7524
            10H-phenothiazine 31
              acetophenazine 1
                acetophenazine dimaleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    main group molecular entity 19698
                      s-block molecular entity 19479
                        hydrogen molecular entity 19471
                          hydrides 18834
                            inorganic hydride 17691
                              pnictogen hydride 17671
                                nitrogen hydride 17543
                                  azane 17278
                                    ammonia 17277
                                      organic amino compound 17277
                                        tertiary amino compound 8697
                                          N-alkylpiperazine 3131
                                            N-(2-hydroxyethyl)piperazine 87
                                              acetophenazine 1
                                                acetophenazine dimaleate 0
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