Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetochlor
go back to main search page
Accession:CHEBI:2394 term browser browse the term
Definition:A monocarboxylic acid amide that is N-phenylacetamide carrying an ethyl and a methyl group at positions 2 and 6 respectively on the benzene ring while one of the methyl hydrogens as well as the hydrogen attached to the nitrogen atom have been replaced by a chloro and an ethoxymethyl group respectively.
Synonyms:exact_synonym: 2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide
 related_synonym: 2-Chloro-2'-methyl-6-ethyl-N-ethoxymethylacetanilide;   2-Chloro-N-(ethoxymethyl)-6'-ethyl-o-acetotoluidide;   2-Chloro-N-(ethoxymethyl)-6'-ethylacet-o-toluidide;   Acetochlore;   Formula=C14H20ClNO2;   InChI=1S/C14H20ClNO2/c1-4-12-8-6-7-11(3)14(12)16(10-18-5-2)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3;   InChIKey=VTNQPKFIQCLBDU-UHFFFAOYSA-N;   SMILES=CCOCN(C(=O)CCl)c1c(C)cccc1CC
 xref: Beilstein:2859702;   CAS:34256-82-1;   KEGG:C10925
 xref_mesh: MESH:C043377
 xref: PMID:16646021;   PMID:17534384;   PPDB:12;   Pesticides:acetochlor;   Reaxys:2859702;   Wikipedia:Acetochlor


show annotations for term's descendants           Sort by:
 
acetochlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity
multiple interactions
ISO acetochlor results in increased activity of ABCB1 protein
ABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]
CTD PMID:18433974 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases export ISO ABCC1 protein results in increased export of acetochlor metabolite CTD PMID:18433974 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Aplf aprataxin and PNKP like factor affects response to substance ISO APLF gene SNP affects the susceptibility to acetochlor CTD PMID:25622337 NCBI chr 4:119,514,822...119,568,764
Ensembl chr 4:119,514,840...119,568,736
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO acetochlor results in increased expression of BAD protein CTD PMID:25291404 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO acetochlor results in increased expression of BAK1 protein CTD PMID:25291404 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO acetochlor results in increased expression of BAX protein CTD PMID:25291404 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2l1 Bcl2-like 1 affects expression ISO acetochlor affects the expression of BCL2L1 protein CTD PMID:25291404 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO acetochlor results in increased expression of BID protein CTD PMID:25291404 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased expression of CASP3 protein modified form] CTD PMID:25291404 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of CASP9 protein] CTD PMID:25291404 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of acetochlor CTD PMID:11133395 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of acetochlor CTD PMID:11133395 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Gfral GDNF family receptor alpha like affects response to substance ISO GFRAL gene SNP affects the susceptibility to acetochlor CTD PMID:25622337 NCBI chr 8:83,235,647...83,282,635
Ensembl chr 8:83,236,103...83,280,888
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased phosphorylation of MAPK1 protein] CTD PMID:25291404 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO acetochlor results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased phosphorylation of MAPK3 protein]
CTD PMID:25291404 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO acetochlor affects the expression of MCL1 protein CTD PMID:25291404 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of PARP1 protein] CTD PMID:25291404 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rimklb ribosomal modification protein rimK-like family member B affects response to substance ISO RIMKLB gene SNP affects the susceptibility to acetochlor CTD PMID:25622337 NCBI chr 4:155,258,241...155,292,809
Ensembl chr 4:155,260,103...155,275,161
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO acetochlor binds to THRB protein CTD PMID:28973306 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        xenobiotic 18393
          acetochlor 19
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19429
                        hydrogen molecular entity 19423
                          hydrides 18758
                            inorganic hydride 17453
                              pnictogen hydride 17428
                                nitrogen hydride 17272
                                  azane 17003
                                    ammonia 17002
                                      organic amino compound 17001
                                        amine 7796
                                          primary amine 5696
                                            primary arylamine 2970
                                              aniline 2810
                                                anilide 267
                                                  N-phenylacetamide 222
                                                    acetochlor 19
paths to the root