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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:divalent carboacyl group
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Accession:CHEBI:23855 term browser browse the term
Definition:A divalent carboacyl group is a group formed by loss of OH from two carboxy groups of a polycarboxylic acid.
Synonyms:related_synonym: divalent acyl group;   divalent carboacyl groups;   divalent carboxylic acyl groups



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Arecaidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO arecaidine results in increased expression of TIMP1 mRNA; arecaidine results in increased expression of TIMP1 protein CTD PMID:16311067 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
Cassine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 multiple interactions ISO [cassine co-treated with spectaline] results in decreased expression of CCND1 mRNA CTD PMID:26616281 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [cassine co-treated with spectaline] results in decreased phosphorylation of MAPK1 protein CTD PMID:26616281 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [cassine co-treated with spectaline] results in decreased phosphorylation of MAPK3 protein CTD PMID:26616281 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
N'-Nitrosoanabasine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein affects the metabolism of and results in increased activity of N'-nitrosoanabasine CTD PMID:11774366 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO N'-nitrosoanabasine inhibits the reaction [[CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone]
N'-nitrosoanabasine results in decreased activity of CYP2A13 protein
CTD PMID:27567546 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein affects the metabolism of and results in increased activity of N'-nitrosoanabasine CTD PMID:11774366 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of N'-nitrosoanabasine CTD PMID:18238858 NCBI chr 9:88,762,250...88,808,465 JBrowse link
N-Nitrosoguvacoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases activity ISO CYP2A13 protein results in increased activity of N-nitrosoguvacoline CTD PMID:15725615 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
Nicotine imine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases chemical synthesis ISO CYP2B6 protein results in increased chemical synthesis of nicotine imine CTD PMID:30906561 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
Pancratistatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO pancratistatin results in increased activity of CASP3 protein CTD PMID:15726366 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      group 19734
        organic group 18730
          acyl group 17487
            carboacyl group 17487
              divalent carboacyl group 10
                N-acetyl group 0
                aspartoyl group + 0
                butenedioyl group + 0
                citraconoyl group + 10
                cystyl group + 0
                glutamoyl group + 0
                hexanedioyl group 0
                malonyl group 0
                maloyl group 0
                phthaloyl group 0
                succinyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      carbon group element atom 19631
                        carbon atom 19621
                          organic molecular entity 19621
                            organic group 18730
                              organic divalent group 18721
                                organodiyl group 18721
                                  carbonyl group 18670
                                    carbonyl compound 18670
                                      carboxylic acid 18367
                                        carboacyl group 17487
                                          divalent carboacyl group 10
                                            N-acetyl group 0
                                            aspartoyl group + 0
                                            butenedioyl group + 0
                                            citraconoyl group + 10
                                            cystyl group + 0
                                            glutamoyl group + 0
                                            hexanedioyl group 0
                                            malonyl group 0
                                            maloyl group 0
                                            phthaloyl group 0
                                            succinyl group 0
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