Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:deoxyhexose
go back to main search page
Accession:CHEBI:23628 term browser browse the term
Definition:Any C6 deoxy sugar having at least one hydroxy group replaced by hydrogen.
Synonyms:related_synonym: deoxyhexoses

show annotations for term's descendants           Sort by:
 
2-deoxy-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases uptake
multiple interactions		 ISO A2M protein modified form results in increased uptake of Deoxyglucose
HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose]		 CTD PMID:25720493 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
Ensembl chr 4:154,309,426...154,359,137 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon] CTD PMID:16221533 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO [Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] CTD PMID:28842488 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424 		JBrowse link
G Abra actin-binding Rho activating protein multiple interactions
increases uptake		 EXP CCG 1423 promotes the reaction [ABRA mutant form promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]; CCG 1423 promotes the reaction [INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]]; INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose] CTD PMID:21393865 NCBI chr 7:80,792,615...80,796,683
Ensembl chr 7:80,792,600...80,796,670 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases uptake
multiple interactions		 ISO ADIPOQ protein modified form results in increased uptake of Deoxyglucose
Indinavir inhibits the reaction [ADIPOQ protein modified form results in increased uptake of Deoxyglucose]		 CTD PMID:29991592 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Agrp agouti related neuropeptide increases expression EXP Deoxyglucose results in increased expression of AGRP mRNA CTD PMID:10683841 NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP protein CTD PMID:17405930 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Atg3 autophagy related 3 multiple interactions ISO Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of ATG3 mRNA] CTD PMID:26079942 NCBI chr11:60,585,192...60,613,706
Ensembl chr11:60,585,171...60,613,718 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase multiple interactions ISO [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of ATG4B mRNA CTD PMID:26079942 NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637 		JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] CTD PMID:20593179 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression		 ISO Deoxyglucose promotes the reaction [arsenic trioxide results in increased localization of and results in increased activity of BAX protein]; Deoxyglucose results in increased localization of and results in increased activity of BAX protein
Deoxyglucose results in decreased expression of BAX mRNA		 CTD PMID:23041229 PMID:26079942 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of BCL2 mRNA] CTD PMID:26079942 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases response to substance ISO BCL2L1 protein results in decreased susceptibility to Deoxyglucose CTD PMID:10679475 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in decreased expression of BECN1 protein; [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of BECN1 mRNA CTD PMID:26079942 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]; Deoxyglucose results in increased cleavage of and results in increased activity of BID protein CTD PMID:23041229 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage		 ISO
EXP		 ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP3 protein
Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]]
Deoxyglucose results in increased activity of CASP3 protein
Corticosterone inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]; GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]		 CTD PMID:10506188 PMID:15755911 PMID:20593179 PMID:23041229 PMID:29095437 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Deoxyglucose co-treated with Cisplatin] results in increased activity of CASP9 protein; Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:20138251 PMID:23041229 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of CDKN1A mRNA CTD PMID:26079942 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 affects response to substance ISO CHRM3 protein affects the susceptibility to Deoxyglucose CTD PMID:14724830 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex affects localization ISO Deoxyglucose analog affects the localization of CHUK protein CTD PMID:27931795 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169 		JBrowse link
G Ctsd cathepsin D increases expression EXP Deoxyglucose results in increased expression of CTSD protein CTD PMID:20026095 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451 		JBrowse link
G Cul7 cullin 7 multiple interactions ISO [INS1 protein co-treated with CUL7 mutant form] results in increased uptake of Deoxyglucose CTD PMID:24219910 NCBI chr 9:16,629,491...16,643,527
Ensembl chr 9:16,629,401...16,643,182 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein] CTD PMID:20593179 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases import		 ISO AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose]
EGFR protein mutant form results in increased import of Deoxyglucose		 CTD PMID:19625624 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Deoxyglucose results in decreased phosphorylation of and results in increased expression of EIF4EBP1 protein CTD PMID:23363784 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO [Deoxyglucose co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein; Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728 		JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions
increases transport		 ISO Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose] CTD PMID:11533133 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955 		JBrowse link
G Galr1 galanin receptor 1 increases expression EXP Deoxyglucose results in increased expression of GALR1 mRNA CTD PMID:9858361 PMID:9928191 NCBI chr18:79,243,009...79,258,570
Ensembl chr18:79,243,009...79,258,570 		JBrowse link
G Gcg glucagon multiple interactions
increases secretion		 ISO Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] CTD PMID:1378463 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein] CTD PMID:10506188 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Deoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO Deoxyglucose results in decreased expression of H2AX protein CTD PMID:23363784 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Deoxyglucose results in decreased expression of and results in decreased activity of HK2 protein CTD PMID:32619556 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Deoxyglucose inhibits the reaction [arsenic trioxide results in increased expression of HMOX1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein] CTD PMID:25246272 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression
multiple interactions		 ISO Deoxyglucose results in increased expression of HSP90B1 protein
4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSP90B1 protein]		 CTD PMID:31022492 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 ISO 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 mRNA]; 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]
Deoxyglucose results in increased expression of HSPA5 mRNA; Deoxyglucose results in increased expression of HSPA5 protein		 CTD PMID:20593179 PMID:25720493 PMID:31022492 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Htra2 HtrA serine peptidase 2 multiple interactions
decreases localization		 ISO Deoxyglucose promotes the reaction [arsenic trioxide results in decreased localization of HTRA2 protein]
Deoxyglucose results in decreased localization of HTRA2 protein		 CTD PMID:23041229 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Deoxyglucose results in increased phosphorylation of and results in increased activity of IGF1R protein CTD PMID:23041229 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516 		JBrowse link
G Il1b interleukin 1 beta decreases response to substance
multiple interactions		 ISO Deoxyglucose results in decreased susceptibility to IL1B protein
Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]		 CTD PMID:21211511 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Ins2 insulin 2 increases uptake
multiple interactions		 ISO INS protein results in increased uptake of Deoxyglucose; INS results in increased uptake of Deoxyglucose
METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitates inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]		 CTD PMID:2173694 PMID:16483873 PMID:20165829 PMID:21324916 PMID:25720493 PMID:25815690 PMID:30213948 PMID:31877369 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Deoxyglucose analog results in decreased expression of ITGB1 protein CTD PMID:27931795 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO [Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein; Deoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]; Pyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]
Deoxyglucose results in decreased activity of KCNH2 protein		 CTD PMID:12531891 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] CTD PMID:28842488 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127 		JBrowse link
G Lep leptin multiple interactions
decreases secretion		 EXP [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein
Deoxyglucose results in decreased secretion of LEP protein		 CTD PMID:10780946 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of MAP1LC3A mRNA] CTD PMID:26079942 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases prenylation		 ISO ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Mannose inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] CTD PMID:20593179 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO arsenic trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23041229 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO		 MAPK3 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose]
Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:11978788 PMID:23041229 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose] CTD PMID:30213948 NCBI chr10:110,893,261...110,907,256
Ensembl chr10:110,893,232...110,907,243 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression		 ISO Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein]
Deoxyglucose analog results in decreased expression of MMP13 protein		 CTD PMID:21211511 PMID:27931795 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Deoxyglucose analog results in decreased expression of MMP9 protein CTD PMID:27931795 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Deoxyglucose results in decreased phosphorylation of and results in increased expression of MTOR protein; Deoxyglucose results in increased phosphorylation of and results in increased activity of MTOR protein CTD PMID:23041229 PMID:23363784 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases expression		 ISO [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] affects the expression of NFKB1 mRNA
Deoxyglucose results in decreased expression of NFKB1 mRNA		 CTD PMID:26079942 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Deoxyglucose promotes the reaction [STO 609 inhibits the reaction [Histamine results in increased phosphorylation of NOS2 protein]] CTD PMID:21145922 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Npy neuropeptide Y increases expression EXP Deoxyglucose results in increased expression of NPY mRNA CTD PMID:10683841 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Deoxyglucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO Deoxyglucose inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]
Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]]
Deoxyglucose results in increased cleavage of PARP1 protein		 CTD PMID:25246272 PMID:29095437 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pmch pro-melanin-concentrating hormone increases expression EXP Deoxyglucose results in increased expression of PMCH mRNA CTD PMID:10683841 NCBI chr 7:28,655,206...28,656,522
Ensembl chr 7:28,654,733...28,657,522 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]] CTD PMID:21324916 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects uptake
increases uptake		 ISO PPARG protein affects the uptake of Deoxyglucose
PPARG gene polymorphism results in increased uptake of Deoxyglucose		 CTD PMID:18083318 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha decreases response to substance ISO PPP3CA protein results in decreased susceptibility to Deoxyglucose CTD PMID:10679475 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions EXP RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] CTD PMID:11978788 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Deoxyglucose results in decreased phosphorylation of RPS6 protein CTD PMID:23363784 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
Ensembl chr 5:105,197,857...105,200,148 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions		 ISO Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein
Deoxyglucose results in increased phosphorylation of and results in increased activity of RPS6KB1 protein; oxophenylarsine inhibits the reaction [Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein]		 CTD PMID:16183647 PMID:23041229 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364 		JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Deoxyglucose analog results in increased expression of SERPINB5 protein CTD PMID:27931795 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases uptake		 ISO [arsenite affects the localization of SLC2A1 protein] which results in increased uptake of Deoxyglucose
SLC2A1 protein results in increased uptake of Deoxyglucose
SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]		 CTD PMID:2173694 PMID:14511371 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions
increases transport		 ISO Cytochalasin B inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Fructose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose] CTD PMID:8457197 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases transport
multiple interactions		 ISO SLC2A3 protein results in increased transport of Deoxyglucose
Cytochalasin B inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Galactose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]		 CTD PMID:8457197 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
Ensembl chr 4:155,408,233...155,631,856 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions
increases uptake		 ISO
EXP		 2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]]; [arsenite affects the localization of SLC2A4 protein] which results in increased uptake of Deoxyglucose; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]; Plant Extracts promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]
[Indinavir results in decreased activity of SLC2A4 protein] inhibits the reaction [resveratrol results in increased uptake of Deoxyglucose]; SLC2A4 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; SLC2A4 protein promotes the reaction [resveratrol results in increased uptake of Deoxyglucose]		 CTD PMID:14511371 PMID:18601907 PMID:19477051 PMID:20206685 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487 		JBrowse link
G Slc2a8 solute carrier family 2 member 8 increases uptake EXP
ISO		 SLC2A8 protein results in increased uptake of Deoxyglucose CTD PMID:23396969 NCBI chr 3:12,020,227...12,029,920
Ensembl chr 3:12,020,229...12,029,877 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 protein] CTD PMID:10328827 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein; [bafilomycin A co-treated with Deoxyglucose] affects the expression of SQSTM1 protein; Deoxyglucose inhibits the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA]; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] CTD PMID:26079942 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Deoxyglucose results in increased expression of SREBF1 mRNA CTD PMID:10913129 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009 		JBrowse link
G Stk11 serine/threonine kinase 11 decreases phosphorylation ISO Deoxyglucose results in decreased phosphorylation of STK11 protein CTD PMID:23041229 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
decreases response to substance		 ISO
EXP		 Deoxyglucose results in decreased expression of TNF protein
Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]
Deoxyglucose results in decreased susceptibility to TNF protein
Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]		 CTD PMID:16483873 PMID:21211511 PMID:21778228 PMID:22713545 PMID:23439570 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA]; TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] CTD PMID:21042727 PMID:26079942 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO [arsenic trioxide co-treated with Deoxyglucose] results in decreased expression of XIAP protein CTD PMID:23041229 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000 		JBrowse link
3-deoxyglucosone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 3-deoxyglucosone CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657 		JBrowse link
fucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fut8 fucosyltransferase 8 multiple interactions ISO Fucose analog inhibits the reaction [Mersalyl results in decreased activity of FUT8 protein]; Fucose analog inhibits the reaction [p-Chloromercuribenzoic Acid results in decreased activity of FUT8 protein]; Fucose analog inhibits the reaction [Phenylglyoxal results in decreased activity of FUT8 protein]; Fucose analog inhibits the reaction [Pyridoxal Phosphate results in decreased activity of FUT8 protein] CTD PMID:12770769 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224 		JBrowse link
G Lct lactase increases hydrolysis EXP LCT protein results in increased hydrolysis of Fucose CTD PMID:14701853 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593 		JBrowse link
icariside II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions		 ISO baohuoside I results in decreased phosphorylation of AKT1 protein
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:25119583 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]
baohuoside I results in decreased phosphorylation of AKT1S1 protein		 CTD PMID:25119583 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression EXP baohuoside I results in increased expression of ALPL mRNA CTD PMID:17764702 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO baohuoside I results in increased expression of BAX protein CTD PMID:22687635 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO baohuoside I results in decreased expression of BCL2 protein CTD PMID:22687635 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP baohuoside I results in increased expression of BGLAP mRNA CTD PMID:17764702 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases phosphorylation
multiple interactions		 ISO baohuoside I results in decreased phosphorylation of BRAF protein
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]		 CTD PMID:25119583 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases activity		 ISO baohuoside I results in increased cleavage of CASP3 protein
baohuoside I results in increased activity of CASP3 protein		 CTD PMID:19289254 PMID:22687635 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 increases activity ISO baohuoside I results in increased activity of CASP8 protein CTD PMID:19289254 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage		 ISO baohuoside I results in increased activity of CASP9 protein
baohuoside I results in increased cleavage of CASP9 protein		 CTD PMID:19289254 PMID:22687635 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP baohuoside I results in increased expression of COL1A2 mRNA CTD PMID:17764702 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein] CTD PMID:25119583 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
baohuoside I results in decreased phosphorylation of EGFR protein		 CTD PMID:25119583 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO baohuoside I results in decreased phosphorylation of GSK3B protein CTD PMID:25119583 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]
baohuoside I results in decreased phosphorylation of MAPK1 protein		 CTD PMID:25119583 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
baohuoside I results in decreased phosphorylation of MAPK3 protein		 CTD PMID:25119583 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO baohuoside I results in decreased expression of MKI67 protein CTD PMID:25119583 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein]
baohuoside I results in decreased phosphorylation of MTOR protein		 CTD PMID:25119583 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO baohuoside I results in decreased expression of NOS2 CTD PMID:19289254 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO baohuoside I results in increased cleavage of PARP1 protein
Dinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]		 CTD PMID:19289254 PMID:22687635 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases phosphorylation ISO baohuoside I results in decreased phosphorylation of PDPK1 protein CTD PMID:25119583 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO baohuoside I results in decreased expression of PTGS2
[baohuoside I results in decreased expression of PTGS2] which results in decreased abundance of Dinoprostone; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]		 CTD PMID:19289254 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression EXP baohuoside I results in increased expression of TNFRSF11B mRNA CTD PMID:17764702 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression EXP baohuoside I results in decreased expression of TNFSF11 mRNA CTD PMID:17764702 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO baohuoside I results in decreased expression of VEGFA CTD PMID:19289254 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
phosphoramidon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP phosphoramidon inhibits the reaction [AGT protein results in increased expression of EDNRA protein] CTD PMID:15007106 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:15177934 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Ece1 endothelin converting enzyme 1 multiple interactions EXP EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]]; phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]; phosphoramidon inhibits the reaction [Indomethacin results in increased expression of ECE1 protein] CTD PMID:11145282 PMID:16280098 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Edn1 endothelin 1 decreases expression
multiple interactions		 EXP phosphoramidon results in decreased expression of EDN1 protein
EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]]; EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased expression of EDN1 protein]]; phosphoramidon inhibits the reaction [Indomethacin results in increased expression of EDN1 protein]		 CTD PMID:11145282 PMID:16280098 PMID:16391412 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP phosphoramidon inhibits the reaction [AGT protein results in increased expression of EDNRA protein]; phosphoramidon inhibits the reaction [Phenylephrine results in increased expression of EDNRA protein] CTD PMID:15007106 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP phosphoramidon results in increased expression of EDNRB protein CTD PMID:15007106 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP phosphoramidon inhibits the reaction [Morphine results in decreased expression of ICAM1 protein alternative form] CTD PMID:10070497 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Kel Kell metallo-endopeptidase (Kell blood group) multiple interactions ISO KEL protein alternative form binds to and affects the metabolism of phosphoramidon CTD PMID:15769748 NCBI chr 4:70,979,504...70,996,920
Ensembl chr 4:70,979,504...70,996,395 		JBrowse link
G Lep leptin decreases expression EXP phosphoramidon results in decreased expression of LEP protein CTD PMID:16391412 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:15177934 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:15177934 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mme membrane metallo-endopeptidase multiple interactions EXP phosphoramidon inhibits the reaction [Morphine results in increased activity of MME protein] CTD PMID:10070497 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738 		JBrowse link
G Nts neurotensin multiple interactions ISO phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein]; phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:15177934 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130 		JBrowse link
G Sell selectin L multiple interactions EXP phosphoramidon inhibits the reaction [Morphine results in decreased expression of SELL protein alternative form] CTD PMID:10070497 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP [TAC1 protein co-treated with phosphoramidon] results in increased uptake of Oxygen CTD PMID:9808699 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819 		JBrowse link
rhamnose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oat ornithine aminotransferase multiple interactions EXP Rhamnose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19770
      atom 19768
        nonmetal atom 19651
          oxygen atom 19354
            oxygen molecular entity 19354
              organooxygen compound 18877
                carbohydrates and carbohydrate derivatives 12259
                  carbohydrate 12259
                    deoxy sugar 106
                      deoxyhexose 106
                        2-deoxyhexopyranose 0
                        deoxyallose + 0
                        deoxyaltrose + 0
                        deoxygalactose + 2
                        deoxyglucose + 79
                        deoxygulose + 0
                        deoxyhexose derivative + 16
                        deoxymannose + 26
                        deoxytalose + 0
                        dideoxyhexose + 0
                        tetradeoxyhexose + 0
                        trideoxyhexose + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            heteroorganic entity 19206
                              organochalcogen compound 18951
                                organooxygen compound 18877
                                  carbohydrates and carbohydrate derivatives 12259
                                    carbohydrate 12259
                                      monosaccharide 4187
                                        aldose 2558
                                          aldohexose 2200
                                            deoxyhexose 106
                                              2-deoxyhexopyranose 0
                                              deoxyallose + 0
                                              deoxyaltrose + 0
                                              deoxygalactose + 2
                                              deoxyglucose + 79
                                              deoxygulose + 0
                                              deoxyhexose derivative + 16
                                              deoxymannose + 26
                                              deoxytalose + 0
                                              dideoxyhexose + 0
                                              tetradeoxyhexose + 0
                                              trideoxyhexose + 0
paths to the root