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G |
A2m |
alpha-2-macroglobulin |
increases uptake multiple interactions |
ISO |
A2M protein modified form results in increased uptake of Deoxyglucose HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose] |
CTD |
PMID:25720493 |
|
NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137 Ensembl chr 4:154,309,426...154,359,137
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon] |
CTD |
PMID:16221533 |
|
NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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G |
Abcc9 |
ATP binding cassette subfamily C member 9 |
multiple interactions |
ISO |
[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] |
CTD |
PMID:28842488 |
|
NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
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G |
Abra |
actin-binding Rho activating protein |
multiple interactions increases uptake |
EXP |
CCG 1423 promotes the reaction [ABRA mutant form promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]; CCG 1423 promotes the reaction [INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]]; INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose] |
CTD |
PMID:21393865 |
|
NCBI chr 7:80,792,615...80,796,683
Ensembl chr 7:80,792,600...80,796,670
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases uptake multiple interactions |
ISO |
ADIPOQ protein modified form results in increased uptake of Deoxyglucose Indinavir inhibits the reaction [ADIPOQ protein modified form results in increased uptake of Deoxyglucose] |
CTD |
PMID:29991592 |
|
NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
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G |
Agrp |
agouti related neuropeptide |
increases expression |
EXP |
Deoxyglucose results in increased expression of AGRP mRNA |
CTD |
PMID:10683841 |
|
NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP protein |
CTD |
PMID:17405930 |
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NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Atg3 |
autophagy related 3 |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of ATG3 mRNA] |
CTD |
PMID:26079942 |
|
NCBI chr11:60,585,192...60,613,706
Ensembl chr11:60,585,171...60,613,718
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G |
Atg4b |
autophagy related 4B, cysteine peptidase |
multiple interactions |
ISO |
[demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of ATG4B mRNA |
CTD |
PMID:26079942 |
|
NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] |
CTD |
PMID:20593179 |
|
NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
ISO |
Deoxyglucose promotes the reaction [arsenic trioxide results in increased localization of and results in increased activity of BAX protein]; Deoxyglucose results in increased localization of and results in increased activity of BAX protein Deoxyglucose results in decreased expression of BAX mRNA |
CTD |
PMID:23041229 PMID:26079942 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of BCL2 mRNA] |
CTD |
PMID:26079942 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases response to substance |
ISO |
BCL2L1 protein results in decreased susceptibility to Deoxyglucose |
CTD |
PMID:10679475 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
[bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in decreased expression of BECN1 protein; [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of BECN1 mRNA |
CTD |
PMID:26079942 |
|
NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]; Deoxyglucose results in increased cleavage of and results in increased activity of BID protein |
CTD |
PMID:23041229 |
|
NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases cleavage |
ISO EXP |
ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP3 protein Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]] Deoxyglucose results in increased activity of CASP3 protein Corticosterone inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]; GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein] |
CTD |
PMID:10506188 PMID:15755911 PMID:20593179 PMID:23041229 PMID:29095437 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
[Deoxyglucose co-treated with Cisplatin] results in increased activity of CASP9 protein; Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP9 protein |
CTD |
PMID:20138251 PMID:23041229 |
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NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
[demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of CDKN1A mRNA |
CTD |
PMID:26079942 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
affects response to substance |
ISO |
CHRM3 protein affects the susceptibility to Deoxyglucose |
CTD |
PMID:14724830 |
|
NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
affects localization |
ISO |
Deoxyglucose analog affects the localization of CHUK protein |
CTD |
PMID:27931795 |
|
NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
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G |
Ctsd |
cathepsin D |
increases expression |
EXP |
Deoxyglucose results in increased expression of CTSD protein |
CTD |
PMID:20026095 |
|
NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
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G |
Cul7 |
cullin 7 |
multiple interactions |
ISO |
[INS1 protein co-treated with CUL7 mutant form] results in increased uptake of Deoxyglucose |
CTD |
PMID:24219910 |
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NCBI chr 9:16,629,491...16,643,527
Ensembl chr 9:16,629,401...16,643,182
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
ISO |
ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein] |
CTD |
PMID:20593179 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases import |
ISO |
AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] EGFR protein mutant form results in increased import of Deoxyglucose |
CTD |
PMID:19625624 |
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NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Deoxyglucose results in decreased phosphorylation of and results in increased expression of EIF4EBP1 protein |
CTD |
PMID:23363784 |
|
NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[Deoxyglucose co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein; Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:18655187 |
|
NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
multiple interactions increases transport |
ISO |
Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose] |
CTD |
PMID:11533133 |
|
NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
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G |
Galr1 |
galanin receptor 1 |
increases expression |
EXP |
Deoxyglucose results in increased expression of GALR1 mRNA |
CTD |
PMID:9858361 PMID:9928191 |
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NCBI chr18:79,243,009...79,258,570
Ensembl chr18:79,243,009...79,258,570
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G |
Gcg |
glucagon |
multiple interactions increases secretion |
ISO |
Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] |
CTD |
PMID:1378463 |
|
NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
EXP |
GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein] |
CTD |
PMID:10506188 |
|
NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:25246272 |
|
NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
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G |
H2ax |
H2A.X variant histone |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of H2AX protein |
CTD |
PMID:23363784 |
|
NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
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G |
Hk2 |
hexokinase 2 |
multiple interactions |
ISO |
Deoxyglucose results in decreased expression of and results in decreased activity of HK2 protein |
CTD |
PMID:32619556 |
|
NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [arsenic trioxide results in increased expression of HMOX1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein] |
CTD |
PMID:25246272 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:18655187 |
|
NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775 Ensembl chr 6:135,107,271...135,112,775
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression multiple interactions |
ISO |
Deoxyglucose results in increased expression of HSP90B1 protein 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSP90B1 protein] |
CTD |
PMID:31022492 |
|
NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression |
ISO |
4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 mRNA]; 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein] Deoxyglucose results in increased expression of HSPA5 mRNA; Deoxyglucose results in increased expression of HSPA5 protein |
CTD |
PMID:20593179 PMID:25720493 PMID:31022492 |
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NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
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G |
Htra2 |
HtrA serine peptidase 2 |
multiple interactions decreases localization |
ISO |
Deoxyglucose promotes the reaction [arsenic trioxide results in decreased localization of HTRA2 protein] Deoxyglucose results in decreased localization of HTRA2 protein |
CTD |
PMID:23041229 |
|
NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions |
ISO |
Deoxyglucose results in increased phosphorylation of and results in increased activity of IGF1R protein |
CTD |
PMID:23041229 |
|
NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
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G |
Il1b |
interleukin 1 beta |
decreases response to substance multiple interactions |
ISO |
Deoxyglucose results in decreased susceptibility to IL1B protein Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] |
CTD |
PMID:21211511 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Ins2 |
insulin 2 |
increases uptake multiple interactions |
ISO |
INS protein results in increased uptake of Deoxyglucose; INS results in increased uptake of Deoxyglucose METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitates inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] |
CTD |
PMID:2173694 PMID:16483873 PMID:20165829 PMID:21324916 PMID:25720493 PMID:25815690 PMID:30213948 PMID:31877369 |
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NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
ISO |
Deoxyglucose analog results in decreased expression of ITGB1 protein |
CTD |
PMID:27931795 |
|
NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
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G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions decreases activity |
ISO |
[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein; Deoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]; Pyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein] Deoxyglucose results in decreased activity of KCNH2 protein |
CTD |
PMID:12531891 |
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NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
multiple interactions |
ISO |
[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] |
CTD |
PMID:28842488 |
|
NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
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G |
Lep |
leptin |
multiple interactions decreases secretion |
EXP |
[Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein Deoxyglucose results in decreased secretion of LEP protein |
CTD |
PMID:10780946 |
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NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of MAP1LC3A mRNA] |
CTD |
PMID:26079942 |
|
NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases prenylation |
ISO |
ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Mannose inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] |
CTD |
PMID:20593179 |
|
NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
arsenic trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:23041229 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
EXP ISO |
MAPK3 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:11978788 PMID:23041229 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Metrnl |
meteorin-like, glial cell differentiation regulator |
multiple interactions |
ISO |
METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose] |
CTD |
PMID:30213948 |
|
NCBI chr10:110,893,261...110,907,256
Ensembl chr10:110,893,232...110,907,243
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions decreases expression |
ISO |
Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein] Deoxyglucose analog results in decreased expression of MMP13 protein |
CTD |
PMID:21211511 PMID:27931795 |
|
NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases expression |
ISO |
Deoxyglucose analog results in decreased expression of MMP9 protein |
CTD |
PMID:27931795 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
Deoxyglucose results in decreased phosphorylation of and results in increased expression of MTOR protein; Deoxyglucose results in increased phosphorylation of and results in increased activity of MTOR protein |
CTD |
PMID:23041229 PMID:23363784 |
|
NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases expression |
ISO |
[demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] affects the expression of NFKB1 mRNA Deoxyglucose results in decreased expression of NFKB1 mRNA |
CTD |
PMID:26079942 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
Deoxyglucose promotes the reaction [STO 609 inhibits the reaction [Histamine results in increased phosphorylation of NOS2 protein]] |
CTD |
PMID:21145922 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Npy |
neuropeptide Y |
increases expression |
EXP |
Deoxyglucose results in increased expression of NPY mRNA |
CTD |
PMID:10683841 |
|
NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097 Ensembl chr 4:79,557,854...79,565,097
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Deoxyglucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] |
CTD |
PMID:2827574 |
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NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases cleavage |
ISO |
Deoxyglucose inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]] Deoxyglucose results in increased cleavage of PARP1 protein |
CTD |
PMID:25246272 PMID:29095437 |
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NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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G |
Pmch |
pro-melanin-concentrating hormone |
increases expression |
EXP |
Deoxyglucose results in increased expression of PMCH mRNA |
CTD |
PMID:10683841 |
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NCBI chr 7:28,655,206...28,656,522
Ensembl chr 7:28,654,733...28,657,522
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]] |
CTD |
PMID:21324916 |
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NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects uptake increases uptake |
ISO |
PPARG protein affects the uptake of Deoxyglucose PPARG gene polymorphism results in increased uptake of Deoxyglucose |
CTD |
PMID:18083318 |
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NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
decreases response to substance |
ISO |
PPP3CA protein results in decreased susceptibility to Deoxyglucose |
CTD |
PMID:10679475 |
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NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
EXP |
RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] |
CTD |
PMID:11978788 |
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NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Deoxyglucose results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:23363784 |
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NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148 Ensembl chr 5:105,197,857...105,200,148
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation multiple interactions |
ISO |
Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein Deoxyglucose results in increased phosphorylation of and results in increased activity of RPS6KB1 protein; oxophenylarsine inhibits the reaction [Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:16183647 PMID:23041229 |
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NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
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G |
Serpinb5 |
serpin family B member 5 |
increases expression |
ISO |
Deoxyglucose analog results in increased expression of SERPINB5 protein |
CTD |
PMID:27931795 |
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NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions increases uptake |
ISO |
[arsenite affects the localization of SLC2A1 protein] which results in increased uptake of Deoxyglucose SLC2A1 protein results in increased uptake of Deoxyglucose SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose] |
CTD |
PMID:2173694 PMID:14511371 |
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NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
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G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions increases transport |
ISO |
Cytochalasin B inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Fructose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose] |
CTD |
PMID:8457197 |
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NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
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G |
Slc2a3 |
solute carrier family 2 member 3 |
increases transport multiple interactions |
ISO |
SLC2A3 protein results in increased transport of Deoxyglucose Cytochalasin B inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Galactose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose] |
CTD |
PMID:8457197 |
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NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856 Ensembl chr 4:155,408,233...155,631,856
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions increases uptake |
ISO EXP |
2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]]; [arsenite affects the localization of SLC2A4 protein] which results in increased uptake of Deoxyglucose; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]; Plant Extracts promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose] [Indinavir results in decreased activity of SLC2A4 protein] inhibits the reaction [resveratrol results in increased uptake of Deoxyglucose]; SLC2A4 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; SLC2A4 protein promotes the reaction [resveratrol results in increased uptake of Deoxyglucose] |
CTD |
PMID:14511371 PMID:18601907 PMID:19477051 PMID:20206685 |
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NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
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G |
Slc2a8 |
solute carrier family 2 member 8 |
increases uptake |
EXP ISO |
SLC2A8 protein results in increased uptake of Deoxyglucose |
CTD |
PMID:23396969 |
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NCBI chr 3:12,020,227...12,029,920
Ensembl chr 3:12,020,229...12,029,877
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 protein] |
CTD |
PMID:10328827 |
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NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO |
[bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein; [bafilomycin A co-treated with Deoxyglucose] affects the expression of SQSTM1 protein; Deoxyglucose inhibits the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA]; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] |
CTD |
PMID:26079942 |
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NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
ISO |
Deoxyglucose results in increased expression of SREBF1 mRNA |
CTD |
PMID:10913129 |
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NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
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G |
Stk11 |
serine/threonine kinase 11 |
decreases phosphorylation |
ISO |
Deoxyglucose results in decreased phosphorylation of STK11 protein |
CTD |
PMID:23041229 |
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NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions decreases response to substance |
ISO EXP |
Deoxyglucose results in decreased expression of TNF protein Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose] Deoxyglucose results in decreased susceptibility to TNF protein Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]] |
CTD |
PMID:16483873 PMID:21211511 PMID:21778228 PMID:22713545 PMID:23439570 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
[Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA]; TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] |
CTD |
PMID:21042727 PMID:26079942 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Xiap |
X-linked inhibitor of apoptosis |
multiple interactions |
ISO |
[arsenic trioxide co-treated with Deoxyglucose] results in decreased expression of XIAP protein |
CTD |
PMID:23041229 |
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NCBI chr X:128,409,425...128,455,786
Ensembl chr X:128,409,472...128,453,000
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G |
Akr1b8 |
aldo-keto reductase family 1, member B8 |
multiple interactions |
EXP |
[AKR1B8 protein co-treated with NADP] affects the reduction of 3-deoxyglucosone |
CTD |
PMID:18845131 |
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NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
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G |
Fut8 |
fucosyltransferase 8 |
multiple interactions |
ISO |
Fucose analog inhibits the reaction [Mersalyl results in decreased activity of FUT8 protein]; Fucose analog inhibits the reaction [p-Chloromercuribenzoic Acid results in decreased activity of FUT8 protein]; Fucose analog inhibits the reaction [Phenylglyoxal results in decreased activity of FUT8 protein]; Fucose analog inhibits the reaction [Pyridoxal Phosphate results in decreased activity of FUT8 protein] |
CTD |
PMID:12770769 |
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NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
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G |
Lct |
lactase |
increases hydrolysis |
EXP |
LCT protein results in increased hydrolysis of Fucose |
CTD |
PMID:14701853 |
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NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation multiple interactions |
ISO |
baohuoside I results in decreased phosphorylation of AKT1 protein baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:25119583 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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G |
Akt1s1 |
AKT1 substrate 1 |
multiple interactions decreases phosphorylation |
ISO |
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] baohuoside I results in decreased phosphorylation of AKT1S1 protein |
CTD |
PMID:25119583 |
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NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases expression |
EXP |
baohuoside I results in increased expression of ALPL mRNA |
CTD |
PMID:17764702 |
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NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
baohuoside I results in increased expression of BAX protein |
CTD |
PMID:22687635 |
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NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
baohuoside I results in decreased expression of BCL2 protein |
CTD |
PMID:22687635 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
EXP |
baohuoside I results in increased expression of BGLAP mRNA |
CTD |
PMID:17764702 |
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NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
decreases phosphorylation multiple interactions |
ISO |
baohuoside I results in decreased phosphorylation of BRAF protein baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein] |
CTD |
PMID:25119583 |
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NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
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G |
Casp3 |
caspase 3 |
increases cleavage increases activity |
ISO |
baohuoside I results in increased cleavage of CASP3 protein baohuoside I results in increased activity of CASP3 protein |
CTD |
PMID:19289254 PMID:22687635 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Casp8 |
caspase 8 |
increases activity |
ISO |
baohuoside I results in increased activity of CASP8 protein |
CTD |
PMID:19289254 |
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NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
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G |
Casp9 |
caspase 9 |
increases activity increases cleavage |
ISO |
baohuoside I results in increased activity of CASP9 protein baohuoside I results in increased cleavage of CASP9 protein |
CTD |
PMID:19289254 PMID:22687635 |
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NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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G |
Col1a2 |
collagen type I alpha 2 chain |
increases expression |
EXP |
baohuoside I results in increased expression of COL1A2 mRNA |
CTD |
PMID:17764702 |
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NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein] |
CTD |
PMID:25119583 |
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NCBI chr 2:68,820,616...68,895,537
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions decreases phosphorylation |
ISO |
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] baohuoside I results in decreased phosphorylation of EGFR protein |
CTD |
PMID:25119583 |
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NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases phosphorylation |
ISO |
baohuoside I results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:25119583 |
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NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] baohuoside I results in decreased phosphorylation of MAPK1 protein |
CTD |
PMID:25119583 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
ISO |
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] baohuoside I results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:25119583 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
ISO |
baohuoside I results in decreased expression of MKI67 protein |
CTD |
PMID:25119583 |
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NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions decreases phosphorylation |
ISO |
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein] baohuoside I results in decreased phosphorylation of MTOR protein |
CTD |
PMID:25119583 |
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NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
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G |
Nos2 |
nitric oxide synthase 2 |
decreases expression |
ISO |
baohuoside I results in decreased expression of NOS2 |
CTD |
PMID:19289254 |
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NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
baohuoside I results in increased cleavage of PARP1 protein Dinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein] |
CTD |
PMID:19289254 PMID:22687635 |
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NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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G |
Pdpk1 |
3-phosphoinositide dependent protein kinase-1 |
decreases phosphorylation |
ISO |
baohuoside I results in decreased phosphorylation of PDPK1 protein |
CTD |
PMID:25119583 |
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NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression multiple interactions |
ISO |
baohuoside I results in decreased expression of PTGS2 [baohuoside I results in decreased expression of PTGS2] which results in decreased abundance of Dinoprostone; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein] |
CTD |
PMID:19289254 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
increases expression |
EXP |
baohuoside I results in increased expression of TNFRSF11B mRNA |
CTD |
PMID:17764702 |
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NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
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G |
Tnfsf11 |
TNF superfamily member 11 |
decreases expression |
EXP |
baohuoside I results in decreased expression of TNFSF11 mRNA |
CTD |
PMID:17764702 |
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NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
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G |
Vegfa |
vascular endothelial growth factor A |
decreases expression |
ISO |
baohuoside I results in decreased expression of VEGFA |
CTD |
PMID:19289254 |
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NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
phosphoramidon inhibits the reaction [AGT protein results in increased expression of EDNRA protein] |
CTD |
PMID:15007106 |
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NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] |
CTD |
PMID:15177934 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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G |
Ece1 |
endothelin converting enzyme 1 |
multiple interactions |
EXP |
EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]]; phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]; phosphoramidon inhibits the reaction [Indomethacin results in increased expression of ECE1 protein] |
CTD |
PMID:11145282 PMID:16280098 |
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NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
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G |
Edn1 |
endothelin 1 |
decreases expression multiple interactions |
EXP |
phosphoramidon results in decreased expression of EDN1 protein EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]]; EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased expression of EDN1 protein]]; phosphoramidon inhibits the reaction [Indomethacin results in increased expression of EDN1 protein] |
CTD |
PMID:11145282 PMID:16280098 PMID:16391412 |
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NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
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G |
Ednra |
endothelin receptor type A |
multiple interactions |
EXP |
phosphoramidon inhibits the reaction [AGT protein results in increased expression of EDNRA protein]; phosphoramidon inhibits the reaction [Phenylephrine results in increased expression of EDNRA protein] |
CTD |
PMID:15007106 |
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NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
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G |
Ednrb |
endothelin receptor type B |
increases expression |
EXP |
phosphoramidon results in increased expression of EDNRB protein |
CTD |
PMID:15007106 |
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NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] |
CTD |
PMID:15177934 |
|
NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
EXP |
phosphoramidon inhibits the reaction [Morphine results in decreased expression of ICAM1 protein alternative form] |
CTD |
PMID:10070497 |
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NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Kel |
Kell metallo-endopeptidase (Kell blood group) |
multiple interactions |
ISO |
KEL protein alternative form binds to and affects the metabolism of phosphoramidon |
CTD |
PMID:15769748 |
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NCBI chr 4:70,979,504...70,996,920
Ensembl chr 4:70,979,504...70,996,395
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G |
Lep |
leptin |
decreases expression |
EXP |
phosphoramidon results in decreased expression of LEP protein |
CTD |
PMID:16391412 |
|
NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:15177934 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:15177934 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mme |
membrane metallo-endopeptidase |
multiple interactions |
EXP |
phosphoramidon inhibits the reaction [Morphine results in increased activity of MME protein] |
CTD |
PMID:10070497 |
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NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
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G |
Nts |
neurotensin |
multiple interactions |
ISO |
phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein]; phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:15177934 |
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NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
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G |
Sell |
selectin L |
multiple interactions |
EXP |
phosphoramidon inhibits the reaction [Morphine results in decreased expression of SELL protein alternative form] |
CTD |
PMID:10070497 |
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NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
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G |
Tac1 |
tachykinin, precursor 1 |
multiple interactions |
EXP |
[TAC1 protein co-treated with phosphoramidon] results in increased uptake of Oxygen |
CTD |
PMID:9808699 |
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NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Rhamnose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] |
CTD |
PMID:2827574 |
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NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
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