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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:deoxycortisol
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Accession:CHEBI:23618 term browser browse the term
Definition:A 3,20-dioxo steroid having the structure of cortisol but lacking one or more of its hydroxy groups.
Synonyms:related_synonym: deoxycortisols


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11-deoxycortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Cortodoxone binds to and results in increased activity of AR protein mutant form CTD PMID:11956172 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases metabolic processing
affects metabolic processing		 ISO CYP11B1 protein results in increased metabolism of Cortodoxone
CYP11B1 protein affects the metabolism of Cortodoxone		 CTD PMID:15522937 PMID:15780661 PMID:15985365 PMID:16030167 PMID:16054388 More... NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases metabolic processing
affects metabolic processing		 ISO CYP11B2 protein results in increased metabolism of Cortodoxone
CYP11B2 protein affects the metabolism of Cortodoxone		 CTD PMID:15743198 PMID:19900470 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects binding ISO Cortodoxone binds to NR3C1 protein CTD PMID:15705660 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases activity ISO Cortodoxone results in increased activity of NR3C2 protein CTD PMID:15780662 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      application 19741
        anti-inflammatory agent 16638
          anti-inflammatory drug 14985
            cortisol 276
              deoxycortisol 5
                11-deoxycortisol 5
                18-hydroxy-11-deoxycortisol 0
                21-deoxycortisol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            heteroorganic entity 19559
                              organochalcogen compound 19317
                                organooxygen compound 19231
                                  carbonyl compound 18945
                                    ketone 17194
                                      oxyketone 8915
                                        alpha-oxyketone 8915
                                          alpha-hydroxy ketone 8915
                                            primary alpha-hydroxy ketone 7797
                                              cortisol 276
                                                deoxycortisol 5
                                                  11-deoxycortisol 5
                                                  18-hydroxy-11-deoxycortisol 0
                                                  21-deoxycortisol 0
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