CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 4-amino-1,2-oxazolidin-3-one
Accession: CHEBI:23503
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Definition: A member of the class of oxazolidines that is isoxazoldin-3-one which is substituted at position 4 by an amino group.
Synonyms: related_synonym: Formula=C3H6N2O2; InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6); InChIKey=DYDCUQKUCUHJBH-UHFFFAOYSA-N; SMILES=NC1CONC1=O; cycloserine
xref: CAS:68-39-3; KEGG:C06682
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Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions
ISO
Cycloserine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
CTD
PMID:34915026
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
Cycloserine inhibits the reaction [resveratrol results in increased expression of DDIT3 protein]
CTD
PMID:24264887
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Egr1
early growth response 1
increases expression
EXP
Cycloserine results in increased expression of EGR1 protein
CTD
PMID:19144966
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
EXP
Cycloserine promotes the reaction [Clozapine results in increased expression of FOS mRNA]
CTD
PMID:12464447
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Homer1
homer scaffold protein 1
multiple interactions
EXP
Cycloserine inhibits the reaction [Clozapine results in increased expression of HOMER1 mRNA]; Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA]
CTD
PMID:12464447
NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
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Mapk1
mitogen activated protein kinase 1
multiple interactions
EXP
Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]
CTD
PMID:11903061
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions
EXP
Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]
CTD
PMID:11903061
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
Cycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]
CTD
PMID:24264887
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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