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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-methylthioamphetamine
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Accession:CHEBI:233986 term browser browse the term
Synonyms:related_synonym: 1-(4-methylsulfanylphenyl)propan-2-amine;   para-methylthioamphetamine
 xref: CAS:14116-06-4;   HMDB:HMDB0246519
 xref_mesh: MESH:C078956
 xref: kegg.compound:C22804;   wikipedia.en:https\://en.wikipedia.org/wiki/4-Methylthioamphetamine
 chemrof_formula: C10H15NS
 chemrof_smiles: CSc1ccc(CC(C)N)cc1
 chemrof_inchi: InChI=1S/C10H15NS/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3
 chemrof_inchikey: OLEWMKVPSUCNLG-UHFFFAOYSA-N


show annotations for term's descendants           Sort by:
4-methylthioamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 increases expression
multiple interactions 		ISO 4-methylthioamphetamine results in increased expression of BAK1 protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 protein 		CTD PMID:23820845 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein
4-methylthioamphetamine results in increased expression of BAX mRNA; 4-methylthioamphetamine results in increased expression of BAX protein 		CTD PMID:23820845 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression 		ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein
4-methylthioamphetamine results in increased expression of BBC3 mRNA; 4-methylthioamphetamine results in increased expression of BBC3 protein 		CTD PMID:23820845 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO 4-methylthioamphetamine results in decreased expression of BCL2 mRNA
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2 mRNA 		CTD PMID:23820845 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression 		ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2L1 mRNA
4-methylthioamphetamine results in decreased expression of BCL2L1 mRNA 		CTD PMID:23820845 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
multiple interactions 		ISO 4-methylthioamphetamine results in increased expression of BCL2L11 mRNA; 4-methylthioamphetamine results in increased expression of BCL2L11 protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein 		CTD PMID:23820845 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression 		ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form
4-methylthioamphetamine results in increased expression of BID mRNA; 4-methylthioamphetamine results in increased expression of BID protein modified form 		CTD PMID:23820845 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        pharmacological role 19772
          neurotransmitter agent 16568
            serotonergic drug 4424
              4-methylthioamphetamine 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      p-block molecular entity 20796
                        carbon group molecular entity 20724
                          organic molecular entity 20706
                            4-methylthioamphetamine 7
paths to the root