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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:compatible osmolytes
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Accession:CHEBI:23366 term browser browse the term



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1D-myo-inositol 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYSLTR2 cysteinyl leukotriene receptor 2 multiple interactions EXP [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased chemical synthesis of inositol 1-phosphate CTD PMID:33288675 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression EXP inositol 1-phosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
5-oxo-L-proline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DEK DEK proto-oncogene multiple interactions EXP DEK protein results in decreased chemical synthesis of and results in increased uptake of Pyrrolidonecarboxylic Acid CTD PMID:28558019 NCBI chr 6:18,223,860...18,264,541
Ensembl chr 6:18,223,860...18,264,548
JBrowse link
G INS insulin multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Pyrrolidonecarboxylic Acid analog CTD PMID:26820058 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
captopril term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme multiple interactions
decreases activity
ISO
EXP
Captopril inhibits the reaction [Pregabalin results in increased expression of ACE protein]
Captopril inhibits the reaction [AGT protein results in increased expression of ACE mRNA]; Captopril inhibits the reaction [AGT protein results in increased expression of ACE protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of ACE mRNA]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of ACE protein]
Captopril results in decreased activity of ACE protein
CTD PMID:26851370 PMID:31629013 PMID:33007385 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 decreases response to substance
multiple interactions
EXP
ISO
ACE2 gene SNP results in decreased susceptibility to Captopril
Captopril inhibits the reaction [AGT protein results in decreased expression of ACE2 mRNA]; Captopril inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of ACE2 mRNA]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of ACE2 protein]
Captopril inhibits the reaction [Pregabalin results in decreased expression of ACE2 protein]
CTD PMID:17473847 PMID:31629013 PMID:33007385 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO
EXP
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]
Captopril inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; Captopril inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]
CTD PMID:31181250 PMID:33007385 NCBI chr10:88,935,074...88,991,397
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G AGT angiotensinogen multiple interactions ISO
EXP
Captopril inhibits the reaction [Pregabalin results in decreased expression of AGT protein]
Captopril inhibits the reaction [AGT protein results in decreased abundance of angiotensin I (1-7)]; Captopril inhibits the reaction [AGT protein results in decreased expression of ACE2 mRNA]; Captopril inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]; Captopril inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]; Captopril inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]; Captopril inhibits the reaction [AGT protein results in increased expression of ACE mRNA]; Captopril inhibits the reaction [AGT protein results in increased expression of ACE protein]; Captopril inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; Captopril inhibits the reaction [AGT protein results in increased expression of AGT protein]; Captopril inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]; Captopril inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]; Captopril inhibits the reaction [AGT protein results in increased expression of VIM protein]; Captopril inhibits the reaction [LEPR protein affects the expression of AGT protein]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of AGT protein alternative form]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of AGT protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of GLI3 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of PTCH1 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI1 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI2 protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SHH protein]; [goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SMO protein]; Captopril inhibits the reaction [AGT protein results in increased expression of ACTA2 protein]
CTD PMID:28130181 PMID:31181250 PMID:31629013 PMID:33007385 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 multiple interactions ISO Captopril inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein]
Captopril inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]; Captopril inhibits the reaction [LEPR protein affects the expression of AGTR1A mRNA]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of AGTR1 protein]
CTD PMID:28130181 PMID:31629013 PMID:33007385 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G BDKRB2 bradykinin receptor B2 multiple interactions ISO Captopril inhibits the reaction [LEPR protein affects the expression of BDKRB2 protein] CTD PMID:28130181 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G CA2 carbonic anhydrase 2 multiple interactions ISO Captopril promotes the reaction [LEPR protein affects the expression of CAR2 mRNA] CTD PMID:28130181 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CALB1 calbindin 1 multiple interactions ISO Captopril promotes the reaction [LEPR protein affects the expression of CALB1 protein] CTD PMID:28130181 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
JBrowse link
G CDH1 cadherin 1 multiple interactions ISO Captopril inhibits the reaction [AGT protein results in decreased expression of CDH1 protein]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:33007385 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions ISO Captopril inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of COL3A1 protein] CTD PMID:33007385 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G GLI1 GLI family zinc finger 1 multiple interactions EXP
ISO
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI1 protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein]
CTD PMID:31181250 NCBI chr12:57,459,785...57,472,451
Ensembl chr12:57,459,785...57,472,268
JBrowse link
G GLI2 GLI family zinc finger 2 multiple interactions ISO
EXP
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI2 protein]
CTD PMID:31181250 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653
JBrowse link
G GLI3 GLI family zinc finger 3 multiple interactions ISO
EXP
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in decreased expression of GLI3 protein]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of GLI3 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of GLI3 protein]
CTD PMID:31181250 NCBI chr 7:41,960,949...42,237,209
Ensembl chr 7:41,960,949...42,264,100
JBrowse link
G LEPR leptin receptor multiple interactions
affects response to substance
ISO Captopril inhibits the reaction [LEPR protein affects the expression of AGT protein]; Captopril inhibits the reaction [LEPR protein affects the expression of AGTR1A mRNA]; Captopril inhibits the reaction [LEPR protein affects the expression of BDKRB2 protein]; Captopril inhibits the reaction [LEPR protein affects the expression of PTH protein]; Captopril inhibits the reaction [LEPR protein affects the expression of VEGFA mRNA]; Captopril promotes the reaction [LEPR protein affects the expression of CALB1 protein]; Captopril promotes the reaction [LEPR protein affects the expression of CAR2 mRNA]; Captopril promotes the reaction [LEPR protein affects the expression of MMP9 mRNA]; Captopril promotes the reaction [LEPR protein affects the expression of RUNX2 mRNA]; Captopril promotes the reaction [LEPR protein affects the expression of VDR protein]
LEPR protein affects the susceptibility to Captopril
CTD PMID:28130181 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor multiple interactions ISO Captopril inhibits the reaction [Pregabalin results in decreased expression of MAS1 protein]
Captopril inhibits the reaction [AGT protein results in decreased expression of MAS1 protein]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of MAS1 protein]
CTD PMID:31629013 PMID:33007385 NCBI chr 6:159,890,988...159,917,447
Ensembl chr 6:159,890,988...159,917,447
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO Captopril promotes the reaction [LEPR protein affects the expression of MMP9 mRNA] CTD PMID:28130181 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NPPB natriuretic peptide B multiple interactions ISO Captopril inhibits the reaction [Pregabalin results in increased expression of NPPB protein] CTD PMID:31629013 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO Captopril inhibits the reaction [Pregabalin results in decreased expression of PRKACA protein] CTD PMID:31629013 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G PTCH1 patched 1 multiple interactions EXP
ISO
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in decreased expression of PTCH1 protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in decreased expression of PTCH1 protein]; Captopril inhibits the reaction [Silicon Dioxide results in decreased expression of PTCH1 protein]
CTD PMID:31181250 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057
JBrowse link
G PTH parathyroid hormone multiple interactions ISO Captopril inhibits the reaction [LEPR protein affects the expression of PTH protein] CTD PMID:28130181 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions ISO Captopril promotes the reaction [LEPR protein affects the expression of RUNX2 mRNA] CTD PMID:28130181 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SHH sonic hedgehog signaling molecule multiple interactions EXP
ISO
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SHH protein]
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of SHH protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of SHH protein]
CTD PMID:31181250 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SMO smoothened, frizzled class receptor multiple interactions ISO
EXP
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of SMO protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of SMO protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of SMO protein]
CTD PMID:31181250 NCBI chr 7:129,188,633...129,213,548
Ensembl chr 7:129,188,633...129,213,545
JBrowse link
G VDR vitamin D receptor multiple interactions ISO Captopril promotes the reaction [LEPR protein affects the expression of VDR protein] CTD PMID:28130181 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO Captopril inhibits the reaction [LEPR protein affects the expression of VEGFA mRNA] CTD PMID:28130181 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIM vimentin multiple interactions ISO Captopril inhibits the reaction [AGT protein results in increased expression of VIM protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of VIM protein] CTD PMID:33007385 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
clindamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
increases expression
EXP Clindamycin results in increased expression of and results in increased activity of CYP3A4 protein
Clindamycin results in increased expression of CYP3A4 mRNA
CTD PMID:18505790 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 affects expression EXP Clindamycin affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HLA-E major histocompatibility complex, class I, E affects expression EXP Clindamycin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr 6:30,489,508...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
G MMP13 matrix metallopeptidase 13 increases expression EXP Clindamycin results in increased expression of MMP13 mRNA CTD PMID:20338993 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
clindamycin phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PON1 paraoxonase 1 decreases activity EXP
ISO
clindamycin phosphate results in decreased activity of PON1 protein CTD PMID:16880604 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
D-mannitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA] CTD PMID:15327746 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ACACB acetyl-CoA carboxylase beta decreases expression ISO Mannitol results in decreased expression of ACACB mRNA CTD PMID:25270620 NCBI chr12:109,112,666...109,268,226
Ensembl chr12:109,116,595...109,268,226
JBrowse link
G ACLY ATP citrate lyase increases expression ISO Mannitol results in increased expression of ACLY mRNA CTD PMID:25270620 NCBI chr17:41,866,916...41,930,542
Ensembl chr17:41,866,917...41,930,542
JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 increases expression ISO Mannitol results in increased expression of ADAMTS18 mRNA CTD PMID:25270620 NCBI chr16:77,282,128...77,435,034
Ensembl chr16:77,247,813...77,435,034
JBrowse link
G AIDA axin interactor, dorsalization associated decreases expression ISO Mannitol results in decreased expression of AIDA mRNA CTD PMID:25270620 NCBI chr 1:222,668,013...222,712,895
Ensembl chr 1:222,668,013...222,713,210
JBrowse link
G AIRE autoimmune regulator decreases expression ISO Mannitol results in decreased expression of AIRE mRNA CTD PMID:25270620 NCBI chr21:44,285,876...44,298,648
Ensembl chr21:44,285,838...44,298,648
JBrowse link
G AQP9 aquaporin 9 increases uptake ISO AQP9 protein results in increased uptake of Mannitol CTD PMID:9733774 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
JBrowse link
G ARHGAP1 Rho GTPase activating protein 1 increases expression ISO Mannitol results in increased expression of ARHGAP1 mRNA CTD PMID:25270620 NCBI chr11:46,677,077...46,700,660
Ensembl chr11:46,677,080...46,700,619
JBrowse link
G ARR3 arrestin 3 increases expression ISO Mannitol results in increased expression of ARR3 mRNA CTD PMID:25270620 NCBI chr  X:70,268,334...70,281,840
Ensembl chr  X:70,268,305...70,281,840
JBrowse link
G BAD BCL2 associated agonist of cell death increases phosphorylation
multiple interactions
ISO Mannitol results in increased phosphorylation of BAD protein
wortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein]
CTD PMID:15786717 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein] CTD PMID:29803612 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBOX1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO Mannitol results in decreased expression of BBOX1 mRNA CTD PMID:25270620 NCBI chr11:27,040,705...27,127,809
Ensembl chr11:27,040,725...27,127,809
JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression ISO Mannitol results in increased expression of BCL2 protein CTD PMID:15786717 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CABLES2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Mannitol results in decreased expression of CABLES2 mRNA CTD PMID:25270620 NCBI chr20:62,388,634...62,407,285
Ensembl chr20:62,388,632...62,407,285
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
EXP IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein] CTD PMID:10567913 PMID:12011046 PMID:29803612 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 increases activity EXP Mannitol results in increased activity of CASP9 protein CTD PMID:12011046 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CBX1 chromobox 1 increases expression ISO Mannitol results in increased expression of CBX1 mRNA CTD PMID:25270620 NCBI chr17:48,070,059...48,101,478
Ensembl chr17:48,070,052...48,101,478
JBrowse link
G CCDC127 coiled-coil domain containing 127 decreases expression ISO Mannitol results in decreased expression of CCDC127 mRNA CTD PMID:25270620 NCBI chr 5:196,868...218,153
Ensembl chr 5:196,868...218,153
JBrowse link
G CCN3 cellular communication network factor 3 decreases expression ISO Mannitol results in decreased expression of CCN3 mRNA CTD PMID:25270620 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434
JBrowse link
G CKAP5 cytoskeleton associated protein 5 increases expression ISO Mannitol results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr11:46,743,048...46,846,280
Ensembl chr11:46,743,048...46,846,308
JBrowse link
G CLCN3 chloride voltage-gated channel 3 affects response to substance EXP CLCN3 protein affects the susceptibility to Mannitol deficiency CTD PMID:22108225 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673
JBrowse link
G CTNNA2 catenin alpha 2 decreases expression ISO Mannitol results in decreased expression of CTNNA2 mRNA CTD PMID:25270620 NCBI chr 2:79,505,054...80,648,788
Ensembl chr 2:79,185,231...80,648,861
JBrowse link
G DBH dopamine beta-hydroxylase increases expression ISO Mannitol results in increased expression of DBH mRNA CTD PMID:25270620 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DCTN2 dynactin subunit 2 increases expression ISO Mannitol results in increased expression of DCTN2 mRNA CTD PMID:25270620 NCBI chr12:57,530,051...57,547,216
Ensembl chr12:57,529,633...57,547,224
JBrowse link
G DEFB4B defensin beta 4B decreases expression ISO Mannitol results in decreased expression of DEFB7 mRNA CTD PMID:25270620 NCBI chr 8:7,414,855...7,416,863
Ensembl chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716
JBrowse link
G DGKA diacylglycerol kinase alpha increases expression ISO Mannitol results in increased expression of DGKA mRNA CTD PMID:25270620 NCBI chr12:55,931,091...55,954,023
Ensembl chr12:55,927,319...55,954,027
JBrowse link
G ELF2 E74 like ETS transcription factor 2 increases expression ISO Mannitol results in increased expression of ELF2 mRNA CTD PMID:25270620 NCBI chr 4:139,057,220...139,177,218
Ensembl chr 4:139,028,112...139,177,218
JBrowse link
G FAM185A family with sequence similarity 185 member A increases expression ISO Mannitol results in increased expression of FAM185A mRNA CTD PMID:25270620 NCBI chr 7:102,748,999...102,850,723
Ensembl chr 7:102,748,971...102,809,225
JBrowse link
G FAM222A family with sequence similarity 222 member A decreases expression ISO Mannitol results in decreased expression of FAM222A mRNA CTD PMID:25270620 NCBI chr12:109,713,825...109,770,509
Ensembl chr12:109,713,825...109,770,495
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Mannitol results in increased expression of FOS mRNA CTD PMID:11557636 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G GAL3ST2 galactose-3-O-sulfotransferase 2 decreases expression ISO Mannitol results in decreased expression of GAL3ST2 mRNA CTD PMID:25270620 NCBI chr 2:241,776,822...241,804,287
Ensembl chr 2:241,776,822...241,804,287
JBrowse link
G GAS2L2 growth arrest specific 2 like 2 decreases expression ISO Mannitol results in decreased expression of GAS2L2 mRNA CTD PMID:25270620 NCBI chr17:35,744,511...35,753,239
Ensembl chr17:35,744,511...35,753,239
JBrowse link
G GPC6 glypican 6 increases expression ISO Mannitol results in increased expression of GPC6 mRNA CTD PMID:25270620 NCBI chr13:93,226,807...94,408,020
Ensembl chr13:93,226,807...94,408,020
JBrowse link
G GPR19 G protein-coupled receptor 19 decreases expression ISO Mannitol results in decreased expression of GPR19 mRNA CTD PMID:25270620 NCBI chr12:12,659,691...12,717,786
Ensembl chr12:12,660,890...12,696,207
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO Mannitol results in increased expression of HMOX1 mRNA CTD PMID:11592956 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Mannitol results in increased expression of HPRT mRNA CTD PMID:25270620 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G HRH2 histamine receptor H2 increases expression ISO Mannitol results in increased expression of HRH2 mRNA CTD PMID:25270620 NCBI chr 5:175,657,762...175,710,756
Ensembl chr 5:175,658,030...175,710,756
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 protein] CTD PMID:16285992 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein] CTD PMID:10567913 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL6 interleukin 6 multiple interactions ISO Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Rotenone inhibits the reaction [Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] CTD PMID:23867654 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Mannitol results in increased expression of JUN mRNA CTD PMID:11557636 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member increases expression ISO Mannitol results in increased expression of KHDC3 mRNA CTD PMID:25270620 NCBI chr 6:73,362,658...73,364,171
Ensembl chr 6:73,362,658...73,364,171
JBrowse link
G KRTAP11-1 keratin associated protein 11-1 increases expression ISO Mannitol results in increased expression of KRTAP11-1 mRNA CTD PMID:25270620 NCBI chr21:30,880,644...30,881,580
Ensembl chr21:30,880,644...30,881,580
JBrowse link
G LSM6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Mannitol results in decreased expression of LSM6 mRNA CTD PMID:25270620 NCBI chr 4:146,175,703...146,204,436
Ensembl chr 4:146,175,703...146,200,000
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] CTD PMID:16510265 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,544
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 NCBI chr19:4,090,321...4,124,184
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK1 protein] CTD PMID:10910949 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 NCBI chr10:48,306,673...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MTA2 metastasis associated 1 family member 2 increases expression ISO Mannitol results in increased expression of MTA2 mRNA CTD PMID:25270620 NCBI chr11:62,593,214...62,601,865
Ensembl chr11:62,593,214...62,601,865
JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation ISO Mannitol results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
JBrowse link
G MYLK3 myosin light chain kinase 3 increases expression ISO Mannitol results in increased expression of MYLK3 mRNA CTD PMID:25270620 NCBI chr16:46,702,282...46,763,246
Ensembl chr16:46,702,282...46,790,407
JBrowse link
G NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 increases expression ISO Mannitol results in increased expression of NAALAD2 mRNA CTD PMID:25270620 NCBI chr11:90,131,693...90,193,577
Ensembl chr11:90,131,515...90,192,894
JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 decreases expression ISO Mannitol results in decreased expression of NDUFA13 mRNA CTD PMID:25270620 NCBI chr19:19,516,225...19,528,198
Ensembl chr19:19,515,736...19,529,054
JBrowse link
G NFAT5 nuclear factor of activated T cells 5 increases expression ISO Mannitol results in increased expression of NFAT5 mRNA CTD PMID:23867654 NCBI chr16:69,565,952...69,704,654
Ensembl chr16:69,565,094...69,704,666
JBrowse link
G NKG7 natural killer cell granule protein 7 increases expression ISO Mannitol results in increased expression of NKG7 mRNA CTD PMID:25270620 NCBI chr19:51,371,616...51,372,688
Ensembl chr19:51,371,606...51,372,701
JBrowse link
G NPPA natriuretic peptide A increases expression EXP Mannitol results in increased expression of NPPA protein CTD PMID:2177369 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NTS neurotensin increases transport ISO NTS protein results in increased transport of Mannitol CTD PMID:11208724 NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992
JBrowse link
G OAT ornithine aminotransferase multiple interactions ISO Mannitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976
JBrowse link
G PCP2 Purkinje cell protein 2 increases expression ISO Mannitol results in increased expression of PCP2 mRNA CTD PMID:25270620 NCBI chr19:7,631,614...7,637,026
Ensembl chr19:7,631,611...7,633,719
JBrowse link
G PDCD4 programmed cell death 4 increases expression
decreases expression
EXP Mannitol results in increased expression of PDCD4 mRNA
Mannitol results in decreased expression of PDCD4 mRNA
CTD PMID:21873647 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
JBrowse link
G PLCL2 phospholipase C like 2 decreases expression ISO Mannitol results in decreased expression of PLCL2 mRNA CTD PMID:25270620 NCBI chr 3:16,802,691...17,090,606
Ensembl chr 3:16,802,651...17,090,604
JBrowse link
G PLEKHO1 pleckstrin homology domain containing O1 increases expression ISO Mannitol results in increased expression of PLEKHO1 mRNA CTD PMID:25270620 NCBI chr 1:150,149,565...150,160,065
Ensembl chr 1:150,149,183...150,164,720
JBrowse link
G POU1F1 POU class 1 homeobox 1 increases expression ISO Mannitol results in increased expression of POU1F1 mRNA CTD PMID:25270620 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584
JBrowse link
G PPP1R10 protein phosphatase 1 regulatory subunit 10 decreases expression ISO Mannitol results in decreased expression of PPP1R10 mRNA CTD PMID:25270620 NCBI chr 6:30,600,400...30,618,607
Ensembl chr 6:30,600,413...30,618,612
JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit increases expression ISO Mannitol results in increased expression of PPP4C mRNA CTD PMID:25270620 NCBI chr16:30,075,994...30,085,377
Ensembl chr16:30,075,978...30,085,376
JBrowse link
G PRKCB protein kinase C beta multiple interactions EXP Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein] CTD PMID:16285992 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCD protein kinase C delta multiple interactions EXP Mannitol inhibits the reaction [Glucose results in increased expression of PRKCD protein] CTD PMID:16285992 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PTGER1 prostaglandin E receptor 1 increases expression ISO Mannitol results in increased expression of PTGER1 mRNA CTD PMID:12888618 NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
JBrowse link
G PTGER4 prostaglandin E receptor 4 decreases expression ISO Mannitol results in decreased expression of PTGER4 mRNA CTD PMID:12888618 NCBI chr 5:40,679,915...40,740,936
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein]; Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein CTD PMID:12011046 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G RBL1 RB transcriptional corepressor like 1 decreases expression ISO Mannitol results in decreased expression of RBL1 mRNA CTD PMID:25270620 NCBI chr20:36,996,349...37,096,029
Ensembl chr20:36,996,349...37,095,997
JBrowse link
G RBP2 retinol binding protein 2 decreases expression ISO Mannitol results in decreased expression of RBP2 mRNA CTD PMID:25270620 NCBI chr 3:139,452,884...139,476,516
Ensembl chr 3:139,452,884...139,480,747
JBrowse link
G RGL3 ral guanine nucleotide dissociation stimulator like 3 increases expression ISO Mannitol results in increased expression of RGL3 mRNA CTD PMID:25270620 NCBI chr19:11,394,060...11,419,314
Ensembl chr19:11,384,341...11,419,328
JBrowse link
G SAMD10 sterile alpha motif domain containing 10 decreases expression ISO Mannitol results in decreased expression of SAMD10 mRNA CTD PMID:25270620 NCBI chr20:63,974,113...63,980,788
Ensembl chr20:63,974,116...63,980,008
JBrowse link
G SBSN suprabasin decreases expression ISO Mannitol results in decreased expression of SBSN mRNA CTD PMID:25270620 NCBI chr19:35,523,367...35,528,371
Ensembl chr19:35,523,367...35,528,351
JBrowse link
G SELE selectin E multiple interactions EXP Mannitol inhibits the reaction [Glucose results in increased expression of SELE mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of SELE protein] CTD PMID:16285992 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
JBrowse link
G SGSM3 small G protein signaling modulator 3 decreases expression ISO Mannitol results in decreased expression of SGSM3 mRNA CTD PMID:25270620 NCBI chr22:40,370,584...40,410,289
Ensembl chr22:40,370,591...40,410,289
JBrowse link
G SLC12A1 solute carrier family 12 member 1 increases activity
multiple interactions
ISO Mannitol results in increased activity of SLC12A1 protein
[Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water
CTD PMID:12433675 NCBI chr15:48,206,302...48,304,078
Ensembl chr15:48,178,438...48,304,078
JBrowse link
G SLC2A8 solute carrier family 2 member 8 decreases expression ISO Mannitol results in decreased expression of SLC2A8 mRNA CTD PMID:25270620 NCBI chr 9:127,397,140...127,407,898
Ensembl chr 9:127,397,138...127,408,424
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] CTD PMID:16510265 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G STX8 syntaxin 8 decreases expression ISO Mannitol results in decreased expression of STX8 mRNA CTD PMID:25270620 NCBI chr17:9,250,471...9,575,894
Ensembl chr17:9,250,471...9,576,591
JBrowse link
G TIMD4 T cell immunoglobulin and mucin domain containing 4 decreases expression ISO Mannitol results in decreased expression of TIMD4 mRNA CTD PMID:25270620 NCBI chr 5:156,919,292...156,963,226
Ensembl chr 5:156,919,292...156,963,226
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Quartz results in increased secretion of TNF protein] CTD PMID:19298665 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 increases expression EXP Mannitol results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 6:137,866,317...137,883,312
Ensembl chr 6:137,867,214...137,883,312
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPD52 tumor protein D52 decreases expression
increases expression
EXP Mannitol results in decreased expression of TPD52 mRNA
Mannitol results in increased expression of TPD52 mRNA
CTD PMID:21873647 NCBI chr 8:79,918,717...80,171,564
Ensembl chr 8:80,034,745...80,231,232
JBrowse link
G TRIML1 tripartite motif family like 1 increases expression ISO Mannitol results in increased expression of TRIML1 mRNA CTD PMID:25270620 NCBI chr 4:188,137,229...188,150,768
Ensembl chr 4:188,139,441...188,147,743
JBrowse link
G ULBP1 UL16 binding protein 1 increases expression ISO Mannitol results in increased expression of ULBP1 mRNA CTD PMID:25270620 NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 protein] CTD PMID:16285992 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G WDR20 WD repeat domain 20 decreases expression ISO Mannitol results in decreased expression of WDR20 mRNA CTD PMID:25270620 NCBI chr14:102,139,423...102,224,686
Ensembl chr14:102,139,503...102,224,847
JBrowse link
G ZG16 zymogen granule protein 16 decreases expression ISO Mannitol results in decreased expression of ZG16 mRNA CTD PMID:25270620 NCBI chr16:29,760,804...29,782,973
Ensembl chr16:29,778,256...29,782,973
JBrowse link
G ZNF205 zinc finger protein 205 decreases expression ISO Mannitol results in decreased expression of ZFP13 mRNA CTD PMID:25270620 NCBI chr16:3,112,586...3,120,517
Ensembl chr16:3,112,560...3,120,517
JBrowse link
domoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator increases expression
increases localization
multiple interactions
EXP
ISO
domoic acid results in increased expression of BAX mRNA
domoic acid results in increased localization of BAX protein
Carbachol inhibits the reaction [domoic acid results in increased localization of BAX protein]
CTD PMID:18293405 PMID:19200344 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator affects expression EXP domoic acid affects the expression of BCL2 mRNA CTD PMID:18293405 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
ISO Carbachol inhibits the reaction [domoic acid results in increased activity of CASP3 protein] CTD PMID:19200344 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression ISO domoic acid results in increased expression of GCLC mRNA; domoic acid results in increased expression of GCLC protein CTD PMID:23315585 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
decreases response to substance
affects response to substance
ISO domoic acid results in increased expression of GCLM mRNA; domoic acid results in increased expression of GCLM protein
[GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to 2,3-dimethoxy-1,4-naphthoquinone; [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to Hydrogen Peroxide; GCLM protein results in decreased susceptibility to domoic acid; GCLM results in decreased susceptibility to domoic acid
GCLM affects the susceptibility to domoic acid
CTD PMID:17804861 PMID:19200344 PMID:23315585 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 increases phosphorylation ISO domoic acid results in increased phosphorylation of GRIA1 protein CTD PMID:19564213 NCBI chr 5:153,490,670...153,813,873
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G PVALB parvalbumin increases expression ISO domoic acid results in increased expression of PVALB protein CTD PMID:26797589 NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479
JBrowse link
G WDR35 WD repeat domain 35 increases expression
multiple interactions
ISO domoic acid results in increased expression of WDR35 mRNA; domoic acid results in increased expression of WDR35 protein
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [domoic acid results in increased expression of WDR35 protein]; Edaravone inhibits the reaction [domoic acid results in increased expression of WDR35 protein]
CTD PMID:23289926 NCBI chr 2:19,910,260...19,990,105
Ensembl chr 2:19,910,263...19,990,105
JBrowse link
fosinopril term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 decreases response to substance EXP ABCC1 protein results in decreased susceptibility to Fosinopril CTD PMID:22095822 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,138...16,143,257
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 decreases response to substance
multiple interactions
increases export
EXP
ISO
ABCC2 protein results in decreased susceptibility to Fosinopril
ABCC2 protein affects the reaction [Fosinopril affects the export of Methotrexate]
desloratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]; Loratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]; Methotrexate inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]
CTD PMID:22095822 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ADIPOR2 adiponectin receptor 2 increases expression ISO fosinopril increases expression of adipor2 mRNA in rat liver RGD PMID:19076162 RGD:2307264 NCBI chr12:1,691,059...1,788,674
Ensembl chr12:1,688,574...1,788,674
JBrowse link
G AFP alpha fetoprotein multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29859236 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AGT angiotensinogen decreases expression ISO Fosinopril results in decreased expression of AGT protein CTD PMID:12411096 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 multiple interactions ISO Fosinopril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA] CTD PMID:17803470 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G CCND1 cyclin D1 multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA] CTD PMID:29859236 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein] CTD PMID:29859236 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G KL klotho increases expression ISO Fosinopril results in increased expression of KL mRNA; Fosinopril results in increased expression of KL protein CTD PMID:21051829 NCBI chr13:33,016,063...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of MMP2 protein] CTD PMID:29859236 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO Fosinopril results in decreased expression of MMP9 mRNA; Fosinopril results in decreased expression of MMP9 protein
[Valsartan co-treated with Fosinopril] results in decreased expression of MMP9 mRNA; [Valsartan co-treated with Fosinopril] results in decreased expression of MMP9 protein
CTD PMID:21051829 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in decreased expression of NFKB1 protein] CTD PMID:29859236 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G NOS3 nitric oxide synthase 3 affects expression ISO Fosinopril affects the expression of NOS3 mRNA; Fosinopril affects the expression of NOS3 protein CTD PMID:18209565 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G PDE1A phosphodiesterase 1A affects expression ISO Fosinopril affects the expression of PDE1A mRNA; Fosinopril affects the expression of PDE1A protein CTD PMID:18209565 NCBI chr 2:182,136,453...182,523,375
Ensembl chr 2:182,140,036...182,523,192
JBrowse link
G PDE1C phosphodiesterase 1C affects expression ISO Fosinopril affects the expression of PDE1C mRNA; Fosinopril affects the expression of PDE1C protein CTD PMID:18209565 NCBI chr 7:31,616,777...32,428,224
Ensembl chr 7:31,751,179...32,428,131
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of RELA protein] CTD PMID:29859236 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G SERPINE1 serpin family E member 1 decreases expression
multiple interactions
ISO Fosinopril results in decreased expression of SERPINE1 mRNA; Fosinopril results in decreased expression of SERPINE1 protein
[Valsartan co-treated with Fosinopril] results in decreased expression of SERPINE1 mRNA; [Valsartan co-treated with Fosinopril] results in decreased expression of SERPINE1 protein
CTD PMID:21051829 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SLC15A1 solute carrier family 15 member 1 multiple interactions EXP Fosinopril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr13:98,683,801...98,752,672
Ensembl chr13:98,683,801...98,752,672
JBrowse link
G SLC15A2 solute carrier family 15 member 2 multiple interactions ISO Fosinopril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr 3:121,894,401...121,944,188
Ensembl chr 3:121,894,401...121,944,188
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of TGFB1 protein] CTD PMID:29859236 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 decreases expression
multiple interactions
ISO Fosinopril results in decreased expression of TIMP1 mRNA; Fosinopril results in decreased expression of TIMP1 protein
[Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 mRNA; [Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 protein
CTD PMID:21051829 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of TNF protein] CTD PMID:29859236 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of VEGFA protein] CTD PMID:29859236 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
kainic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression ISO Kainic Acid results in increased expression of ABCB1A mRNA; Kainic Acid results in increased expression of ABCB1A protein CTD PMID:14706787 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression ISO Kainic Acid results in increased expression of ABCG2 mRNA CTD PMID:17997037 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACO2 aconitase 2 multiple interactions
decreases activity
ISO 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein] CTD PMID:11520895 NCBI chr22:41,468,756...41,528,979
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACP1 acid phosphatase 1 decreases expression ISO Kainic Acid results in decreased expression of ACP1 mRNA CTD PMID:17997037 NCBI chr 2:264,947...278,283
Ensembl chr 2:264,140...278,283
JBrowse link
G ADK adenosine kinase increases expression ISO Kainic Acid results in increased expression of ADK mRNA CTD PMID:17997037 NCBI chr10:74,151,185...74,709,300
Ensembl chr10:74,151,202...74,709,963
JBrowse link
G ADNP activity dependent neuroprotector homeobox multiple interactions
decreases expression
ISO Enzyme Inhibitors inhibits the reaction [Kainic Acid results in decreased expression of ADNP protein]
Kainic Acid results in decreased expression of ADNP mRNA; Kainic Acid results in decreased expression of ADNP protein
CTD PMID:18375135 NCBI chr20:50,888,918...50,931,437
Ensembl chr20:50,888,916...50,931,437
JBrowse link
G ADRA1B adrenoceptor alpha 1B increases response to substance ISO ADRA1B protein results in increased susceptibility to Kainic Acid CTD PMID:19125850 NCBI chr 5:159,916,482...159,989,205
Ensembl chr 5:159,865,080...159,973,012
JBrowse link
G AIF1 allograft inflammatory factor 1 increases expression
multiple interactions
ISO Kainic Acid results in increased expression of AIF1 protein
NADP inhibits the reaction [Kainic Acid results in increased expression of AIF1 protein]
CTD PMID:32057834 NCBI chr 6:31,615,212...31,617,015
Ensembl chr 6:31,615,217...31,617,021
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 increases localization
multiple interactions
ISO Kainic Acid results in increased localization of AIFM1 protein
Minocycline inhibits the reaction [Kainic Acid results in increased localization of AIFM1 protein]
CTD PMID:16469440 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein increases expression ISO Kainic Acid results in increased expression of ALOX5AP mRNA CTD PMID:19700661 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression ISO Kainic Acid results in increased expression of APAF1 mRNA CTD PMID:17997037 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA CTD PMID:16120186 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G APOE apolipoprotein E decreases expression ISO Kainic Acid results in decreased expression of APOE mRNA CTD PMID:17997037 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ARC activity regulated cytoskeleton associated protein increases expression ISO Kainic Acid results in increased expression of ARC mRNA; Kainic Acid results in increased expression of ARC protein CTD PMID:17632064 PMID:30557575 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G ATF7IP activating transcription factor 7 interacting protein decreases expression ISO Kainic Acid results in decreased expression of ATF7IP mRNA CTD PMID:19700661 NCBI chr12:14,365,640...14,502,935
Ensembl chr12:14,365,676...14,502,931
JBrowse link
G ATG5 autophagy related 5 multiple interactions
increases expression
ISO NADP inhibits the reaction [Kainic Acid results in increased expression of ATG5 protein] CTD PMID:32057834 NCBI chr 6:106,184,476...106,325,789
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G B4GALT2 beta-1,4-galactosyltransferase 2 decreases expression ISO Kainic Acid results in decreased expression of B4GALT2 mRNA CTD PMID:17997037 NCBI chr 1:43,979,210...43,991,171
Ensembl chr 1:43,978,943...43,991,170
JBrowse link
G BAG3 BAG cochaperone 3 increases expression ISO Kainic Acid results in increased expression of BAG3 mRNA CTD PMID:19700661 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Kainic Acid results in increased expression of BAX mRNA; Kainic Acid results in increased expression of BAX protein
oridonin inhibits the reaction [Kainic Acid results in increased expression of BAX mRNA]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]]
Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of BAX protein]
CTD PMID:18711747 PMID:19700661 PMID:25453207 PMID:31430510 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
ISO 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]
Kainic Acid results in decreased expression of BCL2 mRNA
oridonin inhibits the reaction [Kainic Acid results in decreased expression of BCL2 mRNA]
CTD PMID:25453207 PMID:31430510 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions
increases expression
ISO [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]
Kainic Acid results in increased expression of BDNF mRNA; Kainic Acid results in increased expression of BDNF protein
CTD PMID:1641125 PMID:9073163 PMID:11279263 PMID:16166269 PMID:17827730 More... NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 multiple interactions
increases expression
ISO NADP inhibits the reaction [Kainic Acid results in increased expression of BECN1 protein] CTD PMID:32057834 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G C1QB complement C1q B chain increases expression ISO Kainic Acid results in increased expression of C1QB mRNA CTD PMID:17997037 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
JBrowse link
G C4B complement C4B (Chido blood group) increases expression ISO Kainic Acid results in increased expression of C4B mRNA CTD PMID:17997037 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
JBrowse link
G CALB1 calbindin 1 decreases expression ISO Kainic Acid results in decreased expression of CALB1 mRNA CTD PMID:17997037 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
JBrowse link
G CAMK4 calcium/calmodulin dependent protein kinase IV decreases expression ISO Kainic Acid results in decreased expression of CAMK4 mRNA CTD PMID:17997037 NCBI chr 5:111,223,583...111,498,503
Ensembl chr 5:111,223,653...111,494,886
JBrowse link
G CAPNS1 calpain small subunit 1 increases expression ISO Kainic Acid results in increased expression of CAPNS1 mRNA CTD PMID:19700661 NCBI chr19:36,140,066...36,150,353
Ensembl chr19:36,139,953...36,150,353
JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Kainic Acid results in increased activity of CASP3 protein
oridonin inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of CASP3 protein]
Kainic Acid results in increased cleavage of CASP3 protein
Kainic Acid results in increased expression of CASP3 mRNA; Kainic Acid results in increased expression of CASP3 protein
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]]; Minocycline inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]; Valproic Acid inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]
CTD PMID:16469440 PMID:18711747 PMID:19700661 PMID:25453207 PMID:31430510 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CAT catalase decreases expression
decreases activity
multiple interactions
ISO Kainic Acid results in decreased expression of CAT mRNA; Kainic Acid results in decreased expression of CAT protein
Kainic Acid results in decreased activity of CAT protein
oridonin inhibits the reaction [Kainic Acid results in decreased activity of CAT protein]
CTD PMID:29208536 PMID:31430510 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCK cholecystokinin decreases expression ISO Kainic Acid results in decreased expression of CCK protein CTD PMID:7774662 NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression ISO Kainic Acid results in increased expression of CCL2 mRNA CTD PMID:19700661 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCNE1 cyclin E1 increases expression ISO Kainic Acid results in increased expression of CCNE1 protein CTD PMID:12941380 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CD68 CD68 molecule increases expression ISO Kainic Acid results in increased expression of CD68 mRNA CTD PMID:19700661 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
JBrowse link
G CDC42 cell division cycle 42 increases expression ISO Kainic Acid results in increased expression of CDC42 mRNA CTD PMID:19700661 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,025,511...22,101,360
JBrowse link
G CDH13 cadherin 13 increases expression ISO Kainic Acid results in increased expression of CDH13 mRNA CTD PMID:17997037 NCBI chr16:82,626,823...83,800,640
Ensembl chr16:82,626,965...83,800,640
JBrowse link
G CDK2 cyclin dependent kinase 2 increases expression ISO Kainic Acid results in increased expression of CDK2 protein CTD PMID:12941380 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 increases expression ISO Kainic Acid results in increased expression of CEACAM1 mRNA CTD PMID:17997037 NCBI chr19:42,507,306...42,528,482
Ensembl chr19:42,507,304...42,561,234
JBrowse link
G CHGB chromogranin B increases expression ISO Kainic Acid results in increased expression of CHGB mRNA CTD PMID:9427505 NCBI chr20:5,911,510...5,925,353
Ensembl chr20:5,911,510...5,925,353
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 increases expression ISO Kainic Acid results in increased expression of CITED2 mRNA CTD PMID:19700661 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CNR1 cannabinoid receptor 1 increases expression ISO Kainic Acid results in increased expression of CNR1 mRNA CTD PMID:22079489 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNRIP1 cannabinoid receptor interacting protein 1 increases expression ISO Kainic Acid results in increased expression of CNRIP1 mRNA CTD PMID:22079489 NCBI chr 2:68,284,171...68,319,949
Ensembl chr 2:68,284,171...68,320,051
JBrowse link
G COL1A1 collagen type I alpha 1 chain increases expression ISO Kainic Acid results in increased expression of COL1A1 mRNA CTD PMID:17997037 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 increases expression ISO Kainic Acid results in increased expression of CRHR1 mRNA CTD PMID:12093084 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G CTSB cathepsin B multiple interactions
increases expression
ISO NADP inhibits the reaction [Kainic Acid results in increased expression of CTSB protein] CTD PMID:32057834 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CTSD cathepsin D increases expression
multiple interactions
ISO Kainic Acid results in increased expression of CTSD protein
NADP inhibits the reaction [Kainic Acid results in increased expression of CTSD protein]
CTD PMID:32057834 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CTSS cathepsin S increases expression ISO Kainic Acid results in increased expression of CTSS mRNA; Kainic Acid results in increased expression of CTSS protein CTD PMID:17997037 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
JBrowse link
G CTSZ cathepsin Z increases expression ISO Kainic Acid results in increased expression of CTSZ mRNA CTD PMID:17997037 NCBI chr20:58,995,185...59,007,254
Ensembl chr20:58,985,686...59,008,238
JBrowse link
G CYCS cytochrome c, somatic increases localization
increases expression
multiple interactions
ISO Kainic Acid results in increased localization of CYCS protein
Kainic Acid results in increased expression of CYCS mRNA
Minocycline inhibits the reaction [Kainic Acid results in increased localization of CYCS protein]
CTD PMID:16469440 PMID:19700661 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G DGCR6 DiGeorge syndrome critical region gene 6 decreases expression ISO Kainic Acid results in decreased expression of DGCR6 mRNA CTD PMID:17997037 NCBI chr22:18,906,320...18,912,088
Ensembl chr22:18,906,028...18,914,238
JBrowse link
G DHX36 DEAH-box helicase 36 increases expression ISO Kainic Acid results in increased expression of DHX36 mRNA CTD PMID:17997037 NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487
JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein increases expression ISO Kainic Acid results in increased expression of DIABLO mRNA CTD PMID:19700661 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,663...122,227,456
JBrowse link
G DRD2 dopamine receptor D2 decreases response to substance ISO DRD2 protein results in decreased susceptibility to Kainic Acid CTD PMID:11860278 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G EGR1 early growth response 1 decreases expression
affects expression
ISO Kainic Acid results in decreased expression of EGR1 mRNA
Kainic Acid affects the expression of EGR1 mRNA
CTD PMID:17997037 PMID:19700661 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 increases expression ISO Kainic Acid results in increased expression of EIF4A3 protein CTD PMID:17632064 NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151
JBrowse link
G EMC3 ER membrane protein complex subunit 3 decreases expression ISO Kainic Acid results in decreased expression of EMC3 mRNA CTD PMID:17997037 NCBI chr 3:9,962,682...10,011,118
Ensembl chr 3:9,962,537...10,011,116
JBrowse link
G EN2 engrailed homeobox 2 affects response to substance
decreases expression
ISO EN2 protein affects the susceptibility to Kainic Acid
Kainic Acid results in decreased expression of EN2 mRNA
CTD PMID:19186208 NCBI chr 7:155,458,129...155,464,831
Ensembl chr 7:155,458,129...155,464,831
JBrowse link
G ENC1 ectodermal-neural cortex 1 decreases expression ISO Kainic Acid results in decreased expression of ENC1 mRNA CTD PMID:17997037 NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
JBrowse link
G EPO erythropoietin multiple interactions EXP EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]; EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of CASP3 protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]] CTD PMID:18711747 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G EPOR erythropoietin receptor multiple interactions
decreases expression
EXP
ISO
EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]] CTD PMID:18711747 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
JBrowse link
G ETFB electron transfer flavoprotein subunit beta decreases expression ISO Kainic Acid results in decreased expression of ETFB mRNA CTD PMID:17997037 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388
JBrowse link
G FBXW5 F-box and WD repeat domain containing 5 decreases expression ISO Kainic Acid results in decreased expression of FBXW5 mRNA CTD PMID:17997037 NCBI chr 9:136,940,435...136,944,774
Ensembl chr 9:136,940,435...136,944,738
JBrowse link
G FGF2 fibroblast growth factor 2 increases expression ISO Kainic Acid results in increased expression of FGF2 mRNA CTD PMID:7649223 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGF5 fibroblast growth factor 5 increases expression ISO Kainic Acid results in increased expression of FGF5 mRNA CTD PMID:7649223 NCBI chr 4:80,266,588...80,291,017
Ensembl chr 4:80,266,639...80,336,680
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 increases expression ISO Kainic Acid results in increased expression of FGFR1 mRNA CTD PMID:7649223 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone inhibits the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; [Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of FOS protein; Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of FOS protein]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]
Kainic Acid results in increased expression of FOS mRNA; Kainic Acid results in increased expression of FOS protein
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; [Phenytoin co-treated with Drugs, Chinese Herbal] inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; Diazepam inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]
Kainic Acid results in decreased expression of FOS mRNA
CTD PMID:7655348 PMID:7887109 PMID:8417141 PMID:8758711 PMID:15723099 More... NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Kainic Acid results in increased expression of FOSL2 mRNA CTD PMID:19700661 NCBI chr 2:28,392,855...28,417,317
Ensembl chr 2:28,392,448...28,417,317
JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 decreases expression ISO Kainic Acid results in decreased expression of FXYD1 mRNA CTD PMID:17997037 NCBI chr19:35,137,206...35,143,109
Ensembl chr19:35,138,824...35,143,109
JBrowse link
G GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression
multiple interactions
ISO Kainic Acid results in increased expression of GABRB1 mRNA
Quercetin inhibits the reaction [Kainic Acid results in increased expression of GABRB1 mRNA]
CTD PMID:27386150 NCBI chr 4:46,993,560...47,438,409
Ensembl chr 4:46,993,723...47,426,447
JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 multiple interactions
increases expression
ISO Quercetin inhibits the reaction [Kainic Acid results in increased expression of GABRB3 mRNA] CTD PMID:27386150 NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,546...26,939,539
JBrowse link
G GAD1 glutamate decarboxylase 1 increases expression ISO Kainic Acid results in increased expression of GAD1 mRNA CTD PMID:16797850 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
JBrowse link
G GAD2 glutamate decarboxylase 2 increases expression ISO Kainic Acid results in increased expression of GAD2 mRNA CTD PMID:16797850 NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression ISO Kainic Acid results in increased expression of GADD45A mRNA; Kainic Acid results in increased expression of GADD45A protein CTD PMID:20955365 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta decreases expression ISO Kainic Acid results in decreased expression of GADD45B mRNA CTD PMID:17997037 NCBI chr19:2,476,127...2,478,259
Ensembl chr19:2,476,122...2,478,259
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma decreases expression ISO Kainic Acid results in decreased expression of GADD45G mRNA CTD PMID:17997037 NCBI chr 9:89,605,009...89,606,555
Ensembl chr 9:89,605,012...89,606,555
JBrowse link
G GAP43 growth associated protein 43 multiple interactions
increases expression
ISO Dizocilpine Maleate inhibits the reaction [Kainic Acid results in increased expression of GAP43 mRNA]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of GAP43 mRNA] CTD PMID:8774942 NCBI chr 3:115,623,510...115,721,485
Ensembl chr 3:115,623,510...115,721,490
JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Kainic Acid results in increased expression of GCNT2 mRNA CTD PMID:17997037 NCBI chr 6:10,521,283...10,629,368
Ensembl chr 6:10,492,223...10,629,368
JBrowse link
G GFAP glial fibrillary acidic protein increases expression
multiple interactions
ISO
EXP
Kainic Acid results in increased expression of GFAP mRNA; Kainic Acid results in increased expression of GFAP protein
NADP inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]
PTGS2 affects the reaction [Kainic Acid results in increased expression of GFAP mRNA]
CTD PMID:17997037 PMID:18711747 PMID:19700661 PMID:21589914 PMID:22790971 More... NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GLUL glutamate-ammonia ligase decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GLUL mRNA
oridonin inhibits the reaction [Kainic Acid results in decreased expression of GLUL mRNA]
CTD PMID:31430510 NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206
JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression ISO Kainic Acid results in decreased expression of GPX1 protein CTD PMID:29208536 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions
decreases expression
ISO 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of GRIA1 protein]; Kainic Acid binds to and results in increased activity of GRIA1 protein; Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA1 protein]
Kainic Acid results in decreased expression of GRIA1 mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]
Kainic Acid results in decreased expression of GRIA1 mRNA; Kainic Acid results in decreased expression of GRIA1 protein
CTD PMID:7529610 PMID:11812690 PMID:17585341 PMID:21589914 NCBI chr 5:153,490,670...153,813,873
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions
increases methylation
decreases expression
affects response to substance
ISO Kainic Acid binds to and results in increased activity of GRIA2 protein; Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA2 protein]
Kainic Acid results in increased methylation of GRIA2 gene
Kainic Acid results in decreased expression of GRIA2 mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA2 mRNA]; RG108 inhibits the reaction [Kainic Acid results in increased methylation of GRIA2 gene]
GRIA2 protein affects the susceptibility to Kainic Acid
CTD PMID:7529610 PMID:10551584 PMID:11812690 PMID:21589914 PMID:24098468 NCBI chr 4:157,220,120...157,370,583
Ensembl chr 4:157,204,182...157,366,075
JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression
multiple interactions
increases expression
ISO Kainic Acid results in decreased expression of GRIA3 mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA3 mRNA]
Kainic Acid results in increased expression of GRIA3 mRNA
CTD PMID:7529610 PMID:21589914 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915
JBrowse link
G GRIA4 glutamate ionotropic receptor AMPA type subunit 4 decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIA4 mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA4 mRNA]
CTD PMID:21589914 NCBI chr11:105,609,540...105,982,090
Ensembl chr11:105,609,994...105,982,092
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 decreases expression
increases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIK1 mRNA
Kainic Acid results in increased expression of GRIK1 mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA]
CTD PMID:21589914 PMID:29208536 NCBI chr21:29,536,933...29,939,996
Ensembl chr21:29,536,933...29,940,033
JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 increases expression
multiple interactions
ISO Kainic Acid results in increased expression of GRIK2 mRNA
[Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK2 mRNA
CTD PMID:17997037 PMID:21589914 PMID:29208536 NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:100,962,701...102,081,622
JBrowse link
G GRIK3 glutamate ionotropic receptor kainate type subunit 3 decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIK3 mRNA
[Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK3 mRNA
CTD PMID:21589914 NCBI chr 1:36,795,527...37,034,515
Ensembl chr 1:36,795,527...37,034,515
JBrowse link
G GRIK4 glutamate ionotropic receptor kainate type subunit 4 multiple interactions
decreases expression
ISO [Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK4 mRNA
Kainic Acid results in decreased expression of GRIK4 mRNA
CTD PMID:21589914 NCBI chr11:120,511,748...120,988,906
Ensembl chr11:120,511,746...120,988,906
JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions
decreases expression
ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA] CTD PMID:21589914 NCBI chr19:41,998,316...42,071,804
Ensembl chr19:41,998,321...42,069,498
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
affects expression
decreases expression
ISO celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN1 mRNA]
Kainic Acid affects the expression of GRIN1
CTD PMID:21589914 PMID:23159308 NCBI chr 9:137,139,092...137,168,759
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN2A mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2A mRNA]
CTD PMID:21589914 NCBI chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
decreases expression
ISO celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2B mRNA] CTD PMID:21589914 NCBI chr12:13,537,337...13,982,012
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN2C mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA]
CTD PMID:21589914 NCBI chr17:74,842,021...74,860,843
Ensembl chr17:74,842,023...74,861,504
JBrowse link
G GRIN2D glutamate ionotropic receptor NMDA type subunit 2D decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN2D mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA]
CTD PMID:21589914 NCBI chr19:48,393,668...48,444,937
Ensembl chr19:48,393,668...48,444,931
JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A multiple interactions
decreases expression
ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA] CTD PMID:21589914 NCBI chr 9:101,569,352...101,738,647
Ensembl chr 9:101,569,352...101,738,647
JBrowse link
G GRIN3B glutamate ionotropic receptor NMDA type subunit 3B decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN3B mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3B mRNA]
CTD PMID:21589914 NCBI chr19:1,000,419...1,009,748
Ensembl chr19:1,000,419...1,009,732
JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases activity
decreases phosphorylation
multiple interactions
ISO Kainic Acid results in decreased activity of GSK3B protein
Kainic Acid results in decreased phosphorylation of GSK3B protein
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]
CTD PMID:18619545 PMID:25453207 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases activity
ISO oridonin inhibits the reaction [Kainic Acid results in decreased activity of GSR protein] CTD PMID:31430510 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 multiple interactions
decreases expression
ISO Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]; REST mutant form inhibits the reaction [Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 mRNA]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 protein]
Kainic Acid results in decreased expression of HCN1 mRNA; Kainic Acid results in decreased expression of HCN1 protein
CTD PMID:21905079 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO Kainic Acid results in increased expression of HMOX1 mRNA CTD PMID:7655348 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HOMER1 homer scaffold protein 1 increases expression ISO Kainic Acid results in increased expression of HOMER1 mRNA CTD PMID:19700661 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134
JBrowse link
G HPCA hippocalcin decreases response to substance ISO HPCA protein results in decreased susceptibility to Kainic Acid CTD PMID:15607944 NCBI chr 1:32,885,965...32,894,646
Ensembl chr 1:32,885,994...32,898,441
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Kainic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:17997037 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein; Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]; GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein] CTD PMID:16686654 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Kainic Acid results in decreased expression of IDI1 mRNA CTD PMID:17997037 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119
JBrowse link
G IL10 interleukin 10 decreases expression ISO Kainic Acid results in decreased expression of IL10 protein CTD PMID:15591643 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL12A interleukin 12A affects response to substance ISO IL12A protein affects the susceptibility to Kainic Acid CTD PMID:15474355 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
JBrowse link
G IL1B interleukin 1 beta increases secretion
increases expression
multiple interactions
ISO Kainic Acid results in increased secretion of IL1B protein
Kainic Acid results in increased expression of IL1B mRNA; Kainic Acid results in increased expression of IL1B protein
PTGS2 affects the reaction [Kainic Acid results in increased expression of IL1B mRNA]
Minocycline inhibits the reaction [Kainic Acid results in increased secretion of IL1B protein]; oridonin inhibits the reaction [Kainic Acid results in increased expression of IL1B protein]
CTD PMID:7655348 PMID:11306611 PMID:21589914 PMID:31430510 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 increases response to substance
multiple interactions
increases expression
ISO IL6 protein results in increased susceptibility to Kainic Acid
oridonin inhibits the reaction [Kainic Acid results in increased expression of IL6 protein]
Kainic Acid results in increased expression of IL6 mRNA
PTGS2 affects the reaction [Kainic Acid results in increased expression of IL6 mRNA]
CTD PMID:12836160 PMID:21589914 PMID:31430510 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGAM integrin subunit alpha M increases expression
multiple interactions
ISO Kainic Acid results in increased expression of ITGAM mRNA
PTGS2 affects the reaction [Kainic Acid results in increased expression of ITGAM mRNA]
CTD PMID:21589914 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G JAGN1 jagunal homolog 1 decreases expression ISO Kainic Acid results in decreased expression of JAGN1 mRNA CTD PMID:17997037 NCBI chr 3:9,890,610...9,894,349
Ensembl chr 3:9,890,574...9,894,349
JBrowse link
G JAK2 Janus kinase 2 multiple interactions
decreases expression
EXP
ISO
EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]] CTD PMID:18711747 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; Diazepam inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of JUN protein]
Kainic Acid results in increased expression of JUN mRNA; Kainic Acid results in increased expression of JUN protein
CTD PMID:8417141 PMID:15723099 PMID:17827730 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
ISO Kainic Acid results in decreased expression of JUNB mRNA
Kainic Acid results in increased expression of JUNB mRNA
CTD PMID:17997037 PMID:19700661 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G KALRN kalirin RhoGEF kinase increases expression ISO Kainic Acid results in increased expression of KALRN mRNA CTD PMID:19700661 NCBI chr 3:124,033,341...124,726,325
Ensembl chr 3:124,033,369...124,726,325
JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 increases expression ISO Kainic Acid results in increased expression of KCNC2 protein CTD PMID:7643197 NCBI chr12:75,040,078...75,209,839
Ensembl chr12:75,040,077...75,209,839
JBrowse link
G KCNC4 potassium voltage-gated channel subfamily C member 4 decreases expression ISO Kainic Acid results in decreased expression of KCNC4 protein CTD PMID:21905079 NCBI chr 1:110,210,314...110,282,649
Ensembl chr 1:110,210,314...110,283,100
JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 increases response to substance EXP KCNQ2 protein mutant form results in increased susceptibility to Kainic Acid CTD PMID:26910900 NCBI chr20:63,400,208...63,472,655
Ensembl chr20:63,400,208...63,472,677
JBrowse link
G KIF20A kinesin family member 20A decreases expression ISO Kainic Acid results in decreased expression of KIF20A mRNA CTD PMID:17997037 NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
JBrowse link
G KLF10 Kruppel like factor 10 decreases expression ISO Kainic Acid results in decreased expression of KLF10 mRNA CTD PMID:17997037 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
JBrowse link
G KNG1 kininogen 1 multiple interactions ISO Kainic Acid promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form] CTD PMID:7807204 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G KRAS KRAS proto-oncogene, GTPase increases expression ISO Kainic Acid results in increased expression of KRAS mRNA CTD PMID:19700661 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LEP leptin decreases response to substance ISO LEP protein results in decreased susceptibility to Kainic Acid CTD PMID:17993459 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LMO1 LIM domain only 1 decreases expression ISO Kainic Acid results in decreased expression of LMO1 mRNA CTD PMID:17997037 NCBI chr11:8,224,304...8,268,787
Ensembl chr11:8,224,309...8,268,716
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO NADP inhibits the reaction [Kainic Acid results in increased expression of MAP1LC3B protein modified form] CTD PMID:32057834 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAP2 microtubule associated protein 2 multiple interactions
increases expression
ISO PTGS2 affects the reaction [Kainic Acid results in increased expression of MAP2 mRNA] CTD PMID:21589914 NCBI chr 2:209,424,047...209,734,118
Ensembl chr 2:209,424,047...209,734,118
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Kainic Acid results in decreased expression of MAP3K5 mRNA CTD PMID:17997037 NCBI chr 6:136,557,046...136,793,098
Ensembl chr 6:136,557,046...136,792,477
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases expression ISO Kainic Acid results in increased expression of MAPK3 mRNA CTD PMID:17997037 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAST3 microtubule associated serine/threonine kinase 3 decreases expression ISO Kainic Acid results in decreased expression of MAST3 mRNA CTD PMID:17997037 NCBI chr19:18,097,778...18,151,692
Ensembl chr19:18,097,793...18,151,692
JBrowse link
G MMP9 matrix metallopeptidase 9 increases activity
multiple interactions
ISO Kainic Acid results in increased activity of MMP9 protein
MMP9 protein affects the reaction [Kainic Acid results in decreased expression of NCAM1 protein modified form]
CTD PMID:30772382 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPDZ multiple PDZ domain crumbs cell polarity complex component affects response to substance ISO MPDZ protein affects the susceptibility to Kainic Acid CTD PMID:14960011 NCBI chr 9:13,105,296...13,279,692
Ensembl chr 9:13,105,706...13,279,692
JBrowse link
G MPEG1 macrophage expressed 1 increases expression ISO Kainic Acid results in increased expression of MPEG1 mRNA CTD PMID:17997037 NCBI chr11:59,208,510...59,212,927
Ensembl chr11:59,208,510...59,212,927
JBrowse link
G MSMO1 methylsterol monooxygenase 1 decreases expression ISO Kainic Acid results in decreased expression of MSMO1 mRNA CTD PMID:17997037 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
JBrowse link
G MT1A metallothionein 1A increases expression ISO Kainic Acid results in increased expression of MT1A mRNA CTD PMID:7655348 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1X metallothionein 1X decreases response to substance ISO MT1 protein results in decreased susceptibility to Kainic Acid CTD PMID:10947810 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A decreases response to substance ISO MT2 protein results in decreased susceptibility to Kainic Acid CTD PMID:10947810 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MYO5B myosin VB decreases expression ISO Kainic Acid results in decreased expression of MYO5B mRNA CTD PMID:17997037 NCBI chr18:49,822,789...50,195,147
Ensembl chr18:49,822,789...50,195,147
JBrowse link
G MYO9A myosin IXA increases expression ISO Kainic Acid results in increased expression of MYO9A mRNA CTD PMID:17997037 NCBI chr15:71,822,291...72,118,577
Ensembl chr15:71,822,291...72,118,577
JBrowse link
G NAIP NLR family apoptosis inhibitory protein increases expression ISO Kainic Acid results in increased expression of NAIP mRNA; Kainic Acid results in increased expression of NAIP protein CTD PMID:12547647 PMID:15046874 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339
JBrowse link
G NCAM1 neural cell adhesion molecule 1 decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of NCAM1 mRNA
MMP9 protein affects the reaction [Kainic Acid results in decreased expression of NCAM1 protein modified form]
CTD PMID:19700661 PMID:30772382 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,247...113,278,436
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization ISO Kainic Acid affects the localization of NFE2L2 protein CTD PMID:18619545 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NOS1 nitric oxide synthase 1 multiple interactions
decreases expression
increases expression
ISO 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of NOS1 protein]
Kainic Acid results in increased expression of NOS1 mRNA; Kainic Acid results in increased expression of NOS1 protein
CTD PMID:17585341 PMID:18375135 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions
ISO Kainic Acid results in increased expression of NOS2 mRNA
Kainic Acid results in increased expression of NOS2 mRNA; Kainic Acid results in increased expression of NOS2 protein
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]
PTGS2 affects the reaction [Kainic Acid results in increased expression of NOS2 mRNA]
CTD PMID:17827730 PMID:18375135 PMID:21589914 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NPY neuropeptide Y decreases response to substance
multiple interactions
increases expression
ISO NPY protein results in decreased susceptibility to Kainic Acid
Thiopental inhibits the reaction [Kainic Acid results in increased expression of NPY mRNA]
CTD PMID:9427505 PMID:15451008 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862
JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 decreases expression
increases expression
ISO Kainic Acid results in decreased expression of NR4A1 mRNA
Kainic Acid results in increased expression of NR4A1 mRNA
CTD PMID:17997037 PMID:19700661 NCBI chr12:52,022,832...52,059,507
Ensembl chr12:52,022,832...52,059,507
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 increases expression ISO Kainic Acid results in increased expression of NR4A2 mRNA
Kainic Acid results in increased expression of NR4A2 protein
CTD PMID:19700661 PMID:24813937 NCBI chr 2:156,324,432...156,332,724
Ensembl chr 2:156,324,437...156,342,348
JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 increases expression ISO Kainic Acid results in increased expression of NR4A3 mRNA CTD PMID:19700661 NCBI chr 9:99,821,885...99,866,893
Ensembl chr 9:99,821,855...99,866,891
JBrowse link
G NRP2 neuropilin 2 affects response to substance ISO NRP2 protein affects the susceptibility to Kainic Acid CTD PMID:18657176 NCBI chr 2:205,682,501...205,798,131
Ensembl chr 2:205,681,990...205,798,133
JBrowse link
G NTN1 netrin 1 increases expression ISO Kainic Acid results in increased expression of NTN1 mRNA CTD PMID:19700661 NCBI chr17:9,021,510...9,244,000
Ensembl chr17:9,021,510...9,244,000
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Kainic Acid results in increased expression of NTRK2 mRNA CTD PMID:19700661 NCBI chr 9:84,668,458...85,027,070
Ensembl chr 9:84,668,551...85,027,054
JBrowse link
G NUDCD2 NudC domain containing 2 increases expression ISO Kainic Acid results in increased expression of NUDCD2 mRNA CTD PMID:17997037 NCBI chr 5:163,446,526...163,460,102
Ensembl chr 5:163,446,526...163,460,102
JBrowse link
G NUDT4 nudix hydrolase 4 increases expression ISO Kainic Acid results in increased expression of NUDT4 mRNA CTD PMID:17997037 NCBI chr12:93,377,925...93,408,146
Ensembl chr12:93,377,883...93,408,146
JBrowse link
G OTX2 orthodenticle homeobox 2 decreases expression ISO Kainic Acid results in decreased expression of OTX2 mRNA CTD PMID:19700661 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693
JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 decreases expression ISO Kainic Acid results in decreased expression of PAK3 mRNA CTD PMID:19700661 NCBI chr  X:110,944,324...111,227,361
Ensembl chr  X:110,944,285...111,227,361
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases activity ISO Kainic Acid results in increased activity of PARP1 protein CTD PMID:28704930 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PDYN prodynorphin multiple interactions
increases expression
ISO Diazepam inhibits the reaction [Kainic Acid results in increased expression of PDYN mRNA]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of PDYN mRNA]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of PDYN mRNA] CTD PMID:8417141 NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285
JBrowse link
G PENK proenkephalin multiple interactions
increases expression
ISO Diazepam inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]; Thiopental inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA] CTD PMID:8417141 PMID:9427505 NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671
JBrowse link
G PICK1 protein interacting with PRKCA 1 decreases expression ISO Kainic Acid results in decreased expression of PICK1 mRNA CTD PMID:17997037 NCBI chr22:38,056,311...38,075,704
Ensembl chr22:38,056,311...38,075,701
JBrowse link
G PKP2 plakophilin 2 decreases expression ISO Kainic Acid results in decreased expression of PKP2 mRNA CTD PMID:17997037 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,755...32,896,777
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 decreases expression ISO Kainic Acid results in decreased expression of PLOD3 mRNA CTD PMID:17997037 NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
JBrowse link
G PPIF peptidylprolyl isomerase F increases response to substance ISO PPIF results in increased susceptibility to Kainic Acid CTD PMID:21378209 NCBI chr10:79,347,469...79,355,334
Ensembl chr10:79,347,469...79,355,334
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B increases expression ISO Kainic Acid results in increased expression of PPP1R9B protein CTD PMID:17443789 NCBI chr17:50,133,737...50,150,677
Ensembl chr17:50,133,737...50,150,677
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases response to substance
increases expression
ISO [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; oridonin inhibits the reaction [Kainic Acid results in increased expression of PTGS2 protein]
[PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Dinoprost; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Dinoprostone; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Prostaglandin D2; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Thromboxane B2; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of GFAP mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of IL1B mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of IL6 mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of ITGAM mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of MAP2 mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of RELA mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of TNF mRNA]
Kainic Acid results in increased expression of PTGS2; Kainic Acid results in increased expression of PTGS2 mRNA; Kainic Acid results in increased expression of PTGS2 protein
CTD PMID:11168565 PMID:12618123 PMID:17827730 PMID:18834901 PMID:19700661 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G QKI QKI, KH domain containing RNA binding increases expression ISO Kainic Acid results in increased expression of QK mRNA CTD PMID:17997037 NCBI chr 6:163,414,486...163,578,592
Ensembl chr 6:163,414,000...163,578,592
JBrowse link
G RAC1 Rac family small GTPase 1 increases expression ISO Kainic Acid results in increased expression of RAC1 mRNA CTD PMID:19700661 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein increases expression ISO Kainic Acid results in increased expression of RAD23A mRNA CTD PMID:19700661 NCBI chr19:12,945,846...12,953,642
Ensembl chr19:12,945,855...12,953,642
JBrowse link
G RASD1 ras related dexamethasone induced 1 decreases expression ISO Kainic Acid results in decreased expression of RASD1 mRNA CTD PMID:17997037 NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395
JBrowse link
G RBFOX1 RNA binding fox-1 homolog 1 increases response to substance ISO RBFOX1 gene mutant form results in increased susceptibility to Kainic Acid CTD PMID:21623373 NCBI chr16:5,239,752...7,713,343
Ensembl chr16:5,239,802...7,713,340
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO PTGS2 affects the reaction [Kainic Acid results in increased expression of RELA mRNA] CTD PMID:21589914 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G REST RE1 silencing transcription factor increases expression
multiple interactions
ISO Kainic Acid results in increased expression of REST protein
Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]; REST mutant form inhibits the reaction [Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 mRNA]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 protein]
CTD PMID:21905079 NCBI chr 4:56,907,900...56,935,847
Ensembl chr 4:56,907,876...56,966,808
JBrowse link
G RGS16 regulator of G protein signaling 16 decreases expression ISO Kainic Acid results in decreased expression of RGS16 mRNA CTD PMID:17997037 NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,389
JBrowse link
G RHOA ras homolog family member A increases expression ISO Kainic Acid results in increased expression of RHOA mRNA CTD PMID:19700661 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 decreases expression ISO Kainic Acid results in decreased expression of S1PR1 mRNA CTD PMID:17997037 NCBI chr 1:101,236,899...101,241,518
Ensembl chr 1:101,236,865...101,243,713
JBrowse link
G SAP30L SAP30 like decreases expression ISO Kainic Acid results in decreased expression of SAP30L mRNA CTD PMID:17997037 NCBI chr 5:154,445,969...154,461,053
Ensembl chr 5:154,445,997...154,461,053
JBrowse link
G SEMA4D semaphorin 4D increases expression ISO Kainic Acid results in increased expression of SEMA4D mRNA CTD PMID:19700661 NCBI chr 9:89,360,787...89,498,113
Ensembl chr 9:89,360,787...89,498,130
JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions
increases expression
ISO Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]; Mecamylamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]; Phentolamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SFPQ splicing factor proline and glutamine rich increases expression ISO Kainic Acid results in increased expression of SFPQ mRNA CTD PMID:17997037 NCBI chr 1:35,176,380...35,193,174
Ensembl chr 1:35,176,378...35,193,145
JBrowse link
G SIGMAR1 sigma non-opioid intracellular receptor 1 multiple interactions ISO SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]] CTD PMID:15723099 NCBI chr 9:34,634,722...34,637,787
Ensembl chr 9:34,634,722...34,637,844
JBrowse link
G SIRT1 sirtuin 1 decreases expression
increases expression
ISO Kainic Acid results in decreased expression of SIRT1 protein
Kainic Acid results in increased expression of SIRT1 protein
CTD PMID:18538940 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC11A2 solute carrier family 11 member 2 increases expression ISO Kainic Acid results in increased expression of SLC11A2 CTD PMID:16552559 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
JBrowse link
G SLC1A1 solute carrier family 1 member 1 decreases expression ISO Kainic Acid results in decreased expression of SLC1A1 mRNA CTD PMID:17997037 NCBI chr 9:4,490,466...4,587,469
Ensembl chr 9:4,490,468...4,587,469
JBrowse link
G SLC1A2 solute carrier family 1 member 2 multiple interactions
increases expression
ISO [Kainic Acid co-treated with zinc chloride] results in decreased expression of SLC1A2 protein
Kainic Acid results in increased expression of SLC1A2 protein
Ceftriaxone promotes the reaction [Kainic Acid results in increased expression of SLC1A2 protein]
CTD PMID:19061913 PMID:28257918 NCBI chr11:35,251,205...35,420,058
Ensembl chr11:35,251,205...35,420,063
JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Kainic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
G SLC6A2 solute carrier family 6 member 2 increases response to substance ISO SLC6A2 protein results in increased susceptibility to Kainic Acid CTD PMID:15911120 NCBI chr16:55,655,928...55,706,192
Ensembl chr16:55,655,988...55,707,645
JBrowse link
G SLC8A3 solute carrier family 8 member A3 multiple interactions
increases expression
increases cleavage
ISO 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in increased cleavage of SLC8A3 protein]
Kainic Acid results in increased expression of SLC8A3 protein
CTD PMID:17585341 PMID:20928830 NCBI chr14:70,044,215...70,189,626
Ensembl chr14:70,044,215...70,189,070
JBrowse link
G SNRK SNF related kinase decreases expression ISO Kainic Acid results in decreased expression of SNRK mRNA CTD PMID:17997037 NCBI chr 3:43,286,512...43,351,143
Ensembl chr 3:43,286,512...43,424,764
JBrowse link
G SOD1 superoxide dismutase 1 decreases expression ISO Kainic Acid results in decreased expression of SOD1 protein CTD PMID:29208536 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 decreases expression
increases expression
ISO Kainic Acid results in decreased expression of SOD2 protein
Kainic Acid results in decreased expression of SOD2 mRNA; Kainic Acid results in decreased expression of SOD2 protein
Kainic Acid results in increased expression of SOD2 protein
CTD PMID:10686417 PMID:29208536 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 increases expression ISO Kainic Acid results in increased expression of SPTAN1 protein modified form CTD PMID:22790971 NCBI chr 9:128,552,564...128,633,662
Ensembl chr 9:128,552,558...128,633,662
JBrowse link
G SQSTM1 sequestosome 1 decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of SQSTM1 protein
NADP inhibits the reaction [Kainic Acid results in decreased expression of SQSTM1 protein]
CTD PMID:32057834 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SST somatostatin decreases expression ISO Kainic Acid results in decreased expression of SST mRNA CTD PMID:17997037 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394
JBrowse link
G TAC1 tachykinin precursor 1 decreases expression ISO Kainic Acid results in decreased expression of TAC1 protein CTD PMID:6205719 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of TIGAR protein
NADP inhibits the reaction [Kainic Acid results in decreased expression of TIGAR protein]
CTD PMID:32057834 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028
JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression
ISO PTGS2 affects the reaction [Kainic Acid results in increased expression of TNF mRNA]; TNF protein promotes the reaction [Kainic Acid results in increased uptake of Cobalt]
oridonin inhibits the reaction [Kainic Acid results in increased expression of TNF protein]
Kainic Acid results in increased expression of TNF mRNA; Kainic Acid results in increased expression of TNF protein
CTD PMID:15869941 PMID:19700661 PMID:21589914 PMID:31430510 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 increases expression ISO Kainic Acid results in increased expression of TP53 protein CTD PMID:20955365 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRH thyrotropin releasing hormone decreases expression
increases expression
ISO Kainic Acid results in decreased expression of TRH mRNA
Kainic Acid results in increased expression of TRH mRNA
CTD PMID:10443546 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935
JBrowse link
G TRHR thyrotropin releasing hormone receptor decreases expression ISO Kainic Acid results in decreased expression of TRHR protein CTD PMID:10443546 NCBI chr 8:109,086,585...109,121,565
Ensembl chr 8:109,086,585...109,121,565
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP increases expression ISO Kainic Acid results in increased expression of TYROBP mRNA CTD PMID:17997037 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 increases expression ISO Kainic Acid results in increased expression of UCHL1 protein CTD PMID:22790971 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
JBrowse link
G UHMK1 U2AF homology motif kinase 1 decreases expression ISO Kainic Acid results in decreased expression of UHMK1 mRNA CTD PMID:17997037 NCBI chr 1:162,497,174...162,529,631
Ensembl chr 1:162,497,251...162,529,631
JBrowse link
G URI1 URI1 prefoldin like chaperone increases expression ISO Kainic Acid results in increased expression of URI1 mRNA CTD PMID:17997037 NCBI chr19:29,923,650...30,016,612
Ensembl chr19:29,923,644...30,016,612
JBrowse link
G UTP3 UTP3 small subunit processome component decreases expression ISO Kainic Acid results in decreased expression of UTP3 mRNA CTD PMID:17997037 NCBI chr 4:70,688,532...70,690,551
Ensembl chr 4:70,688,532...70,690,551
JBrowse link
G VAMP7 vesicle associated membrane protein 7 decreases expression ISO Kainic Acid results in decreased expression of VAMP7 mRNA CTD PMID:19700661 NCBI chr  X:155,881,318...155,943,769
NCBI chr  Y:57,067,838...57,130,289
Ensembl chr  X:155,881,345...155,943,769
JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression ISO Kainic Acid results in decreased expression of VEGFA mRNA CTD PMID:17997037 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein increases expression ISO Kainic Acid results in increased expression of WFS1 mRNA CTD PMID:17997037 NCBI chr 4:6,260,368...6,303,265
Ensembl chr 4:6,269,849...6,303,265
JBrowse link
G XPA XPA, DNA damage recognition and repair factor increases expression ISO Kainic Acid results in increased expression of XPA mRNA CTD PMID:19700661 NCBI chr 9:97,654,398...97,697,403
Ensembl chr 9:97,674,909...97,697,340
JBrowse link
G ZCCHC7 zinc finger CCHC-type containing 7 increases expression ISO Kainic Acid results in increased expression of ZCCHC7 mRNA CTD PMID:17997037 NCBI chr 9:37,120,166...37,358,149
Ensembl chr 9:37,120,574...37,358,149
JBrowse link
lincomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-E major histocompatibility complex, class I, E affects expression EXP Lincomycin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr 6:30,489,508...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
G MR1 major histocompatibility complex, class I-related affects expression EXP Lincomycin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,374...181,061,938
JBrowse link
lisinopril dihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme decreases activity EXP Lisinopril analog results in decreased activity of ACE protein CTD PMID:22200082 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 increases expression
increases activity
ISO Lisinopril results in increased expression of ACE2 mRNA
Lisinopril results in increased activity of ACE2 protein
CTD PMID:15897343 PMID:16221218 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
Lisinopril inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein]
CTD PMID:23060470 PMID:31710167 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G AGT angiotensinogen decreases expression
decreases secretion
increases secretion
multiple interactions
affects response to substance
increases expression
EXP
ISO
Lisinopril results in decreased expression of AGT protein
Lisinopril results in decreased secretion of AGT protein
Lisinopril results in increased secretion of AGT protein alternative form
[Lisinopril co-treated with Losartan] results in increased expression of AGT mRNA
AGT gene alternative form affects the susceptibility to Lisinopril
Lisinopril results in increased expression of AGT mRNA
CTD PMID:8393685 PMID:8915971 PMID:15897343 PMID:16221218 PMID:16685205 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP Lisinopril results in decreased expression of BCL2 CTD PMID:10075388 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CD2AP CD2 associated protein multiple interactions ISO Lisinopril inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein] CTD PMID:16636307 NCBI chr 6:47,477,746...47,627,263
Ensembl chr 6:47,477,789...47,627,263
JBrowse link
G EDN1 endothelin 1 decreases secretion EXP Lisinopril results in decreased secretion of EDN1 protein CTD PMID:19079593 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G GH1 growth hormone 1 multiple interactions ISO [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] CTD PMID:20051877 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 multiple interactions ISO Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein] CTD PMID:19225054 NCBI chr 5:157,028,383...157,069,633
Ensembl chr 5:157,029,413...157,059,119
JBrowse link
G HLA-G major histocompatibility complex, class I, G affects expression EXP Lisinopril affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr 6:29,826,474...29,831,130
Ensembl chr 6:29,826,967...29,831,125
JBrowse link
G HPSE heparanase multiple interactions ISO [Spironolactone co-treated with Lisinopril] inhibits the reaction [Doxorubicin results in increased expression of HPSE protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HPSE protein] CTD PMID:19429930 NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 increases expression EXP Lisinopril results in increased expression of IGFBP1 protein CTD PMID:9663927 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein] CTD PMID:20051877 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MPO myeloperoxidase multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein] CTD PMID:23060470 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] CTD PMID:20051877 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin multiple interactions ISO Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 mRNA]; Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 protein] CTD PMID:16636307 NCBI chr 1:179,550,539...179,575,987
Ensembl chr 1:179,550,539...179,575,952
JBrowse link
G NPPA natriuretic peptide A decreases expression EXP Lisinopril results in decreased expression of NPPA protein CTD PMID:8393685 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G REN renin increases expression
multiple interactions
EXP
ISO
Lisinopril results in increased expression of REN protein
[Lisinopril co-treated with Losartan] results in increased expression of REN mRNA
Lisinopril results in increased expression of REN mRNA
CTD PMID:2550029 PMID:8915971 PMID:16221218 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] CTD PMID:20051877 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of VEGFA protein] CTD PMID:19293598 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
royal jelly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] CTD PMID:30896085 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP3 caspase 3 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] CTD PMID:30896085 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CAT catalase multiple interactions ISO royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein]
CTD PMID:20369241 PMID:30896085 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
affects binding
increases activity
EXP Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein]
royal jelly results in increased activity of ESR1 protein
CTD PMID:15946813 PMID:17287592 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions
affects binding
EXP Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:15946813 PMID:17287592 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] CTD PMID:30896085 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G TFF1 trefoil factor 1 increases expression EXP royal jelly results in increased expression of TFF1 mRNA CTD PMID:15946813 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
JBrowse link
G TP53 tumor protein p53 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] CTD PMID:30896085 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP
ISO
royal jelly results in increased expression of VEGFA mRNA CTD PMID:15946813 PMID:17287592 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25189
    role 25112
      biological role 25082
        osmolyte 2044
          compatible osmolytes 357
            D-mannitol + 92
            D-pinitol 0
            L-proline + 274
            myo-inositol + 2
paths to the root