Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cineole
go back to main search page
Accession:CHEBI:23243 term browser browse the term
Synonyms:related_synonym: cineoles



show annotations for term's descendants           Sort by:
 
1,8-cineole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of ACTR2 protein] CTD PMID:31483951 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of CDC42 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of CDC42 protein] CTD PMID:31483951 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Eucalyptol results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cttn cortactin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of CTTN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of CTTN protein] CTD PMID:31483951 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Eucalyptol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases hydroxylation
multiple interactions
ISO CYP3A4 protein results in increased hydroxylation of Eucalyptol
Eucalyptol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]
CTD PMID:15715982 PMID:18385293 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases hydroxylation ISO CYP3A5 protein results in increased hydroxylation of Eucalyptol CTD PMID:15715982 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ezr ezrin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of EZR protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of EZR protein] CTD PMID:31483951 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Eucalyptol results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]; RHOA protein inhibits the reaction [Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]] CTD PMID:31483951 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Eucalyptol results in decreased expression of HMGCR protein CTD PMID:24613879 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ICAM1 mRNA]; Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ICAM1 protein] CTD PMID:29789401 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 protein] CTD PMID:29789401 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lep leptin multiple interactions ISO Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of CTTN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of EZR protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PTK2 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PXN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SRC protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SYNPO protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of TLN1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of VCL protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased abundance of Blood Glucose]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of CDC42 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of PXN protein modified form]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RAC1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RHOA protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of ROCK1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of VCL protein modified form] CTD PMID:31483951 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK8 protein] CTD PMID:23872422 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK9 protein] CTD PMID:23872422 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Muc19 mucin 19 decreases expression ISO Eucalyptol results in decreased expression of MUC19 mRNA CTD PMID:26207629 NCBI chr 7:123,017,896...123,139,053 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides results in increased expression of MUC2 mRNA] CTD PMID:26207629 NCBI chr 1:196,796,257...196,831,740 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MUC5AC mRNA]; Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MUC5AC protein] CTD PMID:29215731 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides affects the expression of NFKBIA protein]; Eucalyptol inhibits the reaction [Lipopolysaccharides inhibits the reaction [RELA protein binds to NFKBIA protein]] CTD PMID:23872422 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of PTK2 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PTK2 protein] CTD PMID:31483951 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pxn paxillin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein]; Eucalyptol inhibits the reaction [Glucose results in increased expression of PXN protein modified form]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PXN protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of PXN protein modified form]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein]] CTD PMID:31483951 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of RAC1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RAC1 protein] CTD PMID:31483951 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Eucalyptol inhibits the reaction [Lipopolysaccharides inhibits the reaction [RELA protein binds to NFKBIA protein]] CTD PMID:23872422 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of RHOA protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of RHOA protein]; RHOA protein inhibits the reaction [Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein]]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of VCL protein]] CTD PMID:31483951 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in increased expression of ROCK1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of ROCK1 protein] CTD PMID:31483951 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Eucalyptol inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of SRC protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SRC protein] CTD PMID:31483951 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Synpo synaptopodin multiple interactions ISO Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of SYNPO protein] CTD PMID:31483951 NCBI chr18:54,048,299...54,106,388
Ensembl chr18:54,026,152...54,102,126
JBrowse link
G Tln1 talin 1 multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of TLN1 protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of TLN1 protein] CTD PMID:31483951 NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Eucalyptol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNF protein]
Eucalyptol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:23872422 PMID:26207629 PMID:29789401 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcl vinculin multiple interactions ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of VCL protein]; Eucalyptol inhibits the reaction [Glucose results in increased expression of VCL protein modified form]; Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of VCL protein]; Eucalyptol inhibits the reaction [LEP gene mutant form results in increased expression of VCL protein modified form]; RHOA protein promotes the reaction [Eucalyptol inhibits the reaction [Glucose results in decreased expression of VCL protein]] CTD PMID:31483951 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
tea tree oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO Tea Tree Oil results in increased activity of ESR1 protein CTD PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO Tea Tree Oil results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]
CTD PMID:31393563 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          volatile oil component 6580
            cineole 37
              1,4-cineole 0
              1,8-cineole + 37
              1-methyl-2-[(2-methylbenzyl)oxy]-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane + 0
              2-endo-hydroxy-1,8-cineole 0
              2-exo-hydroxy-1,4-cineole 0
              2-exo-hydroxy-1,8-cineole 0
              6-oxocineole 0
              cinmethylin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    main group molecular entity 19698
                      s-block molecular entity 19479
                        hydrogen molecular entity 19471
                          hydrides 18834
                            organic hydride 18348
                              organic fundamental parent 18348
                                hydrocarbon 18059
                                  terpene 12725
                                    terpenoid 12295
                                      monoterpenoid 1224
                                        p-menthane monoterpenoid 437
                                          cineole 37
                                            1,4-cineole 0
                                            1,8-cineole + 37
                                            1-methyl-2-[(2-methylbenzyl)oxy]-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane + 0
                                            2-endo-hydroxy-1,8-cineole 0
                                            2-exo-hydroxy-1,4-cineole 0
                                            2-exo-hydroxy-1,8-cineole 0
                                            6-oxocineole 0
                                            cinmethylin 0
paths to the root