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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chromanol
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Accession:CHEBI:23229 term browser browse the term
Definition:Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.


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(+)-alpha-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein] CTD PMID:24448832 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCD1 ATP binding cassette subfamily D member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD1 mRNA] CTD PMID:29065513 NCBI chr  X:153,724,851...153,744,755
Ensembl chr  X:153,724,856...153,744,755
JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD3 mRNA] CTD PMID:29065513 NCBI chr 1:94,418,086...94,518,663
Ensembl chr 1:94,418,389...94,518,666
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein] CTD PMID:10656290 NCBI chr11:108,116,705...108,148,822
Ensembl chr11:108,116,695...108,147,603
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:19464315 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACVRL1 activin A receptor like type 1 increases expression ISO alpha-Tocopherol results in increased expression of ACVRL1 mRNA CTD PMID:16908007 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G AGT angiotensinogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein]; alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,702,523...230,714,122
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B increases expression ISO alpha-Tocopherol results in increased expression of AKR1B1 mRNA CTD PMID:16908007 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of AKT1 protein]
CTD PMID:19351882 PMID:22343715 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327
JBrowse link
G ALB albumin multiple interactions ISO alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]] CTD PMID:17429802 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ANO6 anoctamin 6 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of ANO6 mRNA] CTD PMID:27886375 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 multiple interactions
decreases expression
ISO alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA]
alpha-Tocopherol results in decreased expression of APEX2 mRNA
CTD PMID:26332274 NCBI chr  X:55,000,363...55,009,057
Ensembl chr  X:55,000,363...55,009,057
JBrowse link
G APOA1 apolipoprotein A1 decreases expression
decreases activity
EXP
ISO
alpha-Tocopherol results in decreased expression of APOA1 mRNA; alpha-Tocopherol results in decreased expression of APOA1 protein
alpha-Tocopherol results in decreased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOB apolipoprotein B multiple interactions EXP alpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper] CTD PMID:11368321 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APP amyloid beta precursor protein multiple interactions EXP alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] CTD PMID:12684028 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ATF2 activating transcription factor 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of ATF2 protein] CTD PMID:14645110 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
JBrowse link
G BACE1 beta-secretase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,207...117,316,259
JBrowse link
G BAD BCL2 associated agonist of cell death increases expression ISO alpha-Tocopherol results in increased expression of BAD mRNA CTD PMID:26332274 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in increased expression of BAX protein]
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein]
alpha-Tocopherol results in increased expression of BAX mRNA
CTD PMID:11805214 PMID:26332274 PMID:32134168 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Endosulfan results in decreased activity of BCHE protein] CTD PMID:24299906 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
EXP
ISO
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; TNFRSF10B mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]
alpha-Tocopherol analog results in decreased expression of BCL2 mRNA; alpha-Tocopherol analog results in decreased expression of BCL2 protein
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of BCL2 protein]
CTD PMID:11805214 PMID:16005924 PMID:16135673 PMID:20686688 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression ISO alpha-Tocopherol results in decreased expression of BCL2L1 protein CTD PMID:18942769 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased expression of BDNF protein] CTD PMID:30776390 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G CANX calnexin affects localization
increases expression
ISO alpha-Tocopherol affects the localization of CANX protein
alpha-Tocopherol results in increased expression of CANX mRNA; alpha-Tocopherol results in increased expression of CANX protein
CTD PMID:16908007 NCBI chr 5:179,678,646...179,731,641
Ensembl chr 5:179,678,628...179,731,641
JBrowse link
G CASP3 caspase 3 multiple interactions
decreases activity
EXP
ISO
[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein; [alpha-Tocopherol co-treated with Tretinoin] results in increased activity of CASP3 protein; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Acetaldehyde results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP3 protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased cleavage of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein]
alpha-Tocopherol results in decreased activity of CASP3 protein
CTD PMID:12450566 PMID:14599462 PMID:14722101 PMID:15095415 PMID:17618090 PMID:17874176 PMID:17936189 PMID:21869839 PMID:22389237 PMID:23042730 PMID:29065513 PMID:29129777 PMID:30776390 PMID:31712109 PMID:32134168 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP7 caspase 7 multiple interactions EXP alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]] CTD PMID:23042730 PMID:29129777 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 increases cleavage EXP alpha-Tocopherol analog results in increased cleavage of CASP8 protein CTD PMID:20686688 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 increases cleavage
multiple interactions
EXP
ISO
alpha-Tocopherol analog results in increased cleavage of CASP9 protein
alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]
alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP9 protein
CTD PMID:20686688 PMID:21869839 PMID:31712109 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
increases activity
increases expression
ISO
EXP
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [Copper Sulfate results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
alpha-Tocopherol results in increased activity of CAT protein
alpha-Tocopherol results in increased expression of CAT protein
alpha-Tocopherol results in increased expression of CAT mRNA; alpha-Tocopherol results in increased expression of CAT protein
CTD PMID:9306888 PMID:16979807 PMID:18547560 PMID:19083475 PMID:19464315 PMID:19941068 PMID:20194575 PMID:21322096 PMID:22732938 PMID:27823922 PMID:30057697 PMID:31022331 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA] CTD PMID:27257344 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD PMID:19735175 PMID:24333275 PMID:26332274 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCND1 cyclin D1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA] CTD PMID:26332274 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND2 cyclin D2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA] CTD PMID:26332274 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
Ensembl chr12:4,269,771...4,305,353
JBrowse link
G CD36 CD36 molecule affects expression
multiple interactions
ISO alpha-Tocopherol affects the expression of CD36 mRNA
alpha-Tocopherol inhibits the reaction [[troglitazone co-treated with Ethanol] results in increased expression of CD36 protein]
CTD PMID:16407258 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
decreases expression
ISO alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]
alpha-Tocopherol results in decreased expression of CDKN1A mRNA
CTD PMID:26332274 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions EXP alpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein] CTD PMID:20363832 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CHAT choline O-acetyltransferase multiple interactions ISO [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] CTD PMID:25891525 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,665,104
Ensembl chr10:49,609,095...49,665,104
JBrowse link
G CLCN3 chloride voltage-gated channel 3 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of CLCN3 mRNA] CTD PMID:27886375 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673
JBrowse link
G CLDN2 claudin 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Potassium Dichromate affects the localization of CLDN2 protein] CTD PMID:19766176 NCBI chr  X:106,900,164...106,930,861
Ensembl chr  X:106,900,164...106,930,861
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions
increases expression
EXP alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CPT1A mRNA]; alpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA]
alpha-Tocopherol results in increased expression of CPT1A mRNA
CTD PMID:17936189 NCBI chr11:68,754,620...68,844,410
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 multiple interactions EXP [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 mRNA; [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 protein CTD PMID:15225641 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of CREB1 protein] CTD PMID:30776390 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRP C-reactive protein multiple interactions EXP [alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of CRP protein CTD PMID:18191645 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CRYAA crystallin alpha A increases expression ISO alpha-Tocopherol results in increased expression of CRYAA mRNA CTD PMID:16908007 NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805
JBrowse link
G CTSD cathepsin D increases expression ISO alpha-Tocopherol results in increased expression of CTSD protein CTD PMID:18942769 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA] CTD PMID:24333275 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA] CTD PMID:24333275 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] CTD PMID:19135038 PMID:25551565 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression
multiple interactions
ISO alpha-Tocopherol results in increased expression of CYP1A1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA]; alpha-Tocopherol results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:15665910 PMID:22389237 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases activity
multiple interactions
ISO alpha-Tocopherol results in increased activity of CYP1A2 protein
alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]
CTD PMID:15665910 PMID:26102010 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 decreases expression ISO alpha-Tocopherol results in decreased expression of CYP2B10 mRNA CTD PMID:26102010 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein] CTD PMID:26102010 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases expression
multiple interactions
ISO
EXP
alpha-Tocopherol results in increased expression of CYP2E1 mRNA
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]
CTD PMID:26332274 PMID:27919644 PMID:28062356 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression
multiple interactions
EXP
ISO
alpha-Tocopherol results in increased expression of CYP3A4 mRNA
alpha-Tocopherol results in increased expression of CYP3A11; alpha-Tocopherol results in increased expression of CYP3A11 mRNA; alpha-Tocopherol results in increased expression of CYP3A11 protein
alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP3A11 mRNA]
alpha-Tocopherol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CYP3A4 mRNA]; Galactosamine inhibits the reaction [alpha-Tocopherol results in increased expression of CYP3A4 mRNA]
CTD PMID:15649653 PMID:16008107 PMID:17936189 PMID:26102010 PMID:31102695 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 increases expression
multiple interactions
ISO
EXP
alpha-Tocopherol results in increased expression of CYP3A13 mRNA; alpha-Tocopherol results in increased expression of CYP3A13 protein
alpha-Tocopherol inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]
CTD PMID:26102010 PMID:31102695 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 multiple interactions
increases expression
EXP alpha-Tocopherol inhibits the reaction [Ethanol results in decreased expression of CYP4F2 protein]
alpha-Tocopherol results in increased expression of CYP4F2 mRNA; alpha-Tocopherol results in increased expression of CYP4F2 protein
CTD PMID:28062356 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077
JBrowse link
G DCD dermcidin multiple interactions ISO alpha-Tocopherol inhibits the reaction [DCD protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 NCBI chr12:54,644,589...54,648,365
Ensembl chr12:54,644,589...54,648,493
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]
alpha-Tocopherol analog results in increased expression of DDIT3 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased expression of DDIT3 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased expression of DDIT3 protein]
CTD PMID:20459685 PMID:20686688 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein affects localization ISO alpha-Tocopherol affects the localization of DIABLO protein CTD PMID:15582575 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,663...122,227,456
Ensembl chr12:122,207,663...122,227,456
JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation
multiple interactions
EXP alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein]
CTD PMID:20686688 NCBI chr 3:150,546,726...150,586,016
Ensembl chr 3:150,546,678...150,586,016
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G FASLG Fas ligand increases expression ISO alpha-Tocopherol results in increased expression of FASLG mRNA CTD PMID:26332274 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FBL fibrillarin decreases expression ISO alpha-Tocopherol deficiency results in decreased expression of FBL protein CTD PMID:15247049 NCBI chr19:39,834,458...39,846,395
Ensembl chr19:39,834,458...39,846,379
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 increases expression ISO alpha-Tocopherol results in increased expression of FMO1 mRNA CTD PMID:16908007 NCBI chr 1:171,248,473...171,285,978
Ensembl chr 1:171,248,471...171,285,978
JBrowse link
G FN1 fibronectin 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein] CTD PMID:9225831 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of FYN protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of FYN protein] CTD PMID:14572611 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression ISO alpha-Tocopherol results in increased expression of GADD45A mRNA CTD PMID:26332274 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions EXP [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLC mRNA CTD PMID:24530478 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions ISO
EXP
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA]
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA
CTD PMID:22389237 PMID:24530478 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GFAP glial fibrillary acidic protein increases expression ISO alpha-Tocopherol results in increased expression of GFAP protein CTD PMID:18942769 NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GNAI2 G protein subunit alpha i2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 3:50,227,068...50,259,362
Ensembl chr 3:50,226,292...50,259,362
JBrowse link
G GNAI3 G protein subunit alpha i3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO alpha-Tocopherol inhibits the reaction [beryllium nitrate results in increased activity of GPT protein] CTD PMID:17429802 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Sodium Selenite results in increased expression of GPX4 mRNA] CTD PMID:14642406 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,926...1,106,791
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein] CTD PMID:16979807 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 increases expression ISO alpha-Tocopherol results in increased expression of GSTT1 protein CTD PMID:9855024
G GUSB glucuronidase beta multiple interactions ISO alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in decreased uptake of GUSB protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of GUSB protein] CTD PMID:19135433 NCBI chr 7:65,960,684...65,982,230
Ensembl chr 7:65,960,684...65,982,215
JBrowse link
G HAL histidine ammonia-lyase increases expression ISO alpha-Tocopherol results in increased expression of HAL mRNA CTD PMID:16908007 NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
JBrowse link
G HBG2 hemoglobin subunit gamma 2 increases expression EXP alpha-Tocopherol results in increased expression of HBG2 protein CTD PMID:2606537 NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:19595682 PMID:21535577 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,362,101
JBrowse link
G HMOX1 heme oxygenase 1 affects expression
multiple interactions
EXP
ISO
alpha-Tocopherol affects the expression of HMOX1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein]; alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]
alpha-Tocopherol inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]
CTD PMID:8743975 PMID:12180188 PMID:22053912 PMID:22389237 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HP haptoglobin affects activity
multiple interactions
EXP
ISO
alpha-Tocopherol affects the activity of HP protein polymorphism
Ascorbic Acid inhibits the reaction [alpha-Tocopherol affects the activity of HP protein polymorphism]
CTD PMID:19769483 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD17B3 mRNA] CTD PMID:32134168 NCBI chr 9:96,235,306...96,313,987
Ensembl chr 9:96,235,306...96,302,176
JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD3B2 mRNA] CTD PMID:32134168 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression ISO alpha-Tocopherol results in increased expression of HSPA1B mRNA CTD PMID:16908007 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 protein] CTD PMID:22313677 PMID:25551565 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma multiple interactions ISO [alpha-Tocopherol co-treated with Lipopolysaccharides] results in increased expression of IFNG mRNA; alpha-Tocopherol results in decreased susceptibility to [IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] CTD PMID:16307444 PMID:24333275 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
JBrowse link
G IL10 interleukin 10 multiple interactions EXP
ISO
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; alpha-Tocopherol promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
[alpha-Tocopherol co-treated with Lipopolysaccharides] results in increased expression of IL10 mRNA
CTD PMID:24333275 PMID:25551565 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein] CTD PMID:15025948 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of IL1B protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of IL1B protein]; alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of IL1B mRNA]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of IL1B mRNA]
CTD PMID:19135433 PMID:19735175 PMID:26332274 PMID:31712109 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions EXP
ISO
alpha-Tocopherol inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of IL6 protein]
alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:15630180 PMID:24296301 PMID:32134168 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of JUN protein]
alpha-Tocopherol results in increased expression of JUN mRNA; alpha-Tocopherol results in increased expression of JUN protein
CTD PMID:14645110 PMID:19000923 PMID:20025956 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein] CTD PMID:12531891 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G LCAT lecithin-cholesterol acyltransferase multiple interactions ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased activity of LCAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:19595682 PMID:21535577 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase multiple interactions EXP alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LCK protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LCK protein] CTD PMID:14572611 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,239...32,286,165
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:21322096 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
JBrowse link
G LDHB lactate dehydrogenase B multiple interactions ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:21322096 NCBI chr12:21,635,342...21,657,971
Ensembl chr12:21,635,342...21,757,857
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LYN protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LYN protein] CTD PMID:14572611 NCBI chr 8:55,876,041...56,014,169
Ensembl chr 8:55,879,835...56,014,169
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
affects activity
EXP
ISO
alpha-Tocopherol inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK1 protein]
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK1 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of MAPK1 protein]
[alpha-Tocopherol affects the activity of MAPK1 protein] which results in decreased susceptibility to Potassium Dichromate
CTD PMID:17011908 PMID:19766176 PMID:30776390 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein] CTD PMID:12684028 PMID:14645110 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
affects activity
EXP
ISO
alpha-Tocopherol inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK3 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK3 protein]
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of MAPK3 protein]
[alpha-Tocopherol affects the activity of MAPK3 protein] which results in decreased susceptibility to Potassium Dichromate
CTD PMID:14645110 PMID:17011908 PMID:19766176 PMID:30776390 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
EXP alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein] CTD PMID:12684028 PMID:14645110 PMID:20686688 NCBI chr10:48,306,673...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
EXP alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein]
CTD PMID:20686688 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MB myoglobin multiple interactions ISO alpha-Tocopherol inhibits the reaction [MB modified form results in decreased secretion of very low density lipoprotein triglyceride] CTD PMID:17478120 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
JBrowse link
G MBP myelin basic protein multiple interactions EXP alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased expression of MBP protein] CTD PMID:14645110 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683
JBrowse link
G MGAT3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase increases expression ISO alpha-Tocopherol results in increased expression of MGAT3 mRNA CTD PMID:16908007 NCBI chr22:39,457,012...39,492,194
Ensembl chr22:39,457,012...39,492,194
JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G MPO myeloperoxidase multiple interactions ISO [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA] CTD PMID:24333275 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions ISO alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of MYC protein] CTD PMID:16005924 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NEFH neurofilament heavy increases expression ISO alpha-Tocopherol results in increased expression of NEFH protein modified form CTD PMID:18942769 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein]; [alpha-Tocopherol co-treated with Hydrogen Peroxide] affects the localization of NFE2L2 protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of NFE2L2 protein] CTD PMID:22389237 PMID:31412289 PMID:32134168 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
increases activity
ISO
EXP
alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of NFKB1 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of [NFKB1 protein binds to RELA protein]]
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]
alpha-Tocopherol results in increased activity of NFKB1 protein
CTD PMID:15025948 PMID:16135673 PMID:17936189 PMID:19083475 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein]; alpha-Tocopherol inhibits the reaction [DCD protein results in increased phosphorylation of NFKBIA protein]
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]
alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased phosphorylation of NFKBIA protein]
CTD PMID:16135673 PMID:17532611 PMID:25551565 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased expression of NOS2 protein]
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased expression of NOS2 mRNA]
CTD PMID:17936189 PMID:19135433 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 increases expression EXP alpha-Tocopherol results in increased expression of NOS3 mRNA; alpha-Tocopherol results in increased expression of NOS3 protein CTD PMID:16949522 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP alpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA] CTD PMID:17936189 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,485
JBrowse link
G OGDH oxoglutarate dehydrogenase multiple interactions ISO alpha-Tocopherol inhibits the reaction [sodium arsenite results in decreased activity of OGDH protein] CTD PMID:12915223 NCBI chr 7:44,606,572...44,709,066
Ensembl chr 7:44,606,572...44,709,066
JBrowse link
G ORM1 orosomucoid 1 increases expression ISO alpha-Tocopherol results in increased expression of ORM1 mRNA; alpha-Tocopherol results in increased expression of ORM1 protein CTD PMID:19000923 PMID:20025956 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,056...114,326,475
JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions EXP alpha-Tocopherol inhibits the reaction [Rotenone affects the localization of PARK7 protein] CTD PMID:16439141 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP
ISO
alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]
alpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]
CTD PMID:14645110 PMID:24448832 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
G PAWR pro-apoptotic WT1 regulator multiple interactions ISO alpha-Tocopherol inhibits the reaction [Nerve Growth Factors deficiency results in increased expression of PAWR mRNA]; alpha-Tocopherol inhibits the reaction [Nerve Growth Factors deficiency results in increased expression of PAWR protein] CTD PMID:10428045 NCBI chr12:79,584,879...79,691,097
Ensembl chr12:79,574,979...79,690,964
JBrowse link
G PAX3 paired box 3 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of PAX3 mRNA]
alpha-Tocopherol results in increased expression of PAX3 mRNA
CTD PMID:12739027 NCBI chr 2:222,199,887...222,298,998
Ensembl chr 2:222,199,888...222,298,996
Ensembl chr 2:222,199,888...222,298,996
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO alpha-Tocopherol results in decreased expression of PCK1 mRNA CTD PMID:11597575 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PDGFRB platelet derived growth factor receptor beta multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PGK1 phosphoglycerate kinase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] CTD PMID:18603805 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295
JBrowse link
G PLG plasminogen multiple interactions EXP alpha-Tocopherol inhibits the reaction [Arsenic promotes the reaction [Humic Substances results in decreased activity of PLG protein]]; alpha-Tocopherol inhibits the reaction [Humic Substances results in decreased activity of PLG protein] CTD PMID:11419606 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G PLTP phospholipid transfer protein decreases abundance ISO PLTP mutant form results in decreased abundance of alpha-Tocopherol CTD PMID:16675720 NCBI chr20:45,898,620...45,912,155
Ensembl chr20:45,898,621...45,912,155
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of PPARA mRNA]
alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of PPARA mRNA]
alpha-Tocopherol results in increased expression of PPARA mRNA
CTD PMID:17936189 PMID:29065513 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
multiple interactions
increases activity
EXP
ISO
alpha-Tocopherol results in increased expression of PPARG mRNA; alpha-Tocopherol results in increased expression of PPARG protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein]
alpha-Tocopherol results in increased activity of PPARG protein
CTD PMID:11752099 PMID:14521714 PMID:19083475 PMID:22389237 PMID:28062356 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPIA peptidylprolyl isomerase A increases expression ISO alpha-Tocopherol results in increased expression of PPIA mRNA CTD PMID:16908007 NCBI chr 7:44,795,960...44,803,117
Ensembl chr 7:44,796,680...44,824,564
JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein] CTD PMID:17532611 NCBI chr14:52,707,163...52,728,590
Ensembl chr14:52,707,178...52,728,590
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
EXP
ISO
alpha-Tocopherol metabolite results in decreased activity of PTGS2 protein; alpha-Tocopherol results in decreased activity of PTGS2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein]
CTD PMID:15225597 PMID:22389237 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit affects localization
multiple interactions
EXP
ISO
alpha-Tocopherol affects the localization of RELA protein
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]
alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of RELA protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:15025948 PMID:16135673 PMID:16882165 PMID:17936189 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RPS6 ribosomal protein S6 multiple interactions EXP alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of RPS6 protein] CTD PMID:22343715 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
JBrowse link
G RXRA retinoid X receptor alpha multiple interactions EXP [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA protein; [Tretinoin co-treated with alpha-Tocopherol] results in decreased phosphorylation of RXRA protein CTD PMID:15225641 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
JBrowse link
G SELE selectin E multiple interactions EXP [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of SELE protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:12566129 PMID:25551565 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
JBrowse link
G SLC7A11 solute carrier family 7 member 11 multiple interactions EXP [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 mRNA; [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 protein CTD PMID:24530478 NCBI chr 4:138,164,097...138,242,349
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SMAD4 SMAD family member 4 multiple interactions EXP SMAD4 results in decreased susceptibility to [Fluorouracil co-treated with alpha-Tocopherol] CTD PMID:20562578 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SNCA synuclein alpha multiple interactions EXP alpha-Tocopherol inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:16439141 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases expression
ISO
EXP
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of SOD1 protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein]
alpha-Tocopherol results in increased expression of SOD1 mRNA; alpha-Tocopherol results in increased expression of SOD1 protein
CTD PMID:19083475 PMID:20194575 PMID:21344382 PMID:22732938 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 decreases expression
increases expression
multiple interactions
ISO alpha-Tocopherol results in decreased expression of SOD2 protein
alpha-Tocopherol results in increased expression of SOD2 mRNA; alpha-Tocopherol results in increased expression of SOD2 protein
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased expression of and results in increased activity of SOD2 protein]
CTD PMID:16135673 PMID:18942769 PMID:20194575 PMID:22732938 PMID:23859036 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 decreases expression ISO alpha-Tocopherol deficiency results in decreased expression of SRSF2 protein CTD PMID:15247049 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,374
Ensembl chr17:76,734,115...76,737,374
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of STAR mRNA] CTD PMID:32134168 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression ISO alpha-Tocopherol results in increased expression of STAT3 mRNA CTD PMID:16908007 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
JBrowse link
G TERT telomerase reverse transcriptase multiple interactions EXP alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased activity of TERT protein] CTD PMID:20112180 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TGFA transforming growth factor alpha decreases response to substance ISO alpha-Tocopherol results in decreased susceptibility to TGFA protein CTD PMID:7593635 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions
decreases expression
ISO alpha-Tocopherol inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]
alpha-Tocopherol results in decreased expression of TGFB1 mRNA
CTD PMID:9608545 PMID:14732287 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; alpha-Tocopherol inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:15790535 PMID:25891525 NCBI chr11:2,163,929...2,174,081
Ensembl chr11:2,163,929...2,171,877
Ensembl chr11:2,163,929...2,171,877
JBrowse link
G TNF tumor necrosis factor multiple interactions
affects expression
decreases response to substance
decreases expression
EXP
ISO
[alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of TNF protein; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; alpha-Tocopherol promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased secretion of TNF protein]
alpha-Tocopherol affects the expression of TNF protein
alpha-Tocopherol results in decreased susceptibility to TNF protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of TNF mRNA]
alpha-Tocopherol results in decreased expression of TNF protein
CTD PMID:10588948 PMID:11805214 PMID:12195823 PMID:15025948 PMID:15630180 PMID:16135673 PMID:16750838 PMID:18191645 PMID:19135038 PMID:19135433 PMID:19735175 PMID:23042730 PMID:25551565 PMID:26332274 PMID:30776390 PMID:31712109 PMID:32134168 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b increases expression
multiple interactions
EXP alpha-Tocopherol analog results in increased expression of TNFRSF10B mRNA; alpha-Tocopherol analog results in increased expression of TNFRSF10B protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased expression of TNFRSF10B protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased expression of TNFRSF10B protein]; TNFRSF10B mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]
CTD PMID:20686688 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 mRNA]; alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 protein] CTD PMID:12126965 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TXN thioredoxin multiple interactions ISO [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of TXN1 protein] CTD PMID:21344382 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of VCAM1 protein]; alpha-Tocopherol inhibits the reaction [Vehicle Emissions results in increased expression of VCAM1 protein] CTD PMID:12566129 PMID:22313677 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G XBP1 X-box binding protein 1 increases expression EXP alpha-Tocopherol analog results in increased expression of XBP1 mRNA CTD PMID:20686688 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
G XRCC6 X-ray repair cross complementing 6 multiple interactions ISO alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] CTD PMID:26332274 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048
Ensembl chr22:41,621,163...41,664,048
JBrowse link
alpha-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression EXP tocotrienol, alpha results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression
multiple interactions
EXP tocotrienol, alpha results in increased expression of CYP3A4
tocotrienol, alpha inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; tocotrienol, alpha inhibits the reaction [CYP3A4 protein results in increased oxidation of Lithocholic Acid]
CTD PMID:15269186 PMID:31102695 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 multiple interactions
affects response to substance
EXP tocotrienol, alpha inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; tocotrienol, alpha inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]
CYP3A5 gene polymorphism affects the susceptibility to tocotrienol, alpha
CTD PMID:31102695 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions EXP GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha] CTD PMID:15668500 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G NCOR1 nuclear receptor corepressor 1 multiple interactions EXP tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr17:16,029,157...16,216,475
Ensembl chr17:16,029,157...16,218,185
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP tocotrienol, alpha binds to and results in increased activity of NR1I2 protein; tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,485
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP tocotrienol, alpha results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
beta-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions ISO
EXP
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]
beta-Tocopherol affects the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; beta-Tocopherol affects the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]
CTD PMID:12450566 PMID:22389237 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein] CTD PMID:22389237 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein] CTD PMID:22389237 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein] CTD PMID:22389237 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein] CTD PMID:22389237 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
beta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression EXP tocotrienol, beta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression EXP tocotrienol, beta results in increased expression of CYP3A4 CTD PMID:15269186 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G NCOR1 nuclear receptor corepressor 1 multiple interactions EXP tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr17:16,029,157...16,216,475
Ensembl chr17:16,029,157...16,218,185
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP tocotrienol, beta binds to and results in increased activity of NR1I2 protein; tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,485
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP tocotrienol, beta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
delta-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein] CTD PMID:22389237 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 multiple interactions EXP [Tretinoin co-treated with delta-tocopherol] results in increased expression of CRABP2 mRNA CTD PMID:15225641 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein] CTD PMID:22389237 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein] CTD PMID:22389237 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein] CTD PMID:22389237 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein] CTD PMID:22389237 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
delta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression EXP tocotrienol, delta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of ABCC1 mRNA]
tocotrienol, delta results in increased expression of ABCC1 mRNA
CTD PMID:22185406 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,577...16,143,074
Ensembl chr16:15,949,577...16,143,074
JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 decreases expression ISO tocotrienol, delta results in decreased expression of ABCD2 mRNA CTD PMID:22185406 NCBI chr12:39,530,965...39,651,333
Ensembl chr12:39,550,033...39,619,803
JBrowse link
G ACTL6B actin like 6B increases expression ISO tocotrienol, delta results in increased expression of ACTL6B mRNA CTD PMID:22185406 NCBI chr 7:100,643,097...100,656,448
Ensembl chr 7:100,643,097...100,656,448
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
increases expression
ISO tocotrienol, delta promotes the reaction [Lipopolysaccharides results in increased expression of ATP2A2 mRNA]
tocotrienol, delta results in increased expression of ATP2A2 mRNA
CTD PMID:22185406 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G CCND1 cyclin D1 decreases expression EXP tocotrienol, delta results in decreased expression of CCND1 protein CTD PMID:21453743 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND2 cyclin D2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CCND2 mRNA]
tocotrienol, delta results in increased expression of CCND2 mRNA
CTD PMID:22185406 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
Ensembl chr12:4,269,771...4,305,353
JBrowse link
G CD40 CD40 molecule multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA]
tocotrienol, delta results in increased expression of CD40 mRNA
CTD PMID:22185406 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CD69 CD69 molecule multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 mRNA]
tocotrienol, delta results in increased expression of CD69 mRNA
CTD PMID:22185406 NCBI chr12:9,752,486...9,760,901
Ensembl chr12:9,752,486...9,760,901
JBrowse link
G COX7B2 cytochrome c oxidase subunit 7B2 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of COX7B2 mRNA]
tocotrienol, delta results in decreased expression of COX7B2 mRNA
CTD PMID:22185406 NCBI chr 4:46,734,827...46,909,266
Ensembl chr 4:46,734,827...46,909,245
JBrowse link
G CRP C-reactive protein multiple interactions EXP [resveratrol co-treated with pterostilbene co-treated with Quercetin co-treated with tocotrienol, delta co-treated with Niacin] results in decreased expression of CRP protein CTD PMID:24319627 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CTNNB1 catenin beta 1 decreases expression EXP tocotrienol, delta results in decreased expression of CTNNB1 protein CTD PMID:21453743 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression
multiple interactions
EXP tocotrienol, delta results in increased expression of CYP3A4
tocotrienol, delta inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; tocotrienol, delta inhibits the reaction [CYP3A4 protein results in increased oxidation of Lithocholic Acid]
CTD PMID:15269186 PMID:31102695 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 affects response to substance
multiple interactions
EXP CYP3A5 gene polymorphism affects the susceptibility to tocotrienol, delta
tocotrienol, delta inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; tocotrienol, delta inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]
CTD PMID:31102695 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
JBrowse link
G GIMAP1 GTPase, IMAP family member 1 multiple interactions
decreases expression
ISO tocotrienol, delta promotes the reaction [Lipopolysaccharides results in decreased expression of GIMAP1 mRNA]
tocotrienol, delta results in decreased expression of GIMAP1 mRNA
CTD PMID:22185406 NCBI chr 7:150,716,613...150,724,284
Ensembl chr 7:150,716,606...150,724,284
JBrowse link
G ICAM1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of ICAM1 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]
CTD PMID:22185406 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNB1 interferon beta 1 multiple interactions ISO tocotrienol, delta inhibits the reaction [[IFNB1 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:22185406 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
JBrowse link
G IFNG interferon gamma multiple interactions ISO tocotrienol, delta inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:22185406 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNGR1 interferon gamma receptor 1 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of IFNGR1 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of IFNGR1 mRNA]
CTD PMID:22185406 NCBI chr 6:137,197,484...137,220,351
Ensembl chr 6:137,197,484...137,219,449
Ensembl chr 6:137,197,484...137,219,449
JBrowse link
G IL12B interleukin 12B decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of IL12B mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
CTD PMID:22185406 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,487
JBrowse link
G IL1A interleukin 1 alpha increases expression ISO tocotrienol, delta results in increased expression of IL1A mRNA CTD PMID:22185406 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
tocotrienol, delta results in increased expression of IL1B mRNA
CTD PMID:22185406 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist increases expression
multiple interactions
ISO tocotrienol, delta results in increased expression of IL1RN mRNA
tocotrienol, delta promotes the reaction [Lipopolysaccharides results in increased expression of IL1RN mRNA]
CTD PMID:22185406 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
ISO tocotrienol, delta results in increased expression of IL6 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:22185406 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP tocotrienol, delta results in decreased expression of JUN protein CTD PMID:21453743 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G MMP7 matrix metallopeptidase 7 decreases expression EXP tocotrienol, delta results in decreased expression of MMP7 protein CTD PMID:21453743 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G NCOR1 nuclear receptor corepressor 1 multiple interactions EXP tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr17:16,029,157...16,216,475
Ensembl chr17:16,029,157...16,218,185
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Lipopolysaccharides inhibits the reaction [tocotrienol, delta results in increased expression of NOS2]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:21356098 PMID:22185406 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP tocotrienol, delta binds to and results in increased activity of NR1I2 protein; tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,485
JBrowse link
G PHKA2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PHKA2 mRNA]
tocotrienol, delta results in increased expression of PHKA2 mRNA
CTD PMID:22185406 NCBI chr  X:18,892,298...18,984,114
Ensembl chr  X:18,892,298...18,984,114
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 decreases expression ISO tocotrienol, delta results in decreased expression of PSMB2 mRNA CTD PMID:22185406 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PTBP2 polypyrimidine tract binding protein 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA]
tocotrienol, delta results in increased expression of PTBP2 mRNA
CTD PMID:22185406 NCBI chr 1:96,721,766...96,823,739
Ensembl chr 1:96,721,665...96,823,738
JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of RASGRP1 mRNA]
tocotrienol, delta results in increased expression of RASGRP1 mRNA
CTD PMID:22185406 NCBI chr15:38,488,097...38,564,814
Ensembl chr15:38,488,103...38,565,575
JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of RASGRP3 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of RASGRP3 mRNA]
CTD PMID:22185406 NCBI chr 2:33,436,348...33,564,731
Ensembl chr 2:33,436,324...33,564,750
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]
tocotrienol, delta results in decreased expression of SOCS3 mRNA
CTD PMID:22185406 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
ISO Lipopolysaccharides inhibits the reaction [tocotrienol, delta results in increased expression of TNF]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
tocotrienol, delta results in decreased expression of TNF mRNA
CTD PMID:21356098 PMID:22185406 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNP1 transition protein 1 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of TNP1 mRNA]
tocotrienol, delta results in decreased expression of TNP1 mRNA
CTD PMID:22185406 NCBI chr 2:216,859,458...216,860,064
Ensembl chr 2:216,859,458...216,860,064
JBrowse link
G TRAF1 TNF receptor associated factor 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of TRAF1 mRNA]
tocotrienol, delta results in increased expression of TRAF1 mRNA
CTD PMID:22185406 NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173
JBrowse link
G UBE2D2 ubiquitin conjugating enzyme E2 D2 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA]
tocotrienol, delta results in decreased expression of UBE2D2A mRNA
CTD PMID:22185406 NCBI chr 5:139,561,286...139,628,434
Ensembl chr 5:139,526,431...139,628,434
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP tocotrienol, delta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]
tocotrienol, delta results in decreased expression of VCAM1 mRNA
CTD PMID:22185406 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G WNT1 Wnt family member 1 decreases expression EXP tocotrienol, delta results in decreased expression of WNT1 protein CTD PMID:21453743 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620
JBrowse link
gamma-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
EXP Tocopherols results in decreased activity of ABCC1 protein
Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]
CTD PMID:15617835 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,577...16,143,074
Ensembl chr16:15,949,577...16,143,074
JBrowse link
G ALB albumin multiple interactions ISO gamma-Tocopherol inhibits the reaction [ALB protein results in increased expression of MUC5AC mRNA] CTD PMID:19389874 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G APP amyloid beta precursor protein decreases abundance
multiple interactions
ISO APP protein modified form results in decreased abundance of Tocopherols
resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Tocopherols]
CTD PMID:25654502 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G AR androgen receptor decreases activity
decreases expression
EXP Tocopherols results in decreased activity of AR protein
[Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of AR mRNA; Tocopherols results in decreased expression of AR protein
CTD PMID:12032296 PMID:16302272 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARF3 ADP ribosylation factor 3 increases expression ISO Tocopherols results in increased expression of ARF3 mRNA CTD PMID:17654050 NCBI chr12:48,930,252...48,957,526
Ensembl chr12:48,935,723...48,957,487
JBrowse link
G ASPM assembly factor for spindle microtubules increases expression ISO Tocopherols results in increased expression of ASPM mRNA CTD PMID:17056531 NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,127...197,146,694
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Tocopherols results in increased expression of ATP1A2 mRNA CTD PMID:17654050 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Tocopherols results in increased expression of ATP1B2 mRNA CTD PMID:17654050 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G AURKA aurora kinase A increases expression ISO Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 NCBI chr20:56,369,390...56,392,308
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases response to substance
increases expression
multiple interactions
EXP BAX protein results in increased susceptibility to Tocopherols
gamma-Tocopherol results in increased expression of BAX mRNA
[Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA
CTD PMID:16001965 PMID:31587439 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions
decreases expression
decreases response to substance
ISO
EXP
Tocopherols results in increased expression of BCL2 mRNA; Tocopherols results in increased expression of BCL2 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA
gamma-Tocopherol results in decreased expression of BCL2 mRNA
BCL2 protein results in decreased susceptibility to Tocopherols
CTD PMID:8970189 PMID:16001965 PMID:31587439 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases response to substance EXP BCL2L1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression ISO Tocopherols results in increased expression of BIRC5 mRNA CTD PMID:17056531 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma increases expression ISO Tocopherols results in increased expression of CAMK2G mRNA CTD PMID:17654050 NCBI chr10:73,812,501...73,874,582
Ensembl chr10:73,812,501...73,874,591
JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions
EXP
ISO
gamma-Tocopherol results in increased activity of CASP3 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]
thermozymocidin inhibits the reaction [gamma-Tocopherol results in increased activity of CASP3 protein]
CTD PMID:15596715 PMID:22389237 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 increases activity EXP gamma-Tocopherol results in increased activity of CASP9 protein CTD PMID:15596715 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase increases expression ISO gamma-Tocopherol results in increased expression of CAT protein CTD PMID:19115203 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCNB2 cyclin B2 increases expression ISO Tocopherols results in increased expression of CCNB2 mRNA CTD PMID:17056531 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions
EXP gamma-Tocopherol results in decreased expression of CCND1 mRNA; gamma-Tocopherol results in decreased expression of CCND1 protein; Tocopherols results in decreased expression of CCND1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA
CTD PMID:12368234 PMID:12504091 PMID:31587439 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND3 cyclin D3 decreases expression EXP Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCNE1 cyclin E1 decreases expression
multiple interactions
EXP gamma-Tocopherol results in decreased expression of CCNE1 mRNA; gamma-Tocopherol results in decreased expression of CCNE1 protein; Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA
CTD PMID:12368234 PMID:12504091 PMID:31587439 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CDC6 cell division cycle 6 increases expression ISO Tocopherols results in increased expression of CDC6 mRNA CTD PMID:17056531 NCBI chr17:40,287,878...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CDK1 cyclin dependent kinase 1 increases expression ISO Tocopherols results in increased expression of CDK1 mRNA CTD PMID:17056531 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK4 cyclin dependent kinase 4 multiple interactions EXP Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein CTD PMID:12504091 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 increases expression ISO Tocopherols results in increased expression of CDK5R1 mRNA CTD PMID:17654050 NCBI chr17:32,485,028...32,491,256
Ensembl chr17:32,486,993...32,491,253
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A decreases expression EXP gamma-Tocopherol results in decreased expression of CDKN1A protein CTD PMID:12368234 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression EXP gamma-Tocopherol results in decreased expression of CDKN1B protein CTD PMID:12368234 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,715,058...12,722,369
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A decreases expression EXP gamma-Tocopherol results in decreased expression of CDKN2A protein CTD PMID:12368234 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CLEC4E C-type lectin domain family 4 member E increases expression ISO Tocopherols results in increased expression of CLEC4E mRNA CTD PMID:17056531 NCBI chr12:8,533,305...8,541,327
Ensembl chr12:8,533,305...8,540,905
JBrowse link
G CPLX1 complexin 1 increases expression ISO Tocopherols results in increased expression of CPLX1 mRNA CTD PMID:17654050 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129
JBrowse link
G CPLX2 complexin 2 increases expression ISO Tocopherols results in increased expression of CPLX2 mRNA CTD PMID:17654050 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 multiple interactions EXP [Tretinoin co-treated with gamma-Tocopherol] results in increased expression of CRABP2 mRNA CTD PMID:15225641 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CRP C-reactive protein multiple interactions EXP [alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of CRP protein CTD PMID:18191645 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF1R colony stimulating factor 1 receptor increases expression ISO Tocopherols results in increased expression of CSF1R mRNA CTD PMID:17056531 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSRP2 cysteine and glycine rich protein 2 increases expression ISO Tocopherols results in increased expression of CSRP2 mRNA CTD PMID:17056531 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G DNAJC5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Tocopherols results in increased expression of DNAJC5 mRNA CTD PMID:17654050 NCBI chr20:63,895,126...63,936,026
Ensembl chr20:63,895,126...63,936,031
JBrowse link
G E2F1 E2F transcription factor 1 increases expression EXP Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G EGR1 early growth response 1 decreases activity EXP Tocopherols results in decreased activity of EGR1 protein CTD PMID:15878867 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia increases expression ISO Tocopherols results in increased expression of FCER1A mRNA CTD PMID:17056531 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FES FES proto-oncogene, tyrosine kinase increases expression ISO Tocopherols results in increased expression of FES mRNA CTD PMID:17056531 NCBI chr15:90,884,421...90,895,776
Ensembl chr15:90,883,695...90,895,776
JBrowse link
G FGF1 fibroblast growth factor 1 decreases expression EXP Tocopherols results in decreased expression of FGF1 mRNA CTD PMID:15878867 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGF2 fibroblast growth factor 2 decreases expression EXP Tocopherols results in decreased expression of FGF2 mRNA CTD PMID:15878867 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 decreases expression EXP Tocopherols results in decreased expression of FGFR1 mRNA CTD PMID:15144885 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FKBP9 FKBP prolyl isomerase 9 increases expression ISO Tocopherols results in increased expression of FKBP9 mRNA CTD PMID:17056531 NCBI chr 7:32,957,427...33,006,928
Ensembl chr 7:32,957,404...33,006,930
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of FOS mRNA; Tocopherols results in increased expression of FOS protein CTD PMID:8970189 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Tocopherols results in increased expression of GRIA2 mRNA CTD PMID:17654050 NCBI chr 4:157,220,120...157,370,583
Ensembl chr 4:157,204,182...157,366,075
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 NCBI chr 9:137,139,092...137,168,759
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GSTM1 glutathione S-transferase mu 1 increases expression
multiple interactions
ISO gamma-Tocopherol results in increased expression of GSTM1 mRNA; gamma-Tocopherol results in increased expression of GSTM1 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]
CTD PMID:19115203 PMID:22389237 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTO1 glutathione S-transferase omega 1 decreases activity EXP Tocopherols results in decreased activity of GSTO1 protein CTD PMID:16781109 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link
G HASPIN histone H3 associated protein kinase increases expression ISO Tocopherols results in increased expression of HASPIN mRNA CTD PMID:17056531 NCBI chr17:3,723,903...3,726,699
Ensembl chr17:3,723,903...3,726,699
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions
ISO gamma-Tocopherol results in increased expression of HMOX1 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein]
CTD PMID:19115203 PMID:22389237 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of JUN mRNA; Tocopherols results in increased expression of JUN protein CTD PMID:8970189 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KIF20A kinesin family member 20A increases expression ISO Tocopherols results in increased expression of KIF20A mRNA CTD PMID:17056531 NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
JBrowse link
G KIF4A kinesin family member 4A increases expression ISO Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 NCBI chr  X:70,290,104...70,420,886
Ensembl chr  X:70,290,104...70,420,886
JBrowse link
G KLK3 kallikrein related peptidase 3 multiple interactions
decreases expression
EXP Tocopherols inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; Tocopherols inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]
[Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of KLK3 mRNA; Tocopherols results in decreased expression of KLK3 protein
CTD PMID:12032296 PMID:16302272 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases response to substance EXP MCL1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,574,551...150,579,738
Ensembl chr 1:150,574,551...150,579,738
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO gamma-Tocopherol inhibits the reaction [ALB protein results in increased expression of MUC5AC mRNA] CTD PMID:19389874 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression
decreases activity
ISO Tocopherols results in decreased expression of MYC mRNA
Tocopherols results in decreased activity of MYC protein
CTD PMID:8970189 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAPB NSF attachment protein beta increases expression ISO Tocopherols results in increased expression of NAPB mRNA CTD PMID:17654050 NCBI chr20:23,374,522...23,421,498
Ensembl chr20:23,374,519...23,421,519
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 increases expression
multiple interactions
ISO gamma-Tocopherol results in increased expression of NFE2L2 mRNA; gamma-Tocopherol results in increased expression of NFE2L2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein]
CTD PMID:19115203 PMID:22389237 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Tocopherols results in increased expression of NSF mRNA CTD PMID:17654050 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,464
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions
decreases expression
ISO [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein]
Tocopherols results in decreased expression of PCNA
CTD PMID:17927505 PMID:22389237 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
multiple interactions
EXP
ISO
gamma-Tocopherol results in increased expression of PPARG mRNA; gamma-Tocopherol results in increased expression of PPARG protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein]
CTD PMID:14521714 PMID:22389237 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha increases expression ISO Tocopherols results in increased expression of PPP3CA mRNA CTD PMID:17654050 NCBI chr 4:101,023,418...101,348,295
Ensembl chr 4:101,023,409...101,348,278
JBrowse link
G PRTN3 proteinase 3 increases expression ISO Tocopherols results in increased expression of PRTN3 mRNA CTD PMID:17056531 NCBI chr19:840,965...848,175
Ensembl chr19:840,999...848,175
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
EXP
ISO
gamma-Tocopherol results in decreased activity of PTGS2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein]
CTD PMID:15225597 PMID:22389237 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O increases expression ISO Tocopherols results in increased expression of PTPRO mRNA CTD PMID:17056531 NCBI chr12:15,322,334...15,598,331
Ensembl chr12:15,322,508...15,598,331
Ensembl chr12:15,322,508...15,598,331
JBrowse link
G RAB11B RAB11B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB11B mRNA CTD PMID:17654050 NCBI chr19:8,390,360...8,404,434
Ensembl chr19:8,389,981...8,404,434
JBrowse link
G RAB3A RAB3A, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB3A mRNA CTD PMID:17654050 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042
JBrowse link
G RAB6B RAB6B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB6B mRNA CTD PMID:17654050 NCBI chr 3:133,824,235...133,895,882
Ensembl chr 3:133,824,235...133,895,882
JBrowse link
G RB1 RB transcriptional corepressor 1 decreases phosphorylation EXP Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 increases expression ISO Tocopherols results in increased expression of RRM1 mRNA CTD PMID:17056531 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
JBrowse link
G SNCA synuclein alpha increases expression ISO Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SNCB synuclein beta increases expression ISO Tocopherols results in increased expression of SNCB mRNA CTD PMID:17654050 NCBI chr 5:176,620,082...176,630,556
Ensembl chr 5:176,620,082...176,630,556
JBrowse link
G SOD1 superoxide dismutase 1 increases expression ISO gamma-Tocopherol results in increased expression of SOD1 protein CTD PMID:19115203 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G STX1A syntaxin 1A increases expression ISO Tocopherols results in increased expression of STX1A mRNA CTD PMID:17654050 NCBI chr 7:73,699,210...73,719,673
Ensembl chr 7:73,699,206...73,719,672
JBrowse link
G STXBP1 syntaxin binding protein 1 increases expression ISO Tocopherols results in increased expression of STXBP1 mRNA CTD PMID:17654050 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G SV2A synaptic vesicle glycoprotein 2A increases expression ISO Tocopherols results in increased expression of SV2A mRNA CTD PMID:17654050 NCBI chr 1:149,903,318...149,917,844
Ensembl chr 1:149,903,318...149,917,844
JBrowse link
G SYN1 synapsin I increases expression ISO Tocopherols results in increased expression of SYN1 mRNA CTD PMID:17654050 NCBI chr  X:47,571,901...47,619,857
Ensembl chr  X:47,571,901...47,619,857
JBrowse link
G SYN2 synapsin II increases expression ISO Tocopherols results in increased expression of SYN2 mRNA CTD PMID:17654050 NCBI chr 3:12,004,366...12,192,032
Ensembl chr 3:12,004,388...12,192,032
JBrowse link
G SYNGR1 synaptogyrin 1 increases expression ISO Tocopherols results in increased expression of SYNGR1 mRNA CTD PMID:17654050 NCBI chr22:39,349,991...39,385,575
Ensembl chr22:39,349,925...39,385,575
JBrowse link
G SYP synaptophysin increases expression ISO Tocopherols results in increased expression of SYP mRNA CTD PMID:17654050 NCBI chr  X:49,187,815...49,200,193
Ensembl chr  X:49,187,815...49,200,199
Ensembl chr  X:49,187,815...49,200,199
JBrowse link
G SYT11 synaptotagmin 11 increases expression ISO Tocopherols results in increased expression of SYT11 mRNA CTD PMID:17654050 NCBI chr 1:155,859,502...155,885,199
Ensembl chr 1:155,859,567...155,885,199
JBrowse link
G SYT13 synaptotagmin 13 increases expression ISO Tocopherols results in increased expression of SYT13 mRNA CTD PMID:17654050 NCBI chr11:45,240,302...45,286,341
Ensembl chr11:45,240,302...45,286,341
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO
[alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of TNF protein
Tocopherols inhibits the reaction [TNF protein results in decreased export of Potassium]
CTD PMID:17337591 PMID:18191645 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP2 TNF alpha induced protein 2 increases expression ISO Tocopherols results in increased expression of TNFAIP2 mRNA CTD PMID:17056531 NCBI chr14:103,121,175...103,137,439
Ensembl chr14:103,121,476...103,137,439
Ensembl chr14:103,121,476...103,137,439
JBrowse link
G TP53 tumor protein p53 increases activity EXP Tocopherols results in increased activity of TP53 protein CTD PMID:15883045 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TTC3 tetratricopeptide repeat domain 3 increases expression ISO Tocopherols results in increased expression of TTC3 mRNA CTD PMID:17654050 NCBI chr21:37,073,235...37,203,118
Ensembl chr21:37,073,226...37,203,112
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions
ISO gamma-Tocopherol results in increased expression of UGT1A1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA]
CTD PMID:19115203 PMID:22389237 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G VAMP1 vesicle associated membrane protein 1 increases expression ISO Tocopherols results in increased expression of VAMP1 mRNA CTD PMID:17654050 NCBI chr12:6,462,237...6,470,677
Ensembl chr12:6,462,237...6,470,987
Ensembl chr12:6,462,237...6,470,987
JBrowse link
G VAMP2 vesicle associated membrane protein 2 increases expression ISO Tocopherols results in increased expression of VAMP2 mRNA CTD PMID:17654050 NCBI chr17:8,159,147...8,162,948
Ensembl chr17:8,159,149...8,163,546
JBrowse link
G VDR vitamin D receptor increases expression EXP Tocopherols results in increased expression of VDR mRNA CTD PMID:12032296 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
EXP Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]
Tocopherols results in decreased activity of ABCC1 protein
CTD PMID:15617835 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,577...16,143,074
Ensembl chr16:15,949,577...16,143,074
JBrowse link
G APP amyloid beta precursor protein multiple interactions
decreases abundance
ISO resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Tocopherols] CTD PMID:25654502 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G AR androgen receptor decreases activity
decreases expression
EXP Tocopherols results in decreased activity of AR protein
[Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of AR mRNA; Tocopherols results in decreased expression of AR protein
CTD PMID:12032296 PMID:16302272 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARF3 ADP ribosylation factor 3 increases expression ISO Tocopherols results in increased expression of ARF3 mRNA CTD PMID:17654050 NCBI chr12:48,930,252...48,957,526
Ensembl chr12:48,935,723...48,957,487
JBrowse link
G ASPM assembly factor for spindle microtubules increases expression ISO Tocopherols results in increased expression of ASPM mRNA CTD PMID:17056531 NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,127...197,146,694
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Tocopherols results in increased expression of ATP1A2 mRNA CTD PMID:17654050 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Tocopherols results in increased expression of ATP1B2 mRNA CTD PMID:17654050 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G AURKA aurora kinase A increases expression ISO Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 NCBI chr20:56,369,390...56,392,308
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases response to substance EXP BAX protein results in increased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases response to substance
increases expression
EXP
ISO
BCL2 protein results in decreased susceptibility to Tocopherols
Tocopherols results in increased expression of BCL2 mRNA; Tocopherols results in increased expression of BCL2 protein
CTD PMID:8970189 PMID:16001965 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases response to substance EXP BCL2L1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression ISO Tocopherols results in increased expression of BIRC5 mRNA CTD PMID:17056531 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma increases expression ISO Tocopherols results in increased expression of CAMK2G mRNA CTD PMID:17654050 NCBI chr10:73,812,501...73,874,582
Ensembl chr10:73,812,501...73,874,591
JBrowse link
G CCNB2 cyclin B2 increases expression ISO Tocopherols results in increased expression of CCNB2 mRNA CTD PMID:17056531 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
JBrowse link
G CCND1 cyclin D1 decreases expression EXP Tocopherols results in decreased expression of CCND1 protein CTD PMID:12504091 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND3 cyclin D3 decreases expression EXP Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCNE1 cyclin E1 decreases expression EXP Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 protein CTD PMID:12504091 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CDC6 cell division cycle 6 increases expression ISO Tocopherols results in increased expression of CDC6 mRNA CTD PMID:17056531 NCBI chr17:40,287,878...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CDK1 cyclin dependent kinase 1 increases expression ISO Tocopherols results in increased expression of CDK1 mRNA CTD PMID:17056531 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK4 cyclin dependent kinase 4 multiple interactions EXP Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein CTD PMID:12504091 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 increases expression ISO Tocopherols results in increased expression of CDK5R1 mRNA CTD PMID:17654050 NCBI chr17:32,485,028...32,491,256
Ensembl chr17:32,486,993...32,491,253
JBrowse link
G CLEC4E C-type lectin domain family 4 member E increases expression ISO Tocopherols results in increased expression of CLEC4E mRNA CTD PMID:17056531 NCBI chr12:8,533,305...8,541,327
Ensembl chr12:8,533,305...8,540,905
JBrowse link
G CPLX1 complexin 1 increases expression ISO Tocopherols results in increased expression of CPLX1 mRNA CTD PMID:17654050 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129
JBrowse link
G CPLX2 complexin 2 increases expression ISO Tocopherols results in increased expression of CPLX2 mRNA CTD PMID:17654050 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
JBrowse link
G CSF1R colony stimulating factor 1 receptor increases expression ISO Tocopherols results in increased expression of CSF1R mRNA CTD PMID:17056531 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSRP2 cysteine and glycine rich protein 2 increases expression ISO Tocopherols results in increased expression of CSRP2 mRNA CTD PMID:17056531 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
JBrowse link
G DNAJC5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Tocopherols results in increased expression of DNAJC5 mRNA CTD PMID:17654050 NCBI chr20:63,895,126...63,936,026
Ensembl chr20:63,895,126...63,936,031
JBrowse link
G E2F1 E2F transcription factor 1 increases expression EXP Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G EGR1 early growth response 1 decreases activity EXP Tocopherols results in decreased activity of EGR1 protein CTD PMID:15878867 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia increases expression ISO Tocopherols results in increased expression of FCER1A mRNA CTD PMID:17056531 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FES FES proto-oncogene, tyrosine kinase increases expression ISO Tocopherols results in increased expression of FES mRNA CTD PMID:17056531 NCBI chr15:90,884,421...90,895,776
Ensembl chr15:90,883,695...90,895,776
JBrowse link
G FGF1 fibroblast growth factor 1 decreases expression EXP Tocopherols results in decreased expression of FGF1 mRNA CTD PMID:15878867 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGF2 fibroblast growth factor 2 decreases expression EXP Tocopherols results in decreased expression of FGF2 mRNA CTD PMID:15878867 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 decreases expression EXP Tocopherols results in decreased expression of FGFR1 mRNA CTD PMID:15144885 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FKBP9 FKBP prolyl isomerase 9 increases expression ISO Tocopherols results in increased expression of FKBP9 mRNA CTD PMID:17056531 NCBI chr 7:32,957,427...33,006,928
Ensembl chr 7:32,957,404...33,006,930
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of FOS mRNA; Tocopherols results in increased expression of FOS protein CTD PMID:8970189 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Tocopherols results in increased expression of GRIA2 mRNA CTD PMID:17654050 NCBI chr 4:157,220,120...157,370,583
Ensembl chr 4:157,204,182...157,366,075
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 NCBI chr 9:137,139,092...137,168,759
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GSTO1 glutathione S-transferase omega 1 decreases activity EXP Tocopherols results in decreased activity of GSTO1 protein CTD PMID:16781109 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link
G HASPIN histone H3 associated protein kinase increases expression ISO Tocopherols results in increased expression of HASPIN mRNA CTD PMID:17056531 NCBI chr17:3,723,903...3,726,699
Ensembl chr17:3,723,903...3,726,699
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of JUN mRNA; Tocopherols results in increased expression of JUN protein CTD PMID:8970189 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KIF20A kinesin family member 20A increases expression ISO Tocopherols results in increased expression of KIF20A mRNA CTD PMID:17056531 NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
JBrowse link
G KIF4A kinesin family member 4A increases expression ISO Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 NCBI chr  X:70,290,104...70,420,886
Ensembl chr  X:70,290,104...70,420,886
JBrowse link
G KLK3 kallikrein related peptidase 3 multiple interactions
decreases expression
EXP Tocopherols inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; Tocopherols inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]
[Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of KLK3 mRNA; Tocopherols results in decreased expression of KLK3 protein
CTD PMID:12032296 PMID:16302272 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases response to substance EXP MCL1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,574,551...150,579,738
Ensembl chr 1:150,574,551...150,579,738
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases activity
decreases expression
ISO Tocopherols results in decreased activity of MYC protein
Tocopherols results in decreased expression of MYC mRNA
CTD PMID:8970189 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAPB NSF attachment protein beta increases expression ISO Tocopherols results in increased expression of NAPB mRNA CTD PMID:17654050 NCBI chr20:23,374,522...23,421,498
Ensembl chr20:23,374,519...23,421,519
JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Tocopherols results in increased expression of NSF mRNA CTD PMID:17654050 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,464
JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression ISO Tocopherols results in decreased expression of PCNA CTD PMID:17927505 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha increases expression ISO Tocopherols results in increased expression of PPP3CA mRNA CTD PMID:17654050 NCBI chr 4:101,023,418...101,348,295
Ensembl chr 4:101,023,409...101,348,278
JBrowse link
G PRTN3 proteinase 3 increases expression ISO Tocopherols results in increased expression of PRTN3 mRNA CTD PMID:17056531 NCBI chr19:840,965...848,175
Ensembl chr19:840,999...848,175
JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O increases expression ISO Tocopherols results in increased expression of PTPRO mRNA CTD PMID:17056531 NCBI chr12:15,322,334...15,598,331
Ensembl chr12:15,322,508...15,598,331
Ensembl chr12:15,322,508...15,598,331
JBrowse link
G RAB11B RAB11B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB11B mRNA CTD PMID:17654050 NCBI chr19:8,390,360...8,404,434
Ensembl chr19:8,389,981...8,404,434
JBrowse link
G RAB3A RAB3A, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB3A mRNA CTD PMID:17654050 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042
JBrowse link
G RAB6B RAB6B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB6B mRNA CTD PMID:17654050 NCBI chr 3:133,824,235...133,895,882
Ensembl chr 3:133,824,235...133,895,882
JBrowse link
G RB1 RB transcriptional corepressor 1 decreases phosphorylation EXP Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 increases expression ISO Tocopherols results in increased expression of RRM1 mRNA CTD PMID:17056531 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
JBrowse link
G SNCA synuclein alpha increases expression ISO Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SNCB synuclein beta increases expression ISO Tocopherols results in increased expression of SNCB mRNA CTD PMID:17654050 NCBI chr 5:176,620,082...176,630,556
Ensembl chr 5:176,620,082...176,630,556
JBrowse link
G STX1A syntaxin 1A increases expression ISO Tocopherols results in increased expression of STX1A mRNA CTD PMID:17654050 NCBI chr 7:73,699,210...73,719,673
Ensembl chr 7:73,699,206...73,719,672
JBrowse link
G STXBP1 syntaxin binding protein 1 increases expression ISO Tocopherols results in increased expression of STXBP1 mRNA CTD PMID:17654050 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G SV2A synaptic vesicle glycoprotein 2A increases expression ISO Tocopherols results in increased expression of SV2A mRNA CTD PMID:17654050 NCBI chr 1:149,903,318...149,917,844
Ensembl chr 1:149,903,318...149,917,844
JBrowse link
G SYN1 synapsin I increases expression ISO Tocopherols results in increased expression of SYN1 mRNA CTD PMID:17654050 NCBI chr  X:47,571,901...47,619,857
Ensembl chr  X:47,571,901...47,619,857
JBrowse link
G SYN2 synapsin II increases expression ISO Tocopherols results in increased expression of SYN2 mRNA CTD PMID:17654050 NCBI chr 3:12,004,366...12,192,032
Ensembl chr 3:12,004,388...12,192,032
JBrowse link
G SYNGR1 synaptogyrin 1 increases expression ISO Tocopherols results in increased expression of SYNGR1 mRNA CTD PMID:17654050 NCBI chr22:39,349,991...39,385,575
Ensembl chr22:39,349,925...39,385,575
JBrowse link
G SYP synaptophysin increases expression ISO Tocopherols results in increased expression of SYP mRNA CTD PMID:17654050 NCBI chr  X:49,187,815...49,200,193
Ensembl chr  X:49,187,815...49,200,199
Ensembl chr  X:49,187,815...49,200,199
JBrowse link
G SYT11 synaptotagmin 11 increases expression ISO Tocopherols results in increased expression of SYT11 mRNA CTD PMID:17654050 NCBI chr 1:155,859,502...155,885,199
Ensembl chr 1:155,859,567...155,885,199
JBrowse link
G SYT13 synaptotagmin 13 increases expression ISO Tocopherols results in increased expression of SYT13 mRNA CTD PMID:17654050 NCBI chr11:45,240,302...45,286,341
Ensembl chr11:45,240,302...45,286,341
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Tocopherols inhibits the reaction [TNF protein results in decreased export of Potassium] CTD PMID:17337591 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP2 TNF alpha induced protein 2 increases expression ISO Tocopherols results in increased expression of TNFAIP2 mRNA CTD PMID:17056531 NCBI chr14:103,121,175...103,137,439
Ensembl chr14:103,121,476...103,137,439
Ensembl chr14:103,121,476...103,137,439
JBrowse link
G TP53 tumor protein p53 increases activity EXP Tocopherols results in increased activity of TP53 protein CTD PMID:15883045 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TTC3 tetratricopeptide repeat domain 3 increases expression ISO Tocopherols results in increased expression of TTC3 mRNA CTD PMID:17654050 NCBI chr21:37,073,235...37,203,118
Ensembl chr21:37,073,226...37,203,112
JBrowse link
G VAMP1 vesicle associated membrane protein 1 increases expression ISO Tocopherols results in increased expression of VAMP1 mRNA CTD PMID:17654050 NCBI chr12:6,462,237...6,470,677
Ensembl chr12:6,462,237...6,470,987
Ensembl chr12:6,462,237...6,470,987
JBrowse link
G VAMP2 vesicle associated membrane protein 2 increases expression ISO Tocopherols results in increased expression of VAMP2 mRNA CTD PMID:17654050 NCBI chr17:8,159,147...8,162,948
Ensembl chr17:8,159,149...8,163,546
JBrowse link
G VDR vitamin D receptor increases expression EXP Tocopherols results in increased expression of VDR mRNA CTD PMID:12032296 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
vitamin E term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AAMP angio associated migratory cell protein increases expression EXP Vitamin E results in increased expression of AAMP mRNA CTD PMID:19244175 NCBI chr 2:218,264,127...218,270,181
Ensembl chr 2:218,264,129...218,270,178
Ensembl chr 2:218,264,129...218,270,178
JBrowse link
G AASS aminoadipate-semialdehyde synthase multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNA
Vitamin E results in decreased expression of AASS mRNA
CTD PMID:19244175 NCBI chr 7:122,073,544...122,144,269
Ensembl chr 7:122,073,549...122,144,255
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein] CTD PMID:24448832 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA CTD PMID:11444866 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCD1 ATP binding cassette subfamily D member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD1 mRNA] CTD PMID:29065513 NCBI chr  X:153,724,851...153,744,755
Ensembl chr  X:153,724,856...153,744,755
JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD3 mRNA] CTD PMID:29065513 NCBI chr 1:94,418,086...94,518,663
Ensembl chr 1:94,418,389...94,518,666
JBrowse link
G ABHD14A abhydrolase domain containing 14A decreases expression EXP Vitamin E results in decreased expression of ABHD14A mRNA CTD PMID:19244175 NCBI chr 3:51,975,064...51,981,196
Ensembl chr 3:51,971,426...51,981,199
JBrowse link
G ABHD2 abhydrolase domain containing 2, acylglycerol lipase decreases expression
increases expression
EXP Vitamin E results in decreased expression of ABHD2 mRNA
Vitamin E results in increased expression of ABHD2 mRNA
CTD PMID:19244175 NCBI chr15:89,088,422...89,202,355
Ensembl chr15:89,087,459...89,202,355
JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression EXP Vitamin E results in increased expression of ABHD4 mRNA CTD PMID:19244175 NCBI chr14:22,598,238...22,612,864
Ensembl chr14:22,598,237...22,613,215
JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 increases expression EXP Vitamin E results in increased expression of ACAA2 mRNA CTD PMID:19244175 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
JBrowse link
G ACADS acyl-CoA dehydrogenase short chain multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of ACADS mRNA
Vitamin E results in increased expression of ACADS mRNA
CTD PMID:19244175 NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein] CTD PMID:10656290 NCBI chr11:108,116,705...108,148,822
Ensembl chr11:108,116,695...108,147,603
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
[Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]
CTD PMID:11814146 PMID:19464315 PMID:20663516 PMID:23619517 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACO2 aconitase 2 increases expression EXP Vitamin E results in increased expression of ACO2 mRNA CTD PMID:19244175 NCBI chr22:41,468,756...41,528,979
Ensembl chr22:41,469,117...41,528,989
Ensembl chr22:41,469,117...41,528,989
JBrowse link
G ACOT2 acyl-CoA thioesterase 2 multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of ACOT2 mRNA
Vitamin E results in increased expression of ACOT2 mRNA
CTD PMID:19244175 NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658
JBrowse link
G ACP1 acid phosphatase 1 decreases expression EXP Vitamin E results in decreased expression of ACP1 mRNA CTD PMID:19244175 NCBI chr 2:264,947...278,283
Ensembl chr 2:264,140...278,283
JBrowse link
G ACTA2 actin alpha 2, smooth muscle decreases expression EXP Vitamin E results in decreased expression of ACTA2 mRNA CTD PMID:19244175 NCBI chr10:88,935,074...88,991,397
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G ACTB actin beta increases expression EXP Vitamin E results in increased expression of ACTB mRNA CTD PMID:19244175 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ACTN4 actinin alpha 4 increases expression EXP Vitamin E results in increased expression of ACTN4 mRNA CTD PMID:19244175 NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589
JBrowse link
G ACTR1A actin related protein 1A increases expression EXP Vitamin E results in increased expression of ACTR1A mRNA CTD PMID:19244175 NCBI chr10:102,479,229...102,502,712
Ensembl chr10:102,461,881...102,502,712
JBrowse link
G ACTR1B actin related protein 1B increases expression EXP Vitamin E results in increased expression of ACTR1B mRNA CTD PMID:19244175 NCBI chr 2:97,655,939...97,664,044
Ensembl chr 2:97,655,939...97,664,044
JBrowse link
G ACVR2A activin A receptor type 2A decreases expression EXP Vitamin E results in decreased expression of ACVR2A mRNA CTD PMID:19244175 NCBI chr 2:147,844,517...147,930,822
Ensembl chr 2:147,844,517...147,930,826
JBrowse link
G ACVRL1 activin A receptor like type 1 increases expression ISO alpha-Tocopherol results in increased expression of ACVRL1 mRNA CTD PMID:16908007 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 decreases expression EXP Vitamin E results in decreased expression of ADAM17 mRNA CTD PMID:19244175 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 decreases expression EXP Vitamin E results in decreased expression of ADAMTS5 mRNA CTD PMID:19244175 NCBI chr21:26,917,922...26,967,758
Ensembl chr21:26,917,922...26,967,088
JBrowse link
G ADAP1 ArfGAP with dual PH domains 1 increases expression EXP Vitamin E results in increased expression of ADAP1 mRNA CTD PMID:19244175 NCBI chr 7:897,900...955,407
Ensembl chr 7:897,900...955,407
JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 decreases expression EXP Vitamin E results in decreased expression of ADARB1 mRNA CTD PMID:19244175 NCBI chr21:45,074,578...45,226,563
Ensembl chr21:45,073,853...45,226,560
JBrowse link
G ADCY2 adenylate cyclase 2 multiple interactions EXP [Selenium co-treated with Vitamin E] results in increased expression of ADCY2 mRNA CTD PMID:19244175 NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081
JBrowse link
G ADCY6 adenylate cyclase 6 increases expression EXP Vitamin E results in increased expression of ADCY6 mRNA CTD PMID:19244175 NCBI chr12:48,766,194...48,789,089
Ensembl chr12:48,766,194...48,789,037
JBrowse link
G ADD1 adducin 1 increases expression EXP Vitamin E results in increased expression of ADD1 mRNA CTD PMID:19244175 NCBI chr 4:2,843,844...2,930,065
Ensembl chr 4:2,843,857...2,930,076
JBrowse link
G ADD3 adducin 3 decreases expression EXP Vitamin E results in decreased expression of ADD3 mRNA CTD PMID:19244175 NCBI chr10:109,996,365...110,135,565
Ensembl chr10:109,996,368...110,135,565
JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 increases expression EXP Vitamin E results in increased expression of ADGRB1 mRNA CTD PMID:19244175 NCBI chr 8:142,449,649...142,545,009
Ensembl chr 8:142,449,430...142,545,009
JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression EXP Vitamin E results in decreased expression of ADH7 mRNA CTD PMID:19244175 NCBI chr 4:99,412,263...99,435,342
Ensembl chr 4:99,412,261...99,435,737
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions ISO Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ mRNA]; Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein] CTD PMID:20404018 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADRA2C adrenoceptor alpha 2C increases expression EXP Vitamin E results in increased expression of ADRA2C mRNA CTD PMID:19244175 NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526
JBrowse link
G ADRM1 adhesion regulating molecule 1 increases expression EXP Vitamin E results in increased expression of ADRM1 mRNA CTD PMID:19244175 NCBI chr20:62,302,061...62,308,862
Ensembl chr20:62,302,093...62,308,862
JBrowse link
G AEBP1 AE binding protein 1 increases expression EXP Vitamin E results in increased expression of AEBP1 mRNA CTD PMID:19244175 NCBI chr 7:44,104,320...44,114,564
Ensembl chr 7:44,104,345...44,114,562
JBrowse link
G AEN apoptosis enhancing nuclease increases expression EXP Vitamin E results in increased expression of AEN mRNA CTD PMID:19244175 NCBI chr15:88,604,601...88,632,281
Ensembl chr15:88,621,337...88,632,281
JBrowse link
G AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 decreases expression EXP Vitamin E results in decreased expression of AGAP4 mRNA CTD PMID:19244175 NCBI chr10:45,825,592...45,853,877
Ensembl chr10:45,825,594...45,853,875
JBrowse link
G AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 multiple interactions EXP [Selenium co-treated with Vitamin E] results in decreased expression of AGPAT2 mRNA CTD PMID:19244175 NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457
JBrowse link
G AGRN agrin decreases expression EXP Vitamin E results in decreased expression of AGRN mRNA CTD PMID:19244175 NCBI chr 1:1,020,102...1,056,119
Ensembl chr 1:1,020,120...1,056,118
JBrowse link
G AGT angiotensinogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein]; alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,702,523...230,714,122
JBrowse link
G AGTPBP1 ATP/GTP binding protein 1 decreases expression EXP Vitamin E results in decreased expression of AGTPBP1 mRNA CTD PMID:19244175 NCBI chr 9:85,546,539...85,742,029
Ensembl chr 9:85,546,539...85,742,029
JBrowse link
G AHNAK AHNAK nucleoprotein increases expression EXP Vitamin E results in increased expression of AHNAK mRNA CTD PMID:19244175 NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
JBrowse link
G AHNAK2 AHNAK nucleoprotein 2 increases expression EXP Vitamin E results in increased expression of AHNAK2 mRNA CTD PMID:19244175 NCBI chr14:104,937,253...104,978,374
Ensembl chr14:104,937,244...104,978,374
JBrowse link
G AHR aryl hydrocarbon receptor decreases expression EXP Vitamin E results in decreased expression of AHR mRNA CTD PMID:19244175 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AHSA1 activator of HSP90 ATPase activity 1 increases expression EXP Vitamin E results in increased expression of AHSA1 mRNA CTD PMID:19244175 NCBI chr14:77,457,867...77,469,472
Ensembl chr14:77,457,870...77,469,472
JBrowse link
G AIMP1 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of AIMP1 mRNA
Vitamin E results in decreased expression of AIMP1 mRNA
CTD PMID:19244175 NCBI chr 4:106,315,544...106,349,456
Ensembl chr 4:106,315,544...106,349,456
JBrowse link
G AK1 adenylate kinase 1 increases expression EXP Vitamin E results in increased expression of AK1 mRNA CTD PMID:19244175 NCBI chr 9:127,866,480...127,885,542
Ensembl chr 9:127,866,486...127,877,675
JBrowse link
G AK3 adenylate kinase 3 multiple interactions EXP [Selenium co-treated with Vitamin E] results in increased expression of AK3 mRNA CTD PMID:19244175 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
JBrowse link
G AKAP13 A-kinase anchoring protein 13 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of AKAP13 mRNA
Vitamin E results in decreased expression of AKAP13 mRNA
CTD PMID:19244175 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B increases expression ISO
EXP
alpha-Tocopherol results in increased expression of AKR1B1 mRNA
Vitamin E results in increased expression of AKR1B1 mRNA
CTD PMID:16908007 PMID:19244175 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 increases expression EXP Vitamin E results in increased expression of AKR1C2 mRNA CTD PMID:19244175 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,400...5,018,031
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of AKT1 protein]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
Vitamin E results in increased expression of AKT1 mRNA
CTD PMID:19244175 PMID:19351882 PMID:21911000 PMID:22343715 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein]
Vitamin E inhibits the reaction [lead acetate results in decreased activity of ALAD protein]
CTD PMID:2604901 PMID:7728901 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327
JBrowse link
G ALB albumin multiple interactions ISO
EXP
Vitamin E inhibits the reaction [Ethanol results in decreased expression of ALB protein]
[Quercetin co-treated with Vitamin E] inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]; alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]]; Vitamin E inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]
Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]
CTD PMID:17429802 PMID:17927767 PMID:21086752 PMID:23348005 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 decreases expression EXP Vitamin E results in decreased expression of ALDH6A1 mRNA CTD PMID:19244175 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A increases expression EXP Vitamin E results in increased expression of ALDOA mRNA CTD PMID:19244175 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G ALG3 ALG3 alpha-1,3- mannosyltransferase increases expression EXP Vitamin E results in increased expression of ALG3 mRNA CTD PMID:19244175 NCBI chr 3:184,242,301...184,258,301
Ensembl chr 3:184,242,301...184,249,548
JBrowse link
G ALG9 ALG9 alpha-1,2-mannosyltransferase multiple interactions EXP [Selenium co-treated with Vitamin E] results in increased expression of ALG9 mRNA CTD PMID:19244175 NCBI chr11:111,776,096...111,871,581
Ensembl chr11:111,782,195...111,871,581
JBrowse link
G ALKBH1 alkB homolog 1, histone H2A dioxygenase decreases expression EXP Vitamin E results in decreased expression of ALKBH1 mRNA CTD PMID:19244175 NCBI chr14:77,672,404...77,708,038
Ensembl chr14:77,672,404...77,708,023
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase decreases activity
multiple interactions
EXP
ISO
Vitamin E results in decreased activity of ALOX5 protein
[Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein
CTD PMID:11325678 PMID:12200813 PMID:22223226 NCBI chr10:45,374,209...45,446,121
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G AMBRA1 autophagy and beclin 1 regulator 1 increases expression EXP Vitamin E results in increased expression of AMBRA1 mRNA CTD PMID:19244175 NCBI chr11:46,396,412...46,594,055
Ensembl chr11:46,396,414...46,594,125
JBrowse link
G AMY2A amylase alpha 2A decreases expression EXP Vitamin E results in decreased expression of AMY2A mRNA CTD PMID:19244175 NCBI chr 1:103,617,427...103,625,780
Ensembl chr 1:103,616,811...103,625,780
JBrowse link
G ANAPC15 anaphase promoting complex subunit 15 increases expression EXP Vitamin E results in increased expression of ANAPC15 mRNA CTD PMID:19244175 NCBI chr11:72,106,372...72,112,780
Ensembl chr11:72,106,378...72,112,780
JBrowse link
G ANGPT1 angiopoietin 1 decreases expression EXP Vitamin E results in decreased expression of ANGPT1 mRNA CTD PMID:19244175 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G ANK3 ankyrin 3 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNA
Vitamin E results in decreased expression of ANK3 mRNA
CTD PMID:19244175 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490
JBrowse link
G ANKRD12 ankyrin repeat domain 12 decreases expression EXP Vitamin E results in decreased expression of ANKRD12 mRNA CTD PMID:19244175 NCBI chr18:9,136,767...9,285,985
Ensembl chr18:9,136,228...9,285,985
JBrowse link
G ANO6 anoctamin 6 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of ANO6 mRNA] CTD PMID:27886375 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G ANP32B acidic nuclear phosphoprotein 32 family member B multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of ANP32B mRNA
Vitamin E results in decreased expression of ANP32B mRNA
CTD PMID:19244175 NCBI chr 9:97,983,341...98,015,943
Ensembl chr 9:97,983,341...98,015,943
JBrowse link
G ANXA6 annexin A6 increases expression EXP Vitamin E results in increased expression of ANXA6 mRNA CTD PMID:19244175 NCBI chr 5:151,100,706...151,157,779
Ensembl chr 5:151,100,706...151,157,785
JBrowse link
G AP1M2 adaptor related protein complex 1 subunit mu 2 increases expression EXP Vitamin E results in increased expression of AP1M2 mRNA CTD PMID:19244175 NCBI chr19:10,572,671...10,587,315
Ensembl chr19:10,572,671...10,587,315
JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 increases expression EXP Vitamin E results in increased expression of AP2A2 mRNA CTD PMID:19244175 NCBI chr11:925,850...1,012,240
Ensembl chr11:924,894...1,012,245
JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Vitamin E results in increased expression of AP2M1 mRNA CTD PMID:19244175 NCBI chr 3:184,174,855...184,184,091
Ensembl chr 3:184,174,689...184,184,091
JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 increases expression EXP Vitamin E results in increased expression of AP2S1 mRNA CTD PMID:19244175 NCBI chr19:46,838,167...46,850,846
Ensembl chr19:46,838,136...46,850,992
Ensembl chr19:46,838,136...46,850,992
JBrowse link
G AP3S2 adaptor related protein complex 3 subunit sigma 2 increases expression EXP Vitamin E results in increased expression of AP3S2 mRNA CTD PMID:19244175 NCBI chr15:89,830,599...89,893,994
Ensembl chr15:89,830,599...89,894,638
JBrowse link
G APBB2 amyloid beta precursor protein binding family B member 2 decreases expression EXP Vitamin E results in decreased expression of APBB2 mRNA CTD PMID:19244175 NCBI chr 4:40,810,027...41,216,714
Ensembl chr 4:40,810,027...41,216,714
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP Vitamin E results in increased expression of APEX1 mRNA CTD PMID:19244175 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 multiple interactions
decreases expression
ISO alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA]
alpha-Tocopherol results in decreased expression of APEX2 mRNA
CTD PMID:26332274 NCBI chr  X:55,000,363...55,009,057
Ensembl chr  X:55,000,363...55,009,057
JBrowse link
G APLP2 amyloid beta precursor like protein 2 increases expression EXP Vitamin E results in increased expression of APLP2 mRNA CTD PMID:19244175 NCBI chr11:130,069,894...130,144,805
Ensembl chr11:130,068,147...130,144,811
JBrowse link
G APOA1 apolipoprotein A1 decreases expression
increases expression
decreases activity
EXP
ISO
alpha-Tocopherol results in decreased expression of APOA1 mRNA; alpha-Tocopherol results in decreased expression of APOA1 protein
Vitamin E results in increased expression of APOA1 protein
alpha-Tocopherol results in decreased activity of APOA1 promoter
CTD PMID:16423621 PMID:18458655 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOB apolipoprotein B multiple interactions EXP [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; alpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper]; Vitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Vitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]] CTD PMID:11368321 PMID:17237316 PMID:17475462 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOBEC3C apolipoprotein B mRNA editing enzyme catalytic subunit 3C decreases expression EXP Vitamin E results in decreased expression of APOBEC3C mRNA CTD PMID:19244175 NCBI chr22:39,014,236...39,020,352
Ensembl chr22:39,014,257...39,020,352
JBrowse link
G APOE apolipoprotein E multiple interactions ISO Vitamin E inhibits the reaction [APOE mutant form results in increased abundance of 8,12-iso-isoprostane F2alpha-VI] CTD PMID:16303615 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOL1 apolipoprotein L1 increases expression EXP Vitamin E results in increased expression of APOL1 mRNA CTD PMID:19244175 NCBI chr22:36,253,071...36,267,531
Ensembl chr22:36,253,010...36,267,530
Ensembl chr22:36,253,010...36,267,530
JBrowse link
G APOL3 apolipoprotein L3 increases expression EXP Vitamin E results in increased expression of APOL3 mRNA CTD PMID:19244175 NCBI chr22:36,140,323...36,166,177
Ensembl chr22:36,140,330...36,166,177
JBrowse link
G APOM apolipoprotein M increases expression EXP Vitamin E results in increased expression of APOM mRNA CTD PMID:19244175 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
JBrowse link
G APP amyloid beta precursor protein multiple interactions
decreases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein]
Vitamin E inhibits the reaction [APP protein modified form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]
Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein]
Vitamin E results in decreased expression of APP mRNA
CTD PMID:12039845 PMID:12117551 PMID:12684028 PMID:15223066 PMID:19244175 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G APPBP2 amyloid beta precursor protein binding protein 2 multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of APPBP2 mRNA
Vitamin E results in increased expression of APPBP2 mRNA
CTD PMID:19244175 NCBI chr17:60,443,149...60,526,242
Ensembl chr17:60,443,158...60,526,242
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) increases expression EXP Vitamin E results in increased expression of AQP1 mRNA CTD PMID:19244175 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
G AQP3 aquaporin 3 (Gill blood group) increases expression
multiple interactions
EXP Vitamin E results in increased expression of AQP3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AQP3 mRNA
CTD PMID:19244175 NCBI chr 9:33,441,154...33,447,596
Ensembl chr 9:33,441,156...33,447,596
JBrowse link
G AQP4 aquaporin 4 multiple interactions ISO Vitamin E inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein]
Vitamin E inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]
CTD PMID:20648640 PMID:30914277 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
JBrowse link
G ARAF A-Raf proto-oncogene, serine/threonine kinase multiple interactions EXP [Selenium co-treated with Vitamin E] results in increased expression of ARAF mRNA CTD PMID:19244175 NCBI chr  X:47,561,205...47,571,908
Ensembl chr  X:47,561,100...47,571,920
JBrowse link
G ARF3 ADP ribosylation factor 3 increases expression EXP Vitamin E results in increased expression of ARF3 mRNA CTD PMID:19244175 NCBI chr12:48,930,252...48,957,526
Ensembl chr12:48,935,723...48,957,487
JBrowse link
G ARF5 ADP ribosylation factor 5 increases expression EXP Vitamin E results in increased expression of ARF5 mRNA CTD PMID:19244175 NCBI chr 7:127,588,411...127,591,700
Ensembl chr 7:127,588,386...127,591,700
JBrowse link
G ARHGAP10 Rho GTPase activating protein 10 increases expression EXP Vitamin E results in increased expression of ARHGAP10 mRNA CTD PMID:19244175 NCBI chr 4:147,732,063...148,072,781
Ensembl chr 4:147,732,063...148,072,776
JBrowse link
G ARHGAP8 Rho GTPase activating protein 8 increases expression EXP Vitamin E results in increased expression of ARHGAP8 mRNA CTD PMID:19244175 NCBI chr22:44,752,575...44,862,784
Ensembl chr22:44,752,558...44,862,788
JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha increases expression EXP Vitamin E results in increased expression of ARHGDIA mRNA CTD PMID:19244175 NCBI chr17:81,867,719...81,871,337
Ensembl chr17:81,867,721...81,871,378
JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 decreases expression EXP Vitamin E results in decreased expression of ARIH1 mRNA CTD PMID:19244175 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
JBrowse link
G ARL4D ADP ribosylation factor like GTPase 4D increases expression EXP Vitamin E results in increased expression of ARL4D mRNA CTD PMID:19244175 NCBI chr17:43,398,993...43,401,137
Ensembl chr17:43,398,993...43,401,137
JBrowse link
G ARL6IP4 ADP ribosylation factor like GTPase 6 interacting protein 4 increases expression EXP Vitamin E results in increased expression of ARL6IP4 mRNA CTD PMID:19244175 NCBI chr12:122,980,233...122,982,909
Ensembl chr12:122,980,060...122,982,913
JBrowse link
G ARPC1A actin related protein 2/3 complex subunit 1A increases expression EXP Vitamin E results in increased expression of ARPC1A mRNA CTD PMID:19244175 NCBI chr 7:99,325,898...99,366,262
Ensembl chr 7:99,325,898...99,366,262
JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 increases expression EXP Vitamin E results in increased expression of ARPC4 mRNA CTD PMID:19244175 NCBI chr 3:9,792,518...9,807,101
Ensembl chr 3:9,792,495...9,807,726
JBrowse link
G ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 increases expression EXP Vitamin E results in increased expression of ASAP3 mRNA CTD PMID:19244175 NCBI chr 1:23,428,563...23,484,631
Ensembl chr 1:23,428,563...23,484,568
JBrowse link
G ASB1 ankyrin repeat and SOCS box containing 1 multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of ASB1 mRNA
Vitamin E results in increased expression of ASB1 mRNA
CTD PMID:19244175 NCBI chr 2:238,426,927...238,452,250
Ensembl chr 2:238,426,742...238,452,250
JBrowse link
G ASXL1 ASXL transcriptional regulator 1 decreases expression EXP Vitamin E results in decreased expression of ASXL1 mRNA CTD PMID:19244175 NCBI chr20:32,358,062...32,439,319
Ensembl chr20:32,358,330...32,439,319
JBrowse link
G ATF2 activating transcription factor 2 multiple interactions
increases phosphorylation
EXP alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of ATF2 protein]
Vitamin E results in increased phosphorylation of ATF2 protein
CTD PMID:11522656 PMID:14645110 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
JBrowse link
G ATF3 activating transcription factor 3 decreases expression EXP Vitamin E results in decreased expression of ATF3 mRNA CTD PMID:19244175 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF5 activating transcription factor 5 multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of ATF5 mRNA
Vitamin E results in increased expression of ATF5 mRNA
CTD PMID:19244175 NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935
JBrowse link
G ATG12 autophagy related 12 decreases expression EXP Vitamin E results in decreased expression of ATG12 mRNA CTD PMID:19244175 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
JBrowse link
G ATMIN ATM interactor multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of ATMIN mRNA
Vitamin E results in decreased expression of ATMIN mRNA
CTD PMID:19244175 NCBI chr16:81,035,842...81,047,350
Ensembl chr16:81,035,842...81,047,350
JBrowse link
G ATOX1 antioxidant 1 copper chaperone increases expression EXP Vitamin E results in increased expression of ATOX1 mRNA CTD PMID:19244175 NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta increases expression EXP Vitamin E results in increased expression of ATP5F1B mRNA CTD PMID:19244175 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G ATP5F1C ATP synthase F1 subunit gamma decreases expression EXP Vitamin E results in decreased expression of ATP5F1C mRNA CTD PMID:19244175 NCBI chr10:7,788,159...7,807,801
Ensembl chr10:7,788,147...7,807,815
JBrowse link
G ATP5ME ATP synthase membrane subunit e decreases expression EXP Vitamin E results in decreased expression of ATP5ME mRNA CTD PMID:19244175 NCBI chr 4:672,436...674,276
Ensembl chr 4:672,436...674,330
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 decreases expression EXP Vitamin E results in decreased expression of ATP6AP2 mRNA CTD PMID:19244175 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0D1 ATPase H+ transporting V0 subunit d1 increases expression EXP Vitamin E results in increased expression of ATP6V0D1 mRNA CTD PMID:19244175 NCBI chr16:67,438,019...67,481,157
Ensembl chr16:67,438,014...67,481,181
JBrowse link
G ATP6V1C1 ATPase H+ transporting V1 subunit C1 decreases expression EXP Vitamin E results in decreased expression of ATP6V1C1 mRNA CTD PMID:19244175 NCBI chr 8:103,021,083...103,073,051
Ensembl chr 8:103,021,063...103,073,051
JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 decreases expression EXP Vitamin E results in decreased expression of ATP8B1 mRNA CTD PMID:19244175 NCBI chr18:57,646,426...57,803,822
Ensembl chr18:57,646,426...57,803,315
JBrowse link
G ATRX ATRX chromatin remodeler decreases expression
multiple interactions
EXP Vitamin E results in decreased expression of ATRX mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA
CTD PMID:19244175 NCBI chr  X:77,504,880...77,786,235
Ensembl chr  X:77,504,880...77,786,233
Ensembl chr  X:77,504,880...77,786,233
JBrowse link
G ATXN3 ataxin 3 decreases expression EXP Vitamin E results in decreased expression of ATXN3 mRNA CTD PMID:19244175 NCBI chr14:92,058,552...92,106,582
Ensembl chr14:92,044,496...92,106,621
JBrowse link
G ATXN7 ataxin 7 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of ATXN7 mRNA
Vitamin E results in decreased expression of ATXN7 mRNA
CTD PMID:19244175 NCBI chr 3:63,863,144...64,003,462
Ensembl chr 3:63,863,155...64,003,462
Ensembl chr 3:63,863,155...64,003,462
Ensembl chr 3:63,863,155...64,003,462
Ensembl chr 3:63,863,155...64,003,462
JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 decreases expression EXP Vitamin E results in decreased expression of AUTS2 mRNA CTD PMID:19244175 NCBI chr 7:69,598,475...70,793,506
Ensembl chr 7:69,598,296...70,793,506
JBrowse link
G AXL AXL receptor tyrosine kinase decreases expression EXP Vitamin E results in decreased expression of AXL mRNA CTD PMID:19244175 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766
JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase increases expression ISO Vitamin E results in increased expression of BAAT mRNA CTD PMID:28923436 NCBI chr 9:101,360,417...101,385,006
Ensembl chr 9:101,354,182...101,385,400
Ensembl chr 9:101,354,182...101,385,400
JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 increases expression EXP Vitamin E results in increased expression of BABAM1 mRNA CTD PMID:19244175 NCBI chr19:17,267,443...17,279,337
Ensembl chr19:17,267,418...17,282,966
Ensembl chr19:17,267,418...17,282,966
JBrowse link
G BABAM2 BRISC and BRCA1 A complex member 2 increases expression EXP Vitamin E results in increased expression of BABAM2 mRNA CTD PMID:19244175 NCBI chr 2:27,888,709...28,338,901
Ensembl chr 2:27,889,941...28,338,901
JBrowse link
G BACE1 beta-secretase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,207...117,316,259
JBrowse link
G BAD BCL2 associated agonist of cell death increases expression ISO alpha-Tocopherol results in increased expression of BAD mRNA CTD PMID:26332274 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAG5 BAG cochaperone 5 decreases expression EXP Vitamin E results in decreased expression of BAG5 mRNA CTD PMID:19244175 NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,544...103,562,831
JBrowse link
G BAG6 BAG cochaperone 6 increases expression EXP Vitamin E results in increased expression of BAG6 mRNA CTD PMID:19244175 NCBI chr 6:31,639,028...31,660,900
Ensembl chr 6:31,639,028...31,652,705
JBrowse link
G BANF1 BAF nuclear assembly factor 1 increases expression EXP Vitamin E results in increased expression of BANF1 mRNA CTD PMID:19244175 NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149
JBrowse link
G BAP1 BRCA1 associated protein 1 increases expression EXP Vitamin E results in increased expression of BAP1 mRNA CTD PMID:19244175 NCBI chr 3:52,401,004...52,410,030
Ensembl chr 3:52,401,008...52,410,008
JBrowse link
G BARD1 BRCA1 associated RING domain 1 decreases expression EXP Vitamin E results in decreased expression of BARD1 mRNA CTD PMID:19244175 NCBI chr 2:214,725,645...214,809,683
Ensembl chr 2:214,725,646...214,809,683
JBrowse link
G BATF basic leucine zipper ATF-like transcription factor increases expression EXP Vitamin E results in increased expression of BATF mRNA CTD PMID:19244175 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993
Ensembl chr14:75,522,455...75,546,993
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
affects expression
ISO
EXP
alpha-Tocopherol results in increased expression of BAX mRNA
[Vitamin E co-treated with Folic Acid] affects the expression of BAX protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased expression of BAX protein]
Vitamin E affects the expression of BAX protein
Vitamin E results in increased expression of BAX protein
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in increased expression of BAX protein]; Vitamin E inhibits the reaction [cinnamic aldehyde results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of BAX protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased expression of BAX protein]
CTD PMID:11166918 PMID:11805214 PMID:15566391 PMID:16054126 PMID:16933212 PMID:22020378 PMID:23523949 PMID:26332274 PMID:27353299 PMID:30935902 PMID:32134168 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BAZ1A bromodomain adjacent to zinc finger domain 1A decreases expression EXP Vitamin E results in decreased expression of BAZ1A mRNA CTD PMID:19244175 NCBI chr14:34,752,731...34,875,360
Ensembl chr14:34,752,731...34,875,647
JBrowse link
G BAZ1B bromodomain adjacent to zinc finger domain 1B increases expression EXP Vitamin E results in increased expression of BAZ1B mRNA CTD PMID:19244175 NCBI chr 7:73,440,406...73,522,293
Ensembl chr 7:73,440,406...73,522,293
JBrowse link
G BBX BBX high mobility group box domain containing multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of BBX mRNA
Vitamin E results in decreased expression of BBX mRNA
CTD PMID:19244175 NCBI chr 3:107,522,962...107,811,339
Ensembl chr 3:107,522,936...107,811,339
JBrowse link
G BCAP31 B cell receptor associated protein 31 increases expression EXP Vitamin E results in increased expression of BCAP31 mRNA CTD PMID:19244175 NCBI chr  X:153,700,492...153,724,746
Ensembl chr  X:153,700,492...153,724,565
JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; alpha-Tocopherol inhibits the reaction [Endosulfan results in decreased activity of BCHE protein]; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein] CTD PMID:20663516 PMID:24299906 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A decreases expression EXP Vitamin E results in decreased expression of BCL11A mRNA CTD PMID:19244175 NCBI chr 2:60,450,520...60,553,654
Ensembl chr 2:60,450,520...60,554,467
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
increases expression
multiple interactions
EXP
ISO
alpha-Tocopherol analog results in decreased expression of BCL2 mRNA; alpha-Tocopherol analog results in decreased expression of BCL2 protein
Vitamin E results in increased expression of BCL2 mRNA
[Vitamin E co-treated with Folic Acid] affects the expression of BCL2 protein; alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of BCL2 protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased expression of BCL2 protein]
[Vitamin E co-treated with Curcumin] results in decreased expression of BCL2 protein; alpha-Tocopherol affects the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; TNFRSF10B mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BCL2 protein]
CTD PMID:11805214 PMID:15566391 PMID:16005924 PMID:16135673 PMID:16933212 PMID:20686688 PMID:22020378 PMID:27353299 PMID:30935902 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression
increases expression
multiple interactions
ISO
EXP
alpha-Tocopherol results in decreased expression of BCL2L1 protein
Vitamin E results in increased expression of BCL2L1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BCL2L1 mRNA
CTD PMID:11444866 PMID:18942769 PMID:19244175 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL6 BCL6 transcription repressor decreases expression EXP Vitamin E results in decreased expression of BCL6 mRNA CTD PMID:19244175 NCBI chr 3:187,721,377...187,745,472
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G BCLAF1 BCL2 associated transcription factor 1 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of BCLAF1 mRNA
Vitamin E results in decreased expression of BCLAF1 mRNA
CTD PMID:19244175 NCBI chr 6:136,256,627...136,289,846
Ensembl chr 6:136,256,627...136,289,851
JBrowse link
G BCO1 beta-carotene oxygenase 1 multiple interactions ISO Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]] CTD PMID:9526112 NCBI chr16:81,238,448...81,291,142
Ensembl chr16:81,238,689...81,291,142
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased expression of BDNF protein] CTD PMID:30776390 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 multiple interactions
decreases expression
ISO Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 mRNA]; Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 protein]
Vitamin E results in decreased expression of BECN1 protein
CTD PMID:19138675 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BICD1 BICD cargo adaptor 1 decreases expression
multiple interactions
EXP Vitamin E results in decreased expression of BICD1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of BICD1 mRNA
CTD PMID:19244175 NCBI chr12:32,106,773...32,383,637
Ensembl chr12:32,106,835...32,383,633
JBrowse link
G BICD2 BICD cargo adaptor 2 decreases expression EXP Vitamin E results in decreased expression of BICD2 mRNA CTD PMID:19244175 NCBI chr 9:92,711,363...92,764,841
Ensembl chr 9:92,711,363...92,764,833
JBrowse link
G BIN1 bridging integrator 1 increases expression EXP Vitamin E results in increased expression of BIN1 mRNA CTD PMID:19244175 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 multiple interactions ISO
EXP
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNA
Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BIRC2 protein]
CTD PMID:11444866 PMID:15566391 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 multiple interactions EXP Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BIRC3 protein] CTD PMID:15566391 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions EXP Vitamin E inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein] CTD PMID:24664296 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BLVRA biliverdin reductase A increases expression EXP Vitamin E results in increased expression of BLVRA mRNA CTD PMID:19244175 NCBI chr 7:43,758,122...43,807,342
Ensembl chr 7:43,758,680...43,807,342
JBrowse link
G BMP2K BMP2 inducible kinase decreases expression EXP Vitamin E results in decreased expression of BMP2K mRNA CTD PMID:19244175 NCBI chr 4:78,776,350...78,916,365
Ensembl chr 4:78,776,342...78,916,372
JBrowse link
G BMP4 bone morphogenetic protein 4 increases expression EXP Vitamin E results in increased expression of BMP4 mRNA CTD PMID:19244175 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BPTF bromodomain PHD finger transcription factor multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of BPTF mRNA
Vitamin E results in decreased expression of BPTF mRNA
CTD PMID:19244175 NCBI chr17:67,825,503...67,984,378
Ensembl chr17:67,825,503...67,984,378
JBrowse link
G BRD2 bromodomain containing 2 multiple interactions
increases expression
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA
Vitamin E results in increased expression of BRD2 mRNA
Vitamin E results in decreased expression of BRD2 mRNA
CTD PMID:19244175 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
JBrowse link
G BRF2 BRF2 RNA polymerase III transcription initiation factor subunit increases expression EXP Vitamin E results in increased expression of BRF2 mRNA CTD PMID:19244175 NCBI chr 8:37,843,268...37,849,861
Ensembl chr 8:37,843,268...37,849,861
JBrowse link
G BRMS1 BRMS1 transcriptional repressor and anoikis regulator increases expression EXP Vitamin E results in increased expression of BRMS1 mRNA CTD PMID:19244175 NCBI chr11:66,337,333...66,345,125
Ensembl chr11:66,337,333...66,345,125
JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of BSCL2 mRNA
Vitamin E results in increased expression of BSCL2 mRNA
CTD PMID:19244175 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,690,275...62,709,845
JBrowse link
G BST2 bone marrow stromal cell antigen 2 increases expression EXP Vitamin E results in increased expression of BST2 mRNA CTD PMID:19244175 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
JBrowse link
G C11orf68 chromosome 11 open reading frame 68 increases expression EXP Vitamin E results in increased expression of C11ORF68 mRNA CTD PMID:19244175 NCBI chr11:65,916,810...65,919,062
Ensembl chr11:65,916,810...65,919,062
JBrowse link
G C12orf4 chromosome 12 open reading frame 4 decreases expression EXP Vitamin E results in decreased expression of C12ORF4 mRNA CTD PMID:19244175 NCBI chr12:4,487,735...4,538,508
Ensembl chr12:4,487,735...4,538,508
JBrowse link
G C19orf73 chromosome 19 open reading frame 73 increases expression EXP Vitamin E results in increased expression of C19ORF73 mRNA CTD PMID:19244175 NCBI chr19:49,118,402...49,119,143
Ensembl chr19:49,118,402...49,119,143
JBrowse link
G C1orf216 chromosome 1 open reading frame 216 increases expression EXP Vitamin E results in increased expression of C1ORF216 mRNA CTD PMID:19244175 NCBI chr 1:35,713,877...35,718,884
Ensembl chr 1:35,713,877...35,718,894
JBrowse link
G C1orf50 chromosome 1 open reading frame 50 decreases expression
multiple interactions
EXP Vitamin E results in decreased expression of C1ORF50 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of C1ORF50 mRNA
CTD PMID:19244175 NCBI chr 1:42,767,249...42,779,491
Ensembl chr 1:42,767,249...42,779,491
JBrowse link
G C1S complement C1s increases expression EXP Vitamin E results in increased expression of C1S mRNA CTD PMID:19244175 NCBI chr12:7,060,718...7,071,032
Ensembl chr12:6,988,259...7,071,032
JBrowse link
G C20orf27 chromosome 20 open reading frame 27 increases expression
multiple interactions
EXP Vitamin E results in increased expression of C20ORF27 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of C20ORF27 mRNA
CTD PMID:19244175 NCBI chr20:3,753,508...3,768,388
Ensembl chr20:3,753,508...3,768,387
Ensembl chr20:3,753,508...3,768,387
JBrowse link
G C2orf42 chromosome 2 open reading frame 42 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of C2ORF42 mRNA
Vitamin E results in decreased expression of C2ORF42 mRNA
CTD PMID:19244175 NCBI chr 2:70,149,885...70,191,026
Ensembl chr 2:70,149,880...70,248,615
Ensembl chr 2:70,149,880...70,248,615
JBrowse link
G C7orf26 chromosome 7 open reading frame 26 increases expression EXP Vitamin E results in increased expression of C7ORF26 mRNA CTD PMID:19244175 NCBI chr 7:6,590,021...6,608,726
Ensembl chr 7:6,590,021...6,608,726
JBrowse link
G C8orf33 chromosome 8 open reading frame 33 increases expression EXP Vitamin E results in increased expression of C8ORF33 mRNA CTD PMID:19244175 NCBI chr 8:145,052,467...145,065,864
Ensembl chr 8:145,052,465...145,066,685
JBrowse link
G CA3 carbonic anhydrase 3 multiple interactions ISO [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CA3 mRNA CTD PMID:11444866 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
JBrowse link
G CAAP1 caspase activity and apoptosis inhibitor 1 decreases expression EXP Vitamin E results in decreased expression of CAAP1 mRNA CTD PMID:19244175 NCBI chr 9:26,840,685...26,892,808
Ensembl chr 9:26,840,685...26,892,803
JBrowse link
G CAB39 calcium binding protein 39 increases expression EXP Vitamin E results in increased expression of MO25 mRNA CTD PMID:19244175 NCBI chr 2:230,712,842...230,821,075
Ensembl chr 2:230,712,842...230,821,075
JBrowse link
G CALD1 caldesmon 1 decreases expression EXP Vitamin E results in decreased expression of CALD1 mRNA CTD PMID:19244175 NCBI chr 7:134,779,629...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CALM3 calmodulin 3 increases expression EXP Vitamin E results in increased expression of CALM3 mRNA CTD PMID:19244175 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G CALR calreticulin multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of CALR mRNA
Vitamin E results in decreased expression of CALR mRNA
CTD PMID:19244175 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CALU calumenin multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of CALU mRNA
Vitamin E results in increased expression of CALU mRNA
CTD PMID:19244175 NCBI chr 7:128,739,359...128,773,400
Ensembl chr 7:128,739,292...128,773,400
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta increases expression EXP Vitamin E results in increased expression of CAMK2B mRNA CTD PMID:19244175 NCBI chr 7:44,217,154...44,326,167
Ensembl chr 7:44,217,150...44,334,577
JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma decreases expression EXP Vitamin E results in decreased expression of CAMK2G mRNA CTD PMID:19244175 NCBI chr10:73,812,501...73,874,582
Ensembl chr10:73,812,501...73,874,591
JBrowse link
G CANX calnexin affects localization
increases expression
ISO alpha-Tocopherol affects the localization of CANX protein
alpha-Tocopherol results in increased expression of CANX mRNA; alpha-Tocopherol results in increased expression of CANX protein
CTD PMID:16908007 NCBI chr 5:179,678,646...179,731,641
Ensembl chr 5:179,678,628...179,731,641
JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 increases expression EXP Vitamin E results in increased expression of CAP1 mRNA CTD PMID:19244175 NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649
JBrowse link
G CAPG capping actin protein, gelsolin like increases expression EXP Vitamin E results in increased expression of CAPG mRNA CTD PMID:19244175 NCBI chr 2:85,394,753...85,418,467
Ensembl chr 2:85,394,753...85,418,432
JBrowse link
G CAPN7 calpain 7 decreases expression EXP Vitamin E results in decreased expression of CAPN7 mRNA CTD PMID:19244175 NCBI chr 3:15,206,246...15,252,916
Ensembl chr 3:15,206,152...15,252,916
JBrowse link
G CAPNS1 calpain small subunit 1 increases expression EXP Vitamin E results in increased expression of CAPNS1 mRNA CTD PMID:19244175 NCBI chr19:36,140,066...36,150,353
Ensembl chr19:36,139,953...36,150,353
JBrowse link
G CAPRIN2 caprin family member 2 decreases expression EXP Vitamin E results in decreased expression of CAPRIN2 mRNA CTD PMID:19244175 NCBI chr12:30,709,552...30,754,951
Ensembl chr12:30,709,552...30,754,951
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta increases expression EXP Vitamin E results in increased expression of CAPZB mRNA CTD PMID:19244175 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G CASC3 CASC3 exon junction complex subunit multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in increased expression of MLN51 mRNA
Vitamin E results in increased expression of MLN51 mRNA
CTD PMID:19244175 NCBI chr17:40,140,506...40,172,172
Ensembl chr17:40,140,318...40,172,171
JBrowse link
G CASP3 caspase 3 decreases activity
multiple interactions
EXP
ISO
alpha-Tocopherol results in decreased activity of CASP3 protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased cleavage of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; Vitamin E inhibits the reaction [titanium dioxide results in increased activity of CASP3 protein]
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; alpha-Tocopherol inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]; Vitamin E inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]
[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein; [alpha-Tocopherol co-treated with Tretinoin] results in increased activity of CASP3 protein; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Acetaldehyde results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP3 protein; Vitamin E inhibits the reaction [cinnamic aldehyde results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; Vitamin E inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased activity of CASP3 protein]
CTD PMID:12117551 PMID:12450566 PMID:14599462 PMID:14722101 PMID:15095415 PMID:15566391 PMID:16054126 PMID:16973328 PMID:17618090 PMID:17874176 PMID:17936189 PMID:21628957 PMID:21869839 PMID:21873648 PMID:22020378 PMID:22389237 PMID:23042730 PMID:23523949 PMID:27353299 PMID:28237877 PMID:29065513 PMID:29129777 PMID:30626778 PMID:30776390 PMID:30935902 PMID:31712109 PMID:32134168 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP7 caspase 7 multiple interactions EXP alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]] CTD PMID:23042730 PMID:29129777 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 increases cleavage EXP alpha-Tocopherol analog results in increased cleavage of CASP8 protein CTD PMID:20686688 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 increases cleavage
multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol analog results in increased cleavage of CASP9 protein
alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]
Vitamin E results in increased expression of CASP9 mRNA
alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP9 protein
CTD PMID:16973328 PMID:19244175 PMID:20686688 PMID:21628957 PMID:21869839 PMID:27353299 PMID:31712109 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase increases expression
multiple interactions
decreases activity
affects expression
increases activity
EXP
ISO
alpha-Tocopherol results in increased expression of CAT mRNA; alpha-Tocopherol results in increased expression of CAT protein
alpha-Tocopherol results in increased expression of CAT protein; Vitamin E results in increased expression of CAT protein
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] results in increased activity of CAT protein; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; [Vitamin E co-treated with Quercetin] inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; [Vitamin E co-treated with Sodium Selenite] inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; [Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]] which affects the abundance of Reactive Oxygen Species; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; alpha-Tocopherol affects the reaction [Copper Sulfate results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Ginkgo biloba extract promotes the reaction [Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Carbofuran results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Food Additives affects the activity of CAT protein]; Vitamin E inhibits the reaction [Formaldehyde results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Methoxychlor results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Petroleum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of CAT protein]; Vitamin E promotes the reaction [Ginkgo biloba extract inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]
Vitamin E results in decreased activity of CAT protein
[Vitamin E co-treated with coenzyme Q10] inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [fipronil results in decreased activity of CAT protein]
Vitamin E affects the expression of CAT protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; Vitamin E inhibits the reaction [Aluminum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]
alpha-Tocopherol results in increased activity of CAT protein
CTD PMID:9306888 PMID:11597945 PMID:11834209 PMID:11955947 PMID:12355564 PMID:14535831 PMID:15669049 PMID:15820619 PMID:16144695 PMID:16298753 PMID:16758767 PMID:16937016 PMID:16979807 PMID:17262218 PMID:17383094 PMID:17709913 PMID:17927767 PMID:18547560 PMID:18655177 PMID:19083475 PMID:19464315 PMID:19914224 PMID:19941068 PMID:19958828 PMID:20077558 PMID:20079796 PMID:20194575 PMID:20535553 PMID:21086752 PMID:21322096 PMID:21628957 PMID:21736874 PMID:21787585 PMID:22020378 PMID:22207723 PMID:22732938 PMID:23348005 PMID:23369933 PMID:23619517 PMID:24865641 PMID:25046308 PMID:25721553 PMID:27823922 PMID:29948670 PMID:30057697 PMID:31022331 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 multiple interactions EXP
ISO
alpha-Tocopherol inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA]
Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAV1 protein]
CTD PMID:12134086 PMID:27257344 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CAVIN1 caveolae associated protein 1 multiple interactions
increases expression
EXP Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAVIN1 protein]
Vitamin E results in increased expression of CAVIN1 mRNA
CTD PMID:19244175 PMID:21705337 NCBI chr17:42,402,449...42,423,269
Ensembl chr17:42,402,449...42,423,256
JBrowse link
G CAVIN3 caveolae associated protein 3 increases expression EXP Vitamin E results in increased expression of CAVIN3 mRNA CTD PMID:19244175 NCBI chr11:6,318,946...6,320,501
Ensembl chr11:6,318,946...6,320,532
JBrowse link
G CBLB Cbl proto-oncogene B decreases expression EXP Vitamin E results in decreased expression of CBLB mRNA CTD PMID:19244175 NCBI chr 3:105,655,461...105,869,552
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CBX5 chromobox 5 multiple interactions
decreases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of CBX5 mRNA
Vitamin E results in decreased expression of CBX5 mRNA
CTD PMID:19244175 NCBI chr12:54,230,942...54,280,122
Ensembl chr12:54,230,942...54,280,133
JBrowse link
G CBX6 chromobox 6 increases expression EXP Vitamin E results in increased expression of CBX6 mRNA CTD PMID:19244175 NCBI chr22:38,861,422...38,872,216
Ensembl chr22:38,861,422...38,872,249
JBrowse link
G CBX7 chromobox 7 increases expression EXP Vitamin E results in increased expression of CBX7 mRNA CTD PMID:19244175 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680
JBrowse link
G CBY1 chibby family member 1, beta catenin antagonist increases expression EXP Vitamin E results in increased expression of CBY1 mRNA CTD PMID:19244175 NCBI chr22:38,656,638...38,673,850
Ensembl chr22:38,656,636...38,673,854
JBrowse link
G CCDC85B coiled-coil domain containing 85B multiple interactions
increases expression
EXP [Selenium co-treated with Vitamin E] results in decreased expression of DIPA mRNA
Vitamin E results in increased expression of DIPA mRNA
CTD PMID:19244175 NCBI chr11:65,890,673...65,891,635
Ensembl chr11:65,890,673...65,891,635
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G CCHCR1 coiled-coil alpha-helical rod protein 1 increases expression EXP Vitamin E results in increased expression of CCHCR1 mRNA CTD PMID:19244175 NCBI chr 6:31,142,439...31,158,231
Ensembl chr 6:31,142,439...31,158,238
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G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD PMID:19735175 PMID:24333275 PMID:26332274 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
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G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNA CTD PMID:16797527 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G CCND1 cyclin D1 increases expression
multiple interactions
affects expression
EXP
ISO
Vitamin E results in increased expression of CCND1 mRNA
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]
Vitamin E affects the expression of CCND1 mRNA; Vitamin E affects the expression of CCND1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CCND1 mRNA; alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA]
CTD PMID:11444866 PMID:16298738 PMID:19244175 PMID:26332274 PMID:30935902 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G CCND2 cyclin D2 multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA]
Vitamin E results in increased expression of CCND2 mRNA
CTD PMID:19244175 PMID:26332274 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
Ensembl chr12:4,269,771...4,305,353
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G CCND3 cyclin D3 affects expression ISO Vitamin E affects the expression of CCND3 mRNA CTD PMID:15370891 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCNE1 cyclin E1 affects expression ISO Vitamin E affects the expression of CCNE1 mRNA CTD PMID:16298738 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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G CCNL1 cyclin L1 decreases expression EXP Vitamin E results in decreased expression of CCNL1 mRNA CTD PMID:19244175 NCBI chr 3:157,143,121...157,160,180
Ensembl chr 3:157,146,508...157,160,760
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G CCPG1 cell cycle progression 1 decreases expression EXP Vitamin E results in decreased expression of CPR8 mRNA CTD PMID:19244175 NCBI chr15:55,355,239...55,408,359
Ensembl chr15:55,340,032...55,408,510
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G CCS copper chaperone for superoxide dismutase increases expression EXP Vitamin E results in increased expression of CCS mRNA CTD PMID:19244175 NCBI chr11:66,593,162...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G CD1C CD1c molecule increases expression EXP Vitamin E results in increased expression of CD1C mRNA CTD PMID:19244175 NCBI chr 1:158,289,887...158,294,774
Ensembl chr 1:158,289,923...158,294,774
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G CD2BP2 CD2 cytoplasmic tail binding protein 2 increases expression EXP Vitamin E results in increased expression of CD2BP2 mRNA CTD PMID:19244175 NCBI chr16:30,350,773...30,355,308
Ensembl chr16:30,350,773...30,355,308
JBrowse link
G CD36 CD36 molecule affects expression
multiple interactions
ISO alpha-Tocopherol affects the expression of CD36 mRNA
alpha-Tocopherol inhibits the reaction [[troglitazone co-treated with Ethanol] results in increased expression of CD36 protein]
CTD PMID:16407258 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G