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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chromanol
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Accession:CHEBI:23229 term browser browse the term
Definition:Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.


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(R,R,R)-alpha-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein] CTD PMID:24448832 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD1 mRNA] CTD PMID:29065513 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD3 mRNA] CTD PMID:29065513 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein] CTD PMID:10656290 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:19464315 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP alpha-Tocopherol results in increased expression of ACVRL1 mRNA CTD PMID:16908007 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Agt angiotensinogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein]; alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP alpha-Tocopherol results in increased expression of AKR1B1 mRNA CTD PMID:16908007 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of AKT1 protein]
CTD PMID:19351882 PMID:22343715 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Alb albumin multiple interactions EXP alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]] CTD PMID:17429802 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ano6 anoctamin 6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of ANO6 mRNA] CTD PMID:27886375 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA]
alpha-Tocopherol results in decreased expression of APEX2 mRNA
CTD PMID:26332274 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
decreases activity
ISO
EXP
alpha-Tocopherol results in decreased expression of APOA1 mRNA; alpha-Tocopherol results in decreased expression of APOA1 protein
alpha-Tocopherol results in decreased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apob apolipoprotein B multiple interactions ISO alpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper] CTD PMID:11368321 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] CTD PMID:12684028 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of ATF2 protein] CTD PMID:14645110 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP alpha-Tocopherol results in increased expression of BAD mRNA CTD PMID:26332274 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in increased expression of BAX protein]
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein]
alpha-Tocopherol results in increased expression of BAX mRNA
CTD PMID:11805214 PMID:26332274 PMID:32134168 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Endosulfan results in decreased activity of BCHE protein] CTD PMID:24299906 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; TNFRSF10B mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]
alpha-Tocopherol analog results in decreased expression of BCL2 mRNA; alpha-Tocopherol analog results in decreased expression of BCL2 protein
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of BCL2 protein]
CTD PMID:11805214 PMID:16005924 PMID:16135673 PMID:20686688 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP alpha-Tocopherol results in decreased expression of BCL2L1 protein CTD PMID:18942769 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased expression of BDNF protein] CTD PMID:30776390 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Canx calnexin affects localization
increases expression
EXP alpha-Tocopherol affects the localization of CANX protein
alpha-Tocopherol results in increased expression of CANX mRNA; alpha-Tocopherol results in increased expression of CANX protein
CTD PMID:16908007 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
ISO
EXP
[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein; [alpha-Tocopherol co-treated with Tretinoin] results in increased activity of CASP3 protein; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Acetaldehyde results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP3 protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased cleavage of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein]
alpha-Tocopherol results in decreased activity of CASP3 protein
CTD PMID:12450566 PMID:14599462 PMID:14722101 PMID:15095415 PMID:17618090 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]] CTD PMID:23042730 PMID:29129777 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases cleavage ISO alpha-Tocopherol analog results in increased cleavage of CASP8 protein CTD PMID:20686688 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO alpha-Tocopherol analog results in increased cleavage of CASP9 protein
alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]
alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP9 protein
CTD PMID:20686688 PMID:21869839 PMID:31712109 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases activity
increases expression
EXP
ISO
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [Copper Sulfate results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
alpha-Tocopherol results in increased activity of CAT protein
alpha-Tocopherol results in increased expression of CAT protein
alpha-Tocopherol results in increased expression of CAT mRNA; alpha-Tocopherol results in increased expression of CAT protein
CTD PMID:9306888 PMID:16979807 PMID:18547560 PMID:19083475 PMID:19464315 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA] CTD PMID:27257344 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD PMID:19735175 PMID:24333275 PMID:26332274 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA] CTD PMID:26332274 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA] CTD PMID:26332274 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd36 CD36 molecule affects expression
multiple interactions
EXP alpha-Tocopherol affects the expression of CD36 mRNA
alpha-Tocopherol inhibits the reaction [[troglitazone co-treated with Ethanol] results in increased expression of CD36 protein]
CTD PMID:16407258 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]
alpha-Tocopherol results in decreased expression of CDKN1A mRNA
CTD PMID:26332274 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO alpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein] CTD PMID:20363832 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] CTD PMID:25891525 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of CLCN3 mRNA] CTD PMID:27886375 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Cldn2 claudin 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Potassium Dichromate affects the localization of CLDN2 protein] CTD PMID:19766176 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CPT1A mRNA]; alpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA]
alpha-Tocopherol results in increased expression of CPT1A mRNA
CTD PMID:17936189 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 mRNA; [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 protein CTD PMID:15225641 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of CREB1 protein] CTD PMID:30776390 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crp C-reactive protein multiple interactions ISO [alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of CRP protein CTD PMID:18191645 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cryaa crystallin, alpha A increases expression EXP alpha-Tocopherol results in increased expression of CRYAA mRNA CTD PMID:16908007 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Ctsd cathepsin D increases expression EXP alpha-Tocopherol results in increased expression of CTSD protein CTD PMID:18942769 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA] CTD PMID:24333275 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA] CTD PMID:24333275 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP alpha-Tocopherol results in increased expression of CYP1A1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA]; alpha-Tocopherol results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:15665910 PMID:22389237 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
multiple interactions
EXP
ISO
alpha-Tocopherol results in increased activity of CYP1A2 protein
alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]
CTD PMID:15665910 PMID:26102010 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO alpha-Tocopherol results in decreased expression of CYP2B10 mRNA CTD PMID:26102010 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression ISO alpha-Tocopherol results in decreased expression of CYP2B9 mRNA CTD PMID:26102010 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein] CTD PMID:26102010
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
multiple interactions
EXP
ISO
alpha-Tocopherol results in increased expression of CYP2E1 mRNA
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]
CTD PMID:26332274 PMID:27919644 PMID:28062356 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
EXP
ISO
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]
alpha-Tocopherol results in increased expression of CYP3A4 mRNA
alpha-Tocopherol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CYP3A4 mRNA]; Galactosamine inhibits the reaction [alpha-Tocopherol results in increased expression of CYP3A4 mRNA]
CTD PMID:17936189 PMID:27919644 PMID:31102695 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions
ISO alpha-Tocopherol results in increased expression of CYP3A13 mRNA; alpha-Tocopherol results in increased expression of CYP3A13 protein
alpha-Tocopherol inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]
CTD PMID:26102010 PMID:31102695 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]
alpha-Tocopherol analog results in increased expression of DDIT3 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased expression of DDIT3 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased expression of DDIT3 protein]
CTD PMID:20459685 PMID:20686688 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects localization ISO alpha-Tocopherol affects the localization of DIABLO protein CTD PMID:15582575 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation
multiple interactions
ISO alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein]
CTD PMID:20686688 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Faslg Fas ligand increases expression EXP alpha-Tocopherol results in increased expression of FASLG mRNA CTD PMID:26332274 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fbl fibrillarin decreases expression EXP alpha-Tocopherol deficiency results in decreased expression of FBL protein CTD PMID:15247049 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression EXP alpha-Tocopherol results in increased expression of FMO1 mRNA CTD PMID:16908007 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein] CTD PMID:9225831 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of FYN protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of FYN protein] CTD PMID:14572611 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP alpha-Tocopherol results in increased expression of GADD45A mRNA CTD PMID:26332274 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLC mRNA CTD PMID:24530478 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP
ISO
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA]
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA
CTD PMID:22389237 PMID:24530478 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP alpha-Tocopherol results in increased expression of GFAP protein CTD PMID:18942769 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP alpha-Tocopherol inhibits the reaction [beryllium nitrate results in increased activity of GPT protein] CTD PMID:17429802 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Sodium Selenite results in increased expression of GPX4 mRNA] CTD PMID:14642406 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein] CTD PMID:16979807 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP alpha-Tocopherol results in increased expression of GSTT1 protein CTD PMID:9855024 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gusb glucuronidase, beta multiple interactions ISO alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in decreased uptake of GUSB protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of GUSB protein] CTD PMID:19135433 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hal histidine ammonia lyase increases expression EXP alpha-Tocopherol results in increased expression of HAL mRNA CTD PMID:16908007 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:19595682 PMID:21535577 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
multiple interactions
ISO
EXP
alpha-Tocopherol affects the expression of HMOX1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein]; alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]
alpha-Tocopherol inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]
CTD PMID:8743975 PMID:12180188 PMID:22053912 PMID:22389237 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hp haptoglobin affects activity
multiple interactions
ISO alpha-Tocopherol affects the activity of HP protein polymorphism
Ascorbic Acid inhibits the reaction [alpha-Tocopherol affects the activity of HP protein polymorphism]
CTD PMID:19769483 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD17B3 mRNA] CTD PMID:32134168 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD3B2 mRNA] CTD PMID:32134168 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP alpha-Tocopherol results in increased expression of HSPA1B mRNA CTD PMID:16908007 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 protein] CTD PMID:22313677 PMID:25551565 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions EXP [alpha-Tocopherol co-treated with Lipopolysaccharides] results in increased expression of IFNG mRNA; alpha-Tocopherol results in decreased susceptibility to [IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] CTD PMID:16307444 PMID:24333275 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; alpha-Tocopherol promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
[alpha-Tocopherol co-treated with Lipopolysaccharides] results in increased expression of IL10 mRNA
CTD PMID:24333275 PMID:25551565 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein] CTD PMID:15025948 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of IL1B protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of IL1B protein]; alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of IL1B mRNA]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of IL1B mRNA]
CTD PMID:19135433 PMID:19735175 PMID:26332274 PMID:31712109 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of IL6 protein]
alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:15630180 PMID:24296301 PMID:32134168 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of JUN protein]
alpha-Tocopherol results in increased expression of JUN mRNA; alpha-Tocopherol results in increased expression of JUN protein
CTD PMID:14645110 PMID:19000923 PMID:20025956 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein] CTD PMID:12531891 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased activity of LCAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:19595682 PMID:21535577 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LCK protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LCK protein] CTD PMID:14572611 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:21322096 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:21322096 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LYN protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LYN protein] CTD PMID:14572611 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
affects activity
ISO
EXP
alpha-Tocopherol inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK1 protein]
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK1 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of MAPK1 protein]
[alpha-Tocopherol affects the activity of MAPK1 protein] which results in decreased susceptibility to Potassium Dichromate
CTD PMID:17011908 PMID:19766176 PMID:30776390 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein] CTD PMID:12684028 PMID:14645110 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
affects activity
ISO
EXP
alpha-Tocopherol inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK3 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK3 protein]
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of MAPK3 protein]
[alpha-Tocopherol affects the activity of MAPK3 protein] which results in decreased susceptibility to Potassium Dichromate
CTD PMID:14645110 PMID:17011908 PMID:19766176 PMID:30776390 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein] CTD PMID:12684028 PMID:14645110 PMID:20686688 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein]
CTD PMID:20686688 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mb myoglobin multiple interactions EXP alpha-Tocopherol inhibits the reaction [MB modified form results in decreased secretion of very low density lipoprotein triglyceride] CTD PMID:17478120 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mbp myelin basic protein multiple interactions ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased expression of MBP protein] CTD PMID:14645110 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase increases expression EXP alpha-Tocopherol results in increased expression of MGAT3 mRNA CTD PMID:16908007 NCBI chr 7:111,708,353...111,761,825
Ensembl chr 7:111,675,730...111,762,026
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA] CTD PMID:24333275 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of MYC protein] CTD PMID:16005924 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nefh neurofilament heavy chain increases expression EXP alpha-Tocopherol results in increased expression of NEFH protein modified form CTD PMID:18942769 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein]; [alpha-Tocopherol co-treated with Hydrogen Peroxide] affects the localization of NFE2L2 protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of NFE2L2 protein] CTD PMID:22389237 PMID:31412289 PMID:32134168 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases activity
EXP
ISO
alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of NFKB1 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of [NFKB1 protein binds to RELA protein]]
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]
alpha-Tocopherol results in increased activity of NFKB1 protein
CTD PMID:15025948 PMID:16135673 PMID:17936189 PMID:19083475 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein]; alpha-Tocopherol inhibits the reaction [DCD protein results in increased phosphorylation of NFKBIA protein]
[Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]
alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased phosphorylation of NFKBIA protein]
CTD PMID:16135673 PMID:17532611 PMID:25551565 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased expression of NOS2 protein]
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased expression of NOS2 mRNA]
CTD PMID:17936189 PMID:19135433 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO alpha-Tocopherol results in increased expression of NOS3 mRNA; alpha-Tocopherol results in increased expression of NOS3 protein CTD PMID:16949522 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO alpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA] CTD PMID:17936189 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP alpha-Tocopherol inhibits the reaction [sodium arsenite results in decreased activity of OGDH protein] CTD PMID:12915223 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO alpha-Tocopherol results in increased expression of ORM1 mRNA; alpha-Tocopherol results in increased expression of ORM1 protein CTD PMID:19000923 PMID:20025956 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Rotenone affects the localization of PARK7 protein] CTD PMID:16439141 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]
alpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]
CTD PMID:14645110 PMID:24448832 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pawr pro-apoptotic WT1 regulator multiple interactions EXP alpha-Tocopherol inhibits the reaction [Nerve Growth Factors deficiency results in increased expression of PAWR mRNA]; alpha-Tocopherol inhibits the reaction [Nerve Growth Factors deficiency results in increased expression of PAWR protein] CTD PMID:10428045 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pax3 paired box 3 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of PAX3 mRNA]
alpha-Tocopherol results in increased expression of PAX3 mRNA
CTD PMID:12739027 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP alpha-Tocopherol results in decreased expression of PCK1 mRNA CTD PMID:11597575 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] CTD PMID:18603805 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Plg plasminogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [Arsenic promotes the reaction [Humic Substances results in decreased activity of PLG protein]]; alpha-Tocopherol inhibits the reaction [Humic Substances results in decreased activity of PLG protein] CTD PMID:11419606 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Pltp phospholipid transfer protein decreases abundance ISO PLTP mutant form results in decreased abundance of alpha-Tocopherol CTD PMID:16675720 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of PPARA mRNA]
alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of PPARA mRNA]
alpha-Tocopherol results in increased expression of PPARA mRNA
CTD PMID:17936189 PMID:29065513 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
increases activity
ISO
EXP
alpha-Tocopherol results in increased expression of PPARG mRNA; alpha-Tocopherol results in increased expression of PPARG protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein]
alpha-Tocopherol results in increased activity of PPARG protein
CTD PMID:11752099 PMID:14521714 PMID:19083475 PMID:22389237 PMID:28062356 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP alpha-Tocopherol results in increased expression of PPIA mRNA CTD PMID:16908007 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein] CTD PMID:17532611 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
ISO
EXP
alpha-Tocopherol metabolite results in decreased activity of PTGS2 protein; alpha-Tocopherol results in decreased activity of PTGS2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein]
CTD PMID:15225597 PMID:22389237 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
multiple interactions
ISO
EXP
alpha-Tocopherol affects the localization of RELA protein
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]
alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of RELA protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:15025948 PMID:16135673 PMID:16882165 PMID:17936189 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of RPS6 protein] CTD PMID:22343715 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA protein; [Tretinoin co-treated with alpha-Tocopherol] results in decreased phosphorylation of RXRA protein CTD PMID:15225641 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sele selectin E multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of SELE protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:12566129 PMID:25551565 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 mRNA; [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 protein CTD PMID:24530478 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Smad4 SMAD family member 4 multiple interactions ISO SMAD4 results in decreased susceptibility to [Fluorouracil co-treated with alpha-Tocopherol] CTD PMID:20562578 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Snca synuclein alpha multiple interactions ISO alpha-Tocopherol inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:16439141 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
EXP
ISO
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of SOD1 protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein]
alpha-Tocopherol results in increased expression of SOD1 mRNA; alpha-Tocopherol results in increased expression of SOD1 protein
CTD PMID:19083475 PMID:20194575 PMID:21344382 PMID:22732938 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
increases expression
multiple interactions
EXP alpha-Tocopherol results in decreased expression of SOD2 protein
alpha-Tocopherol results in increased expression of SOD2 mRNA; alpha-Tocopherol results in increased expression of SOD2 protein
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased expression of and results in increased activity of SOD2 protein]
CTD PMID:16135673 PMID:18942769 PMID:20194575 PMID:22732938 PMID:23859036 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression EXP alpha-Tocopherol deficiency results in decreased expression of SRSF2 protein CTD PMID:15247049 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of STAR mRNA] CTD PMID:32134168 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP alpha-Tocopherol results in increased expression of STAT3 mRNA CTD PMID:16908007 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased activity of TERT protein] CTD PMID:20112180 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tgfa transforming growth factor alpha decreases response to substance EXP alpha-Tocopherol results in decreased susceptibility to TGFA protein CTD PMID:7593635 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]
alpha-Tocopherol results in decreased expression of TGFB1 mRNA
CTD PMID:9608545 PMID:14732287 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; alpha-Tocopherol inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:15790535 PMID:25891525 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects expression
decreases response to substance
decreases expression
ISO
EXP
[alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of TNF protein; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; alpha-Tocopherol promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased secretion of TNF protein]
alpha-Tocopherol affects the expression of TNF protein
alpha-Tocopherol results in decreased susceptibility to TNF protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of TNF mRNA]
alpha-Tocopherol results in decreased expression of TNF protein
CTD PMID:10588948 PMID:11805214 PMID:12195823 PMID:15025948 PMID:15630180 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 mRNA]; alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 protein] CTD PMID:12126965 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of TXN1 protein] CTD PMID:21344382 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of VCAM1 protein]; alpha-Tocopherol inhibits the reaction [Vehicle Emissions results in increased expression of VCAM1 protein] CTD PMID:12566129 PMID:22313677 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO alpha-Tocopherol analog results in increased expression of XBP1 mRNA CTD PMID:20686688 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions EXP alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] CTD PMID:26332274 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
alpha-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, alpha results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO tocotrienol, alpha inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; tocotrienol, alpha inhibits the reaction [CYP3A4 protein results in increased oxidation of Lithocholic Acid]
tocotrienol, alpha results in increased expression of CYP3A4
CTD PMID:15269186 PMID:31102695 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects response to substance
multiple interactions
ISO CYP3A5 gene polymorphism affects the susceptibility to tocotrienol, alpha
tocotrienol, alpha inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; tocotrienol, alpha inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]
CTD PMID:31102695 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha] CTD PMID:15668500 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, alpha binds to and results in increased activity of NR1I2 protein; tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, alpha results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:88,801,344...88,808,465 JBrowse link
beta-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP
ISO
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]
beta-Tocopherol affects the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; beta-Tocopherol affects the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]
CTD PMID:12450566 PMID:22389237 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein] CTD PMID:22389237 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein] CTD PMID:22389237 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein] CTD PMID:22389237 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein] CTD PMID:22389237 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 9:88,801,344...88,808,465 JBrowse link
beta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, beta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO tocotrienol, beta results in increased expression of CYP3A4 CTD PMID:15269186 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, beta binds to and results in increased activity of NR1I2 protein; tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, beta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:88,801,344...88,808,465 JBrowse link
delta-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein] CTD PMID:22389237 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Tretinoin co-treated with delta-tocopherol] results in increased expression of CRABP2 mRNA CTD PMID:15225641 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein] CTD PMID:22389237 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein] CTD PMID:22389237 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein] CTD PMID:22389237 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein] CTD PMID:22389237 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 9:88,801,344...88,808,465 JBrowse link
delta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, delta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of ABCC1 mRNA]
tocotrienol, delta results in increased expression of ABCC1 mRNA
CTD PMID:22185406 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 decreases expression ISO tocotrienol, delta results in decreased expression of ABCD2 mRNA CTD PMID:22185406 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
G Actl6b actin-like 6B increases expression ISO tocotrienol, delta results in increased expression of ACTL6B mRNA CTD PMID:22185406 NCBI chr12:19,124,887...19,141,419
Ensembl chr12:19,124,916...19,141,376
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
increases expression
ISO tocotrienol, delta promotes the reaction [Lipopolysaccharides results in increased expression of ATP2A2 mRNA]
tocotrienol, delta results in increased expression of ATP2A2 mRNA
CTD PMID:22185406 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO tocotrienol, delta results in decreased expression of CCND1 protein CTD PMID:21453743 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CCND2 mRNA]
tocotrienol, delta results in increased expression of CCND2 mRNA
CTD PMID:22185406 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd40 CD40 molecule multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA]
tocotrienol, delta results in increased expression of CD40 mRNA
CTD PMID:22185406 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd69 Cd69 molecule multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 mRNA]
tocotrienol, delta results in increased expression of CD69 mRNA
CTD PMID:22185406 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cox7b2 cytochrome c oxidase subunit 7B2 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of COX7B2 mRNA]
tocotrienol, delta results in decreased expression of COX7B2 mRNA
CTD PMID:22185406 NCBI chr14:36,693,096...36,805,323
Ensembl chr14:36,693,105...36,805,523
JBrowse link
G Crp C-reactive protein multiple interactions ISO [resveratrol co-treated with pterostilbene co-treated with Quercetin co-treated with tocotrienol, delta co-treated with Niacin] results in decreased expression of CRP protein CTD PMID:24319627 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO tocotrienol, delta results in decreased expression of CTNNB1 protein CTD PMID:21453743 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; tocotrienol, delta inhibits the reaction [CYP3A4 protein results in increased oxidation of Lithocholic Acid]
tocotrienol, delta results in increased expression of CYP3A4
CTD PMID:15269186 PMID:31102695 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
affects response to substance
ISO tocotrienol, delta inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; tocotrienol, delta inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]
CYP3A5 gene polymorphism affects the susceptibility to tocotrienol, delta
CTD PMID:31102695 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Gimap1 GTPase, IMAP family member 1 multiple interactions
decreases expression
ISO tocotrienol, delta promotes the reaction [Lipopolysaccharides results in decreased expression of GIMAP1 mRNA]
tocotrienol, delta results in decreased expression of GIMAP1 mRNA
CTD PMID:22185406 NCBI chr 4:77,687,581...77,691,468
Ensembl chr 4:77,682,171...77,691,866
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of ICAM1 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]
CTD PMID:22185406 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO tocotrienol, delta inhibits the reaction [[IFNB1 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:22185406 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifng interferon gamma multiple interactions ISO tocotrienol, delta inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:22185406 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of IFNGR1 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of IFNGR1 mRNA]
CTD PMID:22185406 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Il12b interleukin 12B decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of IL12B mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
CTD PMID:22185406 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO tocotrienol, delta results in increased expression of IL1A mRNA CTD PMID:22185406 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
tocotrienol, delta results in increased expression of IL1B mRNA
CTD PMID:22185406 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression
multiple interactions
ISO tocotrienol, delta results in increased expression of IL1RN mRNA
tocotrienol, delta promotes the reaction [Lipopolysaccharides results in increased expression of IL1RN mRNA]
CTD PMID:22185406 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO tocotrienol, delta results in increased expression of IL6 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:22185406 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO tocotrienol, delta results in decreased expression of JUN protein CTD PMID:21453743 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO tocotrienol, delta results in decreased expression of MMP7 protein CTD PMID:21453743 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Lipopolysaccharides inhibits the reaction [tocotrienol, delta results in increased expression of NOS2]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:21356098 PMID:22185406 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, delta binds to and results in increased activity of NR1I2 protein; tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PHKA2 mRNA]
tocotrienol, delta results in increased expression of PHKA2 mRNA
CTD PMID:22185406 NCBI chr  X:34,170,959...34,293,498 JBrowse link
G Psmb2 proteasome 20S subunit beta 2 decreases expression ISO tocotrienol, delta results in decreased expression of PSMB2 mRNA CTD PMID:22185406 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
JBrowse link
G Ptbp2 polypyrimidine tract binding protein 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA]
tocotrienol, delta results in increased expression of PTBP2 mRNA
CTD PMID:22185406 NCBI chr 2:207,812,659...207,874,019
Ensembl chr 2:207,812,920...207,873,506
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of RASGRP1 mRNA]
tocotrienol, delta results in increased expression of RASGRP1 mRNA
CTD PMID:22185406 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of RASGRP3 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of RASGRP3 mRNA]
CTD PMID:22185406 NCBI chr 6:19,895,366...19,993,945
Ensembl chr 6:19,895,390...19,958,578
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]
tocotrienol, delta results in decreased expression of SOCS3 mRNA
CTD PMID:22185406 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO Lipopolysaccharides inhibits the reaction [tocotrienol, delta results in increased expression of TNF]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
tocotrienol, delta results in decreased expression of TNF mRNA
CTD PMID:21356098 PMID:22185406 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnp1 transition protein 1 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of TNP1 mRNA]
tocotrienol, delta results in decreased expression of TNP1 mRNA
CTD PMID:22185406 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of TRAF1 mRNA]
tocotrienol, delta results in increased expression of TRAF1 mRNA
CTD PMID:22185406 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA]
tocotrienol, delta results in decreased expression of UBE2D2A mRNA
CTD PMID:22185406 NCBI chr18:27,364,665...27,405,589
Ensembl chr18:27,364,303...27,406,181
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, delta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]
tocotrienol, delta results in decreased expression of VCAM1 mRNA
CTD PMID:22185406 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Wnt1 Wnt family member 1 decreases expression ISO tocotrienol, delta results in decreased expression of WNT1 protein CTD PMID:21453743 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
gamma-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO Tocopherols results in decreased activity of ABCC1 protein
Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]
CTD PMID:15617835 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Alb albumin multiple interactions EXP gamma-Tocopherol inhibits the reaction [ALB protein results in increased expression of MUC5AC mRNA] CTD PMID:19389874 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G App amyloid beta precursor protein decreases abundance
multiple interactions
EXP APP protein modified form results in decreased abundance of Tocopherols
resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Tocopherols]
CTD PMID:25654502 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor decreases expression
decreases activity
ISO [Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of AR mRNA; Tocopherols results in decreased expression of AR protein
Tocopherols results in decreased activity of AR protein
CTD PMID:12032296 PMID:16302272 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Tocopherols results in increased expression of ARF3 mRNA CTD PMID:17654050 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Tocopherols results in increased expression of ASPM mRNA CTD PMID:17056531 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Tocopherols results in increased expression of ATP1A2 mRNA CTD PMID:17654050 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Tocopherols results in increased expression of ATP1B2 mRNA CTD PMID:17654050 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Aurka aurora kinase A increases expression ISO Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance
multiple interactions
increases expression
ISO BAX protein results in increased susceptibility to Tocopherols
[Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA
gamma-Tocopherol results in increased expression of BAX mRNA
CTD PMID:16001965 PMID:31587439 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases expression
decreases response to substance
ISO Tocopherols results in increased expression of BCL2 mRNA; Tocopherols results in increased expression of BCL2 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA
gamma-Tocopherol results in decreased expression of BCL2 mRNA
BCL2 protein results in decreased susceptibility to Tocopherols
CTD PMID:8970189 PMID:16001965 PMID:31587439 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases response to substance ISO BCL2L1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Tocopherols results in increased expression of BIRC5 mRNA CTD PMID:17056531 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO Tocopherols results in increased expression of CAMK2G mRNA CTD PMID:17654050 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased activity of CASP3 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]
thermozymocidin inhibits the reaction [gamma-Tocopherol results in increased activity of CASP3 protein]
CTD PMID:15596715 PMID:22389237 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO gamma-Tocopherol results in increased activity of CASP9 protein CTD PMID:15596715 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression ISO gamma-Tocopherol results in increased expression of CAT protein CTD PMID:19115203 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Tocopherols results in increased expression of CCNB2 mRNA CTD PMID:17056531 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO gamma-Tocopherol results in decreased expression of CCND1 mRNA; gamma-Tocopherol results in decreased expression of CCND1 protein; Tocopherols results in decreased expression of CCND1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA
CTD PMID:12368234 PMID:12504091 PMID:31587439 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions
ISO gamma-Tocopherol results in decreased expression of CCNE1 mRNA; gamma-Tocopherol results in decreased expression of CCNE1 protein; Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA
CTD PMID:12368234 PMID:12504091 PMID:31587439 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Tocopherols results in increased expression of CDC6 mRNA CTD PMID:17056531 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO Tocopherols results in increased expression of CDK1 mRNA CTD PMID:17056531 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein CTD PMID:12504091 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Tocopherols results in increased expression of CDK5R1 mRNA CTD PMID:17654050 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO gamma-Tocopherol results in decreased expression of CDKN1A protein CTD PMID:12368234 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO gamma-Tocopherol results in decreased expression of CDKN1B protein CTD PMID:12368234 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO gamma-Tocopherol results in decreased expression of CDKN2A protein CTD PMID:12368234 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Tocopherols results in increased expression of CLEC4E mRNA CTD PMID:17056531 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Cplx1 complexin 1 increases expression ISO Tocopherols results in increased expression of CPLX1 mRNA CTD PMID:17654050 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Cplx2 complexin 2 increases expression ISO Tocopherols results in increased expression of CPLX2 mRNA CTD PMID:17654050 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Tretinoin co-treated with gamma-Tocopherol] results in increased expression of CRABP2 mRNA CTD PMID:15225641 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Crp C-reactive protein multiple interactions ISO [alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of CRP protein CTD PMID:18191645 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Tocopherols results in increased expression of CSF1R mRNA CTD PMID:17056531 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO Tocopherols results in increased expression of CSRP2 mRNA CTD PMID:17056531 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Tocopherols results in increased expression of DNAJC5 mRNA CTD PMID:17654050 NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Egr1 early growth response 1 decreases activity ISO Tocopherols results in decreased activity of EGR1 protein CTD PMID:15878867 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia increases expression ISO Tocopherols results in increased expression of FCER1A mRNA CTD PMID:17056531 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase increases expression ISO Tocopherols results in increased expression of FES mRNA CTD PMID:17056531 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Tocopherols results in decreased expression of FGF1 mRNA CTD PMID:15878867 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Tocopherols results in decreased expression of FGF2 mRNA CTD PMID:15878867 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Tocopherols results in decreased expression of FGFR1 mRNA CTD PMID:15144885 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 increases expression ISO Tocopherols results in increased expression of FKBP9 mRNA CTD PMID:17056531 NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of FOS mRNA; Tocopherols results in increased expression of FOS protein CTD PMID:8970189 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Tocopherols results in increased expression of GRIA2 mRNA CTD PMID:17654050 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of GSTM1 mRNA; gamma-Tocopherol results in increased expression of GSTM1 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]
CTD PMID:19115203 PMID:22389237 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases activity ISO Tocopherols results in decreased activity of GSTO1 protein CTD PMID:16781109 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Tocopherols results in increased expression of HASPIN mRNA CTD PMID:17056531 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of HMOX1 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein]
CTD PMID:19115203 PMID:22389237 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of JUN mRNA; Tocopherols results in increased expression of JUN protein CTD PMID:8970189 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Tocopherols results in increased expression of KIF20A mRNA CTD PMID:17056531 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif4a kinesin family member 4A increases expression ISO Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 NCBI chr  X:65,721,724...65,824,151
Ensembl chr  X:65,721,779...65,824,139
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases response to substance ISO MCL1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP gamma-Tocopherol inhibits the reaction [ALB protein results in increased expression of MUC5AC mRNA] CTD PMID:19389874 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
decreases activity
ISO Tocopherols results in decreased expression of MYC mRNA
Tocopherols results in decreased activity of MYC protein
CTD PMID:8970189 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Napb NSF attachment protein beta increases expression ISO Tocopherols results in increased expression of NAPB mRNA CTD PMID:17654050 NCBI chr 3:136,132,248...136,179,225
Ensembl chr 3:136,133,428...136,179,345
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of NFE2L2 mRNA; gamma-Tocopherol results in increased expression of NFE2L2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein]
CTD PMID:19115203 PMID:22389237 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Tocopherols results in increased expression of NSF mRNA CTD PMID:17654050 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression
EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein]
Tocopherols results in decreased expression of PCNA
CTD PMID:17927505 PMID:22389237 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of PPARG mRNA; gamma-Tocopherol results in increased expression of PPARG protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein]
CTD PMID:14521714 PMID:22389237 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Tocopherols results in increased expression of PPP3CA mRNA CTD PMID:17654050 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prtn3 proteinase 3 increases expression ISO Tocopherols results in increased expression of PRTN3 mRNA CTD PMID:17056531 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
ISO
EXP
gamma-Tocopherol results in decreased activity of PTGS2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein]
CTD PMID:15225597 PMID:22389237 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression ISO Tocopherols results in increased expression of PTPRO mRNA CTD PMID:17056531 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB11B mRNA CTD PMID:17654050 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593
JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB3A mRNA CTD PMID:17654050 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336
JBrowse link
G Rab6b RAB6B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB6B mRNA CTD PMID:17654050 NCBI chr 8:103,695,328...103,764,023
Ensembl chr 8:103,695,631...103,805,732
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression ISO Tocopherols results in increased expression of RRM1 mRNA CTD PMID:17056531 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Snca synuclein alpha increases expression ISO Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sncb synuclein, beta increases expression ISO Tocopherols results in increased expression of SNCB mRNA CTD PMID:17654050 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO gamma-Tocopherol results in increased expression of SOD1 protein CTD PMID:19115203 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Stx1a syntaxin 1A increases expression ISO Tocopherols results in increased expression of STX1A mRNA CTD PMID:17654050 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression ISO Tocopherols results in increased expression of STXBP1 mRNA CTD PMID:17654050 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Sv2a synaptic vesicle glycoprotein 2a increases expression ISO Tocopherols results in increased expression of SV2A mRNA CTD PMID:17654050 NCBI chr 2:183,741,455...183,757,290
Ensembl chr 2:183,741,547...183,756,927
JBrowse link
G Syn1 synapsin I increases expression ISO Tocopherols results in increased expression of SYN1 mRNA CTD PMID:17654050 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Syn2 synapsin II increases expression ISO Tocopherols results in increased expression of SYN2 mRNA CTD PMID:17654050 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syngr1 synaptogyrin 1 increases expression ISO Tocopherols results in increased expression of SYNGR1 mRNA CTD PMID:17654050 NCBI chr 7:111,635,911...111,659,341
Ensembl chr 7:111,635,918...111,659,341
JBrowse link
G Syp synaptophysin increases expression ISO Tocopherols results in increased expression of SYP mRNA CTD PMID:17654050 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Syt11 synaptotagmin 11 increases expression ISO Tocopherols results in increased expression of SYT11 mRNA CTD PMID:17654050 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Syt13 synaptotagmin 13 increases expression ISO Tocopherols results in increased expression of SYT13 mRNA CTD PMID:17654050 NCBI chr 3:78,877,200...78,915,375
Ensembl chr 3:78,877,114...78,917,392
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
[alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of TNF protein
Tocopherols inhibits the reaction [TNF protein results in decreased export of Potassium]
CTD PMID:17337591 PMID:18191645 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Tocopherols results in increased expression of TNFAIP2 mRNA CTD PMID:17056531 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tp53 tumor protein p53 increases activity ISO Tocopherols results in increased activity of TP53 protein CTD PMID:15883045 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 increases expression ISO Tocopherols results in increased expression of TTC3 mRNA CTD PMID:17654050 NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of UGT1A1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA]
CTD PMID:19115203 PMID:22389237 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Vamp2 vesicle-associated membrane protein 2 increases expression ISO Tocopherols results in increased expression of VAMP2 mRNA CTD PMID:17654050 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vdr vitamin D receptor increases expression ISO Tocopherols results in increased expression of VDR mRNA CTD PMID:12032296 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]
Tocopherols results in decreased activity of ABCC1 protein
CTD PMID:15617835 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases abundance
EXP resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Tocopherols] CTD PMID:25654502 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor decreases activity
decreases expression
ISO Tocopherols results in decreased activity of AR protein
[Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of AR mRNA; Tocopherols results in decreased expression of AR protein
CTD PMID:12032296 PMID:16302272 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Tocopherols results in increased expression of ARF3 mRNA CTD PMID:17654050 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Tocopherols results in increased expression of ASPM mRNA CTD PMID:17056531 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Tocopherols results in increased expression of ATP1A2 mRNA CTD PMID:17654050 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Tocopherols results in increased expression of ATP1B2 mRNA CTD PMID:17654050 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Aurka aurora kinase A increases expression ISO Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance ISO BAX protein results in increased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
increases expression
ISO BCL2 protein results in decreased susceptibility to Tocopherols
Tocopherols results in increased expression of BCL2 mRNA; Tocopherols results in increased expression of BCL2 protein
CTD PMID:8970189 PMID:16001965 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases response to substance ISO BCL2L1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Tocopherols results in increased expression of BIRC5 mRNA CTD PMID:17056531 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO Tocopherols results in increased expression of CAMK2G mRNA CTD PMID:17654050 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Tocopherols results in increased expression of CCNB2 mRNA CTD PMID:17056531 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Tocopherols results in decreased expression of CCND1 protein CTD PMID:12504091 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 protein CTD PMID:12504091 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Tocopherols results in increased expression of CDC6 mRNA CTD PMID:17056531 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO Tocopherols results in increased expression of CDK1 mRNA CTD PMID:17056531 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein CTD PMID:12504091 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Tocopherols results in increased expression of CDK5R1 mRNA CTD PMID:17654050 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Tocopherols results in increased expression of CLEC4E mRNA CTD PMID:17056531 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Cplx1 complexin 1 increases expression ISO Tocopherols results in increased expression of CPLX1 mRNA CTD PMID:17654050 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Cplx2 complexin 2 increases expression ISO Tocopherols results in increased expression of CPLX2 mRNA CTD PMID:17654050 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Tocopherols results in increased expression of CSF1R mRNA CTD PMID:17056531 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO Tocopherols results in increased expression of CSRP2 mRNA CTD PMID:17056531 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Tocopherols results in increased expression of DNAJC5 mRNA CTD PMID:17654050 NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Egr1 early growth response 1 decreases activity ISO Tocopherols results in decreased activity of EGR1 protein CTD PMID:15878867 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia increases expression ISO Tocopherols results in increased expression of FCER1A mRNA CTD PMID:17056531 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase increases expression ISO Tocopherols results in increased expression of FES mRNA CTD PMID:17056531 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Tocopherols results in decreased expression of FGF1 mRNA CTD PMID:15878867 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Tocopherols results in decreased expression of FGF2 mRNA CTD PMID:15878867 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Tocopherols results in decreased expression of FGFR1 mRNA CTD PMID:15144885 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 increases expression ISO Tocopherols results in increased expression of FKBP9 mRNA CTD PMID:17056531 NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of FOS mRNA; Tocopherols results in increased expression of FOS protein CTD PMID:8970189 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Tocopherols results in increased expression of GRIA2 mRNA CTD PMID:17654050 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases activity ISO Tocopherols results in decreased activity of GSTO1 protein CTD PMID:16781109 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Tocopherols results in increased expression of HASPIN mRNA CTD PMID:17056531 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of JUN mRNA; Tocopherols results in increased expression of JUN protein CTD PMID:8970189 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Tocopherols results in increased expression of KIF20A mRNA CTD PMID:17056531 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif4a kinesin family member 4A increases expression ISO Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 NCBI chr  X:65,721,724...65,824,151
Ensembl chr  X:65,721,779...65,824,139
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases response to substance ISO MCL1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases activity
decreases expression
ISO Tocopherols results in decreased activity of MYC protein
Tocopherols results in decreased expression of MYC mRNA
CTD PMID:8970189 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Napb NSF attachment protein beta increases expression ISO Tocopherols results in increased expression of NAPB mRNA CTD PMID:17654050 NCBI chr 3:136,132,248...136,179,225
Ensembl chr 3:136,133,428...136,179,345
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Tocopherols results in increased expression of NSF mRNA CTD PMID:17654050 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP Tocopherols results in decreased expression of PCNA CTD PMID:17927505 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Tocopherols results in increased expression of PPP3CA mRNA CTD PMID:17654050 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prtn3 proteinase 3 increases expression ISO Tocopherols results in increased expression of PRTN3 mRNA CTD PMID:17056531 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression ISO Tocopherols results in increased expression of PTPRO mRNA CTD PMID:17056531 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB11B mRNA CTD PMID:17654050 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593
JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB3A mRNA CTD PMID:17654050 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336
JBrowse link
G Rab6b RAB6B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB6B mRNA CTD PMID:17654050 NCBI chr 8:103,695,328...103,764,023
Ensembl chr 8:103,695,631...103,805,732
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression ISO Tocopherols results in increased expression of RRM1 mRNA CTD PMID:17056531 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Snca synuclein alpha increases expression ISO Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sncb synuclein, beta increases expression ISO Tocopherols results in increased expression of SNCB mRNA CTD PMID:17654050 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
JBrowse link
G Stx1a syntaxin 1A increases expression ISO Tocopherols results in increased expression of STX1A mRNA CTD PMID:17654050 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression ISO Tocopherols results in increased expression of STXBP1 mRNA CTD PMID:17654050 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Sv2a synaptic vesicle glycoprotein 2a increases expression ISO Tocopherols results in increased expression of SV2A mRNA CTD PMID:17654050 NCBI chr 2:183,741,455...183,757,290
Ensembl chr 2:183,741,547...183,756,927
JBrowse link
G Syn1 synapsin I increases expression ISO Tocopherols results in increased expression of SYN1 mRNA CTD PMID:17654050 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Syn2 synapsin II increases expression ISO Tocopherols results in increased expression of SYN2 mRNA CTD PMID:17654050 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syngr1 synaptogyrin 1 increases expression ISO Tocopherols results in increased expression of SYNGR1 mRNA CTD PMID:17654050 NCBI chr 7:111,635,911...111,659,341
Ensembl chr 7:111,635,918...111,659,341
JBrowse link
G Syp synaptophysin increases expression ISO Tocopherols results in increased expression of SYP mRNA CTD PMID:17654050 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Syt11 synaptotagmin 11 increases expression ISO Tocopherols results in increased expression of SYT11 mRNA CTD PMID:17654050 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Syt13 synaptotagmin 13 increases expression ISO Tocopherols results in increased expression of SYT13 mRNA CTD PMID:17654050 NCBI chr 3:78,877,200...78,915,375
Ensembl chr 3:78,877,114...78,917,392
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Tocopherols inhibits the reaction [TNF protein results in decreased export of Potassium] CTD PMID:17337591 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Tocopherols results in increased expression of TNFAIP2 mRNA CTD PMID:17056531 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tp53 tumor protein p53 increases activity ISO Tocopherols results in increased activity of TP53 protein CTD PMID:15883045 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 increases expression ISO Tocopherols results in increased expression of TTC3 mRNA CTD PMID:17654050 NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 increases expression ISO Tocopherols results in increased expression of VAMP2 mRNA CTD PMID:17654050 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vdr vitamin D receptor increases expression ISO Tocopherols results in increased expression of VDR mRNA CTD PMID:12032296 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
Tocophersolan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with Resveratrol] results in decreased expression of ABCB1 protein CTD PMID:25392124 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
vitamin E term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aamp angio-associated, migratory cell protein increases expression ISO Vitamin E results in increased expression of AAMP mRNA CTD PMID:19244175 NCBI chr 9:75,863,382...75,869,188
Ensembl chr 9:75,863,389...75,868,547
JBrowse link
G Aass aminoadipate-semialdehyde synthase multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNA
Vitamin E results in decreased expression of AASS mRNA
CTD PMID:19244175 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA CTD PMID:11444866 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abhd14a abhydrolase domain containing 14A decreases expression ISO Vitamin E results in decreased expression of ABHD14A mRNA CTD PMID:19244175 NCBI chr 8:107,079,139...107,089,004
Ensembl chr 8:107,079,144...107,086,985
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression
increases expression
ISO Vitamin E results in decreased expression of ABHD2 mRNA
Vitamin E results in increased expression of ABHD2 mRNA
CTD PMID:19244175 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Vitamin E results in increased expression of ABHD4 mRNA CTD PMID:19244175 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression ISO Vitamin E results in increased expression of ACAA2 mRNA CTD PMID:19244175 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ACADS mRNA
Vitamin E results in increased expression of ACADS mRNA
CTD PMID:19244175 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
[Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]
CTD PMID:11814146 PMID:20663516 PMID:23619517 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Aco2 aconitase 2 increases expression ISO Vitamin E results in increased expression of ACO2 mRNA CTD PMID:19244175 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ACOT2 mRNA
Vitamin E results in increased expression of ACOT2 mRNA
CTD PMID:19244175 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acp1 acid phosphatase 1 decreases expression ISO Vitamin E results in decreased expression of ACP1 mRNA CTD PMID:19244175 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Vitamin E results in decreased expression of ACTA2 mRNA CTD PMID:19244175 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta increases expression ISO Vitamin E results in increased expression of ACTB mRNA CTD PMID:19244175 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actn4 actinin alpha 4 increases expression ISO Vitamin E results in increased expression of ACTN4 mRNA CTD PMID:19244175 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Actr1a actin related protein 1A increases expression ISO Vitamin E results in increased expression of ACTR1A mRNA CTD PMID:19244175 NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495
JBrowse link
G Actr1b actin related protein 1B increases expression ISO Vitamin E results in increased expression of ACTR1B mRNA CTD PMID:19244175 NCBI chr 9:38,928,819...38,938,483
Ensembl chr 9:38,929,912...38,938,507
JBrowse link
G Acvr2a activin A receptor type 2A decreases expression ISO Vitamin E results in decreased expression of ACVR2A mRNA CTD PMID:19244175 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression ISO Vitamin E results in decreased expression of ADAM17 mRNA CTD PMID:19244175 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression ISO Vitamin E results in decreased expression of ADAMTS5 mRNA CTD PMID:19244175 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
JBrowse link
G Adap1 ArfGAP with dual PH domains 1 increases expression ISO Vitamin E results in increased expression of ADAP1 mRNA CTD PMID:19244175 NCBI chr12:15,323,913...15,376,110
Ensembl chr12:15,324,209...15,380,831
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 decreases expression ISO Vitamin E results in decreased expression of ADARB1 mRNA CTD PMID:19244175 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
JBrowse link
G Adcy2 adenylate cyclase 2 multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of ADCY2 mRNA CTD PMID:19244175 NCBI chr 1:34,375,639...34,822,237
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression ISO Vitamin E results in increased expression of ADCY6 mRNA CTD PMID:19244175 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Add1 adducin 1 increases expression ISO Vitamin E results in increased expression of ADD1 mRNA CTD PMID:19244175 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Add3 adducin 3 decreases expression ISO Vitamin E results in decreased expression of ADD3 mRNA CTD PMID:19244175 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 increases expression ISO Vitamin E results in increased expression of ADGRB1 mRNA CTD PMID:19244175 NCBI chr 7:106,404,844...106,476,902
Ensembl chr 7:106,404,958...106,476,902
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression ISO Vitamin E results in decreased expression of ADH7 mRNA CTD PMID:19244175 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ mRNA]; Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein] CTD PMID:20404018 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adra2c adrenoceptor alpha 2C increases expression ISO Vitamin E results in increased expression of ADRA2C mRNA CTD PMID:19244175 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor increases expression ISO Vitamin E results in increased expression of ADRM1 mRNA CTD PMID:19244175 NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
JBrowse link
G Aebp1 AE binding protein 1 increases expression ISO Vitamin E results in increased expression of AEBP1 mRNA CTD PMID:19244175 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO Vitamin E results in increased expression of AEN mRNA CTD PMID:19244175 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 multiple interactions ISO [Selenium co-treated with Vitamin E] results in decreased expression of AGPAT2 mRNA CTD PMID:19244175 NCBI chr 3:9,416,842...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Agrn agrin decreases expression ISO Vitamin E results in decreased expression of AGRN mRNA CTD PMID:19244175 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 decreases expression ISO Vitamin E results in decreased expression of AGTPBP1 mRNA CTD PMID:19244175 NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Vitamin E results in increased expression of AHNAK mRNA CTD PMID:19244175 NCBI chr 1:205,882,223...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO Vitamin E results in increased expression of AHNAK2 mRNA CTD PMID:19244175 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Vitamin E results in decreased expression of AHR mRNA CTD PMID:19244175 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression ISO Vitamin E results in increased expression of AHSA1 mRNA CTD PMID:19244175 NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of AIMP1 mRNA
Vitamin E results in decreased expression of AIMP1 mRNA
CTD PMID:19244175 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Ak1 adenylate kinase 1 increases expression ISO Vitamin E results in increased expression of AK1 mRNA CTD PMID:19244175 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Ak3 adenylate kinase 3 multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of AK3 mRNA CTD PMID:19244175 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Akap13 A-kinase anchoring protein 13 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of AKAP13 mRNA
Vitamin E results in decreased expression of AKAP13 mRNA
CTD PMID:19244175 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akap2 A-kinase anchoring protein 2 increases expression
decreases expression
ISO Vitamin E results in increased expression of PALM2AKAP2 mRNA
Vitamin E results in decreased expression of PALM2AKAP2 mRNA
CTD PMID:19244175 NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO Vitamin E results in increased expression of AKR1B1 mRNA CTD PMID:19244175 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Vitamin E results in increased expression of AKR1C2 mRNA CTD PMID:19244175 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions
ISO
EXP
Vitamin E results in increased expression of AKT1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]
CTD PMID:19244175 PMID:21911000 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions EXP Vitamin E inhibits the reaction [lead acetate results in decreased activity of ALAD protein] CTD PMID:2604901 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alb albumin multiple interactions ISO
EXP
Vitamin E inhibits the reaction [Ethanol results in decreased expression of ALB protein]
[Quercetin co-treated with Vitamin E] inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]; Vitamin E inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]
Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]
CTD PMID:17927767 PMID:21086752 PMID:23348005 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Vitamin E results in decreased expression of ALDH6A1 mRNA CTD PMID:19244175 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Vitamin E results in increased expression of ALDOA mRNA CTD PMID:19244175 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase increases expression ISO Vitamin E results in increased expression of ALG3 mRNA CTD PMID:19244175 NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912
JBrowse link
G Alg9 ALG9, alpha-1,2-mannosyltransferase multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of ALG9 mRNA CTD PMID:19244175 NCBI chr 8:51,117,057...51,188,790
Ensembl chr 8:51,119,365...51,182,261
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase decreases expression ISO Vitamin E results in decreased expression of ALKBH1 mRNA CTD PMID:19244175 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity
multiple interactions
ISO
EXP
Vitamin E results in decreased activity of ALOX5 protein
[Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein
CTD PMID:11325678 PMID:12200813 PMID:22223226 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP Vitamin E inhibits the reaction [Doxorubicin results in decreased activity of ALPL protein] CTD PMID:32810592 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 increases expression ISO Vitamin E results in increased expression of AMBRA1 mRNA CTD PMID:19244175 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Anapc15 anaphase promoting complex subunit 15 increases expression ISO Vitamin E results in increased expression of ANAPC15 mRNA CTD PMID:19244175 NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145
JBrowse link
G Andpro androgen regulated protein decreases expression EXP Vitamin E results in decreased expression of ANDPRO mRNA CTD PMID:15084515 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966
JBrowse link
G Angpt1 angiopoietin 1 decreases expression ISO Vitamin E results in decreased expression of ANGPT1 mRNA CTD PMID:19244175 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Ank3 ankyrin 3 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNA
Vitamin E results in decreased expression of ANK3 mRNA
CTD PMID:19244175 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Ankrd12 ankyrin repeat domain 12 decreases expression ISO Vitamin E results in decreased expression of ANKRD12 mRNA CTD PMID:19244175 NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ANP32B mRNA
Vitamin E results in decreased expression of ANP32B mRNA
CTD PMID:19244175 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
JBrowse link
G Anxa6 annexin A6 increases expression ISO Vitamin E results in increased expression of ANXA6 mRNA CTD PMID:19244175 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
JBrowse link
G Ap1m2 adaptor related protein complex 1 subunit mu 2 increases expression ISO Vitamin E results in increased expression of AP1M2 mRNA CTD PMID:19244175 NCBI chr 8:19,838,579...19,856,560
Ensembl chr 8:19,838,580...19,856,482
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 increases expression ISO Vitamin E results in increased expression of AP2A2 mRNA CTD PMID:19244175 NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression ISO Vitamin E results in increased expression of AP2M1 mRNA CTD PMID:19244175 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 increases expression ISO Vitamin E results in increased expression of AP2S1 mRNA CTD PMID:19244175 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
JBrowse link
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 increases expression ISO Vitamin E results in increased expression of AP3S2 mRNA CTD PMID:19244175 NCBI chr 1:133,818,825...133,859,269
Ensembl chr 1:133,818,825...133,859,322
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 decreases expression ISO Vitamin E results in decreased expression of APBB2 mRNA CTD PMID:19244175 NCBI chr14:41,557,918...41,878,622 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Vitamin E results in increased expression of APEX1 mRNA CTD PMID:19244175 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 increases expression ISO Vitamin E results in increased expression of APLP2 mRNA CTD PMID:19244175 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Vitamin E results in increased expression of APOA1 protein CTD PMID:18458655 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; Vitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Vitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]] CTD PMID:17237316 PMID:17475462 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO Vitamin E inhibits the reaction [APOE mutant form results in increased abundance of 8,12-iso-isoprostane F2alpha-VI] CTD PMID:16303615 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apol3 apolipoprotein L, 3 increases expression ISO Vitamin E results in increased expression of APOL3 mRNA CTD PMID:19244175 NCBI chr 7:109,288,725...109,297,728
Ensembl chr 7:109,288,725...109,297,723
JBrowse link
G Apom apolipoprotein M increases expression ISO Vitamin E results in increased expression of APOM mRNA CTD PMID:19244175 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G App amyloid beta precursor protein decreases expression
multiple interactions
ISO
EXP
Vitamin E results in decreased expression of APP mRNA
Vitamin E inhibits the reaction [APP protein modified form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]
Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein]
CTD PMID:12039845 PMID:12117551 PMID:15223066 PMID:19244175 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of APPBP2 mRNA
Vitamin E results in increased expression of APPBP2 mRNA
CTD PMID:19244175 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Vitamin E results in increased expression of AQP1 mRNA CTD PMID:19244175 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression
multiple interactions
ISO Vitamin E results in increased expression of AQP3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AQP3 mRNA
CTD PMID:19244175 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP
ISO
Vitamin E inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein]
Vitamin E inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]
CTD PMID:20648640 PMID:30914277 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of ARAF mRNA CTD PMID:19244175 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Vitamin E results in increased expression of ARF3 mRNA CTD PMID:19244175 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
JBrowse link
G Arf5 ADP-ribosylation factor 5 increases expression ISO Vitamin E results in increased expression of ARF5 mRNA CTD PMID:19244175 NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441
JBrowse link
G Arhgap10 Rho GTPase activating protein 10 increases expression ISO Vitamin E results in increased expression of ARHGAP10 mRNA CTD PMID:19244175 NCBI chr19:30,448,572...30,710,315
Ensembl chr19:30,448,637...30,710,313
JBrowse link
G Arhgap8 Rho GTPase activating protein 8 increases expression ISO Vitamin E results in increased expression of ARHGAP8 mRNA CTD PMID:19244175 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Vitamin E results in increased expression of ARHGDIA mRNA CTD PMID:19244175 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 decreases expression ISO Vitamin E results in decreased expression of ARIH1 mRNA CTD PMID:19244175 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D increases expression ISO Vitamin E results in increased expression of ARL4D mRNA CTD PMID:19244175 NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 increases expression ISO Vitamin E results in increased expression of ARL6IP4 mRNA CTD PMID:19244175 NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression ISO Vitamin E results in increased expression of ARPC1A mRNA CTD PMID:19244175 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Vitamin E results in increased expression of ARPC4 mRNA CTD PMID:19244175 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 increases expression ISO Vitamin E results in increased expression of ASAP3 mRNA CTD PMID:19244175 NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ASB1 mRNA
Vitamin E results in increased expression of ASB1 mRNA
CTD PMID:19244175 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression ISO Vitamin E results in decreased expression of ASXL1 mRNA CTD PMID:19244175 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
JBrowse link
G Atf2 activating transcription factor 2 increases phosphorylation ISO Vitamin E results in increased phosphorylation of ATF2 protein CTD PMID:11522656 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf3 activating transcription factor 3 decreases expression ISO Vitamin E results in decreased expression of ATF3 mRNA CTD PMID:19244175 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf5 activating transcription factor 5 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ATF5 mRNA
Vitamin E results in increased expression of ATF5 mRNA
CTD PMID:19244175 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atg12 autophagy related 12 decreases expression ISO Vitamin E results in decreased expression of ATG12 mRNA CTD PMID:19244175 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atmin ATM interactor multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ATMIN mRNA
Vitamin E results in decreased expression of ATMIN mRNA
CTD PMID:19244175 NCBI chr19:44,996,506...45,013,606 JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression ISO Vitamin E results in increased expression of ATOX1 mRNA CTD PMID:19244175 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO Vitamin E results in increased expression of ATP5F1B mRNA CTD PMID:19244175 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Vitamin E results in decreased expression of ATP5F1C mRNA CTD PMID:19244175 NCBI chr17:68,423,927...68,446,169 JBrowse link
G Atp5me ATP synthase membrane subunit e decreases expression ISO Vitamin E results in decreased expression of ATP5ME mRNA CTD PMID:19244175 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 decreases expression ISO Vitamin E results in decreased expression of ATP6AP2 mRNA CTD PMID:19244175 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 increases expression ISO Vitamin E results in increased expression of ATP6V0D1 mRNA CTD PMID:19244175 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 decreases expression ISO Vitamin E results in decreased expression of ATP6V1C1 mRNA CTD PMID:19244175 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 decreases expression ISO Vitamin E results in decreased expression of ATP8B1 mRNA CTD PMID:19244175 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression
multiple interactions
ISO Vitamin E results in decreased expression of ATRX mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA
CTD PMID:19244175 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Vitamin E results in decreased expression of ATXN3 mRNA CTD PMID:19244175 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Atxn7 ataxin 7 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ATXN7 mRNA
Vitamin E results in decreased expression of ATXN7 mRNA
CTD PMID:19244175 NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 decreases expression ISO Vitamin E results in decreased expression of AUTS2 mRNA CTD PMID:19244175
G Axl Axl receptor tyrosine kinase decreases expression ISO Vitamin E results in decreased expression of AXL mRNA CTD PMID:19244175 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression EXP Vitamin E results in increased expression of BAAT mRNA CTD PMID:28923436 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 increases expression ISO Vitamin E results in increased expression of BABAM1 mRNA CTD PMID:19244175 NCBI chr16:18,068,830...18,074,938
Ensembl chr16:18,068,884...18,074,923
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO Vitamin E results in increased expression of BABAM2 mRNA CTD PMID:19244175 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO Vitamin E results in decreased expression of BAG5 mRNA CTD PMID:19244175 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Bag6 BAG cochaperone 6 increases expression ISO Vitamin E results in increased expression of BAG6 mRNA CTD PMID:19244175 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Banf1 BAF nuclear assembly factor 1 increases expression ISO Vitamin E results in increased expression of BANF1 mRNA CTD PMID:19244175 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188
JBrowse link
G Bap1 Brca1 associated protein 1 increases expression ISO Vitamin E results in increased expression of BAP1 mRNA CTD PMID:19244175 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression ISO Vitamin E results in decreased expression of BARD1 mRNA CTD PMID:19244175 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor increases expression ISO Vitamin E results in increased expression of BATF mRNA CTD PMID:19244175 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
ISO
EXP
Vitamin E inhibits the reaction [cinnamaldehyde results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of BAX protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased expression of BAX protein]
[Vitamin E co-treated with Folic Acid] affects the expression of BAX protein; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased expression of BAX protein]
Vitamin E affects the expression of BAX protein
Vitamin E results in increased expression of BAX protein
CTD PMID:11166918 PMID:15566391 PMID:16054126 PMID:16933212 PMID:22020378 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A decreases expression ISO Vitamin E results in decreased expression of BAZ1A mRNA CTD PMID:19244175 NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B increases expression ISO Vitamin E results in increased expression of BAZ1B mRNA CTD PMID:19244175 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
JBrowse link
G Bbx BBX high mobility group box domain containing multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of BBX mRNA
Vitamin E results in decreased expression of BBX mRNA
CTD PMID:19244175 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 increases expression ISO Vitamin E results in increased expression of BCAP31 mRNA CTD PMID:19244175 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein] CTD PMID:20663516 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO Vitamin E results in decreased expression of BCL11A mRNA CTD PMID:19244175 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
[Vitamin E co-treated with Curcumin] results in decreased expression of BCL2 protein; Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BCL2 protein]
Vitamin E results in increased expression of BCL2 mRNA
[Vitamin E co-treated with Folic Acid] affects the expression of BCL2 protein; Vitamin E inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased expression of BCL2 protein]
CTD PMID:15566391 PMID:16933212 PMID:22020378 PMID:27353299 PMID:30935902 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
EXP
ISO
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BCL2L1 mRNA
Vitamin E results in increased expression of BCL2L1 mRNA
CTD PMID:11444866 PMID:19244175 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Vitamin E results in decreased expression of BCL6 mRNA CTD PMID:19244175 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions EXP Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]] CTD PMID:9526112 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
EXP Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 mRNA]; Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 protein]
Vitamin E results in decreased expression of BECN1 protein
CTD PMID:19138675 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions EXP Vitamin E inhibits the reaction [Doxorubicin results in increased expression of BGLAP protein] CTD PMID:32810592 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression
multiple interactions
ISO Vitamin E results in decreased expression of BICD1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of BICD1 mRNA
CTD PMID:19244175 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434
JBrowse link
G Bicd2 BICD cargo adaptor 2 decreases expression ISO Vitamin E results in decreased expression of BICD2 mRNA CTD PMID:19244175 NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889
JBrowse link
G Bin1 bridging integrator 1 increases expression ISO Vitamin E results in increased expression of BIN1 mRNA CTD PMID:19244175 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions EXP
ISO
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNA
Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BIRC2 protein]
CTD PMID:11444866 PMID:15566391 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BIRC3 protein] CTD PMID:15566391 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Vitamin E inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein] CTD PMID:24664296 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bles03 basophilic leukemia expressed protein BLES03 increases expression ISO Vitamin E results in increased expression of C11ORF68 mRNA CTD PMID:19244175 NCBI chr 1:202,734,555...202,736,809
Ensembl chr 1:202,734,555...202,736,804
JBrowse link
G Blvra biliverdin reductase A increases expression ISO Vitamin E results in increased expression of BLVRA mRNA CTD PMID:19244175 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
JBrowse link
G Bmp2k BMP-2 inducible kinase decreases expression ISO Vitamin E results in decreased expression of BMP2K mRNA CTD PMID:19244175 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO Vitamin E results in increased expression of BMP4 mRNA CTD PMID:19244175 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bptf bromodomain PHD finger transcription factor multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of BPTF mRNA
Vitamin E results in decreased expression of BPTF mRNA
CTD PMID:19244175 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
JBrowse link
G Brd2 bromodomain containing 2 multiple interactions
decreases expression
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA
Vitamin E results in decreased expression of BRD2 mRNA
Vitamin E results in increased expression of BRD2 mRNA
CTD PMID:19244175 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
JBrowse link
G Brf2 BRF2, RNA polymerase III transcription initiation factor subunit increases expression ISO Vitamin E results in increased expression of BRF2 mRNA CTD PMID:19244175 NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator increases expression ISO Vitamin E results in increased expression of BRMS1 mRNA CTD PMID:19244175 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of BSCL2 mRNA
Vitamin E results in increased expression of BSCL2 mRNA
CTD PMID:19244175 NCBI chr 1:205,731,814...205,743,430
Ensembl chr 1:205,733,872...205,743,421
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Vitamin E results in increased expression of BST2 mRNA CTD PMID:19244175 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G C1s complement C1s increases expression ISO Vitamin E results in increased expression of C1S mRNA CTD PMID:19244175 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions EXP [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CA3 mRNA CTD PMID:11444866 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO Vitamin E results in decreased expression of CAAP1 mRNA CTD PMID:19244175 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Cab39 calcium binding protein 39 increases expression ISO Vitamin E results in increased expression of MO25 mRNA CTD PMID:19244175 NCBI chr 9:86,463,008...86,524,545
Ensembl chr 9:86,463,095...86,524,544
JBrowse link
G Cald1 caldesmon 1 decreases expression ISO Vitamin E results in decreased expression of CALD1 mRNA CTD PMID:19244175 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Calm3 calmodulin 3 increases expression ISO Vitamin E results in increased expression of CALM3 mRNA CTD PMID:19244175 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Calr calreticulin multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CALR mRNA
Vitamin E results in decreased expression of CALR mRNA
CTD PMID:19244175 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Calu calumenin multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CALU mRNA
Vitamin E results in increased expression of CALU mRNA
CTD PMID:19244175 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO Vitamin E results in increased expression of CAMK2B mRNA CTD PMID:19244175 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma decreases expression ISO Vitamin E results in decreased expression of CAMK2G mRNA CTD PMID:19244175 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 increases expression ISO Vitamin E results in increased expression of CAP1 mRNA CTD PMID:19244175 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO Vitamin E results in increased expression of CAPG mRNA CTD PMID:19244175 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Capn7 calpain 7 decreases expression ISO Vitamin E results in decreased expression of CAPN7 mRNA CTD PMID:19244175 NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905
JBrowse link
G Capns1 calpain, small subunit 1 increases expression ISO Vitamin E results in increased expression of CAPNS1 mRNA CTD PMID:19244175 NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795
JBrowse link
G Caprin2 caprin family member 2 decreases expression ISO Vitamin E results in decreased expression of CAPRIN2 mRNA CTD PMID:19244175 NCBI chr 4:181,806,105...181,860,754
Ensembl chr 4:181,806,575...181,860,830
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta increases expression ISO Vitamin E results in increased expression of CAPZB mRNA CTD PMID:19244175 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Casc3 CASC3 exon junction complex subunit multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of MLN51 mRNA
Vitamin E results in increased expression of MLN51 mRNA
CTD PMID:19244175 NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO
EXP
Vitamin E inhibits the reaction [cinnamaldehyde results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; Vitamin E inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased activity of CASP3 protein]
Vitamin E results in increased expression of CASP3 mRNA
Vitamin E inhibits the reaction [titanium dioxide results in increased activity of CASP3 protein]
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]; Vitamin E inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [Doxorubicin results in decreased expression of CASP3 mRNA]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]
CTD PMID:12117551 PMID:15566391 PMID:16054126 PMID:16973328 PMID:21628957 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO
EXP
Vitamin E results in increased expression of CASP9 mRNA
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]
CTD PMID:16973328 PMID:19244175 PMID:21628957 PMID:27353299 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases expression
decreases activity
affects expression
ISO
EXP
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; Vitamin E inhibits the reaction [Aluminum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]
Vitamin E results in increased expression of CAT protein
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] results in increased activity of CAT protein; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; [Vitamin E co-treated with Quercetin] inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; [Vitamin E co-treated with Sodium Selenite] inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; [Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]] which affects the abundance of Reactive Oxygen Species; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; Ginkgo biloba extract promotes the reaction [Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Carbofuran results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Food Additives affects the activity of CAT protein]; Vitamin E inhibits the reaction [Formaldehyde results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Methoxychlor results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Petroleum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of CAT protein]; Vitamin E promotes the reaction [Ginkgo biloba extract inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]
Vitamin E results in decreased activity of CAT protein
[Vitamin E co-treated with coenzyme Q10] inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [fipronil results in decreased activity of CAT protein]
Vitamin E affects the expression of CAT protein
CTD PMID:11597945 PMID:11834209 PMID:11955947 PMID:12355564 PMID:14535831 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAV1 protein] CTD PMID:12134086 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cavin1 caveolae associated protein 1 multiple interactions
increases expression
ISO Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAVIN1 protein]
Vitamin E results in increased expression of CAVIN1 mRNA
CTD PMID:19244175 PMID:21705337 NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression ISO Vitamin E results in increased expression of CAVIN3 mRNA CTD PMID:19244175 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO Vitamin E results in decreased expression of CBLB mRNA CTD PMID:19244175 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cbx5 chromobox 5 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CBX5 mRNA
Vitamin E results in decreased expression of CBX5 mRNA
CTD PMID:19244175 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Cbx6 chromobox 6 increases expression ISO Vitamin E results in increased expression of CBX6 mRNA CTD PMID:19244175 NCBI chr 7:111,372,979...111,383,109
Ensembl chr 7:111,372,980...111,383,091
JBrowse link
G Cbx7 chromobox 7 increases expression ISO Vitamin E results in increased expression of CBX7 mRNA CTD PMID:19244175 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cby1 chibby family member 1, beta catenin antagonist increases expression ISO Vitamin E results in increased expression of CBY1 mRNA CTD PMID:19244175 NCBI chr 7:111,216,835...111,223,305 JBrowse link
G Ccdc85b coiled-coil domain containing 85B multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of DIPA mRNA
Vitamin E results in increased expression of DIPA mRNA
CTD PMID:19244175 NCBI chr 1:202,763,645...202,764,631 JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 increases expression ISO Vitamin E results in increased expression of CCHCR1 mRNA CTD PMID:19244175 NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein] CTD PMID:19735175 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNA CTD PMID:16797527 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
affects expression
ISO
EXP
Vitamin E results in increased expression of CCND1 mRNA
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]
Vitamin E affects the expression of CCND1 mRNA; Vitamin E affects the expression of CCND1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CCND1 mRNA
CTD PMID:11444866 PMID:16298738 PMID:19244175 PMID:30935902 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Vitamin E results in increased expression of CCND2 mRNA CTD PMID:19244175 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 affects expression EXP Vitamin E affects the expression of CCND3 mRNA CTD PMID:15370891 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 affects expression EXP Vitamin E affects the expression of CCNE1 mRNA CTD PMID:16298738 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccnl1 cyclin L1 decreases expression ISO Vitamin E results in decreased expression of CCNL1 mRNA CTD PMID:19244175 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression ISO Vitamin E results in decreased expression of CPR8 mRNA CTD PMID:19244175 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Vitamin E results in increased expression of CCS mRNA CTD PMID:19244175 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915
JBrowse link
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 increases expression ISO Vitamin E results in increased expression of CD2BP2 mRNA CTD PMID:19244175 NCBI chr 1:181,809,399...181,815,269
Ensembl chr 1:181,809,406...181,813,448
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Vitamin E results in decreased expression of CD44 mRNA CTD PMID:19244175 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd63 Cd63 molecule increases expression ISO Vitamin E results in increased expression of CD63 mRNA CTD PMID:19244175 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Vitamin E inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Ethylmercuric Chloride results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Thimerosal results in increased expression of CD86 protein] CTD PMID:20457211 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cd99 CD99 molecule (Xg blood group) increases expression ISO Vitamin E results in increased expression of CD99 mRNA CTD PMID:19244175 NCBI chr20:54,418,239...54,422,882 JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Vitamin E results in decreased expression of CDC14B mRNA CTD PMID:19244175 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdc16 cell division cycle 16 decreases expression ISO Vitamin E results in decreased expression of CDC16 mRNA CTD PMID:19244175 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550
JBrowse link
G Cdc25b cell division cycle 25B increases expression ISO Vitamin E results in increased expression of CDC25B mRNA CTD PMID:19244175 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc27 cell division cycle 27 decreases expression ISO Vitamin E results in decreased expression of CDC27 mRNA CTD PMID:19244175 NCBI chr10:89,400,931...89,449,823
Ensembl chr10:89,400,940...89,449,736
JBrowse link
G Cdc42bpa CDC42 binding protein kinase alpha multiple interactions
increases expression
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CDC42BPA mRNA
Vitamin E results in increased expression of CDC42BPA mRNA
Vitamin E results in decreased expression of CDC42BPA mRNA
CTD PMID:19244175 NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein] CTD PMID:29940330 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh3 cadherin 3 increases expression ISO Vitamin E results in increased expression of CDH3 mRNA CTD PMID:19244175 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdk10 cyclin-dependent kinase 10 multiple interactions ISO [Selenium co-treated with Vitamin E] results in decreased expression of CDK10 mRNA CTD PMID:19244175 NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
JBrowse link
G Cdk13 cyclin-dependent kinase 13 decreases expression ISO Vitamin E results in decreased expression of CDK13 mRNA CTD PMID:19244175 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO Vitamin E results in increased expression of CDK4 mRNA CTD PMID:19244175 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression
multiple interactions
EXP
ISO
Vitamin E affects the expression of CDKN1A mRNA
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CDKN1A protein]
CTD PMID:16298738 PMID:30935902 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Vitamin E results in increased expression of CDKN1B protein CTD PMID:12352461 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 decreases expression ISO Vitamin E results in decreased expression of CDS1 mRNA CTD PMID:19244175 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Vitamin E inhibits the reaction [Ethanol results in decreased activity of CEBPA protein]; Vitamin E inhibits the reaction [Ethanol results in decreased expression of CEBPA protein] CTD PMID:16737972 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases response to substance ISO CEBPB results in increased susceptibility to Vitamin E CTD PMID:9359698 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cep164 centrosomal protein 164 increases expression ISO Vitamin E results in increased expression of CEP164 mRNA CTD PMID:19244175 NCBI chr 8:46,070,901...46,134,511
Ensembl chr 8:46,071,076...46,134,336
JBrowse link
G Cep170 centrosomal protein 170 decreases expression ISO Vitamin E results in decreased expression of CEP170 mRNA CTD PMID:19244175 NCBI chr13:88,669,672...88,754,011
Ensembl chr13:88,670,358...88,732,226
JBrowse link
G Cep290 centrosomal protein 290 decreases expression ISO Vitamin E results in decreased expression of CEP290 mRNA CTD PMID:19244175 NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392
JBrowse link
G Cep350 centrosomal protein 350 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNA
Vitamin E results in decreased expression of CEP350 mRNA
CTD PMID:19244175 NCBI chr13:68,023,327...68,164,478
Ensembl chr13:68,026,891...68,165,214
JBrowse link
G Cep57 centrosomal protein 57 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CEP57 mRNA
Vitamin E results in decreased expression of CEP57 mRNA
CTD PMID:19244175 NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:10,669,590...10,689,249
JBrowse link
G Cep97 centrosomal protein 97 decreases expression ISO Vitamin E results in decreased expression of CEP97 mRNA CTD PMID:19244175 NCBI chr11:44,683,503...44,711,471
Ensembl chr11:44,683,506...44,711,471
JBrowse link
G Cerk ceramide kinase increases expression ISO Vitamin E results in increased expression of CERK mRNA CTD PMID:19244175 NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759
JBrowse link
G Cert1 ceramide transporter 1 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of CERT1 mRNA
Vitamin E results in decreased expression of CERT1 mRNA
CTD PMID:19244175 NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Vitamin E results in increased expression of CES1 mRNA CTD PMID:19244175 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Vitamin E results in increased expression of CFLAR mRNA CTD PMID:19244175 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chd1 chromodomain helicase DNA binding protein 1 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CHD1 mRNA
Vitamin E results in decreased expression of CHD1 mRNA
CTD PMID:19244175 NCBI chr 1:56,661,743...56,729,119
Ensembl chr 1:56,664,054...56,728,125
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression ISO Vitamin E results in decreased expression of CHORDC1 mRNA CTD PMID:19244175 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Chpf chondroitin polymerizing factor multiple interactions ISO [Selenium co-treated with Vitamin E] results in decreased expression of CHPF mRNA CTD PMID:19244175 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
JBrowse link
G Chst3 carbohydrate sulfotransferase 3 increases expression ISO Vitamin E results in increased expression of CHST3 mRNA CTD PMID:19244175 NCBI chr20:28,114,387...28,152,046
Ensembl chr20:28,114,404...28,121,807
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Vitamin E results in increased expression of CHST6 mRNA CTD PMID:19244175 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
JBrowse link
G Ciao2b cytosolic iron-sulfur assembly component 2B increases expression ISO Vitamin E results in increased expression of CIAO2B mRNA CTD PMID:19244175 NCBI chr19:344,194...346,068
Ensembl chr19:344,203...346,068
JBrowse link
G Cib2 calcium and integrin binding family member 2 increases expression ISO Vitamin E results in increased expression of CIB2 mRNA CTD PMID:19244175 NCBI chr 8:54,930,265...54,947,157 JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO Vitamin E results in increased expression of CIRBP mRNA CTD PMID:19244175 NCBI chr 7:9,533,857...9,538,899 JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression ISO Vitamin E results in decreased expression of CKAP2 mRNA CTD PMID:19244175 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Ckb creatine kinase B increases expression ISO Vitamin E results in increased expression of CKB mRNA CTD PMID:19244175 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP Vitamin E inhibits the reaction [Diazinon results in increased activity of CKM protein] CTD PMID:23523949 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Clcc1 chloride channel CLIC-like 1 decreases expression ISO Vitamin E results in decreased expression of CLCC1 mRNA CTD PMID:19244175 NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of CLCN3 mRNA
Vitamin E results in decreased expression of CLCN3 mRNA
CTD PMID:19244175 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Cldn4 claudin 4 multiple interactions EXP Vitamin E inhibits the reaction [phoxim results in decreased expression of CLDN4 mRNA] CTD PMID:30003487 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Clec3b C-type lectin domain family 3, member B multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of TNA mRNA
Vitamin E results in increased expression of TNA mRNA
CTD PMID:19244175 NCBI chr 8:122,810,091...122,817,039
Ensembl chr 8:122,810,149...122,815,835
JBrowse link
G Clic1 chloride intracellular channel 1 increases expression ISO Vitamin E results in increased expression of CLIC1 mRNA CTD PMID:19244175 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 decreases expression ISO Vitamin E results in decreased expression of CLIP1 mRNA CTD PMID:19244175 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin multiple interactions
increases expression