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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:UNC1999
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Accession:CHEBI:230504 term browser browse the term
Definition:UNC1999 is a SAM-competitive, potent and selective inhibitor of EZH2/1.
Synonyms:related_synonym: Formula=C33H43N7O2;   InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42);   InChIKey=DPJNKUOXBZSZAI-UHFFFAOYSA-N;   SMILES=O=C1C(CNC(C2=C3C=NN(C(C)C)C3=CC(C4=CN=C(N5CCN(C(C)C)CC5)C=C4)=C2)=O)=C(CCC)C=C(C)N1
 xref: CAS:1431612-23-5
 xref_mesh: MESH:C000619732


show annotations for term's descendants           Sort by:
UNC1999 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxa2 forkhead box A2 multiple interactions ISO UNC1999 inhibits the reaction [Cadmium results in decreased expression of FOXA2 mRNA] CTD PMID:36321828 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Hopx HOP homeobox multiple interactions ISO UNC1999 inhibits the reaction [Cadmium results in decreased expression of HOPX mRNA] CTD PMID:36321828 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      atom 19892
        nonmetal atom 19849
          carbon atom 19802
            organic molecular entity 19775
              UNC1999 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            UNC1999 2
paths to the root