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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:StemRegenin 1
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Accession:CHEBI:230484 term browser browse the term
Definition:Inhibitor of the aryl hydrocarbon receptor
Synonyms:related_synonym: Formula=C24H23N5OS;   InChI=1S/C24H23N5OS/c1-15(2)29-14-26-21-23(25-12-11-16-7-9-17(30)10-8-16)27-22(28-24(21)29)19-13-31-20-6-4-3-5-18(19)20/h3-10,13-15,30H,11-12H2,1-2H3,(H,25,27,28);   InChIKey=BGFHMYJZJZLMHW-UHFFFAOYSA-N;   SMILES=CC(C)N1C=NC2=C(NCCC3=CC=C(C=C3)O)N=C(C4=CSC5=CC=CC=C45)N=C21;   SR1
 xref: CAS:1227633-49-9
 xref_mesh: MESH:C552240


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StemRegenin 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO StemRegenin 1 results in decreased expression of AHRR mRNA CTD PMID:20688981 NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression 		ISO StemRegenin 1 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
StemRegenin 1 results in decreased expression of CYP1B1 mRNA 		CTD PMID:20688981 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Kitlg KIT ligand multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein] CTD PMID:33421718 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein] CTD PMID:33421718 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein] CTD PMID:33421718 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006 		JBrowse link
G Thpo thrombopoietin multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 Ensembl chr11:93,686,834...93,693,320 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          carbon atom 20710
            organic molecular entity 20710
              StemRegenin 1 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            StemRegenin 1 9
paths to the root