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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:StemRegenin 1
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Accession:CHEBI:230484 term browser browse the term
Definition:Inhibitor of the aryl hydrocarbon receptor
Synonyms:related_synonym: Formula=C24H23N5OS;   InChI=1S/C24H23N5OS/c1-15(2)29-14-26-21-23(25-12-11-16-7-9-17(30)10-8-16)27-22(28-24(21)29)19-13-31-20-6-4-3-5-18(19)20/h3-10,13-15,30H,11-12H2,1-2H3,(H,25,27,28);   InChIKey=BGFHMYJZJZLMHW-UHFFFAOYSA-N;   SMILES=CC(C)N1C=NC2=C(NCCC3=CC=C(C=C3)O)N=C(C4=CSC5=CC=CC=C45)N=C21;   SR1
 xref: CAS:1227633-49-9
 xref_mesh: MESH:C552240



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StemRegenin 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO StemRegenin 1 results in decreased expression of AHRR mRNA CTD PMID:20688981 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression
ISO StemRegenin 1 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
StemRegenin 1 results in decreased expression of CYP1B1 mRNA
CTD PMID:20688981 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Il6 interleukin 6 multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kitlg KIT ligand multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein] CTD PMID:33421718 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein] CTD PMID:33421718 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein] CTD PMID:33421718 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Thpo thrombopoietin multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 Ensembl chr11:80,182,820...80,188,167 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19878
    chemical entity 19876
      atom 19876
        nonmetal atom 19798
          carbon atom 19752
            organic molecular entity 19752
              StemRegenin 1 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19878
    subatomic particle 19876
      composite particle 19876
        hadron 19876
          baryon 19876
            nucleon 19876
              atomic nucleus 19876
                atom 19876
                  main group element atom 19815
                    p-block element atom 19815
                      carbon group element atom 19755
                        carbon atom 19752
                          organic molecular entity 19752
                            StemRegenin 1 9
paths to the root