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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:StemRegenin 1
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Accession:CHEBI:230484 term browser browse the term
Definition:Inhibitor of the aryl hydrocarbon receptor
Synonyms:related_synonym: Formula=C24H23N5OS;   InChI=1S/C24H23N5OS/c1-15(2)29-14-26-21-23(25-12-11-16-7-9-17(30)10-8-16)27-22(28-24(21)29)19-13-31-20-6-4-3-5-18(19)20/h3-10,13-15,30H,11-12H2,1-2H3,(H,25,27,28);   InChIKey=BGFHMYJZJZLMHW-UHFFFAOYSA-N;   SMILES=CC(C)N1C=NC2=C(NCCC3=CC=C(C=C3)O)N=C(C4=CSC5=CC=CC=C45)N=C21;   SR1
 xref: CAS:1227633-49-9
 xref_mesh: MESH:C552240


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StemRegenin 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO StemRegenin 1 results in decreased expression of AHRR mRNA CTD PMID:20688981 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression		 ISO StemRegenin 1 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
StemRegenin 1 results in decreased expression of CYP1B1 mRNA		 CTD PMID:20688981 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kitlg KIT ligand multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein] CTD PMID:33421718 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein] CTD PMID:33421718 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO StemRegenin 1 inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein] CTD PMID:33421718 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Thpo thrombopoietin multiple interactions ISO StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with FLT3LG protein co-treated with IL6 protein] CTD PMID:26160960 Ensembl chr11:80,182,820...80,188,167 JBrowse link
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      atom 19892
        nonmetal atom 19849
          carbon atom 19802
            organic molecular entity 19775
              StemRegenin 1 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            StemRegenin 1 9
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